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Volumn 18, Issue 1, 2011, Pages 42-52

Enhanced tumor therapy using vaccinia virus strain GLV-1h68 in combination with a Β-galactosidase-activatable prodrug seco-analog of duocarmycin SA

Author keywords

breast cancer; oncolytic virotherapy; prodrug; vaccinia virus

Indexed keywords

BETA GALACTOSIDASE; DUOCARMYCIN SA;

EID: 78650309660     PISSN: 09291903     EISSN: 14765500     Source Type: Journal    
DOI: 10.1038/cgt.2010.49     Document Type: Article
Times cited : (29)

References (45)
  • 2
    • 67650385302 scopus 로고    scopus 로고
    • American Cancer Society
    • American Cancer Society. Cancer facts and figures 2009. 2009. http://www.cancer.org.
    • (2009) Cancer Facts and Figures 2009
  • 3
    • 49249131785 scopus 로고    scopus 로고
    • Virus combinations and chemotherapy for the treatment of human cancers
    • Kumar S, Gao L, Yeagy B, Reid T. Virus combinations and chemotherapy for the treatment of human cancers. Curr Opin Mol Ther 2008; 10: 371-379.
    • (2008) Curr Opin Mol Ther , vol.10 , pp. 371-379
    • Kumar, S.1    Gao, L.2    Yeagy, B.3    Reid, T.4
  • 5
    • 0029976870 scopus 로고    scopus 로고
    • Genetically engineered poxviruses for recombinant gene expression, vaccination, and safety
    • Moss B. Genetically engineered poxviruses for recombinant gene expression, vaccination, and safety. Proc Natl Acad Sci USA 1996; 93: 11341-11348.
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 11341-11348
    • Moss, B.1
  • 6
    • 0033950819 scopus 로고    scopus 로고
    • Vaccinia as a vector for tumor-directed gene therapy: Biodistribution of a thymidine kinase-deleted mutant
    • Puhlmann M, Brown CK, Gnant M, Huang J, Libutti SK, Alexander HR et al. Vaccinia as a vector for tumor-directed gene therapy: biodistribution of a thymidine kinase-deleted mutant. Cancer Gene Ther 2000; 7: 66-73.
    • (2000) Cancer Gene Ther , vol.7 , pp. 66-73
    • Puhlmann, M.1    Brown, C.K.2    Gnant, M.3    Huang, J.4    Libutti, S.K.5    Alexander, H.R.6
  • 7
    • 35448962430 scopus 로고    scopus 로고
    • Eradication of solid human breast tumors in nude mice with an intravenously injected light-emitting oncolytic vaccinia virus
    • Zhang Q, Yu YA, Wang E, Chen N, Danner RL, Munson PJ et al. Eradication of solid human breast tumors in nude mice with an intravenously injected light-emitting oncolytic vaccinia virus. Cancer Res 2007; 67: 10038-10046.
    • (2007) Cancer Res , vol.67 , pp. 10038-10046
    • Zhang, Q.1    Yu, Y.A.2    Wang, E.3    Chen, N.4    Danner, R.L.5    Munson, P.J.6
  • 8
    • 1542336958 scopus 로고    scopus 로고
    • Visualization of tumors and metastases in live animals with bacteria and vaccinia virus encoding light-emitting proteins
    • Yu YA, Shabahang S, Timiryasova TM, Zhang Q, Beltz R, Gentschev I et al. Visualization of tumors and metastases in live animals with bacteria and vaccinia virus encoding light-emitting proteins. Nat Biotechnol 2004; 22: 313-320.
    • (2004) Nat Biotechnol , vol.22 , pp. 313-320
    • Yu, Y.A.1    Shabahang, S.2    Timiryasova, T.M.3    Zhang, Q.4    Beltz, R.5    Gentschev, I.6
  • 9
    • 33845409424 scopus 로고    scopus 로고
    • Viral vectors for gene-directed enzyme prodrug therapy
    • Schepelmann S, Springer CJ. Viral vectors for gene-directed enzyme prodrug therapy. Curr Gene Ther 2006; 6: 647-670.
    • (2006) Curr Gene Ther , vol.6 , pp. 647-670
    • Schepelmann, S.1    Springer, C.J.2
  • 10
    • 38349079989 scopus 로고    scopus 로고
    • Oncolytic virotherapy for ovarian carcinomatosis using a replication-selective vaccinia virus armed with a yeast cytosine deaminase gene
    • Chalikonda S, Kivlen MH, O'Malley ME, Eric Dong XD, McCart JA, Gorry MC et al. Oncolytic virotherapy for ovarian carcinomatosis using a replication-selective vaccinia virus armed with a yeast cytosine deaminase gene. Cancer Gene Ther 2008; 15: 115-125.
