Role of matrix metaloproteases in idiopathic pulmonary fibrosis

Fibrogenesis and Tissue Repair

Volumn 5, Issue SUPPL.1, 2012, Pages

  Pardo, Annie ^a,b   Selman, Moisés ^a,b  

^a UNIVERSIDAD NACIONAL AUTÓNOMA DE MÉXICO   (Mexico)

^b INSTITUTO NACIONAL DE ENFERMEDADES RESPIRATORIAS   (Mexico)

Author keywords

[No Author keywords available]

Indexed keywords

COLLAGEN; GELATINASE B; GROWTH FACTOR; GROWTH FACTOR RECEPTOR; INTERSTITIAL COLLAGENASE; MATRILYSIN; MATRIX METALLOPROTEINASE; STROMELYSIN; THY 1 ANTIGEN;

ANGIOGENESIS; APOPTOSIS; ARTICLE; BASEMENT MEMBRANE; CELL ACTIVATION; CELL DAMAGE; CELL INTERACTION; CELL MIGRATION; CELL PROLIFERATION; EPITHELIAL MESENCHYMAL TRANSITION; EXTRACELLULAR MATRIX; FIBROBLAST; FIBROCYTE; FIBROSING ALVEOLITIS; HUMAN; LUNG ALVEOLUS EPITHELIUM; LUNG FIBROBLAST; LUNG PARENCHYMA; MESENCHYMAL STEM CELL; MYOFIBROBLAST; NONHUMAN; PATHOGENESIS; UPREGULATION;

EID: 84877043110     PISSN: None     EISSN: 17551536     Source Type: Journal    
DOI: 10.1186/1755-1536-5-S1-S9     Document Type: Article

References (39)

