Class II histone deacetylases act as signal-responsive repressors of cardiac hypertrophy

Cell

Volumn 110, Issue 4, 2002, Pages 479-488

  Zhang, Chun Li ^a   McKinsey, Timothy A ^a   Chang, Shurong ^a   Antos, Christopher L ^a   Hill, Joseph A ^b   Olson, Eric N ^a  

^a UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^b UNIVERSITY OF IOWA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

HISTONE DEACETYLASE; MYOCYTE ENHANCER FACTOR 2; SERINE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ENZYME SPECIFICITY; GENE EXPRESSION; HEART FAILURE; HEART VENTRICLE HYPERTROPHY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN INTERACTION; STRESS;

ANIMALIA;

EID: 0037162697     PISSN: 00928674     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0092-8674(02)00861-9     Document Type: Article

References (29)

1. Black B.L., Olson E.N. Transcriptional control of muscle development by myocyte enhancer factor-2 (MEF2) proteins. Annu. Rev. Cell Dev. Biol. 14:1998;167-196.
2. Chien K.R. Stress pathways and heart failure. Cell. 98:1999;555-558.
3. Frey N., McKinsey T.A., Olson E.N. Decoding calcium signals involved in cardiac growth and function. Nat. Med. 6:2000;1221-1227.
4. Grozinger C.M., Schreiber S.L. Regulation of histone deacetylase 4 and 5 and transcriptional activity by 14-3-3-dependent cellular localization. Proc. Natl. Acad. Sci. USA. 97:2000;7835-7840.
5. Grozinger C.M., Schreiber S.L. Deacetylase enzymes. Biological functions and the use of small-molecule inhibitors. Chem. Biol. 9:2002;3-16.
6. Hill J.A., Karimi M., Kutschke W., Davisson R.L., Zimmerman K., Wang Z., Kerber R.E., Weiss R.M. Cardiac hypertrophy is not a required compensatory response to short-term pressure overload. Circulation. 101:2000;2863-2869.
7. Impey S., Fong A.L., Wang Y., Cardinaux J.R., Fass D.M., Obrietan K., Wayman G.A., Storm D.R., Soderling T.R., Goodman R.H. Phosphorylation of CBP mediates transcriptional activation by neural activity and CaM kinase IV. Neuron. 34:2002;235-244.
8. Jenuwein T., Allis C.D. Translating the histone code. Science. 293:2001;1074-1080.
9. Johnson C.A., Turner B.M. Histone deacetylases. complex transducers of nuclear signals Semin. Cell Dev. Biol. 10:1999;179-188.
10. Kato T., Sano M., Miyoshi S., Sato T., Hakuno D., Ishida H., Kinoshita-Nakazawa H., Fukuda K., Ogawa S. Calmodulin kinases II and IV and calcineurin are involved in leukemia inhibitory factor-induced cardiac hypertrophy in rats. Circ. Res. 87:2000;937-945.
11. Kirchhefer U., Schmitz W., Scholz H., Neumann J. Activity of cAMP-dependent protein kinase and Ca2+/calmodulin-dependent protein kinase in failing and nonfailing human hearts. Cardiovasc. Res. 42:1999;254-261.
12. Liang Q., De Windt L.J., Witt S.A., Kimball T.R., Markham B.E., Molkentin J.D. The transcription factors GATA4 and GATA6 regulate cardiomyocyte hypertrophy in vitro and in vivo. J. Biol. Chem. 276:2001;30245-30253.
13. Lowes B.D., Gilbert E.M., Abraham W.T., Minobe W.A., Larrabee P., Ferguson D., Wolfel E.E., Lindenfeld J., Tsvetkova T., Robertson A.D.et al. Myocardial gene expression in dilated cardiomyopathy treated with beta-blocking agents. N. Engl. J. Med. 346:2002;1357-1365.