    • (2008) Cancer Gene Ther , vol.15 , pp. 115-125
    • Chalikonda, S.1    Kivlen, M.H.2    O'Malley, M.E.3    Eric Dong, X.D.4    McCart, J.A.5    Gorry, M.C.6
  • 12
    • 53649094575 scopus 로고    scopus 로고
    • Targeted delivery of a suicide gene to human colorectal tumors by a conditionally replicating vaccinia virus
    • Foloppe J, Kintz J, Futin N, Findeli A, Cordier P, Schlesinger Y et al. Targeted delivery of a suicide gene to human colorectal tumors by a conditionally replicating vaccinia virus. Gene Ther 2008; 15: 1361-1371.
    • (2008) Gene Ther , vol.15 , pp. 1361-1371
    • Foloppe, J.1    Kintz, J.2    Futin, N.3    Findeli, A.4    Cordier, P.5    Schlesinger, Y.6
  • 13
    • 0033565215 scopus 로고    scopus 로고
    • Systemic administration of a recombinant vaccinia virus expressing the cytosine deaminase gene and subsequent treatment with 5-fluorocytosine leads to tumor-specific gene expression and prolongation of survival in mice
    • Gnant MF, Puhlmann M, Alexander Jr HR, Bartlett DL. Systemic administration of a recombinant vaccinia virus expressing the cytosine deaminase gene and subsequent treatment with 5-fluorocytosine leads to tumor-specific gene expression and prolongation of survival in mice. Cancer Res 1999; 59: 3396-3403.
    • (1999) Cancer Res , vol.59 , pp. 3396-3403
    • Gnant, M.F.1    Puhlmann, M.2    Alexander Jr., H.R.3    Bartlett, D.L.4
  • 14
    • 0033929022 scopus 로고    scopus 로고
    • Complex interactions between the replicating oncolytic effect and the enzyme/prodrug effect of vaccinia-mediated tumor regression
    • McCart JA, Puhlmann M, Lee J, Hu Y, Libutti SK, Alexander HR et al. Complex interactions between the replicating oncolytic effect and the enzyme/prodrug effect of vaccinia-mediated tumor regression. Gene Ther 2000; 7: 1217-1223.
    • (2000) Gene Ther , vol.7 , pp. 1217-1223
    • McCart, J.A.1    Puhlmann, M.2    Lee, J.3    Hu, Y.4    Libutti, S.K.5    Alexander, H.R.6
  • 15
    • 17344371681 scopus 로고    scopus 로고
    • Beta-galactosidase gene transfer to human malignant glioma in vivo using replication-deficient retroviruses and adenoviruses
    • Puumalainen AM, Vapalahti M, Agrawal RS, Kossila M, Laukkanen J, Lehtolainen P et al. Beta-galactosidase gene transfer to human malignant glioma in vivo using replication-deficient retroviruses and adenoviruses. Hum Gene Ther 1998; 9: 1769-1774.
    • (1998) Hum Gene Ther , vol.9 , pp. 1769-1774
    • Puumalainen, A.M.1    Vapalahti, M.2    Agrawal, R.S.3    Kossila, M.4    Laukkanen, J.5    Lehtolainen, P.6
  • 16
  • 18
    • 35848962532 scopus 로고    scopus 로고
    • Non-invasive in vivo optical imaging of the lacZ and luc gene expression in mice
    • Josserand V, Texier-Nogues I, Huber P, Favrot MC, Coll JL. Non-invasive in vivo optical imaging of the lacZ and luc gene expression in mice. Gene Ther 2007; 14: 1587-1593.
    • (2007) Gene Ther , vol.14 , pp. 1587-1593
    • Josserand, V.1    Texier-Nogues, I.2    Huber, P.3    Favrot, M.C.4    Coll, J.L.5
  • 19
    • 33645278110 scopus 로고    scopus 로고
    • Luminescent imaging of beta-galactosidase activity in living subjects using sequential reporter-enzyme luminescence
    • Wehrman TS, von Degenfeld G, Krutzik PO, Nolan GP, Blau HM. Luminescent imaging of beta-galactosidase activity in living subjects using sequential reporter-enzyme luminescence. Nat Methods 2006; 3: 295-301.
