Conserved modular domains team up to latch-open active protein kinase Cα

Journal of Biological Chemistry

Volumn 289, Issue 25, 2014, Pages 17812-17829

  Swanson, Carter J ^a   Ritt, Michael ^b   Wang, William ^b   Lang, Michael J ^b   Narayan, Arvind ^a   Tesmer, John J ^a   Westfall, Margaret ^a,b   Sivaramakrishnan, Sivaraj ^a,b  

^a UNIVERSITY OF MICHIGAN   (United States)

^b UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ENZYMES;

CONTEXT DEPENDENT; DOMAIN INTERACTIONS; INTERMOLECULAR INTERACTIONS; INTRAMOLECULAR INTERACTIONS; MEMBRANE LOCALIZATION; NANOMOLAR AFFINITY; REGULATORY MECHANISM; SIGNALING PROTEINS;

CELL SIGNALING;

HOMODIMER; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PROTEIN KINASE C ALPHA;

ANIMAL CELL; ARTICLE; BINDING AFFINITY; CELL FUNCTION; CONTROLLED STUDY; DIMERIZATION; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME LOCALIZATION; ENZYME PHOSPHORYLATION; HOMEOSTASIS; HOMODIMERIZATION; IN VITRO STUDY; INTRACELLULAR SIGNALING; MOLECULAR INTERACTION; MOLECULAR RECOGNITION; NONHUMAN; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN DEPLETION; PROTEIN DOMAIN; PROTEIN MOTIF; PROTEIN STABILITY; REGULATORY MECHANISM;

EXTRACELLULAR SIGNAL-REGULATED KINASE (ERK); FLUORESCENCE RESONANCE ENERGY TRANSFER (FRET); HOMODIMERIZATION; MODULAR DOMAINS; PKC; PROTEIN DOMAIN; PROTEIN KINASE C (PKC); PROTEIN-PROTEIN INTERACTION;

ANIMALS; CELL MEMBRANE; CHO CELLS; CRICETINAE; CRICETULUS; HUMANS; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; PROTEIN KINASE C-ALPHA; PROTEIN MULTIMERIZATION; PROTEIN STRUCTURE, TERTIARY; SIGNAL TRANSDUCTION;

EID: 84903462238     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M113.534750     Document Type: Article

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