Cellular unfolded protein response against viruses used in gene therapy

Frontiers in Microbiology

Volumn 5, Issue MAY, 2014, Pages

  Sen, Dwaipayan ^a   Balakrishnan, Balaji ^a   Jayandharan, Giridhara R ^a  

^a CHRISTIAN MEDICAL COLLEGE   (India)

Author keywords

Chaperones; ER homeostasis; ER stress; Gene therapy; UPR; Viral vectors

Indexed keywords

ACTIVATING TRANSCRIPTION FACTOR 6; ADENOVIRUS VECTOR; APOPTOSIS SIGNAL REGULATING KINASE 1; ARGONAUTE 1 PROTEIN; CALCIUM ION; CHAPERONE; DNA DAMAGE INDUCIBLE PROTEIN 34; DNA DIRECTED RNA POLYMERASE III; GROWTH ARREST AND DNA DAMAGE INDUCIBLE PROTEIN 153; HERPESVIRUS VECTOR; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INOSITOL REQUIRING PROTEIN 1; INTERLEUKIN 1ALPHA; INTERLEUKIN 6; LENTIVIRUS VECTOR; MESSENGER RNA; PEPTIDES AND PROTEINS; PROTEIN BCL 2; PROTEIN IRE1; PROTEIN KINASE LIKE ENDOPLASMIC RETICULUM KINASE; PROTEIN KINASE R; PROTEINASE; RETROVIRUS VECTOR; STRESS ACTIVATED PROTEIN KINASE; TUMOR NECROSIS FACTOR ALPHA; TUMOR NECROSIS FACTOR RECEPTOR ASSOCIATED FACTOR 2; UNCLASSIFIED DRUG; UNFOLDED PROTEIN; UNINDEXED DRUG; VIRUS VECTOR; X BOX BINDING PROTEIN1;

ANTIGEN RECOGNITION; APOPTOSIS; ARTICLE; AUTOPHAGY; CELL DEATH; CELL DESTRUCTION; CLINICAL TRIAL (TOPIC); ENDOPLASMIC RETICULUM STRESS; GENE THERAPY; HOMEOSTASIS; HUMAN; INFLAMMATION; INTRACELLULAR SIGNALING; NONHUMAN; RNA TRANSLATION; SIGNAL TRANSDUCTION; UNFOLDED PROTEIN RESPONSE; UPREGULATION; VIRAL GENE DELIVERY SYSTEM; VIRUS REPLICATION;

EID: 84904858917     PISSN: None     EISSN: 1664302X     Source Type: Journal    
DOI: 10.3389/fmicb.2014.00250     Document Type: Article

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