Improvement of interferon-γ sialylation in Chinese hamster ovary cell culture by feeding of N-acetylmannosamine

Biotechnology and Bioengineering

Volumn 58, Issue 6, 1998, Pages 642-648

  Gu, Xuejun ^a   Wang, Daniel I C ^a  

^a MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

Author keywords

CHO cell culture; CMP sialic acid; Interferon ; N acetylmannosamine; Sialylation

Indexed keywords

AMINES; AMINO ACIDS; DRUG PRODUCTS; ENZYMES; INTERFERONS; PROTEINS; SUGARS;

AMINOSUGARS; GLYCOPROTEINS;

ANIMAL CELL CULTURE;

GAMMA INTERFERON; GLYCOPROTEIN; MANNOSAMINE;

ANIMAL CELL; ARTICLE; CELL GROWTH; CHINESE HAMSTER; ENZYME SUBSTRATE; NONHUMAN; OVARY CELL; PROTEIN PROTEIN INTERACTION; RECOMBINANT DNA TECHNOLOGY; SIALYLATION; STEM CELL;

ANIMALS; ASPARAGINE; CELL CULTURE TECHNIQUES; CELL DIVISION; CHO CELLS; CHROMATOGRAPHY, AFFINITY; CRICETINAE; CYTIDINE MONOPHOSPHATE N-ACETYLNEURAMINIC ACID; GLYCOSYLATION; HEXOSAMINES; HUMANS; INTERFERON TYPE II; INTERFERON-GAMMA, RECOMBINANT; RADIOISOTOPE DILUTION TECHNIQUE; RECOMBINANT FUSION PROTEINS; SIALIC ACIDS; TETRAHYDROFOLATE DEHYDROGENASE; TRANSFECTION; TRITIUM;

EID: 0032551285     PISSN: 00063592     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-0290(19980620)58:6<642::AID-BIT10>3.0.CO;2-9     Document Type: Article

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