Glycosylation-related genes in NS0 cells are insensitive to moderately elevated ammonium concentrations

Journal of Biotechnology

Volumn 187, Issue , 2014, Pages 78-86

  Brodsky, Arthur Nathan ^a   Caldwell, Mary ^a   Bae, Sooneon ^a   Harcum, Sarah W ^a  

^a AMRL   (United States)

Author keywords

Biopharmaceuticals; CHO cells; DNA microarrays; Glycosylation; Mammalian cells

Indexed keywords

BIOASSAY; BIOCHIPS; CELL CULTURE; CELLS; ESTERIFICATION; GENE EXPRESSION; LAKES; POLYMERASE CHAIN REACTION; QUALITY CONTROL; RECOMBINANT PROTEINS;

AMMONIUM CONCENTRATIONS; BIOPHARMACEUTICALS; CHINESE HAMSTER OVARY CELLS; CHO CELL; DNA MICRO-ARRAY; MAMMALIAN CELLS; RECOMBINANT PROTEIN PRODUCTIONS; REVERSE TRANSCRIPTASES;

GLYCOSYLATION;

AMMONIA; BETA ACTIN; GLYCERALDEHYDE 3 PHOSPHATE DEHYDROGENASE; PROLINE; PROTEIN; SODIUM CHLORIDE; AMMONIUM DERIVATIVE; CULTURE MEDIUM; GLYCOSYLTRANSFERASE; NUCLEOTIDE; RNA DIRECTED DNA POLYMERASE;

ANIMAL CELL; ANIMAL CELL CULTURE; ARTICLE; BETA ACTIN GENE; BETA(1,4) GALACTOSYLTRANSFERASE GENE; CANCER CELL LINE; CELL STRESS; CHO CELL LINE; CONTROLLED STUDY; DNA MICROARRAY; GENE EXPRESSION; GENETIC ANALYSIS; GLYCERALDEHYDE 3 PHOSPHATE DEHYDROGENASE GENE; HOUSEKEEPING GENE; MOUSE; NONHUMAN; NS0 CELL LINE; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN GLYCOSYLATION; QUANTITATIVE ANALYSIS; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SOLUTE CARRIER FAMILY 35 GENE; ST3 BETA GALACTOSIDE ALPHA 2,3 SIALYLTRANSFERASE 3 GENE; ST3 BETA GALACTOSIDE ALPHA 2,3 SIALYLTRANSFERASE 4 GENE; ST3 BETA GALACTOSIDE ALPHA 2,3 SIALYLTRANSFERASE 6 GENE; ANIMAL; BIOREACTOR; CELL PROLIFERATION; CRICETULUS; CULTURE MEDIUM; DRUG EFFECTS; GENETICS; GLYCOSYLATION; HAMSTER; METABOLISM; TUMOR CELL LINE; ANIMAL MODEL;

AMMONIUM COMPOUNDS; ANIMALS; BIOREACTORS; CELL LINE, TUMOR; CELL PROLIFERATION; CHO CELLS; CRICETINAE; CRICETULUS; CULTURE MEDIA; GENE EXPRESSION; GLYCOSYLATION; GLYCOSYLTRANSFERASES; MICE; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS;

EID: 84906070955     PISSN: 01681656     EISSN: 18734863     Source Type: Journal    
DOI: 10.1016/j.jbiotec.2014.07.018     Document Type: Article

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