-
1
-
-
73949153243
-
20-hy-droxy-5, 8, 11, 14-eicosatetraenoic acid mediates endothelial dysfunction via IKB kinase-dependent endothelial nitric-oxide synthase uncoupling
-
Cheng, J., Wu, C. C, Gotlinger, K H., Zhang, F., Falck, J. R., Narsimhaswamy, D., and Schwartzman, M. L. (2010) 20-hy-droxy-5, 8, 11, 14-eicosatetraenoic acid mediates endothelial dysfunction via IKB kinase-dependent endothelial nitric-oxide synthase uncoupling. J. Pharmacol. Exp. Ther. 332, 57-65
-
(2010)
J. Pharmacol. Exp. Ther.
, vol.332
, pp. 57-65
-
-
Cheng, J.1
Wu, C.C.2
Gotlinger, K.H.3
Zhang, F.4
Falck, J.R.5
Narsimhaswamy, D.6
Schwartzman, M.L.7
-
2
-
-
33748439111
-
Mechanisms of activation of eNOS by 20-HETE and VEGF in bovine pulmonary artery endothelial cells
-
DOI 10.1152/ajplung.00424.2005
-
Chen, Y., Medhora, M., Falck, J. R., Pritchard, K A., Jr., and Jacobs, E. R. (2006) Mechanisms of activation of eNOS by 20-HETE and VEGF in bovine pulmonary artery endothelial cells. Am. J. Physiol. Lung Cell. Mol. Physiol. 291, L378-L385 (Pubitemid 44343713)
-
(2006)
American Journal of Physiology - Lung Cellular and Molecular Physiology
, vol.291
, Issue.3
-
-
Chen, Y.1
Medhora, M.2
Falck, J.R.3
Pritchard Jr., K.A.4
Jacobs, E.R.5
-
3
-
-
27744551500
-
Role of 20-hydroxyeicosatetraenoic acid (20-HETE) in vascular system
-
DOI 10.1540/jsmr.41.175
-
Miyata, N., and Roman, R. J. (2005) Role of 20-hydroxyeicosa-tetraenoic acid (20-HETE) in vascular system. J. Smooth Muscle Res. 41, 175-193 (Pubitemid 41596358)
-
(2005)
Journal of Smooth Muscle Research
, vol.41
, Issue.4
, pp. 175-193
-
-
Miyata, N.1
Roman, R.J.2
-
4
-
-
77958067577
-
+ channel via a PKC-dependent mechanism in cardi-omyocytes
-
+ channel via a PKC-dependent mechanism in cardi-omyocytes. Am. J. Physiol. Heart Circ. Physiol. 299, H1109-H1117
-
(2010)
Am. J. Physiol. Heart Circ. Physiol.
, vol.299
-
-
Zeng, Q.1
Han, Y.2
Bao, Y.3
Li, W.4
Li, X.5
Shen, X.6
Wang, X.7
Yao, F.8
O'Rourke, S.T.9
Sun, C.10
-
5
-
-
39149110293
-
20-Hydroxyeicosatetraenoic acid causes endothelial dysfunction via eNOS uncoupling
-
DOI 10.1152/ajpheart.01172.2007
-
Cheng, J., Ou, J. S., Singh, H., Falck, J. R., Narsimhaswamy, D., Pritchard, K A., Jr., and Schwartzman, M. L. (2008) 20-hydroxy-eicosatetraenoic acid causes endothelial dysfunction via eNOS uncoupling. Am. J. Physiol. Heart Circ. Physiol. 294, H1018-H1026 (Pubitemid 351253316)
-
(2008)
American Journal of Physiology - Heart and Circulatory Physiology
, vol.294
, Issue.2
-
-
Cheng, J.1
Ou, J.-S.2
Singh, H.3
Falck, J.R.4
Narsimhaswamy, D.5
Pritchard Jr., K.A.6
Schwartzman, M.L.7
-
6
-
-
34250847145
-
Vascular cytochrome P450 4A expression and 20-hydroxyeicosatetraenoic acid synthesis contribute to endothelial dysfunction in androgen-induced hypertension
-
DOI 10.1161/HYPERTENSIONAHA.107.089599, PII 0000426820070700000022
-
Singh, H., Cheng, J., Deng, H., Kemp, R., Ishizuka, T., Nasjletti, A, and Schwartzman, M. L. (2007) Vascular cytochrome P450 4A expression and 20-hydroxyeicosatetraenoic acid synthesis contribute to endothelial dysfunction in androgen-induced hypertension. Hypertension 50, 123-129 (Pubitemid 46986020)
