The effect of ffar1 on pioglitazone-mediated attenuation of palmitic acid-induced oxidative stress and apoptosis in βtc6 cells

Metabolism: Clinical and Experimental

Volumn 63, Issue 3, 2014, Pages 335-351

  Shen, Ximei ^a   Yang, Liyong ^a   Yan, Sunjie ^a   Wei, Wenfeng ^a   Liang, Liyu ^a   Zheng, Huanhuan ^a   Cai, Xiuhui ^a  

^a FUJIAN MEDICAL UNIVERSITY   (China)

Author keywords

cell; Free fatty acid receptor 1; Lipoapoptosis; Oxidative stress; Pioglitazone

Indexed keywords

FREE FATTY ACID RECEPTOR 1; LIPOAPOPTOSIS; OXIDATIVE STRESS; PIOGLITAZONE; Β CELL;

ANIMALS; APOPTOSIS; CELL LINE; DOWN-REGULATION; FATTY ACIDS, NONESTERIFIED; HYDROGEN PEROXIDE; INSULIN-SECRETING CELLS; MICE; OXIDATIVE STRESS; PALMITIC ACID; RECEPTORS, G-PROTEIN-COUPLED; SIGNAL TRANSDUCTION; THIAZOLIDINEDIONES; UP-REGULATION;

EID: 84894033378     PISSN: 00260495     EISSN: 15328600     Source Type: Journal    
DOI: 10.1016/j.metabol.2013.11.003     Document Type: Article

References (30)

