-
1
-
-
85010187334
-
-
O'Neal, M.J., Heckelman, P.E., Koch, C.B., Roman, K.J., Kenny, C.M. and D'Arecca, M.R. (Eds) Merck & Co., Inc., Whitehouse Station, NJ, USA
-
th edition, Merck & Co., Inc., Whitehouse Station, NJ, USA, 2006, 2753.
-
(2006)
th Edition
, pp. 2753
-
-
-
2
-
-
0029688322
-
Biosynthesis and mechanism of action of cyclosporins
-
Laven, A. Biosynthesis and mechanism of action of cyclosporins. Prog. Med. Chem. 33 (1996) 53-97.
-
(1996)
Prog. Med. Chem.
, vol.33
, pp. 53-97
-
-
Laven, A.1
-
3
-
-
0021341035
-
Total synthesis of "cyclosporin A" and "cyclosporin H", two fungal metabolites isolated from species Tolypocladium inflatum Gams
-
Wenger, R.M. Total synthesis of "cyclosporin A" and "cyclosporin H", two fungal metabolites isolated from species Tolypocladium inflatum Gams. Helv. Chim. Acta 67 (1984) 503-515.
-
(1984)
Helv. Chim. Acta
, vol.67
, pp. 503-515
-
-
Wenger, R.M.1
-
4
-
-
33747795904
-
Disease, destination, dose and delivery aspects of ciclosporin: The state of the art
-
DOI 10.1016/j.drudis.2006.07.015, PII S1359644606002911
-
Italia, J.L., Bhardwaj, V. and Kumar, M.N.V.R. Disease, destination, dose and delivery aspects of ciclosporin: the state of the art. Drug Discov. Today 11 (2006) 846-854. (Pubitemid 44280030)
-
(2006)
Drug Discovery Today
, vol.11
, Issue.17-18
, pp. 846-854
-
-
Italia, J.L.1
Bhardwaj, V.2
Ravi Kumar, M.N.V.3
-
5
-
-
84978736577
-
Cyclosporins: Recent developments in biosynthesis, pharmacology and biology, and clinical applications
-
Rehm, H.J., Reed, G., Puhler, A. and vonDohren, H., Eds, VCH Verlagsgesellschaft, Weinheim
-
Kallen, J., Mikol, V., Quesniaux, V.F.J., Walkinshaw, M.D., Schneider- Scherzer, E.S., Schorgendorfer, K., Weber, G. and Fliri, H.G. Cyclosporins: recent developments in biosynthesis, pharmacology and biology, and clinical applications. in: Biotechnology, a Multivolume Comprehensive Treatise (Rehm, H.J., Reed, G., Puhler, A. and vonDohren, H., Eds), Vol.7, VCH Verlagsgesellschaft, Weinheim, 1997, 535-591.
-
(1997)
Biotechnology, a Multivolume Comprehensive Treatise
, vol.7
, pp. 535-591
-
-
Kallen, J.1
Mikol, V.2
Quesniaux, V.F.J.3
Walkinshaw, M.D.4
Schneider-Scherzer, E.S.5
Schorgendorfer, K.6
Weber, G.7
Fliri, H.G.8
-
6
-
-
68949141134
-
Pharmacology and Pharmacokinetics of cyclosporin a
-
Borel, J.F. Pharmacology and Pharmacokinetics of cyclosporin A. Transpl. Clin. Immunol. 13 (1981) 3-6.
-
(1981)
Transpl. Clin. Immunol.
, vol.13
, pp. 3-6
-
-
Borel, J.F.1
-
7
-
-
0026644021
-
Progress towards a molecular understanding of cyclosporine A-mediated immunosupression
-
Schumacher, A. and Nordheim, A. Progress towards a molecular understanding of cyclosporine A-mediated immunosupression. Clin. Investig. 70 (1992) 773-779.
-
(1992)
Clin. Investig.
, vol.70
, pp. 773-779
-
-
Schumacher, A.1
Nordheim, A.2
-
8
-
-
1642312100
-
Experience with cyclosporine
-
Ready, A. Experience with cyclosporine. Transplant. Proc. 36 (2004) 135S-138S.
-
(2004)
Transplant. Proc.
, vol.36
-
-
Ready, A.1
-
9
-
-
1642378810
-
Cyclosporine nephrotoxicity
-
Busauschina, A. Cyclosporine nephrotoxicity. Transplant. Proc. 36 (2004) 2295-2335.
-
(2004)
Transplant. Proc.
, vol.36
, pp. 2295-2335
-
-
Busauschina, A.1
-
10
-
-
0031983495
-
Impaired antioxidant defense system in the kidney tissues from rabbits treated with cyclosporine. Protective effects of vitamins e and C
-
Durak, I., Karabacak, H.I., Buyukkocak, S., Cimen, M.Y., Kacmaz, M., Omeroglu, E. and Ozturk, H.S. Impaired antioxidant defense system in the kidney tissues from rabbits treated with cyclosporine. Protective effects of vitamins E and C. Nephron 78 (1998) 207-211.
-
(1998)
Nephron
, vol.78
, pp. 207-211
-
-
Durak, I.1
Karabacak, H.I.2
Buyukkocak, S.3
Cimen, M.Y.4
Kacmaz, M.5
Omeroglu, E.6
Ozturk, H.S.7
-
11
-
-
20444488772
-
Protective role of melatonin in cyclosporine A-induced oxidative stress in rat liver
-
DOI 10.1016/j.intimp.2005.03.021, PII S1567576905000780
-
Rezzani, R., Buffoli, B., Rodella, L., Stacchioti, A. and Bianchi, R. Protective role of melatonin in cyclosporine A-induced oxidative stress in rat liver. Int. Immunopharmacol. 5 (2005) 1397-1405. (Pubitemid 40813296)
-
(2005)
International Immunopharmacology
, vol.5
, Issue.9
, pp. 1397-1405
-
-
Rezzani, R.1
Buffoli, B.2
Rodella, L.3
Stacchiotti, A.4
Bianchi, R.5
-
12
-
-
1642352670
-
Therapeutic drug monitoring of cyclosporine: 20 years of progress
-
Kahan, B.D. Therapeutic drug monitoring of cyclosporine: 20 years of progress. Transplant. Proc. 36 (2004) 378s-391s.
-
(2004)
Transplant. Proc.
, vol.36
-
-
Kahan, B.D.1
-
13
-
-
0017116274
-
Crystal and molecular structure of an iodo-derivative of the cyclic undecapeptide cyclosporin a
-
Petcher, T.J., Weber, H. and Ruegger, A. Crystal and molecular structure of an iodo-derivative of the cyclic undecapeptide cyclosporin A. Helv. Chim. Acta 59 (1976) 1480-1489.
