메뉴 건너뛰기




Volumn 9, Issue 4, 2012, Pages 163-169

20-HETE-producing enzymes are up-regulated in human cancers

Author keywords

20 HETE; 20 Hydroxyeicosatetraenoic acid; CYP4A F; Eicosanoids; HRPTEC cells; Ovarian cancer; Ras

Indexed keywords

20 HYDROXYICOSATETRAENOIC ACID; CYTOCHROME; CYTOCHROME P450 4A; CYTOCHROME P450 4F; MESSENGER RNA; UNCLASSIFIED DRUG;

EID: 84864656181     PISSN: 11096535     EISSN: 17906245     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (52)

References (17)
  • 1
    • 29244449354 scopus 로고    scopus 로고
    • Prostaglandins and cancer
    • DOI 10.1136/gut.2004.047100
    • Wang D and Dubois RN: Prostaglandins and cancer. Gut 55: 115-122, 2006. (Pubitemid 41820645)
    • (2006) Gut , vol.55 , Issue.1 , pp. 115-122
    • Wang, D.1    Dubois, R.N.2
  • 2
    • 77649179672 scopus 로고    scopus 로고
    • Eicosanoids and cancer
    • Wang D and Dubois RN: Eicosanoids and cancer. Nat Rev Cancer 10: 181-193, 2010.
    • (2010) Nat Rev Cancer , vol.10 , pp. 181-193
    • Wang, D.1    Dubois, R.N.2
  • 3
    • 0029177711 scopus 로고
    • 20-Hydroxyeicosatetraenoic acid is formed in response to EGF and is a mitogen in rat proximal tubule
    • Lin F, Rios A, Falck JR, Belosludtsev Y and Schwartzman ML: 20-Hydroxyeicosatetraenoic acid is formed in response to EGF and is a mitogen in rat proximal tubule. Am J Physiol 269: F806-F816, 1995.
    • (1995) Am J Physiol , vol.269
    • Lin, F.1    Rios, A.2    Falck, J.R.3    Belosludtsev, Y.4    Schwartzman, M.L.5
  • 5
    • 33947389882 scopus 로고    scopus 로고
    • Activation of vascular endothelial growth factor through reactive oxygen species mediates 20-hydroxyeicosatetraenoic acid-induced endothelial cell proliferation
    • DOI 10.1124/jpet.106.115360
    • Guo AM, Arbab AS, Falck JR, Chen P, Edwards PA, Roman RJ and Scicli AG: Activation of vascular endothelial growth factor through reactive oxygen species mediates 20-hydroxyeicosatetraenoic acid-induced endothelial cell proliferation. J Pharmacol Exp Ther 321: 18-27, 2007. (Pubitemid 46456964)
    • (2007) Journal of Pharmacology and Experimental Therapeutics , vol.321 , Issue.1 , pp. 18-27
    • Guo, A.M.1    Arbab, A.S.2    Falck, J.R.3    Chen, P.4    Edwards, P.A.5    Roman, R.J.6    Scicli, A.G.7
  • 6
    • 33645122883 scopus 로고    scopus 로고
    • 9L gliosarcoma cell proliferation and tumor growth in rats are suppressed by N-hydroxy-N′-(4-butyl-2-methylphenol) formamidine (HET0016), a selective inhibitor of CYP4A
    • Guo M, Roman RJ, Fenstermacher JD, Brown SL, Falck JR, Arbab AS, Edwards PA and Scicli AG: 9L gliosarcoma cell proliferation and tumor growth in rats are suppressed by N-hydroxy-N′-(4-butyl-2-methylphenol) formamidine (HET0016), a selective inhibitor of CYP4A. J Pharmacol Exp Ther 317: 97-108, 2006.
    • (2006) J Pharmacol Exp Ther , vol.317 , pp. 97-108
    • Guo, M.1    Roman, R.J.2    Fenstermacher, J.D.3    Brown, S.L.4    Falck, J.R.5    Arbab, A.S.6    Edwards, P.A.7    Scicli, A.G.8
  • 7
    • 71949116212 scopus 로고    scopus 로고
    • Down-regulation of 20-HETE synthesis and signaling inhibits renal adenocarcinoma cell proliferation and tumor growth
    • Alexanian A, Rufanova VA, Miller B, Flasch A, Roman RJ, and Sorokin A: Down-regulation of 20-HETE synthesis and signaling inhibits renal adenocarcinoma cell proliferation and tumor growth. Anticancer Res 29: 3819-3824, 2009.
    • (2009) Anticancer Res , vol.29 , pp. 3819-3824
    • Alexanian, A.1    Rufanova, V.A.2    Miller, B.3    Flasch, A.4    Roman, R.J.5    Sorokin, A.6
  • 8
    • 27744551500 scopus 로고    scopus 로고
