-
1
-
-
0034663835
-
Occupational and environmental risk factors for idiopathic pulmonary fibrosis: A multicenter case-control study
-
DOI 10.1093/aje/152.4.307
-
Baumgartner KB, Samet JM, Coultas DB, et al. Occupational and environmental risk factors for idiopathic pulmonary fibrosis: A multicenter case-control study. Collaborating Centers. Am J Epidemiol 2000;152:307-15 (Pubitemid 30626724
-
(2000)
American Journal of Epidemiology
, vol.152
, Issue.4
, pp. 307-315
-
-
Baumgartner, K.B.1
Samet, J.M.2
Coultas, D.B.3
Stidley, C.A.4
Hunt, W.C.5
Colby, T.V.6
Waldron, J.A.7
Baughman, R.8
Davis, G.S.9
Garcia, J.G.N.10
Hunningshake, G.W.11
Kallay, M.C.12
King Jr., T.E.13
Krowka, M.J.14
Rennard, S.I.15
Ryu, J.H.16
Sherman, C.B.17
Smith, L.J.18
Toews, G.19
Winterbauer, R.H.20
more..
-
2
-
-
0041874992
-
Changes in clinical and physiologic variables predict survival in idiopathic pulmonary fibrosis
-
DOI 10.1164/rccm.200211-1311OC
-
Collard HR, King TE Jr, Bartelson BB, et al. Changes in clinical and physiologic variables predict survival in idiopathic pulmonary fibrosis. Am J Respir Crit Care Med 2003;168:538-42 (Pubitemid 37088595
-
(2003)
American Journal of Respiratory and Critical Care Medicine
, vol.168
, Issue.5
, pp. 538-542
-
-
Collard, H.R.1
King Jr., T.E.2
Bartelson, B.B.3
Vourlekis, J.S.4
Schwarz, M.I.5
Brown, K.K.6
-
3
-
-
33749444308
-
Incidence and prevalence of idiopathic pulmonary fibrosis
-
DOI 10.1164/rccm.200602-163OC
-
Raghu G, Weycker D, Edelsberg J, et al. Incidence and prevalence of idiopathic pulmonary fibrosis. Am J Respir Crit Care Med 2006;174:810-16 (Pubitemid 44511663
-
(2006)
American Journal of Respiratory and Critical Care Medicine
, vol.174
, Issue.7
, pp. 810-816
-
-
Raghu, G.1
Weycker, D.2
Edelsberg, J.3
Bradford, W.Z.4
Oster, G.5
-
4
-
-
79951844263
-
Clinical course and prediction of survival in idiopathic pulmonary fibrosis
-
Ley B, Collard HR, King TE Jr. Clinical course and prediction of survival in idiopathic pulmonary fibrosis. Am J Respir Crit Care Med 2011;183:431-40
-
(2011)
Am J Respir Crit Care Med
, vol.183
, pp. 431-440
-
-
Ley, B.1
Collard, H.R.2
King Jr., T.E.3
-
5
-
-
0034011982
-
Idiopathic pulmonary fibrosis: Diagnosis and treatment. International consensus statement. American Thoracic Society (ATS), and the European Respiratory Society (ERS)
-
No authors listed American Thoracic Society
-
No authors listed American Thoracic Society. Idiopathic pulmonary fibrosis: Diagnosis and treatment. International consensus statement. American Thoracic Society (ATS), and the European Respiratory Society (ERS). Am J Respir Crit Care Med 2000;161:646-64
-
(2000)
Am J Respir Crit Care Med
, vol.161
, pp. 646-664
-
-
-
6
-
-
10744220627
-
Radiologic Findings Are Strongly Associated with a Pathologic Diagnosis of Usual Interstitial Pneumonia
-
DOI 10.1378/chest.124.4.1215
-
Hunninghake GW, Lynch DA, Galvin JR, et al. Radiologic findings are strongly associated with a pathologic diagnosis of usual interstitial pneumonia. Chest 2003;124:1215-23 (Pubitemid 37290029
-
(2003)
Chest
, vol.124
, Issue.4
, pp. 1215-1223
-
-
Hunninghake, G.W.1
Lynch, D.A.2
Galvin, J.R.3
Gross, B.H.4
Muller, N.5
Schwartz, D.A.6
King Jr., T.E.7
Lynch III, J.P.8
Hegele, R.9
Waldron, J.10
Colby, T.V.11
Hogg, J.C.12
-
7
-
-
0035508478
-
Histopathologic variability in usual and nonspecific interstitial pneumonias
-
Flaherty KR, Travis WD, Colby TV, et al. Histopathologic variability in usual and nonspecific interstitial pneumonias. Am J Respir Crit Care Med 2001;164:1722-7 (Pubitemid 33124165
-
(2001)
American Journal of Respiratory and Critical Care Medicine
, vol.164
, Issue.9
, pp. 1722-1727
-
-
Flaherty, K.R.1
Travis, W.D.2
Colby, T.V.3
Toews, G.B.4
Kazerooni, E.A.5
Gross, B.H.6
Jain, A.7
Strawderman III, R.L.8
Flint, A.9
Lynch III, J.P.10
Martinez, F.J.11
-
8
-
-
0031965748
-
Idiopathic pulmonary fibrosis: Clinical relevance of pathologic classification
-
Katzenstein AL, Myers JL. Idiopathic pulmonary fibrosis: Clinical relevance of pathologic classification. Am J Respir Crit Care Med 1998;157:1301-15
-
(1998)
Am J Respir Crit Care Med
, vol.157
, pp. 1301-1315
-
-
Katzenstein, A.L.1
Myers, J.L.2
-
9
-
-
0035895243
-
Idiopathic pulmonary fibrosis: Prevailing and evolving hypotheses about its pathogenesis and implications for therapy
-
Selman M, King TE, Pardo A. Idiopathic pulmonary fibrosis: Prevailing and evolving hypotheses about its pathogenesis and implications for therapy. Ann Intern Med 2001;134:136-51 (Pubitemid 32096342
-
(2001)
Annals of Internal Medicine
, vol.134
, Issue.2
, pp. 136-151
-
-
Selman, M.1
King Jr., T.E.2
Pardo, A.3
-
10
-
-
0029995678
-
Corticosteroids and the treatment idiopathic pulmonary fibrosis: Past, present, and future
-
Mapel DW, Samet JM, Coultas DB. Corticosteroids and the treatment of idiopathic pulmonary fibrosis: Past, present, and future. Chest 1996;110:1058-67 (Pubitemid 26347626
-
(1996)
Chest
, vol.110
, Issue.4
, pp. 1058-1067
-
-
Mapel, D.W.1
Samet, J.M.2
Coultas, D.B.3
-
11
-
-
84876706037
-
A review of current and novel therapies for idiopathic pulmonary fibrosis
-
Rafii R, Juarez MM, Albertson TE, Chan AL. A review of current and novel therapies for idiopathic pulmonary fibrosis. J Thorac Dis 2013;5:48-73
-
(2013)
J Thorac Dis
, vol.5
, pp. 48-73
-
-
Rafii, R.1
Juarez, M.M.2
Albertson, T.E.3
Chan, A.L.4
-
12
-
-
0024414604
-
Tumor necrosis factor/cachectin plays a key role in bleomycin-induced pneumopathy and fibrosis
-
Piguet PF, Collart MA, Grau GE, et al. Tumor necrosis factor/cachectin plays a key role in bleomycin-induced pneumopathy and fibrosis. J Exp Med 1989;170:655-63 (Pubitemid 19226654
-
(1989)
Journal of Experimental Medicine
, vol.170
, Issue.3
, pp. 655-663
-
-
Piguet, P.F.1
Collart, M.A.2
Grau, G.E.3
Kapanci, Y.4
Vassalli, P.5
-
13
-
-
55549147184
-
Treatment of idiopathic pulmonary fibrosis with etanercept: An exploratory, placebo-controlled trial
-
Raghu G, Brown KK, Costabel U, et al. Treatment of idiopathic pulmonary fibrosis with etanercept: An exploratory, placebo-controlled trial. Am J Respir Crit Care Med 2008;178:948-55
-
(2008)
Am J Respir Crit Care Med
, vol.178
, pp. 948-955
-
-
Raghu, G.1
Brown, K.K.2
Costabel, U.3
-
14
-
-
