메뉴 건너뛰기




Volumn 171, Issue 17, 2014, Pages 3988-4000

Immunosuppressive and anti-inflammatory properties of engineered nanomaterials

Author keywords

anti inflammatory properties; immune inhibition; immune system; immunosuppression; inflammation; nanoparticles

Indexed keywords

ANTIINFLAMMATORY AGENT; BETAMETHASONE SODIUM PHOSPHATE; BUTYRIC ACID; CELASTROL; CERIUM OXIDE; CHITOSAN; CORTICOSTEROID; CYCLOSPORIN; CYCLOSPORIN A; DENDRIMER; DEXAMETHASONE; DNA VACCINE; GLUCOSAMINE; IMMUNOSUPPRESSIVE AGENT; INDOMETACIN; LIPOSOME; MACROGOL; MAMMALIAN TARGET OF RAPAMYCIN INHIBITOR; METHOTREXATE; MYCOPHENOLIC ACID; NANOMATERIAL; NANOPARTICLE; NONSTEROID ANTIINFLAMMATORY AGENT; POLYGLACTIN; POLYLACTIC ACID; RAPAMYCIN; SMALL INTERFERING RNA; SOLID LIPID NANOPARTICLE; TACROLIMUS; UNINDEXED DRUG;

EID: 84906058627     PISSN: 00071188     EISSN: 14765381     Source Type: Journal    
DOI: 10.1111/bph.12722     Document Type: Review
Times cited : (88)

References (135)
  • 2
    • 59949091205 scopus 로고    scopus 로고
    • Diclofenac-loaded biopolymeric nanosuspensions for ophthalmic application
    • Agnihotri SM, Vavia PR, (2009). Diclofenac-loaded biopolymeric nanosuspensions for ophthalmic application. Nanomedicine 5: 90-95.
    • (2009) Nanomedicine , vol.5 , pp. 90-95
    • Agnihotri, S.M.1    Vavia, P.R.2
  • 6
    • 0030019226 scopus 로고    scopus 로고
    • Immunization with cholesterol-rich liposomes induces anti-cholesterol antibodies and reduces diet-induced hypercholesterolemia and plaque formation
    • Alving CR, Swartz GM Jr, Wassef NM, Ribas JL, Herderick EE, Virmani R, et-al. (1996). Immunization with cholesterol-rich liposomes induces anti-cholesterol antibodies and reduces diet-induced hypercholesterolemia and plaque formation. J Lab Clin Med 127: 40-49.
    • (1996) J Lab Clin Med , vol.127 , pp. 40-49
    • Alving, C.R.1    Swartz, Jr.G.M.2    Wassef, N.M.3    Ribas, J.L.4    Herderick, E.E.5    Virmani, R.6
  • 7
    • 77954671356 scopus 로고    scopus 로고
    • Liposomal encapsulation enhances and prolongs the anti-inflammatory effects of water-soluble dexamethasone phosphate in experimental adjuvant arthritis
    • Anderson R, Franch A, Castell M, Perez-Cano FJ, Bräuer R, Pohlers D, et-al. (2010). Liposomal encapsulation enhances and prolongs the anti-inflammatory effects of water-soluble dexamethasone phosphate in experimental adjuvant arthritis. Arthritis Res Ther 12: R147.
    • (2010) Arthritis Res Ther , vol.12
    • Anderson, R.1    Franch, A.2    Castell, M.3    Perez-Cano, F.J.4    Bräuer, R.5    Pohlers, D.6
  • 9
    • 77957844398 scopus 로고    scopus 로고
    • Polylactide-cyclosporin A nanoparticles for targeted immunosuppression
    • Azzi J, Tang L, Moore R, Tong R, El Haddad N, Akiyoshi T, et-al. (2010). Polylactide-cyclosporin A nanoparticles for targeted immunosuppression. FASEB J 24: 3927-3938.
    • (2010) FASEB J , vol.24 , pp. 3927-3938
    • Azzi, J.1    Tang, L.2    Moore, R.3    Tong, R.4    El Haddad, N.5    Akiyoshi, T.6
  • 10
    • 79959822366 scopus 로고    scopus 로고
    • Partially glycosylated dendrimers block MD-2 and prevent TLR4-MD-2-LPS complex mediated cytokine responses
    • Barata TS, Teo I, Brocchini S, Zloh M, Shaunak S, (2011). Partially glycosylated dendrimers block MD-2 and prevent TLR4-MD-2-LPS complex mediated cytokine responses. PLoS Comput Biol 7: e1002095.
    • (2011) PLoS Comput Biol , vol.7
    • Barata, T.S.1    Teo, I.2    Brocchini, S.3    Zloh, M.4    Shaunak, S.5
  • 11
    • 57749193735 scopus 로고    scopus 로고
    • Poly (lactide-co-glycolide)-polymethacrylate nanoparticles for intramuscular delivery of plasmid encoding interleukin-10 to prevent autoimmune diabetes in mice
    • Basarkar A, Singh J, (2009). Poly (lactide-co-glycolide)-polymethacrylate nanoparticles for intramuscular delivery of plasmid encoding interleukin-10 to prevent autoimmune diabetes in mice. Pharm Res 26: 72-81.
    • (2009) Pharm Res , vol.26 , pp. 72-81
    • Basarkar, A.1    Singh, J.2
  • 12
    • 0025267751 scopus 로고
    • Small colloidal gold conjugated to Fab fragments or to immunoglobulin G as high-resolution labels for electron microscopy: A technical overview
    • Baschong W, Wrigley NG, (1990). Small colloidal gold conjugated to Fab fragments or to immunoglobulin G as high-resolution labels for electron microscopy: a technical overview. J Electron Microsc Tech 14: 313-323.
    • (1990) J Electron Microsc Tech , vol.14 , pp. 313-323
    • Baschong, W.1    Wrigley, N.G.2
  • 14
    • 80455144192 scopus 로고    scopus 로고
    • Biomedical nanoparticles modulate specific CD4+ T cell stimulation by inhibition of antigen processing in dendritic cells
    • Blank F, Gerber P, Rothen-Rutishauser B, Sakulkhu U, Salaklang J, De Peyer K, et-al. (2011). Biomedical nanoparticles modulate specific CD4+ T cell stimulation by inhibition of antigen processing in dendritic cells. Nanotoxicology 5: 606-621.
    • (2011) Nanotoxicology , vol.5 , pp. 606-621
    • Blank, F.1    Gerber, P.2    Rothen-Rutishauser, B.3    Sakulkhu, U.4    Salaklang, J.5    De Peyer, K.6
  • 15
    • 84555197147 scopus 로고    scopus 로고
    • Interaction of nanoparticles with immunocompetent cells: Nanosafety considerations
    • Boraschi D, Costantino L, Italiani P, (2012). Interaction of nanoparticles with immunocompetent cells: nanosafety considerations. Nanomedicine (Lond) 7: 121-131.
    • (2012) Nanomedicine (Lond) , vol.7 , pp. 121-131
    • Boraschi, D.1    Costantino, L.2    Italiani, P.3
  • 16
    • 84868138089 scopus 로고    scopus 로고
    • Modulation of inflammatory signaling and cytokine release from microglia by celastrol incorporated into dendrimer nanocarriers
    • Boridy S, Soliman GM, Maysinger D, (2012). Modulation of inflammatory signaling and cytokine release from microglia by celastrol incorporated into dendrimer nanocarriers. Nanomedicine (Lond) 7: 1149-1165.
    • (2012) Nanomedicine (Lond) , vol.7 , pp. 1149-1165
    • Boridy, S.1    Soliman, G.M.2    Maysinger, D.3
  • 17
    • 0032855982 scopus 로고    scopus 로고
    • Tacrolimus whole blood concentrations correlate closely to side-effects in renal transplant recipients
    • Bottiger Y, Brattstrom C, Tyden G, Sawe J, Groth CG, (1999). Tacrolimus whole blood concentrations correlate closely to side-effects in renal transplant recipients. Br J Clin Pharmacol 48: 445-448.
    • (1999) Br J Clin Pharmacol , vol.48 , pp. 445-448
    • Bottiger, Y.1    Brattstrom, C.2    Tyden, G.3    Sawe, J.4    Groth, C.G.5
  • 18
    • 67649908422 scopus 로고    scopus 로고
    • Toxicity of antimony trioxide nanoparticles on human hematopoietic progenitor cells and comparison to cell lines
    • Bregoli L, Chiarini F, Gambarelli A, Sighinolfi G, Gatti AM, Santi P, et-al. (2009). Toxicity of antimony trioxide nanoparticles on human hematopoietic progenitor cells and comparison to cell lines. Toxicology 262: 121-129.
