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Volumn 34, Issue 11, 2011, Pages 1887-1897

Designing micro- and nano-particles for treating rheumatoid arthritis

Author keywords

Drug carriers; Microparticles; Nanoparticles; Rheumatoid arthritis; Shape; Size; Surface chemistry; Targeted drug delivery

Indexed keywords

ABATACEPT; ACETYLSALICYLIC ACID; ADALIMUMAB; BETAMETHASONE; CELECOXIB; CHITOSAN; DEXAMETHASONE; ETANERCEPT; FOLATE RECEPTOR 2; GOLD SALT; GOLIMUMAB; HYDROXYCHLOROQUINE; IBUPROFEN; INFLIXIMAB; LEFLUNOMIDE; LIPOSOME; METHOTREXATE; NANOPARTICLE; NAPROXEN; POLYCAPROLACTONE; POLYGLACTIN; POLYLACTIC ACID; PREDNISOLONE; PREDNISOLONE SODIUM PHOSPHATE; PREDNISONE; RECOMBINANT INTERLEUKIN 1 RECEPTOR BLOCKING AGENT; RITUXIMAB; SALAZOSULFAPYRIDINE; TOCILIZUMAB; TUMOR NECROSIS FACTOR INHIBITOR;

EID: 83655211421     PISSN: 02536269     EISSN: 19763786     Source Type: Journal    
DOI: 10.1007/s12272-011-1109-9     Document Type: Review
Times cited : (84)

References (85)
  • 1
    • 38149100039 scopus 로고    scopus 로고
    • Amphipathic weak acid glucocorticoid prodrugs remote loaded into sterically stabilized nanoliposomes evaluated in arthritic rats and in a Beagle dog: A novel approach to treating autoimmune arthritis
    • 18163482 10.1002/art.23230 1:CAS:528:DC%2BD1cXhslOjtrs%3D
    • Y. Avnir R. Ulmansky V. Wasserman S. Even Chen M. Broyer Y. Barenholz Y. Naparstek 2008 Amphipathic weak acid glucocorticoid prodrugs remote loaded into sterically stabilized nanoliposomes evaluated in arthritic rats and in a Beagle dog: A novel approach to treating autoimmune arthritis Arthritis Rheum. 58 119 129 18163482 10.1002/art.23230 1:CAS:528:DC%2BD1cXhslOjtrs%3D
    • (2008) Arthritis Rheum. , vol.58 , pp. 119-129
    • Avnir, Y.1    Ulmansky, R.2    Wasserman, V.3    Even Chen, S.4    Broyer, M.5    Barenholz, Y.6    Naparstek, Y.7
  • 2
    • 58849124775 scopus 로고    scopus 로고
    • Dexamethasone-containing PLGA superparamagnetic microparticles as carriers for the local treatment of arthritis
    • 19135244 10.1016/j.biomaterials.2008.12.017 1:CAS:528: DC%2BD1MXht1ejsLg%3D
    • N. Butoescu C. A. Seemayer M. Foti O. Jordan E. Doelker 2009 Dexamethasone-containing PLGA superparamagnetic microparticles as carriers for the local treatment of arthritis Biomaterials 30 1772 1780 19135244 10.1016/j.biomaterials.2008.12.017 1:CAS:528:DC%2BD1MXht1ejsLg%3D
    • (2009) Biomaterials , vol.30 , pp. 1772-1780
    • Butoescu, N.1    Seemayer, C.A.2    Foti, M.3    Jordan, O.4    Doelker, E.5
  • 3
    • 33645533255 scopus 로고    scopus 로고
    • Role of target geometry in phagocytosis
    • 16549762 10.1073/pnas.0600997103 1:CAS:528:DC%2BD28XjsVGls70%3D
    • J. A. Champion S. Mitragotri 2006 Role of target geometry in phagocytosis Proc. Natl. Acad. Sci. U. S. A. 103 4930 4934 16549762 10.1073/pnas.0600997103 1:CAS:528:DC%2BD28XjsVGls70%3D
    • (2006) Proc. Natl. Acad. Sci. U. S. A. , vol.103 , pp. 4930-4934
    • Champion, J.A.1    Mitragotri, S.2
  • 4
    • 34547178393 scopus 로고    scopus 로고
    • Particle shape: A new design parameter for micro- and nanoscale drug delivery carriers
    • DOI 10.1016/j.jconrel.2007.03.022, PII S0168365907001769
    • J. A. Champion Y. K. Katare S. Mitragotri 2007 Particle shape: a new design parameter for micro- and nanoscale drug delivery carriers J. Control. Release 121 3 9 17544538 10.1016/j.jconrel.2007.03.022 1:CAS:528: DC%2BD2sXosFeksrw%3D (Pubitemid 47126059)
    • (2007) Journal of Controlled Release , vol.121 , Issue.1-2 , pp. 3-9
    • Champion, J.A.1    Katare, Y.K.2    Mitragotri, S.3
  • 5
    • 34250164628 scopus 로고    scopus 로고
    • Folate coupled poly(ethyleneglycol) conjugates of anionic poly(amidoamine) dendrimer for inflammatory tissue specific drug delivery
    • DOI 10.1002/jbm.a.31122
    • D. Chandrasekar R. Sistla F. J. Ahmad R. K. Khar P. V. Diwan 2007 Folate coupled poly(ethyleneglycol) conjugates of anionic poly(amidoamine) dendrimer for inflammatory tissue specific drug delivery J. Biomed. Mater. Res. A 82 92 103 17269145 (Pubitemid 46906494)
    • (2007) Journal of Biomedical Materials Research - Part A , vol.82 , Issue.1 , pp. 92-103
    • Chandrasekar, D.1    Sistla, R.2    Ahmad, F.J.3    Khar, R.K.4    Diwan, P.V.5
  • 6
    • 33646397592 scopus 로고    scopus 로고
    • Determining the size and shape dependence of gold nanoparticle uptake into mammalian cells
    • 16608261 10.1021/nl052396o 1:CAS:528:DC%2BD28XhvVCjsLk%3D
    • B. D. Chithrani A. A. Ghazani W. C. W. Chan 2006 Determining the size and shape dependence of gold nanoparticle uptake into mammalian cells Nano lett. 6 662 668 16608261 10.1021/nl052396o 1:CAS:528:DC%2BD28XhvVCjsLk%3D
    • (2006) Nano Lett. , vol.6 , pp. 662-668
    • Chithrani, B.D.1    Ghazani, A.A.2    Chan, W.C.W.3
  • 7
    • 70449169625 scopus 로고
    • Multi-centre controlled trial comparing cortisone acetate and acetyl salicylic acid in the long-term treatment of rheumatoid arthritis
    • 10.1136/ard.16.3.277
    • E. R. Council 1957 Multi-centre controlled trial comparing cortisone acetate and acetyl salicylic acid in the long-term treatment of rheumatoid arthritis Ann. Rheum. Dis. 16 277 289 10.1136/ard.16.3.277
    • (1957) Ann. Rheum. Dis. , vol.16 , pp. 277-289
    • Council, E.R.1
  • 8
    • 57749207052 scopus 로고    scopus 로고
    • Intravascular delivery of particulate systems: Does geometry really matter?