    • (2006) Nat Methods , vol.3 , pp. 295-301
    • Wehrman, T.S.1    Von Degenfeld, G.2    Krutzik, P.O.3    Nolan, G.P.4    Blau, H.M.5
  • 20
    • 1542318455 scopus 로고    scopus 로고
    • Targeting of lacZ reporter gene expression with radioiodine-labelled phenylethyl-beta-d-thiogalactopyranoside
    • Lee KH, Byun SS, Choi JH, Paik JY, Choe YS, Kim BT. Targeting of lacZ reporter gene expression with radioiodine-labelled phenylethyl-beta-d- thiogalactopyranoside. Eur J Nucl Med Mol Imaging 2004; 31: 433-438.
    • (2004) Eur J Nucl Med Mol Imaging , vol.31 , pp. 433-438
    • Lee, K.H.1    Byun, S.S.2    Choi, J.H.3    Paik, J.Y.4    Choe, Y.S.5    Kim, B.T.6
  • 22
    • 65549140215 scopus 로고    scopus 로고
    • Novel analogues of CC-1065 and the duocarmycins for the use in targeted tumour therapies
    • Tietze LF, Krewer B. Novel analogues of CC-1065 and the duocarmycins for the use in targeted tumour therapies. Anticancer Agents Med Chem 2009; 9: 304-325.
    • (2009) Anticancer Agents Med Chem , vol.9 , pp. 304-325
    • Tietze, L.F.1    Krewer, B.2
  • 23
    • 57549108328 scopus 로고    scopus 로고
    • Asymmetric synthesis and biological evaluation of glycosidic prodrugs for a selective cancer therapy
    • Tietze LF, von Hof JM, Krewer B, Muller M, Major F, Schuster HJ et al. Asymmetric synthesis and biological evaluation of glycosidic prodrugs for a selective cancer therapy. ChemMedChem 2008; 3: 1946-1955.
    • (2008) ChemMedChem , vol.3 , pp. 1946-1955
    • Tietze, L.F.1    Von Hof, J.M.2    Krewer, B.3    Muller, M.4    Major, F.5    Schuster, H.J.6
  • 24
    • 34247618171 scopus 로고    scopus 로고
    • Tumor-specific colonization, tissue distribution, and gene induction by probiotic Escherichia coli Nissle 1917 in live mice
    • Stritzker J, Weibel S, Hill PJ, Oelschlaeger TA, Goebel W, Szalay AA. Tumor-specific colonization, tissue distribution, and gene induction by probiotic Escherichia coli Nissle 1917 in live mice. Int J Med Microbiol 2007; 297: 151-162.
    • (2007) Int J Med Microbiol , vol.297 , pp. 151-162
    • Stritzker, J.1    Weibel, S.2    Hill, P.J.3    Oelschlaeger, T.A.4    Goebel, W.5    Szalay, A.A.6
  • 25
    • 34147186268 scopus 로고    scopus 로고
    • Distamycin A enhances the cytotoxicity of duocarmycin A and suppresses duocarmycin A-induced apoptosis in human lung carcinoma cells
    • Hirota M, Fujiwara T, Mineshita S, Sugiyama H, Teraoka H. Distamycin A enhances the cytotoxicity of duocarmycin A and suppresses duocarmycin A-induced apoptosis in human lung carcinoma cells. Int J Biochem Cell Biol 2007; 39: 988-996.
    • (2007) Int J Biochem Cell Biol , vol.39 , pp. 988-996
    • Hirota, M.1    Fujiwara, T.2    Mineshita, S.3    Sugiyama, H.4    Teraoka, H.5
  • 26
    • 0032924009 scopus 로고    scopus 로고
    • Generation of hydrogen peroxide precedes loss of mitochondrial membrane potential during DNA alkyla-tion-induced apoptosis
    • Tada-Oikawa S, Oikawa S, Kawanishi M, Yamada M, Kawanishi S. Generation of hydrogen peroxide precedes loss of mitochondrial membrane potential during DNA alkyla-tion-induced apoptosis. FEBS Lett 1999; 442: 65-69.
    • (1999) FEBS Lett , vol.442 , pp. 65-69
    • Tada-Oikawa, S.1    Oikawa, S.2    Kawanishi, M.3    Yamada, M.4    Kawanishi, S.5
  • 27
    • 0028219281 scopus 로고
    • Induction of endonucleolytic DNA fragmentation and apoptosis by the duocarmycins
    • Wrasidlo W, Johnson DS, Boger DL. Induction of endonucleolytic DNA fragmentation and apoptosis by the duocarmycins. Bioorg Med Chem Lett 1994; 4: 631-636.
