Cytomegalovirus Downregulates IRE1 to Repress the Unfolded Protein Response

PLoS Pathogens

Volumn 9, Issue 8, 2013, Pages

  Stahl, Sebastian ^a,b,i   Burkhart, Julia M ^c   Hinte, Florian ^a   Tirosh, Boaz ^d   Mohr, Hermine ^e   Zahedi, René P ^c   Sickmann, Albert ^c,f   Ruzsics, Zsolt ^e,g   Budt, Matthias ^b   Brune, Wolfram ^a,b,h  

^a LEIBNIZ INSTITUTE FOR EXPERIMENTAL VIROLOGY   (Germany)

^b ROBERT KOCH INSTITUTE   (Germany)

^c LEIBNIZ INSTITUT FÜR ANALYTISCHE WISSENSCHAFTEN ISAS E V   (Germany)

^d HEBREW UNIVERSITY OF JERUSALEM   (Israel)

^e UNIVERSITY OF MUNICH   (Germany)

^f RUHR UNIVERSITY BOCHUM   (Germany)

^g German Center for Infection Research   (Germany)

^h German Center for Infection Research (DZIF)   (Germany)

ⁱ ROCHE DIAGNOSTICS GMBH   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CHAPERONE; PROTEIN IRE1; PROTEIN M50; TUNICAMYCIN; UNCLASSIFIED DRUG; VIRUS PROTEIN; X BOX BINDING PROTEIN 1; DNA BINDING PROTEIN; ERN2 PROTEIN, HUMAN; ERN2 PROTEIN, MOUSE; MEMBRANE PROTEIN; PROTEIN SERINE THREONINE KINASE; REGULATORY FACTOR X TRANSCRIPTION FACTORS; RIBONUCLEASE; TRANSCRIPTION FACTOR;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; CYTOMEGALOVIRUS; DOWN REGULATION; ENDOPLASMIC RETICULUM ASSOCIATED DEGRADATION; ENZYME REPRESSION; HUMAN; HUMAN CELL; IMMUNOBLOTTING; IMMUNOFLUORESCENCE; IMMUNOPRECIPITATION; MASS SPECTROMETRY; NONHUMAN; NUCLEOTIDE SEQUENCE; PHOSPHORYLATION; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN FOLDING; PROTEIN INTERACTION; PROTEIN LOCALIZATION; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA SPLICING; SIGNAL TRANSDUCTION; UNFOLDED PROTEIN RESPONSE; UPREGULATION; 3T3 CELL LINE; ANIMAL; BIOSYNTHESIS; CYTOMEGALOVIRUS INFECTION; GENETICS; METABOLISM; MOUSE; MUROMEGALOVIRUS; TRANSFORMED CELL LINE;

ANIMALS; CELL LINE, TRANSFORMED; CYTOMEGALOVIRUS; CYTOMEGALOVIRUS INFECTIONS; DNA-BINDING PROTEINS; DOWN-REGULATION; ENDORIBONUCLEASES; HUMANS; MEMBRANE PROTEINS; MICE; MUROMEGALOVIRUS; NIH 3T3 CELLS; PROTEIN-SERINE-THREONINE KINASES; TRANSCRIPTION FACTORS; UNFOLDED PROTEIN RESPONSE; VIRAL STRUCTURAL PROTEINS;

EID: 84883312419     PISSN: 15537366     EISSN: 15537374     Source Type: Journal    
DOI: 10.1371/journal.ppat.1003544     Document Type: Article

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