Variant toll-like receptor4 (Asp299Gly and Thr399Ile Alleles) and toll-like receptor2 (Arg753Gln and Arg677Trp Alleles) in colorectal cancer

Iranian Journal of Allergy, Asthma and Immunology

Volumn 10, Issue 2, 2011, Pages 91-99

  Davoodi, Homa ^a,b   Seow, Hgne Fgno ^b  

^a GOLESTAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^b UNIVERSITY PUTRA MALAYSIA   (Malaysia)

Author keywords

Colorectal cancer; Polymorphisms; Toll like receptors

Indexed keywords

ASPARTIC ACID; GLUTAMINE; GLYCINE; ISOLEUCINE; THREONINE; TOLL LIKE RECEPTOR 2; TOLL LIKE RECEPTOR 4; TRYPTOPHAN;

ADULT; ALLELE; ARTICLE; CANCER PATIENT; CANCER RISK; CANCER SUSCEPTIBILITY; COLORECTAL CARCINOMA; CONTROLLED STUDY; DNA DETERMINATION; DNA ISOLATION; GENE EXPRESSION; GENETIC POLYMORPHISM; GENETIC VARIABILITY; GENOTYPE; HETEROZYGOSITY; HUMAN; HUMAN CELL; INCIDENCE; INNATE IMMUNITY; MAJOR CLINICAL STUDY; MALAYSIA; POLYMERASE CHAIN REACTION; PSEUDOGENE; RESTRICTION FRAGMENT LENGTH POLYMORPHISM; WILD TYPE;

ADULT; ALLELES; CELL LINE, TUMOR; COLORECTAL NEOPLASMS; FEMALE; HUMANS; MALE; MIDDLE AGED; POLYMORPHISM, GENETIC; TOLL-LIKE RECEPTOR 2; TOLL-LIKE RECEPTOR 4;

EID: 79959235834     PISSN: 17351502     EISSN: 17355249     Source Type: Journal    
DOI: None     Document Type: Article

References (41)