73949159217
-
Potential role of endothelin-1 in pulmonary fibrosis: From the bench to the clinic
-
Ross B, D'Orleans-Juste P, Giaid A. Potential role of endothelin-1 in pulmonary fibrosis: From the bench to the clinic. Am J Respir Cell Mol Biol 2010;42:16-20
-
(2010)
Am J Respir Cell Mol Biol
, vol.42
, pp. 16-20
-
-
Ross, B.1
D'Orleans-Juste, P.2
Giaid, A.3
-
15
-
-
0031065214
-
Elevated expression of endothelin-1 and endothelin-converting enzyme-1 in idiopathic pulmonary fibrosis: Possible involvement of proinflammatory cytokines
-
Saleh D, Furukawa K, Tsao MS, et al. Elevated expression of endothelin-1 and endothelin-converting enzyme-1 in idiopathic pulmonary fibrosis: Possible involvement of proinflammatory cytokines. Am J Respir Cell Mol Biol 1997;16:187-93 (Pubitemid 127498240
-
(1997)
American Journal of Respiratory Cell and Molecular Biology
, vol.16
, Issue.2
, pp. 187-193
-
-
Saleh, D.1
Furukawa, K.2
Tsao, M.-S.3
Maghazachi, A.4
Corrin, B.5
Yanagisawa, M.6
Barnes, P.J.7
Giaid, A.8
-
16
-
-
0027213101
-
Expression of endothelin-1 in lungs of patients with cryptogenic fibrosing alveolitis
-
DOI 10.1016/0140-6736(93)90694-C
-
Giaid A, Michel RP, Stewart DJ, et al. Expression of endothelin-1 in lungs of patients with cryptogenic fibrosingalveolitis. Lancet 1993;341:1550-4 (Pubitemid 23170459
-
(1993)
Lancet
, vol.341
, Issue.8860
, pp. 1550-1554
-
-
Giaid, A.1
Michel, R.P.2
Steward, D.J.3
Sheppard, M.4
Corrin, B.5
Hamid, Q.6
-
17
-
-
74449089564
-
Improvement of bleomycin-induced pulmonary hypertension and pulmonary fibrosis by the endothelin receptor antagonist Bosentan
-
Schroll S, Arzt M, Sebah D, et al. Improvement of bleomycin-induced pulmonary hypertension and pulmonary fibrosis by the endothelin receptor antagonist Bosentan. Respir Physiol Neurobiol 2010;170:32-6
-
(2010)
Respir Physiol Neurobiol
, vol.170
, pp. 32-36
-
-
Schroll, S.1
Arzt, M.2
Sebah, D.3
-
18
-
-
0032056141
-
Effect of endothelin receptor antagonists (BQ-485, Ro 47-0203) on collagen deposition during the development of bleomycin-induced pulmonary fibrosis in rats
-
DOI 10.1006/pupt.1998.0142
-
Mutsaers SE, Marshall RP, Goldsack NR, et al. Effect of endothelin receptor antagonists (BQ-485, Ro 47- 0203) on collagen deposition during the development of bleomycin-induced pulmonary fibrosis in rats. Pulm Pharmacol Ther 1998;11:221-5 (Pubitemid 29041586
-
(1998)
Pulmonary Pharmacology and Therapeutics
, vol.11
, Issue.2-3
, pp. 221-225
-
-
Mutsaers, S.E.1
Marshall, R.P.2
Goldsack, N.R.3
Laurent, G.J.4
McAnulty, R.J.5
-
19
-
-
37849012578
-
BUILD-1: A randomized placebocontrolled trial of bosentan in idiopathic pulmonary fibrosis
-
King TE Jr, Behr J, Brown KK, et al. BUILD-1: A randomized placebocontrolled trial of bosentan in idiopathic pulmonary fibrosis. Am J Respir Crit Care Med 2008;177:75-81
-
(2008)
Am J Respir Crit Care Med
, vol.177
, pp. 75-81
-
-
King Jr., T.E.1
Behr, J.2
Brown, K.K.3
-
20
-
-
84877297353
-
Treatment of idiopathic pulmonary fibrosis with ambrisentan: A parallel, randomized trial
-
Raghu G, Behr J, Brown KK, et al. Treatment of idiopathic pulmonary fibrosis with ambrisentan: A parallel, randomized trial. Ann Intern Med 2013;158:641-9
-
(2013)
Ann Intern Med
, vol.158
, pp. 641-649
-
-
Raghu, G.1
Behr, J.2
Brown, K.K.3
-
21
-
-
0029124143
-
Molecular mechanisms of antifibrotic effect of interferon gamma in bleomycin-mouse model of lung fibrosis: Downregulation of TGF-beta and procollagen I and III gene expression
-
Gurujeyalakshmi G, Giri SN. Molecular mechanisms of antifibrotic effect of interferon gamma in bleomycin-mouse model of lung fibrosis: Downregulation of TGF-beta and procollagen I and III gene expression. Exp Lung Res 1995;21:791-08
-
(1995)
Exp Lung Res
, vol.21
, pp. 791-718
-
-
Gurujeyalakshmi, G.1
Giri, S.N.2
-
22
-
-
67650349068
-
Effect of interferon gamma-1b on survival in patients with idiopathic pulmonary fibrosis (INSPIRE): A multicentre, randomised, placebocontrolled trial
-
King TE Jr, Albera C, Bradford WZ, et al. Effect of interferon gamma-1b on survival in patients with idiopathic pulmonary fibrosis (INSPIRE): A multicentre, randomised, placebocontrolled trial. Lancet 2009;374:222-8
-
(2009)
Lancet
, vol.374
, pp. 222-228
-
-
King Jr., T.E.1
Albera, C.2
Bradford, W.Z.3
-
23
-
-
84859418092
-
Delivery and safety of inhaled interferongamma in idiopathic pulmonary fibrosis
-
Diaz KT, Skaria S, Harris K, et al. Delivery and safety of inhaled interferongamma in idiopathic pulmonary fibrosis. J Aerosol Med Pulm Drug Deliv 2012;25:79-87
-
(2012)
J Aerosol Med Pulm Drug Deliv
, vol.25
, pp. 79-87
-
-
Diaz, K.T.1
Skaria, S.2
Harris, K.3
-
24
-
-
79959886642
-
Everolimus in IPF Study Investigators an investigator-driven study of everolimus in surgical lung biopsy confirmed idiopathic pulmonary fibrosis
-
Malouf MA, Hopkins P, Snell G, Glanville AR; Everolimus in IPF Study Investigators. An investigator-driven study of everolimus in surgical lung biopsy confirmed idiopathic pulmonary fibrosis. Respirology 2011;16:776-83
-
(2011)
Respirology
, vol.16
, pp. 776-783
-
-
Malouf, M.A.1
Hopkins, P.2
Snell, G.3
Glanville, A.R.4
-
25
-
-
0026634329
-
The protective effect of colchicine on bleomycininduced pulmonary fibrosis in rats
-
Zhang L, Zhu Y, Luo W. The protective effect of colchicine on bleomycininduced pulmonary fibrosis in rats. Chin Med Sci J 1992;7:58-60
-
(1992)
Chin Med Sci J
, vol.7
, pp. 58-60
-
-
Zhang, L.1
Zhu, Y.2
Luo, W.3
-
26
-
-
0027459992
-
Colchicine in the treatment of pulmonary fibrosis
-
Peters SG, McDougall JC, Douglas WW, et al. Colchicine in the treatment of pulmonary fibrosis. Chest 1993;103:101-4 (Pubitemid 23027240
-
(1993)
Chest
, vol.103
, Issue.1
, pp. 101-104
-
-
Peters, S.G.1
McDougall, J.C.2
Douglas, W.W.3
Coles, D.T.4
DeRemee, R.A.5
-
27
-
-
17944391083
-
Colchicine versus prednisone in the treatment of idiopathic pulmonary fibrosis: A randomized prospective study
-
Douglas WW, Ryu JH, Swensen SJ, et al. Colchicine versus prednisone in the treatment of idiopathic pulmonary fibrosis: A randomized prospective study. Members of the Lung Study Group. Am J Respir Crit Care Med 1998;158:220-5 (Pubitemid 28337184
-
(1998)
American Journal of Respiratory and Critical Care Medicine
