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Volumn 63, Issue 9, 2014, Pages 1131-1140

The saturated fatty acid, palmitic acid, induces anxiety-like behavior in mice

Author keywords

Anxiety; Free fatty acid; Palmitic acid

Indexed keywords

5 HYDROXYINDOLEACETIC ACID; DECANOIC ACID; DECANOIC ACID DERIVATIVE; DOPAMINE; INTERLEUKIN 1; INTERLEUKIN 6; MYELOID DIFFERENTIATION FACTOR 88; MYRISTIC ACID; NORADRENALIN; OCTANOIC ACID; PALMITIC ACID; PALMITOLEIC ACID; SATURATED FATTY ACID; SEROTONIN; TOLL LIKE RECEPTOR 4; TUMOR NECROSIS FACTOR ALPHA; VALERIC ACID;

EID: 84906263730     PISSN: 00260495     EISSN: 15328600     Source Type: Journal    
DOI: 10.1016/j.metabol.2014.06.002     Document Type: Article
Times cited : (64)

References (75)
  • 1
    • 72449131377 scopus 로고    scopus 로고
    • The effect of obesity on health outcomes
    • J.B. Dixon The effect of obesity on health outcomes Mol Cell Endocrinol 316 2010 104 108
    • (2010) Mol Cell Endocrinol , vol.316 , pp. 104-108
    • Dixon, J.B.1
  • 2
    • 84878622870 scopus 로고    scopus 로고
    • Early effects of high-fat diet on neurovascular function and focal ischemic brain injury
    • W. Li, R. Prakash, D. Chawla, W. Du, S.P. Didion, and J.A. Filosa et al. Early effects of high-fat diet on neurovascular function and focal ischemic brain injury Am J Physiol Regul Integr 304 2013 R1001 R1008
    • (2013) Am J Physiol Regul Integr , vol.304
    • Li, W.1    Prakash, R.2    Chawla, D.3    Du, W.4    Didion, S.P.5    Filosa, J.A.6
  • 3
    • 84878881481 scopus 로고    scopus 로고
    • Obesity and psychiatric disorders: Commonalities in dysregulated biological pathways and their implications for treatment
    • A.L. Lopresti, and P.D. Drummond Obesity and psychiatric disorders: commonalities in dysregulated biological pathways and their implications for treatment Prog Neuropsychopharmacol Biol Psychiatry 45 2013 92 99
    • (2013) Prog Neuropsychopharmacol Biol Psychiatry , vol.45 , pp. 92-99
    • Lopresti, A.L.1    Drummond, P.D.2
  • 4
    • 84862315447 scopus 로고    scopus 로고
    • A narrative review of physical activity, nutrition, and obesity to cognition and scholastic performance across the human lifespan
    • T.M. Burkhalter, and C.H. Hillman A narrative review of physical activity, nutrition, and obesity to cognition and scholastic performance across the human lifespan Adv Nutr 2 2 2011 201S 206S
    • (2011) Adv Nutr , vol.2 , Issue.2
    • Burkhalter, T.M.1    Hillman, C.H.2
  • 5
    • 77949539959 scopus 로고    scopus 로고
    • The association between obesity and anxiety disorders in the population: A systematic review and meta-analysis
    • G. Gariepy, D. Nitka, and N. Schmitz The association between obesity and anxiety disorders in the population: a systematic review and meta-analysis Int J Obes 34 2010 407 419
    • (2010) Int J Obes , vol.34 , pp. 407-419
    • Gariepy, G.1    Nitka, D.2    Schmitz, N.3
  • 6
    • 0032702731 scopus 로고    scopus 로고
    • Macronutrient balances and obesity: The role of diet and physical activity
    • A. Astrup Macronutrient balances and obesity: the role of diet and physical activity Public Health Nutr 2 1999 341 347
    • (1999) Public Health Nutr , vol.2 , pp. 341-347
    • Astrup, A.1
  • 7
    • 0028898298 scopus 로고
    • Dietary fat and obesity: Evidence from epidemiology
    • L. Lissner, and B.L. Heitmann Dietary fat and obesity: evidence from epidemiology Eur J Clin Nutr 49 2 1995 79 90
    • (1995) Eur J Clin Nutr , vol.49 , Issue.2 , pp. 79-90
    • Lissner, L.1    Heitmann, B.L.2
  • 8
    • 68949089312 scopus 로고    scopus 로고
    • Alzheimer's disease is type 3 diabetes - Evidence reviewed
    • S.M. de la Monte, and J.R. Wands Alzheimer's disease is type 3 diabetes - evidence reviewed J Diabetes Sci Technol 2 6 2008 1101 1113
    • (2008) J Diabetes Sci Technol , vol.2 , Issue.6 , pp. 1101-1113
    • De La Monte, S.M.1    Wands, J.R.2
  • 9
    • 79952483902 scopus 로고    scopus 로고
    • Western diet consumption and cognitive impairment: Links to hippocampal dysfunction and obesity
    • S.E. Kanoski, and T.L. Davidson Western diet consumption and cognitive impairment: links to hippocampal dysfunction and obesity Physiol Behav 103 1 2011 59 68