-
(1976)
Helv. Chim. Acta
, vol.59
, pp. 1480-1489
-
-
Petcher, T.J.1
Weber, H.2
Ruegger, A.3
-
14
-
-
0027141121
-
Solvent-dependent conformation and hydrogen-bonding capacity of cyclosporin A: Evidence from partition coefficients and molecular dynamics simulations
-
DOI 10.1021/jm00076a002
-
El Tayar, N., Mark, A.E., Vallat, P., Brunne, R.M., Testa, B. and van Gunsteren, W.F. Solvent-dependent conformation and hydrogen-bonding capacity of cyclosporin A: evidence from partition coefficients and molecular dynamics simulations. J. Med. Chem. 36 (1993) 3757-3764. (Pubitemid 24006703)
-
(1993)
Journal of Medicinal Chemistry
, vol.36
, Issue.24
, pp. 3757-3764
-
-
El Tayar, N.1
Mark, A.E.2
Vallat, P.3
Brunne, R.M.4
Testa, B.5
Van Gunsteren, W.F.6
-
15
-
-
70350058219
-
-
Sigma. Cyclosporin A. 1996 Sigma Chemical Co.
-
Sigma. Product Information. Cyclosporin A. 1996 Sigma Chemical Co.
-
Product Information.
-
-
-
16
-
-
0041837235
-
Properties and stability of a liquid crystal form of cyclosporine - The first reported naturally occurring peptide that exists as a thermotropic liquid crystal
-
DOI 10.1002/jps.10444
-
Lechuga-Ballesteros, D., Abdul-Fattach, A., Stevenson, C.L. and Bennett, D.B. Properties and stability of a liquid crystal form of cyclosporine - the first reported naturally occurring peptide that exists as a thermotropic liquid crystal. J. Pharm. Sci. 92 (2003) 1821-1831. (Pubitemid 37071815)
-
(2003)
Journal of Pharmaceutical Sciences
, vol.92
, Issue.9
, pp. 1821-1831
-
-
Lechuga-Ballesteros, D.1
Abdul-Fattah, A.2
Stevenson, C.L.3
Bennett, D.B.4
-
17
-
-
0025752973
-
Unusual solubility behavior of cyclosporin a in aqueous media
-
Ismailos, G., Peppas, C., Dressman, J. and Macheras, P. Unusual solubility behavior of cyclosporin A in aqueous media. J. Pharm. Pharmacol. 43 (1991) 287-289.
-
(1991)
J. Pharm. Pharmacol.
, vol.43
, pp. 287-289
-
-
Ismailos, G.1
Peppas, C.2
Dressman, J.3
Macheras, P.4
-
18
-
-
0036278468
-
Interactions of cyclosporines with lipid membranes as studied by solid-state nuclear magnetic resonance spectroscopy and high-sensitivity titration calorimetry
-
DOI 10.1002/jps.10071
-
Schote, U., Ganz, P., Fahr, A. and Seelig, J. Interactions of cyclosporines with lipid membranes as studied by solid-state nuclear magnetic resonance spectroscopy and high-sensitivity titration calorimetry. J. Pharm. Sci. 91 (2002) 856-867. (Pubitemid 34639648)
-
(2002)
Journal of Pharmaceutical Sciences
, vol.91
, Issue.3
, pp. 856-867
-
-
Schote, U.1
Ganz, P.2
Fahr, A.3
Seelig, J.4
-
19
-
-
0028077907
-
Effect of temperature on molecular structure of cyclosporin a
-
Hasumi, H., Nishikawa, T. and Ohtani, H. Effect of temperature on molecular structure of cyclosporin A. Biochem. Mol. Biol. Int. 34 (1994) 505-511. (Pubitemid 24325414)
-
(1994)
Biochemistry and Molecular Biology International
, vol.34
, Issue.3
, pp. 505-511
-
-
Hasumi, H.1
Nishikawa, T.2
Ohtani, H.3
-
20
-
-
33744973517
-
®) versus drug nanocrystals
-
DOI 10.1016/j.ijpharm.2006.02.045, PII S037851730600192X
-
Mueller, R.H., Runge, S., Ravelli, V., Mehnert, W., Thunemann, A.F. and Souto, E.B. Oral bioavailability of cyclosporine: solid lipid nanoparticles (SLN® ) versus drug nanocrystals. Int. J. Pharm. 317 (2006) 82-89. (Pubitemid 43866342)
-
(2006)
International Journal of Pharmaceutics
, vol.317
, Issue.1
, pp. 82-89
-
-
Muller, R.H.1
Runge, S.2
Ravelli, V.3
Mehnert, W.4
Thunemann, A.F.5
Souto, E.B.6
-
21
-
-
1542511351
-
Cyclosporin a prodrugs: Design, synthesis and biophysical properties
-
DOI 10.1111/j.1399-3011.2003.00111.x
-
Hamel, A.R., Hubler, F., Carrupt, A., Wenger, R.M. and Mutter, M. Cyclosporin A prodrugs: design, synthesis and biophysical properties. J. Peptide Res. 63 (2004) 147-154. (Pubitemid 38333843)
-
(2004)
Journal of Peptide Research
, vol.63
, Issue.2
, pp. 147-154
-
-
Hamel, A.R.1
Hubler, F.2
Carrupt, A.3
Wenger, R.M.4
Mutter, M.5
-
22
-
-
23244446159
-
A water-soluble prodrug of cyclosporine a for ocular application: A stability study
-
DOI 10.1016/j.ejps.2005.05.003, PII S0928098705001697
-
Lallemand, F., Perottet, P., Felt-Baeyens, O., Kloeti, W., Philippoz, F., Marfurt, J., Besseghir, K. and Gurny, R. A water-soluble prodrug of cyclosporine A for ocular application: a stability study. Eur. J. Pharm. Sci. 26 (2005) 124-129. (Pubitemid 41097269)
-
(2005)
European Journal of Pharmaceutical Sciences
, vol.26
, Issue.1
, pp. 124-129
-
-
Lallemand, F.1
Perottet, P.2
Felt-Baeyens, O.3
Kloeti, W.4
Philippoz, F.5
Marfurt, J.6
Besseghir, K.7
Gurny, R.8
-
23
-
-
23144445682
-
Solubilization of Cyclosporin a
-
Ran, Y., Zhao, L., Xu, Q. and Yalkowsky, S.H. Solubilization of Cyclosporin A. AAPS Pharm. Sci. Tech. 2 (2001) 2.
-
(2001)
AAPS Pharm. Sci. Tech.
, vol.2
, pp. 2
-
-
Ran, Y.1
Zhao, L.2
Xu, Q.3
Yalkowsky, S.H.4
-
24
-
-
0025835156
-
The NMR structure of cyclosporin a bound to cyclophilin in aqueous solution
-
Weber, C., Wider, G., von Freyberg, B., Traber, R., Braun, W., Widmer, H. and Wuthrich, K. The NMR structure of cyclosporin A bound to cyclophilin in aqueous solution. Biochemistry 30 (1991) 6563-6574.
