-
1
-
-
44649184557
-
A redox-dependent pathway for regulating class II HDACs and cardiac hypertrophy
-
T. Ago, T. Liu, P. Zhai, W. Chen, H. Li, and J.D. Molkentin et al. A redox-dependent pathway for regulating class II HDACs and cardiac hypertrophy Cell 133 2008 978 993
-
(2008)
Cell
, vol.133
, pp. 978-993
-
-
Ago, T.1
Liu, T.2
Zhai, P.3
Chen, W.4
Li, H.5
Molkentin, J.D.6
-
2
-
-
84879518259
-
Trichostatin A, an HDAC class I/II inhibitor, promotes pi-induced vascular calcification via up-regulation of the expression of alkaline phosphatase
-
T. Azechi, D. Kanehira, T. Kobayashi, R. Sudo, A. Nishimura, and F. Sato et al. Trichostatin A, an HDAC class I/II inhibitor, promotes pi-induced vascular calcification via up-regulation of the expression of alkaline phosphatase J Atheroscler Thromb 20 2013 538 547
-
(2013)
J Atheroscler Thromb
, vol.20
, pp. 538-547
-
-
Azechi, T.1
Kanehira, D.2
Kobayashi, T.3
Sudo, R.4
Nishimura, A.5
Sato, F.6
-
3
-
-
34249026300
-
High-resolution profiling of histone methylations in the human genome
-
A. Barski, S. Cuddapah, K. Cui, T.Y. Roh, D.E. Schones, and Z. Wang et al. High-resolution profiling of histone methylations in the human genome Cell 129 2007 823 837
-
(2007)
Cell
, vol.129
, pp. 823-837
-
-
Barski, A.1
Cuddapah, S.2
Cui, K.3
Roh, T.Y.4
Schones, D.E.5
Wang, Z.6
-
4
-
-
0027207242
-
Tumor necrosis factor and interleukin-1 lead to phosphorylation and loss of i kappa B alpha: A mechanism for NF-kappa B activation
-
A.A. Beg, T.S. Finco, P.V. Nantermet, and A.S. Baldwin Jr. Tumor necrosis factor and interleukin-1 lead to phosphorylation and loss of I kappa B alpha: a mechanism for NF-kappa B activation Mol Cell Biol 13 1993 3301 3310
-
(1993)
Mol Cell Biol
, vol.13
, pp. 3301-3310
-
-
Beg, A.A.1
Finco, T.S.2
Nantermet, P.V.3
Baldwin, Jr.A.S.4
-
5
-
-
78650121847
-
Molecular distinction between physiological and pathological cardiac hypertrophy: Experimental findings and therapeutic strategies
-
B.C. Bernardo, K.L. Weeks, L. Pretorius, and J.R. McMullen Molecular distinction between physiological and pathological cardiac hypertrophy: experimental findings and therapeutic strategies Pharmacol Ther 128 2010 191 227
-
(2010)
Pharmacol Ther
, vol.128
, pp. 191-227
-
-
Bernardo, B.C.1
Weeks, K.L.2
Pretorius, L.3
McMullen, J.R.4
-
6
-
-
3943054839
-
The Sir2 family of protein deacetylases
-
G. Blander, and L. Guarente The Sir2 family of protein deacetylases Annu Rev Biochem 73 2004 417 435
-
(2004)
Annu Rev Biochem
, vol.73
, pp. 417-435
-
-
Blander, G.1
Guarente, L.2
-
7
-
-
79956200230
-
Suppression of histone deacetylases worsens right ventricular dysfunction after pulmonary artery banding in rats
-
H.J. Bogaard, S. Mizuno, A.A. Hussaini, S. Toldo, A. Abbate, and D. Kraskauskas et al. Suppression of histone deacetylases worsens right ventricular dysfunction after pulmonary artery banding in rats Am J Respir Crit Care Med 183 2011 1402 1410
-
(2011)
Am J Respir Crit Care Med
, vol.183
, pp. 1402-1410
-
-
Bogaard, H.J.1
Mizuno, S.2
Hussaini, A.A.3
Toldo, S.4
Abbate, A.5
Kraskauskas, D.6
-
8
-
-
41449118488
-
Ca2+/calmodulin-dependent protein kinase IIdelta and protein kinase D overexpression reinforce the histone deacetylase 5 redistribution in heart failure
-
J. Bossuyt, K. Helmstadter, X. Wu, H. Clements-Jewery, R.S. Haworth, and M. Avkiran et al. Ca2+/calmodulin-dependent protein kinase IIdelta and protein kinase D overexpression reinforce the histone deacetylase 5 redistribution in heart failure Circ Res 102 2008 695 702
-
(2008)
Circ Res
, vol.102
, pp. 695-702
-
-
Bossuyt, J.1
Helmstadter, K.2
Wu, X.3
Clements-Jewery, H.4
Haworth, R.S.5
Avkiran, M.6
-
9
-
-
84867426439
-
Dynamically regulated sumoylation of HDAC2 controls p53 deacetylation and restricts apoptosis following genotoxic stress
-
A. Brandl, T. Wagner, K.M. Uhlig, S.K. Knauer, R.H. Stauber, and F. Melchior et al. Dynamically regulated sumoylation of HDAC2 controls p53 deacetylation and restricts apoptosis following genotoxic stress J Mol Cell Biol 4 2012 284 293
-
(2012)
J Mol Cell Biol
, vol.4
, pp. 284-293
-
-
Brandl, A.1
Wagner, T.2
Uhlig, K.M.3
Knauer, S.K.4
Stauber, R.H.5
Melchior, F.6
-
10
-
-
67650418364
-
Targeting histone deacetylases for heart failure
-
E.W. Bush, and T.A. McKinsey Targeting histone deacetylases for heart failure Expert Opin Ther Targets 13 2009 767 784
-
(2009)
Expert Opin Ther Targets
, vol.13
, pp. 767-784
-
-
Bush, E.W.1
McKinsey, T.A.2
-
11
-
-
84863231352
-
Selective class i histone deacetylase inhibition suppresses hypoxia-induced cardiopulmonary remodeling through an antiproliferative mechanism
-
M.A. Cavasin, K. Demos-Davies, T.R. Horn, L.A. Walker, D.D. Lemon, and N. Birdsey et al. Selective class I histone deacetylase inhibition suppresses hypoxia-induced cardiopulmonary remodeling through an antiproliferative mechanism Circ Res 110 2012 739 748
-
(2012)
Circ Res
, vol.110
, pp. 739-748
-
-
Cavasin, M.A.1
Demos-Davies, K.2
Horn, T.R.3
Walker, L.A.4
Lemon, D.D.5
Birdsey, N.6
-
12
-
-
84872055680
-
Acute beta-adrenergic activation triggers nuclear import of histone deacetylase 5 and delays G(q)-induced transcriptional activation
-
C.W. Chang, L. Lee, D. Yu, K. Dao, J. Bossuyt, and D.M. Bers Acute beta-adrenergic activation triggers nuclear import of histone deacetylase 5 and delays G(q)-induced transcriptional activation J Biol Chem 288 2013 192 204
-
(2013)
J Biol Chem
, vol.288
, pp. 192-204
-
-
Chang, C.W.1
Lee, L.2
Yu, D.3
Dao, K.4
Bossuyt, J.5
Bers, D.M.6
-
13
-
-
4544358659
-
Histone deacetylases 5 and 9 govern responsiveness of the heart to a subset of stress signals and play redundant roles in heart development
-
S. Chang, T.A. McKinsey, C.L. Zhang, J.A. Richardson, J.A. Hill, and E.N. Olson Histone deacetylases 5 and 9 govern responsiveness of the heart to a subset of stress signals and play redundant roles in heart development Mol Cell Biol 24 2004 8467 8476
-
(2004)
Mol Cell Biol
, vol.24
, pp. 8467-8476
-
-
Chang, S.1
McKinsey, T.A.2
Zhang, C.L.3
Richardson, J.A.4
Hill, J.A.5
Olson, E.N.6
-
14
-
-
0037011056
-
Acetylation of RelA at discrete sites regulates distinct nuclear functions of NF-kappaB
-
L.F. Chen, Y. Mu, and W.C. Greene Acetylation of RelA at discrete sites regulates distinct nuclear functions of NF-kappaB EMBO J 21 2002 6539 6548
-
(2002)
EMBO J
, vol.21
, pp. 6539-6548
-
-
Chen, L.F.1
Mu, Y.2
Greene, W.C.3
-
15
-
-
77950683482
-
Sodium valproate, a histone deacetylase inhibitor, but not captopril, prevents right ventricular hypertrophy in rats
-
Y.K. Cho, G.H. Eom, H.J. Kee, H.S. Kim, W.Y. Choi, and K.I. Nam et al. Sodium valproate, a histone deacetylase inhibitor, but not captopril, prevents right ventricular hypertrophy in rats Circ J 74 2010 760 770
-
(2010)
Circ J
, vol.74
, pp. 760-770
-
-
Cho, Y.K.1
Eom, G.H.2
Kee, H.J.3
Kim, H.S.4
Choi, W.Y.5
Nam, K.I.6
-
16
-
-
27644550272
-
Trichostatin A exacerbates atherosclerosis in low density lipoprotein receptor-deficient mice
-
J.H. Choi, K.H. Nam, J. Kim, M.W. Baek, J.E. Park, and H.Y. Park et al. Trichostatin A exacerbates atherosclerosis in low density lipoprotein receptor-deficient mice Arterioscler Thromb Vasc Biol 25 2005 2404 2409
-
(2005)
Arterioscler Thromb Vasc Biol
, vol.25
, pp. 2404-2409
-
-
Choi, J.H.1
Nam, K.H.2
Kim, J.3
Baek, M.W.4
Park, J.E.5
Park, H.Y.6
-
17
-
-
68949212379
-
Lysine acetylation targets protein complexes and co-regulates major cellular functions
-
C. Choudhary, C. Kumar, F. Gnad, M.L. Nielsen, M. Rehman, and T.C. Walther et al. Lysine acetylation targets protein complexes and co-regulates major cellular functions Science 325 2009 834 840
-
(2009)
Science
, vol.325
, pp. 834-840
-
-
Choudhary, C.1