    • (2011) Physiol Behav , vol.103 , Issue.1 , pp. 59-68
    • Kanoski, S.E.1    Davidson, T.L.2
  • 10
    • 84885844490 scopus 로고    scopus 로고
    • A systematic review of variables associated with the relationship between obesity and depression
    • K. Preiss, L. Brennan, and D. Clarke A systematic review of variables associated with the relationship between obesity and depression Obes Rev 14 11 2013 906 918
    • (2013) Obes Rev , vol.14 , Issue.11 , pp. 906-918
    • Preiss, K.1    Brennan, L.2    Clarke, D.3
  • 11
    • 84884579951 scopus 로고    scopus 로고
    • Inter-relationships among diet, obesity and hippocampal-dependent cognitive function
    • T.L. Davidson, S.L. Hargrave, S.E. Swithers, C.H. Sample, X. Fu, and K.P. Kinzig et al. Inter-relationships among diet, obesity and hippocampal-dependent cognitive function Neuroscience 253 2013 110 122
    • (2013) Neuroscience , vol.253 , pp. 110-122
    • Davidson, T.L.1    Hargrave, S.L.2    Swithers, S.E.3    Sample, C.H.4    Fu, X.5    Kinzig, K.P.6
  • 12
  • 13
    • 79952451443 scopus 로고    scopus 로고
    • Obesity, insulin resistance and free fatty acids
    • G. Boden Obesity, insulin resistance and free fatty acids Curr Opin Endocrinol Diabetes Obes 18 2 2011 139 143
    • (2011) Curr Opin Endocrinol Diabetes Obes , vol.18 , Issue.2 , pp. 139-143
    • Boden, G.1
  • 14
    • 80052961222 scopus 로고    scopus 로고
    • Short-term increase of plasma free fatty acids does not interfere with intrinsic mitochondrial function in healthy young men
    • M. Brands, J. Hoeks, H.P. Sauerwein, M.T. Ackermans, M. Ouwens, and N.M. Lammers et al. Short-term increase of plasma free fatty acids does not interfere with intrinsic mitochondrial function in healthy young men Metabolism 60 10 2011 1398 1405
    • (2011) Metabolism , vol.60 , Issue.10 , pp. 1398-1405
    • Brands, M.1    Hoeks, J.2    Sauerwein, H.P.3    Ackermans, M.T.4    Ouwens, M.5    Lammers, N.M.6
  • 15
    • 84865422248 scopus 로고    scopus 로고
    • From excess adiposity to insulin resistance: The role of free fatty acids
    • C. Capurso, and A. Capurso From excess adiposity to insulin resistance: the role of free fatty acids Vascul Pharmacol 57 2-4 2012 91 97
    • (2012) Vascul Pharmacol , vol.57 , Issue.24 , pp. 91-97
    • Capurso, C.1    Capurso, A.2
  • 16
    • 84872492049 scopus 로고    scopus 로고
    • Molecular mechanisms and the role of saturated fatty acids in the progression of non-alcoholic fatty liver disease
    • A.K. Leamy, R.A. Egnatchik, and J.D. Young Molecular mechanisms and the role of saturated fatty acids in the progression of non-alcoholic fatty liver disease Prog Lipid Res 52 1 2013 165 174
    • (2013) Prog Lipid Res , vol.52 , Issue.1 , pp. 165-174
    • Leamy, A.K.1    Egnatchik, R.A.2    Young, J.D.3
  • 17
    • 84857949744 scopus 로고    scopus 로고
    • Triglyceride, nonesterified fatty acids, and prediabetic neuropathy: Role for oxidative-nitrosative stress
    • S. Lupachyk, P. Watcho, N. Hasanova, U. Julius, and I.G. Obrosova Triglyceride, nonesterified fatty acids, and prediabetic neuropathy: role for oxidative-nitrosative stress Free Radic Biol Med 52 8 2012 1255 1263
    • (2012) Free Radic Biol Med , vol.52 , Issue.8 , pp. 1255-1263
    • Lupachyk, S.1    Watcho, P.2    Hasanova, N.3    Julius, U.4    Obrosova, I.G.5
  • 18
    • 84863636004 scopus 로고    scopus 로고
    • Increasing plasma free fatty acids in healthy subjects induces aortic distensibility changes seen in obesity
    • O.J. Rider, C.J. Holloway, Y. Emmanuel, E. Bloch, K. Clarke, and S. Neubauer Increasing plasma free fatty acids in healthy subjects induces aortic distensibility changes seen in obesity Circ Cardiovasc Imaging 5 3 2012 367 375
    • (2012) Circ Cardiovasc Imaging , vol.5 , Issue.3 , pp. 367-375
    • Rider, O.J.1    Holloway, C.J.2    Emmanuel, Y.3    Bloch, E.4    Clarke, K.5    Neubauer, S.6
  • 19
    • 84888355707 scopus 로고    scopus 로고
    • Serum fatty acids and incidence of ischemic stroke among postmenopausal women
    • S. Yaemsiri, S. Sen, L.F. Tinker, W.R. Robinson, R.W. Evans, and W. Rosamond et al. Serum fatty acids and incidence of ischemic stroke among postmenopausal women Stroke 44 10 2013 2710 2717
