-
1
-
-
0015489274
-
Bilateral adrenalectomy for palliative treatment of prostatic cancer
-
Mahoney EM, Harrison JH. Bilateral adrenalectomy for palliative treatment of prostatic cancer. J Urol 1972; 108: 936-938.
-
(1972)
J Urol
, vol.108
, pp. 936-938
-
-
Mahoney, E.M.1
Harrison, J.H.2
-
2
-
-
1842457650
-
Antiandrogen withdrawal alone or in combination with ketoconazole in androgen-independent prostate cancer patients: A phase III trial (CALGB 9583)
-
DOI 10.1200/JCO.2004.06.037
-
Small EJ, Halabi S, Dawson NA, Stadler WM, Rini BI, Picus J et al. Antiandrogen withdrawal alone or in combination with ketoconazole in androgen-indepen-dent prostate cancer patients: a phase III trial (CALGB 9583). J Clin Oncol 2004; 22: 1025-1033. (Pubitemid 41095034)
-
(2004)
Journal of Clinical Oncology
, vol.22
, Issue.6
, pp. 1025-1033
-
-
Small, E.J.1
Halabi, S.2
Dawson, N.A.3
Stadler, W.M.4
Rini, B.I.5
Picus, J.6
Gable, P.7
Torti, F.M.8
Kaplan, E.9
Vogelzang, N.J.10
-
4
-
-
72549108829
-
Phase II study of androgen synthesis inhibition with ketoconazole, hydrocortisone, and dutasteride in asymptomatic castration-resistant prostate cancer
-
Taplin ME, Regan MM, Ko YJ, Bubley GJ, Duggan SE, Werner L et al. Phase II study of androgen synthesis inhibition with ketoconazole, hydrocortisone, and dutasteride in asymptomatic castration-resistant prostate cancer. Clin Cancer Res 2009; 15: 7099-7105.
-
(2009)
Clin Cancer Res
, vol.15
, pp. 7099-7105
-
-
Taplin, M.E.1
Regan, M.M.2
Ko, Y.J.3
Bubley, G.J.4
Duggan, S.E.5
Werner, L.6
-
5
-
-
0032497522
-
Bilateral orchiectomy with or without flutamide for metastatic prostate cancer
-
DOI 10.1056/NEJM199810083391504
-
Eisenberger MA, Blumenstein BA, Crawford ED, Miller G, McLeod DG, Loehrer PJ et al. Bilateral orchiectomy with or without flutamide for metastatic prostate cancer. N Engl J Med 1998; 339: 1036-1042. (Pubitemid 28457865)
-
(1998)
New England Journal of Medicine
, vol.339
, Issue.15
, pp. 1036-1042
-
-
Eisenberger, M.A.1
Blumenstein, B.A.2
Crawford, E.D.3
Miller, G.4
McLeod, D.G.5
Loehrer, P.J.6
Wilding, G.7
Sears, K.8
Culkin, D.J.9
Thompson Jr., I.M.10
Bueschen, A.J.11
Lowe, B.A.12
-
6
-
-
0037099723
-
Systematic review and meta-analysis of monotherapy compared with combined androgen blockade for patients with advanced prostate carcinoma
-
DOI 10.1002/cncr.10647
-
Samson DJ, Seidenfeld J, Schmitt B, Hasselblad V, Albertsen PC, Bennett CL et al. Systematic review and meta-analysis of monotherapy compared with combined androgen blockade for patients with advanced prostate carcinoma. Cancer 2002; 95: 361-376. (Pubitemid 34787603)
-
(2002)
Cancer
, vol.95
, Issue.2
, pp. 361-376
-
-
Samson, D.J.1
Seidenfeld, J.2
Schmitt, B.3
Hasselblad, V.4
Albertsen, P.C.5
Bennett, C.L.6
Wilt, T.J.7
Aronson, N.8
-
7
-
-
0343698426
-
Androgen receptor status in localized and locally progressive hormone refractory human prostate cancer
-
Ruizeveld de Winter JA, Janssen PJ, Sleddens HM, Verleun-Mooijman MC, Trapman J, Brinkmann AO et al. Androgen receptor status in localized and locally progressive hormone refractory human prostate cancer. Am J Pathol 1994; 144: 735-746. (Pubitemid 24172062)
-
(1994)
American Journal of Pathology
, vol.144
, Issue.4
, pp. 735-746
-
-
Ruizeveld De Winter, J.A.1
Janssen, P.J.A.2
Sleddens, H.M.E.B.3
Verleun-Mooijman, M.C.T.4
Trapman, J.5
Brinkmann, A.O.6
Santerse, A.B.7
Schroder, F.H.8
Van Der Kwast, T.H.9
-
8
-
-
0029011116
-
Mutation of the androgen-receptor gene in metastatic androgen-independent prostate cancer
-
Taplin ME, Bubley GJ, Shuster TD, Frantz ME, Spooner AE, Ogata GK et al. Mutation of the androgen-receptor gene in metastatic androgen-independent prostate cancer. N Engl J Med 1995; 332: 1393-1398.
-
(1995)
N Engl J Med
, vol.332
, pp. 1393-1398
-
-
Taplin, M.E.1
Bubley, G.J.2
Shuster, T.D.3
Frantz, M.E.4
Spooner, A.E.5
Ogata, G.K.6
-
9
-
-
1542574202
-
Gene Expression Analysis of Human Prostate Carcinoma during Hormonal Therapy Identifies Androgen-Responsive Genes and Mechanisms of Therapy Resistance
-
Holzbeierlein J, Lal P, LaTulippe E, Smith A, Satagopan J, Zhang L et al. Gene expression analysis of human prostate carcinoma during hormonal therapy identifies androgen-responsive genes and mechanisms of therapy resistance. Am J Pathol 2004; 164: 217-227. (Pubitemid 38364606)
-
(2004)
American Journal of Pathology
, vol.164
, Issue.1
, pp. 217-227
-
-
Holzbeierlein, J.1
Lal, P.2
LaTulippe, E.3
Smith, A.4
Satagopan, J.5
Zhang, L.6
Ryan, C.7
Smith, S.8
Scher, H.9
Scardino, P.10
Reuter, V.11
Gerald, W.L.12
-
10
-
-
33645056171
-
Increased expression of genes converting adrenal androgens to testosterone in androgen-independent prostate cancer
-
Stanbrough M, Bubley GJ, Ross K, Golub TR, Rubin MA, Penning TM et al. Increased expression of genes converting adrenal androgens to testosterone in androgen-independent prostate cancer. Cancer Res 2006; 66: 2815-2825.
-
(2006)
Cancer Res
, vol.66
, pp. 2815-2825
-
-
Stanbrough, M.1
Bubley, G.J.2
Ross, K.3
Golub, T.R.4
Rubin, M.A.5
Penning, T.M.6
-
11
-
-
0028944138
-
In vivo amplification of the androgen receptor gene and progression of human prostate cancer
-
Visakorpi T, Hyytinen E, Koivisto P, Tanner M, Keinanen R, Palmberg C et al. In vivo amplification of the androgen receptor gene and progression of human prostate cancer. Nat Genet 1995; 9: 401-406.