, vol.158
, Issue.1
, pp. 220-225
-
-
Douglas, W.W.1
Ryu, J.H.2
Swensen, S.J.3
Offord, K.P.4
Schroeder, D.R.5
Caron, G.M.6
Deremee, R.A.7
Fisk, D.M.8
Krowka, M.J.9
Patel, A.M.10
Schwartz, O.A.11
-
28
-
-
0020665951
-
Collagen accumulation in irradiated rat lung: Modification by D-penicillamine
-
Ward WF, Shih-Heollwarth A, Tuttle RD. Collagen accumulation in irradiated rat lung: Modification by D-penicillamine. Radiology 1983;146:533-7 (Pubitemid 13225505
-
(1983)
Radiology
, vol.146
, Issue.2
, pp. 533-537
-
-
Ward, W.F.1
Shih Hoellwarth, A.2
Tuttle, R.D.3
-
30
-
-
0344742226
-
Prevention of bleomycin-induced lung fibrosis by aerosolization of heparin or urokinase in rabbits
-
DOI 10.1164/rccm.2201082
-
Gu?nther A, Lu?bke N, Ermert M, et al. Prevention of bleomycin-induced lung fibrosis by aerosolization of heparin or urokinase in rabbits. Am J Respir Crit Care Med 2003;168:1358-65 (Pubitemid 37487332
-
(2003)
American Journal of Respiratory and Critical Care Medicine
, vol.168
, Issue.11
, pp. 1358-1365
-
-
Gunther, A.1
Lubke, N.2
Ermert, M.3
Schermuly, R.T.4
Weissmann, N.5
Breithecker, A.6
Markart, P.7
Ruppert, C.8
Quanz, K.9
Ermert, L.10
Grimminger, F.11
Seeger, W.12
-
31
-
-
24944467299
-
Anticoagulant therapy for idiopathic pulmonary fibrosis
-
DOI 10.1378/chest.128.3.1475
-
Kubo H, Nakayama K, Yanai M, et al. Anticoagulant therapy for idiopathic pulmonary fibrosis. Chest 2005;128:1475-82 (Pubitemid 41324435
-
(2005)
Chest
, vol.128
, Issue.3
, pp. 1475-1482
-
-
Kubo, H.1
Nakayama, K.2
Yanai, M.3
Suzuki, T.4
Yamaya, M.5
Watanabe, M.6
Sasaki, H.7
-
32
-
-
77953933778
-
Safety and tolerability of inhaled heparin in idiopathic pulmonary fibrosis
-
Markart P, Nass R, Ruppert C, et al. Safety and tolerability of inhaled heparin in idiopathic pulmonary fibrosis. J Aerosol Med Pulm Drug Deliv 2010;23:161-72
-
(2010)
J Aerosol Med Pulm Drug Deliv
, vol.23
, pp. 161-172
-
-
Markart, P.1
Nass, R.2
Ruppert, C.3
-
33
-
-
0026389762
-
Azathioprine combined with prednisone in the treatment of idiopathic pulmonary fibrosis: A prospective, double-blind randomized, placebo-controlled clinical trial
-
Raghu G, Depaso WJ, Cain K, et al. Azathioprine combined with prednisone in the treatment of idiopathic pulmonary fibrosis: A prospective, double-blind randomized, placebo-controlled clinical trial. Am Rev Respir Dis 1991;144:291-6
-
(1991)
Am Rev Respir Dis
, vol.144
, pp. 291-296
-
-
Raghu, G.1
Depaso, W.J.2
Cain, K.3
-
34
-
-
0034047115
-
Cyclophosphamide in the treatment of idiopathic pulmonary fibrosis: A prospective study in patients who failed to respond to corticosteroids
-
Zisman DA, Lynch JPIII, Toews GB, et al. Cyclophosphamide in the treatment of idiopathic pulmonary fibrosis: A prospective study in patients who failed to respond to corticosteroids. Chest 2000;117:1619-26 (Pubitemid 30413354
-
(2000)
Chest
, vol.117
, Issue.6
, pp. 1619-1626
-
-
Zisman, D.A.1
Lynch III, J.P.2
Toews, G.B.3
Kazerooni, E.A.4
Flint, A.5
Martinez, F.J.6
-
35
-
-
63349085077
-
C-Jun N-terminal kinase 1 is required for the development of pulmonary fibrosis
-
Alcorn JF, van der Velden J, Brown AL, et al. c-Jun N-terminal kinase 1 is required for the development of pulmonary fibrosis. Am J Respir Cell Mol Biol 2009;40:422-32
-
(2009)
Am J Respir Cell Mol Biol
, vol.40
, pp. 422-432
-
-
Alcorn, J.F.1
Van Der Velden, J.2
Brown, A.L.3
-
36
-
-
0035149573
-
2-terminal kinase-dependent pathway
-
Hashimoto S, Gon Y, Takeshita I, et al. Transforming growth factor-beta1 induces phenotypic modulation of human lung fibroblasts to myofibroblast through a c-Jun-NH2-terminal kinasedependent pathway. Am J Respir Crit Care Med 2001;163:152-7 (Pubitemid 32095266
-
(2001)
American Journal of Respiratory and Critical Care Medicine
, vol.163
, Issue.1
, pp. 152-157
-
-
Hashimoto, S.1
Gon, Y.2
Takeshita, I.3
Matsumoto, K.4
Maruoka, S.5
Horie, T.6
-
37
-
-
84862776641
-
Discovery of CC-930, an orally active anti-fibrotic JNK inhibitor
-
PlantevinKrenitsky V, Nadolny L, Delgado M, et al. Discovery of CC-930, an orally active anti-fibrotic JNK inhibitor. Bioorg Med Chem Lett 2012;22:1433-8
-
(2012)
Bioorg Med Chem Lett
, vol.22
, pp. 1433-1438
-
-
PlantevinKrenitsky, V.1
Nadolny, L.2
Delgado, M.3
-
38
-
-
77956640423
-
A controlled trial of sildenafil in advanced idiopathic pulmonary fibrosis
-
Idiopathic Pulmonary Fibrosis Clinical Research Network
-
Idiopathic Pulmonary Fibrosis Clinical Research Network. Zisman DA, Schwarz M, Anstrom KJ, et al. A controlled trial of sildenafil in advanced idiopathic pulmonary fibrosis. N Engl J Med 2010;363:620-8
-
(2010)
N Engl J Med
, vol.363
, pp. 620-628
-
-
Zisman, D.A.1
Schwarz, M.2
Anstrom, K.J.3
-
39
-
-
0030005712
-
Constitutive activation of 5-lipoxygenase in the lungs of patients with idiopathic pulmonary fibrosis
-
Wilborn J, Bailie M, Coffey M, et al. Constitutive activation of 5-lipoxygenase in the lungs of patients with idiopathic pulmonary fibrosis. J Clin Invest 1996;97:1827-36
-
(1996)
J Clin Invest
, vol.97
, pp. 1827-1836
-
-
Wilborn, J.1
Bailie, M.2
Coffey, M.3
-
40
-
-
0037080719
-
Protection from pulmonary fibrosis in leukotriene-deficient mice
-
Peters-Golden M, Bailie M, Marshall T, et al. Protection from pulmonary fibrosis in leukotriene-deficient mice. Am J Respir Crit Care Med 2002;165:229-35 (Pubitemid 34084463
-
(2002)
American Journal of Respiratory and Critical Care Medicine
, vol.165
, Issue.2
, pp. 229-235
-
-
Peters-Golden, M.1
Bailie, M.2
Marshall, T.3
Wilke, C.4
Phan, S.H.5
Toews, G.B.6
Moore, B.B.7
-
41
-
-
33845484030
-
Pharmacological inhibition of leukotrienes in an animal model of bleomycin-induced acute lung injury
-
Failla M, Genovese T, Mazzon E, et al. Pharmacological inhibition of leukotrienes in an animal model of bleomycin-induced acute lung injury. Respir Res 2006;7:137
-
(2006)
Respir Res
, vol.7
, pp. 137
-
-
Failla, M.1
Genovese, T.2
Mazzon, E.3
-
42
-
-
0442291674
-
The role of connective tissue growth factor, a multifunctional matricellular protein, in fibroblast biology
-
DOI 10.1139/o03-069
-
Leask A, Abraham DJ. The role of connective tissue growth factor, a multifunctional matricellular protein, in fibroblast biology. Biochem Cell Biol 2003;81:355-63 (Pubitemid 38186975