-
(1991)
Biochemistry
, vol.30
, pp. 6563-6574
-
-
Weber, C.1
Wider, G.2
Von Freyberg, B.3
Traber, R.4
Braun, W.5
Widmer, H.6
Wuthrich, K.7
-
25
-
-
0026532051
-
A conformation of cyclosporin a in aqueous environment revealed by the X-ray structure of a cyclosporin-Fab complex
-
Altschuh, D., Vix, O., Rees, B. and Thierry, J.C. A conformation of cyclosporin A in aqueous environment revealed by the X-ray structure of a cyclosporin-Fab complex. Science 256 (1992) 92-94.
-
(1992)
Science
, vol.256
, pp. 92-94
-
-
Altschuh, D.1
Vix, O.2
Rees, B.3
Thierry, J.C.4
-
26
-
-
24744450020
-
Structure refinement of cyclosporin a in chloroform by using RDCs measured in a stretched PDMS-gel
-
DOI 10.1002/cbic.200500146
-
Klages, J., Neubauer, C., Coles, M., Kessler, H. and Luy, B. Structure refinement of cyclosporin A in chloroform by using RDCs measured in a stretched PDMS-gel. Chembiochem 6 (2005) 1672-1678. (Pubitemid 41296975)
-
(2005)
ChemBioChem
, vol.6
, Issue.9
, pp. 1672-1678
-
-
Klages, J.1
Neubauer, C.2
Coles, M.3
Kessler, H.4
Luy, B.5
-
27
-
-
39749107259
-
Crystal structure of human cyclophilin D in complex with its inhibitor, cyclosporin a at 0.96-Å resolution
-
DOI 10.1002/prot.21855
-
Kajitani, K., Fujihashi, M., Kobayashi, Y., Shimizu, S., Tsujimoto, Y. and Miki, K. Crystal structure of human cyclophilin D in complex with its inhibitor, cyclosporine A at 0.96-Å resolution. Proteins 70 (2008) 1635-1639. (Pubitemid 351304121)
-
(2008)
Proteins: Structure, Function and Genetics
, vol.70
, Issue.4
, pp. 1635-1639
-
-
Kajitani, K.1
Fujihashi, M.2
Kobayashi, Y.3
Shimizu, S.4
Tsujimoto, Y.5
Miki, K.6
-
28
-
-
0028807559
-
Liposomal cyclosporine. Characterization of drug incorporation and interbilayer exchange
-
Ouyang, C., Choice, E., Holland, J., Meloche, M. and Madden, T.D. Liposomal cyclosporine. Characterization of drug incorporation and interbilayer exchange. Transplantation 60 (1995) 999-1006.
-
(1995)
Transplantation
, vol.60
, pp. 999-1006
-
-
Ouyang, C.1
Choice, E.2
Holland, J.3
Meloche, M.4
Madden, T.D.5
-
29
-
-
0033390633
-
Biophysical characterisation of liposomal delivery systems for lipophilic drugs: Cyclosporin a as an example
-
Fahr, A. and Reiter, G. Biophysical characterisation of liposomal delivery systems for lipophilic drugs: Cyclosporin A as an example. Cell. Mol. Biol. Lett. 4 (1999) 611-623. (Pubitemid 30016986)
-
(1999)
Cellular and Molecular Biology Letters
, vol.4
, Issue.4
, pp. 611-623
-
-
Fahr, A.1
Reiter, G.2
-
30
-
-
0029082257
-
Liposomal formulations of Cyclosporin A: Influence of lipid type and dose on pharmacokinetics
-
Fahr, A., Holz, M. and Fricker, G. Liposomal formulations of Cyclosporin A: influence of lipid type and dose on pharmacokinetics. Pharm. Res. 12 (1995) 1189-1197.
-
(1995)
Pharm. Res.
, vol.12
, pp. 1189-1197
-
-
Fahr, A.1
Holz, M.2
Fricker, G.3
-
31
-
-
0027943319
-
Interactions of cyclosporine and some derivatives with model membranes: Binding and ion permeability changes
-
Fahr, A., Nimmerfall, F. and Wenger, R. Interactions of Cyclosporin A and some derivatives with model membranes: Binding and ion permeability changes. Transplant. Proc. 26 (1994) 2837-2841. (Pubitemid 24329335)
-
(1994)
Transplantation Proceedings
, vol.26
, Issue.5
, pp. 2837-2841
-
-
Fahr, A.1
Nimmerfall, F.2
Wenger, R.3
-
32
-
-
24644453083
-
Transfer of lipophilic drugs between liposomal membranes and biological interfaces: Consequences for drug delivery
-
DOI 10.1016/j.ejps.2005.05.012, PII S0928098705001922
-
Fahr, A., van Hoogevest, P., May, S., Bergstrand, N. and Leigh, M.L.S. Transfer of lipophilic drugs between liposomal membranes and biological interfaces: consequences for drug delivery. Eur. J. Pharm. Sci. 26 (2005) 251-265. (Pubitemid 41278632)
-
(2005)
European Journal of Pharmaceutical Sciences
, vol.26
, Issue.3-4
, pp. 251-265
-
-
Fahr, A.1
Hoogevest, P.V.2
May, S.3
Bergstrand, N.4
Leigh, M.L.S.5
-
33
-
-
3042691771
-
Effects of cyclosporin a on model lipid membranes
-
DOI 10.1016/j.chemphyslip.2004.04.002, PII S0009308404000490
-
Lambros, M.P. and Rahman, Y.E. Effects of cyclosporin A on model lipid membranes. Chem. Phys. Lipids 131 (2004) 63-69. (Pubitemid 38802862)
-
(2004)
Chemistry and Physics of Lipids
, vol.131
, Issue.1
, pp. 63-69
-
-
Lambros, M.P.1
Rahman, Y.E.2
-
34
-
-
0038101243
-
Interactions of cyclosporin a with phospholipid membranes: Effect of cholesterol
-
Soderlund, T., Lehtonen, J.Y.A. and Kinnunen, P.K.J. Interactions of cyclosporin A with phospholipid membranes: effect of cholesterol. Mol. Pharmacol. 55 (1999) 32-38. (Pubitemid 29042519)
-
(1999)
Molecular Pharmacology
, vol.55
, Issue.1
, pp. 32-38
-
-
Soderlund, T.1
Lehtonen, J.Y.A.2
Kinnunen, P.K.J.3
-
35
-
-
0025278198
-
Interaction of cyclosporin a with dipalmitoylphosphatidylcholine
-
Wiedmann, T.S., Trouard, T., Shekar, S.C., Polikandritou, M. and Rahman, Y.E. Interaction of cyclosporin A with dipalmitoylphosphatidylcholine. Biochim. Biophys. Acta 1023 (1990) 12-18.