-
(1995)
Nat Genet
, vol.9
, pp. 401-406
-
-
Visakorpi, T.1
Hyytinen, E.2
Koivisto, P.3
Tanner, M.4
Keinanen, R.5
Palmberg, C.6
-
12
-
-
0033152164
-
Selection for androgen receptor mutations in prostate cancers treated with androgen antagonist
-
Taplin ME, Bubley GJ, Ko YJ, Small EJ, Upton M, Rajeshkumar B et al. Selection for androgen receptor mutations in prostate cancers treated with androgen antagonist. Cancer Res 1999; 59: 2511-2515. (Pubitemid 29269089)
-
(1999)
Cancer Research
, vol.59
, Issue.11
, pp. 2511-2515
-
-
Taplin, M.-E.1
Bubley, G.J.2
Ko, Y.-J.3
Small, E.J.4
Upton, M.5
Rajeshkumar, B.6
Balk, S.P.7
-
13
-
-
0032535307
-
Androgen receptor expression in androgen-independent prostate cancer is associated with increased expression of androgen-regulated genes
-
Gregory CW, Hamil KG, Kim D, Hall SH, Pretlow TG, Mohler JL et al. Androgen receptor expression in androgen-independent prostate cancer is associated with increased expression of androgen-regulated genes. Cancer Res 1998; 58: 5718-5724. (Pubitemid 29006412)
-
(1998)
Cancer Research
, vol.58
, Issue.24
, pp. 5718-5724
-
-
Gregory, C.W.1
Hamil, K.G.2
Kim, D.3
Hall, S.H.4
Pretlow, T.G.5
Mohler, J.L.6
French, F.S.7
-
14
-
-
1842612441
-
Molecular determinants of resistance to antiandrogen therapy
-
DOI 10.1038/nm972
-
Chen CD, Welsbie DS, Tran C, Baek SH, Chen R, Vessella R et al. Molecular determinants of resistance to antiandrogen therapy. Nat Med 2004; 10: 33-39. (Pubitemid 38524696)
-
(2004)
Nature Medicine
, vol.10
, Issue.1
, pp. 33-39
-
-
Chen, C.D.1
Welsbie, D.S.2
Tran, C.3
Baek, S.H.4
Chen, R.5
Vessella, R.6
Rosenfeld, M.G.7
Sawyers, C.L.8
-
15
-
-
0028272478
-
Androgen-independent cancer progression and bone metastasis in the LNCaP model of human prostate cancer
-
Thalmann GN, Anezinis PE, Chang SM, Zhau HE, Kim EE, Hopwood VL et al. Androgen-independent cancer progression and bone metastasis in the LNCaP model of human prostate cancer. Cancer Res 1994; 54: 2577-2581. (Pubitemid 24173741)
-
(1994)
Cancer Research
, vol.54
, Issue.10
, pp. 2577-2581
-
-
Thalmann, G.N.1
Anezinis, P.E.2
Chang, S.-M.3
Zhau, H.E.4
Kim, E.E.5
Hopwood, V.L.6
Pathak, S.7
Von Eschenbach, A.C.8
Chung, L.W.K.9
-
16
-
-
0036170838
-
Disruption of androgen receptor function inhibits proliferation of androgen-refractory prostate cancer cells
-
Zegarra-Moro OL, Schmidt LJ, Huang H, Tindall DJ. Disruption of androgen receptor function inhibits proliferation of androgen-refractory prostate cancer cells. Cancer Res 2002; 62: 1008-1013. (Pubitemid 34160279)
-
(2002)
Cancer Research
, vol.62
, Issue.4
, pp. 1008-1013
-
-
Zegarra-Moro, O.L.1
Schmidt, L.J.2
Huang, H.3
Tindall, D.J.4
-
17
-
-
33746661499
-
Androgen receptor remains critical for cell-cycle progression in androgen-independent CWR22 prostate cancer cells
-
DOI 10.2353/ajpath.2006.051047
-
Yuan X, Li T, Wang H, Zhang T, Barua M, Borgesi RA et al. Androgen receptor remains critical for cell-cycle progression in androgen-independent CWR22 prostate cancer cells. Am J Pathol 2006; 169: 682-696. (Pubitemid 44156324)
-
(2006)
American Journal of Pathology
, vol.169
, Issue.2
, pp. 682-696
-
-
Yuan, X.1
Li, T.2
Wang, H.3
Zhang, T.4
Barua, M.5
Borgesi, R.A.6
Bubley, G.J.7
Lu, M.L.8
Balk, S.P.9
-
18
-
-
0842311632
-
The Androgen Axis in Recurrent Prostate Cancer
-
DOI 10.1158/1078-0432.CCR-1146-03
-
Mohler JL, Gregory CW, Ford 3rd OH, Kim D, Weaver CM, Petrusz P et al. The androgen axis in recurrent prostate cancer. Clin Cancer Res 2004; 10: 440-448. (Pubitemid 38173980)
-
(2004)
Clinical Cancer Research
, vol.10
, Issue.2
, pp. 440-448
-
-
Mohler, J.L.1
Gregory, C.W.2
Ford III, H.3
Kim, D.4
Weaver, C.M.5
Petrusz, P.6
Wilson, E.M.7
French, F.S.8
-
19
-
-
27644452640
-
Testosterone and dihydrotestosterone tissue levels in recurrent prostate cancer
-
DOI 10.1158/1078-0432.CCR-05-0525
-
Titus MA, Schell MJ, Lih FB, Tomer KB, Mohler JL. Testosterone and dihy-drotestosterone tissue levels in recurrent prostate cancer. Clin Cancer Res 2005; 11: 4653-4657. (Pubitemid 41557182)
-
(2005)
Clinical Cancer Research
, vol.11
, Issue.13
, pp. 4653-4657
-
-
Titus, M.A.1
Schell, M.J.2
Lih, F.B.3
Tomer, K.B.4
Mohler, J.L.5
-
20
-
-
49249119358
-
Maintenance of intratumoral androgens in metastatic prostate cancer: A mechanism for castration-resistant tumor growth
-
Montgomery RB, Mostaghel EA, Vessella R, Hess DL, Kalhorn TF, Higano CS et al. Maintenance of intratumoral androgens in metastatic prostate cancer: a mechanism for castration-resistant tumor growth. Cancer Res 2008; 68: 4447-4454.
-
(2008)
Cancer Res
, vol.68
, pp. 4447-4454
-
-
Montgomery, R.B.1
Mostaghel, E.A.2
Vessella, R.3
Hess, D.L.4
Kalhorn, T.F.5
Higano, C.S.6
-
21
-
-
80053940699
-
Intratumoral androgen biosynthesis in prostate cancer patho-genesis and response to therapy
-
Cai C, Balk SP. Intratumoral androgen biosynthesis in prostate cancer patho-genesis and response to therapy. Endocr Relat Cancer 2011; 18: R175-R182.
-
(2011)
Endocr Relat Cancer
, vol.18
-
-
Cai, C.1
Balk, S.P.2
-
22
-
-
84872078210
-
Abiraterone in metastatic prostate cancer without previous chemotherapy
-
Ryan CJ, Smith MR, de Bono JS, Molina A, Logothetis CJ, de Souza P et al. Abiraterone in metastatic prostate cancer without previous chemotherapy. N Engl J Med 2013; 368: 138-148.
-
(2013)
N Engl J Med
, vol.368
, pp. 138-148
-
-
Ryan, C.J.1
Smith, M.R.2
De Bono, J.S.3
Molina, A.4
Logothetis, C.J.5
De Souza, P.6
-
23
-
-
84866770294
-
Increased survival with enzalutamide in prostate cancer after chemotherapy
-
Scher HI, Fizazi K, Saad F, Taplin ME, Sternberg CN, Miller K et al. Increased survival with enzalutamide in prostate cancer after chemotherapy. N Engl J Med 2012; 367: 1187-1197.
-
(2012)
N Engl J Med
, vol.367
, pp. 1187-1197
-
-
Scher, H.I.1
Fizazi, K.2
Saad, F.3
Taplin, M.E.4
Sternberg, C.N.5
Miller, K.6
-
24
-
-
79957443342
-
Abiraterone and increased survival in metastatic prostate cancer
-
de Bono JS, Logothetis CJ, Molina A, Fizazi K, North S, Chu L et al. Abiraterone and increased survival in metastatic prostate cancer. N Engl J Med 2011; 364: 1995-2005.
-
(2011)
N Engl J Med
, vol.364
, pp. 1995-2005
-
-
De Bono, J.S.1
Logothetis, C.J.2
Molina, A.3
Fizazi, K.4
North, S.5
Chu, L.6
-
25
-
-
0034714276
-
Structural evidence for ligand specificity in the binding domain of the human androgen receptor. Implications for pathogenic gene mutations
-
Matias PM, Donner P, Coelho R, Thomaz M, Peixoto C, Macedo S et al. Structural evidence for ligand specificity in the binding domain of the human androgen receptor. Implications for pathogenic gene mutations. J Biol Chem 2000; 275: 26164-26171.
-
(2000)
J Biol Chem
, vol.275
, pp. 26164-26171
-
-
Matias, P.M.1
Donner, P.2
Coelho, R.3
Thomaz, M.4
Peixoto, C.5
Macedo, S.6
-
26
-
-
0035942197
-
Crystallographic structures of the ligand-binding domains of the androgen receptor and its T877A mutant complexed with the natural agonist dihydrotestosterone
-
DOI 10.1073/pnas.081565498
-
Sack JS, Kish KF, Wang C, Attar RM, Kiefer SE, An Y et al. Crystallographic structures of the ligand-binding domains of the androgen receptor and its T877A mutant complexed with the natural agonist dihydrotestosterone. Proc Natl Acad Sci USA 2001; 98: 4904-4909. (Pubitemid 32397055)
-
(2001)
Proceedings of the National Academy of Sciences of the United States of America
, vol.98
, Issue.9
, pp. 4904-4909
-
-
Sack, J.S.1
Kish, K.F.2
Wang, C.3
Attar, R.M.4
Kiefer, S.E.5
An, Y.6
Wu, G.Y.7
Scheffler, J.E.8
Salvati, M.E.9
Krystek Jr., S.R.10
Weinmann, R.11
Einspahr, H.M.12
-
27
-
-
8344226282
-
Structural basis for androgen receptor interdomain and coactivator interactions suggests a transition in nuclear receptor activation function dominance
-
DOI 10.1016/j.molcel.2004.09.036, PII S109727650400588X
-
He B, Gampe Jr. RT, Kole AJ, Hnat AT, Stanley TB, An G et al. Structural basis for androgen receptor interdomain and coactivator interactions suggests a transition in nuclear receptor activation function dominance. Mol Cell 2004; 16: 425-438. (Pubitemid 39504796)
-
(2004)
Molecular Cell
, vol.16
, Issue.3
, pp. 425-438
-
-
He, B.1
Gampe Jr., R.T.2
Kole, A.J.3
Hnat, A.T.4
Stanley, T.B.5
An, G.6
Stewart, E.L.7
Kalman, R.I.8
Minges, J.T.9
Wilson, E.M.10
-
28
-
-
19344376991
-
Recognition and accommodation at the androgen receptor coactivator binding interface
-
Hur E, Pfaff SJ, Payne ES, Gron H, Buehrer BM, Fletterick RJ. Recognition and accommodation at the androgen receptor coactivator binding interface. PLoS Biol 2004; 2: E274.