    • 18712584 10.1007/s11095-008-9697-x 1:CAS:528:DC%2BD1cXhsFSjsr7P
    • P. Decuzzi R. Pasqualini W. Arap M. Ferrari 2009 Intravascular delivery of particulate systems: does geometry really matter? Pharm. Res. 26 235 243 18712584 10.1007/s11095-008-9697-x 1:CAS:528:DC%2BD1cXhsFSjsr7P
    • (2009) Pharm. Res. , vol.26 , pp. 235-243
    • Decuzzi, P.1    Pasqualini, R.2    Arap, W.3    Ferrari, M.4
  • 9
    • 77955413581 scopus 로고    scopus 로고
    • Flow and adhesion of drug carriers in blood vessels depend on their shape: A study using model synthetic microvascular networks
    • 20385181 10.1016/j.jconrel.2010.04.007 1:CAS:528:DC%2BC3cXpvVSnsbw%3D
    • N. Doshi B. Prabhakarpandian A. Rea-Ramsey K. Pant S. Sundaram S. Mitragotri 2010 Flow and adhesion of drug carriers in blood vessels depend on their shape: a study using model synthetic microvascular networks J. Control. Release 146 196 200 20385181 10.1016/j.jconrel.2010.04.007 1:CAS:528: DC%2BC3cXpvVSnsbw%3D
    • (2010) J. Control. Release , vol.146 , pp. 196-200
    • Doshi, N.1    Prabhakarpandian, B.2    Rea-Ramsey, A.3    Pant, K.4    Sundaram, S.5    Mitragotri, S.6
  • 10
    • 48149100741 scopus 로고    scopus 로고
    • Comparison of methotrexate monotherapy with a combination of methotrexate and etanercept in active, early, moderate to severe rheumatoid arthritis (COMET): A randomised, double-blind, parallel treatment trial
    • 18635256 10.1016/S0140-6736(08)61000-4 1:CAS:528:DC%2BD1cXpt1GqtLY%3D
    • P. Emery F. C. Breedveld S. Hall P. Durez D. J. Chang D. Robertson A. Singh R. D. Pedersen A. S. Koenig B. Freundlich 2008 Comparison of methotrexate monotherapy with a combination of methotrexate and etanercept in active, early, moderate to severe rheumatoid arthritis (COMET): a randomised, double-blind, parallel treatment trial Lancet 372 375 382 18635256 10.1016/S0140-6736(08) 61000-4 1:CAS:528:DC%2BD1cXpt1GqtLY%3D
    • (2008) Lancet , vol.372 , pp. 375-382
    • Emery, P.1    Breedveld, F.C.2    Hall, S.3    Durez, P.4    Chang, D.J.5    Robertson, D.6    Singh, A.7    Pedersen, R.D.8    Koenig, A.S.9    Freundlich, B.10
  • 11
    • 0037261231 scopus 로고    scopus 로고
    • In vitro cellular handling and in vivo targeting of E-selectin-directed immunoconjugates and immunoliposomes used for drug delivery to inflamed endothelium
    • DOI 10.1023/A:1022298725165
    • M. Everts G. A. Koning R. J. Kok S. A. Asgeirsdottir D. Vestweber D. K. Meijer G. Storm G. Molema 2003 In vitro cellular handling and in vivo targeting of E-selectin-directed immunoconjugates and immunoliposomes used for drug delivery to inflamed endothelium Pharm. Res. 20 64 72 12608538 10.1023/A:1022298725165 1:CAS:528:DC%2BD3sXoslKhtg%3D%3D (Pubitemid 36152919)
    • (2003) Pharmaceutical Research , vol.20 , Issue.1 , pp. 64-72
    • Everts, M.1    Koning, G.A.2    Kok, R.J.3    Asgeirsdottir, S.A.4    Vestweber, D.5    Meijer, D.K.F.6    Storm, G.7    Molema, G.8
  • 12
    • 28444496349 scopus 로고    scopus 로고
    • In vivo tumor targeting of tumor necrosis factor-α-loaded stealth nanoparticles: Effect of MePEG molecular weight and particle size
    • DOI 10.1016/j.ejps.2005.08.002, PII S0928098705002472
    • C. Fang B. Shi Y. Y. Pei M. H. Hong J. Wu H. Z. Chen 2006 In vivo tumor targeting of tumor necrosis factoralpha-loaded stealth nanoparticles: effect of MePEG molecular weight and particle size Eur. J. Pharm. Sci. 27 27 36 16150582 10.1016/j.ejps.2005.08.002 1:CAS:528:DC%2BD2MXht1OntLfI (Pubitemid 41728252)
    • (2006) European Journal of Pharmaceutical Sciences , vol.27 , Issue.1 , pp. 27-36
    • Fang, C.1    Shi, B.2    Pei, Y.-Y.3    Hong, M.-H.4    Wu, J.5    Chen, H.-Z.6
  • 13
    • 47249153519 scopus 로고    scopus 로고
    • Role of cytokines in rheumatoid arthritis: An education in pathophysiology and therapeutics
    • DOI 10.1111/j.1600-065X.2008.00626.x
    • M. Feldmann S. R. N. Maini 2008 Role of cytokines in rheumatoid arthritis: an education in pathophysiology and therapeutics Immunol. Rev. 223 7 19 18613827 10.1111/j.1600-065X.2008.00626.x 1:CAS:528:DC%2BD1cXptlGlsrY%3D (Pubitemid 351986171)
    • (2008) Immunological Reviews , vol.223 , Issue.1 , pp. 7-19
    • Feldmann, M.1    Maini, S.R.N.2
  • 14
    • 0038011833 scopus 로고    scopus 로고
    • Evolving concepts of rheumatoid arthritis
    • DOI 10.1038/nature01661
    • G. S. Firestein 2003 Evolving concepts of rheumatoid arthritis Nature 423 356 361 12748655 10.1038/nature01661 1:CAS:528:DC%2BD3sXjs1ynu7c%3D (Pubitemid 40852711)
    • (2003) Nature , vol.423 , Issue.6937 , pp. 356-361
    • Firestein, G.S.1
  • 15
    • 77949571175 scopus 로고    scopus 로고
    • The risk of infections with biologic therapies for rheumatoid arthritis
    • 19117595 10.1016/j.semarthrit.2008.10.002 1:CAS:528:DC%2BC3cXjs1alt74%3D
    • D. E. Furst 2010 The risk of infections with biologic therapies for rheumatoid arthritis Semin. Arthritis Rheum. 39 327 346 19117595 10.1016/j.semarthrit.2008.10.002 1:CAS:528:DC%2BC3cXjs1alt74%3D
    • (2010) Semin. Arthritis Rheum. , vol.39 , pp. 327-346
    • Furst, D.E.1
  • 16
    • 33646378394 scopus 로고    scopus 로고
    • Targeting the inflamed synovium: The quest for specificity
    • DOI 10.1002/art.21720
    • T. Garrood C. Pitzalis 2006 Targeting the inflamed synovium: the quest for specificity Arthritis Rheum. 54 1055 1060 16575837 10.1002/art.21720 1:CAS:528:DC%2BD28XksVyht7w%3D (Pubitemid 43672917)
    • (2006) Arthritis and Rheumatism , vol.54 , Issue.4 , pp. 1055-1060
    • Garrood, T.1    Pitzalis, C.2
  • 17
    • 0035168461 scopus 로고    scopus 로고
    • Suppression of murine collagen-induced arthritis by targeted apoptosis of synovial neovasculature
    • DOI 10.1186/ar327
    • D. M. Gerlag E. Borges P. P. Tak H. M. Ellerby D. E. Bredesen R. Pasqualini E. Ruoslahti G. S. Firestein 2001 Suppression of murine collagen-induced arthritis by targeted apoptosis of synovial neovasculature Arthritis Res. 3 357 361 11714389 10.1186/ar327 1:CAS:528:DC%2BD38XjsVeltw%3D%3D (Pubitemid 33077115)
    • (2001) Arthritis Research , vol.3 , Issue.6 , pp. 357-361
    • Gerlag, D.M.1    Borges, E.2    Tak, P.P.3    Ellerby, H.M.4    Bredesen, D.E.5    Pasqualini, R.6    Ruoslahti, E.7    Firestein, G.S.8
  • 18
    • 23444444512 scopus 로고
    • Biodegradable long-circulating polymeric nanospheres
    • R. Gref Y. Minamitake M. T. Peracchia V. Trubetskoy V. Torchilin R. Langer 1994 Biodegradable long-circulating polymeric nanospheres Science 263 1600 1603 8128245 10.1126/science.8128245 1:CAS:528:DyaK2cXit1KktLc%3D (Pubitemid 24128361)
    • (1994) Science , vol.263 , Issue.5153 , pp. 1600-1603
    • Gref, R.1    Minamitake, Y.2    Peracchia, M.T.3    Trubetskoy, V.4    Torchilin, V.5    Langer, R.6
  • 19
    • 0028842728 scopus 로고
    • Engineering liposomes for drug delivery: Progress and problems
    • 8595139 10.1016/S0167-7799(00)89017-4 1:CAS:528:DyaK2MXpslansbk%3D
