Activation of somatostatin receptors attenuates pulmonary fibrosis

Thorax

Volumn 63, Issue 3, 2008, Pages 251-258

  Borie, R ^a,b   Fabre, A ^a,b,c   Prost, F ^a,b   Marchal Somme, J ^a,b   Lebtahi, R ^d   Marchand Adam, S ^a,b,e   Aubier, M ^a,b,e   Soler, P ^a,b   Crestani, B ^a,b,c,e  

^a INSERM   (France)

^b UNIVERSITÉ PARIS DESCARTES   (France)

^c BICHAT HOSPITAL   (France)

^d GHPS Saint Joseph   (France)

^e Service de Pneumologie A   (France)

Author keywords

[No Author keywords available]

Indexed keywords

BLEOMYCIN; BROXURIDINE; COLLAGEN TYPE 1; CONNECTIVE TISSUE GROWTH FACTOR; KERATINOCYTE GROWTH FACTOR; MESSENGER RNA; PASIREOTIDE; SCATTER FACTOR; SODIUM CHLORIDE; SOMATOSTATIN RECEPTOR 1; SOMATOSTATIN RECEPTOR 2; SOMATOSTATIN RECEPTOR 3; SOMATOSTATIN RECEPTOR 4; SOMATOSTATIN RECEPTOR 5; TRANSFORMING GROWTH FACTOR BETA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ATTENUATION; CELL ACTIVATION; CELL CULTURE; CELL STIMULATION; CONTROLLED STUDY; DRUG ACTIVATION; DRUG HALF LIFE; DRUG MECHANISM; HUMAN; HUMAN CELL; HUMAN TISSUE; IN VITRO STUDY; INFLAMMATORY CELL; LUNG; LUNG EXAMINATION; LUNG FIBROBLAST; LUNG FIBROSIS; LUNG LAVAGE; MALE; MOUSE; MOUSE STRAIN; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SURVIVAL;

ANIMALS; ANTIBIOTICS, ANTINEOPLASTIC; BLEOMYCIN; IMMUNOHISTOCHEMISTRY; MALE; MICE; MICE, INBRED C57BL; PULMONARY FIBROSIS; RECEPTORS, SOMATOSTATIN; RNA, MESSENGER; SOMATOSTATIN; TRANSFORMING GROWTH FACTOR ALPHA;

EID: 40649115985     PISSN: 00406376     EISSN: None     Source Type: Journal    
DOI: 10.1136/thx.2007.078006     Document Type: Article

References (42)

