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Volumn 230, Issue 2, 2013, Pages 171-176

Long-term use of statins reduces the risk of hospitalization fordementia

Author keywords

Alzheimer's disease; Dementia; Healthcare Utilization Database; Lipid lowering agents; Monte Carlo sensitivity analysis; Record linkage; Rule out sensitivity analysis; Statins; Unmeasured confounders

Indexed keywords

ATORVASTATIN; CERIVASTATIN; FLUINDOSTATIN; PRAVASTATIN; ROSUVASTATIN; SIMVASTATIN;

EID: 84884537112     PISSN: 00219150     EISSN: 18791484     Source Type: Journal    
DOI: 10.1016/j.atherosclerosis.2013.07.009     Document Type: Article
Times cited : (33)

References (44)
  • 1
    • 0028227379 scopus 로고
    • Cardiovascular disease and distribution of cognitive function in elderly people: the Rotterdam Study
    • Breteler M.M., Claus J.J., Grobbee D.E., Hofman A. Cardiovascular disease and distribution of cognitive function in elderly people: the Rotterdam Study. BMJ 1994, 308:1604-1608.
    • (1994) BMJ , vol.308 , pp. 1604-1608
    • Breteler, M.M.1    Claus, J.J.2    Grobbee, D.E.3    Hofman, A.4
  • 2
    • 24344451279 scopus 로고    scopus 로고
    • Dementia and Alzheimer's disease incidence in relationship to cardiovascular disease in the Cardiovascular Health Study cohort
    • Newman A.B., Fitzpatrick A.L., Lopez O., et al. Dementia and Alzheimer's disease incidence in relationship to cardiovascular disease in the Cardiovascular Health Study cohort. JAm Geriatr Soc 2005, 53:1101-1107.
    • (2005) JAm Geriatr Soc , vol.53 , pp. 1101-1107
    • Newman, A.B.1    Fitzpatrick, A.L.2    Lopez, O.3
  • 3
    • 79960205374 scopus 로고    scopus 로고
    • ESC/EAS Guidelines for the management of dyslipidaemias: the Task Force for the management of dyslipidaemias of the European Society of Cardiology (ESC) and the European Atherosclerosis Society (EAS)
    • European Society of Cardiology (ESC) European Atherosclerosis Society (EAS) et al.
    • Catapano A.L., Reiner Z., De Backer G., European Society of Cardiology (ESC), European Atherosclerosis Society (EAS), et al. ESC/EAS Guidelines for the management of dyslipidaemias: the Task Force for the management of dyslipidaemias of the European Society of Cardiology (ESC) and the European Atherosclerosis Society (EAS). Atherosclerosis 2011, 217:3-46.
    • (2011) Atherosclerosis , vol.217 , pp. 3-46
    • Catapano, A.L.1    Reiner, Z.2    De Backer, G.3
  • 4
    • 67650094615 scopus 로고    scopus 로고
    • The benefits of statins in people without established cardiovascular disease but with cardiovascular risk factors: meta-analysis of randomized controlled trials
    • Brugts J.J., Yetgin T., Hoeks S.E., et al. The benefits of statins in people without established cardiovascular disease but with cardiovascular risk factors: meta-analysis of randomized controlled trials. BMJ 2009, 338:b2376.
    • (2009) BMJ , vol.338
    • Brugts, J.J.1    Yetgin, T.2    Hoeks, S.E.3
  • 5
    • 84867563393 scopus 로고    scopus 로고
    • Mechanisms and clinical evidence of the pleiotropic effects of the hydroxy-methyl-glutaryl-CoA reductase inhibitors in central nervous system disorders: a comprehensive review
    • Yanuck D., Mihos C.G., Santana O. Mechanisms and clinical evidence of the pleiotropic effects of the hydroxy-methyl-glutaryl-CoA reductase inhibitors in central nervous system disorders: a comprehensive review. Int J Neurosci 2012, 122:619-629.
    • (2012) Int J Neurosci , vol.122 , pp. 619-629
    • Yanuck, D.1    Mihos, C.G.2    Santana, O.3
  • 7
    • 0038350752 scopus 로고    scopus 로고
    • The role of lipid-lowering drugs in cognitive function: a meta-analysis of observational studies
    • Etminan M., Gill S., Samii A. The role of lipid-lowering drugs in cognitive function: a meta-analysis of observational studies. Pharmacotherapy 2003, 6:726-730.
