Acute β-adrenergic activation triggers nuclear import of histone deacetylase 5 and delays Gq-induced transcriptional activation

Journal of Biological Chemistry

Volumn 288, Issue 1, 2013, Pages 192-204

  Chang, Chia Wei Jenny ^a,b   Lee, Linda ^a   Yu, David ^a   Dao, Khanha ^a   Bossuyt, Julie ^a   Bers, Donald M ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b LOYOLA UNIVERSITY CHICAGO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADRENERGIC RECEPTORS; CARDIAC MYOCYTES; CARDIAC REMODELING; CO-ACTIVATION; COUPLED RECEPTORS; DYNAMIC REGULATION; EPIGENETIC CONTROL; HEART FAILURE; HISTONE DEACETYLASES; ISOPROTERENOL; MYOCYTES; NUCLEAR ACCUMULATION; NUCLEAR EXPORT; NUCLEAR IMPORT; NUCLEO-CYTOPLASMIC SHUTTLING; PHYSIOLOGICAL CONTROL; PROTEIN KINASE; RABBIT MODELS; TRANSCRIPTIONAL ACTIVATIONS; TRANSCRIPTIONAL REPRESSORS; WILD TYPES;

CALMODULIN; CARDIOLOGY; ENZYMES; PHOSPHORYLATION;

SIGNALING;

BETA ADRENERGIC RECEPTOR; BETA ADRENERGIC RECEPTOR STIMULATING AGENT; CALCIUM CALMODULIN DEPENDENT PROTEIN KINASE II; CELL RECEPTOR; CYCLIC AMP DEPENDENT PROTEIN KINASE; GQ COUPLED RECEPTOR; HISTONE DEACETYLASE 5; ISOPRENALINE; PROTEIN KINASE D; SERINE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BETA ADRENERGIC STIMULATION; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME REGULATION; HEART FAILURE; MALE; MUSCLE CELL; NONHUMAN; NUCLEAR EXPORT; NUCLEAR IMPORT; NUCLEOCYTOPLASMIC TRANSPORT; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; RABBIT; RAT; SIGNAL TRANSDUCTION; TRANSCRIPTION INITIATION;

ACTIVE TRANSPORT, CELL NUCLEUS; ANIMALS; CALCIUM-CALMODULIN-DEPENDENT PROTEIN KINASE TYPE 2; CYCLIC AMP-DEPENDENT PROTEIN KINASES; GENE EXPRESSION REGULATION; GTP-BINDING PROTEIN ALPHA SUBUNITS, GQ-G11; HEMODYNAMICS; HISTONE DEACETYLASES; MALE; MICROSCOPY, CONFOCAL; MODELS, BIOLOGICAL; MUSCLE CELLS; MUTATION; PHOSPHORYLATION; PROTEIN BINDING; PROTEIN KINASE C; RABBITS; RATS; RECEPTORS, ADRENERGIC, BETA; SIGNAL TRANSDUCTION; TRANSCRIPTIONAL ACTIVATION;

ORYCTOLAGUS CUNICULUS;

EID: 84872055680     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.382358     Document Type: Article

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