Kumar, C.2
Gnad, F.3
Nielsen, M.L.4
Rehman, M.5
Walther, T.C.6
-
18
-
-
58049221125
-
HDAC2 blockade by nitric oxide and histone deacetylase inhibitors reveals a common target in Duchenne muscular dystrophy treatment
-
C. Colussi, C. Mozzetta, A. Gurtner, B. Illi, J. Rosati, and S. Straino et al. HDAC2 blockade by nitric oxide and histone deacetylase inhibitors reveals a common target in Duchenne muscular dystrophy treatment Proc Natl Acad Sci U S A 105 2008 19183 19187
-
(2008)
Proc Natl Acad Sci U S A
, vol.105
, pp. 19183-19187
-
-
Colussi, C.1
Mozzetta, C.2
Gurtner, A.3
Illi, B.4
Rosati, J.5
Straino, S.6
-
19
-
-
67650550793
-
Target gene specificity of USF-1 is directed via p38-mediated phosphorylation-dependent acetylation
-
S. Corre, A. Primot, Y. Baron, J. Le Seyec, C. Goding, and M.D. Galibert Target gene specificity of USF-1 is directed via p38-mediated phosphorylation-dependent acetylation J Biol Chem 284 2009 18851 18862
-
(2009)
J Biol Chem
, vol.284
, pp. 18851-18862
-
-
Corre, S.1
Primot, A.2
Baron, Y.3
Le Seyec, J.4
Goding, C.5
Galibert, M.D.6
-
20
-
-
0037452677
-
Regulation of peroxisome proliferator-activated receptor gamma coactivator 1 alpha (PGC-1 alpha) and mitochondrial function by MEF2 and HDAC5
-
M.P. Czubryt, J. McAnally, G.I. Fishman, and E.N. Olson Regulation of peroxisome proliferator-activated receptor gamma coactivator 1 alpha (PGC-1 alpha) and mitochondrial function by MEF2 and HDAC5 Proc Natl Acad Sci U S A 100 2003 1711 1716
-
(2003)
Proc Natl Acad Sci U S A
, vol.100
, pp. 1711-1716
-
-
Czubryt, M.P.1
McAnally, J.2
Fishman, G.I.3
Olson, E.N.4
-
21
-
-
0037189568
-
SUMO-1 modification of histone deacetylase 1 (HDAC1) modulates its biological activities
-
G. David, M.A. Neptune, and R.A. DePinho SUMO-1 modification of histone deacetylase 1 (HDAC1) modulates its biological activities J Biol Chem 277 2002 23658 23663
-
(2002)
J Biol Chem
, vol.277
, pp. 23658-23663
-
-
David, G.1
Neptune, M.A.2
Depinho, R.A.3
-
22
-
-
0037444803
-
Histone deacetylases (HDACs): Characterization of the classical HDAC family
-
A.J. de Ruijter, A.H. van Gennip, H.N. Caron, S. Kemp, and A.B. van Kuilenburg Histone deacetylases (HDACs): characterization of the classical HDAC family Biochem J 370 2003 737 749
-
(2003)
Biochem J
, vol.370
, pp. 737-749
-
-
De Ruijter, A.J.1
Van Gennip, A.H.2
Caron, H.N.3
Kemp, S.4
Van Kuilenburg, A.B.5
-
23
-
-
85047699941
-
Histone deacetylases inhibitors as anti-angiogenic agents altering vascular endothelial growth factor signaling
-
C.F. Deroanne, K. Bonjean, S. Servotte, L. Devy, A. Colige, and N. Clausse et al. Histone deacetylases inhibitors as anti-angiogenic agents altering vascular endothelial growth factor signaling Oncogene 21 2002 427 436
-
(2002)
Oncogene
, vol.21
, pp. 427-436
-
-
Deroanne, C.F.1
Bonjean, K.2
Servotte, S.3
Devy, L.4
Colige, A.5
Clausse, N.6
-
24
-
-
0033542476
-
Activation of nitric oxide synthase in endothelial cells by Akt-dependent phosphorylation
-
S. Dimmeler, I. Fleming, B. Fisslthaler, C. Hermann, R. Busse, and A.M. Zeiher Activation of nitric oxide synthase in endothelial cells by Akt-dependent phosphorylation Nature 399 1999 601 605
-
(1999)
Nature
, vol.399
, pp. 601-605
-
-
Dimmeler, S.1
Fleming, I.2
Fisslthaler, B.3
Hermann, C.4
Busse, R.5
Zeiher, A.M.6
-
25
-
-
34447509697
-
Vorinostat: A new oral histone deacetylase inhibitor approved for cutaneous T-cell lymphoma
-
M. Duvic, and J. Vu Vorinostat: a new oral histone deacetylase inhibitor approved for cutaneous T-cell lymphoma Expert Opin Investig Drugs 16 2007 1111 1120
-
(2007)
Expert Opin Investig Drugs
, vol.16
, pp. 1111-1120
-
-
Duvic, M.1
Vu, J.2
-
26
-
-
79958168664
-
Casein kinase-2alpha1 induces hypertrophic response by phosphorylation of histone deacetylase 2 S394 and its activation in the heart
-
G.H. Eom, Y.K. Cho, J.H. Ko, S. Shin, N. Choe, and Y. Kim et al. Casein kinase-2alpha1 induces hypertrophic response by phosphorylation of histone deacetylase 2 S394 and its activation in the heart Circulation 123 2011 2392 2403
-
(2011)
Circulation
, vol.123
, pp. 2392-2403
-
-
Eom, G.H.1
Cho, Y.K.2
Ko, J.H.3
Shin, S.4
Choe, N.5
Kim, Y.6
-
27
-
-
84897567792
-
Regulation of Acetylation of Histone Deacetylase 2 by p300/CBP-Associated Factor/Histone Deacetylase 5 in the Development of Cardiac Hypertrophy
-
[Epub ahead of print]
-
G.H. Eom, Y.S. Nam, J.G. Oh, N. Choe, H.K. Min, and E.K. Yoo et al. Regulation of Acetylation of Histone Deacetylase 2 by p300/CBP-Associated Factor/Histone Deacetylase 5 in the Development of Cardiac Hypertrophy Circ Res 114 2014 [Epub ahead of print]
-
(2014)
Circ Res
, vol.114
-
-
Eom, G.H.1
Nam, Y.S.2
Oh, J.G.3
Choe, N.4
Min, H.K.5
Yoo, E.K.6
-
28
-
-
36248983372
-
Kruppel-like factor 4 is acetylated by p300 and regulates gene transcription via modulation of histone acetylation
-
P.M. Evans, W. Zhang, X. Chen, J. Yang, K.K. Bhakat, and C. Liu Kruppel-like factor 4 is acetylated by p300 and regulates gene transcription via modulation of histone acetylation J Biol Chem 282 2007 33994 34002
-
(2007)
J Biol Chem
, vol.282
, pp. 33994-34002
-
-
Evans, P.M.1
Zhang, W.2
Chen, X.3
Yang, J.4
Bhakat, K.K.5
Liu, C.6
-
29
-
-
79953749086
-
Epigenetic regulation of vascular smooth muscle cell proliferation and neointima formation by histone deacetylase inhibition
-
H.M. Findeisen, F. Gizard, Y. Zhao, H. Qing, E.B. Heywood, and K.L. Jones et al. Epigenetic regulation of vascular smooth muscle cell proliferation and neointima formation by histone deacetylase inhibition Arterioscler Thromb Vasc Biol 31 2011 851 860
-
(2011)
Arterioscler Thromb Vasc Biol
, vol.31
, pp. 851-860
-
-
Findeisen, H.M.1
Gizard, F.2
Zhao, Y.3
Qing, H.4
Heywood, E.B.5
Jones, K.L.6
-
30
-
-
77953952667
-
Concept of vulnerable/unstable plaque
-
A.V. Finn, M. Nakano, J. Narula, F.D. Kolodgie, and R. Virmani Concept of vulnerable/unstable plaque Arterioscler Thromb Vasc Biol 30 2010 1282 1292
-
(2010)
Arterioscler Thromb Vasc Biol
, vol.30
, pp. 1282-1292
-
-
Finn, A.V.1
Nakano, M.2
Narula, J.3
Kolodgie, F.D.4
Virmani, R.5
-
31
-
-
18544387930
-
Isolation and characterization of a novel class II histone deacetylase, HDAC10
-
D.D. Fischer, R. Cai, U. Bhatia, F.A. Asselbergs, C. Song, and R. Terry et al. Isolation and characterization of a novel class II histone deacetylase, HDAC10 J Biol Chem 277 2002 6656 6666
-
(2002)
J Biol Chem
, vol.277
, pp. 6656-6666
-
-
Fischer, D.D.1
Cai, R.2
Bhatia, U.3
Asselbergs, F.A.4
Song, C.5
Terry, R.6
-
32
-
-
0036161439
-
Enzymatic activity associated with class II HDACs is dependent on a multiprotein complex containing HDAC3 and SMRT/N-CoR
-
W. Fischle, F. Dequiedt, M.J. Hendzel, M.G. Guenther, M.A. Lazar, and W. Voelter et al. Enzymatic activity associated with class II HDACs is dependent on a multiprotein complex containing HDAC3 and SMRT/N-CoR Mol Cell 9 2002 45 57
-
(2002)
Mol Cell
, vol.9
, pp. 45-57
-
-
Fischle, W.1
Dequiedt, F.2
Hendzel, M.J.3
Guenther, M.G.4
Lazar, M.A.5
Voelter, W.6
-
33
-
-
21644485961
-
The expression of endothelial nitric-oxide synthase is controlled by a cell-specific histone code
-
J.E. Fish, C.C. Matouk, A. Rachlis, S. Lin, S.C. Tai, and C. D'Abreo et al. The expression of endothelial nitric-oxide synthase is controlled by a cell-specific histone code J Biol Chem 280 2005 24824 24838
-
(2005)
J Biol Chem
, vol.280
, pp. 24824-24838
-
-
Fish, J.E.1
Matouk, C.C.2
Rachlis, A.3
Lin, S.4
Tai, S.C.5
D'Abreo, C.6
-
34
-
-
84858297477
-
Histone deacetylase 2 is upregulated in normal and keloid scars
-
E.J. Fitzgerald O'Connor, I.I. Badshah, L.Y. Addae, P. Kundasamy, S. Thanabalasingam, and D. Abioye et al. Histone deacetylase 2 is upregulated in normal and keloid scars J Invest Dermatol 132 2012 1293 1296
