Prognostic markers in stage i oral cavity squamous cell carcinoma

Laryngoscope

Volumn 123, Issue 10, 2013, Pages 2435-2441

  Dunkel, Johannes ^a,b   Vaittinen, Samuli ^b,c   Grénman, Reidar ^c   Kinnunen, Ilpo ^c   Irjala, Heikki ^a  

^a UNIVERSITY OF TURKU   (Finland)

^b UNIVERSITY OF TURKU   (Finland)

^c TURKU UNIVERSITY HOSPITAL   (Finland)

Author keywords

biomarker; CD44; head and neck cancer; head and neck squamous cell carcinoma; HIF 1 ; immunohistochemistry; p16; podoplanin; prognosis

Indexed keywords

HERMES ANTIGEN; HYPOXIA INDUCIBLE FACTOR 1ALPHA; KI 67 ANTIGEN; PODOPLANIN; PROTEIN P16;

ADULT; AGED; ARTICLE; CANCER PATIENT; CANCER PROGNOSIS; CANCER STAGING; CANCER SURVIVAL; CLINICAL ARTICLE; DISEASE COURSE; FEMALE; FOLLOW UP; HUMAN; IMMUNOHISTOCHEMISTRY; MALE; MOUTH SQUAMOUS CELL CARCINOMA; PRIORITY JOURNAL; PROTEIN EXPRESSION; RETROSPECTIVE STUDY;

BIOMARKER; CD44; HEAD AND NECK CANCER; HEAD AND NECK SQUAMOUS CELL CARCINOMA; HIF-1Α; IMMUNOHISTOCHEMISTRY; P16; PODOPLANIN; PROGNOSIS;

ADULT; AGED; AGED, 80 AND OVER; ANTIGENS, CD44; CARCINOMA, SQUAMOUS CELL; DISEASE-FREE SURVIVAL; FEMALE; HEAD AND NECK NEOPLASMS; HUMANS; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; IMMUNOHISTOCHEMISTRY; MALE; MEMBRANE GLYCOPROTEINS; MIDDLE AGED; MOUTH FLOOR; PROGNOSIS; TONGUE NEOPLASMS;

EID: 84884985607     PISSN: 0023852X     EISSN: 15314995     Source Type: Journal    
DOI: 10.1002/lary.23888     Document Type: Article

References (31)