1. Hawk ET, Linburg PJ, Viner JL. Epidemiology and prevention of colorectal cancer. Surg Clin North Am 2002; 82(5):905-41. (Pubitemid 35463075)
2. Balkwill F, Coussens LM. Cancer: an inflammatory link. Nature 2004; 431(7007):405-6. (Pubitemid 39329565)
3. Willett W. The search for the causes of breast and colon cancer. Nature1989; 338(6214):389-94.
4. Fearon ER, Vogelstein B. A genetic model for colorectal tumorigenesis. Cell 1990; 61(5):759-67.
5. Reddy B, Engle A, Katsifis S, Simi B, Bartram HP, Perrino P, et al. Biochemical epidemiology of colon cancer: effect of types of dietary fiber on fecal mutagens, acid, and neutral sterols in healthy subjects. Cancer Res 1989; 49(16):4629-35. (Pubitemid 19208372)
6. Coussens LM, Werb Z. Inflammation and cancer. Nature 2002; 420()6917:860-7. (Pubitemid 36019639)
7. Robinson SC, Coussens LM. Soluble mediators of inflammation during tumor development. Adv Cancer Res 2005; 93:159-87. (Pubitemid 41557275)
8. Seril DN, Lia J, Yang GY, Yang CS. Oxidative stress and ulcerative colitis associated carcinogenesis: studies in humans and animal models. Carcinogenesis 2003; 24(3):353-62. (Pubitemid 36432628)
9. Itzkowitz SH, Yio X. Inflammation and cancer IV. Colorectal cancer in inflammatory bowel disease: the role of inflammation. Am J Physiol Gastrointest Liver Physiol 2004; 287(1):G7-17.
10. Kelly MG, Alvero AB, Chen R, Silasi DA, Abrahams VM, Chan S, et al. TLR-4 Signaling Promotes Tumor Growth and Paclitaxel Chemoresistance in Ovarian Cancer. Cancer Res 2006; 66(7):3859-68.
11. Kopp E, Medzhitov R. Recognition of microbial infection by Toll-like receptors. Curr Opin Immunol 2003; 15(4):396-401. (Pubitemid 36930075)
12. Akira S, Akeda K. Toll-like receptor signaling. Nat Immunol 2004; 4(7):499-511.
13. De Visser KE, Coussens LM. The interplay between innate and adaptive immunity regulates cancer development. Cancer Immunol Immunother 2005; 54(11):1143-52. (Pubitemid 41396818)
14. Takeuchi O, hoshino T, kawai H, sanjo H, takada T, ogawa K, et al. Differential roles of TLR2 and TLR4 in recognition of gram-negative and gram-positive bacterial cell wall components. Immunity 1999; 11(4):443-51.
15. Arbour NC, Lorenz E, Schutte BC, Zabner J, Kline JN, Jones M, et al. TLR4 mutations are associated with endotoxin hyporesponsiveness in humans. Nat Genet 2000; 25(2):187-91. (Pubitemid 30394990)
16. Zheng SL, Augustsson-Bälter K, Chang B, Hedelin M, Li L, Adami HO, et al. Sequence variants of toll-like receptor 4 are associated with prostate cancer risk: results from the Cancer Prostate in Sweden Study. Cancer Res 2004; 64(8):2918-22. (Pubitemid 38500633)
17. Chen YC, Giovannucci E, Lazarus R, Kraft P, Ketkar S, Hunter DJ. Sequence variants of Toll-like receptor 4 and susceptibility to prostate cancer. Cancer Res 2005; 65(24):11771-8. (Pubitemid 41821739)
18. Achyuta BR, Ghoshalb UC, Moorchung N, Mittal B. Association of Toll-like receptor-4 (Asp299Gly and Thr399Ileu) gene polymorphisms with gastritis and precancerous lesions. Hum Immunol 2007; 68(11):901-7. (Pubitemid 350235728)
19. Garza-Gonzalez E, Bosques-Padilla FJ, Mendoza-Ibarra SI, Flores-Gutierrez JP, Maldonado-Garza HJ, Perez-Perez GI. Assessment of the toll-like receptor 4 Asp299gly, thr399Ile and interleukin-8 -251 polymorphisms in the risk for the development of distal gastric cancer. BMC Cancer 2007; 7:70-5.
20. Hold GL, Rabkin CS, Chow WH, Smith MG, Gammon MD, Risch HA, et al. A functional polymorphism of toll-like receptor 4 gene increases risk of gastric carcinoma and its precursors. Gastroenterology 2007; 132(3):905-12. (Pubitemid 46440859)
21. Weighardt H, Kaiser-Moore S, Vabulas RM, Kirschning CJ, Wagner H, Holzmann B. Cutting edge: Myeloid differentiation factor 88 deficiency improves resistance against sepsis caused by polymicrobial infection. J Immunol 2002; 169(6):2823-7. (Pubitemid 35013119)
22. Simpson JL, Grissell TV, Douwes J, Scott RJ, Boyle MJ, Gibson PG. Innate immune activation in neutrophilic asthma and bronchiectasis. Thorax 2007; 62(3):211-8. (Pubitemid 46579799)
