An investigation of intracellular glycosylation activities in CHO cells: Effects of nucleotide sugar precursor feeding

Biotechnology and Bioengineering

Volumn 107, Issue 2, 2010, Pages 321-336

  Wong, Niki S C ^a   Wati, Lydia ^a   Nissom, Peter M ^a   Feng, H T ^a   Lee, M M ^a   Yap, Miranda G S ^a,b  

^a AGENCY FOR SCIENCE   (Singapore)

^b NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

Author keywords

CHO cells; Gene expression; Glycosylation; Nucleotide sugars; Precursor feeding; Protein quality

Indexed keywords

CHO CELL; CYTIDINE; GLUCOSAMINES; GLYCOSYL TRANSFERASE; GLYCOSYLATION OF RECOMBINANT PROTEINS; N-GLYCOSYLATION; NUCLEOTIDE SUGAR; NUCLEOTIDE SUGARS; PRECURSOR FEEDING; PRODUCT QUALITY; PROTEIN QUALITY; RECOMBINANT HUMAN INTERFERON; SIALIC ACIDS; SIALYLATION; UNTREATED CONTROL; UP-REGULATION;

CAPILLARY ELECTROPHORESIS; CARBOXYLIC ACIDS; CELL CULTURE; ESTERIFICATION; FEEDING; GENE EXPRESSION; INTERFERONS; NUCLEOTIDES; SUBSTRATES; SUGAR (SUCROSE); CELLS; GLUCOSAMINE; RECOMBINANT PROTEINS; SUGARS;

GLYCOSYLATION;

CYTIDINE; GALACTOSE; GLUCOSAMINE; GLYCAN; HUMAN INTERFERON; RECOMBINANT GAMMA INTERFERON; SUGAR NUCLEOTIDE; URIDINE; RECOMBINANT PROTEIN; SIALIC ACID; SUGAR; GAMMA INTERFERON; GLYCOPROTEIN; HEXOSAMINE; N ACETYLMANNOSAMINE; N-ACETYLMANNOSAMINE; NUCLEOTIDE;

ANIMAL CELL; ARTICLE; B4GAL GENE; CAPILLARY ELECTROPHORESIS; CHO CELL; CONTROLLED STUDY; GENE; HUMAN; NONHUMAN; PRECURSOR; PROTEIN GLYCOSYLATION; RAT; SIALYLATION; ST3GAL GENE; UPREGULATION; CELL ACTIVITY; FEMALE; GLYCOSYLATION; ANIMAL; CARBOHYDRATE METABOLISM; CHEMISTRY; CRICETULUS; CULTURE MEDIUM; HAMSTER; METABOLISM;

LEPISOSTEIDAE;

ANIMALS; CARBOHYDRATE METABOLISM; CHO CELLS; CRICETINAE; CRICETULUS; CULTURE MEDIA; CYTIDINE; GALACTOSE; GLUCOSAMINE; GLYCOPROTEINS; GLYCOSYLATION; HEXOSAMINES; INTERFERON-GAMMA; NUCLEOTIDES; RECOMBINANT PROTEINS; URIDINE;

EID: 78149250500     PISSN: 00063592     EISSN: 10970290     Source Type: Journal    
DOI: 10.1002/bit.22812     Document Type: Article

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