Krüppel-like factor 4 mediates histone deacetylase inhibitor-induced prevention of cardiac hypertrophy

Journal of Molecular and Cellular Cardiology

Volumn 47, Issue 6, 2009, Pages 770-780

  Kee, Hae Jin ^a   Kook, Hyun ^a  

^a Chonnam National University Medical School   (South Korea)

Author keywords

Cardiac hypertrophy; Class I histone deacetylases; Histone deacetylase inhibitor; Kr ppel like factor 4; Rat neonatal cardiomyocyte

Indexed keywords

HISTONE DEACETYLASE INHIBITOR; KRUPPEL LIKE FACTOR 4; MYOSIN HEAVY POLYPEPTIDE 7; NATRIURETIC POLYPEPTIDE PRECURSOR TYPE A; PHENYLEPHRINE; POLYPEPTIDE; SK 7041; TRICHOSTATIN A; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; DOWN REGULATION; DRUG MECHANISM; DRUG TARGETING; GENE REPRESSION; HEART HYPERTROPHY; HEART PROTECTION; HUMAN; HUMAN CELL; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN BINDING; PROTEIN FUNCTION; UPREGULATION;

ANIMALS; ANIMALS, NEWBORN; ATRIAL NATRIURETIC FACTOR; CARDIOMEGALY; DOWN-REGULATION; GENE KNOCKDOWN TECHNIQUES; HISTONE DEACETYLASE INHIBITORS; KRUPPEL-LIKE TRANSCRIPTION FACTORS; PHENOTYPE; PROTEIN BINDING; RATS; RESPONSE ELEMENTS; STRESS, PHYSIOLOGICAL;

MUS; RATTUS;

EID: 70449095895     PISSN: 00222828     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.yjmcc.2009.08.022     Document Type: Article

References (31)