    • Role of 20-hydroxyeicosatetraenoic acid (20-HETE) in vascular system
    • DOI 10.1540/jsmr.41.175
    • Miyata N and Roman RJ: Role of 20-hydroxyeicosatetraenoic acid (20-HETE) in vascular system. J Smooth Muscle Res 41: 175-193, 2005. (Pubitemid 41596358)
    • (2005) Journal of Smooth Muscle Research , vol.41 , Issue.4 , pp. 175-193
    • Miyata, N.1    Roman, R.J.2
  • 10
    • 24944511513 scopus 로고    scopus 로고
    • Cytochrome P450 4A isoform inhibitory profile of N-hydroxy-N′-(4- butyl-2-methylphenyl)-formamidine (HET0016), a selective inhibitor of 20-HETE synthesis
    • DOI 10.1248/bpb.28.1651
    • Seki T, Wang MH, Miyata N and Laniado-Schwartzman M: Cytochrome P450 4A isoform inhibitory profile of N-hydroxy-N′-(4-butyl-2-methylphenyl)- formamidine (HET0016), a selective inhibitor of 20-HETE synthesis. Biol Pharm Bull 28: 1651-1654, 2005. (Pubitemid 41324126)
    • (2005) Biological and Pharmaceutical Bulletin , vol.28 , Issue.9 , pp. 1651-1654
    • Seki, T.1    Wang, M.-H.2    Miyata, N.3    Laniado-Schwartzman, M.4
  • 11
    • 27144552930 scopus 로고    scopus 로고
    • Human U251 glioma cell proliferation is suppressed by HET0016 [N-hydroxy-N′-(4-butyl-2-methylphenyl)formamidine], a selective inhibitor of CYP4A
    • DOI 10.1124/jpet.105.088567
    • Guo M, Roman RJ, Falck JR, Edwards PA and Scicli AG: Human U251 glioma cell proliferation is suppressed by HET0016 [N-hydroxy-N′-(4-butyl-2- methylphenyl)formamidine], a selective inhibitor of CYP4A. J Pharmacol Exp Ther 315: 526-533, 2005. (Pubitemid 41500716)
    • (2005) Journal of Pharmacology and Experimental Therapeutics , vol.315 , Issue.2 , pp. 526-533
    • Guo, M.1    Roman, R.J.2    Falck, J.R.3    Edwards, P.A.4    Scicli, A.G.5
  • 14
    • 0031808169 scopus 로고    scopus 로고
    • Metabolism of arachidonic acid to 20-hydroxy-5,8,11,14-eicosatetraenoic acid by P450 enzymes in human liver: Involvement of CYP4F2 and CYP4A11
    • Powell PK, Wolf I, Jin R and Lasker JM: Metabolism of arachidonic acid to 20-hydroxy-5,8,11, 14-eicosatetraenoic acid by P450 enzymes in human liver: involvement of CYP4F2 and CYP4A11. J Pharmacol Exp Ther 285: 1327-1336, 1998. (Pubitemid 28277936)
    • (1998) Journal of Pharmacology and Experimental Therapeutics , vol.285 , Issue.3 , pp. 1327-1336
    • Powell, P.K.1    Wolf, I.2    Jin, R.3    Lasker, J.M.4
  • 15
    • 38449095968 scopus 로고    scopus 로고
    • Measurement of eicosanoids in cancer tissues
    • Wang D and Dubois RN: Measurement of eicosanoids in cancer tissues. Methods Enzymol 433: 27-50, 2007.
    • (2007) Methods Enzymol , vol.433 , pp. 27-50
    • Wang, D.1    Dubois, R.N.2
  • 16
    • 0033668698 scopus 로고    scopus 로고
    • The role of cytochrome P450 in tumour development and progression and its potential in therapy
    • Murray GI: The role of cytochrome P450 in tumour development and progression and its potential in therapy. J Pathol 192: 419-426, 2000.
    • (2000) J Pathol , vol.192 , pp. 419-426
    • Murray, G.I.1
  • 17
    • 69449101237 scopus 로고    scopus 로고
    • 20-HETE activates the Raf/MEK/ERK pathway in renal epithelial cells through an EGFR-and c-Src-dependent mechanism
    • Akbulut T, Regner KR, Roman RJ, Avner ED, Falck JR and Park F: 20-HETE activates the Raf/MEK/ERK pathway in renal epithelial cells through an EGFR-and c-Src-dependent mechanism. Am J Physiol Renal Physiol 297: F662-F670, 2009.
    • (2009) Am J Physiol Renal Physiol , vol.297
    • Akbulut, T.1    Regner, K.R.2    Roman, R.J.3    Avner, E.D.4    Falck, J.R.5    Park, F.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.