    • (2013) Stroke , vol.44 , Issue.10 , pp. 2710-2717
    • Yaemsiri, S.1    Sen, S.2    Tinker, L.F.3    Robinson, W.R.4    Evans, R.W.5    Rosamond, W.6
  • 20
    • 0036065628 scopus 로고    scopus 로고
    • Central administration of oleic acid inhibits glucose production and food intake
    • S. Obici, Z. Feng, K. Morgan, D. Stein, G. Karkanias, and L. Rossetti Central administration of oleic acid inhibits glucose production and food intake Diabetes 51 2 2002 271 275
    • (2002) Diabetes , vol.51 , Issue.2 , pp. 271-275
    • Obici, S.1    Feng, Z.2    Morgan, K.3    Stein, D.4    Karkanias, G.5    Rossetti, L.6
  • 21
    • 34548409654 scopus 로고    scopus 로고
    • Toll-like receptors in the brain and their potential roles in neuropathology
    • P.J. Crack, and P.J. Bray Toll-like receptors in the brain and their potential roles in neuropathology Immunol Cell Biol 85 2007 476 480
    • (2007) Immunol Cell Biol , vol.85 , pp. 476-480
    • Crack, P.J.1    Bray, P.J.2
  • 22
    • 40849126885 scopus 로고    scopus 로고
    • Expression of free fatty acid receptor GPR40 in the neurogenic niche of adult monkey hippocampus
    • D. Ma, L. Lu, N.B. Boneva, S. Warashina, D.B. Kaplamadzhiev, and Y. Mori et al. Expression of free fatty acid receptor GPR40 in the neurogenic niche of adult monkey hippocampus Hippocampus 18 2008 326 333
    • (2008) Hippocampus , vol.18 , pp. 326-333
    • Ma, D.1    Lu, L.2    Boneva, N.B.3    Warashina, S.4    Kaplamadzhiev, D.B.5    Mori, Y.6
  • 23
    • 84655170245 scopus 로고    scopus 로고
    • Involvement of the long-chain fatty acid receptor GPR40 as a novel pain regulatory system
    • K. Nakamoto, T. Nishinaka, K. Matsumoto, F. Kasuya, M. Mankura, and Y. Koyama et al. Involvement of the long-chain fatty acid receptor GPR40 as a novel pain regulatory system Brain Res 1432 2012 74 83
    • (2012) Brain Res , vol.1432 , pp. 74-83
    • Nakamoto, K.1    Nishinaka, T.2    Matsumoto, K.3    Kasuya, F.4    Mankura, M.5    Koyama, Y.6
  • 24
    • 42649089040 scopus 로고    scopus 로고
    • The descriptive epidemiology of commonly occurring mental disorders in the United States
    • R.C. Kessler, and P.S. Wang The descriptive epidemiology of commonly occurring mental disorders in the United States Annu Rev Public Health 29 2008 115 129
    • (2008) Annu Rev Public Health , vol.29 , pp. 115-129
    • Kessler, R.C.1    Wang, P.S.2
  • 26
    • 42149092160 scopus 로고    scopus 로고
    • Overweight and obesity are associated with psychiatric disorders: Results from the National Epidemiologic Survey on alcohol and related conditions
    • N.M. Petry, D. Barry, R.H. Pietrzak, and J.A. Wagner Overweight and obesity are associated with psychiatric disorders: results from the National Epidemiologic Survey on alcohol and related conditions Psychosom Med 70 3 2008 288 297
    • (2008) Psychosom Med , vol.70 , Issue.3 , pp. 288-297
    • Petry, N.M.1    Barry, D.2    Pietrzak, R.H.3    Wagner, J.A.4
  • 27
    • 0023680345 scopus 로고
    • Caffeine reduction as an adjunct to anxiety management
    • G.A. Smith Caffeine reduction as an adjunct to anxiety management Br J Clin Psychol 27 1988 265 266
    • (1988) Br J Clin Psychol , vol.27 , pp. 265-266
    • Smith, G.A.1
  • 28
    • 0033964079 scopus 로고    scopus 로고
    • The relationship between anxiety disorders and alcohol use disorders: A review of major perspectives and findings
    • M.G. Kushner, K. Abrams, and C. Borchardt The relationship between anxiety disorders and alcohol use disorders: a review of major perspectives and findings Clin Psychol Rev 20 2 2000 149 171
    • (2000) Clin Psychol Rev , vol.20 , Issue.2 , pp. 149-171
    • Kushner, M.G.1    Abrams, K.2    Borchardt, C.3
  • 29
    • 84875848580 scopus 로고    scopus 로고
    • Substituting dietary monounsaturated fat for saturated fat is associated with increased daily physical activity and resting energy expenditure and with changes in mood
    • C.L. Kien, J.Y. Bunn, C.L. Tompkins, J.A. Dumas, K.I. Crain, and D.B. Ebenstein et al. Substituting dietary monounsaturated fat for saturated fat is associated with increased daily physical activity and resting energy expenditure and with changes in mood Am J Clin Nutr 97 4 2013 689 697
