메뉴 건너뛰기




Volumn 13, Issue 2, 2006, Pages 150-162

Epstein-Barr virus vector-mediated gene transfer into human B cells: Potential for antitumor vaccination

Author keywords

B cells; B CLL; EBV vecor; Gene transfer; GM CSF

Indexed keywords

GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; VIRUS VECTOR;

EID: 29944439850     PISSN: 09697128     EISSN: 14765462     Source Type: Journal    
DOI: 10.1038/sj.gt.3302602     Document Type: Article
Times cited : (22)

References (62)
  • 1
    • 0036548986 scopus 로고    scopus 로고
    • Spinning molecular immunology into successful immunotherapy
    • Pardoll DM. Spinning molecular immunology into successful immunotherapy. Nat Rev Immunol 2002; 2: 227-238.
    • (2002) Nat Rev Immunol , vol.2 , pp. 227-238
    • Pardoll, D.M.1
  • 2
    • 0035135747 scopus 로고    scopus 로고
    • Viral vectors for gene therapy: The art of turning infectious agents into vehicles of therapeutics
    • Kay MA, Glorioso JC, Naldini L. Viral vectors for gene therapy: The art of turning infectious agents into vehicles of therapeutics. Nat Med 2001; 7: 33-40.
    • (2001) Nat Med , vol.7 , pp. 33-40
    • Kay, M.A.1    Glorioso, J.C.2    Naldini, L.3
  • 3
    • 0042674185 scopus 로고    scopus 로고
    • CpG oligodeoxynucleotides enhance the capacity of adenovirus-mediated CD154 gene transfer to generate effective B-cell lymphoma vaccines
    • Rieger R, Kipps TJ. CpG oligodeoxynucleotides enhance the capacity of adenovirus-mediated CD154 gene transfer to generate effective B-cell lymphoma vaccines. Cancer Res 2003; 63: 4128-4135.
    • (2003) Cancer Res , vol.63 , pp. 4128-4135
    • Rieger, R.1    Kipps, T.J.2
  • 4
    • 4644224566 scopus 로고    scopus 로고
    • Engagement of the B-cell antigen receptor (BCR) allows efficient transduction of ZAP-70-positive primary B-CLL cells by recombinant adeno-associated virus (rAAV) vectors
    • Kofler DM, Buning H, Mayr C, Bund D, Baumert J, Hallek M et al. Engagement of the B-cell antigen receptor (BCR) allows efficient transduction of ZAP-70-positive primary B-CLL cells by recombinant adeno-associated virus (rAAV) vectors. Gene Therapy 2004; 11: 1416-1424.
    • (2004) Gene Therapy , vol.11 , pp. 1416-1424
    • Kofler, D.M.1    Buning, H.2    Mayr, C.3    Bund, D.4    Baumert, J.5    Hallek, M.6
  • 6
    • 0024375760 scopus 로고
    • Genetic analysis of immortalizing functions of Epstein-Barr virus in human B lymphocytes
    • Hammerschmidt W, Sugden B. Genetic analysis of immortalizing functions of Epstein-Barr virus in human B lymphocytes. Nature 1989; 340: 393-397.
    • (1989) Nature , vol.340 , pp. 393-397
    • Hammerschmidt, W.1    Sugden, B.2
  • 7
    • 0038243011 scopus 로고    scopus 로고
    • Latent membrane protein 1 is critical for efficient growth transformation of human B cells by Epstein-Barr virus
    • Dirmeier U, Neuhierl B, Kilger E, Reisbach G, Sandberg ML, Hammerschmidt W. Latent membrane protein 1 is critical for efficient growth transformation of human B cells by Epstein-Barr virus. Cancer Res 2003; 63: 2982-2989.
    • (2003) Cancer Res , vol.63 , pp. 2982-2989
    • Dirmeier, U.1    Neuhierl, B.2    Kilger, E.3    Reisbach, G.4    Sandberg, M.L.5    Hammerschmidt, W.6
  • 8
    • 0034660443 scopus 로고    scopus 로고
    • The Epstein-Barr virus lytic program is controlled by the co-operative functions of two transactivators
    • Feederle R, Kost M, Baumann M, Janz A, Drouet E, Hammerschmidt W et al. The Epstein-Barr virus lytic program is controlled by the co-operative functions of two transactivators. EMBO J 2000; 19: 3080-3089.
