Mechanism of repair of 5′-topoisomerase II-DNA adducts by mammalian tyrosyl-DNA phosphodiesterase 2

Nature Structural and Molecular Biology

Volumn 19, Issue 12, 2012, Pages 1363-1371

  Schellenberg, Matthew J ^a   Appel, C Denise ^a   Adhikari, Sanjay ^b   Robertson, Patrick D ^a   Ramsden, Dale A ^c   Williams, R Scott ^a  

^a NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES   (United States)

^b GEORGETOWN UNIVERSITY   (United States)

^c UNIVERSITY OF NORTH CAROLINA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DNA TOPOISOMERASE (ATP HYDROLYSING); ENDONUCLEASE; EXONUCLEASE; NUCLEASE; PHOSPHATASE; PHOSPHODIESTERASE; SINGLE STRANDED DNA; TYROSYL DNA PHOSPHODIESTERASE 2; UNCLASSIFIED DRUG;

ARTICLE; CATALYSIS; DNA ADDUCT; DNA BINDING; DNA DAMAGE; DNA REPAIR; ENZYME STRUCTURE; MOUSE; MUTATIONAL ANALYSIS; NONHUMAN; PRIORITY JOURNAL; STRUCTURE ANALYSIS;

ANIMALS; CATALYSIS; CRYSTALLOGRAPHY, X-RAY; DNA ADDUCTS; DNA REPAIR; DNA TOPOISOMERASES, TYPE II; MICE; MODELS, MOLECULAR; PHOSPHORIC DIESTER HYDROLASES;

MAMMALIA;

EID: 84870831603     PISSN: 15459993     EISSN: 15459985     Source Type: Journal    
DOI: 10.1038/nsmb.2418     Document Type: Article

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