-
(2007)
Hypertension
, vol.50
, Issue.1
, pp. 123-129
-
-
Singh, H.1
Cheng, J.2
Deng, H.3
Kemp, R.4
Ishizuka, T.5
Nasjletti, A.6
Schwartzman, M.L.7
-
7
-
-
33748435644
-
VEGF-induced relaxation of pulmonary arteries is mediated by endothelial cytochrome P-450 hydroxylase
-
DOI 10.1152/ajplung.00265.2004
-
Jacobs, E. R., Zhu, D., Gruenloh, S., Lopez, B., and Medhora, M. (2006) VEGF-induced relaxation of pulmonary arteries is mediated by endothelial cytochrome P-450 hydroxylase. Am. J. Physiol. Lung Cell. Mol. Physiol. 291, L369-L377 (Pubitemid 44343712)
-
(2006)
American Journal of Physiology - Lung Cellular and Molecular Physiology
, vol.291
, Issue.3
-
-
Jacobs, E.R.1
Zhu, D.2
Gruenloh, S.3
Lopez, B.4
Medhora, M.5
-
8
-
-
45849122077
-
20-HETE increases superoxide production and activates NAPDH oxidase in pulmonary artery endothelial cells
-
Medhora, M., Chen, Y., Gruenloh, S., Harland, D., Bodiga, S., Zielonka, J., Gebremedhin, D., Gao, Y, Falck, J. R., Anjaiah, S., and Jacobs, E. R. (2008) 20-HETE increases superoxide production and activates NAPDH oxidase in pulmonary artery endothelial cells. Am. J. Physiol. Lung Cell. Mol. Physiol. 294, L902-L911
-
(2008)
Am. J. Physiol. Lung Cell. Mol. Physiol.
, vol.294
-
-
Medhora, M.1
Chen, Y.2
Gruenloh, S.3
Harland, D.4
Bodiga, S.5
Zielonka, J.6
Gebremedhin, D.7
Gao, Y.8
Falck, J.R.9
Anjaiah, S.10
Jacobs, E.R.11
-
9
-
-
33947389882
-
Activation of vascular endothelial growth factor through reactive oxygen species mediates 20-hydroxyeicosatetraenoic acid-induced endothelial cell proliferation
-
DOI 10.1124/jpet.106.115360
-
Guo, A. M., Arbab, A. S., Falck, J. R., Chen, P., Edwards, P. A., Roman, R. J., and Scicli, A. G. (2007) Activation of vascular endothelial growth factor through reactive oxygen species mediates 20-hydroxyeicosatetraenoic acid-induced endothelial cell proliferation. J. Pharmacol. Exp. Ther. 321, 18-27 (Pubitemid 46456964)
-
(2007)
Journal of Pharmacology and Experimental Therapeutics
, vol.321
, Issue.1
, pp. 18-27
-
-
Guo, A.M.1
Arbab, A.S.2
Falck, J.R.3
Chen, P.4
Edwards, P.A.5
Roman, R.J.6
Scicli, A.G.7
-
10
-
-
13244292649
-
Inhibitors of cytochrome P450 4A suppress angiogenic responses
-
Chen, P., Guo, M., Wygle, D., Edwards, P. A., Falck, J. R., Roman, R. J., and Scicli, A. G. (2005) Inhibitors of cytochrome P450 4A suppress angiogenic responses. Am. J. Pathol. 166, 615-624 (Pubitemid 40189056)
-
(2005)
American Journal of Pathology
, vol.166
, Issue.2
, pp. 615-624
-
-
Chen, P.1
Guo, M.2
Wygle, D.3
Edwards, P.A.4
Falck, J.R.5
Roman, R.J.6
Scicli, A.G.7
-
11
-
-
54049136052
-
20-HETE mediates proliferation of renal epithelial cells in polycystic kidney disease
-
Park, F., Sweeney, W. E., Jia, G., Roman, R. J., and Avner, E. D. (2008) 20-HETE mediates proliferation of renal epithelial cells in polycystic kidney disease. J. Am. Soc. Nephrol. 19, 1929-1939
-
(2008)