    • (2009) Toxicology , vol.262 , pp. 121-129
    • Bregoli, L.1    Chiarini, F.2    Gambarelli, A.3    Sighinolfi, G.4    Gatti, A.M.5    Santi, P.6
  • 20
    • 3342893024 scopus 로고    scopus 로고
    • Characterization of liposomal tacrolimus in lung surfactant-like phospholipids and evaluation of its immunosuppressive activity
    • Canadas O, Guerrero R, Garcia-Canero R, Orellana G, Menendez M, Casals C, (2004). Characterization of liposomal tacrolimus in lung surfactant-like phospholipids and evaluation of its immunosuppressive activity. Biochemistry 43: 9926-9938.
    • (2004) Biochemistry , vol.43 , pp. 9926-9938
    • Canadas, O.1    Guerrero, R.2    Garcia-Canero, R.3    Orellana, G.4    Menendez, M.5    Casals, C.6
  • 21
    • 26444523079 scopus 로고    scopus 로고
    • Characterization of indomethacin-loaded lipid nanoparticles by differential scanning calorimetry
    • Castelli F, Puglia C, Sarpietro MG, Rizza L, Bonina F, (2005). Characterization of indomethacin-loaded lipid nanoparticles by differential scanning calorimetry. Int J Pharm 304: 231-238.
    • (2005) Int J Pharm , vol.304 , pp. 231-238
    • Castelli, F.1    Puglia, C.2    Sarpietro, M.G.3    Rizza, L.4    Bonina, F.5
  • 22
    • 33750160205 scopus 로고    scopus 로고
    • The development of folate-PAMAM dendrimer conjugates for targeted delivery of anti-arthritic drugs and their pharmacokinetics and biodistribution in arthritic rats
    • Chandrasekar D, Sistla R, Ahmad FJ, Khar RK, Diwan PV, (2007). The development of folate-PAMAM dendrimer conjugates for targeted delivery of anti-arthritic drugs and their pharmacokinetics and biodistribution in arthritic rats. Biomaterials 28: 504-512.
    • (2007) Biomaterials , vol.28 , pp. 504-512
    • Chandrasekar, D.1    Sistla, R.2    Ahmad, F.J.3    Khar, R.K.4    Diwan, P.V.5
  • 23
    • 11944272030 scopus 로고    scopus 로고
    • Solubility enhancement of indomethacin with poly(amidoamine) dendrimers and targeting to inflammatory regions of arthritic rats
    • Chauhan AS, Jain NK, Diwan PV, Khopade AJ, (2004). Solubility enhancement of indomethacin with poly(amidoamine) dendrimers and targeting to inflammatory regions of arthritic rats. J Drug Target 12: 575-583.
    • (2004) J Drug Target , vol.12 , pp. 575-583
    • Chauhan, A.S.1    Jain, N.K.2    Diwan, P.V.3    Khopade, A.J.4
  • 24
    • 66149083636 scopus 로고    scopus 로고
    • Unexpected in vivo anti-inflammatory activity observed for simple, surface functionalized poly(amidoamine) dendrimers
    • Chauhan AS, Diwan PV, Jain NK, Tomalia DA, (2009). Unexpected in vivo anti-inflammatory activity observed for simple, surface functionalized poly(amidoamine) dendrimers. Biomacromolecules 10: 1195-1202.
    • (2009) Biomacromolecules , vol.10 , pp. 1195-1202
    • Chauhan, A.S.1    Diwan, P.V.2    Jain, N.K.3    Tomalia, D.A.4
  • 25
    • 84870337265 scopus 로고    scopus 로고
    • Rapamycin encapsulated in dual-responsive micelles for cancer therapy
    • Chen YC, Lo CL, Lin YF, Hsiue GH, (2013). Rapamycin encapsulated in dual-responsive micelles for cancer therapy. Biomaterials 34: 1115-1127.
    • (2013) Biomaterials , vol.34 , pp. 1115-1127
    • Chen, Y.C.1    Lo, C.L.2    Lin, Y.F.3    Hsiue, G.H.4
  • 26
    • 3042704505 scopus 로고    scopus 로고
    • Fullerene derivatives protect against oxidative stress in RAW 264.7 cells and ischemia-reperfused lungs
    • Chen YW, Hwang KC, Yen CC, Lai YL, (2004). Fullerene derivatives protect against oxidative stress in RAW 264.7 cells and ischemia-reperfused lungs. Am J Physiol Regul Integr Comp Physiol 287: R21-R26.
    • (2004) Am J Physiol Regul Integr Comp Physiol , vol.287
    • Chen, Y.W.1    Hwang, K.C.2    Yen, C.C.3    Lai, Y.L.4
  • 27
    • 33947499733 scopus 로고    scopus 로고
    • Transdermal delivery of nonsteroidal anti-inflammatory drugs mediated by polyamidoamine (PAMAM) dendrimers
    • Cheng Y, Man N, Xu T, Fu R, Wang X, Wen L, (2007). Transdermal delivery of nonsteroidal anti-inflammatory drugs mediated by polyamidoamine (PAMAM) dendrimers. J Pharm Sci 96: 595-602.
    • (2007) J Pharm Sci , vol.96 , pp. 595-602
    • Cheng, Y.1    Man, N.2    Xu, T.3    Fu, R.4    Wang, X.5    Wen, L.6
  • 28
    • 84900309395 scopus 로고    scopus 로고
    • Design and optimization of PLGA-based diclofenac loaded nanoparticles
    • Cooper DL, Harirforoosh S, (2014). Design and optimization of PLGA-based diclofenac loaded nanoparticles. PLoS ONE 9: e87326.
    • (2014) PLoS ONE , vol.9
    • Cooper, D.L.1    Harirforoosh, S.2
  • 29
    • 58949089131 scopus 로고    scopus 로고
    • Oral cyclosporine A - The current picture of its liposomal and other delivery systems
    • Czogalla A, (2009). Oral cyclosporine A-the current picture of its liposomal and other delivery systems. Cell Mol Biol Lett 14: 139-152.
    • (2009) Cell Mol Biol Lett , vol.14 , pp. 139-152
    • Czogalla, A.1
  • 31
    • 1842666678 scopus 로고    scopus 로고
    • Importance of immunotoxicity in safety assessment: A medical toxicologist's perspective
    • Descotes J, (2004). Importance of immunotoxicity in safety assessment: a medical toxicologist's perspective. Toxicol Lett 149: 103-108.
    • (2004) Toxicol Lett , vol.149 , pp. 103-108
    • Descotes, J.1
  • 32
    • 84865625466 scopus 로고    scopus 로고
    • Safety immunopharmacology: Evaluation of the adverse potential of pharmaceuticals on the immune system
    • Descotes J, (2012). Safety immunopharmacology: evaluation of the adverse potential of pharmaceuticals on the immune system. J Pharmacol Toxicol Methods 66: 79-83.
    • (2012) J Pharmacol Toxicol Methods , vol.66 , pp. 79-83
    • Descotes, J.1
  • 33
    • 33745611176 scopus 로고    scopus 로고
    • Cholesteryl butyrate solid lipid nanoparticles inhibit adhesion of human neutrophils to endothelial cells
    • Dianzani C, Cavalli R, Zara GP, Gallicchio M, Lombardi G, Gasco MR, et-al. (2006). Cholesteryl butyrate solid lipid nanoparticles inhibit adhesion of human neutrophils to endothelial cells. Br J Pharmacol 148: 648-656.
    • (2006) Br J Pharmacol , vol.148 , pp. 648-656
    • Dianzani, C.1    Cavalli, R.2    Zara, G.P.3    Gallicchio, M.4    Lombardi, G.5    Gasco, M.R.6
  • 34
    • 79953757604 scopus 로고    scopus 로고
    • Role of developmental immunotoxicity and immune dysfunction in chronic disease and cancer
    • Dietert RR, (2011). Role of developmental immunotoxicity and immune dysfunction in chronic disease and cancer. Reprod Toxicol 31: 319-326.
    • (2011) Reprod Toxicol , vol.31 , pp. 319-326
    • Dietert, R.R.1
  • 35
    • 23244457362 scopus 로고    scopus 로고
    • Inflammation and cancer: When NF-kappaB amalgamates the perilous partnership
    • Dobrovolskaia MA, Kozlov SV, (2005). Inflammation and cancer: when NF-kappaB amalgamates the perilous partnership. Curr Cancer Drug Targets 5: 325-344.
    • (2005) Curr Cancer Drug Targets , vol.5 , pp. 325-344
    • Dobrovolskaia, M.A.1    Kozlov, S.V.2
  • 36
    • 34547690726 scopus 로고    scopus 로고
    • Immunological properties of engineered nanomaterials
    • Dobrovolskaia MA, McNeil SE, (2007). Immunological properties of engineered nanomaterials. Nat Nanotechnol 2: 469-478.