-
(2004)
PLoS Biol
, vol.2
-
-
Hur, E.1
Pfaff, S.J.2
Payne, E.S.3
Gron, H.4
Buehrer, B.M.5
Fletterick, R.J.6
-
29
-
-
22244455430
-
The structural basis of androgen receptor activation: Intramolecular and intermolecular amino-carboxy interactions
-
DOI 10.1073/pnas.0408819102
-
Schaufele F, Carbonell X, Guerbadot M, Borngraeber S, Chapman MS, Ma AA et al. The structural basis of androgen receptor activation: intramolecular and intermolecular amino-carboxy interactions. Proc Natl Acad Sci USA 2005; 102: 9802-9807. (Pubitemid 40993649)
-
(2005)
Proceedings of the National Academy of Sciences of the United States of America
, vol.102
, Issue.28
, pp. 9802-9807
-
-
Schaufele, F.1
Carbonell, X.2
Guerbadot, M.3
Borngraeber, S.4
Chapman, M.S.5
Ma, A.A.K.6
Miner, J.N.7
Diamond, M.I.8
-
30
-
-
34247146786
-
Compartmentalization of androgen receptor protein-protein interactions in living cells
-
DOI 10.1083/jcb.200609178
-
van Royen ME, Cunha SM, Brink MC, Mattern KA, Nigg AL, Dubbink HJ et al. Compartmentalization of androgen receptor protein-protein interactions in living cells. J Cell Biol 2007; 177: 63-72. (Pubitemid 46588402)
-
(2007)
Journal of Cell Biology
, vol.177
, Issue.1
, pp. 63-72
-
-
Van Royen, M.E.1
Cunha, S.M.2
Brink, M.C.3
Mattern, K.A.4
Nigg, A.L.5
Dubbink, H.J.6
Verschure, P.J.7
Trapman, J.8
Houtsmuller, A.B.9
-
31
-
-
84863111874
-
Step-wise androgen receptor dimerization
-
van Royen ME, van Cappellen WA, de Vos C, Houtsmuller AB, Trapman J. Step-wise androgen receptor dimerization. J Cell Sci 2012; 125: 1970-1979.
-
(2012)
J Cell Sci
, vol.125
, pp. 1970-1979
-
-
Van Royen, M.E.1
Van Cappellen, W.A.2
De Vos, C.3
Houtsmuller, A.B.4
Trapman, J.5
-
32
-
-
33847224474
-
Ligand-specific dynamics of the androgen receptor at its response element in living cells
-
Klokk TI, Kurys P, Elbi C, Nagaich AK, Hendarwanto A, Slagsvold T et al. Ligand-specific dynamics of the androgen receptor at its response element in living cells. Mol Cell Biol 2007; 27: 1823-1843.
-
(2007)
Mol Cell Biol
, vol.27
, pp. 1823-1843
-
-
Klokk, T.I.1
Kurys, P.2
Elbi, C.3
Nagaich, A.K.4
Hendarwanto, A.5
Slagsvold, T.6
-
33
-
-
40849085514
-
FoxA1 Translates Epigenetic Signatures into Enhancer-Driven Lineage-Specific Transcription
-
DOI 10.1016/j.cell.2008.01.018, PII S0092867408001189
-
Lupien M, Eeckhoute J, Meyer CA, Wang Q, Zhang Y, Li W et al. FoxA1 translates epigenetic signatures into enhancer-driven lineage-specific transcription. Cell 2008; 132: 958-970. (Pubitemid 351391952)
-
(2008)
Cell
, vol.132
, Issue.6
, pp. 958-970
-
-
Lupien, M.1
Eeckhoute, J.2
Meyer, C.A.3
Wang, Q.4
Zhang, Y.5
Li, W.6
Carroll, J.S.7
Liu, X.S.8
Brown, M.9
-
34
-
-
77950262538
-
Nucleosome dynamics define transcriptional enhancers
-
He HH, Meyer CA, Shin H, Bailey ST, Wei G, Wang Q et al. Nucleosome dynamics define transcriptional enhancers. Nat Genet 2010; 42: 343-347.
-
(2010)
Nat Genet
, vol.42
, pp. 343-347
-
-
He, H.H.1
Meyer, C.A.2
Shin, H.3
Bailey, S.T.4
Wei, G.5
Wang, Q.6
-
35
-
-
84857360697
-
Post-translational modification of the androgen receptor
-
Gioeli D, Paschal BM. Post-translational modification of the androgen receptor. Mol Cell Endocrinol 2012; 352: 70-78.
-
(2012)
Mol Cell Endocrinol
, vol.352
, pp. 70-78
-
-
Gioeli, D.1
Paschal, B.M.2
-
36
-
-
0036208492
-
Formation of the androgen receptor transcription complex
-
DOI 10.1016/S1097-2765(02)00471-9
-
Shang Y, Myers M, Brown M. Formation of the androgen receptor transcription complex. Mol Cell 2002; 9: 601-610. (Pubitemid 34273790)
-
(2002)
Molecular Cell
, vol.9
, Issue.3
, pp. 601-610
-
-
Shang, Y.1
Myers, M.2
Brown, M.3
-
37
-
-
67650758019
-
Androgen receptor regulates a distinct transcription program in androgen-independent prostate cancer
-
Wang Q, Li W, Zhang Y, Yuan X, Xu K, Yu J et al. Androgen receptor regulates a distinct transcription program in androgen-independent prostate cancer. Cell 2009; 138: 245-256.
-
(2009)
Cell
, vol.138
, pp. 245-256
-
-
Wang, Q.1
Li, W.2
Zhang, Y.3
Yuan, X.4
Xu, K.5
Yu, J.6
-
38
-
-
79960071366
-
The androgen receptor fuels prostate cancer by regulating central metabolism and biosynthesis
-
Massie CE, Lynch A, Ramos-Montoya A, Boren J, Stark R, Fazli L et al. The androgen receptor fuels prostate cancer by regulating central metabolism and biosynthesis. EMBO J 2011; 30: 2719-2733.
-
(2011)
EMBO J
, vol.30
, pp. 2719-2733
-
-
Massie, C.E.1
Lynch, A.2
Ramos-Montoya, A.3
Boren, J.4
Stark, R.5
Fazli, L.6
-
39
-
-
33747880070
-
Androgens induce prostate cancer cell proliferation through mammalian target of rapamycin activation and post-transcriptional increases in cyclin D proteins
-
DOI 10.1158/0008-5472.CAN-05-4472
-
Xu Y, Chen SY, Ross KN, Balk SP. Androgens induce prostate cancer cell proliferation through mammalian target of rapamycin activation and post-tran-scriptional increases in cyclin D proteins. Cancer Res 2006; 66: 7783-7792. (Pubitemid 44289239)
-
(2006)
Cancer Research
, vol.66
, Issue.15
, pp. 7783-7792
-
-
Xu, Y.1
Chen, S.-Y.2
Ross, K.N.3
Balk, S.P.4
-
40
-
-
0032493489
-
1 regulatory elements control the androgen-dependent proliferation of prostatic carcinoma cells
-
DOI 10.1074/jbc.273.32.20213
-
Knudsen KE, Arden KC, Cavenee WK. Multiple G1 regulatory elements control the androgen-dependent proliferation of prostatic carcinoma cells. J Biol Chem 1998; 273: 20213-20222. (Pubitemid 28377582)
-
(1998)
Journal of Biological Chemistry
, vol.273
, Issue.32
, pp. 20213-20222
-
-
Knudsen, K.E.1
Arden, K.C.2
Cavenee, W.K.3
-
42
-
-
2342500360
-
The F-box protein SKP2 mediates androgen control of p27 stability in LNCaP human prostate cancer cells
-
Lu L, Schulz H, Wolf DA. The F-box protein SKP2 mediates androgen control of p27 stability in LNCaP human prostate cancer cells. BMC Cell Biol 2002; 3: 22.