-
(2012)
J Invest Dermatol
, vol.132
, pp. 1293-1296
-
-
Fitzgerald O'Connor, E.J.1
Badshah, I.I.2
Addae, L.Y.3
Kundasamy, P.4
Thanabalasingam, S.5
Abioye, D.6
-
35
-
-
0013913467
-
Localization of atheroma: A theory based on boundary layer separation
-
J.A. Fox, and A.E. Hugh Localization of atheroma: a theory based on boundary layer separation Br Heart J 28 1966 388 399
-
(1966)
Br Heart J
, vol.28
, pp. 388-399
-
-
Fox, J.A.1
Hugh, A.E.2
-
36
-
-
0002537440
-
Cardiac hypertrophy: The good, the bad, and the ugly
-
N. Frey, and E.N. Olson Cardiac hypertrophy: the good, the bad, and the ugly Annu Rev Physiol 65 2003 45 79
-
(2003)
Annu Rev Physiol
, vol.65
, pp. 45-79
-
-
Frey, N.1
Olson, E.N.2
-
37
-
-
0036735385
-
FK228 (depsipeptide) as a natural prodrug that inhibits class i histone deacetylases
-
R. Furumai, A. Matsuyama, N. Kobashi, K.H. Lee, M. Nishiyama, and H. Nakajima et al. FK228 (depsipeptide) as a natural prodrug that inhibits class I histone deacetylases Cancer Res 62 2002 4916 4921
-
(2002)
Cancer Res
, vol.62
, pp. 4916-4921
-
-
Furumai, R.1
Matsuyama, A.2
Kobashi, N.3
Lee, K.H.4
Nishiyama, M.5
Nakajima, H.6
-
38
-
-
56549128210
-
Inhibition of class i histone deacetylase with an apicidin derivative prevents cardiac hypertrophy and failure
-
P. Gallo, M.V. Latronico, P. Gallo, S. Grimaldi, F. Borgia, and M. Todaro et al. Inhibition of class I histone deacetylase with an apicidin derivative prevents cardiac hypertrophy and failure Cardiovasc Res 80 2008 416 424
-
(2008)
Cardiovasc Res
, vol.80
, pp. 416-424
-
-
Gallo, P.1
Latronico, M.V.2
Gallo, P.3
Grimaldi, S.4
Borgia, F.5
Todaro, M.6
-
39
-
-
80055077899
-
HDAC4 protein regulates HIF1alpha protein lysine acetylation and cancer cell response to hypoxia
-
H. Geng, C.T. Harvey, J. Pittsenbarger, Q. Liu, T.M. Beer, and C. Xue et al. HDAC4 protein regulates HIF1alpha protein lysine acetylation and cancer cell response to hypoxia J Biol Chem 286 2011 38095 38102
-
(2011)
J Biol Chem
, vol.286
, pp. 38095-38102
-
-
Geng, H.1
Harvey, C.T.2
Pittsenbarger, J.3
Liu, Q.4
Beer, T.M.5
Xue, C.6
-
40
-
-
0036083396
-
The ubiquitin-proteasome proteolytic pathway: Destruction for the sake of construction
-
M.H. Glickman, and A. Ciechanover The ubiquitin-proteasome proteolytic pathway: destruction for the sake of construction Physiol Rev 82 2002 373 428
-
(2002)
Physiol Rev
, vol.82
, pp. 373-428
-
-
Glickman, M.H.1
Ciechanover, A.2
-
41
-
-
28044471827
-
Acetylation and deacetylation of non-histone proteins
-
M.A. Glozak, N. Sengupta, X. Zhang, and E. Seto Acetylation and deacetylation of non-histone proteins Gene 363 2005 15 23
-
(2005)
Gene
, vol.363
, pp. 15-23
-
-
Glozak, M.A.1
Sengupta, N.2
Zhang, X.3
Seto, E.4
-
42
-
-
67650520173
-
Protein kinase A-regulated assembly of a MEF2{middle dot}HDAC4 repressor complex controls c-Jun expression in vascular smooth muscle cells
-
J.W. Gordon, C. Pagiatakis, J. Salma, M. Du, J.J. Andreucci, and J. Zhao et al. Protein kinase A-regulated assembly of a MEF2{middle dot}HDAC4 repressor complex controls c-Jun expression in vascular smooth muscle cells J Biol Chem 284 2009 19027 19042
-
(2009)
J Biol Chem
, vol.284
, pp. 19027-19042
-
-
Gordon, J.W.1
Pagiatakis, C.2
Salma, J.3
Du, M.4
Andreucci, J.J.5
Zhao, J.6
-
43
-
-
54049090410
-
Histone deacetylase inhibition reduces myocardial ischemia-reperfusion injury in mice
-
A. Granger, I. Abdullah, F. Huebner, A. Stout, T. Wang, and T. Huebner et al. Histone deacetylase inhibition reduces myocardial ischemia-reperfusion injury in mice FASEB J 22 2008 3549 3560
-
(2008)
FASEB J
, vol.22
, pp. 3549-3560
-
-
Granger, A.1
Abdullah, I.2
Huebner, F.3
Stout, A.4
Wang, T.5
Huebner, T.6
-
44
-
-
0030797585
-
Activation of p53 sequence-specific DNA binding by acetylation of the p53 C-terminal domain
-
W. Gu, and R.G. Roeder Activation of p53 sequence-specific DNA binding by acetylation of the p53 C-terminal domain Cell 90 1997 595 606
-
(1997)
Cell
, vol.90
, pp. 595-606
-
-
Gu, W.1
Roeder, R.G.2
-
45
-
-
79953760389
-
H3 lysine 4 is acetylated at active gene promoters and is regulated by H3 lysine 4 methylation
-
B. Guillemette, P. Drogaris, H.H. Lin, H. Armstrong, K. Hiragami-Hamada, and A. Imhof et al. H3 lysine 4 is acetylated at active gene promoters and is regulated by H3 lysine 4 methylation PLoS Genet 7 2011 e1001354
-
(2011)
PLoS Genet
, vol.7
, pp. 1001354
-
-
Guillemette, B.1
Drogaris, P.2
Lin, H.H.3
Armstrong, H.4
Hiragami-Hamada, K.5
Imhof, A.6
-
46
-
-
72449139586
-
Abrogation of TGF-beta1-induced fibroblast-myofibroblast differentiation by histone deacetylase inhibition
-
W. Guo, B. Shan, R.C. Klingsberg, X. Qin, and J.A. Lasky Abrogation of TGF-beta1-induced fibroblast-myofibroblast differentiation by histone deacetylase inhibition Am J Physiol Lung Cell Mol Physiol 297 2009 L864 L870
-
(2009)
Am J Physiol Lung Cell Mol Physiol
, vol.297
-
-
Guo, W.1
Shan, B.2
Klingsberg, R.C.3
Qin, X.4
Lasky, J.A.5
-
47
-
-
53449086522
-
VEGF stimulates HDAC7 phosphorylation and cytoplasmic accumulation modulating matrix metalloproteinase expression and angiogenesis
-
C.H. Ha, B.S. Jhun, H.Y. Kao, and Z.G. Jin VEGF stimulates HDAC7 phosphorylation and cytoplasmic accumulation modulating matrix metalloproteinase expression and angiogenesis Arterioscler Thromb Vasc Biol 28 2008 1782 1788
-
(2008)
Arterioscler Thromb Vasc Biol
, vol.28
, pp. 1782-1788
-
-
Ha, C.H.1
Jhun, B.S.2
Kao, H.Y.3
Jin, Z.G.4
-
48
-
-
77957261983
-
PKA phosphorylates histone deacetylase 5 and prevents its nuclear export, leading to the inhibition of gene transcription and cardiomyocyte hypertrophy
-
C.H. Ha, J.Y. Kim, J. Zhao, W. Wang, B.S. Jhun, and C. Wong et al. PKA phosphorylates histone deacetylase 5 and prevents its nuclear export, leading to the inhibition of gene transcription and cardiomyocyte hypertrophy Proc Natl Acad Sci U S A 107 2010 15467 15472
-
(2010)
Proc Natl Acad Sci U S A
, vol.107
, pp. 15467-15472
-
-
Ha, C.H.1
Kim, J.Y.2
Zhao, J.3
Wang, W.4
Jhun, B.S.5
Wong, C.6
-
49
-
-
45749116898
-
Protein kinase D-dependent phosphorylation and nuclear export of histone deacetylase 5 mediates vascular endothelial growth factor-induced gene expression and angiogenesis
-
C.H. Ha, W. Wang, B.S. Jhun, C. Wong, A. Hausser, and K. Pfizenmaier et al. Protein kinase D-dependent phosphorylation and nuclear export of histone deacetylase 5 mediates vascular endothelial growth factor-induced gene expression and angiogenesis J Biol Chem 283 2008 14590 14599
-
(2008)
J Biol Chem
, vol.283
, pp. 14590-14599
-
-
Ha, C.H.1
Wang, W.2
Jhun, B.S.3
Wong, C.4
Hausser, A.5
Pfizenmaier, K.6
-
50
-
-
57749170458
-
The many roles of histone deacetylases in development and physiology: Implications for disease and therapy
-
M. Haberland, R.L. Montgomery, and E.N. Olson The many roles of histone deacetylases in development and physiology: implications for disease and therapy Nat Rev Genet 10 2009 32 42
-
(2009)
Nat Rev Genet
, vol.10
, pp. 32-42
-
-
Haberland, M.1
Montgomery, R.L.2
Olson, E.N.3
-
51
-
-
77954013043
-
Differential effects of selective HDAC inhibitors on macrophage inflammatory responses to the Toll-like receptor 4 agonist LPS
-
M.A. Halili, M.R. Andrews, L.I. Labzin, K. Schroder, G. Matthias, and C. Cao et al. Differential effects of selective HDAC inhibitors on macrophage inflammatory responses to the Toll-like receptor 4 agonist LPS J Leukoc Biol 87 2010 1103 1114
-
(2010)
J Leukoc Biol
, vol.87
, pp. 1103-1114
-
-
Halili, M.A.1
Andrews, M.R.2
Labzin, L.I.3
Schroder, K.4
Matthias, G.5
Cao, C.6
-
52
-
-
84883788666
-
Epigenetic targeting of histone deacetylase: Therapeutic potential in Parkinson's disease?