    • (2007) Nat Nanotechnol , vol.2 , pp. 469-478
    • Dobrovolskaia, M.A.1    McNeil, S.E.2
  • 37
    • 51049108389 scopus 로고    scopus 로고
    • Preclinical studies to understand nanoparticle interaction with the immune system and its potential effects on nanoparticle biodistribution
    • Dobrovolskaia MA, Aggarwal P, Hall JB, McNeil SE, (2008). Preclinical studies to understand nanoparticle interaction with the immune system and its potential effects on nanoparticle biodistribution. Mol Pharm 5: 487-495.
    • (2008) Mol Pharm , vol.5 , pp. 487-495
    • Dobrovolskaia, M.A.1    Aggarwal, P.2    Hall, J.B.3    McNeil, S.E.4
  • 40
    • 0018885763 scopus 로고
    • Suspected anaphylactic reaction to Cremophor EL
    • Dye D, Watkins J, (1980). Suspected anaphylactic reaction to Cremophor EL. Br Med J 280: 1353.
    • (1980) Br Med J , vol.280 , pp. 1353
    • Dye, D.1    Watkins, J.2
  • 41
    • 84877267968 scopus 로고    scopus 로고
    • Cytokines as biomarkers of nanoparticle immunotoxicity
    • Elsabahy M, Wooley KL, (2013). Cytokines as biomarkers of nanoparticle immunotoxicity. Chem Soc Rev 42: 5552-5576.
    • (2013) Chem Soc Rev , vol.42 , pp. 5552-5576
    • Elsabahy, M.1    Wooley, K.L.2
  • 42
    • 0036067174 scopus 로고    scopus 로고
    • Liposomal tacrolimus lotion as a novel topical agent for treatment of immune-mediated skin disorders: Experimental studies in a murine model
    • Erdogan M, Wright JR Jr, McAlister VC, (2002). Liposomal tacrolimus lotion as a novel topical agent for treatment of immune-mediated skin disorders: experimental studies in a murine model. Br J Dermatol 146: 964-967.
    • (2002) Br J Dermatol , vol.146 , pp. 964-967
    • Erdogan, M.1    Wright, Jr.J.R.2    McAlister, V.C.3
  • 45
    • 84870953123 scopus 로고    scopus 로고
    • Microparticles bearing encephalitogenic peptides induce T-cell tolerance and ameliorate experimental autoimmune encephalomyelitis
    • Getts DR, Martin AJ, McCarthy DP, Terry RL, Hunter ZN, Yap WT, et-al. (2012). Microparticles bearing encephalitogenic peptides induce T-cell tolerance and ameliorate experimental autoimmune encephalomyelitis. Nat Biotechnol 30: 1217-1224.
    • (2012) Nat Biotechnol , vol.30 , pp. 1217-1224
    • Getts, D.R.1    Martin, A.J.2    McCarthy, D.P.3    Terry, R.L.4    Hunter, Z.N.5    Yap, W.T.6
  • 46
    • 84891691816 scopus 로고    scopus 로고
    • Improvement of the antiproliferative effect of rapamycin on tumor cell lines by poly (monomethylitaconate)-based pH-sensitive, plasma stable liposomes
    • Ghanbarzadeh S, Arami S, Pourmoazzen Z, Khorrami A, (2013). Improvement of the antiproliferative effect of rapamycin on tumor cell lines by poly (monomethylitaconate)-based pH-sensitive, plasma stable liposomes. Colloids Surf B Biointerfaces 115C: 323-330.
    • (2013) Colloids Surf B Biointerfaces , vol.115 C , pp. 323-330
    • Ghanbarzadeh, S.1    Arami, S.2    Pourmoazzen, Z.3    Khorrami, A.4
  • 48
    • 84868260201 scopus 로고    scopus 로고
    • Oral gene application using chitosan-DNA nanoparticles induces transferable tolerance
    • Goldmann K, Ensminger SM, Spriewald BM, (2012). Oral gene application using chitosan-DNA nanoparticles induces transferable tolerance. Clin Vaccine Immunol 19: 1758-1764.
    • (2012) Clin Vaccine Immunol , vol.19 , pp. 1758-1764
    • Goldmann, K.1    Ensminger, S.M.2    Spriewald, B.M.3
  • 49
    • 0035134749 scopus 로고    scopus 로고
    • Development and characterization of CyA-loaded poly(lactic acid)-poly(ethylene glycol)PEG micro- and nanoparticles. Comparison with conventional PLA particulate carriers
    • Gref R, Quellec P, Sanchez A, Calvo P, Dellacherie E, Alonso MJ, (2001). Development and characterization of CyA-loaded poly(lactic acid)-poly(ethylene glycol)PEG micro- and nanoparticles. Comparison with conventional PLA particulate carriers. Eur J Pharm Biopharm 51: 111-118.
    • (2001) Eur J Pharm Biopharm , vol.51 , pp. 111-118
    • Gref, R.1    Quellec, P.2    Sanchez, A.3    Calvo, P.4    Dellacherie, E.5    Alonso, M.J.6
  • 50
    • 84929993520 scopus 로고    scopus 로고
    • Toxicity screenings of nanomaterials: Challenges due to interference with assay processes and components of classic in vitro tests
    • doi: 10.3109/17435390.2013.829590.
    • Guadagnini R, Halamoda Kenzaoui B, Cartwright L, Pojana G, Magdolenova Z, Bilanicova D, et-al. (2013). Toxicity screenings of nanomaterials: challenges due to interference with assay processes and components of classic in vitro tests. Nanotoxicology. doi: 10.3109/17435390.2013.829590.
    • (2013) Nanotoxicology
    • Guadagnini, R.1    Halamoda Kenzaoui, B.2    Cartwright, L.3    Pojana, G.4    Magdolenova, Z.5    Bilanicova, D.6
  • 51
    • 74649084231 scopus 로고    scopus 로고
    • The Influences of cell type and ZnO nanoparticle size on immune cell cytotoxicity and cytokine induction
    • Hanley C, Thurber A, Hanna C, Punnoose A, Zhang J, Wingett DG, (2009). The Influences of cell type and ZnO nanoparticle size on immune cell cytotoxicity and cytokine induction. Nanoscale Res Lett 4: 1409-1420.
    • (2009) Nanoscale Res Lett , vol.4 , pp. 1409-1420
    • Hanley, C.1    Thurber, A.2    Hanna, C.3    Punnoose, A.4    Zhang, J.5    Wingett, D.G.6
  • 52
    • 42649132499 scopus 로고    scopus 로고
    • Protein nanoparticles as drug carriers in clinical medicine
    • Hawkins MJ, Soon-Shiong P, Desai N, (2008). Protein nanoparticles as drug carriers in clinical medicine. Adv Drug Deliv Rev 60: 876-885.
    • (2008) Adv Drug Deliv Rev , vol.60 , pp. 876-885
    • Hawkins, M.J.1    Soon-Shiong, P.2    Desai, N.3
  • 53
    • 79955703641 scopus 로고    scopus 로고
    • A phosphorus-based dendrimer targets inflammation and osteoclastogenesis in experimental arthritis
    • Hayder M, Poupot M, Baron M, Nigon D, Turrin CO, Caminade AM, et-al. (2011). A phosphorus-based dendrimer targets inflammation and osteoclastogenesis in experimental arthritis. Sci Transl Med 3: 81ra35.
    • (2011) Sci Transl Med , vol.3
    • Hayder, M.1    Poupot, M.2    Baron, M.3    Nigon, D.4    Turrin, C.O.5    Caminade, A.M.6
  • 55
    • 0036182057 scopus 로고    scopus 로고
    • Size-dependency of DL-lactide/glycolide copolymer particulates for intra-articular delivery system on phagocytosis in rat synovium
    • Horisawa E, Kubota K, Tuboi I, Sato K, Yamamoto H, Takeuchi H, et-al. (2002). Size-dependency of DL-lactide/glycolide copolymer particulates for intra-articular delivery system on phagocytosis in rat synovium. Pharm Res 19: 132-139.
    • (2002) Pharm Res , vol.19 , pp. 132-139
    • Horisawa, E.1    Kubota, K.2    Tuboi, I.3    Sato, K.4    Yamamoto, H.5    Takeuchi, H.6
  • 56
    • 58149215702 scopus 로고    scopus 로고
    • Chitosan/siRNA nanoparticle-mediated TNF-alpha knockdown in peritoneal macrophages for anti-inflammatory treatment in a murine arthritis model
    • Howard KA, Paludan SR, Behlke MA, Besenbacher F, Deleuran B, Kjems J, (2009). Chitosan/siRNA nanoparticle-mediated TNF-alpha knockdown in peritoneal macrophages for anti-inflammatory treatment in a murine arthritis model. Mol Ther 17: 162-168.