    • (2013) Am J Clin Nutr , vol.97 , Issue.4 , pp. 689-697
    • Kien, C.L.1    Bunn, J.Y.2    Tompkins, C.L.3    Dumas, J.A.4    Crain, K.I.5    Ebenstein, D.B.6
  • 30
    • 0037312745 scopus 로고    scopus 로고
    • Dietary fat, fatty acid composition in plasma and the metabolic syndrome
    • B. Vessby Dietary fat, fatty acid composition in plasma and the metabolic syndrome Curr Opin Lipidol 14 1 2003 15 19
    • (2003) Curr Opin Lipidol , vol.14 , Issue.1 , pp. 15-19
    • Vessby, B.1
  • 31
    • 84892496890 scopus 로고    scopus 로고
    • Plasma fatty acid composition, estimated desaturase activities, and their relation with the metabolic syndrome in a population at high risk of cardiovascular disease
    • J. Mayneris-Perxachs, M. Guerendiain, A.I. Castellote, R. Estruch, M.I. Covas, and M. Fitó et al. Plasma fatty acid composition, estimated desaturase activities, and their relation with the metabolic syndrome in a population at high risk of cardiovascular disease Clin Nutr 33 1 2013 90 97
    • (2013) Clin Nutr , vol.33 , Issue.1 , pp. 90-97
    • Mayneris-Perxachs, J.1    Guerendiain, M.2    Castellote, A.I.3    Estruch, R.4    Covas, M.I.5    Fitó, M.6
  • 32
    • 85003272707 scopus 로고    scopus 로고
    • Mouse short- and long-term locomotor activity analyzed by video tracking software
    • J.M. York, N.A. Blevins, L.K. McNeil, and G.G. Freund Mouse short- and long-term locomotor activity analyzed by video tracking software J Vis Exp 76 2013 e50252
    • (2013) J Vis Exp , vol.76 , pp. 50252
    • York, J.M.1    Blevins, N.A.2    McNeil, L.K.3    Freund, G.G.4
  • 33
    • 84867011723 scopus 로고    scopus 로고
    • Mouse testing methods in psychoneuroimmunology: An overview of how to measure sickness, depressive/anxietal, cognitive, and physical activity behaviors
    • J.M. York, N.A. Blevins, T. Baynard, and G.G. Freund Mouse testing methods in psychoneuroimmunology: an overview of how to measure sickness, depressive/anxietal, cognitive, and physical activity behaviors Methods Mol Biol 934 2012 243 276
    • (2012) Methods Mol Biol , vol.934 , pp. 243-276
    • York, J.M.1    Blevins, N.A.2    Baynard, T.3    Freund, G.G.4
  • 34
    • 84856098450 scopus 로고    scopus 로고
    • Acute hypoglycemia causes depressive-like behaviors in mice
    • M.J. Park, S.W. Yoo, B.S. Choe, R. Dantzer, and G.G. Freund Acute hypoglycemia causes depressive-like behaviors in mice Metabolism 61 2 2011 229 236
    • (2011) Metabolism , vol.61 , Issue.2 , pp. 229-236
    • Park, M.J.1    Yoo, S.W.2    Choe, B.S.3    Dantzer, R.4    Freund, G.G.5
  • 35
    • 84866983407 scopus 로고    scopus 로고
    • Hypoxia/reoxygenation impairs memory formation via adenosine-dependent activation of caspase 1
    • G.S. Chiu, D. Chatterjee, P.T. Darmody, J.P. Walsh, D.D. Meling, and R.W. Johnson et al. Hypoxia/reoxygenation impairs memory formation via adenosine-dependent activation of caspase 1 J Neurosci 32 40 2012 13945 13955
    • (2012) J Neurosci , vol.32 , Issue.40 , pp. 13945-13955
    • Chiu, G.S.1    Chatterjee, D.2    Darmody, P.T.3    Walsh, J.P.4    Meling, D.D.5    Johnson, R.W.6
  • 36
    • 65349135346 scopus 로고    scopus 로고
    • Lipopolysaccharide-induced depressive-like behavior is mediated by indoleamine 2,3-dioxygenase activation in mice
    • J.C. O'Connor, M.A. Lawson, C. Andre, M. Moreau, J. Lestage, and N. Castanon et al. Lipopolysaccharide-induced depressive-like behavior is mediated by indoleamine 2,3-dioxygenase activation in mice Mol Psychiatry 14 5 2009 511 522
    • (2009) Mol Psychiatry , vol.14 , Issue.5 , pp. 511-522
    • O'Connor, J.C.1    Lawson, M.A.2    Andre, C.3    Moreau, M.4    Lestage, J.5    Castanon, N.6
  • 37
    • 59749096280 scopus 로고    scopus 로고
    • Dietary interventions for metabolic syndrome
    • C.L. Kien Dietary interventions for metabolic syndrome Curr Diab Rep 9 1 2009 43 50
    • (2009) Curr Diab Rep , vol.9 , Issue.1 , pp. 43-50
    • Kien, C.L.1
  • 38
    • 84875268729 scopus 로고    scopus 로고
    • Associations of depressive symptoms with serum proportions of palmitic and arachidonic acids, and α-tocopherol effects among male population - A preliminary study