-
(2003)
Biochemistry and Cell Biology
, vol.81
, Issue.6
, pp. 355-363
-
-
Leask, A.1
Abraham, D.J.2
-
43
-
-
7744234278
-
Connective tissue growth factor is crucial to inducing a profibrotic environment in fibrosis-resistant BALB/c mouse lungs
-
Bonniaud P, Martin G, Margetts PJ, et al. Connective tissue growth factor is crucial to inducing a profibrotic environment in "fibrosis- resistant" BALB/c mouse lungs. Am J Respir Cell Mol Biol 2004;31:510-16
-
(2004)
Am J Respir Cell Mol Biol
, vol.31
, pp. 510-516
-
-
Bonniaud, P.1
Martin, G.2
Margetts, P.J.3
-
44
-
-
0033258181
-
Enhanced insulin-like growth factor binding protein-related protein 2 (connective tissue growth factor) expression in patients with idiopathic pulmonary fibrosis and pulmonary sarcoidosis
-
Allen JT, Knight RA, Bloor CA, Spiteri MA. Enhanced insulin-like growth factor binding protein-related protein 2 (Connective tissue growth factor) expression in patients with idiopathic pulmonary fibrosis and pulmonary sarcoidosis. Am J Respir Cell Mol Biol 1999;6:693-700 (Pubitemid 129502288
-
(1999)
American Journal of Respiratory Cell and Molecular Biology
, vol.21
, Issue.6
, pp. 693-700
-
-
Allen, J.T.1
Knight, R.A.2
Bloor, C.A.3
Spiteri, M.A.4
-
45
-
-
79951713169
-
Cooperative interaction of ctgf and tgf-b in animal models of fibrotic disease
-
Wang Q, Usinger W, Nichols B, et al. Cooperative interaction of CTGF and TGF-b in animal models of fibrotic disease. Fibrogenesis Tissue Repair 2011;4(1):4
-
(2011)
Fibrogenesis Tissue Repair
, vol.4
, Issue.1
, pp. 4
-
-
Wang, Q.1
Usinger, W.2
Nichols, B.3
-
46
-
-
0022230283
-
Thalidomide and congeners as anti-inflammatory agents
-
Koch HP. Thalidomide and congeners as anti-inflammatory agents. Prog Med Chem 1985;22:165-42
-
(1985)
Prog Med Chem
, vol.22
, pp. 165-152
-
-
Koch, H.P.1
-
47
-
-
0027230553
-
Thalidomide exerts its inhibitory action on tumor necrosis factor α by enhancing mRNA degradation
-
Moreira AL, Sampaio EP, Zmuidzinas A, et al. Thalidomide exerts its inhibitory action on tumor necrosis factor alpha by enhancing mRNA degradation. J Exp Med 1993;177:1675-80 (Pubitemid 23146134
-
(1993)
Journal of Experimental Medicine
, vol.177
, Issue.6
, pp. 1675-1680
-
-
Moreira, A.L.1
Sampaio, E.P.2
Zmuidzinas, A.3
Frindt, P.4
Smith, K.A.5
Kaplan, G.6
-
48
-
-
0028216334
-
Thalidomide is an inhibitor of angiogenesis
-
D'Amato RJ, Loughnan MS, Flynn E, et al. Thalidomide is an inhibitor of angiogenesis. Proc Natl Acad Sci USA 1994;91:4082-5 (Pubitemid 24139577
-
(1994)
Proceedings of the National Academy of Sciences of the United States of America
, vol.91
, Issue.9
, pp. 4082-4085
-
-
D'Amato, R.J.1
Loughnan, M.S.2
Flynn, E.3
Folkman, J.4
-
49
-
-
34250872717
-
Thalidomide prevents bleomycin-induced pulmonary fibrosis in mice
-
Tabata C, Tabata R, Kadokawa Y, et al. Thalidomide prevents bleomycin-induced pulmonary fibrosis in mice. J Immunol 2007;179:708-14 (Pubitemid 46986590
-
(2007)
Journal of Immunology
, vol.179
, Issue.1
, pp. 708-714
-
-
Tabata, C.1
Tabata, R.2
Kadokawa, Y.3
Hisamori, S.4
Takahashi, M.5
Mishima, M.6
Nakano, T.7
Kubo, H.8
-
50
-
-
84868327008
-
Thalidomide for the treatment of cough in idiopathic pulmonary fibrosis: A randomized trial
-
Horton MR, Santopietro V, Mathew L, et al. Thalidomide for the treatment of cough in idiopathic pulmonary fibrosis: A randomized trial. Ann Intern Med 2012;157:398-06
-
(2012)
Ann Intern Med
, vol.157
, pp. 398-316
-
-
Horton, M.R.1
Santopietro, V.2
Mathew, L.3
-
51
-
-
0034104598
-
Interleukin-13 modulates collagen homeostasis in human skin and keloid fibroblasts
-
Oriente A, Fedarko NS, Pacocha SE, et al. Interleukin-13 modulates collagen homeostasis in human skin and keloid fibroblasts. J Pharmacol Exp Ther 2000;292:988-94 (Pubitemid 30136592
-
(2000)
Journal of Pharmacology and Experimental Therapeutics
, vol.292
, Issue.3
, pp. 988-994
-
-
Oriente, A.1
Fedarko, N.S.2
Pacocha, S.E.3
Huang, S.-K.4
Lichtenstein, L.M.5
Essayan, D.M.6
-
52
-
-
0242405834
-
Potential action of IL-4 and IL-13 as fibrogenic factors on lung fibroblasts in vitro
-
DOI 10.1159/000073718
-
Saito A, Okazaki H, Sugawara I, et al. Potential action of IL-4 and IL-13 as fibrogenic factors on lung fibroblasts in vitro. Int Arch Allergy Immunol 2003;132:168-76 (Pubitemid 37409848
-
(2003)
International Archives of Allergy and Immunology
, vol.132
, Issue.2
, pp. 168-176
-
-
Saito, A.1
Okazaki, H.2
Sugawara, I.3
Yamamoto, K.4
Takizawa, H.5
-
53
-
-
40949099967
-
Interleukin-13 acts as an apoptotic effector on lung epithelial cells and induces pro-fibrotic gene expression in lung fibroblasts
-
DOI 10.1111/j.1365-2222.2008.02944.x
-
Borowski A, Kuepper M, Horn U, et al. Interleukin-13 acts as an apoptotic effector on lung epithelial cells and induces pro-fibrotic gene expression in lung fibroblasts. Clin Exp Allergy 2008;38:619-28 (Pubitemid 351406073
-
(2008)
Clinical and Experimental Allergy
, vol.38
, Issue.4
, pp. 619-628
-
-
Borowski, A.1
Kuepper, M.2
Horn, U.3
Knupfer, U.4
Zissel, G.5
Hohne, K.6
Luttmann, W.7
Krause, S.8
Virchow Jr., J.C.9
Friedrich, K.10
-
54
-
-
0031606459
-
Production of interleukin 13 by alveolar macrophages from normal and fibrotic lung
-
Hancock A, Armstrong L, Gama R, Millar A. Production of interleukin 13 by alveolar macrophages from normal and fibrotic lung. Am J Respir Cell Mol Biol 1998;18:60-5 (Pubitemid 128355347
-
(1998)
American Journal of Respiratory Cell and Molecular Biology
, vol.18
, Issue.1
, pp. 60-65
-
-
Hancock, A.1
Armstrong, L.2
Gama, R.3
Millar, A.4
-
55
-
-
0033560126
-
Pulmonary expression of interleukin-13 causes inflammation, mucus hypersecretion, subepithelial fibrosis, physiologic abnormalities, and eotaxin production
-
Zhu Z, Homer RJ, Wang Z, et al. Pulmonary expression of interleukin-13 causes inflammation, mucus hypersecretion, subepithelial fibrosis, physiologic abnormalities, and eotaxin production. J Clin Invest 1999;103:779-88 (Pubitemid 29152623
-
(1999)
Journal of Clinical Investigation
, vol.103
, Issue.6
, pp. 779-788
-
-
Zhu, Z.1
Homer, R.J.2
Wang, Z.3
Chen, Q.4
Geba, G.P.5
Wang, J.6
Zhang, Y.7
Elias, J.A.8
-
56
-
-
1642333177
-