    • (2003) Pharmacotherapy , vol.6 , pp. 726-730
    • Etminan, M.1    Gill, S.2    Samii, A.3
  • 8
    • 80955135450 scopus 로고    scopus 로고
    • Statins and serum cholesterol's associations with incident dementia and mild cognitive impairment
    • Beydoun M.A., Beason-Held L.L., Kitner-Trolo M.H., et al. Statins and serum cholesterol's associations with incident dementia and mild cognitive impairment. JEpidemiol Community Health 2011, 65:949-957.
    • (2011) JEpidemiol Community Health , vol.65 , pp. 949-957
    • Beydoun, M.A.1    Beason-Held, L.L.2    Kitner-Trolo, M.H.3
  • 9
    • 43249094747 scopus 로고    scopus 로고
    • Statins, incident Alzheimer's disease, change in cognitive function, and neuropathology
    • Arvanitakis Z., Schneider J.A., Wilson R.S., et al. Statins, incident Alzheimer's disease, change in cognitive function, and neuropathology. Neurology 2008, 70:1795-1802.
    • (2008) Neurology , vol.70 , pp. 1795-1802
    • Arvanitakis, Z.1    Schneider, J.A.2    Wilson, R.S.3
  • 10
    • 0037031061 scopus 로고    scopus 로고
    • MRC/BHF heart protection study of cholesterol lowering with simvastatin in 20,536 high-risk individuals: a randomised placebo-controlled trial
    • Group HPSC
    • Group HPSC MRC/BHF heart protection study of cholesterol lowering with simvastatin in 20,536 high-risk individuals: a randomised placebo-controlled trial. Lancet 2002, 360:7-22.
    • (2002) Lancet , vol.360 , pp. 7-22
  • 11
    • 0037164314 scopus 로고    scopus 로고
    • Pravastatin in elderly individuals at risk of vascular disease (PROSPER): a randomised controlled trial
    • PROSPER Study Group PROspective Study of Pravastatin in the Elderly at Risk et al.
    • Shepherd J., Blauw G.J., Murphy M.B., PROSPER Study Group, PROspective Study of Pravastatin in the Elderly at Risk, et al. Pravastatin in elderly individuals at risk of vascular disease (PROSPER): a randomised controlled trial. Lancet 2002, 360:1623-1630.
    • (2002) Lancet , vol.360 , pp. 1623-1630
    • Shepherd, J.1    Blauw, G.J.2    Murphy, M.B.3
  • 12
    • 77649327593 scopus 로고    scopus 로고
    • Pharmacoepidemiological research and the linking of electronic healthcare databases available in the Italian region of Lombardy
    • Corrao G., Cesana G., Merlino L. Pharmacoepidemiological research and the linking of electronic healthcare databases available in the Italian region of Lombardy. Biomed Stat Clin Epidemiol 2008, 2:117-125.
    • (2008) Biomed Stat Clin Epidemiol , vol.2 , pp. 117-125
    • Corrao, G.1    Cesana, G.2    Merlino, L.3
  • 13
    • 79954592659 scopus 로고    scopus 로고
    • Risk factors for dementia in patients over 65 with diabetes
    • Parikh N.M., Morgan R.O., Kunik M.E., et al. Risk factors for dementia in patients over 65 with diabetes. Int J Geriatr Psychiatry 2011, 26:749-757.
    • (2011) Int J Geriatr Psychiatry , vol.26 , pp. 749-757
    • Parikh, N.M.1    Morgan, R.O.2    Kunik, M.E.3
  • 14
    • 61849135671 scopus 로고    scopus 로고
    • Long-term persistence with statin therapy: a nationwide register study in Finland
    • Helin-Salmivaara A., Lavikainen P., Korhonen M.J., et al. Long-term persistence with statin therapy: a nationwide register study in Finland. Clin Ther 2008, 30:2228-2240.
    • (2008) Clin Ther , vol.30 , pp. 2228-2240
    • Helin-Salmivaara, A.1    Lavikainen, P.2    Korhonen, M.J.3
  • 15
    • 47649092867 scopus 로고    scopus 로고
    • Immeasurable time bias in observational studies of drug effects on mortality
    • Suissa S. Immeasurable time bias in observational studies of drug effects on mortality. Am J Epidemiol 2008, 168:329-335.