    • H. Tsuboi, M. Watanabe, F. Kobayashi, K. Kimura, and N. Kinae Associations of depressive symptoms with serum proportions of palmitic and arachidonic acids, and α-tocopherol effects among male population - a preliminary study Clin Nutr 32 2 2013 289 293
    • (2013) Clin Nutr , vol.32 , Issue.2 , pp. 289-293
    • Tsuboi, H.1    Watanabe, M.2    Kobayashi, F.3    Kimura, K.4    Kinae, N.5
  • 39
    • 79955038882 scopus 로고    scopus 로고
    • Fatty acid-induced NLRP3-ASC inflammasome activation interferes with insulin signaling
    • H. Wen, D. Gris, Y. Lei, S. Jha, L. Zhang, and M. Huang et al. Fatty acid-induced NLRP3-ASC inflammasome activation interferes with insulin signaling Nat Immunol 12 5 2011 408 415
    • (2011) Nat Immunol , vol.12 , Issue.5 , pp. 408-415
    • Wen, H.1    Gris, D.2    Lei, Y.3    Jha, S.4    Zhang, L.5    Huang, M.6
  • 40
    • 84859449180 scopus 로고    scopus 로고
    • Saturated fatty acid and TLR signaling link β cell dysfunction and islet inflammation
    • K. Eguchi, I. Manabe, Y. Oishi-Tanaka, M. Ohsugi, N. Kono, and F. Ogata et al. Saturated fatty acid and TLR signaling link β cell dysfunction and islet inflammation Cell Metab 15 4 2012 518 533
    • (2012) Cell Metab , vol.15 , Issue.4 , pp. 518-533
    • Eguchi, K.1    Manabe, I.2    Oishi-Tanaka, Y.3    Ohsugi, M.4    Kono, N.5    Ogata, F.6
  • 42
    • 37249094173 scopus 로고    scopus 로고
    • From inflammation to sickness and depression: When the immune system subjugates the brain
    • R. Dantzer, J.C. O'Connor, G.G. Freund, R.W. Johnson, and K.W. Kelley From inflammation to sickness and depression: when the immune system subjugates the brain Nat Rev Neurosci 9 1 2008 46 56
    • (2008) Nat Rev Neurosci , vol.9 , Issue.1 , pp. 46-56
    • Dantzer, R.1    O'Connor, J.C.2    Freund, G.G.3    Johnson, R.W.4    Kelley, K.W.5
  • 43
    • 84862812857 scopus 로고    scopus 로고
    • Saturated long-chain fatty acids activate inflammatory signaling in astrocytes
    • S. Gupta, A.G. Knight, S. Gupta, J.N. Keller, and A.J. Bruce-Keller Saturated long-chain fatty acids activate inflammatory signaling in astrocytes J Neurochem 120 6 2012 1060 1071
    • (2012) J Neurochem , vol.120 , Issue.6 , pp. 1060-1071
    • Gupta, S.1    Knight, A.G.2    Gupta, S.3    Keller, J.N.4    Bruce-Keller, A.J.5
  • 44
    • 84885950294 scopus 로고    scopus 로고
    • Exposure to the saturated free fatty acid palmitate alters BV-2 microglia inflammatory response
    • L.M. Tracy, F. Bergqvist, E.V. Ivanova, K.T. Jacobsen, and K. Iverfeldt Exposure to the saturated free fatty acid palmitate alters BV-2 microglia inflammatory response J Mol Neurosci 51 3 2013 805 812
    • (2013) J Mol Neurosci , vol.51 , Issue.3 , pp. 805-812
    • Tracy, L.M.1    Bergqvist, F.2    Ivanova, E.V.3    Jacobsen, K.T.4    Iverfeldt, K.5
  • 45
    • 84872400077 scopus 로고    scopus 로고
    • Palmitic acid increases apoptosis of neural stem cells via activating c-Jun N-terminal kinase
    • Q. Yuan, S. Zhao, F. Wang, H. Zhang, Z. Chen, and J. Wang et al. Palmitic acid increases apoptosis of neural stem cells via activating c-Jun N-terminal kinase Stem Cell Res 10 2 2013 257 266
    • (2013) Stem Cell Res , vol.10 , Issue.2 , pp. 257-266
    • Yuan, Q.1    Zhao, S.2    Wang, F.3    Zhang, H.4    Chen, Z.5    Wang, J.6
  • 46
    • 0035907302 scopus 로고    scopus 로고
    • Saturated fatty acids, but not unsaturated fatty acids, induce the expression of cyclooxygenase-2 mediated through Toll-like receptor 4
    • J.Y. Lee, K.H. Sohn, S.H. Rhee, and D. Hwang Saturated fatty acids, but not unsaturated fatty acids, induce the expression of cyclooxygenase-2 mediated through Toll-like receptor 4 J Biol Chem 276 20 2001 16683 16689
    • (2001) J Biol Chem , vol.276 , Issue.20 , pp. 16683-16689
    • Lee, J.Y.1    Sohn, K.H.2    Rhee, S.H.3    Hwang, D.4
  • 47
    • 84897018309 scopus 로고    scopus 로고
    • Toll-like receptor 2/4 links to free fatty acid-induced inflammation and β-cell dysfunction
    • J. Yin, Y. Peng, J. Wu, Y. Wang, and L. Yao Toll-like receptor 2/4 links to free fatty acid-induced inflammation and β-cell dysfunction J Leukoc Biol 95 1 2013 47 52
    • (2013) J Leukoc Biol , vol.95 , Issue.1 , pp. 47-52
    • Yin, J.1    Peng, Y.2    Wu, J.3    Wang, Y.4    Yao, L.5
  • 48