-
(1990)
Biochim. Biophys. Acta
, vol.1023
, pp. 12-18
-
-
Wiedmann, T.S.1
Trouard, T.2
Shekar, S.C.3
Polikandritou, M.4
Rahman, Y.E.5
-
36
-
-
0025800438
-
Liposomes as cyclosporin a carriers: The influence of ordering of hydrocarbon chains of phosphatidylglycerol liposomes on the association with and topography of cyclosporin a
-
Stuhne-Sekalec, L. and Stanacev, N.Z. Liposomes as cyclosporin A carriers: the influence of ordering of hydrocarbon chains of phosphatidylglycerol liposomes on the association with and topography of cyclosporin A. J. Microencapsul. 8 (1991) 283-294.
-
(1991)
J. Microencapsul.
, vol.8
, pp. 283-294
-
-
Stuhne-Sekalec, L.1
Stanacev, N.Z.2
-
37
-
-
0028281419
-
The increased efficacy and decreased nephrotoxicity of a cyclosporine liposome
-
Freise, C.E., Liu, T., Hong, K.L., Osorio, R.W., Papahadjopoulos, D., Ferrell, L., Ascher, N.L. and Roberts, J.P. The increased efficacy and decreased nephrotoxicity of a cyclosporine liposome. Transplantation 57 (1994) 928-932. (Pubitemid 24114689)
-
(1994)
Transplantation
, vol.57
, Issue.6
, pp. 928-932
-
-
Freise, C.E.1
Liu, T.2
Hong, K.3
Osorio, R.W.4
Papahadjopoulos, D.5
Ferrell, L.6
Ascher, N.L.7
Roberts, J.P.8
-
38
-
-
0022627174
-
Acutely impaired renal function during intravenous administration of cyclosporine A: A cremophore side-effect
-
Thiel, G., Hermle, M. and Brunner, F.P. Acutely impaired renal function during intravenous administration of cyclosporine A: a cremophor sideeffect. Clin. Nephrol. 25 (1986) S40-S42. (Pubitemid 16114278)
-
(1986)
Clinical Nephrology
, vol.25
, Issue.SUPPL. 1
-
-
Thiel, G.1
Hermle, M.2
Brunner, F.P.3
-
39
-
-
0028924772
-
Characterization, stability and in vivo targeting of liposomal formulations containing cyclosporine
-
Alangary, A.A., Bayomi, M.A., Khidr, S.N., Almeshal, M.A. and Aldardiri, M. Characterization, stability and in vivo targeting of liposomal formulations containing cyclosporine. Int. J. Pharm. 114 (1995) 221-225.
-
(1995)
Int. J. Pharm.
, vol.114
, pp. 221-225
-
-
Alangary, A.A.1
Bayomi, M.A.2
Khidr, S.N.3
Almeshal, M.A.4
Aldardiri, M.5
-
40
-
-
0028948839
-
A theoretical basis for a biopharmaceutical drug classification: The correlation of in vitro drug product dissolution and in vivo bioavailability
-
Amidon, G.L., Lennernas, H., Shah, V.P. and Crison, J.R. A theoretical basis for a biopharmaceutical drug classification: the correlation of in vitro drug product dissolution and in vivo bioavailability. Pharm. Res. 12 (1995) 413-420.
-
(1995)
Pharm. Res.
, vol.12
, pp. 413-420
-
-
Amidon, G.L.1
Lennernas, H.2
Shah, V.P.3
Crison, J.R.4
-
41
-
-
0030003789
-
Estimation of the increase in solubility of drugs as a function of bile salt concentration
-
DOI 10.1023/A:1016062224568
-
Mithani, S.D., Bakatselou, V., TenHoor, C.N. and Dressman, J.B. Estimation of the increase in solubility of drugs as a function of bile salt concentration. Pharm. Res. 13 (1996) 163-167. (Pubitemid 26076314)
-
(1996)
Pharmaceutical Research
, vol.13
, Issue.1
, pp. 163-167
-
-
Mithani, S.D.1
Bakatselou, V.2
Tenhoor, C.N.3
Dressman, J.B.4
-
42
-
-
0028820208
-
Differentiation of absorption and first-pass gut and hepatic metabolism in humans: Studies with cyclosporine
-
Wu, C.Y., Benet, L.Z., Hebert, M.F., Gupta, S.K., Rowland, M., Gomez, D.Y. and Wacher, V.J. Differentiation of absorption and first-pass gut and hepatic metabolism in humans: Studies with cyclosporine. Clin. Pharmacol. Ther. 58 (1995) 492-497.
-
(1995)
Clin. Pharmacol. Ther.
, vol.58
, pp. 492-497
-
-
Wu, C.Y.1
Benet, L.Z.2
Hebert, M.F.3
Gupta, S.K.4
Rowland, M.5
Gomez, D.Y.6
Wacher, V.J.7
-
43
-
-
0033511898
-
Metabolism of cyclosporine by cytochromes P450 3A9 and 3A4
-
Kelly, P.A., Wang, H., Napoli, K.L., Kahan, B.D. and Strobel, H.W. Metabolism of cyclosporine by cytochromes P450 3A9 and 3A4. Eur. J. Drug Metab. Pharmacokinet. 24 (1999) 321-328. (Pubitemid 30342700)
-
(1999)
European Journal of Drug Metabolism and Pharmacokinetics
, vol.24
, Issue.4
, pp. 321-328
-
-
Kelly, P.A.1
Wang, H.2
Napoli, K.L.3
Kahan, B.D.4
Strobel, H.W.5
-
44
-
-
0343416856
-
Contributions of hepatic and intestinal metabolism and Pglycoprotein to cyclosporine and tacrolimus oral drug delivery
-
Hebert, M.F. Contributions of hepatic and intestinal metabolism and Pglycoprotein to cyclosporine and tacrolimus oral drug delivery. Adv. Drug. Deliv. Rev. 27 (1997) 201-214.
-
(1997)
Adv. Drug. Deliv. Rev.