J. Am. Soc. Nephrol.
, vol.19
, pp. 1929-1939
-
-
Park, F.1
Sweeney, W.E.2
Jia, G.3
Roman, R.J.4
Avner, E.D.5
-
12
-
-
0037404487
-
CYP4A metabolites of arachidonic acid and VEGF are mediators of skeletal muscle angiogenesis
-
Amaral, S. L., Maier, K G., Schippers, D. N., Roman, R. J., and Greene, A. S. (2003) CYP4A metabolites of arachidonic acid and VEGF are mediators of skeletal muscle angiogenesis. Am. J. Physiol. Heart Circ. Physiol. 284, H1528-H1535 (Pubitemid 36460763)
-
(2003)
American Journal of Physiology - Heart and Circulatory Physiology
, vol.284
, Issue.5
-
-
Amaral, S.L.1
Maier, K.G.2
Schippers, D.N.3
Roman, R.J.4
Greene, A.S.5
-
13
-
-
1042279546
-
Smooth muscle-specific expression of cyp4a1 induces endothelial sprouting in renal arterial microvessels
-
DOI 10.1161/01.RES.0000111523.12842.FC
-
Jiang, M., Mezentsev, A., Kemp, R., Byun, K, Falck, J. R., Miano, J. M., Nasjletti, A., Abraham, N. G., and Laniado-Schwartzman, M. (2004) Smooth muscle-specific expression of CYP4A1 induces endothelial sprouting in renal arterial microvessels. Circ. Res. 94, 167-174 (Pubitemid 38197448)
-
(2004)
Circulation Research
, vol.94
, Issue.2
, pp. 167-174
-
-
Jiang, M.1
Mezentsev, A.2
Kemp, R.3
Byun, K.4
Falck, J.R.5
Miano, J.M.6
Nasjletti, A.7
Abraham, N.G.8
Laniado-Schwartzman, M.9
-
14
-
-
80054697990
-
Cytochrome P450 omega-hydroxylase promotes angiogenesis and metastasis by upregulation of VEGF and MMP-9 in non-small cell lung cancer
-
Yu, W., Chen, L., Yang, Y. Q., Falck, J. R., Guo, A. M., Li, Y, and Yang, J. (2011) Cytochrome P450 omega-hydroxylase promotes angiogenesis and metastasis by upregulation of VEGF and MMP-9 in non-small cell lung cancer. Cancer Chemother. Pharmacol. 68, 619-629
-
(2011)
Cancer Chemother. Pharmacol.
, vol.68
, pp. 619-629
-
-
Yu, W.1
Chen, L.2
Yang, Y.Q.3
Falck, J.R.4
Guo, A.M.5
Li, Y.6
Yang, J.7
-
15
-
-
37349011542
-
20-Hydroxyeicosatetraenoic acid stimulates nuclear factor-κB activation and the production of inflammatory cytokines in human endothelial cells
-
DOI 10.1124/jpet.107.130336
-
Ishizuka, T., Cheng, J., Singh, H., Vitto, M. D., Manthati, V. L., Falck, J. R., and Laniado-Schwartzman, M. (2008) 20-hydroxyeicosatetraenoic acid stimulates nuclear factor-KB activation and the production of inflammatory cytokines in human endothelial cells. J. Pharmacol. Exp. Ther. 324, 103-110 (Pubitemid 350294158)
-
(2008)
Journal of Pharmacology and Experimental Therapeutics
, vol.324
, Issue.1
, pp. 103-110
-
-
Ishizuka, T.1
Cheng, J.2
Singh, H.3
Vitto, M.D.4
Manthati, V.L.5
Falck, J.R.6
Laniado-Schwartzman, M.7
-
16
-
-
78650281503
-
Inhibition of 20-HETE synthesis and action protects the kidney from ischemia/reper-fusion injury
-
Hoff, U., Lukitsch, I., Chaykovska, L., Ladwig, M., Arnold, C, Manthati, V. L., Fuller, T. F., Schneider, W., Gollasch, M., Muller, D. N., Flemming, B., Seeliger, E., Luft, F. C., Falck, J. R., Dragun, D., and Schunck, W. H. (2011) Inhibition of 20-HETE synthesis and action protects the kidney from ischemia/reper-fusion injury. Kidney Int. 79, 57-65
-
(2011)
Kidney Int.