    • (2008) Am J Epidemiol , vol.168 , pp. 329-335
    • Suissa, S.1
  • 17
    • 0000154003 scopus 로고
    • The analysis of case-control studies
    • IARC Scientific Publications N° 32, International Agency for Research on Cancer, Lyon
    • Breslow N.E., Day N.E. The analysis of case-control studies. Statistical methods in cancer research 1980, Vol. I. IARC Scientific Publications N° 32, International Agency for Research on Cancer, Lyon.
    • (1980) Statistical methods in cancer research , vol.1
    • Breslow, N.E.1    Day, N.E.2
  • 18
    • 0035701428 scopus 로고    scopus 로고
    • Sensitivity analysis, Monte-Carlo risk analysis and Bayesian uncertainty assessment
    • Greenland S. Sensitivity analysis, Monte-Carlo risk analysis and Bayesian uncertainty assessment. Risk Anal 2001, 21:579-583.
    • (2001) Risk Anal , vol.21 , pp. 579-583
    • Greenland, S.1
  • 19
    • 84859184996 scopus 로고    scopus 로고
    • Association of LDL cholesterol, non-HDL cholesterol, and apolipoprotein B levels with risk of cardiovascular events among patients treated with statins
    • Boekholdt S.M., Arsenault B.J., Mora S., et al. Association of LDL cholesterol, non-HDL cholesterol, and apolipoprotein B levels with risk of cardiovascular events among patients treated with statins. JAMA 2012, 307:1302-1309.
    • (2012) JAMA , vol.307 , pp. 1302-1309
    • Boekholdt, S.M.1    Arsenault, B.J.2    Mora, S.3
  • 20
    • 67749114631 scopus 로고    scopus 로고
    • Midlife serum cholesterol and increased risk of Alzheimer's disease and vascular dementia three decades later
    • Solomon A., Kivipelto M., Wolozin B., Zhou J., Whitmer R.A. Midlife serum cholesterol and increased risk of Alzheimer's disease and vascular dementia three decades later. Dement Geriatr Cogn Disord 2009, 28:75-80.
    • (2009) Dement Geriatr Cogn Disord , vol.28 , pp. 75-80
    • Solomon, A.1    Kivipelto, M.2    Wolozin, B.3    Zhou, J.4    Whitmer, R.A.5
  • 21
    • 84866843285 scopus 로고    scopus 로고
    • External adjustment for unmeasured confounders improved drug-outcome association estimates based on health care utilization data
    • Corrao G., Nicotra F., Parodi A., et al. External adjustment for unmeasured confounders improved drug-outcome association estimates based on health care utilization data. JClin Epidemiol 2012, 65:1190-1199.
    • (2012) JClin Epidemiol , vol.65 , pp. 1190-1199
    • Corrao, G.1    Nicotra, F.2    Parodi, A.3
  • 22
    • 79958234542 scopus 로고    scopus 로고
    • Depression and risk of developing dementia
    • Byers A.L., Yaffe K. Depression and risk of developing dementia. Nat Rev Neurol 2011, 7:323-331.
    • (2011) Nat Rev Neurol , vol.7 , pp. 323-331
    • Byers, A.L.1    Yaffe, K.2
  • 23
    • 0034710203 scopus 로고    scopus 로고
    • Depression is a risk factor for noncompliance with medical treatment
    • DiMatteo M.R., Lepper H.S., Croghan T.W. Depression is a risk factor for noncompliance with medical treatment. Arch Intern Med 2000, 160:2101-2107.
    • (2000) Arch Intern Med , vol.160 , pp. 2101-2107
    • DiMatteo, M.R.1    Lepper, H.S.2    Croghan, T.W.3
  • 24
    • 33744495314 scopus 로고    scopus 로고
    • Sensitivity analysis and external adjustment for unmeasured confounders in epidemiologic database studies of therapeutics
    • Schneeweiss S. Sensitivity analysis and external adjustment for unmeasured confounders in epidemiologic database studies of therapeutics. Pharmacoepidemiol Drug Saf 2006, 15:291-303.
    • (2006) Pharmacoepidemiol Drug Saf , vol.15 , pp. 291-303
    • Schneeweiss, S.1
  • 25
    • 84861828191 scopus 로고    scopus 로고
    • Statin use and risk of depression in patients with coronary heart disease: longitudinal data from the Heart and Soul Study
    • Otte C., Zhao S., Whooley M.A. Statin use and risk of depression in patients with coronary heart disease: longitudinal data from the Heart and Soul Study. JClin Psychiatry 2012, 73:610-615.