, vol.27
, pp. 201-214
-
-
Hebert, M.F.1
-
45
-
-
0029986277
-
Relevance of p-glycoprotein for the enteral absorption of cyclosporin A: In vitro-in vivo correlation
-
Fricker, G., Drewe, J., Huwyler, J., Gutmann, H. and Beglinger, C. Relevance of p-glycoprotein for the enteral absorption of cyclosporin A: in vitro in vivo correlation. Br. J. Pharmacol. 118 (1996) 1841-1847. (Pubitemid 26252682)
-
(1996)
British Journal of Pharmacology
, vol.118
, Issue.7
, pp. 1841-1847
-
-
Fricker, G.1
Drewe, J.2
Huwyler, J.3
Gutmann, H.4
Beglinger, C.5
-
46
-
-
12644272784
-
Role of intestinal P-glycoprotein (mdr1) in interpatient variation in the oral bioavailability of cyclosporine
-
DOI 10.1016/S0009-9236(97)90027-8
-
Lown, K.S., Mayo, R.R., Leichtman, A.B., Hsiao, H.L., Turgeon, D.K., Schmiedlin-Ren, P., Brown, M.B., Guo, W., Rossi, S.J., Benet, L.Z. and Watkins, P.B. Role of intestinal P- glycoprotein (mdr1) in interpatient variation in the oral bioavailability of cyclosporine. Clin. Pharmacol. Ther. 62 (1997) 248-260. (Pubitemid 27417790)
-
(1997)
Clinical Pharmacology and Therapeutics
, vol.62
, Issue.3
, pp. 248-260
-
-
Lown, K.S.1
Mayo, R.R.2
Leichtman, A.B.3
Hsiao, H.-L.4
Turgeon, D.K.5
Schmiedlin-Ren, P.6
Brown, M.B.7
Guo, W.8
Rossi, S.J.9
Benet, L.Z.10
Watkins, P.B.11
-
47
-
-
0022931552
-
The efect of vehicle on the oral absorption of cyclosporin
-
Johnston, A., Marsden, J.T., Hla, K.K., Henry, J.A. and Holt, D.W. The effect of vehicle on oral absorption of cyclosporin. Br. J. Clin. Pharmacol. 21 (1986) 331-333. (Pubitemid 17168706)
-
(1986)
British Journal of Clinical Pharmacology
, vol.21
, Issue.3
, pp. 331-333
-
-
Johnston, A.1
Marsden, J.T.2
Hla, K.K.3
-
48
-
-
0028335905
-
Reduced inter- And intraindividual variability in cyclosporine pharmacokinetics from a microemulsion formulation
-
DOI 10.1002/jps.2600830336
-
Kovarik, J.M., Mueller, E.A., van Bree, J.B., Tetzloff, W. and Kutz, K. Reduced inter- and intraindividual variability in cyclosporine pharmacokinetics from a microemulsion formulation. J. Pharm. Sci. 83 (1994) 444-446. (Pubitemid 24224228)
-
(1994)
Journal of Pharmaceutical Sciences
, vol.83
, Issue.3
, pp. 444-446
-
-
Kovarik, J.M.1
Mueller, E.A.2
Van Bree, J.B.3
Tetzloff, W.4
Kutz, K.5
-
49
-
-
0035238531
-
Cyclosporin. An updated review of the pharmacokinetic properties, clinical efficiacy and tolerability of a microemulsion-based formulation (Neoral® ) in organ transplantation
-
Dunn, C.J., Wagstaff, A.J., Perry, C.M., Plosker, G.L. and Goa, K.L. Cyclosporin. An updated review of the pharmacokinetic properties, clinical efficiacy and tolerability of a microemulsion-based formulation (Neoral® ) in organ transplantation. Drugs 61 (2001) 1957-2016.
-
(2001)
Drugs
, vol.61
, pp. 1957-2016
-
-
Dunn, C.J.1
Wagstaff, A.J.2
Perry, C.M.3
Plosker, G.L.4
Goa, K.L.5
-
50
-
-
20444475424
-
Generic cyclosporine formulations: More open questions than answers
-
DOI 10.1111/j.1432-2277.2005.00078.x
-
Cattaneo, D., Perico, N. and Remuzzi, G. Generic cyclosporine formulations: more open questions than answers. Transpl. Int. 18 (2005) 371-378. (Pubitemid 41726869)
-
(2005)
Transplant International
, vol.18
, Issue.4
, pp. 371-378
-
-
Cattaneo, D.1
Perico, N.2
Remuzzi, G.3
-
51
-
-
0038045086
-
A pharmacokinetic and clinical review of the potential clinical impact of using different formulations of cyclosporin a
-
DOI 10.1016/S0149-2918(03)80161-3
-
Pollard, S., Nashan, B., Johnston, A., Hoyer, P., Belitsky, P., Keown, P. and Helderman, H. A pharmacokinetic and clinical review of the potential clinical impact of using different formulations of cyclosporin A. Clin. Ther. 25 (2003) 1654-1669. (Pubitemid 36801940)
-
(2003)
Clinical Therapeutics
, vol.25
, Issue.6
, pp. 1654-1669
-
-
Pollard, S.1
Nashan, B.2
Johnston, A.3
Hoyer, P.4
Belitsky, P.5
Keown, P.6
Helderman, H.7
-
52
-
-
0025220388
-
Pharmacokinetics of two alternative dosage forms for cyclosporine: Liposomes and intralipid
-
Venkataram, S., Awni, W.M., Jordan, K. and Rahman, Y.E. Pharmacokinetics of two alternative dosage forms for cyclosporine: liposomes and intralipid. J. Pharm. Sci. 79 (1990) 216-219. (Pubitemid 20146485)
-
(1990)
Journal of Pharmaceutical Sciences
, vol.79
, Issue.3
, pp. 216-219
-
-
Venkataram, S.1
Awni, W.M.2
Jordan, K.3
Rahman, Y.E.4
-
53
-
-
0027259027
-
Stability of liposomes in vitro and their uptake by rat Peyer's patches following oral administration
-
DOI 10.1023/A:1018936806278
-
Aramaki, Y., Tomizawa, H., Hara, T., Yachi, K., Kikuchi, H. and Tsuchiya, S. Stability of liposomes in vitro and their uptake by rat Peyer's patches following oral administration. Pharm. Res. 10 (1993) 1228-1231. (Pubitemid 23244182)
-
(1993)
Pharmaceutical Research
, vol.10
, Issue.8
, pp. 1228-1231
-
-
Aramaki, Y.1
Tomizawa, H.2
Hara, T.3
Yachi, K.4
Kikuchi, H.5
Tsuchiya, S.6
-
54
-
-
0035937507
-
Pharmacokinetic behavior of cyclosporin a in rabbits by oral administration of lecithin vesicle and sandimmun neoral
-
DOI 10.1016/S0378-5173(00)00680-3, PII S0378517300006803
-
Guo, J., Ping, Q. and Chen, Y. Pharmacokinetic behavior of cyclosporin A in rabbits by oral administration of lecithin vesicle and sandimmun neoral. Int. J. Pharm. 216 (2001) 17-21. (Pubitemid 32232090)
-
(2001)
International Journal of Pharmaceutics
, vol.216
, Issue.1-2
, pp. 17-21
-
-
Guo, J.1
Ping, Q.2
Chen, Y.3
-
55
-
-
33750069158
-
Preparation, characterization and in vivo studies of proliposomes containing cyclosporine a
-
DOI 10.1166/jnn.2006.403
-
Shah, N.M., Parikh, J., Namdeo, A., Subramanian, N. and Bhowmick, S. Preparation, characterization and in vivo studies of proliposomes containing Cyclosporine A. J. Nanosci. Nanotechnol. 6 (2006) 2967-2973. (Pubitemid 44579969)
-
(2006)
Journal of Nanoscience and Nanotechnology
, vol.6
, Issue.9-10
, pp. 2967-2973
-
-
Shah, N.M.1
Parikh, J.2
Namdeo, A.3
Subramanian, N.4
Bhowmick, S.5
-
56
-
-
0032526501
-
Oral administration of liposomes containing cyclosporine: A pharmacokinetic study
-
Al-Meshal, M.A., Khidr, S.H., Bayomi, M.A. and Al-Angary, A.A. Oral administration of liposomes containing cyclosporine: a pharmacokinetic study. Int. J. Pharm. 168 (1998) 163-168.
