메뉴 건너뛰기




Volumn 4, Issue 4, 1997, Pages 367-374

Cloning of human IL-12 p40 and p35 DNA into the Semliki Forest virus vector: Expression of IL-12 in human tumor cells

Author keywords

Gene therapy; Human IL 12; Human tumor cells; SFV vector

Indexed keywords

COMPLEMENTARY DNA; INTERLEUKIN 12; MESSENGER RNA;

EID: 8244238389     PISSN: 09697128     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.gt.3300409     Document Type: Article
Times cited : (29)

References (32)
  • 1
    • 0028052808 scopus 로고
    • Cytokine gene transfer in tumor inhibition and tumor therapy: Where are we now?
    • Colombo MP, Forni G. Cytokine gene transfer in tumor inhibition and tumor therapy: where are we now? Immunol Today 1993; 15: 48-51.
    • (1993) Immunol Today , vol.15 , pp. 48-51
    • Colombo, M.P.1    Forni, G.2
  • 2
    • 0024467154 scopus 로고
    • Identification and purification of natural killer cell stimulatory factor (NKSF), a cytokine with multiple biologic effects on human lymphocytes
    • Kobayashi M et al. Identification and purification of natural killer cell stimulatory factor (NKSF), a cytokine with multiple biologic effects on human lymphocytes. J Exp Med 1989; 170: 827-844.
    • (1989) J Exp Med , vol.170 , pp. 827-844
    • Kobayashi, M.1
  • 3
    • 0025028960 scopus 로고
    • Purification to homogeneity and partial characterization of cytotoxic lymphocyte maturation factor from human B-lymphoblastoid cells
    • Stern AS et al. Purification to homogeneity and partial characterization of cytotoxic lymphocyte maturation factor from human B-lymphoblastoid cells. Proc Natl Acad Sci USA 1990; 87: 6808-6812.
    • (1990) Proc Natl Acad Sci USA , vol.87 , pp. 6808-6812
    • Stern, A.S.1
  • 4
    • 0025808629 scopus 로고
    • Coexpression of two distinct genes is required to generate secreted bioactive cytotoxic lymphocyte maturation factor
    • Gubler U et al. Coexpression of two distinct genes is required to generate secreted bioactive cytotoxic lymphocyte maturation factor. Proc Natl Acad Sci USA 1991; 88: 4143-4147.
    • (1991) Proc Natl Acad Sci USA , vol.88 , pp. 4143-4147
    • Gubler, U.1
  • 5
    • 0026701132 scopus 로고
    • Production of natural killer cell stimulatory factor (NKSF/IL-12) by peripheral blood mononuclear cells
    • D'Andrea A et al. Production of natural killer cell stimulatory factor (NKSF/IL-12) by peripheral blood mononuclear cells. J Exp Med 1992; 176: 1387-1398.
    • (1992) J Exp Med , vol.176 , pp. 1387-1398
    • D'Andrea, A.1
  • 6
    • 0026605457 scopus 로고
    • The IL-12 receptor. II. Distribution and regulation of receptor expression
    • Desai BB et al. The IL-12 receptor. II. Distribution and regulation of receptor expression J Immunol 1992; 148: 3125-3132.
    • (1992) J Immunol , vol.148 , pp. 3125-3132
    • Desai, B.B.1
  • 7
    • 0028235663 scopus 로고
    • Expression cloning of a human IL-12 receptor component. A new member of the cytokine receptor super-family with strong homologv to gp130
    • Chua AO et al. Expression cloning of a human IL-12 receptor component. A new member of the cytokine receptor super-family with strong homologv to gp130. J Immunol 1994; 153: 128-136.
    • (1994) J Immunol , vol.153 , pp. 128-136
    • Chua, A.O.1
  • 8
    • 0027409793 scopus 로고
    • Natural killer cell stimulator factor (NKSF/IL-12) induces Th1-type specific immune responses and inhibits the development of IL-4 producing Th cells
    • Manetti R et al. Natural killer cell stimulator factor (NKSF/IL-12) induces Th1-type specific immune responses and inhibits the development of IL-4 producing Th cells. J Exp Med 1993; 177: 1199-1204.
    • (1993) J Exp Med , vol.177 , pp. 1199-1204
    • Manetti, R.1
  • 9
    • 0028043326 scopus 로고
    • Interleukin-12: A cytokine produced by antigen-presenting cells with immunoregulatory functions in the generation of T-helper cells type 1 and cytotoxic lymphocytes
    • Trinchieri G. Interleukin-12: a cytokine produced by antigen-presenting cells with immunoregulatory functions in the generation of T-helper cells type 1 and cytotoxic lymphocytes. Blood 1994; 84: 4008-4027.
    • (1994) Blood , vol.84 , pp. 4008-4027
    • Trinchieri, G.1
  • 10
    • 0025819340 scopus 로고
    • Induction of IFNγ production by NK cell stimulatory factor (NKSF): Characterization of the responder cells and synergy with other inducers