14. Lu J., McKinsey T.A., Nicol R.L., Olson E.N. Signal-dependent activation of the MEF2 transcription factor by dissociation from histone deacetylases. Proc. Natl. Acad. Sci. USA. 97:2000;4070-4075. a.
15. Lu J., McKinsey T.A., Zhang C.L., Olson E.N. Regulation of skeletal myogenesis by association of the MEF2 transcription factor with class II histone deacetylases. Mol. Cell. 6:2000;233-244. b.
16. McKinsey T.A., Zhang C.L., Lu J., Olson E.N. Signal-dependent nuclear export of a histone deacetylase regulates muscle differentiation. Nature. 408:2000;106-111. a.
17. McKinsey T.A., Zhang C.L., Olson E.N. Activation of the myocyte enhancer factor-2 transcription factor by calcium/calmodulin-dependent protein kinase-stimulated binding of 14-3-3 to histone deacetylase 5. Proc. Natl. Acad. Sci. USA. 97:2000;14400-14405. b.
18. McKinsey T.A., Zhang C.L., Olson E.N. MEF2. a calcium-dependent regulator of cell division, differentiation and death Trends Biochem. Sci. 27:2002;40-47.
19. Molkentin J.D., Lu J.R., Antos C.L., Markham B., Richardson J., Robbins J., Grant S.R., Olson E.N. A calcineurin-dependent transcriptional pathway for cardiac hypertrophy. Cell. 93:1998;215-228.
20. Morin S., Charron F., Robitaille L., Nemer M. GATA-dependent recruitment of MEF2 proteins to target promoters. EMBO J. 19:2000;2046-2055.
21. Naya F.J., Wu C., Richardson J.A., Overbeek P., Olson E.N. Transcriptional activity of MEF2 during mouse embryogenesis monitored with a MEF2-dependent transgene. Development. 126:1999;2045-2052.
22. Passier R., Zeng H., Frey N., Naya F.J., Nicol R.L., McKinsey T.A., Overbeek P., Richardson J.A., Grant S.R., Olson E.N. CaM kinase signaling induces cardiac hypertrophy and activates the MEF2 transcription factor in vivo. J. Clin. Invest. 105:2000;1395-1406.
23. Sartorelli V., Huang J., Hamamori Y., Kedes L. Molecular mechanisms of myogenic coactivation by p300. direct interaction with the activation domain of MyoD and with the MADS box of MEF2C Mol. Cell. Biol. 17:1997;1010-1026.
24. Sparrow D.B., Miska E.A., Langley E., Reynaud-Deonauth S., Kotecha S., Towers N., Spohr G., Kouzarides T., Mohun T.J. MEF-2 function is modified by a novel co-repressor, MITR. EMBO J. 18:1999;5085-5098.
25. Youn H.D., Chatila T.A., Liu J.O. Integration of calcineurin and MEF2 signals by the coactivator p300 during T-cell apoptosis. EMBO J. 19:2000;4323-4331.
26. Zhang C.L., McKinsey T.A., Lu J.R., Olson E.N. Association of COOH-terminal-binding protein (CtBP) and MEF2-interacting transcription repressor (MITR) contributes to transcriptional repression of the MEF2 transcription factor. J. Biol. Chem. 276:2001;35-39. a.
27. Zhang C.L., McKinsey T.A., Olson E.N. The transcriptional corepressor MITR is a signal-responsive inhibitor of myogenesis. Proc. Natl. Acad. Sci. USA. 98:2001;7354-7359. b.
28. Zhang T., Johnson E.N., Gu Y., Morissette M.R., Sah V.P., Gigena M.S., Belke D.D., Dillmann W.H., Rogers T.B., Schulman H.et al. The cardiac-specific nuclear δ(B) isoform of Ca2+/calmodulin-dependent protein kinase II induces hypertrophy and dilated cardiomyopathy associated with increased protein phosphatase 2A activity. J. Biol. Chem. 277:2002;1261-1267.
29. Zhou X., Marks P.A., Rifkind R.A., Richon V.M. Cloning and characterization of a histone deacetylase, HDAC9. Proc. Natl. Acad. Sci. USA. 98:2001;10572-10577.