    • 80054864952 scopus 로고    scopus 로고
    • Macrophages make me sick: How macrophage activation states influence sickness behavior
    • M.L. Moon, L.K. McNeil, and G.G. Freund Macrophages make me sick: how macrophage activation states influence sickness behavior Psychoneuroendocrinology 36 10 2011 1431 1440
    • (2011) Psychoneuroendocrinology , vol.36 , Issue.10 , pp. 1431-1440
    • Moon, M.L.1    McNeil, L.K.2    Freund, G.G.3
  • 49
    • 58149095589 scopus 로고    scopus 로고
    • International Union of Pharmacology. LXXI. Free fatty acid receptors FFA1, -2, and -3: Pharmacology and pathophysiological functions
    • L.A. Stoddart, N.J. Smith, and G. Milligan International Union of Pharmacology. LXXI. Free fatty acid receptors FFA1, -2, and -3: pharmacology and pathophysiological functions Pharmacol Rev 60 4 2008 405 417
    • (2008) Pharmacol Rev , vol.60 , Issue.4 , pp. 405-417
    • Stoddart, L.A.1    Smith, N.J.2    Milligan, G.3
  • 50
    • 0037838892 scopus 로고    scopus 로고
    • The orphan G protein-coupled receptor GPR40 is activated by medium and long chain fatty acids
    • C.P. Briscoe, M. Tadayyon, J.L. Andrews, W.G. Benson, J.K. Chambers, and M.M. Eilert et al. The orphan G protein-coupled receptor GPR40 is activated by medium and long chain fatty acids J Biol Chem 278 13 2003 11303 11311
    • (2003) J Biol Chem , vol.278 , Issue.13 , pp. 11303-11311
    • Briscoe, C.P.1    Tadayyon, M.2    Andrews, J.L.3    Benson, W.G.4    Chambers, J.K.5    Eilert, M.M.6
  • 52
    • 79954598480 scopus 로고    scopus 로고
    • Short-term consumption of a high-fat diet impairs whole-body efficiency and cognitive function in sedentary men
    • L.M. Edwards, A.J. Murray, C.J. Holloway, E.E. Carter, G.J. Kemp, and I. Codreanu et al. Short-term consumption of a high-fat diet impairs whole-body efficiency and cognitive function in sedentary men FASEB J 25 3 2011 1088 1096
    • (2011) FASEB J , vol.25 , Issue.3 , pp. 1088-1096
    • Edwards, L.M.1    Murray, A.J.2    Holloway, C.J.3    Carter, E.E.4    Kemp, G.J.5    Codreanu, I.6
  • 53
    • 72749106820 scopus 로고    scopus 로고
    • Deterioration of physical performance and cognitive function in rats with short-term high-fat feeding
    • A.J. Murray, N.S. Knight, L.E. Cochlin, S. McAleese, R.M.J. Deacon, and J.N.P. Rawlins et al. Deterioration of physical performance and cognitive function in rats with short-term high-fat feeding FASEB J 23 12 2009 4353 4360
    • (2009) FASEB J , vol.23 , Issue.12 , pp. 4353-4360
    • Murray, A.J.1    Knight, N.S.2    Cochlin, L.E.3    McAleese, S.4    Deacon, R.M.J.5    Rawlins, J.N.P.6
  • 55
    • 84883253824 scopus 로고    scopus 로고
    • Prevalence and features of generalized anxiety disorder in Department of Veteran Affairs primary care settings
    • M.E. Milanak, D.F. Gros, K.M. Magruder, O. Brawman-Mintzer, and B.C. Frueh Prevalence and features of generalized anxiety disorder in Department of Veteran Affairs primary care settings Psychiatry Res 209 2 2013 173 179
    • (2013) Psychiatry Res , vol.209 , Issue.2 , pp. 173-179
    • Milanak, M.E.1    Gros, D.F.2    Magruder, K.M.3    Brawman-Mintzer, O.4    Frueh, B.C.5
  • 56
    • 0016691920 scopus 로고
    • Fatty acid binding to plasma albumin
    • A.A. Spector Fatty acid binding to plasma albumin J Lipid Res 16 3 1975 165 179
    • (1975) J Lipid Res , vol.16 , Issue.3 , pp. 165-179
    • Spector, A.A.1
  • 57
    • 33947358098 scopus 로고    scopus 로고
    • Uncovering the pharmacology of the G protein-coupled receptor GPR40: High apparent constitutive activity in guanosine 5′-O-(3-[35S]thio) triphosphate binding studies reflects binding of an endogenous agonist
    • L.A. Stoddart, A.J. Brown, and G. Milligan Uncovering the pharmacology of the G protein-coupled receptor GPR40: high apparent constitutive activity in guanosine 5′-O-(3-[35S]thio)triphosphate binding studies reflects binding of an endogenous agonist Mol Pharmacol 71 4 2007 994 1005
    • (2007) Mol Pharmacol , vol.71 , Issue.4 , pp. 994-1005
    • Stoddart, L.A.1    Brown, A.J.2    Milligan, G.3
  • 58
    • 33344461956 scopus 로고    scopus 로고
    • Social anxiety, alcohol expectancies, and self-efficacy as predictors of heavy drinking in college students