    • (2012) JClin Psychiatry , vol.73 , pp. 610-615
    • Otte, C.1    Zhao, S.2    Whooley, M.A.3
  • 26
    • 0942278990 scopus 로고    scopus 로고
    • Association between statin use and Alzheimer's disease
    • Zamrini E., McGwin G., Roseman J.M. Association between statin use and Alzheimer's disease. Neuroepidemiology 2004, 23:94-98.
    • (2004) Neuroepidemiology , vol.23 , pp. 94-98
    • Zamrini, E.1    McGwin, G.2    Roseman, J.M.3
  • 27
    • 67649252917 scopus 로고    scopus 로고
    • Use of statins and incidence of dementia and cognitive impairment without dementia in a cohort study
    • Cramer C., Haan M.N., Galea S., Langa K.M., Kalbfleisch J.D. Use of statins and incidence of dementia and cognitive impairment without dementia in a cohort study. Neurology 2008, 71:344-350.
    • (2008) Neurology , vol.71 , pp. 344-350
    • Cramer, C.1    Haan, M.N.2    Galea, S.3    Langa, K.M.4    Kalbfleisch, J.D.5
  • 28
    • 1542319758 scopus 로고    scopus 로고
    • Atorvastatin: gold standard for prophylaxis of myocardial ischemia and stroke - comparison of the clinical benefit of statins on the basis of randomized controlled endpoint studies
    • Gresser U., Gathof B.S. Atorvastatin: gold standard for prophylaxis of myocardial ischemia and stroke - comparison of the clinical benefit of statins on the basis of randomized controlled endpoint studies. Eur J Med Res 2004, 9:1-17.
    • (2004) Eur J Med Res , vol.9 , pp. 1-17
    • Gresser, U.1    Gathof, B.S.2
  • 29
    • 34548299453 scopus 로고    scopus 로고
    • Simvastatin is associated with a reduced incidence of dementia and Parkinson's disease
    • Wolozin B., Wang S.W., Li N.-C., Lee A., Lee T.A., Kazis L.E. Simvastatin is associated with a reduced incidence of dementia and Parkinson's disease. BMC Med 2007, 5:20.
    • (2007) BMC Med , vol.5 , pp. 20
    • Wolozin, B.1    Wang, S.W.2    Li, N.-C.3    Lee, A.4    Lee, T.A.5    Kazis, L.E.6
  • 30
    • 58249089520 scopus 로고    scopus 로고
    • Statins are associated with a reduced risk of Alzheimer disease regardless of lipophilicity. The Rotterdam Study
    • Haag M.D., Hofman A., Koudstaal P.J., Stricker B.H., Breteler M.M. Statins are associated with a reduced risk of Alzheimer disease regardless of lipophilicity. The Rotterdam Study. JNeurol Neurosurg Psychiatry 2009, 80:13-17.
    • (2009) JNeurol Neurosurg Psychiatry , vol.80 , pp. 13-17
    • Haag, M.D.1    Hofman, A.2    Koudstaal, P.J.3    Stricker, B.H.4    Breteler, M.M.5
  • 31
    • 81355164295 scopus 로고    scopus 로고
    • Cholesterol and statins in Alzheimer's disease
    • Shepardson N.E., Shankar G.M., Selkoe D.J. Cholesterol and statins in Alzheimer's disease. Arch Neurol 2011, 68:1385-1392.
    • (2011) Arch Neurol , vol.68 , pp. 1385-1392
    • Shepardson, N.E.1    Shankar, G.M.2    Selkoe, D.J.3
  • 32
  • 33
    • 79956277464 scopus 로고    scopus 로고
    • Incidence of dementia is increased in type 2 diabetes and reduced by the use of sulfonylureas and metformin
    • Hsu C.C., Wahlqvist M.L., Lee M.S., Tsai H.N. Incidence of dementia is increased in type 2 diabetes and reduced by the use of sulfonylureas and metformin. JAlzheimers Dis 2011, 24:485-493.
