A single nucleotide polymorphism in the CYP4F2 but not CYP4A11 gene is associated with increased 20-HETE excretion and blood pressure

Hypertension

Volumn 51, Issue 5, 2008, Pages 1393-1398

  Ward, Natalie C ^a,c   Tsai, I Jung ^a   Barden, Anne ^a   Van Bockxmeer, Frank M ^b   Puddey, Ian B ^a   Hodgson, Jonathan M ^a   Croft, Kevin D ^a  

^a UNIVERSITY OF WESTERN AUSTRALIA   (Australia)

^b UNIVERSITY OF WESTERN AUSTRALIA   (Australia)

^c UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL   (United States)

Author keywords

20 HETE; Blood pressure; CYP4A11 F434S; CYP4F2 V433M; Cytochrome P450

Indexed keywords

20 HYDROXYICOSATETRAENOIC ACID; CYTOCHROME P450; CYTOCHROME P450 4A11; CYTOCHROME P450 4F2; UNCLASSIFIED DRUG;

ADULT; ALLELE; ARTICLE; CONTROLLED STUDY; FEMALE; GENE MUTATION; GENETIC ASSOCIATION; GENETIC VARIABILITY; HETEROZYGOTE; HOMOZYGOSITY; HUMAN; HYPERTENSION; LINEAR REGRESSION ANALYSIS; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; SINGLE NUCLEOTIDE POLYMORPHISM; SYSTOLIC BLOOD PRESSURE; URINARY EXCRETION;

AGED; ALLELES; BLOOD PRESSURE; CYTOCHROME P-450 ENZYME SYSTEM; FEMALE; GENOTYPE; HUMANS; HYDROXYEICOSATETRAENOIC ACIDS; HYPERTENSION; MALE; MIDDLE AGED; MUTATION; POLYMORPHISM, SINGLE NUCLEOTIDE; REGRESSION ANALYSIS;

EID: 42349090786     PISSN: 0194911X     EISSN: None     Source Type: Journal    
DOI: 10.1161/HYPERTENSIONAHA.107.104463     Document Type: Article

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