    • G. Gregoriadis 1995 Engineering liposomes for drug delivery: progress and problems Trends Biotechnol. 13 527 537 8595139 10.1016/S0167-7799(00)89017-4 1:CAS:528:DyaK2MXpslansbk%3D
    • (1995) Trends Biotechnol. , vol.13 , pp. 527-537
    • Gregoriadis, G.1
  • 20
    • 65249094231 scopus 로고    scopus 로고
    • Remission achieved after 2 years treatment with low-dose prednisolone in addition to disease-modifying anti-rheumatic drugs in early rheumatoid arthritis is associated with reduced joint destruction still present after 4 years: An open 2-year continuation study
    • 18420939 10.1136/ard.2008.087833 1:STN:280:DC%2BD1M3gsFygtg%3D%3D
    • I. Hafstrom K. Albertsson A. Boonen D. Van Der Heijde R. Landewe B. Svensson 2009 Remission achieved after 2 years treatment with low-dose prednisolone in addition to disease-modifying anti-rheumatic drugs in early rheumatoid arthritis is associated with reduced joint destruction still present after 4 years: an open 2-year continuation study Ann. Rheum. Dis. 68 508 513 18420939 10.1136/ard.2008.087833 1:STN:280:DC%2BD1M3gsFygtg%3D%3D
    • (2009) Ann. Rheum. Dis. , vol.68 , pp. 508-513
    • Hafstrom, I.1    Albertsson, K.2    Boonen, A.3    Van Der Heijde, D.4    Landewe, R.5    Svensson, B.6
  • 21
    • 33745700031 scopus 로고    scopus 로고
    • Folate-linked lipid-based nanoparticles deliver a NFkappaB decoy into activated murine macrophage-like RAW264.7 cells
    • 16819203 10.1248/bpb.29.1516 1:CAS:528:DC%2BD28XovFKqtLk%3D
    • Y. Hattori M. Sakaguchi Y. Maitani 2006 Folate-linked lipid-based nanoparticles deliver a NFkappaB decoy into activated murine macrophage-like RAW264.7 cells Biol. Pharm. Bull. 29 1516 1520 16819203 10.1248/bpb.29.1516 1:CAS:528:DC%2BD28XovFKqtLk%3D
    • (2006) Biol. Pharm. Bull. , vol.29 , pp. 1516-1520
    • Hattori, Y.1    Sakaguchi, M.2    Maitani, Y.3
  • 22
    • 0001294268 scopus 로고
    • Comparative effects of use of hydrocortisone as a local antiarthritic agent
    • 10.1001/jama.1951.03670340019005 1:STN:280:DyaG38%2FhtVGhtw%3D%3D
    • J. Hollander E. Brown R. Jessar C. Brown 1951 Comparative effects of use of hydrocortisone as a local antiarthritic agent JAMA 147 1629 1635 10.1001/jama.1951.03670340019005 1:STN:280:DyaG38%2FhtVGhtw%3D%3D
    • (1951) JAMA , vol.147 , pp. 1629-1635
    • Hollander, J.1    Brown, E.2    Jessar, R.3    Brown, C.4
  • 23
    • 0037189380 scopus 로고    scopus 로고
    • Tumor regression by targeted gene delivery to the neovasculature
    • DOI 10.1126/science.1070200
    • J. D. Hood M. Bednarski R. Frausto S. Guccione R. A. Reisfeld R. Xiang D. A. Cheresh 2002 Tumor regression by targeted gene delivery to the neovasculature Science 296 2404 2407 12089446 10.1126/science.1070200 1:CAS:528:DC%2BD38XltFWksrk%3D (Pubitemid 34734217)
    • (2002) Science , vol.296 , Issue.5577 , pp. 2404-2407
    • Hood, J.D.1    Bednarski, M.2    Frausto, R.3    Guccione, S.4    Reisfeld, R.A.5    Xiang, R.6    Cheresh, D.A.7
  • 24
    • 0036108432 scopus 로고    scopus 로고
    • Prolonged anti-inflammatory action of DL-lactide/glycolide copolymer nanospheres containing betamethasone sodium phosphate for an intra-articular delivery system in antigen-induced arthritic rabbit
    • DOI 10.1023/A:1015123024113
    • E. Horisawa T. Hirota S. Kawazoe J. Yamada H. Yamamoto H. Takeuchi Y. Kawashima 2002 Prolonged antiinflammatory action of DL-lactide/glycolide copolymer nanospheres containing betamethasone sodium phosphate for an intra-articular delivery system in antigen-induced arthritic rabbit Pharm. Res. 19 403 410 12033371 10.1023/A:1015123024113 1:CAS:528:DC%2BD38XjvFejsr0%3D (Pubitemid 34408936)
    • (2002) Pharmaceutical Research , vol.19 , Issue.4 , pp. 403-410
    • Horisawa, E.1    Hirota, T.2    Kawazoe, S.3    Yamada, J.4    Yamamoto, H.5    Takeuchi, H.6    Kawashima, Y.7
  • 25
    • 0036182057 scopus 로고    scopus 로고
    • Size-dependency of DL-lactide/glycolide copolymer particulates for intra-articular delivery system on phagocytosis in rat synovium
    • DOI 10.1023/A:1014260513728
    • E. Horisawa K. Kubota I. Tuboi K. Sato H. Yamamoto H. Takeuchi Y. Kawashima 2002 Size-dependency of DLlactide/glycolide copolymer particulates for intra-articular delivery system on phagocytosis in rat synovium Pharm. Res. 19 132 139 11883639 10.1023/A:1014260513728 1:CAS:528:DC%2BD38XitVSmu7g%3D (Pubitemid 34165397)
    • (2002) Pharmaceutical Research , vol.19 , Issue.2 , pp. 132-139
    • Horisawa, E.1    Kubota, K.2    Tuboi, I.3    Sato, K.4    Yamamoto, H.5    Takeuchi, H.6    Kawashima, Y.7
  • 26
    • 65649115761 scopus 로고    scopus 로고
    • Treatment of experimental arthritis with stealth-type polymeric nanoparticles encapsulating betamethasone phosphate
    • 19244548 10.1124/jpet.108.150276 1:CAS:528:DC%2BD1MXlt1Omurs%3D
    • T. Ishihara T. Kubota T. Choi M. Higaki 2009 Treatment of experimental arthritis with stealth-type polymeric nanoparticles encapsulating betamethasone phosphate J. Pharmacol. Exp. Ther. 329 412 417 19244548 10.1124/jpet.108.150276 1:CAS:528:DC%2BD1MXlt1Omurs%3D
    • (2009) J. Pharmacol. Exp. Ther. , vol.329 , pp. 412-417
    • Ishihara, T.1    Kubota, T.2    Choi, T.3    Higaki, M.4
  • 27
    • 0030611047 scopus 로고    scopus 로고
    • A comparison between 111In-anti-Eselectin mAb and 99Tcm-labelled human non-specific immunoglobulin in radionuclide imaging of rheumatoid arthritis
    • 9227228 1:STN:280:DyaK2szntFSjsQ%3D%3D
    • F. Jamar P. Chapman D. Manicourt D. Glass D. Haskard A. Peters 1997 A comparison between 111In-anti-Eselectin mAb and 99Tcm-labelled human non-specific immunoglobulin in radionuclide imaging of rheumatoid arthritis Br. J. Radiol. 70 473 9227228 1:STN:280:DyaK2szntFSjsQ%3D%3D
    • (1997) Br. J. Radiol. , vol.70 , pp. 473
    • Jamar, F.1    Chapman, P.2    Manicourt, D.3    Glass, D.4    Haskard, D.5    Peters, A.6
  • 28
    • 33745014998 scopus 로고    scopus 로고
    • Efficient new cationic liposome formulation for systemic delivery of small interfering RNA silencing tumor necrosis factor α in experimental arthritis
    • DOI 10.1002/art.21876
    • M. Khoury P. Louis-Plence V. Escriou D. Noel C. Largeau C. Cantos D. Scherman C. Jorgensen F. Apparailly 2006 Efficient new cationic liposome formulation for systemic delivery of small interfering RNA silencing tumor necrosis factor alpha in experimental arthritis Arthritis Rheum. 54 1867 1877 16729293 10.1002/art.21876 1:CAS:528:DC%2BD28Xms1Sju70%3D (Pubitemid 43877936)
    • (2006) Arthritis and Rheumatism , vol.54 , Issue.6 , pp. 1867-1877
    • Khoury, M.1    Louis-Plence, P.2    Escriou, V.3    Noel, D.4    Largeau, C.5    Cantos, C.6    Scherman, D.7    Jorgensen, C.8    Apparailly, F.9
  • 29
    • 0142187335 scopus 로고    scopus 로고
    • Angiogenesis as a target in rheumatoid arthritis
    • Koch, A., Angiogenesis as a target in rheumatoid arthritis. Ann. Rheum. Dis., 62, ii60-ii67 (2003).