, vol.79
, pp. 57-65
-
-
Hoff, U.1
Lukitsch, I.2
Chaykovska, L.3
Ladwig, M.4
Arnold, C.5
Manthati, V.L.6
Fuller, T.F.7
Schneider, W.8
Gollasch, M.9
Muller, D.N.10
Flemming, B.11
Seeliger, E.12
Luft, F.C.13
Falck, J.R.14
Dragun, D.15
Schunck, W.H.16
-
17
-
-
0031808169
-
Metabolism of arachidonic acid to 20-hydroxy-5,8,11,14-eicosatetraenoic acid by P450 enzymes in human liver: Involvement of CYP4F2 and CYP4A11
-
Powell, P. K., Wolf, I., Jin, R., and Lasker, J. M. (1998) Metabolism of arachidonic acid to 20-hydroxy-5, 8, 11, 14-eicosa-tetraenoic acid by P450 enzymes in human liver: involvement of CYP4F2 and CYP4A11. J. Pharmacol. Exp. Ther. 285, 1327-1336 (Pubitemid 28277936)
-
(1998)
Journal of Pharmacology and Experimental Therapeutics
, vol.285
, Issue.3
, pp. 1327-1336
-
-
Powell, P.K.1
Wolf, I.2
Jin, R.3
Lasker, J.M.4
-
18
-
-
0034635521
-
Formation of 20-hydroxyeicosatetraenoic acid, a vasoactive and natriuretic eicosanoid, in human kidney. Role of CYP4F2 and CYP4A11
-
DOI 10.1074/jbc.275.6.4118
-
Lasker, J. M., Chen, W. B., Wolf, I., Bloswick, B. P., Wilson, P. D., and Powell, P. K. (2000) Formation of 20-hydroxyeicosatetra-enoic acid, a vasoactive and natriuretic eicosanoid, in human kidney. Role of Cyp4F2 and Cyp4A11. J. Biol. Chem. 275, 4118-4126 (Pubitemid 30094644)
-
(2000)
Journal of Biological Chemistry
, vol.275
, Issue.6
, pp. 4118-4126
-
-
Lasker, J.M.1
Chen, W.B.2
Wolf, I.3
Bloswick, B.P.4
Wilson, P.D.5
Powell, P.K.6
-
19
-
-
42349090786
-
A single nucleotide polymorphism in the CYP4F2 but not CYP4A11 gene is associated with increased 20-HETE excretion and blood pressure
-
DOI 10.1161/HYPERTENSIONAHA.107.104463, PII 0000426820080500000025
-
Ward, N. C., Tsai, I. J., Barden, A., van Bockxmeer, F. M., Puddey, I. B., Hodgson, J. M., and Croft, K. D. (2008) A single nucleotide polymorphism in the CYP4F2 but not CYP4A11 gene is associated with increased 20-HETE excretion and blood pressure. Hypertension 51, 1393-1398 (Pubitemid 351555955)
-
(2008)
Hypertension
, vol.51
, Issue.5
, pp. 1393-1398
-
-
Ward, N.C.1
Tsai, I.-J.2
Barden, A.3
Van Bockxmeer, F.M.4
Puddey, I.B.5
Hodgson, J.M.6
Croft, K.D.7
-
20
-
-
77952673811
-
CYP4F2 gene V433M polymorphism is associated with ischemic stroke in the male northern Chinese Han population
-
Deng, S., Zhu, G., Liu, F., Zhang, H., Qin, X., Li, L., and Zhiyi, H. (2010) CYP4F2 gene V433M polymorphism is associated with ischemic stroke in the male northern Chinese Han population. Prog. Neuropsychopharmacol. Biol. Psychiatry 34, 664-668
-
(2010)
Prog. Neuropsychopharmacol. Biol. Psychiatry
, vol.34
, pp. 664-668
-
-
Deng, S.1
Zhu, G.2
Liu, F.3
Zhang, H.4
Qin, X.5
Li, L.6
Zhiyi, H.7
-
21
-
-
44349119245
-
Association of a functional cytochrome P450 4F2 haplo-type with urinary 20-HETE and hypertension
-
Liu, H., Zhao, Y., Nie, D., Shi, J., Fu, L., Li, Y., Yu, D., and Lu, J. (2008) Association of a functional cytochrome P450 4F2 haplo-type with urinary 20-HETE and hypertension. J. Am. Soc. Nephrol. 19, 714-721
-
(2008)
