Analysis of lentiviral vector integration in HIV+ study subjects receiving autologous infusions of gene modified CD4+ T cells

Molecular Therapy

Volumn 17, Issue 5, 2009, Pages 844-850

  Wang, Gary P ^a   Levine, Bruce L ^a   Binder, Gwendolyn K ^a   Berry, Charles C ^b   Malani, Nirav ^a   McGarrity, Gary ^c   Tebas, Pablo ^a   June, Carl H ^a   Bushman, Frederic D ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c VIRxSYS Corporation   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

LENTIVIRUS VECTOR;

ARTICLE; CASE REPORT; CD4+ T LYMPHOCYTE; CELL EXPANSION; CONTROLLED STUDY; DNA MODIFICATION; EPIGENETICS; EX VIVO STUDY; GENE ACTIVATION; GENE TARGETING; GENETIC TRANSCRIPTION; GENETIC TRANSDUCTION; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; LYMPHOCYTE TRANSFER; NUCLEOSOME; PERIPHERAL BLOOD MONONUCLEAR CELL; PROTO ONCOGENE; PYROSEQUENCING; TUMOR SUPPRESSOR GENE; VIRUS DNA CELL DNA INTERACTION;

CD4-POSITIVE T-LYMPHOCYTES; CLINICAL TRIALS, PHASE I AS TOPIC; CLINICAL TRIALS, PHASE II AS TOPIC; COMPUTATIONAL BIOLOGY; GENETIC VECTORS; HIV INFECTIONS; HUMANS; LENTIVIRUS; SEQUENCE ANALYSIS, DNA; VIRUS INTEGRATION;

HUMAN IMMUNODEFICIENCY VIRUS;

EID: 67349132909     PISSN: 15250016     EISSN: 15250024     Source Type: Journal    
DOI: 10.1038/mt.2009.16     Document Type: Article

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