-
I.F. Harrison, and D.T. Dexter Epigenetic targeting of histone deacetylase: therapeutic potential in Parkinson's disease? Pharmacol Ther 140 2013 34 52
-
(2013)
Pharmacol Ther
, vol.140
, pp. 34-52
-
-
Harrison, I.F.1
Dexter, D.T.2
-
53
-
-
84862279509
-
Neurohormonal regulation of cardiac histone deacetylase 5 nuclear localization by phosphorylation-dependent and phosphorylation-independent mechanisms
-
R.S. Haworth, K. Stathopoulou, A.J. Candasamy, and M. Avkiran Neurohormonal regulation of cardiac histone deacetylase 5 nuclear localization by phosphorylation-dependent and phosphorylation-independent mechanisms Circ Res 110 2012 1585 1595
-
(2012)
Circ Res
, vol.110
, pp. 1585-1595
-
-
Haworth, R.S.1
Stathopoulou, K.2
Candasamy, A.J.3
Avkiran, M.4
-
54
-
-
41449086790
-
Cardiac plasticity
-
J.A. Hill, and E.N. Olson Cardiac plasticity N Engl J Med 358 2008 1370 1380
-
(2008)
N Engl J Med
, vol.358
, pp. 1370-1380
-
-
Hill, J.A.1
Olson, E.N.2
-
55
-
-
0033786922
-
Protein tyrosine kinase structure and function
-
S.R. Hubbard, and J.H. Till Protein tyrosine kinase structure and function Annu Rev Biochem 69 2000 373 398
-
(2000)
Annu Rev Biochem
, vol.69
, pp. 373-398
-
-
Hubbard, S.R.1
Till, J.H.2
-
56
-
-
0037161744
-
HDAC6 is a microtubule-associated deacetylase
-
C. Hubbert, A. Guardiola, R. Shao, Y. Kawaguchi, A. Ito, and A. Nixon et al. HDAC6 is a microtubule-associated deacetylase Nature 417 2002 455 458
-
(2002)
Nature
, vol.417
, pp. 455-458
-
-
Hubbert, C.1
Guardiola, A.2
Shao, R.3
Kawaguchi, Y.4
Ito, A.5
Nixon, A.6
-
57
-
-
84884931588
-
Noncommunicable diseases
-
D.J. Hunter, and K.S. Reddy Noncommunicable diseases N Engl J Med 369 2013 1336 1343
-
(2013)
N Engl J Med
, vol.369
, pp. 1336-1343
-
-
Hunter, D.J.1
Reddy, K.S.2
-
58
-
-
0027258140
-
Hypercholesterolemia in low density lipoprotein receptor knockout mice and its reversal by adenovirus-mediated gene delivery
-
S. Ishibashi, M.S. Brown, J.L. Goldstein, R.D. Gerard, R.E. Hammer, and J. Herz Hypercholesterolemia in low density lipoprotein receptor knockout mice and its reversal by adenovirus-mediated gene delivery J Clin Invest 92 1993 883 893
-
(1993)
J Clin Invest
, vol.92
, pp. 883-893
-
-
Ishibashi, S.1
Brown, M.S.2
Goldstein, J.L.3
Gerard, R.D.4
Hammer, R.E.5
Herz, J.6
-
59
-
-
18044375365
-
Homeobox protein Hop functions in the adult cardiac conduction system
-
F.A. Ismat, M. Zhang, H. Kook, B. Huang, R. Zhou, and V.A. Ferrari et al. Homeobox protein Hop functions in the adult cardiac conduction system Circ Res 96 2005 898 903
-
(2005)
Circ Res
, vol.96
, pp. 898-903
-
-
Ismat, F.A.1
Zhang, M.2
Kook, H.3
Huang, B.4
Zhou, R.5
Ferrari, V.A.6
-
60
-
-
0037112901
-
MDM2-HDAC1-mediated deacetylation of p53 is required for its degradation
-
A. Ito, Y. Kawaguchi, C.H. Lai, J.J. Kovacs, Y. Higashimoto, and E. Appella et al. MDM2-HDAC1-mediated deacetylation of p53 is required for its degradation EMBO J 21 2002 6236 6245
-
(2002)
EMBO J
, vol.21
, pp. 6236-6245
-
-
Ito, A.1
Kawaguchi, Y.2
Lai, C.H.3
Kovacs, J.J.4
Higashimoto, Y.5
Appella, E.6
-
61
-
-
31344446119
-
Histone deacetylase 2-mediated deacetylation of the glucocorticoid receptor enables NF-kappaB suppression
-
K. Ito, S. Yamamura, S. Essilfie-Quaye, B. Cosio, M. Ito, and P.J. Barnes et al. Histone deacetylase 2-mediated deacetylation of the glucocorticoid receptor enables NF-kappaB suppression J Exp Med 203 2006 7 13
-
(2006)
J Exp Med
, vol.203
, pp. 7-13
-
-
Ito, K.1
Yamamura, S.2
Essilfie-Quaye, S.3
Cosio, B.4
Ito, M.5
Barnes, P.J.6
-
62
-
-
33751059239
-
A series of novel, potent, and selective histone deacetylase inhibitors
-
P. Jones, S. Altamura, P.K. Chakravarty, O. Cecchetti, R. De Francesco, and P. Gallinari et al. A series of novel, potent, and selective histone deacetylase inhibitors Bioorg Med Chem Lett 16 2006 5948 5952
-
(2006)
Bioorg Med Chem Lett
, vol.16
, pp. 5948-5952
-
-
Jones, P.1
Altamura, S.2
Chakravarty, P.K.3
Cecchetti, O.4
De Francesco, R.5
Gallinari, P.6
-
63
-
-
40849086606
-
Probing the elusive catalytic activity of vertebrate class IIa histone deacetylases
-
P. Jones, S. Altamura, R. De Francesco, P. Gallinari, A. Lahm, and P. Neddermann et al. Probing the elusive catalytic activity of vertebrate class IIa histone deacetylases Bioorg Med Chem Lett 18 2008 1814 1819
-
(2008)
Bioorg Med Chem Lett
, vol.18
, pp. 1814-1819
-
-
Jones, P.1
Altamura, S.2
De Francesco, R.3
Gallinari, P.4
Lahm, A.5
Neddermann, P.6
-
64
-
-
84874380158
-
Histone deacetylase 9 promotes angiogenesis by targeting the antiangiogenic microRNA-17-92 cluster in endothelial cells
-
D. Kaluza, J. Kroll, S. Gesierich, Y. Manavski, J.N. Boeckel, and C. Doebele et al. Histone deacetylase 9 promotes angiogenesis by targeting the antiangiogenic microRNA-17-92 cluster in endothelial cells Arterioscler Thromb Vasc Biol 33 2013 533 543
-
(2013)
Arterioscler Thromb Vasc Biol
, vol.33
, pp. 533-543
-
-
Kaluza, D.1
Kroll, J.2
Gesierich, S.3
Manavski, Y.4
Boeckel, J.N.5
Doebele, C.6
-
65
-
-
80054881600
-
Class IIb HDAC6 regulates endothelial cell migration and angiogenesis by deacetylation of cortactin
-
D. Kaluza, J. Kroll, S. Gesierich, T.P. Yao, R.A. Boon, and E. Hergenreider et al. Class IIb HDAC6 regulates endothelial cell migration and angiogenesis by deacetylation of cortactin EMBO J 30 2011 4142 4156
-
(2011)
EMBO J
, vol.30
, pp. 4142-4156
-
-
Kaluza, D.1
Kroll, J.2
Gesierich, S.3
Yao, T.P.4
Boon, R.A.5
Hergenreider, E.6
-
66
-
-
0037016696
-
Isolation and characterization of mammalian HDAC10, a novel histone deacetylase
-
H.Y. Kao, C.H. Lee, A. Komarov, C.C. Han, and R.M. Evans Isolation and characterization of mammalian HDAC10, a novel histone deacetylase J Biol Chem 277 2002 187 193
-
(2002)
J Biol Chem
, vol.277
, pp. 187-193
-
-
Kao, H.Y.1
Lee, C.H.2
Komarov, A.3
Han, C.C.4
Evans, R.M.5
-
67
-
-
21244431578
-
Acetylation of GATA-4 is involved in the differentiation of embryonic stem cells into cardiac myocytes
-
T. Kawamura, K. Ono, T. Morimoto, H. Wada, M. Hirai, and K. Hidaka et al. Acetylation of GATA-4 is involved in the differentiation of embryonic stem cells into cardiac myocytes J Biol Chem 280 2005 19682 19688
-
(2005)
J Biol Chem
, vol.280
, pp. 19682-19688
-
-
Kawamura, T.1
Ono, K.2
Morimoto, T.3
Wada, H.4
Hirai, M.5
Hidaka, K.6
-
68
-
-
58149352444
-
Activation of histone deacetylase 2 by inducible heat shock protein 70 in cardiac hypertrophy
-
H.J. Kee, G.H. Eom, H. Joung, S. Shin, J.R. Kim, and Y.K. Cho et al. Activation of histone deacetylase 2 by inducible heat shock protein 70 in cardiac hypertrophy Circ Res 103 2008 1259 1269
-
(2008)
Circ Res
, vol.103
, pp. 1259-1269
-
-
Kee, H.J.1
Eom, G.H.2
Joung, H.3
Shin, S.4
Kim, J.R.5
Cho, Y.K.6
-
69
-
-
70449095895
-
Kruppel-like factor 4 mediates histone deacetylase inhibitor-induced prevention of cardiac hypertrophy
-
H.J. Kee, and H. Kook Kruppel-like factor 4 mediates histone deacetylase inhibitor-induced prevention of cardiac hypertrophy J Mol Cell Cardiol 47 2009 770 780
-
(2009)
J Mol Cell Cardiol
, vol.47
, pp. 770-780
-
-
Kee, H.J.1
Kook, H.2
-
70
-
-
84863556840
-
Trichostatin A prevents neointimal hyperplasia via activation of Kruppel like factor 4
-
H.J. Kee, J.S. Kwon, S. Shin, Y. Ahn, M.H. Jeong, and H. Kook Trichostatin A prevents neointimal hyperplasia via activation of Kruppel like factor 4 Vascul Pharmacol 55 2011 127 134
-
(2011)
Vascul Pharmacol
, vol.55
, pp. 127-134
-
-
Kee, H.J.1
Kwon, J.S.2
Shin, S.3
Ahn, Y.4
Jeong, M.H.5
Kook, H.6
-
71
-
-
33644861578
-
Inhibition of histone deacetylation blocks cardiac hypertrophy induced by angiotensin II infusion and aortic banding
-
H.J. Kee, I.S. Sohn, K.I. Nam, J.E. Park, Y.R. Qian, and Z. Yin et al. Inhibition of histone deacetylation blocks cardiac hypertrophy induced by angiotensin II infusion and aortic banding Circulation 113 2006 51 59
-
(2006)
Circulation
, vol.113
, pp. 51-59
-
-
Kee, H.J.1
Sohn, I.S.2
Nam, K.I.3
Park, J.E.4
Qian, Y.R.5
Yin, Z.6
-
72
-
-
0035048449
-
Histone deacetylases induce angiogenesis by negative regulation of tumor suppressor genes
-
M.S. Kim, H.J. Kwon, Y.M. Lee, J.H. Baek, J.E. Jang, and S.W. Lee et al. Histone deacetylases induce angiogenesis by negative regulation of tumor suppressor genes Nat Med 7 2001 437 443
-
(2001)
Nat Med
, vol.7
, pp. 437-443
-
-
Kim, M.S.1
Kwon, H.J.2
Lee, Y.M.3
Baek, J.H.4
Jang, J.E.5
Lee, S.W.6
-
73
-
-
32944465688
-
Histone deacetylase inhibitor-mediated radiosensitization of human cancer cells: Class differences and the potential influence of p53
-
I.A. Kim, J.H. Shin, I.H. Kim, J.H. Kim, J.S. Kim, and H.G. Wu et al. Histone deacetylase inhibitor-mediated radiosensitization of human cancer cells: class differences and the potential influence of p53 Clin Cancer Res 12 2006 940 949
-
(2006)
Clin Cancer Res
, vol.12
, pp. 940-949
-
-
Kim, I.A.1
Shin, J.H.2
Kim, I.H.3
Kim, J.H.4