    • D.M. Gilles, C.L. Turk, and D.M. Fresco Social anxiety, alcohol expectancies, and self-efficacy as predictors of heavy drinking in college students Addict Behav 31 3 2006 388 398
    • (2006) Addict Behav , vol.31 , Issue.3 , pp. 388-398
    • Gilles, D.M.1    Turk, C.L.2    Fresco, D.M.3
  • 59
    • 77049299397 scopus 로고
    • A relation between non-esterified fatty acids in plasma and the metabolism of glucose
    • V.P. Dole A relation between non-esterified fatty acids in plasma and the metabolism of glucose J Clin Invest 35 2 1956 150 154
    • (1956) J Clin Invest , vol.35 , Issue.2 , pp. 150-154
    • Dole, V.P.1
  • 60
    • 84883885115 scopus 로고    scopus 로고
    • Serotonin and beyond: Therapeutics for major depression
    • P. Blier, and M. El Mansari Serotonin and beyond: therapeutics for major depression Philos Trans R Soc Lond B Biol Sci 368 1615 2013 20120536
    • (2013) Philos Trans R Soc Lond B Biol Sci , vol.368 , Issue.1615 , pp. 20120536
    • Blier, P.1    El Mansari, M.2
  • 61
    • 84890426529 scopus 로고    scopus 로고
    • The 5-HTTLPR polymorphism and posttraumatic stress disorder: A meta-analysis
    • F. Gressier, R. Calati, M. Balestri, A. Marsano, S. Alberti, and N. Antypa et al. The 5-HTTLPR polymorphism and posttraumatic stress disorder: a meta-analysis J Trauma Stress 26 6 2013 645 653
    • (2013) J Trauma Stress , vol.26 , Issue.6 , pp. 645-653
    • Gressier, F.1    Calati, R.2    Balestri, M.3    Marsano, A.4    Alberti, S.5    Antypa, N.6
  • 62
    • 80155157843 scopus 로고    scopus 로고
    • Molecular mechanisms of fear learning and memory
    • J.P. Johansen, C.K. Cain, L.E. Ostroff, and J.E. LeDoux Molecular mechanisms of fear learning and memory Cell 147 3 2011 509 524
    • (2011) Cell , vol.147 , Issue.3 , pp. 509-524
    • Johansen, J.P.1    Cain, C.K.2    Ostroff, L.E.3    Ledoux, J.E.4
  • 63
    • 84888630059 scopus 로고    scopus 로고
    • Neuropathogenesis of delirium: Review of current etiologic theories and common pathways
    • J.R. Maldonado Neuropathogenesis of delirium: review of current etiologic theories and common pathways Am J Geriatr Psychiatry 21 12 2013 1190 1222
    • (2013) Am J Geriatr Psychiatry , vol.21 , Issue.12 , pp. 1190-1222
    • Maldonado, J.R.1
  • 64
    • 84874542894 scopus 로고    scopus 로고
    • Anxiety and affective disorder comorbidity related to serotonin and other neurotransmitter systems: Obsessive-compulsive disorder as an example of overlapping clinical and genetic heterogeneity
    • D.L. Murphy, P.R. Moya, M.A. Fox, L.M. Rubenstein, J.R. Wendland, and K.R. Timpano Anxiety and affective disorder comorbidity related to serotonin and other neurotransmitter systems: obsessive-compulsive disorder as an example of overlapping clinical and genetic heterogeneity Philos Trans R Soc Lond B Biol Sci 368 1615 2013 20120435
    • (2013) Philos Trans R Soc Lond B Biol Sci , vol.368 , Issue.1615 , pp. 20120435
    • Murphy, D.L.1    Moya, P.R.2    Fox, M.A.3    Rubenstein, L.M.4    Wendland, J.R.5    Timpano, K.R.6
  • 65
    • 79251598360 scopus 로고    scopus 로고
    • Central dopaminergic circuitry controlling food intake and reward: Implications for the regulation of obesity
    • Z. Vucetic, and T.M. Reyes Central dopaminergic circuitry controlling food intake and reward: implications for the regulation of obesity Wiley Interdiscip Rev Syst Biol Med 2 5 2010 577 593
    • (2010) Wiley Interdiscip Rev Syst Biol Med , vol.2 , Issue.5 , pp. 577-593
    • Vucetic, Z.1    Reyes, T.M.2
  • 66
    • 0033360315 scopus 로고    scopus 로고
    • Amygdala activity related to enhanced memory for pleasant and aversive stimuli
    • S.B. Hamann, T.D. Ely, S.T. Grafton, and C.D. Kilts Amygdala activity related to enhanced memory for pleasant and aversive stimuli Nat Neurosci 2 3 1999 289 293
    • (1999) Nat Neurosci , vol.2 , Issue.3 , pp. 289-293
    • Hamann, S.B.1    Ely, T.D.2    Grafton, S.T.3    Kilts, C.D.4
  • 67
    • 0026535166 scopus 로고
    • The role of the amygdala in fear and anxiety
    • M. Davis The role of the amygdala in fear and anxiety Annu Rev Neurosci 15 1992 353 375
    • (1992) Annu Rev Neurosci , vol.15 , pp. 353-375
    • Davis, M.1
  • 68
    • 84892582481 scopus 로고    scopus 로고