1. H.Q. Li, B.P. Wang, X.L. Deng, X.L. Deng, J.Y. Zhang, Y.B Wang, and J. Zheng et al. Insulin improves β-cell function in glucose-intolerant rat models induced by feeding a high-fat diet Metabolism 60 11 Nov 2011 1566 1574
2. Y. Itoh, Y. Kawata, M. Harada, M. Kobayashi, R. Fujii, and S. Fukusumi et al. GPR40-induced insulin secretion by the novel agonist TAK-875: first clinical findings in patients with type 2 diabetes Diabetes Obes Metab 14 3 2012 271 278
3. J. Wu, P. Sun, X. Zhang, H. Liu, H. Jiang, and W. Zhu et al. Inhibition of GPR40 protects MIN6 β cells from palmitate-induced ER stress and apoptosis J Cell Biochem 113 4 Apr 2012 1152 1158
4. K. Matsuda-Nagasumi, R. Takami-Esaki, K. Iwachidow, Y. Yasuhara, H. Tanaka, and K. Ogi et al. Lack of GPR40/FFAR1 does not induce diabetes even under insulin resistance condition Diabetes Obes Metab 15 6 Jun 2013 538 545
5. R. Wagner, G. Kaiser, F. Gerst, E. Christiansen, M.E. Due-Hansen, and M. Grundmann et al. Reevaluation of fatty acid receptor 1 as a drug target for the stimulation of insulin secretion in humans Diabetes 62 6 Jun 2013 2106 2111
6. P. Wu, L. Yang, and X. Shen The relationship between GPR40 and lipotoxicity of the pancreatic β-cells as well as the effect of pioglitazone Biochem Biophys Res Commun 403 1 2010 36 39
7. T. Araki, M. Hirayama, S. Hiroi, and K. Kaku Free fatty acids regulate insulin secretion from pancreatic beta cells through GPR40 Nature 422 6928 2003 173 176
8. K. Kaku, T. Araki, and R. Yoshinaka Randomized, double-blind, dose-ranging study of TAK-875, a novel GPR40 agonist, in Japanese patients with inadequately controlled type 2 diabetes Diabetes Care 36 2 Feb 2013 245 250
9. E. Leifke, H. Naik, J. Wu, P. Viswanathan, D. Demanno, and M. Kipnes et al. A multiple-ascending-dose study to evaluate safety, pharmacokinetics, and pharmacodynamics of a novel GPR40 agonist, TAK-875, in subjects with type 2 diabetes Clin Pharmacol Ther 92 1 Jul 2012 29 39
10. T. Hara, A. Hirasawa, A. Ichimura, I. Kimura, and G. Tsujimoto Free fatty acid receptors FFAR1 and GPR120 as novel therapeutic targets for metabolic disorders J Pharm Sci 100 9 2011 3594 3601
11. D.L. Chen, J.N. Xiang, and L.Y. Yang Role of ERp46 in β-cell lipoapoptosis through endoplasmic reticulum stress pathway as well as the protective effect of exendin-4 Biochem Biophys Res Commun 426 2012 324 329
12. A.M. Nivala, L. Reese, M. Frye, C.L. Gentile, and M.J. Pagliassotti Fatty acid-mediated endoplasmic reticulum stress in vivo: differential response to the infusion of soybean and lard oil in rats Metabolism 62 5 May 2013 753 760
13. J.N. Xiang, D.L. Chen, and L.Y. Yang Effect of PANDER in βTC6-cell lipoapoptosis and the protective role of exendin-4 Biochem Biophys Res Commun 421 2012 701 706
14. M. Alba, B. Ahrén, S.E. Inzucchi, Y. Guan, M. Mallick, and L. Xu et al. Sitagliptin and pioglitazone provide complementary effects on postprandial glucose and pancreatic islet cell function Diabetes Obes Metab Jun 19 2013 10.1111/dom.12145 [Epub ahead of print]
15. H. Yin, S.Y. Park, X.J. Wang, R. Misawa, E.J. Grossman, and J. Tao et al. Enhancing pancreatic beta-cell regeneration in vivo with pioglitazone and alogliptin PLoS One 8 6 Jun 6 2013 e65777
16. Y. Li, X. Zhang, and N. Tong Pioglitazone ameliorates palmitate induced impairment of mitochondrial morphology and function and restores insulin level in beta cells Pharmazie 68 4 Apr 2013 270 273
17. H.S. Kim, Y.C. Hwang, S.H. Koo, K.S. Park, M.S. Lee, and K.W. Kim et al. PPAR-γ activation increases insulin secretion through the up-regulation of the free fatty acid receptor GPR40 in pancreatic β-cells PLoS One 8 1 2013 e50128
18. S. Del Guerra, M. Bugliani, V. D'Aleo, S. Del Prato, U. Boggi, and F. Mosca et al. G-protein-coupled receptor 40 (GPR40) expression and its regulation in human pancreatic islets: the role of type 2 diabetes and fatty acids Nutr Metab Cardiovasc Dis 20 1 2010 22 25
19. Y. Tuo, D.D. Feng, D.F. Wang, J. Sun, S.B. Li, and C. Chen Long-term in vitro treatment of INS-1 rat pancreatic β-cells by unsaturated free fatty acids protects cells from gluco- and lipo-toxicities through activation of GPR40 receptors Clin Exp Pharmacol Physiol 39 5 May 2012 423 428
20. L.S. Doshi, M.K. Brahma, S.G. Sayyed, A.V. Dixit, P.G. Chandak, and V. Pamidiboina et al. Acute administration of GPR40 receptor agonist potentiates glucose-stimulated insulin secretion in vivo in the rat Metabolism 58 3 Mar 2009 333 343
21. J. Luo, K. Nguyen, M. Chen, T. Tran, J. Hao, and B. Tian et al. Evaluating insulin secretagogues in a humanized mouse model with functional human islets Metabolism 62 1 Jan 2013 90 99
22. G.G. Korkmaz, E. AltInoglu, S. Civelek, V. Sozer, F. Sozer, and O. Tabak et al. The association of oxidative stress markers with conventional risk factors in the metabolic syndrome Metabolism 62 6 Jun 2013 828 835
23. M.F. Graciano, L.R. Santos, R. Curi, and A.R. Carpinelli NAD(P)H oxidase participates in the palmitate-induced superoxide production and insulin secretion by rat pancreatic islets J Cell Physiol 226 4 2011 1110 1117
24. A. Martín, J.V. Pérez-Girón, R. Hernanz, R. Palacios, A.M. Briones, and A. Fortuño et al. Peroxisome proliferator-activated receptor-γ activation reduces cyclooxygenase-2 expression in vascular smooth muscle cells from hypertensive rats by interfering with oxidative stress J Hypertens 30 2 2012 315 326
25. B. Reel, M. Guzeloglu, A. Bagriyanik, S. Atmaca, K. Aykut, and G. Albayrak et al. The effects of PPAR-γ agonist pioglitazone on renal ischemia/reperfusion injury in rats J Surg Res 182 1 Jun 1 2013 176 184
26. Y.J. Zhou, Y.L. Song, H. Zhou, and Y. Li Linoleic acid activates GPR40/FFA1 and phospholipase C to increase [Ca2 +]i release and insulin secretion in islet beta-cells Chin Med Sci J 27 1 Mar 2012 18 23
27. K. Fujiwara, F. Maekawa, and T. Yada Oleic acid interacts with GPR40 to induce Ca2 + signaling in rat islet beta-cells: mediation by PLC and L-type Ca2 + channel and link to insulin release Am J Physiol Endocrinol Metab 289 4 Oct 2005 E670 E677
28. R. Fiume, G. Ramazzotti, I. Faenza, M. Piazzi, A. Bavelloni, and A.M. Billi et al. Nuclear PLCs affect insulin secretion by targeting PPARγ in pancreatic β cells FASEB J 26 1 2012 203 210
29. H.T. Wu, W. Chen, K.C. Cheng, P.M. Ku, C.H. Yeh, and J.T. Cheng Oleic acid activates peroxisome proliferator-activated receptor δ to compensate insulin resistance in steatotic cells J Nutr Biochem 23 10 Oct 2012 1264 1270
30. Q. Cheng, W. Dong, L. Qian, J. Wu, and Y. Peng Visfatin inhibits apoptosis of pancreatic β-cell line, MIN6, via the mitogen-activated protein kinase/phosphoinositide 3 -kinase pathway J Mol Endocrinol 47 1 Jul 4 2011 13 21