Kim, J.S.5
Wu, H.G.6
-
74
-
-
18444370302
-
The SUMO E3 ligase RanBP2 promotes modification of the HDAC4 deacetylase
-
O. Kirsh, J.S. Seeler, A. Pichler, A. Gast, S. Muller, and E. Miska et al. The SUMO E3 ligase RanBP2 promotes modification of the HDAC4 deacetylase EMBO J 21 2002 2682 2691
-
(2002)
EMBO J
, vol.21
, pp. 2682-2691
-
-
Kirsh, O.1
Seeler, J.S.2
Pichler, A.3
Gast, A.4
Muller, S.5
Miska, E.6
-
75
-
-
34250307630
-
The landscape of histone modifications across 1% of the human genome in five human cell lines
-
C.M. Koch, R.M. Andrews, P. Flicek, S.C. Dillon, U. Karaoz, and G.K. Clelland et al. The landscape of histone modifications across 1% of the human genome in five human cell lines Genome Res 17 2007 691 707
-
(2007)
Genome Res
, vol.17
, pp. 691-707
-
-
Koch, C.M.1
Andrews, R.M.2
Flicek, P.3
Dillon, S.C.4
Karaoz, U.5
Clelland, G.K.6
-
76
-
-
0035812709
-
Phosphorylation-dependent ubiquitination of cyclin e by the SCFFbw7 ubiquitin ligase
-
D.M. Koepp, L.K. Schaefer, X. Ye, K. Keyomarsi, C. Chu, and J.W. Harper et al. Phosphorylation-dependent ubiquitination of cyclin E by the SCFFbw7 ubiquitin ligase Science 294 2001 173 177
-
(2001)
Science
, vol.294
, pp. 173-177
-
-
Koepp, D.M.1
Schaefer, L.K.2
Ye, X.3
Keyomarsi, K.4
Chu, C.5
Harper, J.W.6
-
77
-
-
59149095347
-
HDAC2 deacetylates class II transactivator and suppresses its activity in macrophages and smooth muscle cells
-
X. Kong, M. Fang, P. Li, F. Fang, and Y. Xu HDAC2 deacetylates class II transactivator and suppresses its activity in macrophages and smooth muscle cells J Mol Cell Cardiol 46 2009 292 299
-
(2009)
J Mol Cell Cardiol
, vol.46
, pp. 292-299
-
-
Kong, X.1
Fang, M.2
Li, P.3
Fang, F.4
Xu, Y.5
-
78
-
-
33745173485
-
Suppression of class i and II histone deacetylases blunts pressure-overload cardiac hypertrophy
-
Y. Kong, P. Tannous, G. Lu, K. Berenji, B.A. Rothermel, and E.N. Olson et al. Suppression of class I and II histone deacetylases blunts pressure-overload cardiac hypertrophy Circulation 113 2006 2579 2588
-
(2006)
Circulation
, vol.113
, pp. 2579-2588
-
-
Kong, Y.1
Tannous, P.2
Lu, G.3
Berenji, K.4
Rothermel, B.A.5
Olson, E.N.6
-
79
-
-
85047694248
-
Cardiac hypertrophy and histone deacetylase-dependent transcriptional repression mediated by the atypical homeodomain protein Hop
-
H. Kook, J.J. Lepore, A.D. Gitler, M.M. Lu, W. Wing-Man Yung, and J. Mackay et al. Cardiac hypertrophy and histone deacetylase-dependent transcriptional repression mediated by the atypical homeodomain protein Hop J Clin Invest 112 2003 863 871
-
(2003)
J Clin Invest
, vol.112
, pp. 863-871
-
-
Kook, H.1
Lepore, J.J.2
Gitler, A.D.3
Lu, M.M.4
Wing-Man Yung, W.5
Mackay, J.6
-
80
-
-
84876410004
-
Histone deacetylase inhibition attenuates transcriptional activity of mineralocorticoid receptor through its acetylation and prevents development of hypertension
-
H.A. Lee, D.Y. Lee, H.M. Cho, S.Y. Kim, Y. Iwasaki, and I.K. Kim Histone deacetylase inhibition attenuates transcriptional activity of mineralocorticoid receptor through its acetylation and prevents development of hypertension Circ Res 112 2013 1004 1012
-
(2013)
Circ Res
, vol.112
, pp. 1004-1012
-
-
Lee, H.A.1
Lee, D.Y.2
Cho, H.M.3
Kim, S.Y.4
Iwasaki, Y.5
Kim, I.K.6
-
81
-
-
34547886153
-
Inhibition of histone deacetylase on ventricular remodeling in infarcted rats
-
T.M. Lee, M.S. Lin, and N.C. Chang Inhibition of histone deacetylase on ventricular remodeling in infarcted rats Am J Physiol Heart Circ Physiol 293 2007 H968 H977
-
(2007)
Am J Physiol Heart Circ Physiol
, vol.293
-
-
Lee, T.M.1
Lin, M.S.2
Chang, N.C.3
-
82
-
-
11144353713
-
Acetylation of beta-catenin by p300 regulates beta-catenin-Tcf4 interaction
-
L. Levy, Y. Wei, C. Labalette, Y. Wu, C.A. Renard, and M.A. Buendia et al. Acetylation of beta-catenin by p300 regulates beta-catenin-Tcf4 interaction Mol Cell Biol 24 2004 3404 3414
-
(2004)
Mol Cell Biol
, vol.24
, pp. 3404-3414
-
-
Levy, L.1
Wei, Y.2
Labalette, C.3
Wu, Y.4
Renard, C.A.5
Buendia, M.A.6
-
83
-
-
0037184969
-
Acetylation of p53 inhibits its ubiquitination by Mdm2
-
M. Li, J. Luo, C.L. Brooks, and W. Gu Acetylation of p53 inhibits its ubiquitination by Mdm2 J Biol Chem 277 2002 50607 50611
-
(2002)
J Biol Chem
, vol.277
, pp. 50607-50611
-
-
Li, M.1
Luo, J.2
Brooks, C.L.3
Gu, W.4
-
84
-
-
79953219078
-
Microtubule-associated deacetylase HDAC6 promotes angiogenesis by regulating cell migration in an EB1-dependent manner
-
D. Li, S. Xie, Y. Ren, L. Huo, J. Gao, and D. Cui et al. Microtubule-associated deacetylase HDAC6 promotes angiogenesis by regulating cell migration in an EB1-dependent manner Protein Cell 2 2011 150 160
-
(2011)
Protein Cell
, vol.2
, pp. 150-160
-
-
Li, D.1
Xie, S.2
Ren, Y.3
Huo, L.4
Gao, J.5
Cui, D.6
-
85
-
-
0036683093
-
Phosphorylation-dependent ubiquitylation and degradation of androgen receptor by Akt require Mdm2 E3 ligase
-
H.K. Lin, L. Wang, Y.C. Hu, S. Altuwaijri, and C. Chang Phosphorylation-dependent ubiquitylation and degradation of androgen receptor by Akt require Mdm2 E3 ligase EMBO J 21 2002 4037 4048
-
(2002)
EMBO J
, vol.21
, pp. 4037-4048
-
-
Lin, H.K.1
Wang, L.2
Hu, Y.C.3
Altuwaijri, S.4
Chang, C.5
-
86
-
-
55649123444
-
Histone-deacetylase inhibition reverses atrial arrhythmia inducibility and fibrosis in cardiac hypertrophy independent of angiotensin
-
F. Liu, M.D. Levin, N.B. Petrenko, M.M. Lu, T. Wang, and L.J. Yuan et al. Histone-deacetylase inhibition reverses atrial arrhythmia inducibility and fibrosis in cardiac hypertrophy independent of angiotensin J Mol Cell Cardiol 45 2008 715 723
-
(2008)
J Mol Cell Cardiol
, vol.45
, pp. 715-723
-
-
Liu, F.1
Levin, M.D.2
Petrenko, N.B.3
Lu, M.M.4
Wang, T.5
Yuan, L.J.6
-
87
-
-
80555124930
-
Denitrosylation of HDAC2 by targeting Nrf2 restores glucocorticosteroid sensitivity in macrophages from COPD patients
-
D. Malhotra, R.K. Thimmulappa, N. Mercado, K. Ito, P. Kombairaju, and S. Kumar et al. Denitrosylation of HDAC2 by targeting Nrf2 restores glucocorticosteroid sensitivity in macrophages from COPD patients J Clin Invest 121 2011 4289 4302
-
(2011)
J Clin Invest
, vol.121
, pp. 4289-4302
-
-
Malhotra, D.1
Thimmulappa, R.K.2
Mercado, N.3
Ito, K.4
Kombairaju, P.5
Kumar, S.6
-
88
-
-
77951276571
-
Histone deacetylase 7 controls endothelial cell growth through modulation of beta-catenin
-
A. Margariti, A. Zampetaki, Q. Xiao, B. Zhou, E. Karamariti, and D. Martin et al. Histone deacetylase 7 controls endothelial cell growth through modulation of beta-catenin Circ Res 106 2010 1202 1211
-
(2010)
Circ Res
, vol.106
, pp. 1202-1211
-
-
Margariti, A.1
Zampetaki, A.2
Xiao, Q.3
Zhou, B.4
Karamariti, E.5
Martin, D.6
-
90
-
-
42449144793
-
Protein phosphatase 2A controls the activity of histone deacetylase 7 during T cell apoptosis and angiogenesis
-
M. Martin, M. Potente, V. Janssens, D. Vertommen, J.C. Twizere, and M.H. Rider et al. Protein phosphatase 2A controls the activity of histone deacetylase 7 during T cell apoptosis and angiogenesis Proc Natl Acad Sci U S A 105 2008 4727 4732
-
(2008)
Proc Natl Acad Sci U S A
, vol.105
, pp. 4727-4732
-
-
Martin, M.1
Potente, M.2
Janssens, V.3
Vertommen, D.4
Twizere, J.C.5
Rider, M.H.6
-
92
-
-
74049116297
-
Histone deacetylase modulates the proinflammatory and -fibrotic changes in tubulointerstitial injury
-
T. Marumo, K. Hishikawa, M. Yoshikawa, J. Hirahashi, S. Kawachi, and T. Fujita Histone deacetylase modulates the proinflammatory and -fibrotic changes in tubulointerstitial injury Am J Physiol Renal Physiol 298 2010 F133 F141
-
(2010)
Am J Physiol Renal Physiol
, vol.298
-
-
Marumo, T.1
Hishikawa, K.2
Yoshikawa, M.3
Hirahashi, J.4
Kawachi, S.5
Fujita, T.6
-
93
-
-
0034737483
-
The beta(2)-adrenergic receptor mediates extracellular signal-regulated kinase activation via assembly of a multi-receptor complex with the epidermal growth factor receptor
-
S. Maudsley, K.L. Pierce, A.M. Zamah, W.E. Miller, S. Ahn, and Y. Daaka et al. The beta(2)-adrenergic receptor mediates extracellular signal-regulated kinase activation via assembly of a multi-receptor complex with the epidermal growth factor receptor J Biol Chem 275 2000 9572 9580
-
(2000)
J Biol Chem
, vol.275
, pp. 9572-9580
-
-
Maudsley, S.1
Pierce, K.L.2
Zamah, A.M.3
Miller, W.E.4
Ahn, S.5
Daaka, Y.6
-
94
-
-
41149113442
-
Preventing heart disease in the 21st century: Implications of the Pathobiological Determinants of Atherosclerosis in Youth (PDAY) study
-
H.C. McGill Jr., C.A. McMahan, and S.S. Gidding Preventing heart disease in the 21st century: implications of the Pathobiological Determinants of Atherosclerosis in Youth (PDAY) study Circulation 117 2008 1216 1227
-
(2008)
Circulation
, vol.117
, pp. 1216-1227
-
-
McGill, Jr.H.C.1
McMahan, C.A.2
Gidding, S.S.3
-
95
-
-
0034597816
-
Signal-dependent nuclear export of a histone deacetylase regulates muscle differentiation