-
(2002)
BMC Cell Biol
, vol.3
, pp. 22
-
-
Lu, L.1
Schulz, H.2
Wolf, D.A.3
-
43
-
-
84862926298
-
Androgen receptor enhances p27 degradation in prostate cancer cells through rapid and selective TORC2 activation
-
Fang Z, Zhang T, Dizeyi N, Chen S, Wang H, Swanson KD et al. Androgen receptor enhances p27 degradation in prostate cancer cells through rapid and selective TORC2 activation. J Biol Chem 2012; 287: 2090-2098.
-
(2012)
J Biol Chem
, vol.287
, pp. 2090-2098
-
-
Fang, Z.1
Zhang, T.2
Dizeyi, N.3
Chen, S.4
Wang, H.5
Swanson, K.D.6
-
44
-
-
84864256852
-
Doxycycline regulated induction of AKT in murine prosate drives proliferation independently of p27 cyclin dependent kinase inhibitor downregulation
-
Wang H, Xu Y, Fang Z, Chen S, Balk SP, Yuan X. Doxycycline regulated induction of AKT in murine prosate drives proliferation independently of p27 cyclin dependent kinase inhibitor downregulation. PLoS ONE 2012; 7: e41330.
-
(2012)
PLoS ONE
, vol.7
-
-
Wang, H.1
Xu, Y.2
Fang, Z.3
Chen, S.4
Balk, S.P.5
Yuan, X.6
-
45
-
-
0032913866
-
Androgen regulation of the cyclin-dependent kinase inhibitor p21 gene through an androgen response element in the proximal promoter
-
Lu S, Liu M, Epner DE, Tsai SY, Tsai MJ. Androgen regulation of the cyclin-dependent kinase inhibitor p21 gene through an androgen response element in the proximal promoter. Mol Endocrinol 1999; 13: 376-384. (Pubitemid 29113870)
-
(1999)
Molecular Endocrinology
, vol.13
, Issue.3
, pp. 376-384
-
-
Lu, S.1
Liu, M.2
Epner, D.E.3
Tsai, S.Y.4
Tsai, M.-J.5
-
46
-
-
0027053785
-
Heparin-binding keratinocyte growth factor is a candidate stromal to epithelial cell andromedin
-
DOI 10.1210/me.6.12.2123
-
Yan G, Fukabori Y, Nikolaropoulos S, Wang F, McKeehan WL. Heparin-binding keratinocyte growth factor is a candidate stromal-to-epithelial-cell andromedin. Mol Endocrinol 1992; 6: 2123-2128. (Pubitemid 23021561)
-
(1992)
Molecular Endocrinology
, vol.6
, Issue.12
, pp. 2123-2128
-
-
Yan, G.1
Fukabori, Y.2
Nikolaropoulos, S.3
Wang, F.4
McKeehan, W.L.5
-
47
-
-
0034749483
-
Androgen suppression of GnRH-stimulated rat LHβ gene transcription occurs through Sp1 sites in the distal GnRH-responsive promoter region
-
DOI 10.1210/me.15.11.1906
-
Curtin D, Jenkins S, Farmer N, Anderson AC, Haisenleder DJ, Rissman E et al. Androgen suppression of GnRH-stimulated rat LHbeta gene transcription occurs through Sp1 sites in the distal GnRH-responsive promoter region. Mol Endocrinol 2001; 15: 1906-1917. (Pubitemid 33022531)
-
(2001)
Molecular Endocrinology
, vol.15
, Issue.11
, pp. 1906-1917
-
-
Curtin, D.1
Jenkins, S.2
Farmer, N.3
Anderson, A.C.4
Haisenleder, D.J.5
Rissman, E.6
Wilson, E.M.7
Shupnik, M.A.8
-
48
-
-
33847057016
-
The androgen receptor negatively regulates the expression of c-Met: Implications for a novel mechanism of prostate cancer progression
-
Verras M, Lee J, Xue H, Li TH, Wang Y, Sun Z. The androgen receptor negatively regulates the expression of c-Met: implications for a novel mechanism of prostate cancer progression. Cancer Res 2007; 67: 967-975.
-
(2007)
Cancer Res
, vol.67
, pp. 967-975
-
-
Verras, M.1
Lee, J.2
Xue, H.3
Li, T.H.4
Wang, Y.5
Sun, Z.6
-
50
-
-
0034283030
-
Beta-catenin affects androgen receptor tran-scriptional activity and ligand specificity
-
Truica CI, Byers S, Gelmann EP. Beta-catenin affects androgen receptor tran-scriptional activity and ligand specificity. Cancer Res 2000; 60: 4709-4713.
-
(2000)
Cancer Res
, vol.60
, pp. 4709-4713
-
-
Truica, C.I.1
Byers, S.2
Gelmann, E.P.3
-
51
-
-
0347481364
-
Trans-repression of β-Catenin Activity by Nuclear Receptors
-
DOI 10.1074/jbc.M307154200
-
Shah S, Hecht A, Pestell R, Byers SW. Trans-repression of beta-catenin activity by nuclear receptors. J Biol Chem 2003; 278: 48137-48145. (Pubitemid 37523266)
-
(2003)
Journal of Biological Chemistry
, vol.278
, Issue.48
, pp. 48137-48145
-
-
Shah, S.1
Hecht, A.2
Pestell, R.3
Byers, S.W.4
-
52
-
-
0037192870
-
Linking beta-catenin to androgen-signaling pathway
-
Yang F, Li X, Sharma M, Sasaki CY, Longo DL, Lim B et al. Linking beta-catenin to androgen-signaling pathway. J Biol Chem 2002; 277: 11336-11344.
-
(2002)
J Biol Chem
, vol.277
, pp. 11336-11344
-
-
Yang, F.1
Li, X.2
Sharma, M.3
Sasaki, C.Y.4
Longo, D.L.5
Lim, B.6
-
53
-
-
0037028210
-
Ligand-dependent inhibition of β-catenin/TCF signaling by androgen receptor
-
DOI 10.1038/sj.onc.1206049
-
Chesire DR, Isaacs WB. Ligand-dependent inhibition of beta-catenin/TCF signaling by androgen receptor. Oncogene 2002; 21: 8453-8469. (Pubitemid 36054886)
-
(2002)
Oncogene
, vol.21
, Issue.55
, pp. 8453-8469
-
-
Chesire, D.R.1
Isaacs, W.B.2
-
54
-
-
0041335563
-
Functional localization and competition between the androgen receptor and T-cell factor for nuclear β-catenin: A means for inhibition of the Tcf signaling axis
-
DOI 10.1038/sj.onc.1206802
-
Mulholland DJ, Read JT, Rennie PS, Cox ME, Nelson CC. Functional localization and competition between the androgen receptor and T-cell factor for nuclear beta-catenin: a means for inhibition of the Tcf signaling axis. Oncogene 2003; 22: 5602-5613. (Pubitemid 37102696)
-
(2003)
Oncogene
, vol.22
, Issue.36
, pp. 5602-5613
-
-
Mulholland, D.J.1
Read, J.T.2
Rennie, P.S.3
Cox, M.E.4
Nelson, C.C.5
-
55
-
-
31344433667
-
Activation of β-catenin signaling in prostate cancer by peptidyl-prolyl isomerase pin1-mediated abrogation of the androgen receptor-β-catenin interaction
-
DOI 10.1128/MCB.26.3.929-939.2006
-
Chen SY, Wulf G, Zhou XZ, Rubin MA, Lu KP, Balk SP. Activation of beta-catenin signaling in prostate cancer by peptidyl-prolyl isomerase Pin1-mediated abrogation of the androgen receptor-beta-catenin interaction. Mol Cell Biol 2006; 26: 929-939. (Pubitemid 43146487)
-
(2006)
Molecular and Cellular Biology
, vol.26
, Issue.3
, pp. 929-939
-
-
Chen, S.-Y.1
Wulf, G.2
Zhou, X.Z.3
Rubin, M.A.4
Lu, K.P.5
Balk, S.P.6
-
56
-
-
0035824617
-
SRY interacts with and negatively regulates androgen receptor transcriptional activity
-
Yuan X, Lu ML, Li T, Balk SP. SRY interacts with and negatively regulates androgen receptor transcriptional activity. J Biol Chem 2001; 276: 46647-46654.