    • (1994) Bioorg Med Chem Lett , vol.4 , pp. 631-636
    • Wrasidlo, W.1    Johnson, D.S.2    Boger, D.L.3
  • 28
  • 29
    • 1542357606 scopus 로고    scopus 로고
    • Apoptosis pathways in cancer and cancer therapy
    • Debatin KM. Apoptosis pathways in cancer and cancer therapy. Cancer Immunol Immunother 2004; 53: 153-159.
    • (2004) Cancer Immunol Immunother , vol.53 , pp. 153-159
    • Debatin, K.M.1
  • 30
    • 16844377506 scopus 로고    scopus 로고
    • Recent advances in understanding the cell death pathways activated by anticancer therapy
    • Kim R. Recent advances in understanding the cell death pathways activated by anticancer therapy. Cancer 2005; 103: 1551-1560.
    • (2005) Cancer , vol.103 , pp. 1551-1560
    • Kim, R.1
  • 31
    • 29144495592 scopus 로고    scopus 로고
    • Near death experiences: Poxvirus regulation of apoptotic death
    • Taylor JM, Barry M. Near death experiences: poxvirus regulation of apoptotic death. Virology 2006; 344: 139-150.
    • (2006) Virology , vol.344 , pp. 139-150
    • Taylor, J.M.1    Barry, M.2
  • 33
    • 0032585793 scopus 로고    scopus 로고
    • Expression of mdm-2 oncoprotein in the primary and metastatic sites of mammary tumor (GI-101) implanted athymic nude mice
    • Rathinavelu P, Malave A, Raney SR, Hurst J, Roberson CT, Rathinavelu A. Expression of mdm-2 oncoprotein in the primary and metastatic sites of mammary tumor (GI-101) implanted athymic nude mice. Cancer Biochem Biophys 1999; 17: 133-146.
    • (1999) Cancer Biochem Biophys , vol.17 , pp. 133-146
    • Rathinavelu, P.1    Malave, A.2    Raney, S.R.3    Hurst, J.4    Roberson, C.T.5    Rathinavelu, A.6
  • 34
    • 62549116964 scopus 로고    scopus 로고
    • Use of an oncolytic vaccinia virus for the treatment of canine breast cancer in nude mice: Preclinical development of a therapeutic agent
    • Gentschev I, Stritzker J, Hofmann E, Weibel S, Yu YA, Chen N et al. Use of an oncolytic vaccinia virus for the treatment of canine breast cancer in nude mice: preclinical development of a therapeutic agent. Cancer Gene Ther 2009; 16: 320-328.
    • (2009) Cancer Gene Ther , vol.16 , pp. 320-328
    • Gentschev, I.1    Stritzker, J.2    Hofmann, E.3    Weibel, S.4    Yu, Y.A.5    Chen, N.6
  • 35
    • 0028376605 scopus 로고
    • Molecular basis for sequence selective DNA alkylation by (+)- and ent-(-)-CC-1065 and related agents: Alkylation site models that accommodate the offset AT-rich adenine N3 alkylation selectivity
    • Boger DL, Johnson DS, Yun W, Tarby CM. Molecular basis for sequence selective DNA alkylation by (+)- and ent-(-)-CC-1065 and related agents: alkylation site models that accommodate the offset AT-rich adenine N3 alkylation selectivity. Bioorg Med Chem 1994; 2: 115-135.
    • (1994) Bioorg Med Chem , vol.2 , pp. 115-135
    • Boger, D.L.1    Johnson, D.S.2    Yun, W.3    Tarby, C.M.4
  • 36
    • 33845972661 scopus 로고    scopus 로고
    • The vaccinia virus protein F1 L interacts with Bim and inhibits activation of the pro-apoptotic protein Bax
    • Taylor JM, Quilty D, Banadyga L, Barry M. The vaccinia virus protein F1 L interacts with Bim and inhibits activation of the pro-apoptotic protein Bax. J Biol Chem 2006; 281: 39728-39739.
    • (2006) J Biol Chem , vol.281 , pp. 39728-39739
    • Taylor, J.M.1    Quilty, D.2    Banadyga, L.3    Barry, M.4
  • 37
    • 11144245597 scopus 로고    scopus 로고
    • Vaccinia virus F1L protein is a tail-anchored protein that functions at the mitochondria to inhibit apoptosis
    • Stewart TL, Wasilenko ST, Barry M. Vaccinia virus F1L protein is a tail-anchored protein that functions at the mitochondria to inhibit apoptosis. J Virol 2005; 79: 1084-1098.