-
(1998)
Int. J. Pharm.
, vol.168
, pp. 163-168
-
-
Al-Meshal, M.A.1
Khidr, S.H.2
Bayomi, M.A.3
Al-Angary, A.A.4
-
57
-
-
0036805875
-
Improved oral bioavailability of cyclosporin a in male Wistar rats: Comparison of a Solutol HS 15 containing self-dispersing formulation and a microsuspension
-
DOI 10.1016/S0378-5173(02)00339-3, PII S0378517302003393
-
Bravo Gonzalez, R.C., Huwyler, J., Walter, I., Mountfield, R. and Bittner, B. Improved oral bioavailability of cyclosporin A in male Wistar rats. Comparison of a Solutol HS 15 containing self-dispersing formulation and a microsuspension. Int. J. Pharm. 245 (2002) 143-151. (Pubitemid 35299900)
-
(2002)
International Journal of Pharmaceutics
, vol.245
, Issue.1-2
, pp. 143-151
-
-
Bravo Gonzalez, R.C.1
Huwyler, J.2
Walter, I.3
Mountfield, R.4
Bittner, B.5
-
58
-
-
23444460408
-
Novel gels and their dispersions - Oral drug delivery systems for ciclosporin
-
DOI 10.1016/j.ijpharm.2005.06.002, PII S0378517305003303
-
Murdan, S., Andrysek, T. and Son, D. Novel gels and their dispersions - oral drug delivery systems for ciclosporin. Int. J. Pharm. 300 (2005) 113-124. (Pubitemid 41112173)
-
(2005)
International Journal of Pharmaceutics
, vol.300
, Issue.1-2
, pp. 113-124
-
-
Murdan, S.1
Andrysek, T.2
Son, D.3
-
59
-
-
0037027847
-
Pharmacokinetic and pharmacodynamic evaluation of cyclosporin a O/W-emulsion in rats
-
Kim, S.J., Choi, H.K. and Lee, Y.B. Pharmacokinetic and pharmacodynamic evaluation of cyclosporin A O/W-emulsion in rats. Int. J. Pharm. 249 (2002) 149-156.
-
(2002)
Int. J. Pharm.
, vol.249
, pp. 149-156
-
-
Kim, S.J.1
Choi, H.K.2
Lee, Y.B.3
-
60
-
-
0035984944
-
Pharmacokinetic and pharmacodynamic evaluation of cyclosporin a O/W-emulsion and microsphere formulations in rabbits
-
DOI 10.1016/S0928-0987(02)00048-9, PII S0928098702000489
-
Kim, S.J., Choi, H.K., Suh, S.P. and Lee, Y.B. Pharmacokinetic and pharmacodynamic evaluation of cyclosporin A O/W-emulsion and microsphere formulations in rabbits. Eur. J. Pharm. Sci. 15 (2002) 497-502. (Pubitemid 34567106)
-
(2002)
European Journal of Pharmaceutical Sciences
, vol.15
, Issue.5
, pp. 497-502
-
-
Kim, S.-J.1
Choi, H.-K.2
Suh, S.-P.3
Lee, Y.-B.4
-
61
-
-
36048934949
-
Development of cyclosporin A-loaded hyaluronic microsphere with enhanced oral bioavailability
-
DOI 10.1016/j.ijpharm.2007.08.050, PII S037851730700748X
-
Woo, J.S., Piao, M.G., Li, D.X., Ryu, D.S., Choi, J.Y., Kim, J.A., Kim, J.H., Jin, S.G., Kim, D.D., Lyoo, W.S., Yong, C.S. and Choi, H.G. Development of cyclosporin A-loaded hyaluronic microsphere with enhanced oral bioavailability. Int. J. Pharm. 345 (2007) 134-141. (Pubitemid 350087552)
-
(2007)
International Journal of Pharmaceutics
, vol.345
, Issue.1-2
, pp. 134-141
-
-
Woo, J.S.1
Piao, M.G.2
Li, D.X.3
Ryu, D.-S.4
Choi, J.Y.5
Kim, J.-A.6
Kim, J.H.7
Jin, S.G.8
Kim, D.-D.9
Lyoo, W.S.10
Yong, C.S.11
Choi, H.-G.12
-
62
-
-
0035821352
-
Bioavailibility of cyclosporin a dispersed in sodium lauryl sulfate-dextrin based solid microspheres
-
Lee, E.J., Lee, S.W., Choi, H.G. and Kim, C.K. Bioavailibility of cyclosporin A dispersed in sodium lauryl sulfate-dextrin based solid microspheres. Int. J. Pharm. 218 (2001) 125-131.
-
(2001)
Int. J. Pharm.