    • (2000) EMBO J , vol.19 , pp. 3080-3089
    • Feederle, R.1    Kost, M.2    Baumann, M.3    Janz, A.4    Drouet, E.5    Hammerschmidt, W.6
  • 9
    • 0027282974 scopus 로고
    • A transcription factor with homology to the AP-1 family links RNA transcription and DNA replication in the lytic cycle of Epstein-Barr virus
    • Schepers A, Pich D, Hammerschmidt W. A transcription factor with homology to the AP-1 family links RNA transcription and DNA replication in the lytic cycle of Epstein-Barr virus. Eur Mol Biol Org J 1993; 12: 3921-3929.
    • (1993) Eur Mol Biol Org J , vol.12 , pp. 3921-3929
    • Schepers, A.1    Pich, D.2    Hammerschmidt, W.3
  • 10
    • 0032493274 scopus 로고    scopus 로고
    • Propagation and recovery of intact, infectious Epstein-Barr virus from prokaryotic to human cells
    • Delecluse HJ, Hilsendegen T, Pich D, Zeidler R, Hammerschmidt W. Propagation and recovery of intact, infectious Epstein-Barr virus from prokaryotic to human cells. Proc Natl Acad Sci USA 1998; 95: 8245-8250.
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 8245-8250
    • Delecluse, H.J.1    Hilsendegen, T.2    Pich, D.3    Zeidler, R.4    Hammerschmidt, W.5
  • 11
    • 0022539087 scopus 로고
    • In vitro actions on hemopoietic cells of recombinant murine GM-CSF purified after production in Escherichia coli: Comparison with purified native GM-CSF
    • Metcalf D, Burgess AW, Johnson GR, Nicola NA, Nice EC, DeLamarter J et al. In vitro actions on hemopoietic cells of recombinant murine GM-CSF purified after production in Escherichia coli: Comparison with purified native GM-CSF. J Cell Physiol 1986; 128: 421-431.
    • (1986) J Cell Physiol , vol.128 , pp. 421-431
    • Metcalf, D.1    Burgess, A.W.2    Johnson, G.R.3    Nicola, N.A.4    Nice, E.C.5    DeLamarter, J.6
  • 12
    • 0027538181 scopus 로고
    • Vaccination with irradiated tumor cells engineered to secrete murine granulocyte-macrophage colony-stimulating factor stimulates potent, specific, and long-lasting anti-tumor immunity
    • Dranoff G, Jaffee E, Lazenby A, Golumbek P, Levitsky H, Brose K et al. Vaccination with irradiated tumor cells engineered to secrete murine granulocyte-macrophage colony-stimulating factor stimulates potent, specific, and long-lasting anti-tumor immunity. Proc Natl Acad Sci USA 1993; 90: 3539-3543.
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 3539-3543
    • Dranoff, G.1    Jaffee, E.2    Lazenby, A.3    Golumbek, P.4    Levitsky, H.5    Brose, K.6
  • 13
    • 0032546352 scopus 로고    scopus 로고
    • Dendritic cells and the control of immunity
    • Banchereau J, Steinman RM. Dendritic cells and the control of immunity. Nature 1998; 392: 245-252.
    • (1998) Nature , vol.392 , pp. 245-252
    • Banchereau, J.1    Steinman, R.M.2
  • 14
    • 0038793763 scopus 로고    scopus 로고
    • GM-CSF-secreting melanoma vaccines
    • Dranoff G. GM-CSF-secreting melanoma vaccines. Oncogene 2003; 22: 3188-3192.
    • (2003) Oncogene , vol.22 , pp. 3188-3192
    • Dranoff, G.1
  • 15
    • 0031265017 scopus 로고    scopus 로고
    • Bioactivity of human GM-CSF gene therapy in metastatic renal cell carcinoma and prostate cancer
    • Simons JW. Bioactivity of human GM-CSF gene therapy in metastatic renal cell carcinoma and prostate cancer. Hinyokika Kiyo 1997; 43: 821-822.
