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Volumn 94, Issue 4, 2004, Pages 534-541

Interleukin-6 Induces Oxidative Stress and Endothehal Dysfunction by Overexpression of the Angiotensin II Type 1 Receptor

Author keywords

AT1 receptor; Endothelial dysfunction; Inflammation; Interleukin 6; Oxidative stress

Indexed keywords

ANGIOTENSIN 1 RECEPTOR; INTERLEUKIN 6; MESSENGER RNA; REACTIVE OXYGEN METABOLITE; RECOMBINANT INTERLEUKIN 6;

EID: 1542313876     PISSN: 00097330     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.RES.0000115557.25127.8D     Document Type: Article
Times cited : (398)

References (43)
  • 1
    • 0037022910 scopus 로고    scopus 로고
    • Inflammation and atherosclerosis
    • Libby P, Ridker PM, Maseri A. Inflammation and atherosclerosis. Circulation. 2002;105:1135-1143.
    • (2002) Circulation , vol.105 , pp. 1135-1143
    • Libby, P.1    Ridker, P.M.2    Maseri, A.3
  • 2
    • 0033552883 scopus 로고    scopus 로고
    • Atherosclerosis: An inflammatory disease
    • Ross R. Atherosclerosis: an inflammatory disease. N Engl J Med. 1999;340:115-126.
    • (1999) N Engl J Med , vol.340 , pp. 115-126
    • Ross, R.1
  • 4
    • 0037031310 scopus 로고    scopus 로고
    • Endothelial function: A barometer for cardiovascular risk?
    • Vita JA, Keaney JF. Endothelial function: a barometer for cardiovascular risk? Circulation. 2002;106:640-642.
    • (2002) Circulation , vol.106 , pp. 640-642
    • Vita, J.A.1    Keaney, J.F.2
  • 6
    • 0342424181 scopus 로고    scopus 로고
    • Prognostic impact of coronary vasodilator dysfunction on adverse long-term outcome of coronary heart disease
    • Schächinger V, Britten MB, Zeiher AM. Prognostic impact of coronary vasodilator dysfunction on adverse long-term outcome of coronary heart disease. Circulation. 2000;101:1899-1906.
    • (2000) Circulation , vol.101 , pp. 1899-1906
    • Schächinger, V.1    Britten, M.B.2    Zeiher, A.M.3
  • 8
  • 9
    • 0032572719 scopus 로고    scopus 로고
    • -/- mice reveals a role for chemokines in the initiation of atherosclerosis
    • -/- mice reveals a role for chemokines in the initiation of atherosclerosis. Nature. 1998;294:894-897.
    • (1998) Nature , vol.294 , pp. 894-897
    • Boring, L.1    Gosling, J.2    Cleary, M.3    Charo, E.F.4
  • 10
    • 0034681920 scopus 로고    scopus 로고
    • Plasma concentration of interleukin-6 and the risk of future myocardial infarction among apparently healthy men
    • Ridker PM, Rifai N, Stampfer MJ, Hennekens CH. Plasma concentration of interleukin-6 and the risk of future myocardial infarction among apparently healthy men. Circulation. 2000;101:1767-1772.
    • (2000) Circulation , vol.101 , pp. 1767-1772
    • Ridker, P.M.1    Rifai, N.2    Stampfer, M.J.3    Hennekens, C.H.4
  • 11
    • 0037154324 scopus 로고    scopus 로고
    • The AT1-type angiotensin receptor in oxidative stress and atherogenesis, part I: Oxidative stress and atherogenesis
    • Nickenig G, Harrison DG. The AT1-type angiotensin receptor in oxidative stress and atherogenesis, part I: oxidative stress and atherogenesis. Circulation. 2002;105:393-396.
    • (2002) Circulation , vol.105 , pp. 393-396
    • Nickenig, G.1    Harrison, D.G.2
  • 12
    • 0037192344 scopus 로고    scopus 로고
    • The AT1-type angiotensin receptor in oxidative stress and atherogenesis, part II: AT1 receptor regulation