1. Pearson R., Fleetwood J., Eaton S., Crossley M., and Bao S. Kruppel-like transcription factors: a functional family. Int. J. Biochem. Cell Biol. 40 10 (2008) 1996-2001
2. Evans P.M., and Liu C. Roles of Kruppel-like factor 4 in normal homeostasis, cancer and stem cells. Acta Biochim. Biophys. Sin. (Shanghai) 40 7 (2008) 554-564
3. Katz J.P., Perreault N., Goldstein B.G., Lee C.S., Labosky P.A., Yang V.W., et al. The zinc-finger transcription factor Klf4 is required for terminal differentiation of goblet cells in the colon. Development 129 11 (2002) 2619-2628
4. Segre J.A., Bauer C., and Fuchs E. Klf4 is a transcription factor required for establishing the barrier function of the skin. Nat. Genet. 22 4 (1999) 356-360
5. Takahashi K., and Yamanaka S. Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors. Cell 126 4 (2006) 663-676
6. Zhang W., Geiman D.E., Shields J.M., Dang D.T., Mahatan C.S., Kaestner K.H., et al. The gut-enriched Kruppel-like factor (Kruppel-like factor 4) mediates the transactivating effect of p53 on the p21WAF1/Cip1 promoter. J. Biol. Chem. 275 24 (2000) 18391-18398
7. Shie J.L., Chen Z.Y., Fu M., Pestell R.G., and Tseng C.C. Gut-enriched Kruppel-like factor represses cyclin D1 promoter activity through Sp1 motif. Nucleic Acids Res. 28 15 (2000) 2969-2976
8. Backs J., and Olson E.N. Control of cardiac growth by histone acetylation/deacetylation. Circ. Res. 98 1 (2006) 15-24
9. Zhang C.L., McKinsey T.A., Chang S., Antos C.L., Hill J.A., and Olson E.N. Class II histone deacetylases act as signal-responsive repressors of cardiac hypertrophy. Cell 110 4 (2002) 479-488
10. Trivedi C.M., Luo Y., Yin Z., Zhang M., Zhu W., Wang T., et al. Hdac2 regulates the cardiac hypertrophic response by modulating Gsk3 beta activity. Nat. Med. 13 3 (2007) 324-331
11. Haberland M., Montgomery R.L., and Olson E.N. The many roles of histone deacetylases in development and physiology: implications for disease and therapy. Nat. Rev. Genet. 10 1 (2009) 32-42
12. Kee H.J., Sohn I.S., Nam K.I., Park J.E., Qian Y.R., Yin Z., et al. Inhibition of histone deacetylation blocks cardiac hypertrophy induced by angiotensin II infusion and aortic banding. Circulation 113 1 (2006) 51-59
13. Kong Y., Tannous P., Lu G., Berenji K., Rothermel B.A., Olson E.N., et al. Suppression of class I and II histone deacetylases blunts pressure-overload cardiac hypertrophy. Circulation 113 22 (2006) 2579-2588
14. Kee H.J., Eom G.H., Joung H., Shin S., Kim J.R., Cho Y.K., et al. Activation of histone deacetylase 2 by inducible heat shock protein 70 in cardiac hypertrophy. Circ. Res. 103 11 (2008) 1259-1269
15. Liu T., Tee A.E., Porro A., Smith S.A., Dwarte T., Liu P.Y., et al. Activation of tissue transglutaminase transcription by histone deacetylase inhibition as a therapeutic approach for Myc oncogenesis. Proc. Natl. Acad. Sci. U. S. A. 104 47 (2007) 18682-18687
16. Houweling A.C., van Borren M.M., Moorman A.F., and Christoffels V.M. Expression and regulation of the atrial natriuretic factor encoding gene Nppa during development and disease. Cardiovasc. Res. 67 4 (2005) 583-593
17. Humphrey G.W., Wang Y.H., Hirai T., Padmanabhan R., Panchision D.M., Newell L.F., et al. Complementary roles for histone deacetylases 1, 2, and 3 in differentiation of pluripotent stem cells. Differentiation 76 4 (2008) 348-356
18. Hsi L.C., Xi X., Lotan R., Shureiqi I., and Lippman S.M. The histone deacetylase inhibitor suberoylanilide hydroxamic acid induces apoptosis via induction of 15-lipoxygenase-1 in colorectal cancer cells. Cancer Res. 64 23 (2004) 8778-8781
19. Antos C.L., McKinsey T.A., Dreitz M., Hollingsworth L.M., Zhang C.L., Schreiber K., et al. Dose-dependent blockade to cardiomyocyte hypertrophy by histone deacetylase inhibitors. J. Biol. Chem. 278 31 (2003) 28930-28937
20. Kuwahara K., Saito Y., Ogawa E., Takahashi N., Nakagawa Y., Naruse Y., et al. The neuron-restrictive silencer element-neuron-restrictive silencer factor system regulates basal and endothelin 1-inducible atrial natriuretic peptide gene expression in ventricular myocytes. Mol. Cell Biol. 21 6 (2001) 2085-2097
21. Chen Z.Y., Rex S., and Tseng C.C. Kruppel-like factor 4 is transactivated by butyrate in colon cancer cells. J. Nutr. 134 4 (2004) 792-798
22. Davie J.R. Inhibition of histone deacetylase activity by butyrate. J. Nutr. 133 7 Suppl. (2003) 2485S-2493S
23. Cullingford T.E., Butler M.J., Marshall A.K., Tham el L., Sugden P.H., and Clerk A. Differential regulation of Kruppel-like factor family transcription factor expression in neonatal rat cardiac myocytes: effects of endothelin-1, oxidative stress and cytokines. Biochim. Biophys. Acta 1783 6 (2008) 1229-1236
24. Shindo T., Manabe I., Fukushima Y., Tobe K., Aizawa K., Miyamoto S., et al. Kruppel-like zinc-finger transcription factor KLF5/BTEB2 is a target for angiotensin II signaling and an essential regulator of cardiovascular remodeling. Nat. Med. 8 8 (2002) 856-863
25. Rajamannan N.M., Subramaniam M., Abraham T.P., Vasile V.C., Ackerman M.J., Monroe D.G., et al. TGFbeta inducible early gene-1 (TIEG1) and cardiac hypertrophy: discovery and characterization of a novel signaling pathway. J. Cell Biochem. 100 2 (2007) 315-325
26. Fisch S., Gray S., Heymans S., Haldar S.M., Wang B., Pfister O., et al. Kruppel-like factor 15 is a regulator of cardiomyocyte hypertrophy. Proc. Natl. Acad. Sci. U. S. A. 104 17 (2007) 7074-7079
27. Otteson D.C., Lai H., Liu Y., and Zack D.J. Zinc-finger domains of the transcriptional repressor KLF15 bind multiple sites in rhodopsin and IRBP promoters including the CRS-1 and G-rich repressor elements. BMC Mol. Biol. 6 (2005) 15
28. Liu Y., Sinha S., McDonald O.G., Shang Y., Hoofnagle M.H., and Owens G.K. Kruppel-like factor 4 abrogates myocardin-induced activation of smooth muscle gene expression. J. Biol. Chem. 280 10 (2005) 9719-9727
29. Yoshida T., Kaestner K.H., and Owens G.K. Conditional deletion of Kruppel-like factor 4 delays downregulation of smooth muscle cell differentiation markers but accelerates neointimal formation following vascular injury. Circ. Res. 102 12 (2008) 1548-1557
30. Michel J.B., Arnal J.F., and Corvol P. Atrial natriuretic factor as a marker in congestive heart failure. Horm. Res. 34 3-4 (1990) 166-168
31. Hauck L., Harms C., An J., Rohne J., Gertz K., Dietz R., et al. Protein kinase CK2 links extracellular growth factor signaling with the control of p27(Kip1) stability in the heart. Nat. Med. 14 3 (2008) 315-324