    • (1997) Hinyokika Kiyo , vol.43 , pp. 821-822
    • Simons, J.W.1
  • 16
    • 16944364126 scopus 로고    scopus 로고
    • A phase I study of vaccination with autologous, irradiated melanoma cells engineered to secrete human granulocyte-macrophage colony stimulating factor
    • Dranoff G, Soiffer R, Lynch T, Mihm M, Jung K, Kolesar K et al. A phase I study of vaccination with autologous, irradiated melanoma cells engineered to secrete human granulocyte-macrophage colony stimulating factor. Hum Gene Ther 1997; 8: 111-123.
    • (1997) Hum Gene Ther , vol.8 , pp. 111-123
    • Dranoff, G.1    Soiffer, R.2    Lynch, T.3    Mihm, M.4    Jung, K.5    Kolesar, K.6
  • 17
    • 0141576738 scopus 로고    scopus 로고
    • Vaccination with irradiated, autologous melanoma cells engineered to secrete granulocyte-macrophage colony-stimulating factor by adenoviral-mediated gene transfer augments antitumor immunity in patients with metastatic melanoma
    • Soiffer R, Hodi FS, Haluska F, Jung K, Gillessen S, Singer S et al. Vaccination with irradiated, autologous melanoma cells engineered to secrete granulocyte-macrophage colony-stimulating factor by adenoviral-mediated gene transfer augments antitumor immunity in patients with metastatic melanoma. J Clin Oncol 2003; 21: 3343-3350.
    • (2003) J Clin Oncol , vol.21 , pp. 3343-3350
    • Soiffer, R.1    Hodi, F.S.2    Haluska, F.3    Jung, K.4    Gillessen, S.5    Singer, S.6
  • 18
    • 0030950724 scopus 로고    scopus 로고
    • Phase I/IB study of immunization with autologous tumor cells transfected with the GM-CSF gene by particle-mediated transfer in patients with melanoma or sarcoma
    • Mahvi DM, Sondel PM, Yang NS, Albertini MR, Schiller JH, Hank J et al. Phase I/IB study of immunization with autologous tumor cells transfected with the GM-CSF gene by particle-mediated transfer in patients with melanoma or sarcoma. Hum Gene Ther 1997; 8: 875-891.
    • (1997) Hum Gene Ther , vol.8 , pp. 875-891
    • Mahvi, D.M.1    Sondel, P.M.2    Yang, N.S.3    Albertini, M.R.4    Schiller, J.H.5    Hank, J.6
  • 19
    • 10744229445 scopus 로고    scopus 로고
    • Granulocyte-macrophage colony-stimulating factor gene-modified autologous tumor vaccines in non-small-cell lung cancer
    • Nemunaitis J, Sterman D, Jablons D, Smith II JW, Fox B, Maples P et al. Granulocyte-macrophage colony-stimulating factor gene-modified autologous tumor vaccines in non-small-cell lung cancer. J Nat Cancer Inst 2004; 96: 326-331.
    • (2004) J Nat Cancer Inst , vol.96 , pp. 326-331
    • Nemunaitis, J.1    Sterman, D.2    Jablons, D.3    Smith II, J.W.4    Fox, B.5    Maples, P.6
  • 21
    • 0033770967 scopus 로고    scopus 로고
    • The genetic approach to the Epstein-Barr virus: From basic virology to gene therapy
    • Delecluse HJ, Hammerschmidt W. The genetic approach to the Epstein-Barr virus: From basic virology to gene therapy. Mol Pathol 2000; 53: 270-279.
    • (2000) Mol Pathol , vol.53 , pp. 270-279
    • Delecluse, H.J.1    Hammerschmidt, W.2
  • 22
    • 0000942112 scopus 로고    scopus 로고
    • Epstein-Barr virus and its replication
    • Knipe DM et al. (eds.), Philadelphia: Lippincott-Williams & Wilkins
    • Kieff E, Rickinson AB. Epstein-Barr virus and its replication. In: Knipe DM et al. (eds.), Field's Virology. Philadelphia: Lippincott-Williams & Wilkins, 2001, pp. 2511-2573.