    • (2009) Mol Ther , vol.17 , pp. 162-168
    • Howard, K.A.1    Paludan, S.R.2    Behlke, M.A.3    Besenbacher, F.4    Deleuran, B.5    Kjems, J.6
  • 57
    • 61949341144 scopus 로고    scopus 로고
    • Host-guest chemistry and physicochemical properties of the dendrimer-mycophenolic acid complex
    • Hu J, Cheng Y, Ma Y, Wu Q, Xu T, (2009). Host-guest chemistry and physicochemical properties of the dendrimer-mycophenolic acid complex. J Phys Chem B 113: 64-74.
    • (2009) J Phys Chem B , vol.113 , pp. 64-74
    • Hu, J.1    Cheng, Y.2    Ma, Y.3    Wu, Q.4    Xu, T.5
  • 58
    • 84907028483 scopus 로고    scopus 로고
    • Inhibition of phosphoinositol 3 kinase contributes to nanoparticle-mediated exaggeration of endotoxin-induced leukocyte procoagulant activity
    • doi: 10.2217/NNM.13.137; [Epub ahead of print].
    • Ilinskaya AN, Man S, Patri AK, Clogston JD, Crist RM, Cachau RE, et-al. (2013). Inhibition of phosphoinositol 3 kinase contributes to nanoparticle-mediated exaggeration of endotoxin-induced leukocyte procoagulant activity. Nanomedicine (Lond). doi: 10.2217/NNM.13.137; [Epub ahead of print].
    • (2013) Nanomedicine (Lond)
    • Ilinskaya, A.N.1    Man, S.2    Patri, A.K.3    Clogston, J.D.4    Crist, R.M.5    Cachau, R.E.6
  • 59
    • 20444416369 scopus 로고    scopus 로고
    • Role of zinc in formulation of PLGA/PLA nanoparticles encapsulating betamethasone phosphate and its release profile
    • Ishihara T, Izumo N, Higaki M, Shimada E, Hagi T, Mine L, et-al. (2005). Role of zinc in formulation of PLGA/PLA nanoparticles encapsulating betamethasone phosphate and its release profile. J Control Release 105: 68-76.
    • (2005) J Control Release , vol.105 , pp. 68-76
    • Ishihara, T.1    Izumo, N.2    Higaki, M.3    Shimada, E.4    Hagi, T.5    Mine, L.6
  • 60
    • 65649115761 scopus 로고    scopus 로고
    • Treatment of experimental arthritis with stealth-type polymeric nanoparticles encapsulating betamethasone phosphate
    • Ishihara T, Kubota T, Choi T, Higaki M, (2009). Treatment of experimental arthritis with stealth-type polymeric nanoparticles encapsulating betamethasone phosphate. J Pharmacol Exp Ther 329: 412-417.
    • (2009) J Pharmacol Exp Ther , vol.329 , pp. 412-417
    • Ishihara, T.1    Kubota, T.2    Choi, T.3    Higaki, M.4
  • 61
    • 34249087392 scopus 로고    scopus 로고
    • PLGA nanoparticles for oral delivery of cyclosporine: Nephrotoxicity and pharmacokinetic studies in comparison to Sandimmune Neoral
    • Italia JL, Bhatt DK, Bhardwaj V, Tikoo K, Kumar MN, (2007). PLGA nanoparticles for oral delivery of cyclosporine: nephrotoxicity and pharmacokinetic studies in comparison to Sandimmune Neoral. J Control Release 119: 197-206.
    • (2007) J Control Release , vol.119 , pp. 197-206
    • Italia, J.L.1    Bhatt, D.K.2    Bhardwaj, V.3    Tikoo, K.4    Kumar, M.N.5
  • 62
    • 34250837518 scopus 로고    scopus 로고
    • A novel role for HMGB1 in TLR9-mediated inflammatory responses to CpG-DNA
    • Ivanov S, Dragoi AM, Wang X, Dallacosta C, Louten J, Musco G, et-al. (2007). A novel role for HMGB1 in TLR9-mediated inflammatory responses to CpG-DNA. Blood 110: 1970-1981.
    • (2007) Blood , vol.110 , pp. 1970-1981
    • Ivanov, S.1    Dragoi, A.M.2    Wang, X.3    Dallacosta, C.4    Louten, J.5    Musco, G.6
  • 64
    • 0642303108 scopus 로고    scopus 로고
    • Discovery of a potent nanoparticle P-selectin antagonist with anti-inflammatory effects in allergic airway disease
    • John AE, Lukacs NW, Berlin AA, Palecanda A, Bargatze RF, Stoolman LM, et-al. (2003). Discovery of a potent nanoparticle P-selectin antagonist with anti-inflammatory effects in allergic airway disease. FASEB J 17: 2296-2298.
    • (2003) FASEB J , vol.17 , pp. 2296-2298
    • John, A.E.1    Lukacs, N.W.2    Berlin, A.A.3    Palecanda, A.4    Bargatze, R.F.5    Stoolman, L.M.6
  • 65
    • 80051973171 scopus 로고    scopus 로고
    • Toxicity spectrum of inhibitors of mammalian target of rapamycin in organ transplantation: Etiology, pathogenesis and treatment
    • Kahan B, (2011). Toxicity spectrum of inhibitors of mammalian target of rapamycin in organ transplantation: etiology, pathogenesis and treatment. Expert Opin Drug Saf 10: 727-749.
    • (2011) Expert Opin Drug Saf , vol.10 , pp. 727-749
    • Kahan, B.1
  • 66
    • 84862925782 scopus 로고    scopus 로고
    • Zinc oxide nanoparticles interfere with zinc ion homeostasis to cause cytotoxicity
    • Kao YY, Chen YC, Cheng TJ, Chiung YM, Liu PS, (2012). Zinc oxide nanoparticles interfere with zinc ion homeostasis to cause cytotoxicity. Toxicol Sci 125: 462-472.
    • (2012) Toxicol Sci , vol.125 , pp. 462-472
    • Kao, Y.Y.1    Chen, Y.C.2    Cheng, T.J.3    Chiung, Y.M.4    Liu, P.S.5
  • 67
    • 15244339200 scopus 로고    scopus 로고
    • Synthesis, cellular transport, and activity of polyamidoamine dendrimer-methylprednisolone conjugates
    • Khandare J, Kolhe P, Pillai O, Kannan S, Lieh-Lai M, Kannan RM, (2005). Synthesis, cellular transport, and activity of polyamidoamine dendrimer-methylprednisolone conjugates. Bioconjug Chem 16: 330-337.
    • (2005) Bioconjug Chem , vol.16 , pp. 330-337
    • Khandare, J.1    Kolhe, P.2    Pillai, O.3    Kannan, S.4    Lieh-Lai, M.5    Kannan, R.M.6
  • 68
    • 33745014998 scopus 로고    scopus 로고
    • Efficient new cationic liposome formulation for systemic delivery of small interfering RNA silencing tumor necrosis factor alpha in experimental arthritis
    • Khoury M, Louis-Plence P, Escriou V, Noel D, Largeau C, Cantos C, et-al. (2006). Efficient new cationic liposome formulation for systemic delivery of small interfering RNA silencing tumor necrosis factor alpha in experimental arthritis. Arthritis Rheum 54: 1867-1877.
    • (2006) Arthritis Rheum , vol.54 , pp. 1867-1877
    • Khoury, M.1    Louis-Plence, P.2    Escriou, V.3    Noel, D.4    Largeau, C.5    Cantos, C.6
  • 69
    • 0035872889 scopus 로고    scopus 로고
    • Immunopathogenesis of delayed-type hypersensitivity
    • Kobayashi K, Kaneda K, Kasama T, (2001). Immunopathogenesis of delayed-type hypersensitivity. Microsc Res Tech 53: 241-245.
    • (2001) Microsc Res Tech , vol.53 , pp. 241-245
    • Kobayashi, K.1    Kaneda, K.2    Kasama, T.3
  • 70
    • 0038023185 scopus 로고    scopus 로고
    • Drug complexation, in vitro release and cellular entry of dendrimers and hyperbranched polymers
    • Kolhe P, Misra E, Kannan RM, Kannan S, Lieh-Lai M, (2003). Drug complexation, in vitro release and cellular entry of dendrimers and hyperbranched polymers. Int J Pharm 259: 143-160.
    • (2003) Int J Pharm , vol.259 , pp. 143-160
    • Kolhe, P.1    Misra, E.2    Kannan, R.M.3    Kannan, S.4    Lieh-Lai, M.5
  • 71
    • 84866019700 scopus 로고    scopus 로고
    • Interference of engineered nanoparticles with in vitro toxicity assays
    • Kroll A, Pillukat MH, Hahn D, Schnekenburger J, (2012). Interference of engineered nanoparticles with in vitro toxicity assays. Arch Toxicol 86: 1123-1136.