    • Neuropharmacologic studies on the brain serotonin 1A receptor using the selective agonist osemozotan
    • T. Matsuda Neuropharmacologic studies on the brain serotonin 1A receptor using the selective agonist osemozotan Biol Pharm Bull 36 12 2013 1871 1882
    • (2013) Biol Pharm Bull , vol.36 , Issue.12 , pp. 1871-1882
    • Matsuda, T.1
  • 69
    • 77950021602 scopus 로고    scopus 로고
    • Urocortin-1 and -2 double-deficient mice show robust anxiolytic phenotype and modified serotonergic activity in anxiety circuits
    • [339]
    • A. Neufeld-Cohen, A.K. Evans, D. Getselter, A. Spyroglou, A. Hill, and S. Gil et al. Urocortin-1 and -2 double-deficient mice show robust anxiolytic phenotype and modified serotonergic activity in anxiety circuits Mol Psychiatry 15 4 2010 426 441 [339]
    • (2010) Mol Psychiatry , vol.15 , Issue.4 , pp. 426-441
    • Neufeld-Cohen, A.1    Evans, A.K.2    Getselter, D.3    Spyroglou, A.4    Hill, A.5    Gil, S.6
  • 70
    • 84892673575 scopus 로고    scopus 로고
    • Palmitate-induced activation of mitochondrial metabolism promotes oxidative stress and apoptosis in H4IIEC3 rat hepatocytes
    • R.A. Egnatchik, A.K. Leamy, Y. Noguchi, M. Shiota, and J.D. Young Palmitate-induced activation of mitochondrial metabolism promotes oxidative stress and apoptosis in H4IIEC3 rat hepatocytes Metabolism 63 2 2014 283 295
    • (2014) Metabolism , vol.63 , Issue.2 , pp. 283-295
    • Egnatchik, R.A.1    Leamy, A.K.2    Noguchi, Y.3    Shiota, M.4    Young, J.D.5
  • 71
    • 84901245909 scopus 로고    scopus 로고
    • Glucagon-like peptide-1 production in the GLUTag cell line is impaired by free fatty acids via endoplasmic reticulum stress
    • H. Havashi, R. Yamada, S.S. Das, T. Sato, A. Takahashi, and M. Hiratsuka et al. Glucagon-like peptide-1 production in the GLUTag cell line is impaired by free fatty acids via endoplasmic reticulum stress Metabolism 63 6 2014 800 811
    • (2014) Metabolism , vol.63 , Issue.6 , pp. 800-811
    • Havashi, H.1    Yamada, R.2    Das, S.S.3    Sato, T.4    Takahashi, A.5    Hiratsuka, M.6
  • 72
    • 84894033378 scopus 로고    scopus 로고
    • The effect of FFAR1 on pioglitazone-mediated attenuation of palmitic acid-induced oxidative stress and apoptosis in βtC6 cells
    • X. Shen, L. Yang, S. Yan, W. Wei, L. Liang, and H. Zheng et al. The effect of FFAR1 on pioglitazone-mediated attenuation of palmitic acid-induced oxidative stress and apoptosis in βTC6 cells Metabolism 63 3 2014 335 351
    • (2014) Metabolism , vol.63 , Issue.3 , pp. 335-351
    • Shen, X.1    Yang, L.2    Yan, S.3    Wei, W.4    Liang, L.5    Zheng, H.6
  • 73
    • 62749104401 scopus 로고    scopus 로고
    • Endoplasmic reticulum stress: Another link between obesity and insulin resistance/inflammation?
    • G. Boden Endoplasmic reticulum stress: another link between obesity and insulin resistance/inflammation? Diabetes 58 3 2009 518 519
    • (2009) Diabetes , vol.58 , Issue.3 , pp. 518-519
    • Boden, G.1
  • 74
    • 84899419103 scopus 로고    scopus 로고
    • Hypothalamic endoplasmic reticulum stress and insulin resistance in offspring of mice dams fed high-fat diet during pregnancy and lactation
    • A.M. Melo, R.O. Benatti, L.M. Ignacio-Souza, C. Okino, A.S. Torsoni, and M. Milanski et al. Hypothalamic endoplasmic reticulum stress and insulin resistance in offspring of mice dams fed high-fat diet during pregnancy and lactation Metabolism 63 5 2014 682 692
    • (2014) Metabolism , vol.63 , Issue.5 , pp. 682-692
    • Melo, A.M.1    Benatti, R.O.2    Ignacio-Souza, L.M.3    Okino, C.4    Torsoni, A.S.5    Milanski, M.6
  • 75
    • 84902343044 scopus 로고    scopus 로고
    • The unfolded protein response governs integrity of the haematopoietic stem-cell pool during stress
    • 10.1038/nature13228 [Epub ahead of print]
    • P. van Galen, A. Kreso, N. Mbong, D.G. Kent, T. Fitzmaurice, and J.E. Chambers et al. The unfolded protein response governs integrity of the haematopoietic stem-cell pool during stress Nature 2014 10.1038/nature13228 [Epub ahead of print]
    • (2014) Nature
    • Van Galen, P.1    Kreso, A.2    Mbong, N.3    Kent, D.G.4    Fitzmaurice, T.5    Chambers, J.E.6


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