23. De Kleijn D, Pasterkamp G. Toll-like receptors in cardiovascular diseases. Cardiovasc Res 2003; 60(1):58-67. (Pubitemid 38373476)
24. Rock FL, Hardiman G, Timans JC, Kastelein RA, Bazan JF. A family of human receptors structurally related to DrosophilaToll. Proc Natl Acad Sci USA 1998; 95(2):588-93. (Pubitemid 28083787)
25. Arbour NC, Lorenz E, Schutte BC, Zabner J, Kline J N, Jones M, et al. TLR4 mutations are associated with endotoxin hyporesponsiveness in humans. Nat Genet 2000; 25(2):187-91. (Pubitemid 30394990)
26. Ferwerda B, McCall MB, Verheijen K, Kullberg BJ, van der Ven AJ, Van der Meer JW, et al. Functional consequences of toll-like receptor 4 polymorphisms. Mol Med 2008; 14(5-6):346-52. (Pubitemid 351785708)
27. Kang TJ, Chae GT. Detection of Toll-like receptor 2 (TLR2) mutation in the lepromatous leprosy patients. FEMS Immunol Med Microbiol 2001; 31(1):53-8.
28. Boraska Jelavic T, Barisic M, Drmic Hofman I, Boraska V, Vrdoljak E, Peruzovic M, et al. Microsatelite GT polymorphism in the toll-like receptor 2 is associated with colorectal cancer. Clin Genet 2006; 70(2):156-60. (Pubitemid 44028102)
29. Cheng PL, Eng HL, Chou MH, You HL, Lin TM. Genetic polymorphisms of viral infection-associated Toll-like receptors in Chinese population. Transl Res 2007; 150(5):311-8.
30. Franchimont D, Vermeire S, El Housni H, Pierik M, Van Steen K, Gustot T, et al. Deficient host-bacteria interactions in inflammatory bowel disease? The toll-like receptor (TLR)-4 Asp299gly polymorphism is associated with Crohn's disease and ulcerative colitis. Gut 2004; 53(7):987-92. (Pubitemid 38824157)
31. Torok HP, Glas J, Tonenchi L, Mussack T, Folwaczny C. Polymorphisms of the lipopolysaccharide-signaling complex in inflammatory bowel disease: association of a mutation in the Toll-like receptor 4 gene with ulcerative colitis. Clin Immunol 2004; 112(1):85-91. (Pubitemid 38781061)
32. Gazouli M, Mantzaris G, Kotsinas A, Zacharatos P, Papalambros E, Archimandritis A, et al. Association between polymorphisms in the Toll-like receptor 4, CD14, and CARD15/NOD2 and inflammatory bowel disease in the Greek population. World J Gastroenterol 2005; 11(5):681-5. (Pubitemid 40220757)
33. Gree CE, Wheeler CM, Manos M. Sample preparation and PCR amplification from paraffin-embedded tissues. Genome Res 1994; 3(6):113-22.
34. Folwaczny M, Glas J, Torok HP, Limbersky O, Folwaczny C. Toll-like receptor (TLR) 2 and 4 mutations in periodontal disease. Clin Exp Immunol 2004; 135(2):330-5. (Pubitemid 38177975)
35. Lorenz E, Mira JP, Frees KL, Schwartz DA. Relevance of Mutations in the TLR4 Receptor in Patients with Gram-Negative Septic Shock. Arch Intern Med 2002; 162(9):1028-32. (Pubitemid 34492532)
36. Yoon HJ, Choi JY, Kim CO, Park YS, Kim MS, Kim YK, et al. Lack of Toll- like receptor 4 and 2 polymorphisms in Korean patients with bacteremia. J Korean Med Sci 2006; 21(6):979-82.
37. Kang ES, Lee J. Genotypic analysis of Asp299Gly and Thr399Ile polymorphism of Toll-like receptor 4 in systemic autoimmune diseases of Korean population. Rheumatol Int 2007; 27(9):887-9. (Pubitemid 46906644)
38. Liang XH, Cheung W, Heng CK, Wang DY. Absence of the Toll-like receptor 4 gene polymorphisms Asp299Gly and Thr399Ile in Singaporean Chinese. Ther Clin Risk Manag 2005; 1(3):243-6.
39. Pandey S, Mittal RD, Srivastava M, Srivastava K, Singh S, Srivastava S, et al. Impact of Toll-like receptors [TLR] 2 (-196 to -174 del) and TLR 4 (Asp299Gly, Thr399Ile) in cervical cancer susceptibility in North Indian women. Gynecol Oncol 2009; 114(3):501-5.
40. Malhotra D, Relhan V, Reddy BS, Bamezai R. TLR2 Arg677Trp polymorphism in leprosy: revisited. Hum Genet 2005; 116(5):413-5. (Pubitemid 40521120)
41. Nishimura M, Naito S. Tissue-specific mRNA expression profiles of human toll-like receptors and related genes. Biol Pharm Bull 2005; 28(5):886-92. (Pubitemid 40740661)