    • (2012) Arch Toxicol , vol.86 , pp. 1123-1136
    • Kroll, A.1    Pillukat, M.H.2    Hahn, D.3    Schnekenburger, J.4
  • 74
    • 43449095693 scopus 로고    scopus 로고
    • Liposomal glucocorticosteroids in treatment of chronic autoimmune demyelination: Long-term protective effects and enhanced efficacy of methylprednisolone formulations
    • Linker RA, Weller C, Luhder F, Mohr A, Schmidt J, Knauth M, et-al. (2008). Liposomal glucocorticosteroids in treatment of chronic autoimmune demyelination: long-term protective effects and enhanced efficacy of methylprednisolone formulations. Exp Neurol 211: 397-406.
    • (2008) Exp Neurol , vol.211 , pp. 397-406
    • Linker, R.A.1    Weller, C.2    Luhder, F.3    Mohr, A.4    Schmidt, J.5    Knauth, M.6
  • 75
    • 34547894266 scopus 로고    scopus 로고
    • Advanced delivery of ciclosporin A: Present state and perspective
    • Liu H, Wang Y, Li S, (2007). Advanced delivery of ciclosporin A: present state and perspective. Expert Opin Drug Deliv 4: 349-358.
    • (2007) Expert Opin Drug Deliv , vol.4 , pp. 349-358
    • Liu, H.1    Wang, Y.2    Li, S.3
  • 76
    • 84875822264 scopus 로고    scopus 로고
    • Nanogel-based delivery of mycophenolic acid ameliorates systemic lupus erythematosus in mice
    • Look M, Stern E, Wang QA, DiPlacido LD, Kashgarian M, Craft J, et-al. (2013). Nanogel-based delivery of mycophenolic acid ameliorates systemic lupus erythematosus in mice. J Clin Invest 123: 1741-1749.
    • (2013) J Clin Invest , vol.123 , pp. 1741-1749
    • Look, M.1    Stern, E.2    Wang, Q.A.3    Diplacido, L.D.4    Kashgarian, M.5    Craft, J.6
  • 77
    • 84887626813 scopus 로고    scopus 로고
    • The nanomaterial-dependent modulation of dendritic cells and its potential influence on therapeutic immunosuppression in lupus
    • Look M, Saltzman WM, Craft J, Fahmy TM, (2014). The nanomaterial- dependent modulation of dendritic cells and its potential influence on therapeutic immunosuppression in lupus. Biomaterials 35: 1089-1095.
    • (2014) Biomaterials , vol.35 , pp. 1089-1095
    • Look, M.1    Saltzman, W.M.2    Craft, J.3    Fahmy, T.M.4
  • 78
    • 12344281006 scopus 로고    scopus 로고
    • Innate defence functions of macrophages can be biased by nano-sized ceramic and metallic particles
    • Lucarelli M, Gatti AM, Savarino G, Quattroni P, Martinelli L, Monari E, et-al. (2004). Innate defence functions of macrophages can be biased by nano-sized ceramic and metallic particles. Eur Cytokine Netw 15: 339-346.
    • (2004) Eur Cytokine Netw , vol.15 , pp. 339-346
    • Lucarelli, M.1    Gatti, A.M.2    Savarino, G.3    Quattroni, P.4    Martinelli, L.5    Monari, E.6
  • 79
    • 77956010860 scopus 로고    scopus 로고
    • Gold nanoparticles attenuate LPS-induced NO production through the inhibition of NF-kappaB and IFN-beta/STAT1 pathways in RAW264.7 cells
    • Ma JS, Kim WJ, Kim JJ, Kim TJ, Ye SK, Song MD, et-al. (2010). Gold nanoparticles attenuate LPS-induced NO production through the inhibition of NF-kappaB and IFN-beta/STAT1 pathways in RAW264.7 cells. Nitric Oxide 23: 214-219.
    • (2010) Nitric Oxide , vol.23 , pp. 214-219
    • Ma, J.S.1    Kim, W.J.2    Kim, J.J.3    Kim, T.J.4    Ye, S.K.5    Song, M.D.6
  • 80
    • 70350393883 scopus 로고    scopus 로고
    • Effect of betamethasone phosphate loaded polymeric nanoparticles on a murine asthma model
    • Matsuo Y, Ishihara T, Ishizaki J, Miyamoto K, Higaki M, Yamashita N, (2009). Effect of betamethasone phosphate loaded polymeric nanoparticles on a murine asthma model. Cell Immunol 260: 33-38.
    • (2009) Cell Immunol , vol.260 , pp. 33-38
    • Matsuo, Y.1    Ishihara, T.2    Ishizaki, J.3    Miyamoto, K.4    Higaki, M.5    Yamashita, N.6
  • 81
    • 0035742029 scopus 로고    scopus 로고
    • The skin: Target organ in immunotoxicology of small-molecular-weight compounds
    • Merk HF, Sachs B, Baron J, (2001). The skin: target organ in immunotoxicology of small-molecular-weight compounds. Skin Pharmacol Appl Skin Physiol 14: 419-430.
    • (2001) Skin Pharmacol Appl Skin Physiol , vol.14 , pp. 419-430
    • Merk, H.F.1    Sachs, B.2    Baron, J.3
  • 82
    • 0038002438 scopus 로고    scopus 로고
    • Complete remission of experimental arthritis by joint targeting of glucocorticoids with long-circulating liposomes
    • Metselaar JM, Wauben MH, Wagenaar-Hilbers JP, Boerman OC, Storm G, (2003). Complete remission of experimental arthritis by joint targeting of glucocorticoids with long-circulating liposomes. Arthritis Rheum 48: 2059-2066.
    • (2003) Arthritis Rheum , vol.48 , pp. 2059-2066
    • Metselaar, J.M.1    Wauben, M.H.2    Wagenaar-Hilbers, J.P.3    Boerman, O.C.4    Storm, G.5
  • 83
    • 84876334686 scopus 로고    scopus 로고
    • Nanocolloids of indomethacin prepared using sonication and subsequent encapsulation with polysaccharide films
    • Milkova V, Kamburova K, Radeva T, (2013). Nanocolloids of indomethacin prepared using sonication and subsequent encapsulation with polysaccharide films. Colloids Surf B Biointerfaces 108: 279-284.
    • (2013) Colloids Surf B Biointerfaces , vol.108 , pp. 279-284
    • Milkova, V.1    Kamburova, K.2    Radeva, T.3
  • 84
    • 67651227154 scopus 로고    scopus 로고
    • Mechanisms for how inhaled multiwalled carbon nanotubes suppress systemic immune function in mice
    • Mitchell LA, Lauer FT, Burchiel SW, McDonald JD, (2009). Mechanisms for how inhaled multiwalled carbon nanotubes suppress systemic immune function in mice. Nat Nanotechnol 4: 451-456.
    • (2009) Nat Nanotechnol , vol.4 , pp. 451-456
    • Mitchell, L.A.1    Lauer, F.T.2    Burchiel, S.W.3    McDonald, J.D.4
  • 85
    • 83655211421 scopus 로고    scopus 로고
    • Designing micro- and nano-particles for treating rheumatoid arthritis
    • Mitragotri S, Yoo JW, (2011). Designing micro- and nano-particles for treating rheumatoid arthritis. Arch Pharm Res 34: 1887-1897.
    • (2011) Arch Pharm Res , vol.34 , pp. 1887-1897
    • Mitragotri, S.1    Yoo, J.W.2
  • 86
    • 79751516728 scopus 로고    scopus 로고
    • An increase in mouse tumor growth by an in vivo immunomodulating effect of titanium dioxide nanoparticles
    • Moon EY, Yi GH, Kang JS, Lim JS, Kim HM, Pyo S, (2011). An increase in mouse tumor growth by an in vivo immunomodulating effect of titanium dioxide nanoparticles. J Immunotoxicol 8: 56-67.
    • (2011) J Immunotoxicol , vol.8 , pp. 56-67
    • Moon, E.Y.1    Yi, G.H.2    Kang, J.S.3    Lim, J.S.4    Kim, H.M.5    Pyo, S.6
  • 87
    • 39849097998 scopus 로고    scopus 로고
    • Cyclosporine-loaded solid lipid nanoparticles (SLN): Drug-lipid physicochemical interactions and characterization of drug incorporation
    • Muller RH, Runge SA, Ravelli V, Thunemann AF, Mehnert W, Souto EB, (2008). Cyclosporine-loaded solid lipid nanoparticles (SLN): drug-lipid physicochemical interactions and characterization of drug incorporation. Eur J Pharm Biopharm 68: 535-544.