J. Am. Soc. Nephrol.
, vol.19
, pp. 714-721
-
-
Liu, H.1
Zhao, Y.2
Nie, D.3
Shi, J.4
Fu, L.5
Li, Y.6
Yu, D.7
Lu, J.8
-
22
-
-
67349175768
-
Overexpression of cytochrome P450 4F2 in mice increases 20-hydroxyeicosatetraenoic acid production and arterial blood pressure
-
Liu, X., Zhao, Y., Wang, L., Yang, X., Zheng, Z., Zhang, Y., Chen, F., and Liu, H. (2009) Overexpression of cytochrome P450 4F2 in mice increases 20-hydroxyeicosatetraenoic acid production and arterial blood pressure. Kidney. Int. 75, 1288-1296
-
(2009)
Kidney. Int.
, vol.75
, pp. 1288-1296
-
-
Liu, X.1
Zhao, Y.2
Wang, L.3
Yang, X.4
Zheng, Z.5
Zhang, Y.6
Chen, F.7
Liu, H.8
-
23
-
-
15244348288
-
Urinary 20-hydroxyeicosatetraenoic acid excretion is associated with oxidative stress in hypertensive subjects
-
DOI 10.1016/j.freeradbiomed.2004.12.024
-
Ward, N. C., Puddey, I. B., Hodgson, J. M., Beilin, L. J., and Croft, K. D. (2005) Urinary 20-hydroxyeicosatetraenoic acid excretion is associated with oxidative stress in hypertensive subjects. Free Radic. Biol. Med. 38, 1032-1036 (Pubitemid 40386549)
-
(2005)
Free Radical Biology and Medicine
, vol.38
, Issue.8
, pp. 1032-1036
-
-
Ward, N.C.1
Puddey, I.B.2
Hodgson, J.M.3
Beilin, L.J.4
Croft, K.D.5
-
24
-
-
3342875746
-
Urinary 20-hydroxyeicosatetraenoic acid is associated with endothelial dysfunction in humans
-
DOI 10.1161/01.CIR.0000136808.72912.D9
-
Ward, N. C., Rivera, J., Hodgson, J., Puddey, I. B., Beilin, L. J., Falck, J. R., and Croft, K. D. (2004) Urinary 20-hydroxyeicosa-tetraenoic acid is associated with endothelial dysfunction in humans. Circulation 110, 438-443 (Pubitemid 38993854)
-
(2004)
Circulation
, vol.110
, Issue.4
, pp. 438-443
-
-
Ward, N.C.1
Rivera, J.2
Hodgson, J.3
Puddey, I.B.4
Beilin, L.J.5
Falck, J.R.6
Croft, K.D.7
-
25
-
-
84875052505
-
Cytochrome P450-derived eicosanoids and vascular dysfunction in coronary artery disease patients
-
Schuck, R. N., Theken, K. N., Edin, M. L., Caughey, M., Bass, A., Ellis, K., Tran, B., Steele, S., Simmons, B. P., Lih, F. B., Tomer, K. B., Wu, M. C., Hinderliter, A. L., Stouffer, G. A., Zeldin, D. C., and Lee, C. R. (2013) Cytochrome P450-derived eicosanoids and vascular dysfunction in coronary artery disease patients. Atherosclerosis 227, 442-448
-
(2013)
Atherosclerosis
, vol.227
, pp. 442-448
-
-
Schuck, R.N.1
Theken, K.N.2
Edin, M.L.3
Caughey, M.4
Bass, A.5
Ellis, K.6
Tran, B.7
Steele, S.8
Simmons, B.P.9
Lih, F.B.10
Tomer, K.B.11
Wu, M.C.12
Hinderliter, A.L.13
Stouffer, G.A.14
Zeldin, D.C.15
Lee, C.R.16
-
26
-
-
77957831701
-
Endothelial expression of human cytochrome P450 epoxygenases lowers blood pressure and attenuates hypertension-induced renal injury in mice
-
Lee, C. R., Imig, J. D., Edin, M. L., Foley, J., DeGraff, L. M., Bradbury, J. A., Graves, J. P., Lih, F. B., Clark, J., Myers, P., Perrow, A. L., Lepp, A. N., Kannon, M. A., Ronnekleiv, O. K., Alkayed, N. J., Falck, J. R., Tomer, K. B., and Zeldin, D. C. (2010) Endothelial expression of human cytochrome P450 epoxygenases lowers blood pressure and attenuates hypertension-induced renal injury in mice. FASEB J. 24, 3770-3781
-
(2010)
FASEB J.