    • (2003) Ann. Rheum. Dis. , vol.62
    • Koch, A.1
  • 30
    • 33646381864 scopus 로고    scopus 로고
    • Targeting of angiogenic endothelial cells at sites of inflammation by dexamethasone phosphate-containing RGD peptide liposomes inhibits experimental arthritis
    • DOI 10.1002/art.21719
    • G. A. Koning R. M. Schiffelers M. H. Wauben R. J. Kok E. Mastrobattista G. Molema T. L. Ten Hagen G. Storm 2006 Targeting of angiogenic endothelial cells at sites of inflammation by dexamethasone phosphate-containing RGD peptide liposomes inhibits experimental arthritis Arthritis Rheum. 54 1198 1208 16575845 10.1002/art.21719 1:CAS:528:DC%2BD28XksVyhtLg%3D (Pubitemid 43672932)
    • (2006) Arthritis and Rheumatism , vol.54 , Issue.4 , pp. 1198-1208
    • Koning, G.A.1    Schiffelers, R.M.2    Wauben, M.H.M.3    Kok, R.J.4    Mastrobattista, E.5    Molema, G.6    Ten Hagen, T.L.M.7    Storm, G.8
  • 32
    • 0025367285 scopus 로고
    • Hypoxia and acidosis in chronic inflammatory arthritis; Relation to vascular supply and dynamic effusion pressure
    • J. R. Levick 1990 Hypoxia and acidosis in chronic inflammatory arthritis; relation to vascular supply and dynamic effusion pressure J. Rheumatol. 17 579 582 2359066 1:STN:280:DyaK3c3psVaisA%3D%3D (Pubitemid 20201730)
    • (1990) Journal of Rheumatology , vol.17 , Issue.5 , pp. 579-582
    • Levick, J.R.1
  • 33
    • 1842429963 scopus 로고    scopus 로고
    • Methotrexate Loaded Poly(L-Lactic Acid) Microspheres for Intra-Articular Delivery of Methotrexate to the Joint
    • DOI 10.1002/jps.20031
    • L. S. Liang J. Jackson W. Min V. Risovic K. M. Wasan H. M. Burt 2004 Methotrexate loaded poly(L-lactic acid) microspheres for intra-articular delivery of methotrexate to the joint J. Pharm. Sci. 93 943 956 14999731 10.1002/jps.20031 1:CAS:528:DC%2BD2cXivF2ltr4%3D (Pubitemid 38420405)
    • (2004) Journal of Pharmaceutical Sciences , vol.93 , Issue.4 , pp. 943-956
    • Liang, L.S.1    Jackson, J.2    Min, W.3    Risovic, V.4    Wasan, K.M.5    Burt, H.M.6
  • 34
    • 21344449508 scopus 로고    scopus 로고
    • Pharmacokinetic study of methotrexate following intra-articular injection of methotrexate loaded poly(L-lactic acid) microspheres in rabbits
    • DOI 10.1002/jps.20341
    • L. S. Liang W. Wong H. M. Burt 2005 Pharmacokinetic study of methotrexate following intra-articular injection of methotrexate loaded poly(L-lactic acid) microspheres in rabbits J. Pharm. Sci. 94 1204 1215 15858840 10.1002/jps.20341 1:CAS:528:DC%2BD2MXkvF2qtL4%3D (Pubitemid 40904185)
    • (2005) Journal of Pharmaceutical Sciences , vol.94 , Issue.6 , pp. 1204-1215
    • Liang, L.S.1    Wong, W.2    Burt, H.M.3
  • 35
    • 4344579795 scopus 로고    scopus 로고
    • Intra-articular treatment of arthritis with microsphere formulations of paclitaxel: Biocompatibility and efficacy determinations in rabbits
    • R. T. Liggins T. Cruz W. Min L. Liang W. L. Hunter H. M. Burt 2004 Intra-articular treatment of arthritis with microsphere formulations of paclitaxel: biocompatibility and efficacy determinations in rabbits Inflamm. Res. 53 363 372 15316667 10.1007/s00011-004-1273-1 1:CAS:528: DC%2BD2cXns1ejs7c%3D (Pubitemid 39141750)
    • (2004) Inflammation Research , vol.53 , Issue.8 , pp. 363-372
    • Liggins, R.T.1    Cruz, T.2    Min, W.3    Liang, L.4    Hunter, W.L.5    Burt, H.M.6
  • 37
    • 28744456012 scopus 로고    scopus 로고
    • Characterization of folate-chitosan-DNA nanoparticles for gene therapy
    • DOI 10.1016/j.biomaterials.2005.09.020, PII S0142961205008628
    • S. Mansouri Y. Cuie F. Winnik Q. Shi P. Lavigne M. Benderdour E. Beaumont J. C. Fernandes 2006 Characterization of folate-chitosan-DNA nanoparticles for gene therapy Biomaterials 27 2060 2065 16202449 10.1016/j.biomaterials.2005.09. 020 1:CAS:528:DC%2BD2MXht12isb7J (Pubitemid 41759500)
    • (2006) Biomaterials , vol.27 , Issue.9 , pp. 2060-2065
    • Mansouri, S.1    Cuie, Y.2    Winnik, F.3    Shi, Q.4    Lavigne, P.5    Benderdour, M.6    Beaumont, E.7    Fernandes, J.C.8
  • 38
    • 0035937129 scopus 로고    scopus 로고
    • Prevalence of disabilities and associated health conditions among adults-United States, 1999
    • J. Mcneil J. Binette 2001 Prevalence of disabilities and associated health conditions among adults-United States, 1999 MMWR Morb. Mortal. Wkly. Rep. 50 120 125
    • (2001) MMWR Morb. Mortal. Wkly. Rep. , vol.50 , pp. 120-125
    • McNeil, J.1    Binette, J.2
  • 39
    • 0038002438 scopus 로고    scopus 로고
    • Complete remission of experimental arthritis by joint targeting of glucocorticoids with long-circulating liposomes
    • DOI 10.1002/art.11140
    • J. M. Metselaar M. H. Wauben J. P. Wagenaar-Hilbers O. C. Boerman G. Storm 2003 Complete remission of experimental arthritis by joint targeting of glucocorticoids with long-circulating liposomes Arthritis Rheum. 48 2059 2066 12847701 10.1002/art.11140 1:CAS:528:DC%2BD3sXmtFarur4%3D (Pubitemid 36828702)
    • (2003) Arthritis and Rheumatism , vol.48 , Issue.7 , pp. 2059-2066
    • Metselaar, J.M.1    Wauben, M.H.M.2    Wagenaar-Hilbers, J.P.A.3    Boerman, O.C.4    Storm, G.5
  • 40
    • 1842505688 scopus 로고    scopus 로고
    • Liposomal targeting of glucocorticoids to synovial lining cells strongly increases therapeutic benefit in collagen type II arthritis
    • DOI 10.1136/ard.2003.009944
    • J. M. Metselaar W. B. Van Den Berg A. E. Holthuysen M. H. Wauben G. Storm P. L. Van Lent 2004 Liposomal targeting of glucocorticoids to synovial lining cells strongly increases therapeutic benefit in collagen type II arthritis Ann. Rheum. Dis. 63 348 353 15020326 10.1136/ard.2003.009944 1:CAS:528: DC%2BD2cXjs1ahsrk%3D (Pubitemid 38453298)
    • (2004) Annals of the Rheumatic Diseases , vol.63 , Issue.4 , pp. 348-353
    • Metselaar, J.M.1    Van Den Berg, W.B.2    Holthuysen, A.E.M.3    Wauben, M.H.M.4    Storm, G.5    Van Lent, P.L.E.M.6
  • 41
    • 34248524004 scopus 로고    scopus 로고
    • The antiinflammatory mechanism of methotrexate depends on extracellular conversion of adenine nucleotides to adenosine by ecto-5′-nucleotidase: Findings in a study of ecto-5′-nucleotidase gene-deficient mice
    • DOI 10.1002/art.22643
    • M. C. Montesinos M. Takedachi L. F. Thompson T. F. Wilder P. Fernandez B. N. Cronstein 2007 The antiinflammatory mechanism of methotrexate depends on extracellular conversion of adenine nucleotides to adenosine by ecto-5'-nucleotidase: findings in a study of ecto-5'-nucleotidase gene-deficient mice Arthritis Rheum. 56 1440 1445 17469101 10.1002/art.22643 1:CAS:528:DC%2BD2sXmsFart7s%3D (Pubitemid 46764071)