Protection from Fluorescein Isothiocyanate-Induced Fibrosis in IL-13-Deficient, but Not IL-4-Deficient, Mice Results from Impaired Collagen Synthesis by Fibroblasts
-
Kolodsick JE, Toews GB, Jakubzick C, et al. Protection from fluorescein isothiocyanate-induced fibrosis in IL-13- deficient, but not IL-4-deficient, mice results from impaired collagen synthesis by fibroblasts. J Immunol 2004;172:4068-76 (Pubitemid 38375218
-
(2004)
Journal of Immunology
, vol.172
, Issue.7
, pp. 4068-4076
-
-
Kolodsick, J.E.1
Toews, G.B.2
Jakubzick, C.3
Hogaboam, C.4
Moore, T.A.5
McKenzie, A.6
Wilke, C.A.7
Chrisman, C.J.8
Moore, B.B.9
-
57
-
-
0036787916
-
Interaction of IL-13 and C10 in the pathogenesis of bleomycin-induced pulmonary fibrosis
-
Belperio JA, Dy M, Burdick MD, et al. Interaction of IL-13 and C10 in the pathogenesis of bleomycin-induced pulmonary fibrosis. Am JRespir Cell Mol Biol 2002;27:419-27
-
(2002)
Am JRespir Cell Mol Biol
, vol.27
, pp. 419-427
-
-
Belperio, J.A.1
Dy, M.2
Burdick, M.D.3
-
58
-
-
33749048089
-
111In-octreotide in idiopathic pulmonary fibrosis
-
Lebtahi R, Moreau S, Marchand-Adam S, et al. Increased uptake of 111In-octreotide in idiopathic pulmonary fibrosis. J Nucl Med 2006;47:1281-7 (Pubitemid 47544880
-
(2006)
Journal of Nuclear Medicine
, vol.47
, Issue.8
, pp. 1281-1287
-
-
Lebtahi, R.1
Moreau, S.2
Marchand-Adam, S.3
Debray, M.-P.4
Brauner, M.5
Soler, P.6
Marchal, J.7
Raguin, O.8
Gruaz-Guyon, A.9
Reubi, J.-C.10
Le Guludec, D.11
Crestani, B.12
-
59
-
-
29244448718
-
Somatostatin at nanomolar concentration reduces collagen I and III synthesis by, but not proliferation of activated rat hepatic stellate cells
-
DOI 10.1038/sj.bjp.0706298
-
Reynaert H, Rombouts K, Jia Y, et al. Somatostatin at nanomolar concentration reduces collagen I and III synthesis by, but not proliferation of activated rat hepatic stellate cells. Br J Pharmacol 2005;146:77-88 (Pubitemid 43086097
-
(2005)
British Journal of Pharmacology
, vol.146
, Issue.1
, pp. 77-88
-
-
Reynaert, H.1
Rombouts, K.2
Jia, Y.3
Urbain, D.4
Chatterjee, N.5
Uyama, N.6
Geerts, A.7
-
60
-
-
0035078667
-
Influence of short-term octreotide administration on chronic tissue injury, transforming growth factor β (TGF-β) overexpression, and collagen accumulation in irradiated rat intestine
-
Wang J, Zheng H, Hauer-Jensen M. Influence of Short-Term Octreotide Administration on Chronic Tissue Injury, Transforming Growth Factor beta (TGF-beta) Overexpression, and Collagen Accumulation in Irradiated Rat Intestine. J Pharmacol Exp Ther 2001;297:35-42 (Pubitemid 32242560
-
(2001)
Journal of Pharmacology and Experimental Therapeutics
, vol.297
, Issue.1
, pp. 35-42
-
-
Wang, J.1
Zheng, H.2
Hauer-Jensen, M.3
-
61
-
-
1542299761
-
Octreotide regulates CC but not CXC LPS-induced chemokine secretion in rat Kupffer cells
-
DOI 10.1038/sj.bjp.0705633
-
Valatas V, Kolios G, Manousou P, et al. Octreotide regulates CC but not CXC LPS-induced chemokine secretion in rat Kupffer cells. Br J Pharmacol 2004;141:477-87 (Pubitemid 38297010
-
(2004)
British Journal of Pharmacology
, vol.141
, Issue.3
, pp. 477-487
-
-
Valatas, V.1
Kolios, G.2
Manousou, P.3
Notas, G.4
Xidakis, C.5
Diamantis, I.6
Kouroumalis, E.7
-
62
-
-
40649115985
-
Activation of somatostatin receptors attenuates pulmonary fibrosis
-
DOI 10.1136/thx.2007.078006
-
Borie R, Fabre A, Prost F, et al. Activation of somatostatin receptors attenuates pulmonary fibrosis. Thorax 2008;63:251-8 (Pubitemid 351373721
-
(2008)
Thorax
, vol.63
, Issue.3
, pp. 251-258
-
-
Borie, R.1
Fabre, A.2
Prost, F.3
Marchal-Somme, J.4
Lebtahi, R.5
Marchand-Adam, S.6
Aubier, M.7
Soler, P.8
Crestani, B.9
-
63
-
-
84860320360
-
Octreotide treatment of idiopathic pulmonary fibrosis: A proof-of-concept study
-
Crestani B, Chapron J, Wallaert B, et al. Octreotide treatment of idiopathic pulmonary fibrosis: A proof-of-concept study. Eur Respir J 2012;39:772-5
-
(2012)
Eur Respir J
, vol.39
, pp. 772-775
-
-
Crestani, B.1
Chapron, J.2
Wallaert, B.3
-
64
-
-
38049091636
-
The Lysophosphatidic acid receptor LPA1 links pulmonary fibrosis to lung injury by mediating fibroblast recruitment and vascular leak
-
Tager AM, LaCamera P, Shea BS, et al. The Lysophosphatidic acid receptor LPA1 links pulmonary fibrosis to lung injury by mediating fibroblast recruitment and vascular leak. Nat Med 2008;14:45-54
-
(2008)
Nat Med
, vol.14
, pp. 45-54
-
-
Tager, A.M.1
LaCamera, P.2
Shea, B.S.3
-
65
-
-
38049058468
-
From lung injury to fibrosis
-
Ley K, Zarbock A. From lung injury to fibrosis. Nat Med 2008;14:20-2
-
(2008)
Nat Med
, vol.14
, pp. 20-22
-
-
Ley, K.1
Zarbock, A.2
-
66
-
-
0037371153
-
Lysyl oxidase: Properties, specificity, and biological roles inside and outside of the cell
-
DOI 10.1002/jcb.10413
-
Kagan HM, Li W. Lysyl oxidase: Properties, specificity, and biological roles inside and outside of the cell. J Cell Biochem 2003;88:660-72 (Pubitemid 36258816
-
(2003)
Journal of Cellular Biochemistry
, vol.88
, Issue.4
, pp. 660-672
-
-
Kagan, H.M.1
Li, W.2
-
67
-
-
0028675380
-
Regulation of lysyl oxidase expression in lung fibroblasts by transforming growth factor-b1 and prostaglandin E2
-
Boak AM, Roy R, Berk J, et al. Regulation of lysyl oxidase expression in lung fibroblasts by transforming growth factor-b1 and prostaglandin E2. Am J Respir Cell Mol Biol 1994;11:751-5
-
(1994)
Am J Respir Cell Mol Biol
, vol.11
, pp. 751-755
-
-
Boak, A.M.1
Roy, R.2
Berk, J.3
-
68
-
-
77956425361
-
Allosteric inhibition of lysyl oxidase-like-2 impedes the development of a pathologic microenvironment
-
Barry-Hamilton V, Spangler R, Marshall D, et al. Allosteric inhibition of lysyl oxidase-like-2 impedes the development of a pathologic microenvironment. Nat Med 2010;16:1009-17
-
(2010)
Nat Med
, vol.16
, pp. 1009-1017
-
-
Barry-Hamilton, V.1
Spangler, R.2
Marshall, D.3
-
69
-
-
77953261195
-
Pirfenidone: Antifibrotic agent for idiopathic pulmonary fibrosis
-
Azuma A. Pirfenidone: Antifibrotic agent for idiopathic pulmonary fibrosis. Expert Rev Resp Med 2010;4:301-10
-
(2010)
Expert Rev Resp Med
, vol.4
, pp. 301-310
-
-
Azuma, A.1
-
70
-
-
20944434994
-
Double-blind, placebo-controlled trial of pirfenidone in patients with idiopathic pulmonary fibrosis
-
DOI 10.1164/rccm.200404-571OC
-