, vol.218
, pp. 125-131
-
-
Lee, E.J.1
Lee, S.W.2
Choi, H.G.3
Kim, C.K.4
-
63
-
-
0034630960
-
Studies on the cyclosporin a loaded stearic acid nanoparticles
-
DOI 10.1016/S0378-5173(00)00361-6, PII S0378517300003616
-
Zhang, Q., Yie, G., Li, Y., Yang, Q. and Nagai, T. Studies on the cyclosporin A loaded stearic acid nanoparticles. Int. J. Pharm. 200 (2000) 153-159. (Pubitemid 30364902)
-
(2000)
International Journal of Pharmaceutics
, vol.200
, Issue.2
, pp. 153-159
-
-
Zhang, Q.1
Yie, G.2
Li, Y.3
Yang, Q.4
Nagai, T.5
-
64
-
-
16844369855
-
Engineering polysaccharide-based polymeric micelles to enhance permeability of cyclosporin a across Caco-2 cells
-
DOI 10.1007/s11095-004-1188-0
-
Francis, M.F., Cristea, M., Yang, Y. and Winnik, F.M. Engineering polysaccharide-based polymeric micelles to enhance permeability of cyclosporin A across Caco-2 cells. Pharm. Res. 22 (2005) 209-219. (Pubitemid 40487204)
-
(2005)
Pharmaceutical Research
, vol.22
, Issue.2
, pp. 209-219
-
-
Francis, M.F.1
Cristea, M.2
Yang, Y.3
Winnik, F.M.4
-
65
-
-
0037028069
-
Investigation of the factors influencing the release rates of cyclosporin A-loaded micro- And nanoparticles prepared by high-pressure homogenizer
-
DOI 10.1016/S0168-3659(02)00239-0, PII S0168365902002390
-
Lee, W.K., Park, J.Y., Yang, E.H., Suh, H., Kim, S.H., Chung, D.S., Choi, K., Yang, C.W. and Park, J.S. Investigation of the factors influencing the release rates of cyclosporin A-loaded micro- and nanoparticles prepared by high-pressure homogenizer. J. Control. Release 84 (2002) 115-123. (Pubitemid 35435316)
-
(2002)
Journal of Controlled Release
, vol.84
, Issue.3
, pp. 115-123
-
-
Lee, W.-K.1
Park, J.-Y.2
Yang, E.H.3
Suh, H.4
Kim, S.H.5
Chung, D.S.6
Choi, K.7
Yang, C.W.8
Park, J.-S.9
-
66
-
-
34249087392
-
PLGA nanoparticles for oral delivery of cyclosporine: Nephrotoxicity and pharmacokinetic studies in comparison to Sandimmune Neoral
-
DOI 10.1016/j.jconrel.2007.02.004, PII S0168365907000788
-
Italia, J.L., Bhatt, D.K., Bhardwaj, V., Tikoo, K. and Kumar, M.N. PLGA nanoparticles for oral delivery of cyclosporine: nephrotoxicity and pharmacokinetic studies in comparison to Sandimmune Neoral. J. Control. Release 119 (2007) 197-206. (Pubitemid 46778760)
-
(2007)
Journal of Controlled Release
, vol.119
, Issue.2
, pp. 197-206
-
-
Italia, J.L.1
Bhatt, D.K.2
Bhardwaj, V.3
Tikoo, K.4
Kumar, M.N.V.R.5
-
67
-
-
0035134749
-
Development and characterization of CyA-loaded poly(lactic acid)-poly(ethylene glycol)PEG micro- And nanoparticles. Comparison with conventional PLA particulate carriers
-
DOI 10.1016/S0939-6411(00)00143-0, PII S0939641100001430
-
Gref, R., Quellec, P., Sanchez, A., Calvo, P., Dellacherie, E. and Alonso, M.J. Development and characterization of CyA-loaded poly(lactic acid)- poly(ethylene glycol)PEG micro- and nanoparticles. Comparison with conventional PLA particulate carriers. Eur. J. Pharm. Biopharm. 51 (2001) 111-118. (Pubitemid 32162489)
-
(2001)
European Journal of Pharmaceutics and Biopharmaceutics
, vol.51
, Issue.2
, pp. 111-118
-
-
Gref, R.1
Quellec, P.2
Sanchez, A.3
Calvo, P.4
Dellacherie, E.5
Alonso, M.J.6
-
68
-
-
0032850436
-
A polycaprolactone nanoparticle formulation of cyclosporin-a improves the prediction of area under the curve using a limited sampling strategy
-
DOI 10.1016/S0378-5173(99)00177-5, PII S0378517399001775
-
Molpeceres, J., Chacón, M., Guzmán, M., Berges, L. and del Rosario Aberturas, M. A polycaprolactone nanoparticle formulation of cyclosporine improves the prediction of area under the curve using a limited sampling strategy. Int. J. Pharm. 187 (1999) 101-113. (Pubitemid 29435977)
-
(1999)
International Journal of Pharmaceutics
, vol.187
, Issue.1
, pp. 101-113
-
-
Molpeceres, J.1
Chacon, M.2
Guzman, M.3
Berges, L.4
Del Rosario Aberturas, M.5
-
69
-
-
0035101280
-
Cyclosporine-loaded polycaprolactone nanoparticles: Immunosuppression and nephrotoxicity in rats
-
DOI 10.1016/S0928-0987(00)00198-6, PII S0928098700001986
-
Varela, M.C., Guzman, M., Molpeceres, J., del Rosario Aberturas, M., Rodriguez-Puyol, D. and Rodriguez-Puyol, M. Cyclosporine-loaded polycaprolactone nanoparticles: immunosuppression and nephrotoxicity in rats. Eur. J. Pharm. Sci. 12 (2001) 471-478. (Pubitemid 32166746)
-
(2001)
European Journal of Pharmaceutical Sciences
, vol.12
, Issue.4
, pp. 471-478
-
-
Carmen Varela, M.1
Guzman, M.2
Molpeceres, J.3
Del Rosario Aberturas, M.4
Rodriguez-Puyol, D.5
Rodriguez-Puyol, M.6
-
70
-
-
3242673239
-
PH-sensitive nanoparticles for improving the oral bioavailability of cyclosporine a
-
DOI 10.1016/j.ijpharm.2004.05.006, PII S0378517304002893
-
Dai, J., Nagai, T., Wang, X., Zhang, T., Meng, M. and Zhang, Q. pH-sensitive nanoparticles for improving the oral bioavailability of cyclosporine A. Int. J. Pharm. 280 (2004) 229-240. (Pubitemid 38950919)
-
(2004)
International Journal of Pharmaceutics
, vol.280
, Issue.1-2
, pp. 229-240
-
-
Dai, J.1
Nagai, T.2
Wang, X.3
Zhang, T.4
Meng, M.5
Zhang, Q.6
-
71
-
-
33748288343
-
Long-term studies on the stability and oral bioavailability of cyclosporine a nanoparticle colloid
-
DOI 10.1016/j.ijpharm.2006.05.021, PII S0378517306003887
-
Wang, X.Q., Huang, J., Dai, J.D., Zhang, T., Lu, W.L., Zhang, H., Zhang, X., Wang, J.C. and Zhang, Q. Long-term studies on the stability and oral bioavailibility of cyclosporine A nanoparticle colloid. Int. J. Pharm. 322 (2006) 146-153. (Pubitemid 44331520)
-
(2006)
International Journal of Pharmaceutics