    • (2007) Arthritis and Rheumatism , vol.56 , Issue.5 , pp. 1440-1445
    • Montesinos, M.C.1    Takedachi, M.2    Thompson, L.F.3    Wilder, T.F.4    Fernandez, P.5    Cronstein, B.N.6
  • 42
    • 0038032150 scopus 로고    scopus 로고
    • Solid lipid nanoparticles (SLN) for controlled drug delivery - A review of the state of the art
    • DOI 10.1016/S0939-6411(00)00087-4, PII S0939641100000874
    • R. H. Muller K. Mader S. Gohla 2000 Solid lipid nanoparticles (SLN) for controlled drug delivery - a review of the state of the art Eur. J. Pharm. Biopharm. 50 161 177 10840199 10.1016/S0939-6411(00)00087-4 1:CAS:528: DC%2BD3cXjslyisrg%3D (Pubitemid 30326695)
    • (2000) European Journal of Pharmaceutics and Biopharmaceutics , vol.50 , Issue.1 , pp. 161-177
    • Muller, R.H.1    Mader, K.2    Gohla, S.3
  • 43
    • 0038639722 scopus 로고    scopus 로고
    • CD44 in rheumatoid arthritis
    • 12723975 10.1186/ar746 1:CAS:528:DC%2BD3sXjtlens7Y%3D
    • D. Naor S. Nedvetzki 2003 CD44 in rheumatoid arthritis Arthritis Res. Ther. 5 105 115 12723975 10.1186/ar746 1:CAS:528:DC%2BD3sXjtlens7Y%3D
    • (2003) Arthritis Res. Ther. , vol.5 , pp. 105-115
    • Naor, D.1    Nedvetzki, S.2
  • 44
    • 78650042455 scopus 로고    scopus 로고
    • Formulation and evaluation of quercetin polycaprolactone microspheres for the treatment of rheumatoid arthritis
    • 20607810 10.1002/jps.22266 1:CAS:528:DC%2BC3cXhsFegtr7I
    • V. Natarajan N. Krithica B. Madhan P. K. Sehgal 2011 Formulation and evaluation of quercetin polycaprolactone microspheres for the treatment of rheumatoid arthritis J. Pharm. Sci. 100 195 205 20607810 10.1002/jps.22266 1:CAS:528:DC%2BC3cXhsFegtr7I
    • (2011) J. Pharm. Sci. , vol.100 , pp. 195-205
    • Natarajan, V.1    Krithica, N.2    Madhan, B.3    Sehgal, P.K.4
  • 46
    • 28844488494 scopus 로고    scopus 로고
    • Opsonization, biodistribution, and pharmacokinetics of polymeric nanoparticles
    • DOI 10.1016/j.ijpharm.2005.10.010, PII S037851730500668X
    • D. E. 3. Owens N. A. Peppas 2006 Opsonization, biodistribution, and pharmacokinetics of polymeric nanoparticles Int. J. Pharm. 307 93 102 16303268 10.1016/j.ijpharm.2005.10.010 1:CAS:528:DC%2BD2MXht12isrvM (Pubitemid 41773257)
    • (2006) International Journal of Pharmaceutics , vol.307 , Issue.1 , pp. 93-102
    • Owens III, D.E.1    Peppas, N.A.2
  • 47
    • 1942503257 scopus 로고    scopus 로고
    • Folate receptor-mediated targeting of therapeutic and imaging agents to activated macrophages in rheumatoid arthritis
    • DOI 10.1016/j.addr.2004.01.012, PII S0169409X04000225
    • C. M. Paulos M. J. Turk G. J. Breur P. S. Low 2004 Folate receptor-mediated targeting of therapeutic and imaging agents to activated macrophages in rheumatoid arthritis Adv. Drug Deliv. Rev. 56 1205 1217 15094216 10.1016/j.addr.2004.01.012 1:CAS:528:DC%2BD2cXjtF2rtLk%3D (Pubitemid 38496516)
    • (2004) Advanced Drug Delivery Reviews , vol.56 , Issue.8 , pp. 1205-1217
    • Paulos, C.M.1    Turk, M.J.2    Breur, G.J.3    Low, P.S.4
  • 48
    • 34547109974 scopus 로고    scopus 로고
    • Folate-targeted immunotherapy effectively treats established adjuvant and collagen-induced arthritis
    • 16646988 10.1186/ar1944
    • C. M. Paulos B. Varghese W. R. Widmer G. J. Breur E. Vlashi P. S. Low 2006 Folate-targeted immunotherapy effectively treats established adjuvant and collagen-induced arthritis Arthritis Res. Ther. 8 R77 16646988 10.1186/ar1944
    • (2006) Arthritis Res. Ther. , vol.8 , pp. 77
    • Paulos, C.M.1    Varghese, B.2    Widmer, W.R.3    Breur, G.J.4    Vlashi, E.5    Low, P.S.6
  • 49
    • 0027077654 scopus 로고
    • Longterm drug therapy for rheumatoid arthritis in seven rheumatology private practices: II. Second line drugs and prednisone
    • T. Pincus S. B. Marcum L. F. Callahan 1992 Longterm drug therapy for rheumatoid arthritis in seven rheumatology private practices: II. Second line drugs and prednisone J. Rheumatol. 19 1885 1894 1294735 1:STN:280: DyaK3s7psFyktg%3D%3D (Pubitemid 23018519)
    • (1992) Journal of Rheumatology , vol.19 , Issue.12 , pp. 1885-1894
    • Pincus, T.1    Marcum, S.B.2    Callahan, L.F.3
  • 50
    • 79959858929 scopus 로고    scopus 로고
    • Imaging of activated macrophages in experimental osteoarthritis using folate targeted animal singlephoton-emission computed tomography/computed tomography
    • 21437875 10.1002/art.30363
    • T. M. Piscaer C. Müller T. L. Mindt E. Lubberts J. A. Verhaar E. P. Krenning R. Schibli M. De Jong H. Weinans 2011 Imaging of activated macrophages in experimental osteoarthritis using folate targeted animal singlephoton- emission computed tomography/computed tomography Arthritis Rheum. 63 1898 1907 21437875 10.1002/art.30363
    • (2011) Arthritis Rheum. , vol.63 , pp. 1898-1907
    • Piscaer, T.M.1    Müller, C.2    Mindt, T.L.3    Lubberts, E.4    Verhaar, J.A.5    Krenning, E.P.6    Schibli, R.7    De Jong, M.8    Weinans, H.9
  • 51
    • 0023127212 scopus 로고
    • Albumin microspheres for intra-articular drug delivery: Investigation of their retention in normal and arthritic knee joints of rabbits
    • J. H. Ratcliffe I. M. Hunneyball C. G. Wilson A. Smith S. S. Davis 1987 Albumin microspheres for intra-articular drug delivery: investigation of their retention in normal and arthritic knee joints of rabbits J. Pharm. Pharmacol. 39 290 295 2884293 10.1111/j.2042-7158.1987.tb06268.x 1:CAS:528:DyaL2sXhvVamtbo%3D (Pubitemid 17046856)
    • (1987) Journal of Pharmacy and Pharmacology , vol.39 , Issue.4 , pp. 290-295
    • Ratcliffe, J.H.1    Hunneyball, I.M.2    Wilson, C.G.3
  • 52
    • 25844463660 scopus 로고    scopus 로고
    • Biphasic Janus particles with nanoscale anisotropy
    • DOI 10.1038/nmat1486
    • K. H. Roh D. C. Martin J. Lahann 2005 Biphasic Janus particles with nanoscale anisotropy Nat. Mater. 4 759 763 16184172 10.1038/nmat1486 1:CAS:528:DC%2BD2MXhtVGgu77F (Pubitemid 41397023)
    • (2005) Nature Materials , vol.4 , Issue.10 , pp. 759-763
    • Roh, K.-H.1    Martin, D.C.2    Lahann, J.3
  • 53
    • 38049165716 scopus 로고    scopus 로고
    • Sheddable coatings for long-circulating nanoparticles
    • 17551809 10.1007/s11095-007-9348-7 1:CAS:528:DC%2BD1cXkslSnsg%3D%3D
    • B. Romberg W. E. Hennink G. Storm 2008 Sheddable coatings for long-circulating nanoparticles Pharm. Res. 25 55 71 17551809 10.1007/s11095-007-9348-7 1:CAS:528:DC%2BD1cXkslSnsg%3D%3D