    • (2001) Field's Virology , pp. 2511-2573
    • Kieff, E.1    Rickinson, A.B.2
  • 23
    • 0032536860 scopus 로고    scopus 로고
    • Epstein-Barr virus-mediated B-cell proliferation is dependent upon latent membrane protein 1, which simulates an activated CD40 receptor
    • Kilger E, Kieser A, Baumann M, Hammerschmidt W. Epstein-Barr virus-mediated B-cell proliferation is dependent upon latent membrane protein 1, which simulates an activated CD40 receptor. EMBO J 1998; 17: 1700-1709.
    • (1998) EMBO J , vol.17 , pp. 1700-1709
    • Kilger, E.1    Kieser, A.2    Baumann, M.3    Hammerschmidt, W.4
  • 24
    • 20144374689 scopus 로고    scopus 로고
    • Latent membrane protein 1 of Epstein-Barr virus coordinately regulates proliferation with control of apoptosis
    • Dirmeier U, Hoffmann R, Kilger E, Schultheiss U, Briseño C, Gires O et al. Latent membrane protein 1 of Epstein-Barr virus coordinately regulates proliferation with control of apoptosis. Oncogene 2005; 24: 1711-1717.
    • (2005) Oncogene , vol.24 , pp. 1711-1717
    • Dirmeier, U.1    Hoffmann, R.2    Kilger, E.3    Schultheiss, U.4    Briseño, C.5    Gires, O.6
  • 26
    • 0025325578 scopus 로고
    • Expression of the BNLF-1 oncogene of Epstein-Barr virus in the skin of transgenic mice induces hyperplasia and aberrant expression of keratin 6
    • Wilson JB, Weinberg W, Johnson R, Yuspa S, Levine AJ. Expression of the BNLF-1 oncogene of Epstein-Barr virus in the skin of transgenic mice induces hyperplasia and aberrant expression of keratin 6. Cell 1990; 61: 1315-1327.
    • (1990) Cell , vol.61 , pp. 1315-1327
    • Wilson, J.B.1    Weinberg, W.2    Johnson, R.3    Yuspa, S.4    Levine, A.J.5
  • 27
    • 0022309824 scopus 로고
    • An EBV membrane protein expressed in immortalized lymphocytes transforms established rodent cells
    • Wang D, Liebowitz D, Kieff E. An EBV membrane protein expressed in immortalized lymphocytes transforms established rodent cells. Cell 1985; 43: 831-840.
    • (1985) Cell , vol.43 , pp. 831-840
    • Wang, D.1    Liebowitz, D.2    Kieff, E.3
  • 28
    • 0024317091 scopus 로고
    • Epstein-Barr virus nuclear protein 2 is a key determinant of lymphocyte transformation
    • Cohen JI, Wang F, Mannick J, Kieff E. Epstein-Barr virus nuclear protein 2 is a key determinant of lymphocyte transformation. Proc Natl Acad Sci USA 1989; 86: 9558-9562.
    • (1989) Proc Natl Acad Sci USA , vol.86 , pp. 9558-9562
    • Cohen, J.I.1    Wang, F.2    Mannick, J.3    Kieff, E.4
  • 29
    • 0025193047 scopus 로고
    • The proteins encoded by the VpreB and lambda 5 pre-B cell-specific genes can associate with each other and with mu heavy chain
    • Karasuyama H, Kudo A, Melchers F. The proteins encoded by the VpreB and lambda 5 pre-B cell-specific genes can associate with each other and with mu heavy chain. J Exp Med 1990; 172: 969-972.
    • (1990) J Exp Med , vol.172 , pp. 969-972
    • Karasuyama, H.1    Kudo, A.2    Melchers, F.3
  • 30
    • 0037069336 scopus 로고    scopus 로고
    • Glycoprotein gp110 of Epstein-Barr virus determines viral tropism and efficiency of infection
    • Neuhierl B, Feederle R, Delecluse HJ. Glycoprotein gp110 of Epstein-Barr virus determines viral tropism and efficiency of infection. Proc Natl Acad Sci USA 2002; 99: 15036-15041.