Azuma A, Nukiwa T, Tsuboi E, et al. Double-blind, placebo-controlled trial of pirfenidone in patients with idiopathic pulmonary fibrosis. Am J Respir Crit Care Med 2005;171:1040-7 (Pubitemid 40616955
-
(2005)
American Journal of Respiratory and Critical Care Medicine
, vol.171
, Issue.9
, pp. 1040-1047
-
-
Azuma, A.1
Nukiwa, T.2
Tsuboi, E.3
Suga, M.4
Abe, S.5
Nakata, K.6
Taguchi, Y.7
Nagai, S.8
Itoh, H.9
Ohi, M.10
Sato, A.11
Kudoh, S.12
Raghu, G.13
-
71
-
-
77951160564
-
Pirfenidone clinical study group in japan pirfenidone in idiopathic pulmonary fibrosis: A phase iii clinical trial in japan
-
Taniguchi H, Ebina M, Kondoh Y, et al. Pirfenidone clinical study group in Japan. Pirfenidone in idiopathic pulmonary fibrosis: A phase III clinical trial in Japan. Eur Respir J 2010;35:821-9
-
(2010)
Eur Respir J
, vol.35
, pp. 821-829
-
-
Taniguchi, H.1
Ebina, M.2
Kondoh, Y.3
-
72
-
-
81255146512
-
Exploratory analysis of a Phase III trial of pirfenidone identifies a subpopulation of patients with idiopathic pulmonary fibrosis as benefiting from treatment
-
Pirfenidone Clinical Study Group in Japan
-
Azuma A, Taguchi Y, Ogura T, Pirfenidone Clinical Study Group in Japan. Exploratory analysis of a Phase III trial of pirfenidone identifies a subpopulation of patients with idiopathic pulmonary fibrosis as benefiting from treatment. Respir Res 2011;12:143
-
(2011)
Respir Res
, vol.12
, pp. 143
-
-
Azuma, A.1
Taguchi, Y.2
Ogura, T.3
-
73
-
-
34548072307
-
N-Acetylcysteine-A safe antidote for cysteine/glutathione deficiency
-
DOI 10.1016/j.coph.2007.04.005, PII S1471489207000896, Cancer/Immunomodulation
-
Atkuri KR, Mantovani JJ, Herzenberg LA. N-Acetylcysteine-A safe antidote for cysteine/glutathione deficiency. Curr Opin Pharmacol 2007;7:355-9 (Pubitemid 47289259
-
(2007)
Current Opinion in Pharmacology
, vol.7
, Issue.4
, pp. 355-359
-
-
Atkuri, K.R.1
Mantovani, J.J.2
Herzenberg, L.A.3
Herzenberg, L.A.4
-
74
-
-
0031449645
-
Antioxidative and clinical effects of highdose n-Acetylcysteine in fibrosingalveolitis: Adjunctive therapy to maintenance immunosuppression
-
Behr J, Maier K, Degenkolb B, et al. Antioxidative and clinical effects of highdose n-Acetylcysteine in fibrosingalveolitis: Adjunctive therapy to maintenance immunosuppression. Am J Respir Crit Care Med 1997;156:1897-01
-
(1997)
Am J Respir Crit Care Med
, vol.156
, pp. 1897-1811
-
-
Behr, J.1
Maier, K.2
Degenkolb, B.3
-
75
-
-
28144459814
-
High-dose acetylcysteine in idiopathic pulmonary fibrosis
-
DOI 10.1056/NEJMoa042976
-
Demedts M, Behr J, Buhl R, et al. High-dose acetylcysteine in idiopathic pulmonary fibrosis. N Engl J Med 2005;353:2229-42 (Pubitemid 41697286
-
(2005)
New England Journal of Medicine
, vol.353
, Issue.21
, pp. 2229-2242
-
-
Demedts, M.1
Behr, J.2
Buhl, R.3
Costabel, U.4
Dekhuijzen, R.5
Jansen, H.M.6
MacNee, W.7
Thomeer, M.8
Wallaert, B.9
Laurent, F.10
Nicholson, A.G.11
Verbeken, E.K.12
Verschakelen, J.13
Flower, C.D.R.14
Capron, F.15
Petruzzelli, S.16
De Vuyst, P.17
Van Den Bosch, J.M.M.18
Rodriguez-Becerra, E.19
Corvasce, G.20
Lankhorst, I.21
Sardina, M.22
Montanari, M.23
more..
-
76
-
-
0030800795
-
Adenovector-mediated gene transfer of active transforming growth factor- β1 induces prolonged severe fibrosis in rat lung
-
Sime PJ, Xing Z, Graham FL, et al. Adenovector-mediated gene transfer of active transforming growth factor-beta1 induces prolonged severe fibrosis in rat lung. J Clin Invest 1997;100:768-76 (Pubitemid 27371693
-
(1997)
Journal of Clinical Investigation
, vol.100
, Issue.4
, pp. 768-776
-
-
Sime, P.J.1
Xing, Z.2
Graham, F.L.3
Csaky, K.G.4
Gauldie, J.5
-
77
-
-
0037241857
-
Re-evaluation of fibrogenic cytokines in lung fibrosis
-
DOI 10.2174/1381612033392341
-
Kelly M, Kolb M, Bonniaud P, Gauldie J. A re-evaluation of fibrogenic cytokines in lung fibrosis. Curr Pharm Des 2003;9:39-49 (Pubitemid 36131704
-
(2003)
Current Pharmaceutical Design
, vol.9
, Issue.1
, pp. 39-49
-
-
Kelly, M.1
Kolb, M.2
Bonniaud, P.3
Gauldie, J.4
-
78
-
-
20244383986
-
Progressive transforming growth factor β1-induced lung fibrosis is blocked by an orally active ALK5 kinase inhibitor
-
DOI 10.1164/rccm.200405-612OC
-
Bonniaud P, Margetts PJ, Kolb M, et al. Progressive transforming growth factor beta1-induced lung fibrosis is blocked by an orally active ALK5 kinase inhibitor. Am J Respir Crit Care Med 2005;171:889-98 (Pubitemid 40562720
-
(2005)
American Journal of Respiratory and Critical Care Medicine
, vol.171
, Issue.8
, pp. 889-898
-
-
Bonniaud, P.1
Margetts, P.J.2
Kolb, M.3
Schroeder, J.A.4
Kapoun, A.M.5
Damm, D.6
Murphy, A.7
Chakravarty, S.8
Dugar, S.9
Higgins, L.10
Protter, A.A.11
Gauldie, J.12
-
79
-
-
34249666220
-
Inhibition of activin receptor-like kinase 5 attenuates Bleomycin-induced pulmonary fibrosis
-
DOI 10.1016/j.yexmp.2006.12.003, PII S0014480006001444
-
Higashiyama H, Yoshimoto D, Kaise T, et al. Inhibition of activin receptor-like kinase 5 attenuates bleomycin-induced pulmonary fibrosis. Exp Mol Pathol 2007;83:39-46 (Pubitemid 46842964
-
(2007)
Experimental and Molecular Pathology
, vol.83
, Issue.1
, pp. 39-46
-
-
Higashiyama, H.1
Yoshimoto, D.2
Kaise, T.3
Matsubara, S.4
Fujiwara, M.5
Kikkawa, H.6
Asano, S.7
Kinoshita, M.8
-
80
-
-
38049002642
-
Partial inhibition of integrin alpha v beta6 prevents pulmonary fibrosis without exacerbating inflammation
-
Horan GS, Wood S, Ona V, et al. Partial inhibition of integrin alpha(v) beta6 prevents pulmonary fibrosis without exacerbating inflammation. Am J Respir Crit Care Med 2008;177:56-65
-
(2008)
Am J Respir Crit Care Med
, vol.177
, pp. 56-65
-
-
Horan, G.S.1
Wood, S.2
Ona, V.3
-
81
-
-
77956036249
-
NOX4/NADPH oxidase expression is increased in pulmonary fibroblasts from patients with idiopathic pulmonary fibrosis and mediates TGFbeta1-induced fibroblast differentiation into myofibroblasts
-
Amara N, Goven D, Prost F, et al. NOX4/NADPH oxidase expression is increased in pulmonary fibroblasts from patients with idiopathic pulmonary fibrosis and mediates TGFbeta1-induced fibroblast differentiation into myofibroblasts. Thorax 2010;65:733-8
-
(2010)
Thorax
, vol.65
, pp. 733-738
-
-
Amara, N.1
Goven, D.2
Prost, F.3
-
82
-
-
78149268561
-