    • (2008) Eur J Pharm Biopharm , vol.68 , pp. 535-544
    • Muller, R.H.1    Runge, S.A.2    Ravelli, V.3    Thunemann, A.F.4    Mehnert, W.5    Souto, E.B.6
  • 88
    • 33646778115 scopus 로고    scopus 로고
    • Dendrimers as potential drug carriers. Part II. Prolonged delivery of ketoprofen by in vitro and in vivo studies
    • Na M, Yiyun C, Tongwen X, Yang D, Xiaomin W, Zhenwei L, et-al. (2006). Dendrimers as potential drug carriers. Part II. Prolonged delivery of ketoprofen by in vitro and in vivo studies. Eur J Med Chem 41: 670-674.
    • (2006) Eur J Med Chem , vol.41 , pp. 670-674
    • Na, M.1    Yiyun, C.2    Tongwen, X.3    Yang, D.4    Xiaomin, W.5    Zhenwei, L.6
  • 89
    • 31944451232 scopus 로고    scopus 로고
    • Toxic potential of materials at the nanolevel
    • Nel A, Xia T, Madler L, Li N, (2006). Toxic potential of materials at the nanolevel. Science 311: 622-627.
    • (2006) Science , vol.311 , pp. 622-627
    • Nel, A.1    Xia, T.2    Madler, L.3    Li, N.4
  • 90
    • 0343527232 scopus 로고    scopus 로고
    • Controlled release injectable liposomal gel of ibuprofen for epidural analgesia
    • Paavola A, Kilpelainen I, Yliruusi J, Rosenberg P, (2000). Controlled release injectable liposomal gel of ibuprofen for epidural analgesia. Int J Pharm 199: 85-93.
    • (2000) Int J Pharm , vol.199 , pp. 85-93
    • Paavola, A.1    Kilpelainen, I.2    Yliruusi, J.3    Rosenberg, P.4
  • 91
    • 79957984095 scopus 로고    scopus 로고
    • Nanoparticles and modulation of immune responses
    • (Pt 1).
    • Pantic I, (2011). Nanoparticles and modulation of immune responses. Sci Prog 94 (Pt 1): 97-107.
    • (2011) Sci Prog , vol.94 , pp. 97-107
    • Pantic, I.1
  • 92
    • 79952934026 scopus 로고    scopus 로고
    • Modulation of CD4+ T lymphocyte lineage outcomes with targeted, nanoparticle-mediated cytokine delivery
    • Park J, Gao W, Whiston R, Strom TB, Metcalfe S, Fahmy TM, (2011). Modulation of CD4+ T lymphocyte lineage outcomes with targeted, nanoparticle-mediated cytokine delivery. Mol Pharm 8: 143-152.
    • (2011) Mol Pharm , vol.8 , pp. 143-152
    • Park, J.1    Gao, W.2    Whiston, R.3    Strom, T.B.4    Metcalfe, S.5    Fahmy, T.M.6
  • 93
    • 84866151981 scopus 로고    scopus 로고
    • The use of anti-COX2 siRNA coated onto PLGA nanoparticles loading dexamethasone in the treatment of rheumatoid arthritis
    • Park JS, Yang HN, Jeon SY, Woo DG, Kim MS, Park KH, (2012). The use of anti-COX2 siRNA coated onto PLGA nanoparticles loading dexamethasone in the treatment of rheumatoid arthritis. Biomaterials 33: 8600-8612.
    • (2012) Biomaterials , vol.33 , pp. 8600-8612
    • Park, J.S.1    Yang, H.N.2    Jeon, S.Y.3    Woo, D.G.4    Kim, M.S.5    Park, K.H.6
  • 94
    • 0030840053 scopus 로고    scopus 로고
    • Streptokinase entrapment in interdigitation-fusion liposomes improves thrombolysis in an experimental rabbit model
    • Perkins WR, Vaughan DE, Plavin SR, Daley WL, Rauch J, Lee L, et-al. (1997). Streptokinase entrapment in interdigitation-fusion liposomes improves thrombolysis in an experimental rabbit model. Thromb Haemost 77: 1174-1178.
    • (1997) Thromb Haemost , vol.77 , pp. 1174-1178
    • Perkins, W.R.1    Vaughan, D.E.2    Plavin, S.R.3    Daley, W.L.4    Rauch, J.5    Lee, L.6
  • 95
    • 84864143124 scopus 로고    scopus 로고
    • Targeting tacrolimus to deeper layers of skin with improved safety for treatment of atopic dermatitis-Part II: In vivo assessment of dermatopharmacokinetics, biodistribution and efficacy
    • Pople PV, Singh KK, (2012). Targeting tacrolimus to deeper layers of skin with improved safety for treatment of atopic dermatitis-Part II: in vivo assessment of dermatopharmacokinetics, biodistribution and efficacy. Int J Pharm 434: 70-79.
    • (2012) Int J Pharm , vol.434 , pp. 70-79
    • Pople, P.V.1    Singh, K.K.2
  • 96
    • 84861842156 scopus 로고    scopus 로고
    • Quantum dots impair macrophagic morphology and the ability of phagocytosis by inhibiting the Rho-associated kinase signaling
    • Qu G, Zhang C, Yuan L, He J, Wang Z, Wang L, et-al. (2012). Quantum dots impair macrophagic morphology and the ability of phagocytosis by inhibiting the Rho-associated kinase signaling. Nanoscale 4: 2239-2244.
    • (2012) Nanoscale , vol.4 , pp. 2239-2244
    • Qu, G.1    Zhang, C.2    Yuan, L.3    He, J.4    Wang, Z.5    Wang, L.6
  • 97
    • 78650547540 scopus 로고    scopus 로고
    • An endogenous aryl hydrocarbon receptor ligand acts on dendritic cells and T cells to suppress experimental autoimmune encephalomyelitis
    • Quintana FJ, Murugaiyan G, Farez MF, Mitsdoerffer M, Tukpah AM, Burns EJ, et-al. (2010). An endogenous aryl hydrocarbon receptor ligand acts on dendritic cells and T cells to suppress experimental autoimmune encephalomyelitis. Proc Natl Acad Sci U S A 107: 20768-20773.
    • (2010) Proc Natl Acad Sci U S A , vol.107 , pp. 20768-20773
    • Quintana, F.J.1    Murugaiyan, G.2    Farez, M.F.3    Mitsdoerffer, M.4    Tukpah, A.M.5    Burns, E.J.6
  • 98
    • 22944488021 scopus 로고    scopus 로고
    • Dendrimer-like PEO glycopolymers exhibit anti-inflammatory properties
    • Rele SM, Cui W, Wang L, Hou S, Barr-Zarse G, Tatton D, et-al. (2005). Dendrimer-like PEO glycopolymers exhibit anti-inflammatory properties. J Am Chem Soc 127: 10132-10133.
    • (2005) J Am Chem Soc , vol.127 , pp. 10132-10133
    • Rele, S.M.1    Cui, W.2    Wang, L.3    Hou, S.4    Barr-Zarse, G.5    Tatton, D.6
  • 99
    • 70350767277 scopus 로고    scopus 로고
    • Development and characterization of liposomal formulations for rapamycin delivery and investigation of their antiproliferative effect on MCF7 cells
    • Rouf MA, Vural I, Renoir JM, Hincal AA, (2009). Development and characterization of liposomal formulations for rapamycin delivery and investigation of their antiproliferative effect on MCF7 cells. J Liposome Res 19: 322-331.
    • (2009) J Liposome Res , vol.19 , pp. 322-331
    • Rouf, M.A.1    Vural, I.2    Renoir, J.M.3    Hincal, A.A.4
  • 100
    • 79955932950 scopus 로고    scopus 로고
    • Therapeutic effect of stealth-type polymeric nanoparticles with encapsulated betamethasone phosphate on experimental autoimmune uveoretinitis
    • Sakai T, Ishihara T, Higaki M, Akiyama G, Tsuneoka H, (2011). Therapeutic effect of stealth-type polymeric nanoparticles with encapsulated betamethasone phosphate on experimental autoimmune uveoretinitis. Invest Ophthalmol Vis Sci 52: 1516-1521.
    • (2011) Invest Ophthalmol Vis Sci , vol.52 , pp. 1516-1521
    • Sakai, T.1    Ishihara, T.2    Higaki, M.3    Akiyama, G.4    Tsuneoka, H.5
  • 101
    • 82455217419 scopus 로고    scopus 로고
    • Functionalized STAT1 siRNA nanoparticles regress rheumatoid arthritis in a mouse model
    • Scheinman RI, Trivedi R, Vermillion S, Kompella UB, (2011). Functionalized STAT1 siRNA nanoparticles regress rheumatoid arthritis in a mouse model. Nanomedicine (Lond) 6: 1669-1682.