    • (2002) Proc Natl Acad Sci USA , vol.99 , pp. 15036-15041
    • Neuhierl, B.1    Feederle, R.2    Delecluse, H.J.3
  • 31
    • 0017659644 scopus 로고
    • Clonal transformation of adult human leukocytes by Epstein-Barr virus
    • Sugden B, Mark W. Clonal transformation of adult human leukocytes by Epstein-Barr virus. J Virol 1977; 23: 503-508.
    • (1977) J Virol , vol.23 , pp. 503-508
    • Sugden, B.1    Mark, W.2
  • 32
    • 0026561901 scopus 로고
    • Brefeldin A: Insights into the control of membrane traffic and organelle structure
    • Klausner RD, Donaldson JG, Lippincott-Schwartz J. Brefeldin A: Insights into the control of membrane traffic and organelle structure. J Cell Biol 1992; 116: 1071-1080.
    • (1992) J Cell Biol , vol.116 , pp. 1071-1080
    • Klausner, R.D.1    Donaldson, J.G.2    Lippincott-Schwartz, J.3
  • 33
    • 0025726282 scopus 로고
    • An Epstein-Barr virus-producer line Akata: Establishment of the cell line and analysis of viral DNA
    • Takada K, Horinouchi K, Ono Y, Aya T, Osato T, Takahashi M et al. An Epstein-Barr virus-producer line Akata: Establishment of the cell line and analysis of viral DNA. Virus Genes 1991; 5: 147-156.
    • (1991) Virus Genes , vol.5 , pp. 147-156
    • Takada, K.1    Horinouchi, K.2    Ono, Y.3    Aya, T.4    Osato, T.5    Takahashi, M.6
  • 34
    • 0025657466 scopus 로고
    • Susceptibility to HIV-1 infection of a human B-lymphoblastoid cell line, DG75, transfected with subgenomic DNA fragments of Epstein-Barr virus
    • Goldblum N, Daefler S, Llana T, Ablashi D, Josephs S, Salahuddin Z. Susceptibility to HIV-1 infection of a human B-lymphoblastoid cell line, DG75, transfected with subgenomic DNA fragments of Epstein-Barr virus. Dev Biol Stand 1990; 72: 309-313.
    • (1990) Dev Biol Stand , vol.72 , pp. 309-313
    • Goldblum, N.1    Daefler, S.2    Llana, T.3    Ablashi, D.4    Josephs, S.5    Salahuddin, Z.6
  • 35
    • 0024318485 scopus 로고
    • Establishment and characterization of a unique human cell line that proliferates dependently on GM-CSF, IL-3, or erythropoietin
    • Kitamura T, Tange T, Terasawa T, Chiba S, Kuwaki T, Miyagawa K et al. Establishment and characterization of a unique human cell line that proliferates dependently on GM-CSF, IL-3, or erythropoietin. J Cell Physiol 1989; 140: 323-334.
    • (1989) J Cell Physiol , vol.140 , pp. 323-334
    • Kitamura, T.1    Tange, T.2    Terasawa, T.3    Chiba, S.4    Kuwaki, T.5    Miyagawa, K.6
  • 36
    • 0346752117 scopus 로고    scopus 로고
    • Efficient generation and expansion of antigen-specific CD4+ T cells by recombinant influenza viruses
    • Nimmerjahn F, Kobelt D, Steinkasserer A, Menke A, Hobom G, Behrends U et al. Efficient generation and expansion of antigen-specific CD4+ T cells by recombinant influenza viruses. Eur J Immunol 2003; 33: 3331-3341.
