Biochemical assays for the discovery of TDP1 inhibitors

Molecular Cancer Therapeutics

Volumn 13, Issue 8, 2014, Pages 2116-2126

  Marchand, Christophe ^a   Huang, Shar Yin N ^a   Dexheimer, Thomas S ^b   Lea, Wendy A ^b   Mott, Bryan T ^b   Chergui, Adel ^a   Naumova, Alena ^a   Stephen, Andrew G ^c   Rosenthal, Andrew S ^b   Rai, Ganesha ^b   Murai, Junko ^a   Gao, Rui ^a   Maloney, David J ^b   Jadhav, Ajit ^b   Jorgensen, William L ^d   Simeonov, Anton ^b   Pommier, Yves ^a  

^a NATIONAL CANCER INSTITUTE   (United States)

^b NATIONAL INSTITUTES OF HEALTH   (United States)

^c FREDERICK NATIONAL LABORATORY FOR CANCER RESEARCH   (United States)

^d YALE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELL EXTRACT; PHOSPHODIESTERASE; PHOSPHODIESTERASE INHIBITOR; PROTEIN TDP1; PROTEIN TDP1 INHIBITOR; UNCLASSIFIED DRUG; ANTINEOPLASTIC AGENT; CAMPTOTHECIN; PEPTIDE FRAGMENT; TDP1 PROTEIN, HUMAN;

ARTICLE; CONTROLLED STUDY; DNA DAMAGE; DRUG DETERMINATION; DRUG SCREENING; ENZYME INHIBITION; HIGH THROUGHPUT SCREENING; HUMAN; MOLECULAR LIBRARY; PRIORITY JOURNAL; ANIMAL; CELL LINE; CELL SURVIVAL; CHEMISTRY; CHICKEN; DRUG EFFECTS; DRUG POTENTIATION; PROCEDURES;

ANIMALS; ANTINEOPLASTIC AGENTS; CAMPTOTHECIN; CELL LINE; CELL SURVIVAL; CHICKENS; DRUG SCREENING ASSAYS, ANTITUMOR; DRUG SYNERGISM; HUMANS; PEPTIDE FRAGMENTS; PHOSPHODIESTERASE INHIBITORS; PHOSPHORIC DIESTER HYDROLASES;

EID: 84905653295     PISSN: 15357163     EISSN: 15388514     Source Type: Journal    
DOI: 10.1158/1535-7163.MCT-13-0952     Document Type: Article

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