    • Nickenig G, Harrison DG. The AT1-type angiotensin receptor in oxidative stress and atherogenesis, part II: AT1 receptor regulation. Circulation. 2002;105:530-536.
    • (2002) Circulation , vol.105 , pp. 530-536
    • Nickenig, G.1    Harrison, D.G.2
  • 13
    • 0033515524 scopus 로고    scopus 로고
    • Angiotensin II induces IL-6 transcription in vascular smooth muscle cells through pleiotropic activation of NF-κB transcription factors
    • Han Y, Runge MS, Brasier AR. Angiotensin II induces IL-6 transcription in vascular smooth muscle cells through pleiotropic activation of NF-κB transcription factors. Circ Res. 1999;84:695-703.
    • (1999) Circ Res , vol.84 , pp. 695-703
    • Han, Y.1    Runge, M.S.2    Brasier, A.R.3
  • 16
    • 0032811794 scopus 로고    scopus 로고
    • Induction of interleukin-6 expression by angiotensin II in rat vascular smooth muscle cells
    • Funakoshi Y, Ichiki T, Ito K, Takeshita A. Induction of interleukin-6 expression by angiotensin II in rat vascular smooth muscle cells. Hypertension. 1999;34:118-125.
    • (1999) Hypertension , vol.34 , pp. 118-125
    • Funakoshi, Y.1    Ichiki, T.2    Ito, K.3    Takeshita, A.4
  • 17
    • 0035122832 scopus 로고    scopus 로고
    • Inhibition of geranylgeranylation reduces angiotensin II-mediated free radical production in vascular smooth muscle cells: Involvement of angiotensin AT1 receptor expression and rac1 GTPase
    • Wassmann S, Laufs U, Bäumer AT, Müller K, Konkol C, Sauer H, Böhm M, Nickenig G. Inhibition of geranylgeranylation reduces angiotensin II-mediated free radical production in vascular smooth muscle cells: involvement of angiotensin AT1 receptor expression and rac1 GTPase. Mol Pharmacol. 2001;59:646-654.
    • (2001) Mol Pharmacol , vol.59 , pp. 646-654
    • Wassmann, S.1    Laufs, U.2    Bäumer, A.T.3    Müller, K.4    Konkol, C.5    Sauer, H.6    Böhm, M.7    Nickenig, G.8
  • 20
    • 0035569562 scopus 로고    scopus 로고
    • HMG-CoA reductase inhibitors improve endothelial dysfunction in normocholesterolemic hypertension via reduced production of reactive oxygen species
    • Wassmann S, Laufs U, Bäumer AT, Müller K, Ahlbory K, Linz W, Itter G, Rösen R, Böhm M, Nickenig G. HMG-CoA reductase inhibitors improve endothelial dysfunction in normocholesterolemic hypertension via reduced production of reactive oxygen species. Hypertension. 2001;37:1450-1457.
    • (2001) Hypertension , vol.37 , pp. 1450-1457
    • Wassmann, S.1    Laufs, U.2    Bäumer, A.T.3    Müller, K.4    Ahlbory, K.5    Linz, W.6    Itter, G.7    Rösen, R.8    Böhm, M.9    Nickenig, G.10
  • 21
    • 0033401784 scopus 로고    scopus 로고
    • Sensitive superoxide detection in vascular cells by the new chemiluminescence dye L-012
    • Sohn HY, Gloe T, Keller M, Schoenafinger K, Pohl U. Sensitive superoxide detection in vascular cells by the new chemiluminescence dye L-012. J Vasc Res. 1999;36:456-464.
    • (1999) J Vasc Res , vol.36 , pp. 456-464
    • Sohn, H.Y.1    Gloe, T.2    Keller, M.3    Schoenafinger, K.4    Pohl, U.5
  • 22
    • 0030017431 scopus 로고    scopus 로고
    • RNA polymerase II inhibitor, 5,6-dichloro-1-β -D-ribofuranosylbenzimidazole (DRB), causes erythroleukemic differentiation and transcriptional activation of erythroid genes
    • Hensold JO, Barth D, Stratton CA. RNA polymerase II inhibitor, 5,6-dichloro-1-β-D-ribofuranosylbenzimidazole (DRB), causes erythroleukemic differentiation and transcriptional activation of erythroid genes. J Cell Physiol. 1996;168:105-113.
