De Novo Design and Experimental Characterization of Ultrashort Self-Associating Peptides

PLoS Computational Biology

Volumn 10, Issue 7, 2014, Pages

  Smadbeck, James ^a   Chan, Kiat Hwa ^b   Khoury, George A ^a   Xue, Bo ^c   Robinson, Robert C ^c   Hauser, Charlotte A E ^b   Floudas, Christodoulos A ^a  

^a Princeton University   (United States)

^b INSTITUTE OF BIOENGINEERING AND NANOTECHNOLOGY   (Singapore)

^c INSTITUTE OF MOLECULAR AND CELL BIOLOGY   (Singapore)

Author keywords

[No Author keywords available]

Indexed keywords

ASSOCIATION REACTIONS; HYDROGELS; POTENTIAL ENERGY; SINGLE CRYSTALS; X RAY CRYSTALLOGRAPHY;

AMYLOID DISEASE; BIOLOGICALLY INSPIRED MATERIAL; CYTOSKELETONS; DE NOVO DESIGN; DE NOVO PEPTIDE DESIGN; DESIGN FRAMEWORKS; EXPERIMENTAL CHARACTERIZATION; MULTIMERIC; SELF-ASSOCIATIONS; TRI-PEPTIDES;

PEPTIDES;

ALANINE; ISOLEUCINE; LEUCINE; METHIONINE; PEPTIDE; PHENYLALANINE; SELF ASSOCIATING PEPTIDE; TRIPEPTIDE; TRYPTOPHAN; TYROSINE; UNCLASSIFIED DRUG; HYDROGEL; PROTEIN AGGREGATE;

AMINO ACID SEQUENCE; AMINO TERMINAL SEQUENCE; ARTICLE; BETA SHEET; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; CRYSTAL STRUCTURE; ELECTRON MICROSCOPY; FIELD EMISSION SCANNING ELECTRON MICROSCOPY; HYDROGEL; HYDROGEN BOND; HYDROPHOBICITY; POINT MUTATION; PROCESS OPTIMIZATION; PROTEIN AGGREGATION; PROTEIN ASSEMBLY; PROTEIN CONFORMATION; PROTEIN FOLDING; PROTEIN FUNCTION; PROTEIN INTERACTION; PROTEIN MOTIF; PROTEIN STRUCTURE; X RAY CRYSTALLOGRAPHY; X RAY DIFFRACTION; BIOLOGY; CHEMISTRY; METABOLISM; MOLECULAR DYNAMICS; PROTEIN MULTIMERIZATION; VISCOSITY;

COMPUTATIONAL BIOLOGY; CRYSTALLOGRAPHY, X-RAY; HYDROGEL; MOLECULAR DYNAMICS SIMULATION; PEPTIDES; PROTEIN AGGREGATES; PROTEIN MULTIMERIZATION; VISCOSITY;

EID: 84905474731     PISSN: 1553734X     EISSN: 15537358     Source Type: Journal    
DOI: 10.1371/journal.pcbi.1003718     Document Type: Article

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