    • (2008) Pharm. Res. , vol.25 , pp. 55-71
    • Romberg, B.1    Hennink, W.E.2    Storm, G.3
  • 54
    • 0036618459 scopus 로고    scopus 로고
    • Glucocorticoid use in rheumatoid arthritis
    • 12010606 10.1007/s11926-002-0068-z
    • K. G. Saag 2002 Glucocorticoid use in rheumatoid arthritis Curr. Rheumatol. Rep. 4 218 225 12010606 10.1007/s11926-002-0068-z
    • (2002) Curr. Rheumatol. Rep. , vol.4 , pp. 218-225
    • Saag, K.G.1
  • 56
    • 77952670612 scopus 로고    scopus 로고
    • Chitosan-based nanogels for selective delivery of photosensitizers to macrophages and improved retention in and therapy of articular joints
    • 20152870 10.1016/j.jconrel.2010.02.008 1:CAS:528:DC%2BC3cXlslCrur4%3D
    • F. Schmitt L. Lagopoulos P. Kauper N. Rossi N. Busso J. Barge G. Wagnieres C. Laue C. Wandrey L. Juillerat-Jeanneret 2010 Chitosan-based nanogels for selective delivery of photosensitizers to macrophages and improved retention in and therapy of articular joints J. Control. Release 144 242 250 20152870 10.1016/j.jconrel.2010.02.008 1:CAS:528:DC%2BC3cXlslCrur4%3D
    • (2010) J. Control. Release , vol.144 , pp. 242-250
    • Schmitt, F.1    Lagopoulos, L.2    Kauper, P.3    Rossi, N.4    Busso, N.5    Barge, J.6    Wagnieres, G.7    Laue, C.8    Wandrey, C.9    Juillerat-Jeanneret, L.10
  • 57
    • 70350531479 scopus 로고    scopus 로고
    • Prospective new biological therapies for rheumatoid arthritis
    • 19328245 10.1016/j.autrev.2009.03.010 1:CAS:528:DC%2BD1MXhs1SjtL7M
    • L. Senolt J. Vencovsky K. Pavelka C. Ospelt S. Gay 2009 Prospective new biological therapies for rheumatoid arthritis Autoimmun. Rev. 9 102 107 19328245 10.1016/j.autrev.2009.03.010 1:CAS:528:DC%2BD1MXhs1SjtL7M
    • (2009) Autoimmun. Rev. , vol.9 , pp. 102-107
    • Senolt, L.1    Vencovsky, J.2    Pavelka, K.3    Ospelt, C.4    Gay, S.5
  • 58
    • 78049465753 scopus 로고    scopus 로고
    • Polymer particle shape independently influences binding and internalization by macrophages
    • 20691741 10.1016/j.jconrel.2010.07.116 1:CAS:528:DC%2BC3cXhtlygt7nO
    • G. Sharma D. T. Valenta Y. Altman S. Harvey H. Xie S. Mitragotri J. W. Smith 2010 Polymer particle shape independently influences binding and internalization by macrophages J. Control. Release 147 408 412 20691741 10.1016/j.jconrel.2010.07.116 1:CAS:528:DC%2BC3cXhtlygt7nO
    • (2010) J. Control. Release , vol.147 , pp. 408-412
    • Sharma, G.1    Valenta, D.T.2    Altman, Y.3    Harvey, S.4    Xie, H.5    Mitragotri, S.6    Smith, J.W.7
  • 59
    • 44749084983 scopus 로고    scopus 로고
    • Prolongation of residence time of liposome by surface-modification with mixture of hydrophilic polymers
    • 18486370 10.1016/j.ijpharm.2008.04.004 1:CAS:528:DC%2BD1cXmvVems7w%3D
    • T. Shehata K. Ogawara K. Higaki T. Kimura 2008 Prolongation of residence time of liposome by surface-modification with mixture of hydrophilic polymers Int. J. Pharm. 359 272 279 18486370 10.1016/j.ijpharm.2008.04.004 1:CAS:528:DC%2BD1cXmvVems7w%3D
    • (2008) Int. J. Pharm. , vol.359 , pp. 272-279
    • Shehata, T.1    Ogawara, K.2    Higaki, K.3    Kimura, T.4
  • 60
    • 79952218561 scopus 로고    scopus 로고
    • Hydrodynamic delivery of chitosan-folate-DNA nanoparticles in rats with adjuvant-induced arthritis
    • 21274258 10.1155/2011/148763
    • Q. Shi H. Wang C. Tran X. Qiu F. M. Winnik X. Zhang K. Dai M. Benderdour J. C. Fernandes 2011 Hydrodynamic delivery of chitosan-folate-DNA nanoparticles in rats with adjuvant-induced arthritis J. Biomed. Biotechnol. 2011 148763 21274258 10.1155/2011/148763
    • (2011) J. Biomed. Biotechnol. , vol.2011 , pp. 148763
    • Shi, Q.1    Wang, H.2    Tran, C.3    Qiu, X.4    Winnik, F.M.5    Zhang, X.6    Dai, K.7    Benderdour, M.8    Fernandes, J.C.9
  • 61
    • 0343247711 scopus 로고    scopus 로고
    • Biodegradation and biocompatibility of PLA and PLGA microspheres
    • DOI 10.1016/S0169-409X(97)00048-3, PII S0169409X97000483
    • M. S. Shive J. M. Anderson 1997 Biodegradation and biocompatibility of PLA and PLGA microspheres Adv. Drug Deliv. Rev. 28 5 24 10837562 10.1016/S0169-409X(97)00048-3 (Pubitemid 27497671)
    • (1997) Advanced Drug Delivery Reviews , vol.28 , Issue.1 , pp. 5-24
    • Anderson, J.M.1    Shive, M.S.2
  • 62
    • 0034068820 scopus 로고    scopus 로고
    • DMARDs in the treatment of rheumatoid arthritis: Current agents and future developments
    • L. S. Simon 2000 DMARDs in the treatment of rheumatoid arthritis: current agents and future developments Int. J. Clin. Pract. 54 243 249 10912314 1:CAS:528:DC%2BD3cXktFGis7g%3D (Pubitemid 30319211)
    • (2000) International Journal of Clinical Practice , vol.54 , Issue.4 , pp. 243-249
    • Simon, L.S.1
  • 63
    • 0038131975 scopus 로고    scopus 로고
    • Therapeutic strategies for rheumatoid arthritis
    • DOI 10.1038/nrd1109
    • J. S. Smolen G. Steiner 2003 Therapeutic strategies for rheumatoid arthritis Nat. Rev. Drug Discov. 2 473 488 12776222 10.1038/nrd1109 1:CAS:528:DC%2BD3sXktFOhu7o%3D (Pubitemid 37361728)
    • (2003) Nature Reviews Drug Discovery , vol.2 , Issue.6 , pp. 473-488
    • Smolen, J.S.1    Steiner, G.2
  • 64
    • 0036898723 scopus 로고    scopus 로고
    • Management of glucocorticoid-induced osteoporosis in patients with rheumatoid arthritis: Rates and predictors of care in an academic rheumatology practice
    • DOI 10.1002/art.10613
    • D. H. Solomon J. N. Katz J. P. Jacobs A. M. La Tourette J. Coblyn 2002 Management of glucocorticoid induced osteoporosis in patients with rheumatoid arthritis: Rates and predictors of care in an academic rheumatology practice Arthritis Rheum. 46 3136 3142 12483716 10.1002/art.10613 (Pubitemid 35453521)
    • (2002) Arthritis and Rheumatism , vol.46 , Issue.12 , pp. 3136-3142
    • Solomon, D.H.1    Katz, J.N.2    Jacobs, J.P.3    La Tourette, A.M.4    Coblyn, J.5
  • 65
    • 33845882484 scopus 로고    scopus 로고
    • Biologic therapies in rheumatology: Lessons learned, future directions
    • DOI 10.1038/nrd2196, PII NRD2196
    • V. Strand R. Kimberly J. D. Isaacs 2007 Biologic therapies in rheumatology: lessons learned, future directions Nat. Rev. Drug Discov. 6 75 92 17195034 10.1038/nrd2196 1:CAS:528:DC%2BD28XhtlGktbbE (Pubitemid 46020288)
    • (2007) Nature Reviews Drug Discovery , vol.6 , Issue.1 , pp. 75-92
    • Strand, V.1    Kimberly, R.2    Isaacs, J.D.3
  • 66
