Allosteric regulation of protein kinase PKCζ by the N-terminal C1 domain and small compounds to the PIF-pocket

Chemistry and Biology

Volumn 18, Issue 11, 2011, Pages 1463-1473

  Lopez Garcia, Laura A ^a   Schulze, Jörg O ^a   Fröhner, Wolfgang ^b   Zhang, Hua ^a   Süß, Evelyn ^a   Weber, Nadja ^b   Navratil, Jeanette ^a   Amon, Sabine ^c   Hindie, Valerie ^a,e   Zeuzem, Stefan ^a   Jørgensen, Thomas J D ^c   Alzari, Pedro M ^d   Neimanis, Sonja ^a   Engel, Matthias ^b   Biondi, Ricardo M ^a  

^a UNIVERSITY HOSPITAL FRANKFURT   (Germany)

^b SAARLAND UNIVERSITY   (Germany)

^c UNIVERSITY OF SOUTHERN DENMARK   (Denmark)

^d INSTITUT PASTEUR   (France)

^e Hybrigenics SA   (France)

Author keywords

[No Author keywords available]

Indexed keywords

IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; PROTEIN KINASE C; PROTEIN KINASE C ZETA;

ALLOSTERISM; ARTICLE; BINDING SITE; BIOCATALYSIS; CHEMISTRY; DRUG EFFECT; HUMAN; METABOLISM; MOLECULAR LIBRARY; PROTEIN TERTIARY STRUCTURE; SIGNAL TRANSDUCTION; TUMOR CELL LINE;

ALLOSTERIC REGULATION; BINDING SITES; BIOCATALYSIS; CELL LINE, TUMOR; HUMANS; NF-KAPPA B; PROTEIN KINASE C; PROTEIN STRUCTURE, TERTIARY; SIGNAL TRANSDUCTION; SMALL MOLECULE LIBRARIES;

EID: 80053904856     PISSN: 10745521     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.chembiol.2011.08.010     Document Type: Article

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