-
(2001)
J Biol Chem
, vol.276
, pp. 46647-46654
-
-
Yuan, X.1
Lu, M.L.2
Li, T.3
Balk, S.P.4
-
57
-
-
36248949022
-
Interaction between the androgen receptor and a segment of its corepressor SHP
-
DOI 10.1107/S0907444907045702, PII S0907444907045702
-
Jouravel N, Sablin E, Arnold LA, Guy RK, Fletterick RJ. Interaction between the androgen receptor and a segment of its corepressor SHP. Acta Crystallogr D Biol Crystallogr 2007; 63: 1198-1200. (Pubitemid 350134954)
-
(2007)
Acta Crystallographica Section D: Biological Crystallography
, vol.63
, Issue.11
, pp. 1198-1200
-
-
Jouravel, N.1
Sablin, E.2
Arnold, L.A.3
Guy, R.K.4
Fletterick, R.J.5
-
58
-
-
34250800192
-
Alien interacts with the human androgen receptor and inhibits prostate cancer cell growth
-
DOI 10.1210/me.2006-0468
-
Moehren U, Papaioannou M, Reeb CA, Hong W, Baniahmad A. Alien interacts with the human androgen receptor and inhibits prostate cancer cell growth. Mol Endocrinol 2007; 21: 1039-1048. (Pubitemid 46984757)
-
(2007)
Molecular Endocrinology
, vol.21
, Issue.5
, pp. 1039-1048
-
-
Moehren, U.1
Papaioannou, M.2
Reeb, C.A.3
Hong, W.4
Baniahmad, A.5
-
59
-
-
33947244442
-
Prohibitin, a protein downregulated by androgens, represses androgen receptor activity
-
DOI 10.1038/sj.onc.1209967, PII 1209967
-
Gamble SC, Chotai D, Odontiadis M, Dart DA, Brooke GN, Powell SM et al. Prohibitin, a protein downregulated by androgens, represses androgen receptor activity. Oncogene 2007; 26: 1757-1768. (Pubitemid 46426196)
-
(2007)
Oncogene
, vol.26
, Issue.12
, pp. 1757-1768
-
-
Gamble, S.C.1
Chotai, D.2
Odontiadis, M.3
Dart, D.A.4
Brooke, G.N.5
Powell, S.M.6
Reebye, V.7
Varela-Carver, A.8
Kawano, Y.9
Waxman, J.10
Bevan, C.L.11
-
60
-
-
13444282183
-
Hey1, a mediator of Notch signaling, is an androgen receptor corepressor
-
DOI 10.1128/MCB.25.4.1425-1436.2005
-
Belandia B, Powell SM, Garcia-Pedrero JM, Walker MM, Bevan CL, Parker MG. Hey1, a mediator of notch signaling, is an androgen receptor corepressor. Mol Cell Biol 2005; 25: 1425-1436. (Pubitemid 40204919)
-
(2005)
Molecular and Cellular Biology
, vol.25
, Issue.4
, pp. 1425-1436
-
-
Belandia, B.1
Powell, S.M.2
Garcia-Pedrero, J.M.3
Walker, M.M.4
Bevan, C.L.5
Parker, M.G.6
-
61
-
-
0034948672
-
Inhibition of androgen receptor-mediated transcription by amino-terminal enhancer of split
-
DOI 10.1128/MCB.21.14.4614-4625.2001
-
Yu X, Li P, Roeder RG, Wang Z. Inhibition of androgen receptor-mediated transcription by amino-terminal enhancer of split. Mol Cell Biol 2001; 21: 4614-4625. (Pubitemid 32588244)
-
(2001)
Molecular and Cellular Biology
, vol.21
, Issue.14
, pp. 4614-4625
-
-
Yu, X.1
Li, P.2
Roeder, R.G.3
Wang, Z.4
-
62
-
-
33746507785
-
The corepressors silencing mediator of retinoid and thyroid hormone receptor and nuclear receptor corepressor are involved in agonist-and antagonist-regulated transcription by androgen receptor
-
Yoon HG, Wong J. The corepressors silencing mediator of retinoid and thyroid hormone receptor and nuclear receptor corepressor are involved in agonist-and antagonist-regulated transcription by androgen receptor. Mol Endocrinol 2006; 20: 1048-1060.
-
(2006)
Mol Endocrinol
, vol.20
, pp. 1048-1060
-
-
Yoon, H.G.1
Wong, J.2
-
63
-
-
85047683640
-
Inhibition of the dihydrotestosterone-activated androgen receptor by nuclear receptor corepressor
-
DOI 10.1210/me.16.7.1492
-
Cheng S, Brzostek S, Lee SR, Hollenberg AN, Balk SP. Inhibition of the dihy-drotestosterone-activated androgen receptor by nuclear receptor corepressor. Mol Endocrinol 2002; 16: 1492-1501. (Pubitemid 34743669)
-
(2002)
Molecular Endocrinology
, vol.16
, Issue.7
, pp. 1492-1501
-
-
Cheng, S.1
Brzostek, S.2
Lee, S.R.3
Hollenberg, A.N.4
Balk, S.P.5
-
64
-
-
14844288915
-
The androgen receptor recruits nuclear receptor corepressor (N-CoR) in the presence of mifepristone via its N and C termini revealing a novel molecular mechanism for androgen receptor antagonists
-
DOI 10.1074/jbc.M408972200
-
Hodgson MC, Astapova I, Cheng S, Lee LJ, Verhoeven MC, Choi E et al. The androgen receptor recruits nuclear receptor CoRepressor (N-CoR) in the presence of mifepristone via its N and C termini revealing a novel molecular mechanism for androgen receptor antagonists. J Biol Chem 2005; 280: 6511-6519. (Pubitemid 40341200)
-
(2005)
Journal of Biological Chemistry
, vol.280
, Issue.8
, pp. 6511-6519
-
-
Hodgson, M.C.1
Astapova, I.2
Cheng, S.3
Lee, L.J.4
Verhoeven, M.C.5
Choi, E.6
Balk, S.P.7
Hollenberg, A.N.8
-
65
-
-
0346025352
-
Antiandrogen Effects of Mifepristone on Coactivator and Corepressor Interactions with the Androgen Receptor
-
DOI 10.1210/me.2003-0189
-
Song LN, Coghlan M, Gelmann EP. Antiandrogen effects of mifepristone on coactivator and corepressor interactions with the androgen receptor. Mol Endocrinol 2004; 18: 70-85. (Pubitemid 38073155)
-
(2004)
Molecular Endocrinology
, vol.18
, Issue.1
, pp. 70-85
-
-
Song, L.-N.1
Coghlan, M.2
Gelmann, E.P.3
-
66
-
-
84863041971
-
Cooperation between Polycomb and androgen receptor during oncogenic transformation
-
Zhao JC, Yu J, Runkle C, Wu L, Hu M, Wu D et al. Cooperation between Polycomb and androgen receptor during oncogenic transformation. Genome Res 2012; 22: 322-331.
-
(2012)
Genome Res
, vol.22
, pp. 322-331
-
-
Zhao, J.C.1
Yu, J.2
Runkle, C.3
Wu, L.4
Hu, M.5
Wu, D.6
-
67
-
-
84862161257
-
A transcriptional repressor co-regulatory network governing androgen response in prostate cancers
-
Chng KR, Chang CW, Tan SK, Yang C, Hong SZ, Sng NY et al. A transcriptional repressor co-regulatory network governing androgen response in prostate cancers. EMBO J 2012; 31: 2810-2823.
-
(2012)
EMBO J
, vol.31
, pp. 2810-2823
-
-
Chng, K.R.1
Chang, C.W.2
Tan, S.K.3
Yang, C.4
Hong, S.Z.5
Sng, N.Y.6
-
68
-
-
24144462170
-
LSD1 demethylates repressive histone marks to promote androgen-receptor- dependent transcription
-
DOI 10.1038/nature04020, PII N04020
-
Metzger E, Wissmann M, Yin N, Muller JM, Schneider R, Peters AH et al. LSD1 demethylates repressive histone marks to promote androgen-receptor-depen- dent transcription. Nature 2005; 437: 436-439. (Pubitemid 41613508)
-
(2005)
Nature
, vol.437
, Issue.7057
, pp. 436-439
-
-
Metzger, E.1
Wissmann, M.2
Yin, N.3
Muller, J.M.4
Schneider, R.5
Peters, A.H.F.M.6
Gunther, T.7
Buettner, R.8
Schule, R.9
-
69
-
-
33847392500
-
Cooperative demethylation by JMJD2C and LSD1 promotes androgen receptor-dependent gene expression
-
Wissmann M, Yin N, Muller JM, Greschik H, Fodor BD, Jenuwein T et al. Cooperative demethylation by JMJD2C and LSD1 promotes androgen receptor-dependent gene expression. Nat Cell Biol 2007; 9: 347-353.
-
(2007)
Nat Cell Biol
, vol.9
, pp. 347-353
-
-
Wissmann, M.1
Yin, N.2
Muller, J.M.3
Greschik, H.4
Fodor, B.D.5
Jenuwein, T.6
-
70
-
-
80054761058
-
Androgen receptor gene expression in prostate cancer is directly suppressed by the androgen receptor through recruitment of lysine-specific demethylase 1
-
Cai C, He HH, Chen S, Coleman I, Wang H, Fang Z et al. Androgen receptor gene expression in prostate cancer is directly suppressed by the androgen receptor through recruitment of lysine-specific demethylase 1. Cancer Cell 2011; 20: 457-471.