    • (2003) Eur J Immunol , vol.33 , pp. 3331-3341
    • Nimmerjahn, F.1    Kobelt, D.2    Steinkasserer, A.3    Menke, A.4    Hobom, G.5    Behrends, U.6
  • 37
    • 0029148878 scopus 로고
    • Dendritic cells use macropinocytosis and the mannose receptor to concentrate macromolecules in the major histocompatibility complex class II compartment: Downregulation by cytokines and bacterial products
    • Sallusto F, Cella M, Danieli C, Lanzavecchia A. Dendritic cells use macropinocytosis and the mannose receptor to concentrate macromolecules in the major histocompatibility complex class II compartment: downregulation by cytokines and bacterial products. J Exp Med 1995; 182: 389-400.
    • (1995) J Exp Med , vol.182 , pp. 389-400
    • Sallusto, F.1    Cella, M.2    Danieli, C.3    Lanzavecchia, A.4
  • 40
    • 0142089747 scopus 로고    scopus 로고
    • Fatal systemic inflammatory response syndrome in a ornithine transcarbamylase deficient patient following adenoviral gene transfer
    • Raper SE, Chirmule N, Lee FS, Wivel NA, Bagg A, Gao GP et al. Fatal systemic inflammatory response syndrome in a ornithine transcarbamylase deficient patient following adenoviral gene transfer. Mol Genet Metab 2003; 80: 148-158.
    • (2003) Mol Genet Metab , vol.80 , pp. 148-158
    • Raper, S.E.1    Chirmule, N.2    Lee, F.S.3    Wivel, N.A.4    Bagg, A.5    Gao, G.P.6
  • 41
    • 0345734204 scopus 로고    scopus 로고
    • Long-term transgene expression in proliferating cells mediated by episomally maintained high-capacity adenovirus vectors
    • Kreppel F, Kochanek S. Long-term transgene expression in proliferating cells mediated by episomally maintained high-capacity adenovirus vectors. J Virol 2004; 78: 9-22.
    • (2004) J Virol , vol.78 , pp. 9-22
    • Kreppel, F.1    Kochanek, S.2
  • 42
    • 1842588049 scopus 로고    scopus 로고
    • The potential of gene transfer into primary B-CLL cells using recombinant virus vectors
    • Wendtner CM, Kofler DM, Mayr C, Bund D, Hallek M. The potential of gene transfer into primary B-CLL cells using recombinant virus vectors. Leuk Lymphoma 2004; 45: 897-904.
    • (2004) Leuk Lymphoma , vol.45 , pp. 897-904
    • Wendtner, C.M.1    Kofler, D.M.2    Mayr, C.3    Bund, D.4    Hallek, M.5
  • 44
    • 0037429007 scopus 로고    scopus 로고
    • Efficiency of onco-retroviral and lentiviral gene transfer into primary mouse and human B-lymphocytes is pseudotype dependent
    • Janssens W, Chuah MK, Naldini L, Follenzi A, Collen D, Saint-Remy JM et al. Efficiency of onco-retroviral and lentiviral gene transfer into primary mouse and human B-lymphocytes is pseudotype dependent. Hum Gene Therapy 2003; 14: 263-276.
    • (2003) Hum Gene Therapy , vol.14 , pp. 263-276
    • Janssens, W.1    Chuah, M.K.2    Naldini, L.3    Follenzi, A.4    Collen, D.5    Saint-Remy, J.M.6
  • 45
    • 1642474100 scopus 로고    scopus 로고
    • Functional transfer of CD40L gene in human B-cell precursor ALL blasts by second-generation SIN lenti-vectors
    • Bonamino M, Serafini M, D'Amico G, Gaipa G, Todisco E, Bernasconi S et al. Functional transfer of CD40L gene in human B-cell precursor ALL blasts by second-generation SIN lenti-vectors. Gene Therapy 2004; 11: 85-93.
    • (2004) Gene Therapy , vol.11 , pp. 85-93
    • Bonamino, M.1    Serafini, M.2    D'Amico, G.3    Gaipa, G.4    Todisco, E.5    Bernasconi, S.6
  • 46
    • 1842636260 scopus 로고    scopus 로고
    • Lentivirus vector-mediated expression of tumor-associated epitopes by human antigen presenting cells
    • Lizee G, Gonzales MI, Topalian SL. Lentivirus vector-mediated expression of tumor-associated epitopes by human antigen presenting cells. Hum Gene Therapy 2004; 15: 393-404.