    • (1996) J Cell Physiol , vol.168 , pp. 105-113
    • Hensold, J.O.1    Barth, D.2    Stratton, C.A.3
  • 23
    • 0035960677 scopus 로고    scopus 로고
    • Endothelial dysfunction, oxidative stress, and risk of cardiovascular events in patients with coronary artery disease
    • Heitzer T, Schlinzig T, Krohn K, Meinertz T, Münzel T. Endothelial dysfunction, oxidative stress, and risk of cardiovascular events in patients with coronary artery disease. Circulation. 2001;104:2673-2678.
    • (2001) Circulation , vol.104 , pp. 2673-2678
    • Heitzer, T.1    Schlinzig, T.2    Krohn, K.3    Meinertz, T.4    Münzel, T.5
  • 24
    • 0034634281 scopus 로고    scopus 로고
    • Endothelial dysfunction in cardiovascular diseases: The role of oxidant stress
    • Cai H, Harrison DG. Endothelial dysfunction in cardiovascular diseases: the role of oxidant stress. Circ Res. 2000;87:840-844.
    • (2000) Circ Res , vol.87 , pp. 840-844
    • Cai, H.1    Harrison, D.G.2
  • 25
    • 0037230927 scopus 로고    scopus 로고
    • Interrelationship of free oxygen radicals and endothelial dysfunction: Modulation by statins
    • Wassmann S, Nickenig G. Interrelationship of free oxygen radicals and endothelial dysfunction: modulation by statins. Endothelium. 2003;10:23-33.
    • (2003) Endothelium , vol.10 , pp. 23-33
    • Wassmann, S.1    Nickenig, G.2
  • 26
    • 0037178764 scopus 로고    scopus 로고
    • Withdrawal of 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors elicits oxidative stress and induces endothelial dysfunction mice
    • Vecchione C, Brandes RP. Withdrawal of 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors elicits oxidative stress and induces endothelial dysfunction mice. Circ Res. 2002;91:173-179.
    • (2002) Circ Res , vol.91 , pp. 173-179
    • Vecchione, C.1    Brandes, R.P.2
  • 27
    • 0344193110 scopus 로고    scopus 로고
    • Insulin induces upregulation of vascular AT1 receptor gene expression by posttranscriptional mechanisms
    • Nickenig G, Röling J, Strehlow K, Schnabel P, Böhm M. Insulin induces upregulation of vascular AT1 receptor gene expression by posttranscriptional mechanisms. Circulation. 1998;98:2453-2460.
    • (1998) Circulation , vol.98 , pp. 2453-2460
    • Nickenig, G.1    Röling, J.2    Strehlow, K.3    Schnabel, P.4    Böhm, M.5
  • 28
    • 0028817924 scopus 로고
    • Angiotensin II down-regulates the vascular smooth muscle AT1 receptor by transcriptional and posttranscriptional mechanisms: Evidence for homologous and heterologous regulation
    • Lassegue B, Alexander RW, Nickenig G, Clark M, Murphy TJ, Griendling KK. Angiotensin II down-regulates the vascular smooth muscle AT1 receptor by transcriptional and posttranscriptional mechanisms: evidence for homologous and heterologous regulation. Mol Pharmacol. 1995;48:601-609.
    • (1995) Mol Pharmacol , vol.48 , pp. 601-609
    • Lassegue, B.1    Alexander, R.W.2    Nickenig, G.3    Clark, M.4    Murphy, T.J.5    Griendling, K.K.6
  • 30
    • 0031023734 scopus 로고    scopus 로고
    • Upregulation of vascular angiotensin II receptor gene expression by low density lipoprotein in vascular smooth muscle cells
    • Nickenig G, Sachinidis A, Michaelsen F, Böhm M, Seewald S, Vetter H. Upregulation of vascular angiotensin II receptor gene expression by low density lipoprotein in vascular smooth muscle cells. Circulation. 1997;95:473-478.