First in class, potent, and orally bioavailable NADPH oxidase isoform 4 (Nox4) inhibitors for the treatment of idiopathic pulmonary fibrosis
-
Laleu B, Gaggini F, Orchard M, et al. First in class, potent, and orally bioavailable NADPH oxidase isoform 4 (Nox4) inhibitors for the treatment of idiopathic pulmonary fibrosis. J Med Chem 2010;53:7715-30
-
(2010)
J Med Chem
, vol.53
, pp. 7715-7730
-
-
Laleu, B.1
Gaggini, F.2
Orchard, M.3
-
83
-
-
0242500879
-
Aberrant Wnt/beta-catenin pathway activation in idiopathic pulmonary fibrosis
-
Chilosi M, Poletti V, Zamò A, et al. Aberrant Wnt/beta-catenin pathway activation in idiopathic pulmonary fibrosis. Am J Pathol 2003;162:1495-02
-
(2003)
Am J Pathol
, vol.162
, pp. 1495-1412
-
-
Chilosi, M.1
Poletti, V.2
Zamò, A.3
-
84
-
-
0029851485
-
Keratinocyte growth factor ameliorates radiation- And bleomycin-induced lung injury and mortality
-
Yi ES, Williams ST, Lee H, et al. Keratinocyte growth factor ameliorates radiation- And bleomycin-induced lung injury and mortality. Am J Pathol 1996;149:1963-70 (Pubitemid 26415215
-
(1996)
American Journal of Pathology
, vol.149
, Issue.6
, pp. 1963-1970
-
-
Yi, E.S.1
Williams, S.T.2
Lee, H.3
Malicki, D.M.4
Chin, E.M.5
Yin, S.6
Tarpley, J.7
Ulich, T.R.8
-
85
-
-
71049119028
-
Bone marrow stem cells expressing keratinocyte growth factor via an inducible lentivirus protects against bleomycin-induced pulmonary fibrosis
-
Aguilar S, Scotton CJ, McNulty K, et al. Bone marrow stem cells expressing keratinocyte growth factor via an inducible lentivirus protects against bleomycin-induced pulmonary fibrosis. PLoS ONE 2009;4:e8013
-
(2009)
PLoS ONE
, vol.4
-
-
Aguilar, S.1
Scotton, C.J.2
McNulty, K.3
-
86
-
-
84875125485
-
Hepatocyte growth factor is an attractive target for the treatment of pulmonary fibrosis
-
Chakraborty S, Chopra P, Hak A, et al. Hepatocyte growth factor is an attractive target for the treatment of pulmonary fibrosis. Expert Opin Investig Drugs 2013;22:499-515
-
(2013)
Expert Opin Investig Drugs
, vol.22
, pp. 499-515
-
-
Chakraborty, S.1
Chopra, P.2
Hak, A.3
-
88
-
-
0033862955
-
Abrogation of bleomycin-induced epithelial apoptosis and lung fibrosis by captopril or by a caspase inhibitor
-
Wang R, Ibarra-Sunga O, Verlinski L, et al. Abrogation of bleomycin-induced epithelial apoptosis and lung fibrosis by captopril or by a caspase inhibitor. Am J Physiol Lung Cell Mol Physiol 2000;279:L143-51
-
(2000)
Am J Physiol Lung Cell Mol Physiol
, vol.279
-
-
Wang, R.1
Ibarra-Sunga, O.2
Verlinski, L.3
-
89
-
-
0032901266
-
Carbon monoxide provides protection against hyperoxic lung injury
-
Otterbein LE, Mantell LL, Choi AM. Carbon monoxide provides protection against hyperoxic lung injury. Am J Physiol 1999;276:L688-94
-
(1999)
Am J Physiol
, vol.276
-
-
Otterbein, L.E.1
Mantell, L.L.2
Choi, A.M.3
-
90
-
-
0037969711
-
Carbon monoxide induces cytoprotection in rat orthotopic lung transplantation via anti-inflammatory and anti-Apoptotic effects
-
Song R, Kubo M, Morse D, et al. Carbon monoxide induces cytoprotection in rat orthotopic lung transplantation via anti-inflammatory and anti-Apoptotic effects. Am J Pathol 2003;163:231-42 (Pubitemid 36759607
-
(2003)
American Journal of Pathology
, vol.163
, Issue.1
, pp. 231-242
-
-
Song, R.1
Kubo, M.2
Morse, D.3
Zhou, Z.4
Zhang, X.5
Dauber, J.H.6
Fabisiak, J.7
Alber, S.M.8
Watkins, S.C.9
Zuckerbraun, B.S.10
Otterbein, L.E.11
Ning, W.12
Oury, T.D.13
Lee, P.J.14
McCurry, K.R.15
Choi, A.M.K.16
-
92
-
-
0034071424
-
Carbon monoxide has anti-inflammatory effects involving the mitogen- Activated protein kinase pathway
-
DOI 10.1038/74680
-
Otterbein LE, Bach FH, Alam J, et al. Carbon monoxide has anti-inflammatory effects involving the mitogen-Activated protein kinase pathway. Nat Med 2000;6:422-8 (Pubitemid 30208159
-
(2000)
Nature Medicine
, vol.6
, Issue.4
, pp. 422-428
-
-
Otterbein, L.E.1
Bach, F.H.2
Alam, J.3
Soares, M.4
Lu, H.T.5
Wysk, M.6
Davis, R.J.7
Flavell, R.A.8
Choi, A.M.K.9
-
93
-
-
11144241299
-
Carbon monoxide suppresses bleomycin-induced lung fibrosis
-
Zhou Z, Song R, Fattman CL, et al. Carbon monoxide suppresses bleomycininduced lung fibrosis. Am J Pathol 2005;166:27-37 (Pubitemid 40051657
-
(2005)
American Journal of Pathology
, vol.166
, Issue.1
, pp. 27-37
-
-
Zhou, Z.1
Song, R.2
Fattman, C.L.3
Greenhill, S.4
Alber, S.5
Oury, T.D.6
Choi, A.M.K.7
Morse, D.8
-
94
-
-
84872304968
-
Current and novel drug therapies for idiopathicpulmonary fibrosis
-
Adamali HI, Maher TM. Current and novel drug therapies for idiopathicpulmonary fibrosis. Drug Des Devel Ther 2012;6:261-72
-
(2012)
Drug Des Devel Ther
, vol.6
, pp. 261-272
-
-
Adamali, H.I.1
Maher, T.M.2
-
95
-
-
0037114214
-
ENA-78 is an important angiogenic factor in idiopathic pulmonary fibrosis
-
Keane MP, Belperio JA, Burdick MD, et al. ENA-78 is an important angiogenic factor in idiopathic pulmonary fibrosis. Am J Respir Crit Care Med 2001;164:2239-42 (Pubitemid 34032941
-
(2001)
American Journal of Respiratory and Critical Care Medicine
, vol.164
, Issue.12
, pp. 2239-2242
-
-
Keane, M.P.1
Belperio, J.A.2
Burdick, M.D.3
Lynch III, J.P.4
Fishbein, M.C.5
Strieter, R.M.6
-
96
-
-
12744262853
-
CXCL11 attenuates bleomycininduced pulmonary fibrosis via inhibition of vascular remodeling
-
Burdick MD, Murray LA, Keane MP, et al. CXCL11 attenuates bleomycininduced pulmonary fibrosis via inhibition of vascular remodeling. Am J Respir Crit Care Med 2005;171:261-8
-
(2005)
Am J Respir Crit Care Med
, vol.171
, pp. 261-268
-
-
Burdick, M.D.1
Murray, L.A.2
Keane, M.P.3
-
97
-
-
8444244570
-
Inhibition of key cytokines by tetrathiomolybdate in the bleomycin model of pulmonary fibrosis
-
DOI 10.1016/j.jinorgbio.2004.10.006, PII S0162013404003095
-
Brewer GJ, Dick R, Ullenbruch MR, et al. Inhibition of key cytokines by tetrathiomolybdate in the bleomycin model of pulmonary fibrosis. J Inorg Biochem 2004;98:2160-7 (Pubitemid 39488145
-
(2004)
Journal of Inorganic Biochemistry
, vol.98
, Issue.12
, pp. 2160-2167
-
-
Brewer, G.J.1
Dick, R.2
Ullenbruch, M.R.3
Jin, H.4
Phan, S.H.5
-
98
-
-
77954799484
-
Vasohibin attenuates bleomycin induced pulmonary fibrosis via inhibition of angiogenesis in mice
-
Wang X, Zhu H, Yang X, et al. Vasohibin attenuates bleomycin induced pulmonary fibrosis via inhibition of angiogenesis in mice. Pathology 2010;42:457-62