    • (2011) Nanomedicine (Lond) , vol.6 , pp. 1669-1682
    • Scheinman, R.I.1    Trivedi, R.2    Vermillion, S.3    Kompella, U.B.4
  • 102
    • 0043268760 scopus 로고    scopus 로고
    • Drug targeting by long-circulating liposomal glucocorticosteroids increases therapeutic efficacy in a model of multiple sclerosis
    • (Pt 8).
    • Schmidt J, Metselaar JM, Wauben MH, Toyka KV, Storm G, Gold R, (2003). Drug targeting by long-circulating liposomal glucocorticosteroids increases therapeutic efficacy in a model of multiple sclerosis. Brain 126 (Pt 8): 1895-1904.
    • (2003) Brain , vol.126 , pp. 1895-1904
    • Schmidt, J.1    Metselaar, J.M.2    Wauben, M.H.3    Toyka, K.V.4    Storm, G.5    Gold, R.6
  • 103
    • 80054764032 scopus 로고    scopus 로고
    • Liposomal encapsulation of glucocorticoids alters their mode of action in the treatment of experimental autoimmune encephalomyelitis
    • Schweingruber N, Haine A, Tiede K, Karabinskaya A, van den Brandt J, Wust S, et-al. (2011). Liposomal encapsulation of glucocorticoids alters their mode of action in the treatment of experimental autoimmune encephalomyelitis. J Immunol 187: 4310-4318.
    • (2011) J Immunol , vol.187 , pp. 4310-4318
    • Schweingruber, N.1    Haine, A.2    Tiede, K.3    Karabinskaya, A.4    Van Den Brandt, J.5    Wust, S.6
  • 104
    • 33646581965 scopus 로고    scopus 로고
    • Peripheral neuropathy induced by paclitaxel: Recent insights and future perspectives
    • Scripture CD, Figg WD, Sparreboom A, (2006). Peripheral neuropathy induced by paclitaxel: recent insights and future perspectives. Curr Neuropharmacol 4: 165-172.
    • (2006) Curr Neuropharmacol , vol.4 , pp. 165-172
    • Scripture, C.D.1    Figg, W.D.2    Sparreboom, A.3
  • 105
    • 84892918737 scopus 로고    scopus 로고
    • A rapamycin-binding protein polymer nanoparticle shows potent therapeutic activity in suppressing autoimmune dacryoadenitis in a mouse model of Sjogren's syndrome
    • Shah M, Edman MC, Janga SR, Shi P, Dhandhukia J, Liu S, et-al. (2013). A rapamycin-binding protein polymer nanoparticle shows potent therapeutic activity in suppressing autoimmune dacryoadenitis in a mouse model of Sjogren's syndrome. J Control Release 171: 269-279.
    • (2013) J Control Release , vol.171 , pp. 269-279
    • Shah, M.1    Edman, M.C.2    Janga, S.R.3    Shi, P.4    Dhandhukia, J.5    Liu, S.6
  • 106
    • 33750069158 scopus 로고    scopus 로고
    • Preparation, characterization and in vivo studies of proliposomes containing Cyclosporine A
    • Shah NM, Parikh J, Namdeo A, Subramanian N, Bhowmick S, (2006). Preparation, characterization and in vivo studies of proliposomes containing Cyclosporine A. J Nanosci Nanotechnol 6: 2967-2973.
    • (2006) J Nanosci Nanotechnol , vol.6 , pp. 2967-2973
    • Shah, N.M.1    Parikh, J.2    Namdeo, A.3    Subramanian, N.4    Bhowmick, S.5
  • 107
    • 3542993234 scopus 로고    scopus 로고
    • Polyvalent dendrimer glucosamine conjugates prevent scar tissue formation
    • Shaunak S, Thomas S, Gianasi E, Godwin A, Jones E, Teo I, et-al. (2004). Polyvalent dendrimer glucosamine conjugates prevent scar tissue formation. Nat Biotechnol 22: 977-984.
    • (2004) Nat Biotechnol , vol.22 , pp. 977-984
    • Shaunak, S.1    Thomas, S.2    Gianasi, E.3    Godwin, A.4    Jones, E.5    Teo, I.6
  • 108
    • 80155198296 scopus 로고    scopus 로고
    • A single exposure to iron oxide nanoparticles attenuates antigen-specific antibody production and T-cell reactivity in ovalbumin-sensitized BALB/c mice
    • Shen CC, Wang CC, Liao MH, Jan TR, (2011). A single exposure to iron oxide nanoparticles attenuates antigen-specific antibody production and T-cell reactivity in ovalbumin-sensitized BALB/c mice. Int J Nanomedicine 6: 1229-1235.
    • (2011) Int J Nanomedicine , vol.6 , pp. 1229-1235
    • Shen, C.C.1    Wang, C.C.2    Liao, M.H.3    Jan, T.R.4
  • 109
    • 84870330660 scopus 로고    scopus 로고
    • Iron oxide nanoparticles suppressed T helper 1 cell-mediated immunity in a murine model of delayed-type hypersensitivity
    • Shen CC, Liang HJ, Wang CC, Liao MH, Jan TR, (2012). Iron oxide nanoparticles suppressed T helper 1 cell-mediated immunity in a murine model of delayed-type hypersensitivity. Int J Nanomedicine 7: 2729-2737.
    • (2012) Int J Nanomedicine , vol.7 , pp. 2729-2737
    • Shen, C.C.1    Liang, H.J.2    Wang, C.C.3    Liao, M.H.4    Jan, T.R.5
  • 110
    • 75449119910 scopus 로고    scopus 로고
    • Preparation and evaluation of tacrolimus-loaded nanoparticles for lymphatic delivery
    • Shin SB, Cho HY, Kim DD, Choi HG, Lee YB, (2010). Preparation and evaluation of tacrolimus-loaded nanoparticles for lymphatic delivery. Eur J Pharm Biopharm 74: 164-171.
    • (2010) Eur J Pharm Biopharm , vol.74 , pp. 164-171
    • Shin, S.B.1    Cho, H.Y.2    Kim, D.D.3    Choi, H.G.4    Lee, Y.B.5
  • 111
    • 82455164104 scopus 로고    scopus 로고
    • Nanoparticle delivery of mycophenolic acid upregulates PD-L1 on dendritic cells to prolong murine allograft survival
    • Shirali AC, Look M, Du W, Kassis E, Stout-Delgado HW, Fahmy TM, et-al. (2011). Nanoparticle delivery of mycophenolic acid upregulates PD-L1 on dendritic cells to prolong murine allograft survival. Am J Transplant 11: 2582-2592.
    • (2011) Am J Transplant , vol.11 , pp. 2582-2592
    • Shirali, A.C.1    Look, M.2    Du, W.3    Kassis, E.4    Stout-Delgado, H.W.5    Fahmy, T.M.6
  • 112
    • 0034123971 scopus 로고    scopus 로고
    • Preparation and pharmacodynamic evaluation of liposomes of indomethacin
    • Srinath P, Vyas SP, Diwan PV, (2000). Preparation and pharmacodynamic evaluation of liposomes of indomethacin. Drug Dev Ind Pharm 26: 313-321.
    • (2000) Drug Dev Ind Pharm , vol.26 , pp. 313-321
    • Srinath, P.1    Vyas, S.P.2    Diwan, P.V.3
  • 113
    • 84873366290 scopus 로고    scopus 로고
    • Gold nanoparticles downregulate interleukin-1beta-induced pro-inflammatory responses
    • Sumbayev VV, Yasinska IM, Garcia CP, Gilliland D, Lall GS, Gibbs BF, et-al. (2012). Gold nanoparticles downregulate interleukin-1beta-induced pro-inflammatory responses. Small 9: 472-477.
    • (2012) Small , vol.9 , pp. 472-477
    • Sumbayev, V.V.1    Yasinska, I.M.2    Garcia, C.P.3    Gilliland, D.4    Lall, G.S.5    Gibbs, B.F.6
  • 114
    • 28244466864 scopus 로고    scopus 로고
    • Complement activation-related pseudoallergy: A new class of drug-induced acute immune toxicity
    • Szebeni J, (2005). Complement activation-related pseudoallergy: a new class of drug-induced acute immune toxicity. Toxicology 216: 106-121.
    • (2005) Toxicology , vol.216 , pp. 106-121
    • Szebeni, J.1
  • 115
    • 84862293445 scopus 로고    scopus 로고
    • Preparation and biopharmaceutical evaluation of tacrolimus loaded biodegradable nanoparticles for liver targeting
    • Tammam S, Mathur S, Afifi N, (2012). Preparation and biopharmaceutical evaluation of tacrolimus loaded biodegradable nanoparticles for liver targeting. J Biomed Nanotechnol 8: 439-449.