    • (2011) JAlzheimers Dis , vol.24 , pp. 485-493
    • Hsu, C.C.1    Wahlqvist, M.L.2    Lee, M.S.3    Tsai, H.N.4
  • 34
    • 81755181505 scopus 로고    scopus 로고
    • The association of antihypertensive medication use with risk of cognitive decline and dementia: a meta-analysis of longitudinal studies
    • Chang-Quan H., Hui W., Chao-Min W., et al. The association of antihypertensive medication use with risk of cognitive decline and dementia: a meta-analysis of longitudinal studies. Int J Clin Pract 2011, 65:1295-1305.
    • (2011) Int J Clin Pract , vol.65 , pp. 1295-1305
    • Chang-Quan, H.1    Hui, W.2    Chao-Min, W.3
  • 35
    • 84889420194 scopus 로고    scopus 로고
    • Overview of automated databases in pharmacoepidemiology
    • Wiley, Chichester, UK, B.L. Strom (Ed.)
    • Strom B.L. Overview of automated databases in pharmacoepidemiology. Pharmacoepidemiology 2000, 219-222. Wiley, Chichester, UK. 3rd ed. B.L. Strom (Ed.).
    • (2000) Pharmacoepidemiology , pp. 219-222
    • Strom, B.L.1
  • 36
    • 0142157169 scopus 로고    scopus 로고
    • Evaluating medication effects outside of clinical trials: new-user designs
    • Ray W.A. Evaluating medication effects outside of clinical trials: new-user designs. Am J Epidemiol 2003, 158:915-920.
    • (2003) Am J Epidemiol , vol.158 , pp. 915-920
    • Ray, W.A.1
  • 37
    • 79955075235 scopus 로고    scopus 로고
    • Nonexperimental comparative effectiveness research using linked healthcare databases
    • Stürmer T., Funk M.J., Poole C., Brookhart M.A. Nonexperimental comparative effectiveness research using linked healthcare databases. Epidemiology 2011, 22:298-301.
    • (2011) Epidemiology , vol.22 , pp. 298-301
    • Stürmer, T.1    Funk, M.J.2    Poole, C.3    Brookhart, M.A.4
  • 38
    • 33744966617 scopus 로고    scopus 로고
    • Recommendations for evaluating compliance and persistence with hypertension therapy using retrospective data
    • Halpern M.T., Khan Z.M., Schmier J.K., et al. Recommendations for evaluating compliance and persistence with hypertension therapy using retrospective data. Hypertension 2006, 47:1039-1048.
    • (2006) Hypertension , vol.47 , pp. 1039-1048
    • Halpern, M.T.1    Khan, Z.M.2    Schmier, J.K.3
  • 39
    • 18044398603 scopus 로고    scopus 로고
    • Areview of uses of health care utilization databases for epidemiologic research on therapeutics
    • Schneeweiss S., Avorn J. Areview of uses of health care utilization databases for epidemiologic research on therapeutics. JClin Epidemiol 2005, 58:323-337.
    • (2005) JClin Epidemiol , vol.58 , pp. 323-337
    • Schneeweiss, S.1    Avorn, J.2
  • 41
    • 0036710820 scopus 로고    scopus 로고
    • The accuracy of medicare claims data in identifying Alzheimer's disease
    • Taylor D.H., Fillenbaum G.G., Ezell M.E. The accuracy of medicare claims data in identifying Alzheimer's disease. JClin Epidemiol 2002, 55:929-937.
    • (2002) JClin Epidemiol , vol.55 , pp. 929-937
    • Taylor, D.H.1    Fillenbaum, G.G.2    Ezell, M.E.3
  • 42
    • 0034993198 scopus 로고    scopus 로고
    • Diagnosis of vascular dementia and Alzheimer's disease
    • Román G. Diagnosis of vascular dementia and Alzheimer's disease. Int J Clin Pract Suppl 2001, 120:9-13.
    • (2001) Int J Clin Pract Suppl , vol.120 , pp. 9-13
    • Román, G.1
  • 44
    • 77957038341 scopus 로고    scopus 로고
    • 3-Hydroxy-3-methylglutaryl-coenzyme A reductase inhibitors in the treatment of central nervous system diseases
    • Willey J.Z., Elkind M.S. 3-Hydroxy-3-methylglutaryl-coenzyme A reductase inhibitors in the treatment of central nervous system diseases. Arch Neurol 2010, 67:1062-1067.
    • (2010) Arch Neurol , vol.67 , pp. 1062-1067
    • Willey, J.Z.1    Elkind, M.S.2


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