, vol.24
, pp. 3770-3781
-
-
Lee, C.R.1
Imig, J.D.2
Edin, M.L.3
Foley, J.4
Degraff, L.M.5
Bradbury, J.A.6
Graves, J.P.7
Lih, F.B.8
Clark, J.9
Myers, P.10
Perrow, A.L.11
Lepp, A.N.12
Kannon, M.A.13
Ronnekleiv, O.K.14
Alkayed, N.J.15
Falck, J.R.16
Tomer, K.B.17
Zeldin, D.C.18
-
27
-
-
57349108805
-
Increased blood pressure in mice lacking cytochrome P450 2J5
-
Athirakul, K., Bradbury, J. A., Graves, J. P., DeGraff, L. M., Ma, J., Zhao, Y., Couse, J. F., Quigley, R., Harder, D. R., Zhao, X., Imig, J. D., Pedersen, T. L., Newman, J. W., Hammock, B. D., Conley, A. J., Korach, K. S., Coffman, T. M., and Zeldin, D. C. (2008) Increased blood pressure in mice lacking cytochrome P450 2J5. FASEB J. 22, 4096-4108
-
(2008)
FASEB J.
, vol.22
, pp. 4096-4108
-
-
Athirakul, K.1
Bradbury, J.A.2
Graves, J.P.3
Degraff, L.M.4
Ma, J.5
Zhao, Y.6
Couse, J.F.7
Quigley, R.8
Harder, D.R.9
Zhao, X.10
Imig, J.D.11
Pedersen, T.L.12
Newman, J.W.13
Hammock, B.D.14
Conley, A.J.15
Korach, K.S.16
Coffman, T.M.17
Zeldin, D.C.18
-
28
-
-
80053919098
-
Endothelial expression of human cytochrome P450 epoxygenase CYP2C8 increases susceptibility to ischemia-reperfusion injury in isolated mouse heart
-
Edin, M. L., Wang, Z., Bradbury, J. A., Graves, J. P., Lih, F. B., DeGraff, L. M., Foley, J. F., Torphy, R., Ronnekleiv, O. K., Tomer, K. B., Lee, C. R., and Zeldin, D. C. (2011) Endothelial expression of human cytochrome P450 epoxygenase CYP2C8 increases susceptibility to ischemia-reperfusion injury in isolated mouse heart. FASEB J. 25, 3436-3447
-
(2011)
FASEB J.
, vol.25
, pp. 3436-3447
-
-
Edin, M.L.1
Wang, Z.2
Bradbury, J.A.3
Graves, J.P.4
Lih, F.B.5
Degraff, L.M.6
Foley, J.F.7
Torphy, R.8
Ronnekleiv, O.K.9
Tomer, K.B.10
Lee, C.R.11
Zeldin, D.C.12
-
29
-
-
0035710746
-
-ΔΔCT method
-
DOI 10.1006/meth.2001.1262
-
Livak, K. J., and Schmittgen, T. D. (2001) Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) method. Methods 25, 402-408 (Pubitemid 34164012)
-
(2001)
Methods
, vol.25
, Issue.4
, pp. 402-408
-
-
Livak, K.J.1
Schmittgen, T.D.2
-
30
-
-
33646163015
-
Endothelial dysfunction and hypertension in rats transduced with CYP4A2 adenovirus
-
Wang, J. S., Singh, H., Zhang, F., Ishizuka, T., Deng, H., Kemp, R., Wolin, M. S., Hintze, T. H., Abraham, N. G., Nasjletti, A., and Laniado-Schwartzman, M. (2006) Endothelial dysfunction and hypertension in rats transduced with CYP4A2 adenovirus. Circ. Res. 98, 962-969
-
(2006)
Circ. Res.