-
(2011)
Cancer Cell
, vol.20
, pp. 457-471
-
-
Cai, C.1
He, H.H.2
Chen, S.3
Coleman, I.4
Wang, H.5
Fang, Z.6
-
71
-
-
11144332565
-
Histone demethylation mediated by the nuclear amine oxidase homolog LSD1
-
DOI 10.1016/j.cell.2004.12.012, PII S0092867404011997
-
Shi Y, Lan F, Matson C, Mulligan P, Whetstine JR, Cole PA et al. Histone deme-thylation mediated by the nuclear amine oxidase homolog LSD1. Cell 2004; 119: 941-953. (Pubitemid 40037608)
-
(2004)
Cell
, vol.119
, Issue.7
, pp. 941-953
-
-
Shi, Y.1
Lan, F.2
Matson, C.3
Mulligan, P.4
Whetstine, J.R.5
Cole, P.A.6
Casero, R.A.7
Shi, Y.8
-
72
-
-
33846690407
-
Histone Methylation-Dependent Mechanisms Impose Ligand Dependency for Gene Activation by Nuclear Receptors
-
DOI 10.1016/j.cell.2006.12.038, PII S0092867407000621
-
Garcia-Bassets I, Kwon YS, Telese F, Prefontaine GG, Hutt KR, Cheng CS et al. Histone methylation-dependent mechanisms impose ligand dependency for gene activation by nuclear receptors. Cell 2007; 128: 505-518. (Pubitemid 46198894)
-
(2007)
Cell
, vol.128
, Issue.3
, pp. 505-518
-
-
Garcia-Bassets, I.1
Kwon, Y.-S.2
Telese, F.3
Prefontaine, G.G.4
Hutt, K.R.5
Cheng, C.S.6
Ju, B.-G.7
Ohgi, K.A.8
Wang, J.9
Escoubet-Lozach, L.10
Rose, DavidW.11
Glass, C.K.12
Fu, X.-D.13
Rosenfeld, M.G.14
-
73
-
-
58049208232
-
Enhancing nuclear receptor-induced transcription requires nuclear motor and LSD1-dependent gene networking in interchromatin granules
-
Hu Q, Kwon YS, Nunez E, Cardamone MD, Hutt KR, Ohgi KA et al. Enhancing nuclear receptor-induced transcription requires nuclear motor and LSD1-dependent gene networking in interchromatin granules. Proc Natl Acad Sci USA 2008; 105: 19199-19204.
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, pp. 19199-19204
-
-
Hu, Q.1
Kwon, Y.S.2
Nunez, E.3
Cardamone, M.D.4
Hutt, K.R.5
Ohgi, K.A.6
-
74
-
-
38149045693
-
DNA oxidation as triggered by H3K9me2 demethylation drives estrogen-induced gene expression
-
Perillo B, Ombra MN, Bertoni A, Cuozzo C, Sacchetti S, Sasso A et al. DNA oxidation as triggered by H3K9me2 demethylation drives estrogen-induced gene expression. Science 2008; 319: 202-206.
-
(2008)
Science
, vol.319
, pp. 202-206
-
-
Perillo, B.1
Ombra, M.N.2
Bertoni, A.3
Cuozzo, C.4
Sacchetti, S.5
Sasso, A.6
-
75
-
-
34247348215
-
Opposing LSD1 complexes function in developmental gene activation and repression programmes
-
DOI 10.1038/nature05671, PII NATURE05671
-
Wang J, Scully K, Zhu X, Cai L, Zhang J, Prefontaine GG et al. Opposing LSD1 complexes function in developmental gene activation and repression programmes. Nature 2007; 446: 882-887. (Pubitemid 46633160)
-
(2007)
Nature
, vol.446
, Issue.7138
, pp. 882-887
-
-
Wang, J.1
Scully, K.2
Zhu, X.3
Cai, L.4
Zhang, J.5
Prefontaine, G.G.6
Krones, A.7
Ohgi, K.A.8
Zhu, P.9
Garcia-Bassets, I.10
Liu, F.11
Taylor, H.12
Lozach, J.13
Jayes, F.L.14
Korach, K.S.15
Glass, C.K.16
Fu, X.-D.17
Rosenfeld, M.G.18
-
76
-
-
37749026136
-
Phosphorylation of histone H3 at threonine 11 establishes a novel chromatin mark for transcriptional regulation
-
Metzger E, Yin N, Wissmann M, Kunowska N, Fischer K, Friedrichs N et al. Phosphorylation of histone H3 at threonine 11 establishes a novel chromatin mark for transcriptional regulation. Nat Cell Biol 2008; 10: 53-60.
-
(2008)
Nat Cell Biol
, vol.10
, pp. 53-60
-
-
Metzger, E.1
Yin, N.2
Wissmann, M.3
Kunowska, N.4
Fischer, K.5
Friedrichs, N.6
-
77
-
-
77950460256
-
Phosphor-ylation of histone H3T6 by PKCbeta(I) controls demethylation at histone H3K4
-
Metzger E, Imhof A, Patel D, Kahl P, Hoffmeyer K, Friedrichs N et al. Phosphor-ylation of histone H3T6 by PKCbeta(I) controls demethylation at histone H3K4. Nature 2010; 464: 792-796.
-
(2010)
Nature
, vol.464
, pp. 792-796
-
-
Metzger, E.1
Imhof, A.2
Patel, D.3
Kahl, P.4
Hoffmeyer, K.5
Friedrichs, N.6
-
78
-
-
80054021222
-
Intratumoral de novo steroid synthesis activates androgen receptor in castration-resistant prostate cancer and is upregulated by treatment with CYP17A1 inhibitors
-
Cai C, Chen S, Ng P, Bubley GJ, Nelson PS, Mostaghel EA et al. Intratumoral de novo steroid synthesis activates androgen receptor in castration-resistant prostate cancer and is upregulated by treatment with CYP17A1 inhibitors. Cancer Res 2011; 71: 6503-6513.
-
(2011)
Cancer Res
, vol.71
, pp. 6503-6513
-
-
Cai, C.1
Chen, S.2
Ng, P.3
Bubley, G.J.4
Nelson, P.S.5
Mostaghel, E.A.6
-
79
-
-
65349089474
-
Genomic strategy for targeting therapy in castration-resistant prostate cancer
-
Mendiratta P, Mostaghel E, Guinney J, Tewari AK, Porrello A, Barry WT et al. Genomic strategy for targeting therapy in castration-resistant prostate cancer. J Clin Oncol 2009; 27: 2022-2029.
-
(2009)
J Clin Oncol
, vol.27
, pp. 2022-2029
-
-
Mendiratta, P.1
Mostaghel, E.2
Guinney, J.3
Tewari, A.K.4
Porrello, A.5
Barry, W.T.6
-
80
-
-
27344451557
-
Recurrent fusion of TMPRSS2 and ETS transcription factor genes in prostate cancer
-
DOI 10.1126/science.1117679
-
Tomlins SA, Rhodes DR, Perner S, Dhanasekaran SM, Mehra R, Sun XW et al. Recurrent fusion of TMPRSS2 and ETS transcription factor genes in prostate cancer. Science 2005; 310: 644-648. (Pubitemid 41528150)
-
(2005)
Science
, vol.310
, Issue.5748
, pp. 644-648
-
-
Tomlins, S.A.1
Rhodes, D.R.2
Perner, S.3
Dhanasekaran, S.M.4
Mehra, R.5
Sun, X.-W.6
Varambally, S.7
Cao, X.8
Tchinda, J.9
Kuefer, R.10
Lee, C.11
Montie, J.E.12
Shah, R.B.13
Pienta, K.J.14
Rubin, M.A.15
Chinnaiyan, A.M.16
-
81
-
-
39049150843
-
Role of the TMPRSS2-ERG gene fusion in prostate cancer
-
DOI 10.1593/neo.07822
-
Tomlins SA, Laxman B, Varambally S, Cao X, Yu J, Helgeson BE et al. Role of the TMPRSS2-ERG gene fusion in prostate cancer. Neoplasia 2008; 10: 177-188. (Pubitemid 351240884)
-
(2008)
Neoplasia
, vol.10
, Issue.2
, pp. 177-188
-
-
Tomlins, S.A.1
Laxman, B.2
Varambally, S.3
Cao, X.4
Yu, J.5
Helgeson, B.E.6
Cao, Q.7
Prensner, J.R.8
Rubin, M.A.9
Shah, R.B.10
Mehra, R.11
Chinnaiyan, A.M.12
-
82
-
-
77952103123
-
An integrated network of androgen receptor, polycomb, and TMPRSS2-ERG gene fusions in prostate cancer progression
-
Yu J, Mani RS, Cao Q, Brenner CJ, Cao X, Wang X et al. An integrated network of androgen receptor, polycomb, and TMPRSS2-ERG gene fusions in prostate cancer progression. Cancer Cell 2010; 17: 443-454.