    • Chan SH et al. Induction of IFNγ production by NK cell stimulatory factor (NKSF): characterization of the responder cells and synergy with other inducers. J Exp Med 1991; 173: 869-879.
    • (1991) J Exp Med , vol.173 , pp. 869-879
    • Chan, S.H.1
  • 11
    • 0028096083 scopus 로고
    • Administration of recombinant IL-12 to normal mice enhances cytolytic lymphocyte activity and induces production of IFNγ in vivo
    • Gately MK et al. Administration of recombinant IL-12 to normal mice enhances cytolytic lymphocyte activity and induces production of IFNγ in vivo. Int Immunol 1994; 6: 157-167.
    • (1994) Int Immunol , vol.6 , pp. 157-167
    • Gately, M.K.1
  • 12
    • 0027239503 scopus 로고
    • Antitumor and antimetastatic activity of interleukin-12 against murine tumors
    • Brunda MJ et al. Antitumor and antimetastatic activity of interleukin-12 against murine tumors. J Exp Med 1993; 178: 1123-1130.
    • (1993) J Exp Med , vol.178 , pp. 1123-1130
    • Brunda, M.J.1
  • 13
    • 0028897739 scopus 로고
    • Interleukin-12 inhibits angiogenesis in vivo
    • Voest EE et al. Interleukin-12 inhibits angiogenesis in vivo. J Natl Cancer Inst 1995; 87: 581-588.
    • (1995) J Natl Cancer Inst , vol.87 , pp. 581-588
    • Voest, E.E.1
  • 14
    • 0027953555 scopus 로고
    • Fibroblasts genetically engineered to secrete interleukin-12 can suppress tumor growth and induce antitumor immunity to a murine melanoma in vivo
    • Tahara H et al. Fibroblasts genetically engineered to secrete interleukin-12 can suppress tumor growth and induce antitumor immunity to a murine melanoma in vivo. Cancer Res 1994; 54: 182-189.
    • (1994) Cancer Res , vol.54 , pp. 182-189
    • Tahara, H.1
  • 15
    • 0027595949 scopus 로고
    • The basic science of gene therapy
    • Mulligan RC. The basic science of gene therapy. Science 1993; 200: 926-932.
    • (1993) Science , vol.200 , pp. 926-932
    • Mulligan, R.C.1
  • 16
    • 0029053343 scopus 로고
    • Effective eradication of established murine tumors with interleukin-12 (IL-12) gene therapy using a polycistronic retroviral vector
    • Tahara H et al. Effective eradication of established murine tumors with interleukin-12 (IL-12) gene therapy using a polycistronic retroviral vector. J Immunol 1995; 154: 6466-6474.
    • (1995) J Immunol , vol.154 , pp. 6466-6474
    • Tahara, H.1
  • 17
    • 0024988334 scopus 로고
    • Gene transfer into humans. Immunotherapy of patients with advanced melanoma, using tumor-infiltrating lymphocytes modified by retroviral gene transduction
    • Rosenberg SA et al. Gene transfer into humans. Immunotherapy of patients with advanced melanoma, using tumor-infiltrating lymphocytes modified by retroviral gene transduction. New Engl J Med 1990; 323: 570-578.
    • (1990) New Engl J Med , vol.323 , pp. 570-578
    • Rosenberg, S.A.1
  • 18
    • 0025604195 scopus 로고
    • Retroviral vector-mediated γ-interferon gene transfer into tumor cells generates potent and long-lasting antitumor immunity
    • Gansbacher B et al. Retroviral vector-mediated γ-interferon gene transfer into tumor cells generates potent and long-lasting antitumor immunity. Cancer Res 1990; 50: 7820-7825.
    • (1990) Cancer Res , vol.50 , pp. 7820-7825
    • Gansbacher, B.1
  • 19
    • 14744304517 scopus 로고
    • A new generation of animal cell expression vectors based on the Semliki Forest virus replicon
    • Liljeström P, Garoff H. A new generation of animal cell expression vectors based on the Semliki Forest virus replicon. Bio/Technology 1991; 9: 1356-1361.
    • (1991) Bio/Technology , vol.9 , pp. 1356-1361
    • Liljeström, P.1    Garoff, H.2
  • 20
    • 0028027482 scopus 로고
    • Alphavirus expression systems
    • Liljeström P. Alphavirus expression systems. Curr Opin Bictechnol 1994; 5: 495-500.
    • (1994) Curr Opin Bictechnol , vol.5 , pp. 495-500
    • Liljeström, P.1
  • 21
    • 0344192533 scopus 로고    scopus 로고
    • Protection against lethal simian immunodeficiency virus SIVsmmPBj14 disease by a recombinant Semliki Forest virus gp160 vaccine and by a gp120 subunit vaccine
    • Mossman SP et al. Protection against lethal simian immunodeficiency virus SIVsmmPBj14 disease by a recombinant Semliki Forest virus gp160 vaccine and by a gp120 subunit vaccine. J Virol 1996; 70: 1953-1960.
    • (1996) J Virol , vol.70 , pp. 1953-1960
    • Mossman, S.P.1