    • (2004) Hum Gene Therapy , vol.15 , pp. 393-404
    • Lizee, G.1    Gonzales, M.I.2    Topalian, S.L.3
  • 47
    • 0032990331 scopus 로고    scopus 로고
    • Control of cell cycle entry and apoptosis in B lymphocytes infected by Epstein-Barr virus
    • Spender LC, Cannell EJ, Hollyoake M, Wensing B, Gawn JM, Brimmell M et al. Control of cell cycle entry and apoptosis in B lymphocytes infected by Epstein-Barr virus. J Virol 1999; 73: 4678-4688.
    • (1999) J Virol , vol.73 , pp. 4678-4688
    • Spender, L.C.1    Cannell, E.J.2    Hollyoake, M.3    Wensing, B.4    Gawn, J.M.5    Brimmell, M.6
  • 48
    • 11144255665 scopus 로고    scopus 로고
    • Gene therapy progress and prospects: Episomally maintained self-replicating systems
    • Conese M, Auriche C, Ascenzioni F. Gene therapy progress and prospects: episomally maintained self-replicating systems. Gene Therapy 2004; 11: 1735-1741.
    • (2004) Gene Therapy , vol.11 , pp. 1735-1741
    • Conese, M.1    Auriche, C.2    Ascenzioni, F.3
  • 49
    • 0032573225 scopus 로고    scopus 로고
    • Vaccination with irradiated autologous melanoma cells engineered to secrete human granulocyte-macrophage colony-stimulating factor generates potent antitumor immunity in patients with metastatic melanoma
    • Soiffer R, Lynch T, Mihm M, Jung K, Rhuda C, Schmollinger JC et al. Vaccination with irradiated autologous melanoma cells engineered to secrete human granulocyte-macrophage colony-stimulating factor generates potent antitumor immunity in patients with metastatic melanoma. Proc Natl Acad Sci USA 1998; 95: 13141-13146.
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 13141-13146
    • Soiffer, R.1    Lynch, T.2    Mihm, M.3    Jung, K.4    Rhuda, C.5    Schmollinger, J.C.6
  • 51
    • 6544295248 scopus 로고    scopus 로고
    • Induction of tumor immunity by autologous B lymphoma cells expressing a genetically engineered idiotype
    • Selmayr M et al. Induction of tumor immunity by autologous B lymphoma cells expressing a genetically engineered idiotype. Gene Therapy 1999; 6: 778-784.
    • (1999) Gene Therapy , vol.6 , pp. 778-784
    • Selmayr, M.1
  • 52
    • 0033821972 scopus 로고    scopus 로고
    • Cytokine-secreting tumor cell vaccines
    • Mach N, Dranoff G. Cytokine-secreting tumor cell vaccines. Curr Opin Immunol 2000; 12: 571-575.
    • (2000) Curr Opin Immunol , vol.12 , pp. 571-575
    • Mach, N.1    Dranoff, G.2
  • 53
    • 0029963944 scopus 로고    scopus 로고
    • Immunization with granulocyte-macrophage colony-stimulating factor-transduced, but not B7-1-transduced, lymphoma cells primes idiotype-specific T cells and generates potent systemic antitumor immunity
    • Levitsky HI et al. Immunization with granulocyte-macrophage colony-stimulating factor-transduced, but not B7-1-transduced, lymphoma cells primes idiotype-specific T cells and generates potent systemic antitumor immunity. J Immunol 1996; 156: 3858-3865.
    • (1996) J Immunol , vol.156 , pp. 3858-3865
    • Levitsky, H.I.1
  • 54
    • 0035731401 scopus 로고    scopus 로고
    • Epstein-Barr virus can infect B-chronic lymphocytic leukemia cells but it does not orchestrate the cell cycle regulatory proteins
    • Maeda A et al. Epstein-Barr virus can infect B-chronic lymphocytic leukemia cells but it does not orchestrate the cell cycle regulatory proteins. J Hum Virol 2001; 4: 227-237.