-
T.A. McKinsey, C.L. Zhang, J. Lu, and E.N. Olson Signal-dependent nuclear export of a histone deacetylase regulates muscle differentiation Nature 408 2000 106 111
-
(2000)
Nature
, vol.408
, pp. 106-111
-
-
McKinsey, T.A.1
Zhang, C.L.2
Lu, J.3
Olson, E.N.4
-
96
-
-
0034687741
-
Activation of the myocyte enhancer factor-2 transcription factor by calcium/calmodulin-dependent protein kinase-stimulated binding of 14-3-3 to histone deacetylase 5
-
T.A. McKinsey, C.L. Zhang, and E.N. Olson Activation of the myocyte enhancer factor-2 transcription factor by calcium/calmodulin-dependent protein kinase-stimulated binding of 14-3-3 to histone deacetylase 5 Proc Natl Acad Sci U S A 97 2000 14400 14405
-
(2000)
Proc Natl Acad Sci U S A
, vol.97
, pp. 14400-14405
-
-
McKinsey, T.A.1
Zhang, C.L.2
Olson, E.N.3
-
97
-
-
0034523266
-
SUMO - Nonclassical ubiquitin
-
F. Melchior SUMO - nonclassical ubiquitin Annu Rev Cell Dev Biol 16 2000 591 626
-
(2000)
Annu Rev Cell Dev Biol
, vol.16
, pp. 591-626
-
-
Melchior, F.1
-
98
-
-
67651036161
-
All-trans retinoic acid increases KLF4 acetylation by inducing HDAC2 phosphorylation and its dissociation from KLF4 in vascular smooth muscle cells
-
F. Meng, M. Han, B. Zheng, C. Wang, R. Zhang, and X.H. Zhang et al. All-trans retinoic acid increases KLF4 acetylation by inducing HDAC2 phosphorylation and its dissociation from KLF4 in vascular smooth muscle cells Biochem Biophys Res Commun 387 2009 13 18
-
(2009)
Biochem Biophys Res Commun
, vol.387
, pp. 13-18
-
-
Meng, F.1
Han, M.2
Zheng, B.3
Wang, C.4
Zhang, R.5
Zhang, X.H.6
-
99
-
-
30344477367
-
Histone deacetylase inhibitors and the promise of epigenetic (and more) treatments for cancer
-
S. Minucci, and P.G. Pelicci Histone deacetylase inhibitors and the promise of epigenetic (and more) treatments for cancer Nat Rev Cancer 6 2006 38 51
-
(2006)
Nat Rev Cancer
, vol.6
, pp. 38-51
-
-
Minucci, S.1
Pelicci, P.G.2
-
100
-
-
34347401218
-
Regulation of receptors and transporters by ubiquitination: New insights into surprisingly similar mechanisms
-
M. Miranda, and A. Sorkin Regulation of receptors and transporters by ubiquitination: new insights into surprisingly similar mechanisms Mol Interv 7 2007 157 167
-
(2007)
Mol Interv
, vol.7
, pp. 157-167
-
-
Miranda, M.1
Sorkin, A.2
-
101
-
-
0032540267
-
A calcineurin-dependent transcriptional pathway for cardiac hypertrophy
-
J.D. Molkentin, J.R. Lu, C.L. Antos, B. Markham, J. Richardson, and J. Robbins et al. A calcineurin-dependent transcriptional pathway for cardiac hypertrophy Cell 93 1998 215 228
-
(1998)
Cell
, vol.93
, pp. 215-228
-
-
Molkentin, J.D.1
Lu, J.R.2
Antos, C.L.3
Markham, B.4
Richardson, J.5
Robbins, J.6
-
102
-
-
84857501462
-
Genetics and arrhythmias: Diagnostic and prognostic applications
-
N. Monteforte, C. Napolitano, and S.G. Priori Genetics and arrhythmias: diagnostic and prognostic applications Rev Esp Cardiol 65 2012 278 286
-
(2012)
Rev Esp Cardiol
, vol.65
, pp. 278-286
-
-
Monteforte, N.1
Napolitano, C.2
Priori, S.G.3
-
103
-
-
34447511648
-
Histone deacetylases 1 and 2 redundantly regulate cardiac morphogenesis, growth, and contractility
-
R.L. Montgomery, C.A. Davis, M.J. Potthoff, M. Haberland, J. Fielitz, and X. Qi et al. Histone deacetylases 1 and 2 redundantly regulate cardiac morphogenesis, growth, and contractility Genes Dev 21 2007 1790 1802
-
(2007)
Genes Dev
, vol.21
, pp. 1790-1802
-
-
Montgomery, R.L.1
Davis, C.A.2
Potthoff, M.J.3
Haberland, M.4
Fielitz, J.5
Qi, X.6
-
104
-
-
37349089053
-
Histone deacetylase 7 silencing alters endothelial cell migration, a key step in angiogenesis
-
D. Mottet, A. Bellahcene, S. Pirotte, D. Waltregny, C. Deroanne, and V. Lamour et al. Histone deacetylase 7 silencing alters endothelial cell migration, a key step in angiogenesis Circ Res 101 2007 1237 1246
-
(2007)
Circ Res
, vol.101
, pp. 1237-1246
-
-
Mottet, D.1
Bellahcene, A.2
Pirotte, S.3
Waltregny, D.4
Deroanne, C.5
Lamour, V.6
-
105
-
-
82955247088
-
Histone deacetylase 3 is an epigenomic brake in macrophage alternative activation
-
S.E. Mullican, C.A. Gaddis, T. Alenghat, M.G. Nair, P.R. Giacomin, and L.J. Everett et al. Histone deacetylase 3 is an epigenomic brake in macrophage alternative activation Genes Dev 25 2011 2480 2488
-
(2011)
Genes Dev
, vol.25
, pp. 2480-2488
-
-
Mullican, S.E.1
Gaddis, C.A.2
Alenghat, T.3
Nair, M.G.4
Giacomin, P.R.5
Everett, L.J.6
-
106
-
-
11144356049
-
Haematopoietic stem cells do not transdifferentiate into cardiac myocytes in myocardial infarcts
-
C.E. Murry, M.H. Soonpaa, H. Reinecke, H. Nakajima, H.O. Nakajima, and M. Rubart et al. Haematopoietic stem cells do not transdifferentiate into cardiac myocytes in myocardial infarcts Nature 428 2004 664 668
-
(2004)
Nature
, vol.428
, pp. 664-668
-
-
Murry, C.E.1
Soonpaa, M.H.2
Reinecke, H.3
Nakajima, H.4
Nakajima, H.O.5
Rubart, M.6
-
107
-
-
67650083046
-
Selective class II HDAC inhibitors impair myogenesis by modulating the stability and activity of HDAC-MEF2 complexes
-
A. Nebbioso, F. Manzo, M. Miceli, M. Conte, L. Manente, and A. Baldi et al. Selective class II HDAC inhibitors impair myogenesis by modulating the stability and activity of HDAC-MEF2 complexes EMBO Rep 10 2009 776 782
-
(2009)
EMBO Rep
, vol.10
, pp. 776-782
-
-
Nebbioso, A.1
Manzo, F.2
Miceli, M.3
Conte, M.4
Manente, L.5
Baldi, A.6
-
108
-
-
0033055983
-
A histone deacetylase inhibitor, trichostatin A, suppresses myofibroblastic differentiation of rat hepatic stellate cells in primary culture
-
T. Niki, K. Rombouts, P. De Bleser, K. De Smet, V. Rogiers, and D. Schuppan et al. A histone deacetylase inhibitor, trichostatin A, suppresses myofibroblastic differentiation of rat hepatic stellate cells in primary culture Hepatology 29 1999 858 867
-
(1999)
Hepatology
, vol.29
, pp. 858-867
-
-
Niki, T.1
Rombouts, K.2
De Bleser, P.3
De Smet, K.4
Rogiers, V.5
Schuppan, D.6
-
109
-
-
69449107940
-
Histone deacetylase-2 is a key regulator of diabetes- and transforming growth factor-beta1-induced renal injury
-
H. Noh, E.Y. Oh, J.Y. Seo, M.R. Yu, Y.O. Kim, and H. Ha et al. Histone deacetylase-2 is a key regulator of diabetes- and transforming growth factor-beta1-induced renal injury Am J Physiol Renal Physiol 297 2009 F729 F739
-
(2009)
Am J Physiol Renal Physiol
, vol.297
-
-
Noh, H.1
Oh, E.Y.2
Seo, J.Y.3
Yu, M.R.4
Kim, Y.O.5
Ha, H.6
-
110
-
-
52149108919
-
S-Nitrosylation of histone deacetylase 2 induces chromatin remodelling in neurons
-
A. Nott, P.M. Watson, J.D. Robinson, L. Crepaldi, and A. Riccio S-Nitrosylation of histone deacetylase 2 induces chromatin remodelling in neurons Nature 455 2008 411 415
-
(2008)
Nature
, vol.455
, pp. 411-415
-
-
Nott, A.1
Watson, P.M.2
Robinson, J.D.3
Crepaldi, L.4
Riccio, A.5
-
111
-
-
33847227712
-
Trichostatin A, an inhibitor of histone deacetylase, inhibits smooth muscle cell proliferation via induction of p21(WAF1)
-
H. Okamoto, Y. Fujioka, A. Takahashi, T. Takahashi, T. Taniguchi, and Y. Ishikawa et al. Trichostatin A, an inhibitor of histone deacetylase, inhibits smooth muscle cell proliferation via induction of p21(WAF1) J Atheroscler Thromb 13 2006 183 191
-
(2006)
J Atheroscler Thromb
, vol.13
, pp. 183-191
-
-
Okamoto, H.1
Fujioka, Y.2
Takahashi, A.3
Takahashi, T.4
Taniguchi, T.5
Ishikawa, Y.6
-
112
-
-
0344237360
-
DNA-PK is activated by nucleosomes and phosphorylates H2AX within the nucleosomes in an acetylation-dependent manner
-
E.J. Park, D.W. Chan, J.H. Park, M.A. Oettinger, and J. Kwon DNA-PK is activated by nucleosomes and phosphorylates H2AX within the nucleosomes in an acetylation-dependent manner Nucleic Acids Res 31 2003 6819 6827
-
(2003)
Nucleic Acids Res
, vol.31
, pp. 6819-6827
-
-
Park, E.J.1
Chan, D.W.2
Park, J.H.3
Oettinger, M.A.4
Kwon, J.5
-
113
-
-
0035861594
-
Histone deacetylase 1 phosphorylation promotes enzymatic activity and complex formation
-
M.K. Pflum, J.K. Tong, W.S. Lane, and S.L. Schreiber Histone deacetylase 1 phosphorylation promotes enzymatic activity and complex formation J Biol Chem 276 2001 47733 47741
-
(2001)
J Biol Chem
, vol.276
, pp. 47733-47741
-
-
Pflum, M.K.1
Tong, J.K.2
Lane, W.S.3
Schreiber, S.L.4
-
114
-
-
84878651723
-
Roles of histone deacetylation and AMP kinase in regulation of cardiomyocyte PGC-1alpha gene expression in hypoxia
-
A. Ramjiawan, R.A. Bagchi, A. Blant, L. Albak, M.A. Cavasin, and T.R. Horn et al. Roles of histone deacetylation and AMP kinase in regulation of cardiomyocyte PGC-1alpha gene expression in hypoxia Am J Physiol Cell Physiol 304 2013 C1064 C1072
-
(2013)
Am J Physiol Cell Physiol
, vol.304
-
-
Ramjiawan, A.1
Bagchi, R.A.2
Blant, A.3
Albak, L.4
Cavasin, M.A.5
Horn, T.R.6
-
115
-
-
84863720716
-
Epistatic rescue of Nkx2.5 adult cardiac conduction disease phenotypes by prospero-related homeobox protein 1 and HDAC3
-