-
(2010)
Cancer Cell
, vol.17
, pp. 443-454
-
-
Yu, J.1
Mani, R.S.2
Cao, Q.3
Brenner, C.J.4
Cao, X.5
Wang, X.6
-
83
-
-
84868612058
-
Sox9 is required for prostate development and prostate cancer initiation
-
Huang Z, Hurley PJ, Simons BW, Marchionni L, Berman DM, Ross AE et al. Sox9 is required for prostate development and prostate cancer initiation. Oncotarget 2012; 3: 651-663.
-
(2012)
Oncotarget
, vol.3
, pp. 651-663
-
-
Huang, Z.1
Hurley, P.J.2
Simons, B.W.3
Marchionni, L.4
Berman, D.M.5
Ross, A.E.6
-
84
-
-
57349137675
-
Androgen-induced programs for prostate epithelial growth and invasion arise in embryogenesis and are reactivated in cancer
-
Schaeffer EM, Marchionni L, Huang Z, Simons B, Blackman A, Yu W et al. Androgen-induced programs for prostate epithelial growth and invasion arise in embryogenesis and are reactivated in cancer. Oncogene 2008; 27: 7180-7191.
-
(2008)
Oncogene
, vol.27
, pp. 7180-7191
-
-
Schaeffer, E.M.1
Marchionni, L.2
Huang, Z.3
Simons, B.4
Blackman, A.5
Yu, W.6
-
86
-
-
40949145618
-
SOX9 is expressed in human fetal prostate epithelium and enhances prostate cancer invasion
-
DOI 10.1158/0008-5472.CAN-07-5915
-
Wang H, Leav I, Ibaragi S, Wegner M, Hu GF, Lu ML et al. SOX9 is expressed in human fetal prostate epithelium and enhances prostate cancer invasion. Cancer Res 2008; 68: 1625-1630. (Pubitemid 351416545)
-
(2008)
Cancer Research
, vol.68
, Issue.6
, pp. 1625-1630
-
-
Wang, H.1
Leav, I.2
Ibaragi, S.3
Wegner, M.4
Hu, G.-F.5
Lu, M.L.6
Balk, S.P.7
Yuan, X.8
-
87
-
-
84874598190
-
ERG induces androgen receptor-mediated regulation of SOX9 in prostate cancer
-
Cai C, Wang H, He HH, Chen S, He L, Ma F et al. ERG induces androgen receptor-mediated regulation of SOX9 in prostate cancer. J Clin Invest 2013; 123: 1109-1122.
-
(2013)
J Clin Invest
, vol.123
, pp. 1109-1122
-
-
Cai, C.1
Wang, H.2
He, H.H.3
Chen, S.4
He, L.5
Ma, F.6
-
88
-
-
76249098305
-
SOX9 elevation in the prostate promotes proliferation and cooperates with PTEN loss to drive tumor formation
-
Thomsen MK, Ambroisine L, Wynn S, Cheah KS, Foster CS, Fisher G et al. SOX9 elevation in the prostate promotes proliferation and cooperates with PTEN loss to drive tumor formation. Cancer Res 2010; 70: 979-987.
-
(2010)
Cancer Res
, vol.70
, pp. 979-987
-
-
Thomsen, M.K.1
Ambroisine, L.2
Wynn, S.3
Cheah, K.S.4
Foster, C.S.5
Fisher, G.6
-
89
-
-
36649025928
-
Inducible FGFR-1 Activation Leads to Irreversible Prostate Adenocarcinoma and an Epithelial-to-Mesenchymal Transition
-
DOI 10.1016/j.ccr.2007.11.004, PII S1535610807003352
-
Acevedo VD, Gangula RD, Freeman KW, Li R, Zhang Y, Wang F et al. Inducible FGFR-1 activation leads to irreversible prostate adenocarcinoma and an epithelial-to-mesenchymal transition. Cancer Cell 2007; 12: 559-571. (Pubitemid 350199071)
-
(2007)
Cancer Cell
, vol.12
, Issue.6
, pp. 559-571
-
-
Acevedo, V.D.1
Gangula, R.D.2
Freeman, K.W.3
Li, R.4
Zhang, Y.5
Wang, F.6
Ayala, G.E.7
Peterson, L.E.8
Ittmann, M.9
Spencer, D.M.10
-
90
-
-
33846673020
-
SOX9 is expressed in normal prostate basal cells and regulates androgen receptor expression in prostate cancer cells
-
DOI 10.1158/0008-5472.CAN-06-1672
-
Wang H, McKnight NC, Zhang T, Lu ML, Balk SP, Yuan X. SOX9 is expressed in normal prostate basal cells and regulates androgen receptor expression in prostate cancer cells. Cancer Res 2007; 67: 528-536. (Pubitemid 46192189)
-
(2007)
Cancer Research
, vol.67
, Issue.2
, pp. 528-536
-
-
Wang, H.1
McKnight, N.C.2
Zhang, T.3
Lu, M.L.4
Balk, S.P.5
Yuan, X.6
-
91
-
-
79955068168
-
Possible risk factors associated with relpase in patients treated with neoadjuvant chemo-hormonal therapy for high risk prostate cancer
-
Bhatt RS, Werner L, Regan MM, Yannucci J, Ko Y-J, Wang H-Y et al. Possible risk factors associated with relpase in patients treated with neoadjuvant chemo-hormonal therapy for high risk prostate cancer. Open Prostate Cancer J 2011; 4: 1-8.
-
(2011)
Open Prostate Cancer J
, vol.4
, pp. 1-8
-
-
Bhatt, R.S.1
Werner, L.2
Regan, M.M.3
Yannucci, J.4
Ko, Y.-J.5
Wang, H.-Y.6
-
92
-
-
33845884027
-
Integrative molecular concept modeling of prostate cancer progression
-
DOI 10.1038/ng1935, PII NG1935
-
Tomlins SA, Mehra R, Rhodes DR, Cao X, Wang L, Dhanasekaran SM et al. Inte-grative molecular concept modeling of prostate cancer progression. Nat Genet 2007; 39: 41-51. (Pubitemid 46026500)
-
(2007)
Nature Genetics
, vol.39
, Issue.1
, pp. 41-51
-
-
Tomlins, S.A.1
Mehra, R.2
Rhodes, D.R.3
Cao, X.4
Wang, L.5
Dhanasekaran, S.M.6
Kalyana-Sundaram, S.7
Wei, J.T.8
Rubin, M.A.9
Pienta, K.J.10
Shah, R.B.11
Chinnaiyan, A.M.12
-
93
-
-
84871052080
-
EZH2 oncogenic activity in castration-resistant prostate cancer cells is Polycomb-independent
-
Xu K, Wu ZJ, Groner AC, He HH, Cai C, Lis RT et al. EZH2 oncogenic activity in castration-resistant prostate cancer cells is Polycomb-independent. Science 2012; 338: 1465-1469.
-
(2012)
Science
, vol.338
, pp. 1465-1469
-
-
Xu, K.1
Wu, Z.J.2
Groner, A.C.3
He, H.H.4
Cai, C.5
Lis, R.T.6
-
94
-
-
84863979005
-
Distinct transcriptional programs mediated by the ligand-dependent full-length androgen receptor and its splice variants in castration-resistant prostate cancer
-
Hu R, Lu C, Mostaghel EA, Yegnasubramanian S, Gurel M, Tannahill C et al. Distinct transcriptional programs mediated by the ligand-dependent full-length androgen receptor and its splice variants in castration-resistant prostate cancer. Cancer Res 2012; 72: 3457-3462.
-
(2012)
Cancer Res
, vol.72
, pp. 3457-3462
-
-
Hu, R.1
Lu, C.2
Mostaghel, E.A.3
Yegnasubramanian, S.4
Gurel, M.5
Tannahill, C.6
-
95
-
-
84861728843
-
Androgen receptor splice variants activate androgen receptor target genes and support aberrant prostate cancer cell growth independent of canonical androgen receptor nuclear localization signal
-
Chan SC, Li Y, Dehm SM. Androgen receptor splice variants activate androgen receptor target genes and support aberrant prostate cancer cell growth independent of canonical androgen receptor nuclear localization signal. J Biol Chem 2012; 287: 19736-19749.