, vol.322
, Issue.1-2
, pp. 146-153
-
-
Wang, X.-Q.1
Huang, J.2
Dai, J.-D.3
Zhang, T.4
Lu, W.-L.5
Zhang, H.6
Zhang, X.7
Wang, J.-C.8
Zhang, Q.9
-
72
-
-
3042551382
-
Bioavailability and pharmacokinetics of cyclosporine A-loaded pH-sensitive nanoparticles for oral administration
-
DOI 10.1016/j.jconrel.2004.03.003, PII S016836590400121X
-
Wang, X.Q.W., Dai, J.D., Chen, Z., Zhang, T., Xia, G.M., Nagai, T. and Zhang, Q. Bioavailability and pharmacokinetics of cyclosporine A-loaded pH-sensitive nanoparticles for oral administration. J. Control Release 97 (2004) 421-429. (Pubitemid 38802944)
-
(2004)
Journal of Controlled Release
, vol.97
, Issue.3
, pp. 421-429
-
-
Wang, X.-Q.1
Dai, J.-D.2
Chen, Z.3
Zhang, T.4
Xia, G.-M.5
Nagai, T.6
Zhang, Q.7
-
73
-
-
0037027833
-
Positively charged nanoparticles for improving the oral bioavailability of cyclosporin-A
-
DOI 10.1016/S0378-5173(02)00461-1, PII S0378517302004611
-
El-Shabouri, M.H. Positively charged nanoparticles for improving the oral bioavailability of cyclosporin-A. Int. J. Pharm. 249 (2002) 101-108. (Pubitemid 35333436)
-
(2002)
International Journal of Pharmaceutics
, vol.249
, Issue.1-2
, pp. 101-108
-
-
El-Shabouri, M.H.1
-
74
-
-
33744552970
-
Polyelectrolyte nanoparticles with high drug loading enhance the oral uptake of hydrophobic compounds
-
DOI 10.1021/bm060130l
-
Cheng, W.P., Gray, A.I., Tetley, L., Hang Tle, B., Schätzlein, A.G. and Uchegbu, I.F. Polyelectrolyte nanoparticles with high drug loading enhance the oral uptake of hydrophobic compounds. Biomacromolecules 7 (2006) 1509-1520. (Pubitemid 43811207)
-
(2006)
Biomacromolecules
, vol.7
, Issue.5
, pp. 1509-1520
-
-
Cheng, W.P.1
Gray, A.I.2
Tetley, L.3
Hang, T.L.B.4
Schatzlein, A.G.5
Uchegbu, I.F.6
-
75
-
-
33748077089
-
Enhancement of dissolution of cyclosporine a using solid dispersions with polyoxyethylene (40) stearate
-
Liu, C., Zhu, S.J., Zhou, Y., Wei, Y.P. and Pei, Y.Y. Enhancement of dissolution of cyclosporine A using solid dispersions with polyoxyethylene (40) stearate. Pharmazie 61 (2006) 681-684. (Pubitemid 44298923)
-
(2006)
Pharmazie
, vol.61
, Issue.8
, pp. 681-684
-
-
Liu, C.1
Zhu, S.J.2
Zhou, Y.3
Wei, Y.P.4
Pei, Y.-Y.5
-
76
-
-
32344439711
-
Enhancing the bioavailability of cyclosporine a using solid dispersion containing polyoxyethylene (40) stearate
-
DOI 10.1080/03639040500388573, PII M3T47T50KR770668
-
Liu, C., Wu, J., Shi, B., Zhang, Y., Gao, T. and Pei, Y. Enhancing the bioavailability of cyclosporine a using solid dispersion containing polyoxyethylene (40) stearate. Drug Dev. Ind. Pharm. 32 (2006) 115-123. (Pubitemid 43220920)
-
(2006)
Drug Development and Industrial Pharmacy
, vol.32
, Issue.1
, pp. 115-123
-
-
Liu, C.1
Wu, J.2
Shi, B.3
Zhang, Y.4
Gao, T.5
Pei, Y.6
-
77
-
-
39849097998
-
®): Drug-lipid physicochemical interactions and characterization of drug incorporation
-
DOI 10.1016/j.ejpb.2007.07.006, PII S0939641107002603
-
Mueller, R.H., Runge, S.A., Ravelli, V., Thunemann, A.F., Mehnert, W. and Souto, E.B. Cyclosporine-loaded solid lipid nanoparticles (SLN® ): Druglipid physicochemical interactions and characterization of drug incorporation. Eur. J. Pharm. Biopharm. 68 (2008) 535-544. (Pubitemid 351318197)
-
(2008)
European Journal of Pharmaceutics and Biopharmaceutics
, vol.68
, Issue.3
, pp. 535-544
-
-
Muller, R.H.1
Runge, S.A.2
Ravelli, V.3
Thunemann, A.F.4
Mehnert, W.5
Souto, E.B.6
-
78
-
-
1942498889
-
Cyclosporin Nanoparticulate Lipospheres for Oral Administration
-
DOI 10.1002/jps.20057
-
Bekerman, T., Golenser, J. and Domb, A. Cyclosporin nanoparticulate lipospheres for oral administration. J. Pharm. Sci. 93 (2004) 1264-1270. (Pubitemid 38529699)
-
(2004)
Journal of Pharmaceutical Sciences
, vol.93
, Issue.5
, pp. 1264-1270
-
-
Bekerman, T.1
Golenser, J.2
Domb, A.3
-
79
-
-
1442334238
-
Incorporation of lipophilic drugs in sugar glasses by lyophilization using a mixture of water and tertiary butyl alcohol as solvent
-
Van Drooge, D.J., Hinrichs, W.L. and Frijlink, H.W. Incorporation of lipophilic drugs in sugar glasses by lyophilization using a mixture of water and tertiary butyl alcohol as solvent. J. Pharm. Sci. 93 (2004) 713-725.
-
(2004)
J. Pharm. Sci.
, vol.93
, pp. 713-725
-
-
Van Drooge, D.J.1
Hinrichs, W.L.2
Frijlink, H.W.3
-
80
-
-
0033039631
-
Enhanced absorption of cyclosporin a by complexation with dimethyl-beta Cyclodextrin in bile duct-cannulated and -noncannulated rats
-
Miyake, K., Arima, H., Irie, T., Hirayama, F. and Uekama, K. Enhanced absorption of cyclosporin A by complexation with dimethyl-betacyclodextrin in bile duct-cannulated and -noncannulated rats. Biol. Pharm. Bull. 22 (1999) 66-72. (Pubitemid 29081060)
-
(1999)
Biological and Pharmaceutical Bulletin
, vol.22
, Issue.1
, pp. 66-72
-
-
Miyake, K.1
Arima, H.2
Irie, T.3
Hirayama, F.4
Uekama, K.5
-
81
-
-
27744448891
-
Absorption enhancement, mechanistic and toxicity studies of medium chain fatty acids, cyclodextrins and bile salts as peroral absorption enhancers
-
DOI 10.1016/j.farmac.2005.08.008, PII S0014827X05001874
-
Sharma, P., Varma, M.V.S., Chwala, H.P.S. and Panchagnula, R. Absorption enhancement, mechanistic and toxicity studies of medium chain fatty acids, cyclodextrins and bile salts as peroral absorption enhancers. Il Farmaco 60 (2005) 884-893. (Pubitemid 41586262)
-
(2005)
Farmaco
, vol.60
, Issue.11-12
, pp. 884-893
-
-
Sharma, P.1
Varma, M.V.S.2
Chawla, H.P.S.3
Panchagnula, R.4
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