SUMO modification of the neuroprotective protein TDP1 facilitates chromosomal single-strand break repair

Nature Communications

Volumn 3, Issue , 2012, Pages

  Hudson, Jessica J R ^a   Chiang, Shih Chieh ^a   Wells, Owen S ^a   Rookyard, Chris ^a   El Khamisy, Sherif F ^a,b  

^a UNIVERSITY OF SUSSEX   (United Kingdom)

^b Ain Shams University   (Egypt)

Author keywords

[No Author keywords available]

Indexed keywords

LYSINE; PHOSPHODIESTERASE; SUMO PROTEIN; TYROSYL DNA PHOSPHODIESTERASE 1; UNCLASSIFIED DRUG; DNA TOPOISOMERASE; GREEN FLUORESCENT PROTEIN; MUTANT PROTEIN; SUMO 1 PROTEIN; TDP1 PROTEIN, HUMAN;

ARTICLE; CHROMOSOME PAIRING; CONTROLLED STUDY; DNA DAMAGE; DNA MODIFICATION; DNA STRAND BREAKAGE; DNA TRANSCRIPTION; ENZYME ACTIVITY; GENE MUTATION; GENOTOXICITY; HUMAN; HUMAN CELL; MAMMAL CELL; NEUROPROTECTION; OXIDATIVE STRESS; SINGLE STRAND BREAK; SUMOYLATION; BINDING SITE; CELL LINE; CELL STRAIN HEK293; CHEMISTRY; DEGENERATIVE DISEASE; DNA REPAIR; GENETIC TRANSCRIPTION; GENETICS; METABOLISM; SINGLE STRANDED DNA BREAK;

MAMMALIA;

BINDING SITES; CELL LINE; DNA BREAKS, SINGLE-STRANDED; DNA DAMAGE; DNA REPAIR; DNA TOPOISOMERASES, TYPE I; GREEN FLUORESCENT PROTEINS; HEK293 CELLS; HUMANS; MUTANT PROTEINS; NEURODEGENERATIVE DISEASES; OXIDATIVE STRESS; PHOSPHORIC DIESTER HYDROLASES; SUMO-1 PROTEIN; SUMOYLATION; TRANSCRIPTION, GENETIC;

EID: 84859186894     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/ncomms1739     Document Type: Article

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