, vol.98
, pp. 962-969
-
-
Wang, J.S.1
Singh, H.2
Zhang, F.3
Ishizuka, T.4
Deng, H.5
Kemp, R.6
Wolin, M.S.7
Hintze, T.H.8
Abraham, N.G.9
Nasjletti, A.10
Laniado-Schwartzman, M.11
-
31
-
-
1542313876
-
Interleukin-6 induces oxidative stress and endothehal dysfunction by overexpression of the angiotensin II type 1 receptor
-
DOI 10.1161/01.RES.0000115557.25127.8D
-
Wassmann, S., Stumpf, M., Strehlow, K., Schmid, A., Schieffer, B., Bohm, M., and Nickenig, G. (2004) Interleukin-6 induces oxidative stress and endothelial dysfunction by overexpression of the angiotensin II type 1 receptor. Circ. Res. 94, 534-541 (Pubitemid 38326289)
-
(2004)
Circulation Research
, vol.94
, Issue.4
, pp. 534-541
-
-
Wassmann, S.1
Stumpf, M.2
Strehlow, K.3
Schmid, A.4
Schieffer, B.5
Bohm, M.6
Nickenig, G.7
-
32
-
-
58149385775
-
Interleukin-6 mediates the increase in NADPH-oxidase in the ketamine model of schizophrenia
-
Behrens, M. M., Ali, S. S., and Dugan, L. L. (2008) Interleukin-6 mediates the increase in NADPH-oxidase in the ketamine model of schizophrenia. J. Neurosci. 28, 13957-13966
-
(2008)
J. Neurosci.
, vol.28
, pp. 13957-13966
-
-
Behrens, M.M.1
Ali, S.S.2
Dugan, L.L.3
-
33
-
-
33745189788
-
Novel Nox inhibitor VAS2870 attenuates PDGF-dependent smooth muscle cell chemotaxis, but not proliferation
-
ten Freyhaus, H., Huntgeburth, M., Wingler, K., Schnitker, J., Baumer, A. T., Vantler, M., Bekhite, M. M., Wartenberg, M., Sauer, H., and Rosenkranz, S. (2006) Novel Nox inhibitor VAS2870 attenuates PDGF-dependent smooth muscle cell chemotaxis, but not proliferation. Cardiovasc. Res. 71, 331-341
-
(2006)
Cardiovasc. Res.
, vol.71
, pp. 331-341
-
-
Ten Freyhaus, H.1
Huntgeburth, M.2
Wingler, K.3
Schnitker, J.4
Baumer, A.T.5
Vantler, M.6
Bekhite, M.M.7
Wartenberg, M.8
Sauer, H.9
Rosenkranz, S.10
-
34
-
-
33646107369
-
VEGF receptor signalling-in control of vascular function
-
Olsson, A. K., Dimberg, A., Kreuger, J., and Claesson-Welsh, L. (2006) VEGF receptor signalling-in control of vascular function. Nat. Rev. Mol. Cell Biol. 7, 359-371
-
(2006)
Nat. Rev. Mol. Cell Biol.
, vol.7
, pp. 359-371
-
-
Olsson, A.K.1
Dimberg, A.2
Kreuger, J.3
Claesson-Welsh, L.4
-
35
-
-
84864143777
-
Disturbed ratio of renal 20-HETE/EETs is involved in androgen-induced hypertension in cytochrome P450 4F2 transgenic mice
-
Liu, X., Wu, J., Liu, H., Lai, G., and Zhao, Y. (2012) Disturbed ratio of renal 20-HETE/EETs is involved in androgen-induced hypertension in cytochrome P450 4F2 transgenic mice. Gene 505, 352-359
-
(2012)
Gene
, vol.505
, pp. 352-359
-
-
Liu, X.1
Wu, J.2
Liu, H.3
Lai, G.4
Zhao, Y.5
-
36
-
-
84864280330
-
Induction of angio-tensin-converting enzyme and activation of the renin-angiotensin system contribute to 20-hydroxyeicosatetraenoic acid-mediated endothelial dysfunction
-
Cheng, J., Garcia, V., Ding, Y., Wu, C. C., Thakar, K., Falck, J. R., Ramu, E., and Schwartzman, M. L. (2012) Induction of angio-tensin-converting enzyme and activation of the renin-angiotensin system contribute to 20-hydroxyeicosatetraenoic acid-mediated endothelial dysfunction. Arterioscler. Thromb. Vasc. Biol. 32, 1917-1924
-
(2012)
Arterioscler. Thromb. Vasc. Biol.