    • (2005) J Virol , vol.79 , pp. 1084-1098
    • Stewart, T.L.1    Wasilenko, S.T.2    Barry, M.3
  • 38
    • 27644535708 scopus 로고    scopus 로고
    • The vaccinia virus F1L protein interacts with the proapoptotic protein Bak and inhibits Bak activation
    • Wasilenko ST, Banadyga L, Bond D, Barry M. The vaccinia virus F1L protein interacts with the proapoptotic protein Bak and inhibits Bak activation. J Virol 2005; 79: 14031-14043.
    • (2005) J Virol , vol.79 , pp. 14031-14043
    • Wasilenko, S.T.1    Banadyga, L.2    Bond, D.3    Barry, M.4
  • 39
    • 0035169626 scopus 로고    scopus 로고
    • Vaccinia virus infection disarms the mitochondrion-mediated pathway of the apoptotic cascade by modulating the permeability transition pore
    • Wasilenko ST, Meyers AF, Vander Helm K, Barry M. Vaccinia virus infection disarms the mitochondrion-mediated pathway of the apoptotic cascade by modulating the permeability transition pore. J Virol 2001; 75: 11437-11448.
    • (2001) J Virol , vol.75 , pp. 11437-11448
    • Wasilenko, S.T.1    Meyers, A.F.2    Vander Helm, K.3    Barry, M.4
  • 40
    • 0344198504 scopus 로고    scopus 로고
    • Vaccinia virus encodes a previously uncharacterized mitochondrial- associated inhibitor of apoptosis
    • Wasilenko ST, Stewart TL, Meyers AF, Barry M. Vaccinia virus encodes a previously uncharacterized mitochondrial-associated inhibitor of apoptosis. Proc Natl Acad Sci USA 2003; 100: 14345-14350.
    • (2003) Proc Natl Acad Sci USA , vol.100 , pp. 14345-14350
    • Wasilenko, S.T.1    Stewart, T.L.2    Meyers, A.F.3    Barry, M.4
  • 41
    • 58149464705 scopus 로고    scopus 로고
    • Real-time intraoperative detection of melanoma lymph node metastases using recombinant vaccinia virus GLV-1h68 in an immunocompetent animal model
    • Kelly KJ, Brader P, Woo Y, Li S, Chen N, Yu YA et al. Real-time intraoperative detection of melanoma lymph node metastases using recombinant vaccinia virus GLV-1h68 in an immunocompetent animal model. Int J Cancer 2009; 124: 911-918.
    • (2009) Int J Cancer , vol.124 , pp. 911-918
    • Kelly, K.J.1    Brader, P.2    Woo, Y.3    Li, S.4    Chen, N.5    Yu, Y.A.6
  • 42
    • 77951675565 scopus 로고    scopus 로고
    • Regression of human prostate tumors and metastases in nude mice following treatment with the recombinant oncolytic vaccinia virus GLV-1h68
    • e-pub ahead of print 23 June 2010; doi:10.1155/2010/736907
    • Gentschev I, Hofmann E, Donat U, Weibel S, Adelfinger M, Raab V et al. Regression of human prostate tumors and metastases in nude mice following treatment with the recombinant oncolytic vaccinia virus GLV-1h68. J Biomed Biotechnol 2010; e-pub ahead of print 23 June 2010; doi:10.1155/2010/736907.
    • J Biomed Biotechnol 2010
    • Gentschev, I.1    Hofmann, E.2    Donat, U.3    Weibel, S.4    Adelfinger, M.5    Raab, V.6
  • 43
    • 67651214114 scopus 로고    scopus 로고
    • Systemic treatment of xenografts with vaccinia virus GLV-1h68 reveals the immunologic facet of oncolytic therapy
    • Worschech A, Chen N, Yu YA, Zhang Q, Pos Z, Weibel S et al. Systemic treatment of xenografts with vaccinia virus GLV-1h68 reveals the immunologic facet of oncolytic therapy. BMC Genomics 2009; 10: 301.
    • (2009) BMC Genomics , vol.10 , pp. 301
    • Worschech, A.1    Chen, N.2    Yu, Y.A.3    Zhang, Q.4    Pos, Z.5    Weibel, S.6
  • 45
    • 42049089735 scopus 로고    scopus 로고
    • Signatures associated with rejection or recurrence in HER-2/neu-positive mammary tumors
    • Worschech A, Kmieciak M, Knutson KL, Bear HD, Szalay AA, Wang E et al. Signatures associated with rejection or recurrence in HER-2/neu-positive mammary tumors. Cancer Res 2008; 68: 2436-2446.
    • (2008) Cancer Res , vol.68 , pp. 2436-2446
    • Worschech, A.1    Kmieciak, M.2    Knutson, K.L.3    Bear, H.D.4    Szalay, A.A.5    Wang, E.6


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