    • (2001) J Hum Virol , vol.4 , pp. 227-237
    • Maeda, A.1
  • 55
    • 0033943249 scopus 로고    scopus 로고
    • Epstein-Barr virus-infected B-chronic lymphocyte leukemia cells express the virally encoded nuclear proteins but they do not enter the cell cycle
    • Teramoto N et al. Epstein-Barr virus-infected B-chronic lymphocyte leukemia cells express the virally encoded nuclear proteins but they do not enter the cell cycle. J Hum Virol 2000; 3: 125-136.
    • (2000) J Hum Virol , vol.3 , pp. 125-136
    • Teramoto, N.1
  • 56
    • 0141455122 scopus 로고    scopus 로고
    • Vaccination against B-cell chronic lymphocytic leukemia with trioma cells: Preclinical evaluation
    • Wahl U et al. Vaccination against B-cell chronic lymphocytic leukemia with trioma cells: Preclinical evaluation. Clin Cancer Res 2003; 9: 4240-4246.
    • (2003) Clin Cancer Res , vol.9 , pp. 4240-4246
    • Wahl, U.1
  • 57
    • 0030860064 scopus 로고    scopus 로고
    • Versatile insertion plasmids for targeted genome manipulations in bacteria: Isolation, deletion, and rescue of the pathogenicity island LEE of the Escherichia coli O157:H7 genome
    • Posfai G, Koob MD, Kirkpatrick HA, Blattner FR. Versatile insertion plasmids for targeted genome manipulations in bacteria: Isolation, deletion, and rescue of the pathogenicity island LEE of the Escherichia coli O157:H7 genome. J Bacteriol 1997; 179: 4426-4428.
    • (1997) J Bacteriol , vol.179 , pp. 4426-4428
    • Posfai, G.1    Koob, M.D.2    Kirkpatrick, H.A.3    Blattner, F.R.4
  • 58
    • 0024390820 scopus 로고
    • Construction of large DNA segments in Escherichia coli
    • O'Connor M, Peifer M, Bender W. Construction of large DNA segments in Escherichia coli. Science 1989; 244: 1307-1312.
    • (1989) Science , vol.244 , pp. 1307-1312
    • O'Connor, M.1    Peifer, M.2    Bender, W.3
  • 59
    • 0029065955 scopus 로고
    • Gene disruption in Escherichia coli: TcR and KmR cassettes with the option of Flp-catalyzed excision of the antibiotic-resistance determinant
    • Cherepanov PP,Wackernagel W. Gene disruption in Escherichia coli: TcR and KmR cassettes with the option of Flp-catalyzed excision of the antibiotic-resistance determinant. Gene 1995; 158: 9-14.
    • (1995) Gene , vol.158 , pp. 9-14
    • Cherepanov, P.P.1    Wackernagel, W.2
  • 60
    • 0023698910 scopus 로고
    • Identification and characterization of oriLyt, a lytic origin of DNA replication of Epstein-Barr virus
    • Hammerschmidt W, Sugden B. Identification and characterization of oriLyt, a lytic origin of DNA replication of Epstein-Barr virus. Cell 1988; 55: 427-433.
    • (1988) Cell , vol.55 , pp. 427-433
    • Hammerschmidt, W.1    Sugden, B.2
  • 61
    • 0035887040 scopus 로고    scopus 로고
    • TRAF6 is a critical mediator of signal transduction by the viral oncogene latent membrane protein 1
    • Schultheiss U et al. TRAF6 is a critical mediator of signal transduction by the viral oncogene latent membrane protein 1. EMBO J 2001; 20: 5678-5691.
    • (2001) EMBO J , vol.20 , pp. 5678-5691
    • Schultheiss, U.1
  • 62
    • 0037960005 scopus 로고    scopus 로고
    • Major histocompatibility complex class II-restricted presentation of a cytosolic antigen by autophagy
    • Nimmerjahn F et al. Major histocompatibility complex class II-restricted presentation of a cytosolic antigen by autophagy. Eur J Immunol 2003; 33: 1250-1259.
    • (2003) Eur J Immunol , vol.33 , pp. 1250-1259
    • Nimmerjahn, F.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.