Wnt signaling directs a metabolic program of glycolysis and angiogenesis in colon cancer

EMBO Journal

Volumn 33, Issue 13, 2014, Pages 1454-1473

  Pate, Kira T ^a   Stringari, Chiara ^b,d   Sprowl Tanio, Stephanie ^a   Wang, Kehui ^a   Teslaa, Tara ^c   Hoverter, Nate P ^a   McQuade, Miriam M ^a   Garner, Chad ^a   Digman, Michelle A ^b   Teitell, Michael A ^c   Edwards, Robert A ^a   Gratton, Enrico ^b   Waterman, Marian L ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b University of California at Irvine   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d LABORATOIRE D OPTIQUE ET BIOSCIENCES   (France)

Author keywords

angiogenesis; colon cancer; fluorescence lifetime imaging; metabolism; Wnt

Indexed keywords

BETA CATENIN; DOXYCYCLINE; PHOSPHOINOSITIDE DEPENDENT PROTEIN KINASE 1; PYRUVATE DEHYDROGENASE KINASE; PYRUVATE DEHYDROGENASE KINASE 1; UNCLASSIFIED DRUG;

ANGIOGENESIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CANCER CELL; CELL METABOLISM; CELL PROLIFERATION; CHROMATIN IMMUNOPRECIPITATION; COLON CANCER; CONTROLLED STUDY; FLUORESCENCE LIFETIME IMAGING MICROSCOPY; FLUORESCENCE MICROSCOPY; GENE EXPRESSION; GENE OVEREXPRESSION; GLUCOSE INTAKE; GLYCOLYSIS; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; IN VIVO STUDY; MITOCHONDRIAL RESPIRATION; MOUSE; NONHUMAN; OXIDATIVE PHOSPHORYLATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TUMOR GROWTH; TUMOR MICROENVIRONMENT; TUMOR XENOGRAFT; WNT SIGNALING PATHWAY;

ANGIOGENESIS; COLON CANCER; FLUORESCENCE LIFETIME IMAGING; METABOLISM; WNT;

ANIMALS; CELL LINE, TUMOR; COLONIC NEOPLASMS; GLUCOSE; GLYCOLYSIS; HUMANS; MICE; MITOCHONDRIA; NEOPLASM PROTEINS; NEOVASCULARIZATION, PATHOLOGIC; OXYGEN CONSUMPTION; PROTEIN-SERINE-THREONINE KINASES; TUMOR MICROENVIRONMENT; WNT SIGNALING PATHWAY;

EID: 84903702539     PISSN: 02614189     EISSN: 14602075     Source Type: Journal    
DOI: 10.15252/embj.201488598     Document Type: Article

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