, vol.32
, pp. 1917-1924
-
-
Cheng, J.1
Garcia, V.2
Ding, Y.3
Wu, C.C.4
Thakar, K.5
Falck, J.R.6
Ramu, E.7
Schwartzman, M.L.8
-
37
-
-
70349648137
-
Endothelial-specific CYP4A2 overexpression leads to renal injury and hypertension via increased production of 20-HETE
-
Inoue, K., Sodhi, K., Puri, N., Gotlinger, K. H., Cao, J., Rezzani, R., Falck, J. R., Abraham, N. G., and Laniado-Schwartzman, M. (2009) Endothelial-specific CYP4A2 overexpression leads to renal injury and hypertension via increased production of 20-HETE. Am. J. Physiol. Renal Physiol. 297, F875-F884
-
(2009)
Am. J. Physiol. Renal Physiol.
, vol.297
-
-
Inoue, K.1
Sodhi, K.2
Puri, N.3
Gotlinger, K.H.4
Cao, J.5
Rezzani, R.6
Falck, J.R.7
Abraham, N.G.8
Laniado-Schwartzman, M.9
-
39
-
-
0035678477
-
Oxidative stress in arterial hypertension role of NAD(P)H oxidase
-
Zalba, G., San Jose, G., Moreno, M. U., Fortuno, M. A., Fortuno, A, Beaumont, F. J., and Diez, J. (2001) Oxidative stress in arterial hypertension: role of NAD(P)H oxidase. Hypertension38, 1395-1399 (Pubitemid 34033422)
-
(2001)
Hypertension
, vol.38
, Issue.6
, pp. 1395-1399
-
-
Zalba, G.1
Jose, G.S.2
Moreno, M.U.3
Fortuno, M.A.4
Fortuno, A.5
Beaumont, F.J.6
Diez, J.7
-
40
-
-
77950896739
-
NADPH oxidases: Functions and pathologies in the vasculature
-
Lassegue, B., and Griendling, K. K. (2010) NADPH oxidases: functions and pathologies in the vasculature. Arterioscler. Thromb. Vasc. Biol. 30, 653-661
-
(2010)
Arterioscler. Thromb. Vasc. Biol.
, vol.30
, pp. 653-661
-
-
Lassegue, B.1
Griendling, K.K.2
-
41
-
-
0031613013
-
Cytochrome P-450 metabolites mediate norepinephrine-induced mitogenic signaling
-
Uddin, M. R., Muthalif, M. M., Karzoun, N. A., Benter, I. F., and Malik, K. U. (1998) Cytochrome P-450 metabolites mediate norepinephrine-induced mitogenic signaling. Hypertension 31, 242-247
-
(1998)
Hypertension
, vol.31
, pp. 242-247
-
-
Uddin, M.R.1
Muthalif, M.M.2
Karzoun, N.A.3
Benter, I.F.4
Malik, K.U.5
-
42
-
-
68049101447
-
20-HETE can act as a nonhypoxic regulator of HIF-1a in human microvascular endothelial cells
-
Guo, A. M., Scicli, G., Sheng, J., Falck, J. C, Edwards, P. A., and Scicli, A. G. (2009) 20-HETE can act as a nonhypoxic regulator of HIF-1a in human microvascular endothelial cells. Am. J. Physiol. Heart Circ. Physiol. 297, H602-H613
-
(2009)
Am. J. Physiol. Heart Circ. Physiol.
, vol.297
-
-
Guo, A.M.1
Scicli, G.2
Sheng, J.3
Falck, J.C.4
Edwards, P.A.5
Scicli, A.G.6
-
43
-
-
71949116212
-
Down-regulation of 20-HETE synthesis and signaling inhibits renal adenocarcinoma cell proliferation and tumor growth
-
Alexanian, A., Rufanova, V. A., Miller, B., Flasch, A., Roman, R. J., and Sorokin, A. (2009) Down-regulation of 20-HETE synthesis and signaling inhibits renal adenocarcinoma cell proliferation and tumor growth. Anticancer Res. 29, 3819-3824
-
(2009)
Anticancer Res.
, vol.29
, pp. 3819-3824
-
-
Alexanian, A.1
Rufanova, V.A.2
Miller, B.3
Flasch, A.4
Roman, R.J.5
Sorokin, A.6
-
44
-
-
84864656181
-
20-HETE-producing enzymes are up-regulated in human cancers
-
Alexanian, A., Miller, B., Roman, R. J., and Sorokin, A. (2012) 20-HETE-producing enzymes are up-regulated in human cancers. Cancer Genomics Proteomics 9, 163-169
-
(2012)
Cancer Genomics Proteomics
, vol.9
, pp. 163-169
-
-
Alexanian, A.1
Miller, B.2
Roman, R.J.3
Sorokin, A.4
|