-
(2010)
Pathology
, vol.42
, pp. 457-462
-
-
Wang, X.1
Zhu, H.2
Yang, X.3
-
99
-
-
84877854763
-
Endostatin, an angiogenesis inhibitor, ameliorates bleomycin-induced pulmonary fibrosis in rats
-
Wan YY, Tian GY, Guo HS, et al. Endostatin, an angiogenesis inhibitor, ameliorates bleomycin-induced pulmonary fibrosis in rats. Respir Res 2013;14:56
-
(2013)
Respir Res
, vol.14
, pp. 56
-
-
Wan, Y.Y.1
Tian, G.Y.2
Guo, H.S.3
-
100
-
-
84877043110
-
Role of matrix metaloproteases in idiopathic pulmonary fibrosis
-
Pardo A, Selman M. Role of matrix metaloproteases in idiopathic pulmonary fibrosis. Fibrogenesis Tissue Repair 2012;5:S9
-
(2012)
Fibrogenesis Tissue Repair
, vol.5
-
-
Pardo, A.1
Selman, M.2
-
101
-
-
31944448350
-
Doxycycline attenuated pulmonary fibrosis induced by bleomycin in mice
-
DOI 10.1128/AAC.50.2.739-743.2006
-
Fujita M, Ye Q, Ouchi H, et al. Doxycycline attenuated pulmonary fibrosis induced by bleomycin in mice. Antimicrob Agents Chemother 2006;50:739-43 (Pubitemid 43190990
-
(2006)
Antimicrobial Agents and Chemotherapy
, vol.50
, Issue.2
, pp. 739-743
-
-
Fujita, M.1
Ye, Q.2
Ouchi, H.3
Harada, E.4
Inoshima, I.5
Kuwano, K.6
Nakanishi, Y.7
-
102
-
-
77953463384
-
The role of long-term doxycycline in patients of idiopathic pulmonaryfibrosis: The results of an open prospective trial
-
Bhattacharyya P, Nag S, Bardhan S, et al. The role of long-term doxycycline in patients of idiopathic pulmonaryfibrosis: The results of an open prospective trial. Lung India 2009;26:81-5
-
(2009)
Lung India
, vol.26
, pp. 81-85
-
-
Bhattacharyya, P.1
Nag, S.2
Bardhan, S.3
-
103
-
-
84857881755
-
Regulation of transforming growth factor-b1-driven lung fibrosis by galectin-3
-
Mackinnon AC, Gibbons MA, Farnworth SL, et al. Regulation of transforming growth factor-b1-driven lung fibrosis by galectin-3. Am J Respir Crit Care Med 2012;185:537-46
-
(2012)
Am J Respir Crit Care Med
, vol.185
, pp. 537-546
-
-
Mackinnon, A.C.1
Gibbons, M.A.2
Farnworth, S.L.3
-
104
-
-
25444467151
-
Growth factors in idiopathic pulmonary fibrosis: Relative roles
-
Allen JT, Spiteri MA. Growth factors in idiopathic pulmonary fibrosis: Relative roles. Respir Res 2002;3:13
-
(2002)
Respir Res
, vol.3
, pp. 13
-
-
Allen, J.T.1
Spiteri, M.A.2
-
105
-
-
49649123154
-
BIBF 1120: Triple angiokinase inhibitor with sustained receptor blockade and good antitumor efficacy
-
Hilberg F, Roth GJ, Krssak M, et al. BIBF 1120: Triple angiokinase inhibitor with sustained receptor blockade and good antitumor efficacy. Cancer Res 2008;68:4774-82
-
(2008)
Cancer Res
, vol.68
, pp. 4774-4782
-
-
Hilberg, F.1
Roth, G.J.2
Krssak, M.3
-
106
-
-
80053091084
-
Efficacy of a tyrosine kinase inhibitor in idiopathic pulmonary fibrosis
-
Richeldi L, Costabel U, Selman M, et al. Efficacy of a tyrosine kinase inhibitor in idiopathic pulmonary fibrosis. N Engl J Med 2011;365:1079-87
-
(2011)
N Engl J Med
, vol.365
, pp. 1079-1087
-
-
Richeldi, L.1
Costabel, U.2
Selman, M.3
-
107
-
-
0025053989
-
Platelet-derived growth factor in idiopathic pulmonary fibrosis
-
Antoniades HN, Bravo MA, Avila RE, et al. Platelet-derived growth factor in idiopathic pulmonary fibrosis. J Clin Invest 1990;86:1055-64 (Pubitemid 20370408
-
(1990)
Journal of Clinical Investigation
, vol.86
, Issue.4
, pp. 1055-1064
-
-
Antoniades, H.N.1
Bravo, M.A.2
Avila, R.E.3
Galanopoulos, T.4
Neville-Golden, J.5
Maxwell, M.6
Selman, M.7
-
108
-
-
15244339164
-
Imatinib mesylate inhibits the profibrogenic activity of TGF-β and prevents bleomycin-mediated lung fibrosis
-
DOI 10.1172/JCI200419603
-
Daniels CE, Wilkes MC, Edens M, et al. Imatinibmesylate inhibits the profibrogenic activity of TGF-beta and prevents bleomycin-mediated lung fibrosis. J Clin Invest 2004;114:1308-16 (Pubitemid 40385302
-
(2004)
Journal of Clinical Investigation
, vol.114
, Issue.9
, pp. 1308-1316
-
-
Daniels, C.E.1
Wilkes, M.C.2
Edens, M.3
Kottom, T.J.4
Murphy, S.J.5
Limper, A.H.6
Leof, E.B.7
-
109
-
-
77749324295
-
Imatinib-IPF Study Investigators.Imatinib treatment for idiopathic pulmonary fibrosis: Randomized placebo-controlled trial results
-
Daniels CE, Lasky JA, Limper AH, et al. Imatinib-IPF Study Investigators.Imatinib treatment for idiopathic pulmonary fibrosis: Randomized placebo-controlled trial results. Am J Respir Crit Care Med 2010;181:604-10
-
(2010)
Am J Respir Crit Care Med
, vol.181
, pp. 604-610
-
-
Daniels, C.E.1
Lasky, J.A.2
Limper, A.H.3
-
110
-
-
84883175889
-
Peptide-mediated inhibition of mitogenactivated proteinkinase-Activated protein kinase-2 ameliorates bleomycin-induced pulmonary fibrosis
-
Vittal R, Fisher A, Gu H, et al. Peptide-mediated inhibition of mitogenactivated proteinkinase-Activated protein kinase-2 ameliorates bleomycin-induced pulmonary fibrosis. Am J Respir Cell Mol Biol 2013;49:47-57
-
(2013)
Am J Respir Cell Mol Biol
, vol.49
, pp. 47-57
-
-
Vittal, R.1
Fisher, A.2
Gu, H.3
-
111
-
-
84877261137
-
PI3K p110gamma overexpression in idiopathic pulmonary fibrosis lung tissue and fibroblast cells: In vitro effects of its inhibition
-
Conte E, Gili E, Fruciano M, et al. PI3K p110gamma overexpression in idiopathic pulmonary fibrosis lung tissue and fibroblast cells: In vitro effects of its inhibition. Lab Invest 2013;93:566-76
-
(2013)
Lab Invest
, vol.93
, pp. 566-576
-
-
Conte, E.1
Gili, E.2
Fruciano, M.3
-
112
-
-
77955480020
-
A phosphoinositide 3-kinase-gamma inhibitor, as605240 prevents bleomycininduced pulmonary fibrosis in rats
-
Wei X, Han J, Chen ZZ, et al. A phosphoinositide 3-kinase-gamma inhibitor, AS605240 prevents bleomycininduced pulmonary fibrosis in rats. Biochem Biophys Res Commun 2010;397:311-17
-
(2010)
Biochem Biophys Res Commun
, vol.397
, pp. 311-317
-
-
Wei, X.1
Han, J.2
Chen, Z.Z.3
-
113
-
-
79951837302
-
Phosphoinositide 3-kinase g plays a critical role in bleomycin-induced pulmonary inflammation and fibrosis in mice
-
Russo RC, Garcia CC, Barcelos LS, et al. Phosphoinositide 3-kinase g plays a critical role in bleomycin-induced pulmonary inflammation and fibrosis in mice. J Leukoc Biol 2011;89:269-82
-
(2011)
J Leukoc Biol
, vol.89
, pp. 269-282
-
-
Russo, R.C.1
Garcia, C.C.2
Barcelos, L.S.3
|