1. Pardo A, Selman M. Molecular mechanisms of pulmonary fibrosis. Front Biosci 2002, 7:d1743-1761. 10.2741/pardo, 12133818.
2. Selman M, Morrison LD, Noble PW, King T. Idiopathic interstitial pneumonias. Textbook of Respiratory Medicine 2010, 2:356-1397. Murray & Nadel's, 5.
3. Myers JL, Katzenstein AL. Beyond a consensus classification for idiopathic interstitial pneumonias: progress and controversies. Histopathology 2009, 54:90-103. 10.1111/j.1365-2559.2008.03173.x, 19054158.
4. Selman M, Pardo A. Role of epithelial cells in idiopathic pulmonary fibrosis: from innocent targets to serial killers. Proc Am Thorac Soc 2006, 3:364-372. 10.1513/pats.200601-003TK, 16738202.
5. Andersson-Sjöland A, de Alba CG, Nihlberg K, Becerril C, Ramírez R, Pardo A, Westergren-Thorsson G, Selman M. Fibrocytes are a potential source of lung fibroblasts in idiopathic pulmonary fibrosis. Int J Biochem Cell Biol 2008, 40:2129-2140. 10.1016/j.biocel.2008.02.012, 18374622.
6. King TE, Pardo A, Selman M. Idiopathic pulmonary fibrosis. Lancet 2011, 378:1949-1961. 10.1016/S0140-6736(11)60052-4, 21719092.
7. Horan GS, Wood S, Ona V, Li DJ, Lukashev ME, Weinreb PH, Simon KJ, Hahm K, Allaire NE, Rinaldi NJ, Goyal J, Feghali-Bostwick CA, Matteson EL, O'Hara C, Lafyatis R, Davis GS, Huang X, Sheppard D, Violette SM. Partial inhibition of integrin alpha[v]beta6 prevents pulmonary fibrosis without exacerbating inflammation. Am J Respir Crit Care Med 2008, 177:56-65.
8. Willis BC, Liebler JM, Luby-Phelps K, Nicholson AG, Crandall ED, du Bois RM, Borok Z. Induction of epithelial-mesenchymal transition in alveolar epithelial cells by transforming growth factor-beta1: potential role in idiopathic pulmonary fibrosis. Am J Pathol 2005, 166:1321-1332. 10.1016/S0002-9440(10)62351-6, 1606388, 15855634.
9. Kim KK, Kugler MC, Wolters PJ, Robillard L, Galvez MG, Brumwell AN, Sheppard D, Chapman HA. Alveolar epithelial cell mesenchymal transition develops in vivo during pulmonary fibrosis and is regulated by the extracellular matrix. Proc Natl Acad Sci USA 2006, 103:13180-13185. 10.1073/pnas.0605669103, 1551904, 16924102.
10. Larsson O, Diebold D, Fan D, Peterson M, Nho RS, Bitterman PB, Henke CA. Fibrotic myofibroblasts manifest genome-wide derangements of translational control. PLoS One 2008, 3:e3220. 10.1371/journal.pone.0003220, 2528966, 18795102.
11. Lee JM, Dedhar S, Kalluri R, Thompson EW. The epithelial-mesenchymal transition: new insights in signaling, development, and disease. J Cell Biol 2006, 172:973-981. 10.1083/jcb.200601018, 2063755, 16567498.
12. Orlichenko LS, Radisky DC. Matrix metalloproteinases stimulate epithelial-mesenchymal transition during tumor development. Clin Exp Metastasis 2008, 25:593-600. 10.1007/s10585-008-9143-9, 18286378.
13. Zheng G, Lyons JG, Tan TK, Wang Y, Hsu TT, Min D, Succar L, Rangan GK, Hu M, Henderson BR, Alexander SI, Harris DC. Disruption of E-cadherin by matrix metalloproteinase directly mediates epithelial-mesenchymal transition downstream of transforming growth factor-beta1 in renal tubular epithelial cells. Am J Pathol 2009, 175:580-591. 10.2353/ajpath.2009.080983, 2716958, 19590041.
14. Lin CY, Tsai PH, Kandaswami CC, Lee PP, Huang CJ, Hwang JJ, Lee MT. Matrix metalloproteinase-9 cooperates with transcription factor Snail to induce epithelial-mesenchymal transition. Cancer Sci 2011, 102:815-827. 10.1111/j.1349-7006.2011.01861.x, 21219539.
15. Rawlings ND, Morton FR, Barrett AJ. MEROPS: the peptidase database. Nucleic Acids Res 2006, 34:D270-D272. 10.1093/nar/gkj089, 1347452, 16381862.
16. Pardo A, Selman M, Kaminski N. Approaching the degradome in idiopathic pulmonary fibrosis. Int J Biochem Cell Biol 2008, 40:1141-1455. 10.1016/j.biocel.2007.11.020, 18207447.
17. Puente XS, Sanchez LM, Overall CM, Lopez-Otin C. Human and mouse proteases: a comparative genomic approach. Nat Rev Genet 2003, 4:544-58. 10.1038/nrg1111, 12838346.
18. Limb GA, Matter K, Murphy G, Cambrey AD, Bishop PN, Morris GE, Khaw PT. Matrix metalloproteinase-1 associates with intracellular organelles and confers resistance to lamin A/C degradation during apoptosis. Am J Pathol 2005, 166:1555-1563. 10.1016/S0002-9440(10)62371-1, 1606407, 15855654.
19. Wang W, Schulze CJ, Suarez-Pinzon WL, Sawicka J, Sawicki G, Schulz R. Intracellular action of matrix metalloproteinase-2 accounts for acute myocardial ischemia and reperfusion injury. Circulation 2002, 106:1543-1549. 10.1161/01.CIR.0000028818.33488.7B, 12234962.
20. Brinckerhoff CE, Matrisian LM. Matrix metalloproteinases: a tail of a frog that became a prince. Nat Rev Mol Cell Biol 2002, 3:207-215. 10.1038/nrm763, 11994741.
21. Folgueras AR, Pendas AM, Sanchez LM, Lopez-Otin C. Matrix metalloproteinases in cancer: from new functions to improved inhibition strategies. Int J Dev Biol 2004, 48:411-24. 10.1387/ijdb.041811af, 15349816.