1. Marchal-Somme J, Uzunhan Y, Marchand-Adam S, et al. Cutting edge: Nonproliferating mature immune cells form a novel type of organized lymphoid structure in idiopathic pulmonary fibrosis. J Immunol 2006;176:5735-9.
2. Selman M, Thannickal VJ, Pardo A, et al. Idiopathic pulmonary fibrosis. Pathogenesis and therapeutic approaches. Drugs 2004;64:405-30.
3. Lebtahi R, Moreau S, Marchand-Adam S, et al. Increased uptake of 111In-octreotide in idiopathic pulmonary fibrosis. J Nucl Med 2006;47:1281-7.
4. Lahlou H, Saint-Laurent N, Estève JP, et al. SST2 somatostatin receptor inhibits cell proliferation through Ras-, rap1-, and B-Raf-dependent ERK2 activation. J Biol Chem 2003;278:39356-71.
5. Gunal AI, Duman S, Sen S, et al. By reducing TGF beta 1, octreotide lessens the peritoneal derangements induced by a high glucose solution. J Nephrol 2001;14:184-9.
6. Wang J, Zheng H, Hauer-Jensen M. Influence of short-term octreotide administration on chronic tissue injury, transforming growth factor beta (TGF-beta) overexpression, and collagen accumulation in irradiated rat intestine. J Pharmacol Exp Ther 2001;297:35-42.
7. Valatas V, Kolios G, Manousou P, et al. Octreotide regulates CC but not CXC LPS-induced chemokine secretion in rat Kupffer cells. Br J Pharmacol 2004;141:477-87.
8. Bruns C, Lewis I, Briner U, et al. SOM230: a novel somatostatin peptidomimetic with broad somatotropin release inhibiting factor (SRIF) receptor binding and a unique antisecretory profile. Eur J Endocrinol 2002;146:707-16.
9. Silva AP, Bethmann K, Raulf F, et al. Regulation of ghrelin secretion by somatostatin analogs in rats. Eur J Endocrinol 2005;152:887-94.
10. Inoshima I, Kuwano K, Hamada N, et al. Anti-monocyte chemoattractant protein-1 gene therapy attenuates pulmonary fibrosis in mice. Am J Physiol Lung Cell Mol Physiol 2004;286:L1038-44.
11. Marchand-Adam S, Fabre A, Mailleux AA, et al. Defect of pro-hepatocyte growth factor activation by fibroblasts in idiopathic pulmonary fibrosis. Am J Respir Crit Care Med 2006;174:58-66.
12. American Thoracic Society/European Respiratory Society international multidisciplinary consensus classification of the idiopathic interstitial pneumonias. Am J Respir Crit Care Med 2002;165:277-304.
13. Olias G, Viollet C, Kusserow H, et al. Regulation and function of somatostatin receptors. J Neurochem 2004;89:1057-91.
14. Domen SP, Hofland LJ, van Hagen PM, et al. Somatostatin receptors in the haematopoietic system. Eur J Endocrinol 2000;143(Suppl 1):S9-14.
15. Blum AM, Metwali A, Mathew RC, et al. Granuloma T lymphocytes in murine schistosomiasis mansoni have somatostatin receptors and respond to somatostatin with decreased IFN-γ secretion. J Immunol 1992;149:3621-6.
16. Elliott DE, Metwali A, Blum AM, et al. T lymphocytes isolated from the hepatic granulomas of schistosome-infected mice express somatostatin receptor subtype II (SSTR2) messenger RNA. J Immunol 1994;153:1180-1.
17. Talme T, Ivanoff J, Sundqvist KG. Somatostatin is a specific inhibitor of SDF-1alpha-induced T cell infiltration. Clin Exp Immunol 2004;135:434-9.
18. Chao TC, Cheng HP, Walter RJ. Somatostatin and macrophage function: modulation of hydrogen peroxide, nitric oxide and tumor necrosis factor release. Regul Pept 1995;58:1-10.
19. Kolasinski SL, Haines KA, Siegel EL, et al. Neuropeptides and inflammation. A somatostatin analog as a selective antagonist of neutrophil activation by substance P. Arthritis Rheum 1992;35:369-75.
20. Adeyemi EO, Savage AP, Bloom SR, et al. Somatostatin inhibits neutrophil elastase release in vitro. Peptides 1990;11:869-71.
21. Tracy TF, Tector AJ, Goerke ME, et al. Somatostatin analogue (octreotide) inhibits bile duct epithelial cell proliferation and fibrosis after extrahepatic biliary obstruction. Am J Pathol 1993;143:1574-8.