  • 22
    • 0028173338 scopus 로고
    • Self-replicating Semliki Forest virus RNA as recombinant vaccine
    • Zhou X et al. Self-replicating Semliki Forest virus RNA as recombinant vaccine. Vaccine 1994; 12: 1510-1514.
    • (1994) Vaccine , vol.12 , pp. 1510-1514
    • Zhou, X.1
  • 23
    • 0028962824 scopus 로고
    • Generation of cytotoxic and humoral immune responses using non-replicative recombinant Semliki Forest virus
    • Zhou X et al. Generation of cytotoxic and humoral immune responses using non-replicative recombinant Semliki Forest virus. Proc Natl Acad Sci USA 1995; 92: 3009-3013.
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 3009-3013
    • Zhou, X.1
  • 24
    • 0025000864 scopus 로고
    • Interleukin-2 gene transfer into tumor cells abrogates tumorigenicity and induces protective immunity
    • Gansbacher B et al. Interleukin-2 gene transfer into tumor cells abrogates tumorigenicity and induces protective immunity. J Exp Med 1990; 172: 1217-1224.
    • (1990) J Exp Med , vol.172 , pp. 1217-1224
    • Gansbacher, B.1
  • 25
    • 0030067173 scopus 로고    scopus 로고
    • Interleukin-12, cellular and molecular immunology of an important regulatory cytokine
    • Chouaib S, Escudier B, Chehimi J. Interleukin-12, cellular and molecular immunology of an important regulatory cytokine. Eur Cytok Netw 1996; 7: 79-81.
    • (1996) Eur Cytok Netw , vol.7 , pp. 79-81
    • Chouaib, S.1    Escudier, B.2    Chehimi, J.3
  • 26
    • 0027483008 scopus 로고
    • Interleukin-12 promotes the proliferation and cytolytic maturation of immune effectors: Implication for the immunotherapy of cancer
    • Zeh HJ III, Hurd S, Storkus WJ, Lotze MT. Interleukin-12 promotes the proliferation and cytolytic maturation of immune effectors: implication for the immunotherapy of cancer. J Immunother 1993; 14: 155-161.
    • (1993) J Immunother , vol.14 , pp. 155-161
    • Zeh III, H.J.1    Hurd, S.2    Storkus, W.J.3    Lotze, M.T.4
  • 27
    • 0026530097 scopus 로고
    • Human gene therapy
    • Anderson WF. Human gene therapy. Science 1992; 256: 808-813.
    • (1992) Science , vol.256 , pp. 808-813
    • Anderson, W.F.1
  • 28
    • 0027200981 scopus 로고
    • The interleukin-12 subunit p40 specifically inhibits effects of the interleukin-12 heterodimer
    • Mattner F et al. The interleukin-12 subunit p40 specifically inhibits effects of the interleukin-12 heterodimer. Eur J Immunol 1993; 23: 2202-2208.
    • (1993) Eur J Immunol , vol.23 , pp. 2202-2208
    • Mattner, F.1
  • 29
    • 0028937785 scopus 로고
    • Cellular and humoral immune responses to viral antigens create barriers to lung-directed gene therapy with recombinant adenoviruses
    • Yang Y, Li Q, Ertl HC, Wilson J. Cellular and humoral immune responses to viral antigens create barriers to lung-directed gene therapy with recombinant adenoviruses. J Virol 1995; 69: 2004-2015.
    • (1995) J Virol , vol.69 , pp. 2004-2015
    • Yang, Y.1    Li, Q.2    Ertl, H.C.3    Wilson, J.4
  • 30
    • 14744292350 scopus 로고
    • Semliki Forest virus expression system: Production of conditionally infectious recombinant particles
    • Berglund P et al. Semliki Forest virus expression system: production of conditionally infectious recombinant particles. Bio/Technology 1993; 11: 916-920.
    • (1993) Bio/Technology , vol.11 , pp. 916-920
    • Berglund, P.1
  • 31
    • 0028593449 scopus 로고
    • Interleukin-12 induces the differentiation of major histocompatibility complex class I-primed cytotoxic T-lymphocyte precursors into allospecific cytotoxic effectors
    • Chouaib S et al. Interleukin-12 induces the differentiation of major histocompatibility complex class I-primed cytotoxic T-lymphocyte precursors into allospecific cytotoxic effectors. Proc Natl Acad Sci USA 1994; 91: 12659-12663.
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 12659-12663
    • Chouaib, S.1
  • 32
    • 0026431613 scopus 로고
    • Improved vectors for stable expression of foreign genes mammalian cells by use of the untranslated leader sequence from EMC virus
    • Kaufman RJ et al. Improved vectors for stable expression of foreign genes mammalian cells by use of the untranslated leader sequence from EMC virus. Nucleic Acids Res 1991; 19: 4484-4492.
    • (1991) Nucleic Acids Res , vol.19 , pp. 4484-4492
    • Kaufman, R.J.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.