Double suicide gene therapy using a replication defective herpes simplex virus vector reveals reciprocal interference in a malignant glioma model

Gene Therapy

Volumn 9, Issue 9, 2002, Pages 584-591

  Moriuchi, S ^a   Wolfe, D ^a   Tamura, M ^a   Yoshimine, T ^b   Miura, F ^b   Cohen, J B ^a   Glorioso, J C ^a  

^a UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^b OSAKA UNIVERSITY MEDICAL SCHOOL   (Japan)

Author keywords

Cytosine deaminase; Gene therapy; Glioma; Herpes simplex virus; HSV thymidine kinase

Indexed keywords

CYTOSINE DEAMINASE; DRUG METABOLITE; FLUCYTOSINE; GANCICLOVIR; PRODRUG; THYMIDINE KINASE; VIRUS VECTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CANCER SURVIVAL; CONTROLLED STUDY; CYTOTOXICITY; DEFECTIVE VIRUS; ESCHERICHIA COLI; FEMALE; GENE EXPRESSION; GLIOBLASTOMA; GLIOMA CELL; GLIOSARCOMA; HERPES SIMPLEX VIRUS; IN VITRO STUDY; IN VIVO STUDY; NONHUMAN; PRIORITY JOURNAL; RAT; SUICIDE GENE THERAPY; TUMOR CELL CULTURE; VIRUS INTERFERENCE; VIRUS REPLICATION;

ANIMALS; ANTIVIRAL AGENTS; CYTOSINE DEAMINASE; ESCHERICHIA COLI; FEMALE; FLUCYTOSINE; GANCICLOVIR; GENE THERAPY; GENETIC VECTORS; GLIOMA; MODELS, ANIMAL; NUCLEOSIDE DEAMINASES; RATS; RATS, INBRED F344; SIMPLEXVIRUS; THYMIDINE KINASE; TUMOR CELLS, CULTURED;

ANIMALIA; ESCHERICHIA COLI; MAMMALIA; SIMPLEXVIRUS;

EID: 0036262606     PISSN: 09697128     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.gt.3301693     Document Type: Article

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