22. Fort J, Oberti F, Pilette C, et al. Antifibrotic and hemodynamic effects of the early and chronic administration of octreotide in two models of liver fibrosis in rats. Hepatology 1998;28:1525-31.
23. Wang J, Zheng H, Sung CC, et al. The synthetic somatostatin analogue, octreotide, ameliorates acute and delayed intestinal radiation injury. Int J Radiat Oncol Biol Phys 1999;45:1289-96.
24. Mansy SS, Yehia HA, Hassan MM, et al. Octreotide decreases connective tissue formation and improves vascular changes associated with hepatic schistosomiasis. J Egypt Soc Parasitol 1998;28:23-44.
25. Guillermet-Guibert J, Saint-Laurent N, Davenne L, et al. Novel synergistic mechanism for sst2 somatostatin and TNFalpha receptors to induce apoptosis: crosstalk between NF-kappaB and JNK pathways. Cell Death Differ 2007;14:197-208.
26. Priestley GC, Aldridge RD, Sime PJ, et al. Skin fibroblast activity in pretibial myxoedema and the effect of octreotide (Sandostatin) in vitro. Br J Dermatol 1994;131:52-6.
27. Pasquali D, Vassallo P, Esposito D, et al. Somatostatin gene receptor expression and inhibitory effects of octreotide on primary cultures of orbital fibroblasts from Grave's ophtalmopathy. J Mol Endocrinol 2000;25:63-71.
28. Xidakis C, Ljumovic D, Manousou P, et al. Production of pro- and anti-fibrotic agents by rat Kupffer cells; the effect of octreotide. Dig Dis Sci 2005;50:935-41.
29. Puente E, Saint-Laurent N, Torrisani J, et al. Transcriptional activation of mouse sst2 somatostatin receptor promoter by transforming growth factor-beta. involvement of Smad4. J Biol Chem 2001;276:13461-8.
30. Lattuada D, Casnici C, Crotta K, et al. Inhibitory effect of pasireotide and octreotide on lymphocyte activation. J Neuroimmunol 2007;182:153-9.
31. Armani C, Catalini E, Baibarini A, et al. Expression, pharmacology, and functional role of somatostatin receptor subtypes 1 and 2 in human macrophages. J Leukoc Biol 2007;81:845-55.
32. Carolan EJ, Casale TB. Effects of neuropeptides on neutrophil migration through noncellular and endothelial barriers. J Allergy Clin Immunol 1993;92:589-98.
33. Frazier K, Williams S, Kothapalli D, et al. Stimulation of fibroblast cell growth, matrix production, and granulation tissue formation by connective tissue growth factor. J Invest Dermatol 1996;107:404- 11.
34. Song SH, Leng XS, Li T, et al. The effect of somatostatin analogue on expression of connective tissue growth factor gene of rat hepatic stellate cells. Zhonghua Wai Ke Za Zhi 2004;42:551-3.
35. Ware LB, Matthay MA. Keratinocyte and hepatocyte growth factors in the lung: roles in lung development, inflammation, and repair. Am J Physiol Lung Cell Mol Physiol 2002;282:L924-40.
36. Marchand-Adam S, Marchal J, Cohen M, et al. Defect of hepatocyte growth factor secretion by fibroblasts in idiopathic pulmonary fibrosis. Am J Respir Crit Care Med 2003;168:1156-61.
37. Marchand-Adam S, Plantier L, Bernuau D, et al. Keratinocyte growth factor expression by fibroblasts in pulmonary fibrosis: poor response to interleukin-1beta. Am J Respir Cell Mol Biol 2005;32:470-7.
38. Adams RL, Adams IP, Lindow SW, et al. Inhibition of endothelial proliferation by the somatostatin analogue SOM230. Clin Endocrinol (Oxf) 2004;61:431-6.
39. Jia WD, Xu GL, Xu RN, et al. Octreotide acts as an antitumor angiogenesis compound and suppresses tumor growth in nude mice bearing human hepatocellular carcinoma xenografts. J Cancer Res Clin Oncol 2003;129:327-34.
40. Renzoni EA, Walsh DA, Salmon M, et al. Interstitial vascularity in fibrosing alveolitis. Am J Respir Crit Care Med 2003;167:438-43.
41. Hamada N, Kuwano K, Yamada M, et al. Anti-vascular endothelial growth factor gene therapy attenuates lung injury and fibrosis in mice. J Immunol 2005;175:1224-31.
42. Reynaert H, Rombouts K, Jia Y, et al. Somatostatin at nanomolar concentration reduces collagen I and III synthesis by, but not proliferation of activated rat hepatic stellate cells. Br J Pharmacol 2005;146:77-88.