22. Sternlicht MD, Werb Z. How matrix metalloproteinases regulate cell behavior. Annu Rev Cell Dev Biol 2001, 17:463-516. 10.1146/annurev.cellbio.17.1.463, 2792593, 11687497.
23. Zuo F, Kaminski N, Eugui E, Allard J, Yakhini Z, Ben-Dor A, Lollini L, Morris D, Kim Y, DeLustro B, Sheppard D, Pardo A, Selman M, Heller RA. Gene expression analysis reveals matrilysin as a key regulator of pulmonary fibrosis in mice and humans. Proc Natl Acad Sci USA 2002, 99:6292-6297. 10.1073/pnas.092134099, 122942, 11983918.
24. Segura-Valdez L, Pardo A, Gaxiola M, Uhal BD, Becerril C, Selman M. Upregulation of gelatinases A and B, collagenases 1 and 2, and increased parenchymal cell death in COPD. Chest 2000, 117:684-694. 10.1378/chest.117.3.684, 10712992.
25. Vincenti MP, Brinckerhoff CE. Transcriptional regulation of collagenase [MMP-1, MMP-13] genes in arthritis: integration of complex signaling pathways for the recruitment of gene-specific transcription factors. Arthritis Res 2002, 4:157-164. 10.1186/ar401, 128926, 12010565.
26. Fukuda Y, Ishizaki M, Kudoh S, Kitaichi M, Yamanaka N. Localization of matrix metalloproteinases-1, -2, and -9 and tissue inhibitor of metalloproteinase-2 in interstitial lung diseases. Lab Invest 1998, 78:687-698.
27. Selman M, Ruiz V, Cabrera S, Segura L, Ramírez R, Barrios R, Pardo A. TIMP-1, -2, -3 and -4 in idiopathic pulmonary fibrosis. A prevailing non degradative lung microenvironment?. Am J Physiol Lung Cell Mol Physiol 2000, 279:L562-L574.
28. Pilcher BK, Dumin JA, Sudbeck BD, Krane SM, Welgus HG, Parks WC. The activity of collagenase-1 is required for keratinocyte migration on a type I collagen matrix. J Cell Biol 1997, 137:1445-1457. 10.1083/jcb.137.6.1445, 2132537, 9182674.
29. Checa M, Ruiz V, Montaño M, Velázquez-Cruz R, Selman M, Pardo A. MMP-1 polymorphisms and the risk of idiopathic pulmonary fibrosis. Hum Genet 2008, 124:465-472. 10.1007/s00439-008-0571-z, 18853190.
30. Pardo A, Gibson K, Cisneros J, Richards TJ, Yang Y, Becerril C, Yousem S, Herrera I, Ruiz V, Selman M, Kaminski N. Up-regulation and profibrotic role of osteopontin in human idiopathic pulmonary fibrosis. PLoS Med 2005, 2:e251. 10.1371/journal.pmed.0020251, 1198037, 16128620.
31. Selman M, Pardo A, Barrera L, Estrada A, Watson SR, Wilson K, Aziz N, Kaminski N, Zlotnik A. Gene expression profiles distinguish idiopathic pulmonary fibrosis from hypersensitivity pneumonitis. Am J Respir Crit Care Med 2006, 173:188-198. 2662988, 16166619.
32. Agnihotri R, Crawford HC, Haro H, Matrisian LM, Havrda MC, Liaw L. Osteopontin, a novel substrate for matrix metalloproteinase-3 [stromelysin-1] and matrix metalloproteinase-7 [matrilysin]. J Biol Chem 2001, 276:28261-28267. 10.1074/jbc.M103608200, 11375993.
33. Melk A, Mansfield ES, Hsieh SC, Hernandez-Boussard T, Grimm P, Rayner DC, Halloran PF, Sarwal MM. Transcriptional analysis of the molecular basis of human kidney aging using cDNA microarray profiling. Kidney Int 2005, 68:2667-2679. 10.1111/j.1523-1755.2005.00738.x, 16316342.
34. Rosas IO, Richards TJ, Konishi K, Zhang Y, Gibson K, Lokshin AE, Lindell KO, Cisneros J, Macdonald SD, Pardo A, Sciurba F, Dauber J, Selman M, Gochuico BR, Kaminski N. MMP1 and MMP7 as potential peripheral blood biomarkers in idiopathic pulmonary fibrosis. PLoS Med 2008, 5:e93. 10.1371/journal.pmed.0050093, 2346504, 18447576.
35. Yamashita CM, Dolgonos L, Zemans RL, Young SK, Robertson J, Briones N, Suzuki T, Campbell MN, Gauldie J, Radisky DC, Riches DW, Yu G, Kaminski N, McCulloch CA, Downey GP. Matrix metalloproteinase 3 is a mediator of pulmonary fibrosis. Am J Pathol 2011, 179:1733-1745. 10.1016/j.ajpath.2011.06.041, 21871427.
36. García-de-Alba C, Becerril C, Ruiz V, González Y, Reyes S, García-Alvarez J, Selman M, Pardo A. Expression of matrix metalloproteases by fibrocytes. Possible role in migration and homing. Am J Respir Crit Care Med 2010, 182:1144-1152. 10.1164/rccm.201001-0028OC, 20622038.
37. Hagood JS, Prabhakaran P, Kumbla P, Salazar L, MacEwen MW, Barker TH, Ortiz LA, Schoeb T, Siegal GP, Alexander CB, Pardo A, Selman M. Loss of fibroblast Thy-1 expression correlates with lung fibrogenesis. Am J Pathol 2005, 167:365-379. 10.1016/S0002-9440(10)62982-3, 1603564, 16049324.
38. Ramírez G, Hagood JS, Sanders Y, Ramírez R, Becerril C, Segura L, Barrera L, Selman M, Pardo A. Absence of Thy-1 results in TGF-β induced MMP-9 expression and confers a profibrotic phenotype to human lung fibroblasts. Lab Invest 2011, 91:1206-1218. 10.1038/labinvest.2011.80, 21577212.
39. Yu Q, Stamenkovic I. Cell surface-localized matrix metalloproteinase-9 proteolytically activates TGF-β and promotes tumor invasion and angiogenesis. Genes Dev 2000, 14:163-176. 316345, 10652271.