Class IIb HDAC6 regulates endothelial cell migration and angiogenesis by deacetylation of cortactin

EMBO Journal

Volumn 30, Issue 20, 2011, Pages 4142-4156

  Kaluza, David ^a   Kroll, Jens ^b,c   Gesierich, Sabine ^c   Yao, Tso Pang ^d   Boon, Reinier A ^a   Hergenreider, Eduard ^a   Tjwa, Marc ^a   Rössig, Lothar ^a   Seto, Edward ^e   Augustin, Hellmut G ^b,c   Zeiher, Andreas M ^a   Dimmeler, Stefanie ^a   Urbich, Carmen ^a  

^a GOETHE UNIVERSITY   (Germany)

^b Centre for Biomedicine and Medical Technology   (Germany)

^c GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

^d DUKE UNIVERSITY MEDICAL CENTER   (United States)

^e H LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE   (United States)

Author keywords

angiogenesis; cortactin; deacetylation; endothelial cells; histone deacetylases

Indexed keywords

ALPHA TUBULIN; CORTACTIN; HISTONE DEACETYLASE 6; MESSENGER RNA; UBIQUITIN;

ANGIOGENESIS; ARTICLE; CATALYSIS; CELL MIGRATION; DEACETYLATION; EMBRYO DEVELOPMENT; GENE SILENCING; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; MOUSE; NERVE SPROUTING; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN FUNCTION; UMBILICAL VEIN ENDOTHELIAL CELL; UPREGULATION; WILD TYPE; ZEBRA FISH;

ACETYLATION; ANIMALS; CARCINOMA, LEWIS LUNG; CELL MOVEMENT; CELLS, CULTURED; CORTACTIN; ENDOTHELIAL CELLS; FEMALE; HISTONE DEACETYLASES; HUMANS; LUNG NEOPLASMS; MALE; MICE; MICE, KNOCKOUT; NEOVASCULARIZATION, PHYSIOLOGIC; TUBULIN; ZEBRAFISH PROTEINS;

DANIO RERIO; MUS;

EID: 80054881600     PISSN: 02614189     EISSN: 14602075     Source Type: Journal    
DOI: 10.1038/emboj.2011.298     Document Type: Article

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