C.A. Risebro, L.K. Petchey, N. Smart, J. Gomes, J. Clark, and J.M. Vieira et al. Epistatic rescue of Nkx2.5 adult cardiac conduction disease phenotypes by prospero-related homeobox protein 1 and HDAC3 Circ Res 111 2012 e19 e31
-
(2012)
Circ Res
, vol.111
-
-
Risebro, C.A.1
Petchey, L.K.2
Smart, N.3
Gomes, J.4
Clark, J.5
Vieira, J.M.6
-
116
-
-
0033552883
-
Atherosclerosis - An inflammatory disease
-
R. Ross Atherosclerosis - an inflammatory disease N Engl J Med 340 1999 115 126
-
(1999)
N Engl J Med
, vol.340
, pp. 115-126
-
-
Ross, R.1
-
117
-
-
0036842460
-
Inhibitors of histone deacetylation downregulate the expression of endothelial nitric oxide synthase and compromise endothelial cell function in vasorelaxation and angiogenesis
-
L. Rossig, H. Li, B. Fisslthaler, C. Urbich, I. Fleming, and U. Forstermann et al. Inhibitors of histone deacetylation downregulate the expression of endothelial nitric oxide synthase and compromise endothelial cell function in vasorelaxation and angiogenesis Circ Res 91 2002 837 844
-
(2002)
Circ Res
, vol.91
, pp. 837-844
-
-
Rossig, L.1
Li, H.2
Fisslthaler, B.3
Urbich, C.4
Fleming, I.5
Forstermann, U.6
-
118
-
-
33947520124
-
P53-induced inhibition of Hif-1 causes cardiac dysfunction during pressure overload
-
M. Sano, T. Minamino, H. Toko, H. Miyauchi, M. Orimo, and Y. Qin et al. p53-induced inhibition of Hif-1 causes cardiac dysfunction during pressure overload Nature 446 2007 444 448
-
(2007)
Nature
, vol.446
, pp. 444-448
-
-
Sano, M.1
Minamino, T.2
Toko, H.3
Miyauchi, H.4
Orimo, M.5
Qin, Y.6
-
120
-
-
79960963418
-
Mechanisms of pathological scarring: Role of myofibroblasts and current developments
-
V. Sarrazy, F. Billet, L. Micallef, B. Coulomb, and A. Desmoulière Mechanisms of pathological scarring: role of myofibroblasts and current developments Wound Repair Regen 19 2011 S10 S15
-
(2011)
Wound Repair Regen
, vol.19
-
-
Sarrazy, V.1
Billet, F.2
Micallef, L.3
Coulomb, B.4
Desmoulière, A.5
-
121
-
-
0027769876
-
A new regulatory motif in cell-cycle control causing specific inhibition of cyclin D/CDK4
-
M. Serrano, G.J. Hannon, and D. Beach A new regulatory motif in cell-cycle control causing specific inhibition of cyclin D/CDK4 Nature 366 1993 704 707
-
(1993)
Nature
, vol.366
, pp. 704-707
-
-
Serrano, M.1
Hannon, G.J.2
Beach, D.3
-
122
-
-
84883336983
-
Histone deacetylase 7 promotes Toll-like receptor 4-dependent proinflammatory gene expression in macrophages
-
M.R. Shakespear, D.M. Hohenhaus, G.M. Kelly, N.A. Kamal, P. Gupta, and L.I. Labzin et al. Histone deacetylase 7 promotes Toll-like receptor 4-dependent proinflammatory gene expression in macrophages J Biol Chem 288 2013 25362 25374
-
(2013)
J Biol Chem
, vol.288
, pp. 25362-25374
-
-
Shakespear, M.R.1
Hohenhaus, D.M.2
Kelly, G.M.3
Kamal, N.A.4
Gupta, P.5
Labzin, L.I.6
-
123
-
-
72049083765
-
Trichostatin A enhances proliferation and migration of vascular smooth muscle cells by downregulating thioredoxin 1
-
S. Song, S.W. Kang, and C. Choi Trichostatin A enhances proliferation and migration of vascular smooth muscle cells by downregulating thioredoxin 1 Cardiovasc Res 85 2010 241 249
-
(2010)
Cardiovasc Res
, vol.85
, pp. 241-249
-
-
Song, S.1
Kang, S.W.2
Choi, C.3
-
124
-
-
0033568492
-
MEF-2 function is modified by a novel co-repressor, MITR
-
D.B. Sparrow, E.A. Miska, E. Langley, S. Reynaud-Deonauth, S. Kotecha, and N. Towers et al. MEF-2 function is modified by a novel co-repressor, MITR EMBO J 18 1999 5085 5098
-
(1999)
EMBO J
, vol.18
, pp. 5085-5098
-
-
Sparrow, D.B.1
Miska, E.A.2
Langley, E.3
Reynaud-Deonauth, S.4
Kotecha, S.5
Towers, N.6
-
125
-
-
0027960448
-
Mitogen inactivation of glycogen synthase kinase-3 beta in intact cells via serine 9 phosphorylation
-
V. Stambolic, and J.R. Woodgett Mitogen inactivation of glycogen synthase kinase-3 beta in intact cells via serine 9 phosphorylation Biochem J 303 Pt 3 1994 701 704
-
(1994)
Biochem J
, vol.303
, Issue.PART 3
, pp. 701-704
-
-
Stambolic, V.1
Woodgett, J.R.2
-
126
-
-
0037044406
-
Repair of infarcted myocardium by autologous intracoronary mononuclear bone marrow cell transplantation in humans
-
B.E. Strauer, M. Brehm, T. Zeus, M. Kostering, A. Hernandez, and R.V. Sorg et al. Repair of infarcted myocardium by autologous intracoronary mononuclear bone marrow cell transplantation in humans Circulation 106 2002 1913 1918
-
(2002)
Circulation
, vol.106
, pp. 1913-1918
-
-
Strauer, B.E.1
Brehm, M.2
Zeus, T.3
Kostering, M.4
Hernandez, A.5
Sorg, R.V.6
-
128
-
-
69249155244
-
HDAC4 represses vascular endothelial growth factor expression in chondrosarcoma by modulating RUNX2 activity
-
X. Sun, L. Wei, Q. Chen, and R.M. Terek HDAC4 represses vascular endothelial growth factor expression in chondrosarcoma by modulating RUNX2 activity J Biol Chem 284 2009 21881 21890
-
(2009)
J Biol Chem
, vol.284
, pp. 21881-21890
-
-
Sun, X.1
Wei, L.2
Chen, Q.3
Terek, R.M.4
-
129
-
-
84876124887
-
Oxidative stress and chromatin remodeling in chronic obstructive pulmonary disease and smoking-related diseases
-
I.K. Sundar, H. Yao, and I. Rahman Oxidative stress and chromatin remodeling in chronic obstructive pulmonary disease and smoking-related diseases Antioxid Redox Signal 18 2013 1956 1971
-
(2013)
Antioxid Redox Signal
, vol.18
, pp. 1956-1971
-
-
Sundar, I.K.1
Yao, H.2
Rahman, I.3
-
130
-
-
44349174984
-
Identification of p300-targeted acetylated residues in GATA4 during hypertrophic responses in cardiac myocytes
-
T. Takaya, T. Kawamura, T. Morimoto, K. Ono, T. Kita, and A. Shimatsu et al. Identification of p300-targeted acetylated residues in GATA4 during hypertrophic responses in cardiac myocytes J Biol Chem 283 2008 9828 9835
-
(2008)
J Biol Chem
, vol.283
, pp. 9828-9835
-
-
Takaya, T.1
Kawamura, T.2
Morimoto, T.3
Ono, K.4
Kita, T.5
Shimatsu, A.6
-
131
-
-
0029932598
-
A mammalian histone deacetylase related to the yeast transcriptional regulator Rpd3p
-
J. Taunton, C.A. Hassig, and S.L. Schreiber A mammalian histone deacetylase related to the yeast transcriptional regulator Rpd3p Science 272 1996 408 411
-
(1996)
Science
, vol.272
, pp. 408-411
-
-
Taunton, J.1
Hassig, C.A.2
Schreiber, S.L.3
-
132
-
-
84877834926
-
Current trends in the development of histone deacetylase inhibitors: A review of recent patent applications
-
F. Thaler Current trends in the development of histone deacetylase inhibitors: a review of recent patent applications Pharm Pat Anal 1 2012 75 90
-
(2012)
Pharm Pat Anal
, vol.1
, pp. 75-90
-
-
Thaler, F.1
-
133
-
-
55549099609
-
Transgenic overexpression of Hdac3 in the heart produces increased postnatal cardiac myocyte proliferation but does not induce hypertrophy
-
C.M. Trivedi, M.M. Lu, Q. Wang, and J.A. Epstein Transgenic overexpression of Hdac3 in the heart produces increased postnatal cardiac myocyte proliferation but does not induce hypertrophy J Biol Chem 283 2008 26484 26489
-
(2008)
J Biol Chem
, vol.283
, pp. 26484-26489
-
-
Trivedi, C.M.1
Lu, M.M.2
Wang, Q.3
Epstein, J.A.4
-
134
-
-
33847695362
-
Hdac2 regulates the cardiac hypertrophic response by modulating Gsk3 beta activity
-
C.M. Trivedi, Y. Luo, Z. Yin, M. Zhang, W. Zhu, and T. Wang et al. Hdac2 regulates the cardiac hypertrophic response by modulating Gsk3 beta activity Nat Med 13 2007 324 331
-
(2007)
Nat Med
, vol.13
, pp. 324-331
-
-
Trivedi, C.M.1
Luo, Y.2
Yin, Z.3
Zhang, M.4
Zhu, W.5
Wang, T.6
-
135
-
-
77956604362
-
Hopx and Hdac2 interact to modulate Gata4 acetylation and embryonic cardiac myocyte proliferation
-
C.M. Trivedi, W. Zhu, Q. Wang, C. Jia, H.J. Kee, and L. Li et al. Hopx and Hdac2 interact to modulate Gata4 acetylation and embryonic cardiac myocyte proliferation Dev Cell 19 2010 450 459
-
(2010)
Dev Cell
, vol.19
, pp. 450-459
-
-
Trivedi, C.M.1
Zhu, W.2
Wang, Q.3
Jia, C.4
Kee, H.J.5
Li, L.6
-
136
-
-
0037199944
-
Regulation of histone deacetylase 2 by protein kinase CK2
-
S.C. Tsai, and E. Seto Regulation of histone deacetylase 2 by protein kinase CK2 J Biol Chem 277 2002 31826 31833
-
(2002)
J Biol Chem
, vol.277
, pp. 31826-31833
-
-
Tsai, S.C.1
Seto, E.2
-
137
-
-
67049145833
-
HDAC5 is a repressor of angiogenesis and determines the angiogenic gene expression pattern of endothelial cells
-
C. Urbich, L. Rossig, D. Kaluza, M. Potente, J.N. Boeckel, and A. Knau et al. HDAC5 is a repressor of angiogenesis and determines the angiogenic gene expression pattern of endothelial cells Blood 113 2009 5669 5679
-
(2009)
Blood
, vol.113
, pp. 5669-5679
-
-
Urbich, C.1
Rossig, L.2
Kaluza, D.3
Potente, M.4
Boeckel, J.N.5
Knau, A.6
-
138
-
-
84860529747
-
HDAC4 mediates development of hypertension via vascular inflammation in spontaneous hypertensive rats
-
T. Usui, M. Okada, W. Mizuno, M. Oda, N. Ide, and T. Morita et al. HDAC4 mediates development of hypertension via vascular inflammation in spontaneous hypertensive rats Am J Physiol Heart Circ Physiol 302 2012 H1894 H1904
-
(2012)
Am J Physiol Heart Circ Physiol