1. Warnakulasuriya S,. Global epidemiology of oral and oropharyngeal cancer. Oral Oncol 2009; 45: 309-316.
2. Ferlay J, Shin H-R, Bray F, et al. Estimates of worldwide burden of cancer in 2008: GLOBOCAN 2008. Int J Cancer 2010; 127: 2893-2917.
3. Bessell A, Glenny A-M, Furness S, et al. Interventions for the treatment of oral and oropharyngeal cancers: surgical treatment. Cochrane Database Syst Rev 2011;(9): CD006205.
4. Zatterstrom UK, Wennerberg J, Ewers SB, Willen R, Attewell R,. Prognostic factors in head and neck cancer: histologic grading, DNA ploidy, and nodal status. Head Neck 1991; 13: 477-487.
5. Schliephake H,. Prognostic relevance of molecular markers of oral cancer-a review. Int J Oral Maxillofac Surg 2003; 32: 233-245.
6. Weigel MT, Dowsett M,. Current and emerging biomarkers in breast cancer: prognosis and prediction. Endocr Relat Cancer 2010; 17: R245-R262.
7. Hoogsteen IJ, Marres HA, Bussink J, van der Kogel AJ, Kaanders JH,. Tumor microenvironment in head and neck squamous cell carcinomas: predictive value and clinical relevance of hypoxic markers. A review. Head Neck 2007; 29: 591-604.
8. Wang SJ, Bourguignon LY,. Role of hyaluronan-mediated CD44 signaling in head and neck squamous cell carcinoma progression and chemoresistance. Am J Pathol 2010; 178: 956-963.
9. Yuan P, Temam S, El-Naggar A, et al. Overexpression of podoplanin in oral cancer and its association with poor clinical outcome. Cancer 2006; 107: 563-569.
10. Nakao Y, Yang X, Yokoyama M, et al. Induction of p16 during immortalization by HPV 16 and 18 and not during malignant transformation. Br J Cancer 1997; 75: 1410-1416.
11. Breiteneder-Geleff S, Soleiman A, Kowalski H, et al. Angiosarcomas express mixed endothelial phenotypes of blood and lymphatic capillaries: podoplanin as a specific marker for lymphatic endothelium. Am J Pathol 1999; 154: 385-394.
12. Makitie AA, Koivunen P, Keski-Santti H, et al. Oral tongue carcinoma and its treatment in Finland. Eur Arch Otorhinolaryngol 2007; 264: 263-267.
13. Jalkanen S, Bargatze RF, de los Toyos J, Butcher EC,. Lymphocyte recognition of high endothelium: antibodies to distinct epitopes of an 85-95-kD glycoprotein antigen differentially inhibit lymphocyte binding to lymph node, mucosal, or synovial endothelial cells. J Cell Biol 1987; 105: 983-990.
14. Salmi M, Jalkanen S,. A 90-kilodalton endothelial cell molecule mediating lymphocyte binding in humans. Science 1992; 257: 1407-1409.
15. Kokko L-L, Hurme S, Maula S-M, et al. Significance of site-specific prognosis of cancer stem cell marker CD44 in head and neck squamous-cell carcinoma. Oral Oncol 2011; 47: 510-516.
16. Liu J, Jiang G,. CD44 and hematologic malignancies. Cell Mol Immunol 2006; 3: 359-365.
17. Mulder JW, Kruyt PM, Sewnath M, et al. Colorectal cancer prognosis and expression of exon-v6-containing CD44 proteins. Lancet 1994; 344: 1470-1472.
18. Mayer B, Jauch KW, Gunthert U, et al. De-novo expression of CD44 and survival in gastric cancer. Lancet 1993; 342: 1019-1022.
19. Prince ME, Sivanandan R, Kaczorowski A, et al. Identification of a subpopulation of cells with cancer stem cell properties in head and neck squamous cell carcinoma. Proc Natl Acad Sci U S A 2007; 104: 973-978.
20. Silva P, Homer JJ, Slevin NJ, et al. Clinical and biological factors affecting response to radiotherapy in patients with head and neck cancer: a review. Clin Otolaryngol 2007; 32: 337-345.
21. Pugh CW, Ratcliffe PJ,. Regulation of angiogenesis by hypoxia: role of the HIF system. Nat Med 2003; 9: 677-684.
22. Greijer AE, van der Groep P, Kemming D, et al. Up-regulation of gene expression by hypoxia is mediated predominantly by hypoxia-inducible factor 1 (HIF-1). J Pathol 2005; 206: 291-304.
23. Kyzas PA, Geleff S, Batistatou A, Agnantis NJ, Stefanou D,. Evidence for lymphangiogenesis and its prognostic implications in head and neck squamous cell carcinoma. J Pathol 2005; 206: 170-177.
24. Thomas J, Primeaux T,. Is p16 immunohistochemistry a more cost-effective method for identification of human papilloma virus-associated head and neck squamous cell carcinoma? Ann Diagn Pathol 2012; 16: 91-99.
25. Reimers N, Kasper HU, Weissenborn SJ, et al. Combined analysis of HPV-DNA, p16 and EGFR expression to predict prognosis in oropharyngeal cancer. Int J Cancer 2007; 120: 1731-1738.
26. Attner P, NAsman A, Du J, et al. Survival in patients with human papillomavirus positive tonsillar cancer in relation to treatment. Int J Cancer 2012; 131: 1124-1130.
27. Sittel C, Ruiz S, Volling P, et al. Prognostic significance of Ki-67 (MIB1), PCNA and p53 in cancer of the oropharynx and oral cavity. Oral Oncol 1999; 35: 583-589.
28. Hakulinen T, TryggvadOttir L, Gislum M, et al. Trends in the survival of patients diagnosed with cancers of the lip, oral cavity, and pharynx in the Nordic countries 1964-2003 followed up to the end of 2006. Acta Oncol 2010; 49: 561-577.
29. Jones AS, Husband D, Rowley H,. Radical radiotherapy for squamous cell carcinoma of the larynx, oropharynx and hypopharynx: patterns of recurrence, treatment and survival. Clin Otolaryngol Allied Sci 1998; 23: 496-511.
30. Kreimer AR, Clifford GM, Boyle P, Franceschi S,. Human papillomavirus types in head and neck squamous cell carcinomas worldwide: a systematic review. Cancer Epidemiol Biomarkers Prev 2005; 14: 467-475.
31. Chung CH, Ely K, McGavran L, et al. Increased epidermal growth factor receptor gene copy number is associated with poor prognosis in head and neck squamous cell carcinomas. J Clin Oncol 2006; 24: 4170-4176.