    • 27744466694 scopus 로고    scopus 로고
    • Low-dose prednisolone in addition to the initial disease-modifying antirheumatic drug in patients with early active rheumatoid arthritis reduces joint destruction and increases the remission rate: A two-year randomized trial
    • DOI 10.1002/art.21298
    • B. Svensson A. Boonen K. Albertsson D. Van Der Heijde C. Keller I. Hafstrom 2005 Low-dose prednisolone in addition to the initial disease-modifying antirheumatic drug in patients with early active rheumatoid arthritis reduces joint destruction and increases the remission rate: a twoyear randomized trial Arthritis Rheum. 52 3360 3370 16255010 10.1002/art.21298 1:CAS:528: DC%2BD2MXht1KrtbfJ (Pubitemid 41612202)
    • (2005) Arthritis and Rheumatism , vol.52 , Issue.11 , pp. 3360-3370
    • Svensson, B.1    Boonen, A.2    Albertsson, K.3    Van Der Heijde, D.4    Keller, C.5    Hafstrom, I.6
  • 67
    • 10844240687 scopus 로고    scopus 로고
    • The different stages of synovitis: Acute vs chronic, early vs late and non-erosive vs erosive
    • DOI 10.1016/j.berh.2004.08.002, PII S1521694204001202, Early Rheumatoid Arthritis
    • I. H. Tarner P. Harle U. Muller-Ladner R. E. Gay S. Gay 2005 The different stages of synovitis: acute vs chronic, early vs late and non-erosive vs erosive Best Pract. Res. Clin. Rheumatol. 19 19 35 15588969 10.1016/j.berh.2004.08.002 (Pubitemid 40003939)
    • (2005) Best Practice and Research: Clinical Rheumatology , vol.19 , Issue.1 , pp. 19-35
    • Tarner, I.H.1    Harle, P.2    Muller-Ladner, U.3    Gay, R.E.4    Gay, S.5
  • 68
    • 54049149432 scopus 로고    scopus 로고
    • Drug delivery systems for the treatment of rheumatoid arthritis
    • 18754751 10.1517/17425247.5.9.1027 1:CAS:528:DC%2BD1cXhtVGktrnN
    • I. H. Tarner U. Muller-Ladner 2008 Drug delivery systems for the treatment of rheumatoid arthritis Expert Opin. Drug Deliv. 5 1027 1037 18754751 10.1517/17425247.5.9.1027 1:CAS:528:DC%2BD1cXhtVGktrnN
    • (2008) Expert Opin. Drug Deliv. , vol.5 , pp. 1027-1037
    • Tarner, I.H.1    Muller-Ladner, U.2
  • 69
    • 0033506335 scopus 로고    scopus 로고
    • Suppressed severity of collagen-induced arthritis by in vivo transfection of nuclear factor κB decoy oligodeoxynucleotides as a gene therapy
    • DOI 10.1002/1529-0131(199912)42:12<2532::AID-ANR5>3.0.CO;2-2
    • T. Tomita E. Takeuchi N. Tomita R. Morishita M. Kaneko K. Yamamoto T. Nakase H. Seki K. Kato Y. Kaneda T. Ochi 1999 Suppressed severity of collagen-induced arthritis by in vivo transfection of nuclear factor kappaB decoy oligodeoxynucleotides as a gene therapy Arthritis Rheum. 42 2532 2542 10615998 10.1002/1529-0131(199912)42:12<2532::AID-ANR5>3.0.CO;2-2 1:CAS:528:DC%2BD3cXjslagtA%3D%3D (Pubitemid 30327169)
    • (1999) Arthritis and Rheumatism , vol.42 , Issue.12 , pp. 2532-2542
    • Tomita, T.1    Takeuchi, E.2    Tomita, N.3    Morishita, R.4    Kaneko, M.5    Yamamoto, K.6    Nakase, T.7    Seki, H.8    Kato, K.9    Kaneda, Y.10    Ochi, T.11
  • 70
    • 79953048071 scopus 로고    scopus 로고
    • Tumor delivery of macromolecular drugs based on the EPR effect
    • 20304019 10.1016/j.addr.2010.03.011 1:CAS:528:DC%2BC3MXktF2jur4%3D
    • V. Torchilin 2011 Tumor delivery of macromolecular drugs based on the EPR effect Adv. Drug Deliv. Rev. 63 131 135 20304019 10.1016/j.addr.2010.03.011 1:CAS:528:DC%2BC3MXktF2jur4%3D
    • (2011) Adv. Drug Deliv. Rev. , vol.63 , pp. 131-135
    • Torchilin, V.1
  • 71
    • 0036068396 scopus 로고    scopus 로고
    • Folate-targeted imaging of activated macrophages in rats with adjuvant-induced arthritis
    • DOI 10.1002/art.10405
    • M. J. Turk G. J. Breur W. R. Widmer C. M. Paulos L. C. Xu L. A. Grote P. S. Low 2002 Folate-targeted imaging of activated macrophages in rats with adjuvant-induced arthritis Arthritis Rheum. 46 1947 1955 12124880 10.1002/art.10405 (Pubitemid 34774528)
    • (2002) Arthritis and Rheumatism , vol.46 , Issue.7 , pp. 1947-1955
    • Turk, M.J.1    Breur, G.J.2    Widmer, W.R.3    Paulos, C.M.4    Xu, L.-C.5    Grote, L.A.6    Low, P.S.7
  • 72
    • 17644415370 scopus 로고    scopus 로고
    • Monodisperse double emulsions generated from a microcapillary device
    • DOI 10.1126/science.1109164
    • A. S. Utada E. Lorenceau D. R. Link P. D. Kaplan H. A. Stone D. A. Weitz 2005 Monodisperse double emulsions generated from a microcapillary device Science 308 537 541 15845850 10.1126/science.1109164 1:CAS:528: DC%2BD2MXjtlOjtrk%3D (Pubitemid 40570581)
    • (2005) Science , vol.308 , Issue.5721 , pp. 537-541
    • Utada, A.S.1    Lorenceau, E.2    Link, D.R.3    Kaplan, P.D.4    Stone, H.A.5    Weitz, D.A.6
  • 74
    • 70349961778 scopus 로고    scopus 로고
    • Treatment of rheumatoid arthritis: State of the art 2009
    • 19798027 10.1038/nrrheum.2009.182
    • R. F. Van Vollenhoven 2009 Treatment of rheumatoid arthritis: state of the art 2009 Nat. Rev. Rheumatol. 5 531 541 19798027 10.1038/nrrheum.2009.182
    • (2009) Nat. Rev. Rheumatol. , vol.5 , pp. 531-541
    • Van Vollenhoven, R.F.1
  • 75
    • 70449643633 scopus 로고    scopus 로고
    • The potential of liposomal drug delivery for the treatment of inflammatory arthritis
    • 18926560 10.1016/j.semarthrit.2008.08.004 1:CAS:528:DC%2BD1MXhsVGmtrnM
    • A. S. Vanniasinghe V. Bender N. Manolios 2009 The potential of liposomal drug delivery for the treatment of inflammatory arthritis Semin. Arthritis Rheum. 39 182 196 18926560 10.1016/j.semarthrit.2008.08.004 1:CAS:528: DC%2BD1MXhsVGmtrnM
    • (2009) Semin. Arthritis Rheum. , vol.39 , pp. 182-196
    • Vanniasinghe, A.S.1    Bender, V.2    Manolios, N.3
  • 76
    • 0023118130 scopus 로고
    • Protein traffic in human synovial effusions
    • DOI 10.1002/art.1780300108
    • W. J. Wallis P. A. Simkin W. B. Nelp 1987 Protein traffic in human synovial effusions Arthritis Rheum. 30 57 63 3814198 10.1002/art.1780300108 1:STN:280:DyaL2s7ivVaksA%3D%3D (Pubitemid 17007261)
    • (1987) Arthritis and Rheumatism , vol.30 , Issue.1 , pp. 57-63
    • Wallis, W.J.1    Simkin, P.A.2    Nelp, W.B.3
  • 77
    • 33847214593 scopus 로고    scopus 로고
    • Novel dexamethasone-HPMA copolymer conjugate and its potential application in treatment of rheumatoid arthritis
    • Wang, D., Miller, S. C., Liu, X. M., Anderson, B., Wang, X. S., and Goldring, S. R., Novel dexamethasone-HPMA copolymer conjugate and its potential application in treatment of rheumatoid arthritis. Arthritis Res. Ther., 9, R2 (2007).