    • (1997) Circulation , vol.95 , pp. 473-478
    • Nickenig, G.1    Sachinidis, A.2    Michaelsen, F.3    Böhm, M.4    Seewald, S.5    Vetter, H.6
  • 31
    • 0034633808 scopus 로고    scopus 로고
    • Differential effects of estrogen and progesterone on AT1 receptor gene expression in vascular smooth muscle cells
    • Nickenig G, Strehlow K, Wassmann S, Bäumer AT, Ahlbory K, Sauer H, Böhm M. Differential effects of estrogen and progesterone on AT1 receptor gene expression in vascular smooth muscle cells. Circulation. 2000;102:1828-1833.
    • (2000) Circulation , vol.102 , pp. 1828-1833
    • Nickenig, G.1    Strehlow, K.2    Wassmann, S.3    Bäumer, A.T.4    Ahlbory, K.5    Sauer, H.6    Böhm, M.7
  • 32
    • 0028149736 scopus 로고
    • Down-regulation by growth factors of vascular smooth muscle angiotensin receptor gene expression
    • Nickenig G, Murphy TJ. Down-regulation by growth factors of vascular smooth muscle angiotensin receptor gene expression. Mol Pharmacol. 1994;46:653-659.
    • (1994) Mol Pharmacol , vol.46 , pp. 653-659
    • Nickenig, G.1    Murphy, T.J.2
  • 34
    • 0034603775 scopus 로고    scopus 로고
    • Inhibition of early atherogenesis by losartan in monkeys with diet-induced hypercholesterolemia
    • Strawn WB, Chapell MC, Dean RH, Kivlighn S, Ferrario CM. Inhibition of early atherogenesis by losartan in monkeys with diet-induced hypercholesterolemia. Circulation. 2000;101:1586-1593.
    • (2000) Circulation , vol.101 , pp. 1586-1593
    • Strawn, W.B.1    Chapell, M.C.2    Dean, R.H.3    Kivlighn, S.4    Ferrario, C.M.5
  • 37
    • 0034636121 scopus 로고    scopus 로고
    • Correction of arterial structure and endothelial dysfunction in human essential hypertension by the angiotensin receptor antagonist losartan
    • Schiffrin EL, Park JB, Intengan HD, Touyz R. Correction of arterial structure and endothelial dysfunction in human essential hypertension by the angiotensin receptor antagonist losartan. Circulation. 2000;101:1653-1659.
    • (2000) Circulation , vol.101 , pp. 1653-1659
    • Schiffrin, E.L.1    Park, J.B.2    Intengan, H.D.3    Touyz, R.4
  • 38
    • 0027423378 scopus 로고
    • Effect of ramipril on mortality and morbidity of survivors of acute myocardial infarction with clinical evidence of heart failure
    • Acute Infarction Ramipril Efficacy (AIRE) Study Investigators. Effect of ramipril on mortality and morbidity of survivors of acute myocardial infarction with clinical evidence of heart failure. Lancet. 1993;342:821-828.
    • (1993) Lancet , vol.342 , pp. 821-828
  • 39
    • 0034688194 scopus 로고    scopus 로고
    • Effects of an angiotensin-converting-enzyme, ramipril, on cardiovascular events
    • Heart Outcome Prevention Evaluation Study Investigators. Effects of an angiotensin-converting-enzyme, ramipril, on cardiovascular events. N Engl J Med. 2000;342:145-153.
    • (2000) N Engl J Med , vol.342 , pp. 145-153
  • 40
    • 0023266532 scopus 로고
    • Effects of enalapriI on mortality in severe congestive heart failure: Results of the Cooperative North Scandinavian Enalapril Survival Study (Consensus)
    • Consensus Trial Study Group. Effects of enalapriI on mortality in severe congestive heart failure: results of the Cooperative North Scandinavian Enalapril Survival Study (Consensus). N Engl J Med. 1987;316:1429-1435.
    • (1987) N Engl J Med , vol.316 , pp. 1429-1435


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