    • (2012) J Biomed Nanotechnol , vol.8 , pp. 439-449
    • Tammam, S.1    Mathur, S.2    Afifi, N.3
  • 116
    • 84874615718 scopus 로고    scopus 로고
    • Immunosuppressive activity of size-controlled PEG-PLGA nanoparticles containing encapsulated cyclosporine A
    • Tang L, Azzi J, Kwon M, Mounayar M, Tong R, Yin Q, et-al. (2012). Immunosuppressive activity of size-controlled PEG-PLGA nanoparticles containing encapsulated cyclosporine A. J Transplant 2012: 896141.
    • (2012) J Transplant , vol.2012 , pp. 896141
    • Tang, L.1    Azzi, J.2    Kwon, M.3    Mounayar, M.4    Tong, R.5    Yin, Q.6
  • 119
    • 84855394395 scopus 로고    scopus 로고
    • Size-dependent attenuation of TLR9 signaling by gold nanoparticles in macrophages
    • Tsai CY, Lu SL, Hu CW, Yeh CS, Lee GB, Lei HY, (2012). Size-dependent attenuation of TLR9 signaling by gold nanoparticles in macrophages. J Immunol 188: 68-76.
    • (2012) J Immunol , vol.188 , pp. 68-76
    • Tsai, C.Y.1    Lu, S.L.2    Hu, C.W.3    Yeh, C.S.4    Lee, G.B.5    Lei, H.Y.6
  • 121
    • 38049018037 scopus 로고    scopus 로고
    • Enhanced efficacy of diclofenac sodium-loaded lipogelosome formulation in intra-articular treatment of rheumatoid arthritis
    • Turker S, Erdogan S, Ozer YA, Bilgili H, Deveci S, (2008). Enhanced efficacy of diclofenac sodium-loaded lipogelosome formulation in intra-articular treatment of rheumatoid arthritis. J Drug Target 16: 51-57.
    • (2008) J Drug Target , vol.16 , pp. 51-57
    • Turker, S.1    Erdogan, S.2    Ozer, Y.A.3    Bilgili, H.4    Deveci, S.5
  • 122
    • 84861660607 scopus 로고    scopus 로고
    • Glucocorticoids in nano-liposomes administered intravenously and subcutaneously to adjuvant arthritis rats are superior to the free drugs in suppressing arthritis and inflammatory cytokines
    • Ulmansky R, Turjeman K, Baru M, Katzavian G, Harel M, Sigal A, et-al. (2012). Glucocorticoids in nano-liposomes administered intravenously and subcutaneously to adjuvant arthritis rats are superior to the free drugs in suppressing arthritis and inflammatory cytokines. J Control Release 160: 299-305.
    • (2012) J Control Release , vol.160 , pp. 299-305
    • Ulmansky, R.1    Turjeman, K.2    Baru, M.3    Katzavian, G.4    Harel, M.5    Sigal, A.6
  • 123
    • 82255175808 scopus 로고    scopus 로고
    • Immunogenicity of recombinant human interferon beta interacting with particles of glass, metal, and polystyrene
    • Van Beers MM, Gilli F, Schellekens H, Randolph TW, Jiskoot W, (2012). Immunogenicity of recombinant human interferon beta interacting with particles of glass, metal, and polystyrene. J Pharm Sci 101: 187-199.
    • (2012) J Pharm Sci , vol.101 , pp. 187-199
    • Van Beers, M.M.1    Gilli, F.2    Schellekens, H.3    Randolph, T.W.4    Jiskoot, W.5
  • 125
    • 58149096977 scopus 로고    scopus 로고
    • Human anti-gold antibodies: Biofunctionalization of gold nanoparticles and surfaces with anti-gold antibodies
    • Watanabe H, Nakanishi T, Umetsu M, Kumagai I, (2008). Human anti-gold antibodies: biofunctionalization of gold nanoparticles and surfaces with anti-gold antibodies. J Biol Chem 283: 36031-36038.
    • (2008) J Biol Chem , vol.283 , pp. 36031-36038
    • Watanabe, H.1    Nakanishi, T.2    Umetsu, M.3    Kumagai, I.4
  • 126
  • 127
    • 0028328762 scopus 로고
    • Potential neurotoxicity of the solvent vehicle for cyclosporine
    • Windebank AJ, Blexrud MD, de Groen PC, (1994). Potential neurotoxicity of the solvent vehicle for cyclosporine. J Pharmacol Exp Ther 268: 1051-1056.
    • (1994) J Pharmacol Exp Ther , vol.268 , pp. 1051-1056
    • Windebank, A.J.1    Blexrud, M.D.2    De Groen, P.C.3
  • 128
    • 84866756419 scopus 로고    scopus 로고
    • Preclinical evaluation of injectable sirolimus formulated with polymeric nanoparticle for cancer therapy
    • Woo HN, Chung HK, Ju EJ, Jung J, Kang HW, Lee SW, et-al. (2012). Preclinical evaluation of injectable sirolimus formulated with polymeric nanoparticle for cancer therapy. Int J Nanomedicine 7: 2197-2208.
    • (2012) Int J Nanomedicine , vol.7 , pp. 2197-2208
    • Woo, H.N.1    Chung, H.K.2    Ju, E.J.3    Jung, J.4    Kang, H.W.5    Lee, S.W.6
  • 130
    • 34848869675 scopus 로고    scopus 로고
    • Pharmacometrics and delivery of novel nanoformulated PEG-b-poly(epsilon- caprolactone) micelles of rapamycin
    • Yanez JA, Forrest ML, Ohgami Y, Kwon GS, Davies NM, (2008). Pharmacometrics and delivery of novel nanoformulated PEG-b-poly(epsilon- caprolactone) micelles of rapamycin. Cancer Chemother Pharmacol 61: 133-144.
    • (2008) Cancer Chemother Pharmacol , vol.61 , pp. 133-144
    • Yanez, J.A.1    Forrest, M.L.2    Ohgami, Y.3    Kwon, G.S.4    Davies, N.M.5
  • 131
    • 84863949288 scopus 로고    scopus 로고
    • Nanoparticle-mediated codelivery of myelin antigen and a tolerogenic small molecule suppresses experimental autoimmune encephalomyelitis
    • Yeste A, Nadeau M, Burns EJ, Weiner HL, Quintana FJ, (2012). Nanoparticle-mediated codelivery of myelin antigen and a tolerogenic small molecule suppresses experimental autoimmune encephalomyelitis. Proc Natl Acad Sci U S A 109: 11270-11275.
    • (2012) Proc Natl Acad Sci U S A , vol.109 , pp. 11270-11275
    • Yeste, A.1    Nadeau, M.2    Burns, E.J.3    Weiner, H.L.4    Quintana, F.J.5
  • 132
    • 37449030662 scopus 로고    scopus 로고
    • Preparation of rapamycin-loaded chitosan/PLA nanoparticles for immunosuppression in corneal transplantation
    • Yuan XB, Yuan YB, Jiang W, Liu J, Tian EJ, Shun HM, et-al. (2008). Preparation of rapamycin-loaded chitosan/PLA nanoparticles for immunosuppression in corneal transplantation. Int J Pharm 349: 241-248.
    • (2008) Int J Pharm , vol.349 , pp. 241-248
    • Yuan, X.B.1    Yuan, Y.B.2    Jiang, W.3    Liu, J.4    Tian, E.J.5    Shun, H.M.6
  • 133
    • 79251551386 scopus 로고    scopus 로고
    • Percutaneous permeation of betamethasone 17-valerate incorporated in lipid nanoparticles
    • Zhang J, Smith E, (2011). Percutaneous permeation of betamethasone 17-valerate incorporated in lipid nanoparticles. J Pharm Sci 100: 896-903.
    • (2011) J Pharm Sci , vol.100 , pp. 896-903
    • Zhang, J.1    Smith, E.2
  • 134
    • 77955537470 scopus 로고    scopus 로고
    • Treatment of experimental autoimmune uveoretinitis with intravitreal injection of tacrolimus (FK506) encapsulated in liposomes
    • Zhang R, He R, Qian J, Guo J, Xue K, Yuan YF, (2010). Treatment of experimental autoimmune uveoretinitis with intravitreal injection of tacrolimus (FK506) encapsulated in liposomes. Invest Ophthalmol Vis Sci 51: 3575-3582.
    • (2010) Invest Ophthalmol Vis Sci , vol.51 , pp. 3575-3582
    • Zhang, R.1    He, R.2    Qian, J.3    Guo, J.4    Xue, K.5    Yuan, Y.F.6
  • 135
    • 0035003021 scopus 로고    scopus 로고
    • Role of formulation vehicles in taxane pharmacology
    • van Zuylen L, Verweij J, Sparreboom A, (2001). Role of formulation vehicles in taxane pharmacology. Invest New Drugs 19: 125-141.
    • (2001) Invest New Drugs , vol.19 , pp. 125-141
    • Van Zuylen, L.1    Verweij, J.2    Sparreboom, A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.