    • (2007) Arthritis Res. Ther. , vol.9
    • Wang, D.1    Miller, S.C.2    Liu, X.M.3    Anderson, B.4    Wang, X.S.5    Goldring, S.R.6
  • 79
    • 39449117736 scopus 로고    scopus 로고
    • Injectable actarit-loaded solid lipid nanoparticles as passive targeting therapeutic agents for rheumatoid arthritis
    • DOI 10.1016/j.ijpharm.2007.10.014, PII S0378517307008435
    • J. Ye Q. Wang X. Zhou N. Zhang 2008 Injectable actaritloaded solid lipid nanoparticles as passive targeting therapeutic agents for rheumatoid arthritis Int. J. Pharm. 352 273 279 18054182 10.1016/j.ijpharm.2007.10.014 1:CAS:528:DC%2BD1cXitlWhtrc%3D (Pubitemid 351273921)
    • (2008) International Journal of Pharmaceutics , vol.352 , Issue.1-2 , pp. 273-279
    • Ye, J.1    Wang, Q.2    Zhou, X.3    Zhang, N.4
  • 80
    • 77955607302 scopus 로고    scopus 로고
    • Factors that control the circulation time of nanoparticles in blood: Challenges, solutions and future prospects
    • 20618151 10.2174/138161210791920496 1:CAS:528:DC%2BC3cXhtFertrfI
    • J. W. Yoo E. Chambers S. Mitragotri 2010 Factors that control the circulation time of nanoparticles in blood: challenges, solutions and future prospects Curr. Pharm. Des. 16 2298 2307 20618151 10.2174/138161210791920496 1:CAS:528:DC%2BC3cXhtFertrfI
    • (2010) Curr. Pharm. Des. , vol.16 , pp. 2298-2307
    • Yoo, J.W.1    Chambers, E.2    Mitragotri, S.3
  • 81
    • 74349124409 scopus 로고    scopus 로고
    • Endocytosis and Intracellular Distribution of PLGA Particles in Endothelial Cells: Effect of Particle Geometry
    • 21590886 10.1002/marc.200900790 1:CAS:528:DC%2BC3cXos1Gjsw%3D%3D
    • J. W. Yoo N. Doshi S. Mitragotri 2010 Endocytosis and Intracellular Distribution of PLGA Particles in Endothelial Cells: Effect of Particle Geometry Macromol. Rapid Commun. 31 142 148 21590886 10.1002/marc.200900790 1:CAS:528:DC%2BC3cXos1Gjsw%3D%3D
    • (2010) Macromol. Rapid Commun. , vol.31 , pp. 142-148
    • Yoo, J.W.1    Doshi, N.2    Mitragotri, S.3
  • 82
    • 77954937488 scopus 로고    scopus 로고
    • Polymer particles that switch shape in response to a stimulus
    • 20547873 10.1073/pnas.1000346107 1:CAS:528:DC%2BC3cXot1eksrg%3D
    • J. W. Yoo S. Mitragotri 2010 Polymer particles that switch shape in response to a stimulus Proc. Natl. Acad. Sci. U. S. A. 107 11205 11210 20547873 10.1073/pnas.1000346107 1:CAS:528:DC%2BC3cXot1eksrg%3D
    • (2010) Proc. Natl. Acad. Sci. U. S. A. , vol.107 , pp. 11205-11210
    • Yoo, J.W.1    Mitragotri, S.2
  • 83
    • 81355147743 scopus 로고    scopus 로고
    • Adaptive micro and nanoparticles: Temporal control over carrier properties to facilitate drug delivery
    • 21605607 10.1016/j.addr.2011.05.004 1:CAS:528:DC%2BC3MXhsV2lsrzF
    • J. W. Yoo N. Doshi S. Mitragotri 2011 Adaptive micro and nanoparticles: Temporal control over carrier properties to facilitate drug delivery Adv. Drug Deliv. Rev. 63 1247 1256 21605607 10.1016/j.addr.2011.05.004 1:CAS:528:DC%2BC3MXhsV2lsrzF
    • (2011) Adv. Drug Deliv. Rev. , vol.63 , pp. 1247-1256
    • Yoo, J.W.1    Doshi, N.2    Mitragotri, S.3
  • 84
    • 79959967622 scopus 로고    scopus 로고
    • Bio-inspired, bioengineered and biomimetic drug delivery carriers
    • 21720407 10.1038/nrd3499 1:CAS:528:DC%2BC3MXotlClurs%3D
    • J. W. Yoo D. J. Irvine D. E. Discher S. Mitragotri 2011 Bio-inspired, bioengineered and biomimetic drug delivery carriers Nat. Rev. Drug Discov. 10 521 535 21720407 10.1038/nrd3499 1:CAS:528:DC%2BC3MXotlClurs%3D
    • (2011) Nat. Rev. Drug Discov. , vol.10 , pp. 521-535
    • Yoo, J.W.1    Irvine, D.J.2    Discher, D.E.3    Mitragotri, S.4
  • 85
    • 29244439986 scopus 로고    scopus 로고
    • Formation of drug-arylsulfonate complexes inside liposomes: A novel approach to improve drug retention
    • DOI 10.1016/j.jconrel.2005.10.011, PII S0168365905005456
    • I. V. Zhigaltsev N. Maurer K. Edwards G. Karlsson P. R. Cullis 2006 Formation of drug-arylsulfonate complexes inside liposomes: a novel approach to improve drug retention J. Control. Release 110 378 386 16318894 10.1016/j.jconrel.2005.10.011 1:CAS:528:DC%2BD2MXhtlert7nK (Pubitemid 41829566)
    • (2006) Journal of Controlled Release , vol.110 , Issue.2 , pp. 378-386
    • Zhigaltsev, I.V.1    Maurer, N.2    Edwards, K.3    Karlsson, G.4    Cullis, P.R.5


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