Novel Nox inhibitor VAS2870 attenuates PDGF-dependent smooth muscle cell chemotaxis, but not proliferation

Cardiovascular Research

Volumn 71, Issue 2, 2006, Pages 331-341

  ten Freyhaus, Henrik ^a   Huntgeburth, Michael ^a   Wingler, Kirstin ^b   Schnitker, Jessika ^a   Bäumer, Anselm T ^a   Vantler, Marius ^a   Bekhite, Mohamed M ^c   Wartenberg, Maria ^c   Sauer, Heinrich ^d   Rosenkranz, Stephan ^a,c  

^a UNIVERSITY HOSPITAL OF COLOGNE   (Germany)

^b Vasopharm BIOTECH GmbH   (Germany)

^c UNIVERSITY OF COLOGNE   (Germany)

^d JUSTUS LIEBIG UNIVERSITY   (Germany)

Author keywords

Atherosclerosis; NAD(P)H oxidase; Platelet derived growth factor; ROS; Src

Indexed keywords

3 BENZYL 7 (2 BENZOXAZOLYL)THIO 1,2,3 TRIAZOLO[4,5 D]PYRIMIDINE; BROXURIDINE; DICHLOROFLUORESCEIN; GROWTH FACTOR; LUCIGENIN; MITOGEN ACTIVATED PROTEIN KINASE; OXIDOREDUCTASE INHIBITOR; PHOSPHOSPECIFIC ANTIBODY; PLATELET DERIVED GROWTH FACTOR; PROTEIN KINASE B; PROTEIN TYROSINE KINASE; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; UNCLASSIFIED DRUG; VAS 2870;

ANIMAL CELL; ARTICLE; CELL CYCLE; CELL CYCLE PROGRESSION; CELL FUNCTION; CELL MIGRATION; CELL PROLIFERATION; CHEMOLUMINESCENCE; CHEMOTAXIS; CONCENTRATION (PARAMETERS); CONFOCAL LASER MICROSCOPY; CONTROLLED STUDY; DNA SYNTHESIS; ENZYME ACTIVATION; ENZYME ACTIVITY; INCUBATION TIME; NONHUMAN; OXIDATION REDUCTION REACTION; PRIORITY JOURNAL; PROTEIN FUNCTION; RAT; SENSITIVITY ANALYSIS; SIGNAL TRANSDUCTION; SMOOTH MUSCLE FIBER; VASCULAR SMOOTH MUSCLE; WESTERN BLOTTING;

EID: 33745189788     PISSN: 00086363     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cardiores.2006.01.022     Document Type: Article

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