, vol.302
-
-
Usui, T.1
Okada, M.2
Mizuno, W.3
Oda, M.4
Ide, N.5
Morita, T.6
-
139
-
-
57349189353
-
Management of acute myocardial infarction in patients presenting with persistent ST-segment elevation: The Task Force on the Management of ST-Segment Elevation Acute Myocardial Infarction of the European Society of Cardiology
-
F. Van de Werf, J. Bax, A. Betriu, C. Blomstrom-Lundqvist, F. Crea, and V. Falk et al. Management of acute myocardial infarction in patients presenting with persistent ST-segment elevation: the Task Force on the Management of ST-Segment Elevation Acute Myocardial Infarction of the European Society of Cardiology Eur Heart J 29 2008 2909 2945
-
(2008)
Eur Heart J
, vol.29
, pp. 2909-2945
-
-
Van De Werf, F.1
Bax, J.2
Betriu, A.3
Blomstrom-Lundqvist, C.4
Crea, F.5
Falk, V.6
-
140
-
-
4544315655
-
Protein kinases C and D mediate agonist-dependent cardiac hypertrophy through nuclear export of histone deacetylase 5
-
R.B. Vega, B.C. Harrison, E. Meadows, C.R. Roberts, P.J. Papst, and E.N. Olson et al. Protein kinases C and D mediate agonist-dependent cardiac hypertrophy through nuclear export of histone deacetylase 5 Mol Cell Biol 24 2004 8374 8385
-
(2004)
Mol Cell Biol
, vol.24
, pp. 8374-8385
-
-
Vega, R.B.1
Harrison, B.C.2
Meadows, E.3
Roberts, C.R.4
Papst, P.J.5
Olson, E.N.6
-
141
-
-
0034659405
-
Active maintenance of mHDA2/mHDAC6 histone-deacetylase in the cytoplasm
-
A. Verdel, S. Curtet, M.P. Brocard, S. Rousseaux, C. Lemercier, and M. Yoshida et al. Active maintenance of mHDA2/mHDAC6 histone-deacetylase in the cytoplasm Curr Biol 10 2000 747 749
-
(2000)
Curr Biol
, vol.10
, pp. 747-749
-
-
Verdel, A.1
Curtet, S.2
Brocard, M.P.3
Rousseaux, S.4
Lemercier, C.5
Yoshida, M.6
-
142
-
-
4544323749
-
Histone deacetylase inhibitors: Understanding a new wave of anticancer agents
-
A. Villar-Garea, and M. Esteller Histone deacetylase inhibitors: understanding a new wave of anticancer agents Int J Cancer 112 2004 171 178
-
(2004)
Int J Cancer
, vol.112
, pp. 171-178
-
-
Villar-Garea, A.1
Esteller, M.2
-
143
-
-
70350278896
-
Histone deacetylases 1 and 2 are phosphorylated at novel sites during varicella-zoster virus infection
-
M.S. Walters, A. Erazo, P.R. Kinchington, and S. Silverstein Histone deacetylases 1 and 2 are phosphorylated at novel sites during varicella-zoster virus infection J Virol 83 2009 11502 11513
-
(2009)
J Virol
, vol.83
, pp. 11502-11513
-
-
Walters, M.S.1
Erazo, A.2
Kinchington, P.R.3
Silverstein, S.4
-
144
-
-
77950986508
-
Fluid shear stress stimulates phosphorylation-dependent nuclear export of HDAC5 and mediates expression of KLF2 and eNOS
-
W. Wang, C.H. Ha, B.S. Jhun, C. Wong, M.K. Jain, and Z.G. Jin Fluid shear stress stimulates phosphorylation-dependent nuclear export of HDAC5 and mediates expression of KLF2 and eNOS Blood 115 2010 2971 2979
-
(2010)
Blood
, vol.115
, pp. 2971-2979
-
-
Wang, W.1
Ha, C.H.2
Jhun, B.S.3
Wong, C.4
Jain, M.K.5
Jin, Z.G.6
-
145
-
-
84865595109
-
Chronic valproate treatment enhances postischemic angiogenesis and promotes functional recovery in a rat model of ischemic stroke
-
Z. Wang, L.K. Tsai, J. Munasinghe, Y. Leng, E.B. Fessler, and F. Chibane et al. Chronic valproate treatment enhances postischemic angiogenesis and promotes functional recovery in a rat model of ischemic stroke Stroke 43 2012 2430 2436
-
(2012)
Stroke
, vol.43
, pp. 2430-2436
-
-
Wang, Z.1
Tsai, L.K.2
Munasinghe, J.3
Leng, Y.4
Fessler, E.B.5
Chibane, F.6
-
146
-
-
0346688568
-
Altered interaction of HDAC5 with GATA-1 during MEL cell differentiation
-
K. Watamoto, M. Towatari, Y. Ozawa, Y. Miyata, M. Okamoto, and A. Abe et al. Altered interaction of HDAC5 with GATA-1 during MEL cell differentiation Oncogene 22 2003 9176 9184
-
(2003)
Oncogene
, vol.22
, pp. 9176-9184
-
-
Watamoto, K.1
Towatari, M.2
Ozawa, Y.3
Miyata, Y.4
Okamoto, M.5
Abe, A.6
-
147
-
-
4344565788
-
GATA4 is essential for formation of the proepicardium and regulates cardiogenesis
-
A.J. Watt, M.A. Battle, J. Li, and S.A. Duncan GATA4 is essential for formation of the proepicardium and regulates cardiogenesis Proc Natl Acad Sci U S A 101 2004 12573 12578
-
(2004)
Proc Natl Acad Sci U S A
, vol.101
, pp. 12573-12578
-
-
Watt, A.J.1
Battle, M.A.2
Li, J.3
Duncan, S.A.4
-
148
-
-
0037382574
-
Human Sin3 deacetylase and trithorax-related Set1/Ash2 histone H3-K4 methyltransferase are tethered together selectively by the cell-proliferation factor HCF-1
-
J. Wysocka, M.P. Myers, C.D. Laherty, R.N. Eisenman, and W. Herr Human Sin3 deacetylase and trithorax-related Set1/Ash2 histone H3-K4 methyltransferase are tethered together selectively by the cell-proliferation factor HCF-1 Genes Dev 17 2003 896 911
-
(2003)
Genes Dev
, vol.17
, pp. 896-911
-
-
Wysocka, J.1
Myers, M.P.2
Laherty, C.D.3
Eisenman, R.N.4
Herr, W.5
-
149
-
-
34547864236
-
Histone deacetylase inhibitors: Molecular mechanisms of action
-
W.S. Xu, R.B. Parmigiani, and P.A. Marks Histone deacetylase inhibitors: molecular mechanisms of action Oncogene 26 2007 5541 5552
-
(2007)
Oncogene
, vol.26
, pp. 5541-5552
-
-
Xu, W.S.1
Parmigiani, R.B.2
Marks, P.A.3
-
150
-
-
39749127166
-
The Rpd3/Hda1 family of lysine deacetylases: From bacteria and yeast to mice and men
-
X.J. Yang, and E. Seto The Rpd3/Hda1 family of lysine deacetylases: from bacteria and yeast to mice and men Nat Rev Mol Cell Biol 9 2008 206 218
-
(2008)
Nat Rev Mol Cell Biol
, vol.9
, pp. 206-218
-
-
Yang, X.J.1
Seto, E.2
-
151
-
-
48249113711
-
Conditional deletion of Kruppel-like factor 4 delays downregulation of smooth muscle cell differentiation markers but accelerates neointimal formation following vascular injury
-
T. Yoshida, K.H. Kaestner, and G.K. Owens Conditional deletion of Kruppel-like factor 4 delays downregulation of smooth muscle cell differentiation markers but accelerates neointimal formation following vascular injury Circ Res 102 2008 1548 1557
-
(2008)
Circ Res
, vol.102
, pp. 1548-1557
-
-
Yoshida, T.1
Kaestner, K.H.2
Owens, G.K.3
-
152
-
-
74549187447
-
Histone deacetylase 3 is critical in endothelial survival and atherosclerosis development in response to disturbed flow
-
A. Zampetaki, L. Zeng, A. Margariti, Q. Xiao, H. Li, and Z. Zhang et al. Histone deacetylase 3 is critical in endothelial survival and atherosclerosis development in response to disturbed flow Circulation 121 2010 132 142
-
(2010)
Circulation
, vol.121
, pp. 132-142
-
-
Zampetaki, A.1
Zeng, L.2
Margariti, A.3
Xiao, Q.4
Li, H.5
Zhang, Z.6
-
153
-
-
84873961120
-
Inhibition of histone deacetylase-induced myocardial repair is mediated by c-kit in infarcted hearts
-
L. Zhang, B. Chen, Y. Zhao, P.M. Dubielecka, L. Wei, and G.J. Qin et al. Inhibition of histone deacetylase-induced myocardial repair is mediated by c-kit in infarcted hearts J Biol Chem 287 2012 39338 39348
-
(2012)
J Biol Chem
, vol.287
, pp. 39338-39348
-
-
Zhang, L.1
Chen, B.2
Zhao, Y.3
Dubielecka, P.M.4
Wei, L.5
Qin, G.J.6
-
154
-
-
0037162697
-
Class II histone deacetylases act as signal-responsive repressors of cardiac hypertrophy
-
C.L. Zhang, T.A. McKinsey, S. Chang, C.L. Antos, J.A. Hill, and E.N. Olson Class II histone deacetylases act as signal-responsive repressors of cardiac hypertrophy Cell 110 2002 479 488
-
(2002)
Cell
, vol.110
, pp. 479-488
-
-
Zhang, C.L.1
McKinsey, T.A.2
Chang, S.3
Antos, C.L.4
Hill, J.A.5
Olson, E.N.6
-
155
-
-
84863349101
-
Inhibition of histone deacetylases preserves myocardial performance and prevents cardiac remodeling through stimulation of endogenous angiomyogenesis
-
L. Zhang, X. Qin, Y. Zhao, L. Fast, S. Zhuang, and P. Liu et al. Inhibition of histone deacetylases preserves myocardial performance and prevents cardiac remodeling through stimulation of endogenous angiomyogenesis J Pharmacol Exp Ther 341 2012 285 293
-
(2012)
J Pharmacol Exp Ther
, vol.341
, pp. 285-293
-
-
Zhang, L.1
Qin, X.2
Zhao, Y.3
Fast, L.4
Zhuang, S.5
Liu, P.6
-
156
-
-
35548942629
-
Inhibition of histone deacetylases triggers pharmacologic preconditioning effects against myocardial ischemic injury
-
T.C. Zhao, G. Cheng, L.X. Zhang, Y.T. Tseng, and J.F. Padbury Inhibition of histone deacetylases triggers pharmacologic preconditioning effects against myocardial ischemic injury Cardiovasc Res 76 2007 473 481
-
(2007)
Cardiovasc Res
, vol.76
, pp. 473-481
-
-
Zhao, T.C.1
Cheng, G.2
Zhang, L.X.3
Tseng, Y.T.4
Padbury, J.F.5
-
157
-
-
73349084646
-
Inpp5f is a polyphosphoinositide phosphatase that regulates cardiac hypertrophic responsiveness
-
W. Zhu, C.M. Trivedi, D. Zhou, L. Yuan, M.M. Lu, and J.A. Epstein Inpp5f is a polyphosphoinositide phosphatase that regulates cardiac hypertrophic responsiveness Circ Res 105 2009 1240 1247
-
(2009)
Circ Res
, vol.105
, pp. 1240-1247
-
-
Zhu, W.1
Trivedi, C.M.2
Zhou, D.3
Yuan, L.4
Lu, M.M.5
Epstein, J.A.6
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