The role of HIF1α in renal cell carcinoma tumorigenesis

Journal of Molecular Medicine

Volumn 92, Issue 8, 2014, Pages 825-836

  Gudas, Lorraine J ^a   Fu, Leiping ^a   Minton, Denise R ^a,b   Mongan, Nigel P ^c   Nanus, David M ^a  

^a WEILL CORNELL MEDICAL COLLEGE   (United States)

^b Weill Cornell Graduate School of Biomedical Sciences   (United States)

^c UNIVERSITY OF NOTTINGHAM   (United Kingdom)

Author keywords

Cancer stem cells; Carcinogenesis; Clear cell renal cell carcinoma; Hypoxia inducible factor 1 ; Kidney cancer; Review

Indexed keywords

BEVACIZUMAB; EPIDERMAL GROWTH FACTOR RECEPTOR 2; EVEROLIMUS; HYPOXIA INDUCIBLE FACTOR 1ALPHA; HYPOXIA INDUCIBLE FACTOR 2ALPHA; MAMMALIAN TARGET OF RAPAMYCIN COMPLEX 1; MAMMALIAN TARGET OF RAPAMYCIN COMPLEX 2; N (3 METHYLPHENYL) 4 (4 PYRIDINYL) 2 THIAZOLAMINE; PROTEIN TYROSINE KINASE INHIBITOR; TEMSIROLIMUS; TRANSCRIPTION FACTOR YY1; VON HIPPEL LINDAU PROTEIN; X BOX BINDING PROTEIN 1;

ANAEROBIC GLYCOLYSIS; AUTOPHAGY; CANCER CHEMOTHERAPY; CANCER GROWTH; CANCER SIZE; CANCER STEM CELL; CANCER SURVIVAL; CARCINOGENESIS; CELL NUCLEUS; CELL PROLIFERATION; CHROMATIN IMMUNOPRECIPITATION; CHROMOSOME 14Q; CHROMOSOME LOSS; CLEAR CELL CARCINOMA; CYTOPLASM; DISEASE FREE SURVIVAL; GENE DELETION; GENE OVEREXPRESSION; HEMATOPOIETIC STEM CELL; HETEROZYGOSITY LOSS; HUMAN; IMMUNOHISTOCHEMISTRY; KIDNEY CARCINOMA; KIDNEY PROXIMAL TUBULE; KIDNEY TUBULE CELL; NONHUMAN; OVERALL SURVIVAL; PATHOGENESIS; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN INTERACTION; RENAL CELL CARCINOMA CELL LINE; REVIEW; RNA SEQUENCE; SINGLE NUCLEOTIDE POLYMORPHISM; STEM CELL; TISSUE MICROARRAY; TRIPLE NEGATIVE BREAST CANCER; VON HIPPEL LINDAU DISEASE; ANIMAL; CARCINOMA, RENAL CELL; CELL TRANSFORMATION; DISEASE COURSE; DISEASE MODEL; GENE EXPRESSION; GENETICS; KIDNEY NEOPLASMS; METABOLISM; MOLECULARLY TARGETED THERAPY; MOUSE; MUTATION; PATHOLOGY;

ANIMALS; CARCINOMA, RENAL CELL; CELL TRANSFORMATION, NEOPLASTIC; DISEASE MODELS, ANIMAL; DISEASE PROGRESSION; GENE DELETION; GENE EXPRESSION; HUMANS; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; KIDNEY NEOPLASMS; MICE; MOLECULAR TARGETED THERAPY; MUTATION; NEOPLASTIC STEM CELLS; STEM CELLS; VON HIPPEL-LINDAU DISEASE;

EID: 84906789939     PISSN: 09462716     EISSN: 14321440     Source Type: Journal    
DOI: 10.1007/s00109-014-1180-z     Document Type: Review

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