-
(2012)
J Biol Chem
, vol.287
, pp. 19736-19749
-
-
Chan, S.C.1
Li, Y.2
Dehm, S.M.3
-
96
-
-
84872534568
-
Androgen receptor splice variants mediate enzalutamide resistance in castration-resistant prostate cancer cell lines
-
Li Y, Chan SC, Brand LJ, Hwang TH, Silverstein KA, Dehm SM. Androgen receptor splice variants mediate enzalutamide resistance in castration-resistant prostate cancer cell lines. Cancer Res 2013; 73: 483-489.
-
(2013)
Cancer Res
, vol.73
, pp. 483-489
-
-
Li, Y.1
Chan, S.C.2
Brand, L.J.3
Hwang, T.H.4
Silverstein, K.A.5
Dehm, S.M.6
-
97
-
-
0023245164
-
Effects of castration compared with total androgen blockade on tissue dihydrotestosterone (DHT) concentration in benign prostatic hyperplasia (BPH)
-
Geller J, Albert J. Effects of castration compared with total androgen blockade on tissue dihydrotestosterone (DHT) concentration in benign prostatic hyperplasia (BPH). Urol Res 1987; 15: 151-153. (Pubitemid 17116900)
-
(1987)
Urological Research
, vol.15
, Issue.3
, pp. 151-153
-
-
Geller, J.1
Albert, J.2
-
98
-
-
0024318399
-
Comparison of residual C-19 steroids in plasma and prostatic tissue of human, rat and guinea pig after castration: Unique importance of extratesticular androgens in men
-
DOI 10.1016/0022-4731(89)90514-1
-
Belanger B, Belanger A, Labrie F, Dupont A, Cusan L, Monfette G. Comparison of residual C-19 steroids in plasma and prostatic tissue of human, rat and guinea pig after castration: unique importance of extratesticular androgens in men. J Steroid Biochem 1989; 32: 695-698. (Pubitemid 19176012)
-
(1989)
Journal of Steroid Biochemistry
, vol.32
, Issue.5
, pp. 695-698
-
-
Belanger, B.1
Belanger, A.2
Labrie, F.3
Dupont, A.4
Cusan, L.5
Monfette, G.6
-
99
-
-
1642475101
-
The Adrenal Androgen Androstenediol Is Present in Prostate Cancer Tissue after Androgen Deprivation Therapy and Activates Mutated Androgen Receptor
-
DOI 10.1158/0008-5472.CAN-03-0130
-
Mizokami A, Koh E, Fujita H, Maeda Y, Egawa M, Koshida K et al. The adrenal androgen androstenediol is present in prostate cancer tissue after androgen deprivation therapy and activates mutated androgen receptor. Cancer Res 2004; 64: 765-771. (Pubitemid 38120921)
-
(2004)
Cancer Research
, vol.64
, Issue.2
, pp. 765-771
-
-
Mizokami, A.1
Koh, E.2
Fujita, H.3
Maeda, Y.4
Egawa, M.5
Koshida, K.6
Honma, S.7
Keller, E.T.8
Namiki, M.9
-
100
-
-
8444231965
-
The influence of androgen deprivation therapy on dihydrotestosterone levels in the prostatic tissue of patients with prostate cancer
-
DOI 10.1158/1078-0432.CCR-04-0913
-
Nishiyama T, Hashimoto Y, Takahashi K. The influence of androgen deprivation therapy on dihydrotestosterone levels in the prostatic tissue of patients with prostate cancer. Clin Cancer Res 2004; 10: 7121-7126. (Pubitemid 39487695)
-
(2004)
Clinical Cancer Research
, vol.10
, Issue.21
, pp. 7121-7126
-
-
Nishiyama, T.1
Hashimoto, Y.2
Takahashi, K.3
-
101
-
-
33749550602
-
Persistent intraprostatic androgen concentrations after medical castration in healthy men
-
DOI 10.1210/jc.2006-0968
-
Page ST, Lin DW, Mostaghel EA, Hess DL, True LD, Amory JK et al. Persistent intraprostatic androgen concentrations after medical castration in healthy men. J Clin Endocrinol Metab 2006; 91: 3850-3856. (Pubitemid 44536854)
-
(2006)
Journal of Clinical Endocrinology and Metabolism
, vol.91
, Issue.10
, pp. 3850-3856
-
-
Page, S.T.1
Lin, D.W.2
Mostaghel, E.A.3
Hess, D.L.4
True, L.D.5
Amory, J.K.6
Nelson, P.S.7
Matsumoto, A.M.8
Bremner, W.J.9
-
102
-
-
34250331066
-
Intraprostatic androgens and androgen-regulated gene expression persist after testosterone suppression: Therapeutic implications for castration-resistant prostate cancer
-
DOI 10.1158/0008-5472.CAN-06-3332
-
Mostaghel EA, Page ST, Lin DW, Fazli L, Coleman IM, True LD et al. Intraprostatic androgens and androgen-regulated gene expression persist after testosterone suppression: therapeutic implications for castration-resistant prostate cancer. Cancer Res 2007; 67: 5033-5041. (Pubitemid 46910214)
-
(2007)
Cancer Research
, vol.67
, Issue.10
, pp. 5033-5041
-
-
Mostaghel, E.A.1
Page, S.T.2
Lin, D.W.3
Fazli, L.4
Coleman, I.M.5
True, L.D.6
Knudsen, B.7
Hess, D.L.8
Nelson, C.C.9
Matsumoto, A.M.10
Bremner, W.J.11
Gleave, M.E.12
Nelson, P.S.13
-
103
-
-
0021220507
-
Comparison of prostatic cancer tissue dihydrotestosterone levels at the time of relapse following orchiectomy or estrogen therapy
-
Geller J, Albert JD, Nachtsheim DA, Loza D. Comparison of prostatic cancer tissue dihydrotestosterone levels at the time of relapse following orchiectomy or estrogen therapy. J Urol 1984; 132: 693-696. (Pubitemid 14017006)
-
(1984)
Journal of Urology
, vol.132
, Issue.4
, pp. 693-696
-
-
Geller, J.1
Albert, J.D.2
Nachtsheim, D.A.3
Loza, D.4
-
104
-
-
0022389768
-
Rationale for blockade of adrenal as well as testicular androgens in the treatment of advanced prostate cancer
-
Geller J. Rationale for blockade of adrenal as well as testicular androgens in the treatment of advanced prostate cancer. Semin Oncol 1985; 12: 28-35. (Pubitemid 15149394)
-
(1985)
Seminars in Oncology
, vol.12
, Issue.1 SUPPL. 1
, pp. 28-35
-
-
Geller, J.1
-
105
-
-
76249096762
-
Evidence of limited contributions for intratumoral steroidogenesis in prostate cancer
-
Hofland J, van Weerden WM, Dits NF, Steenbergen J, van Leenders GJ, Jenster G et al. Evidence of limited contributions for intratumoral steroidogenesis in prostate cancer. Cancer Res 2010; 70: 1256-1264.
-
(2010)
Cancer Res
, vol.70
, pp. 1256-1264
-
-
Hofland, J.1
Van Weerden, W.M.2
Dits, N.F.3
Steenbergen, J.4
Van Leenders, G.J.5
Jenster, G.6
-
106
-
-
68049131467
-
Reactivation of androgen receptor-regulated TMPRSS2:ERG gene expression in castration-resistant prostate cancer
-
Cai C, Wang H, Xu Y, Chen S, Balk SP. Reactivation of androgen receptor-regulated TMPRSS2:ERG gene expression in castration-resistant prostate cancer. Cancer Res 2009; 69: 6027-6032.
-
(2009)
Cancer Res
, vol.69
, pp. 6027-6032
-
-
Cai, C.1
Wang, H.2
Xu, Y.3
Chen, S.4
Balk, S.P.5
-
107
-
-
1542615071
-
Dysregulation of Sterol Response Element-Binding Proteins and Downstream Effectors in Prostate Cancer during Progression to Androgen Independence
-
DOI 10.1158/0008-5472.CAN-2148-2
-
Ettinger SL, Sobel R, Whitmore TG, Akbari M, Bradley DR, Gleave ME et al. Dys-regulation of sterol response element-binding proteins and downstream effectors in prostate cancer during progression to androgen independence. Cancer Res 2004; 64: 2212-2221. (Pubitemid 38339475)
-
(2004)
Cancer Research
, vol.64
, Issue.6
, pp. 2212-2221
-
-
Ettinger, S.L.1
Sobel, R.2
Whitmore, T.G.3
Akbari, M.4
Bradley, D.R.5
Gleave, M.E.6
Nelson, C.C.7
-
108
-
-
51049098138
-
Androgen levels increase by intratumoral de novo steroidogenesis during progression of castration-resistant prostate cancer
-
Locke JA, Guns ES, Lubik AA, Adomat HH, Hendy SC, Wood CA et al. Androgen levels increase by intratumoral de novo steroidogenesis during progression of castration-resistant prostate cancer. Cancer Res 2008; 68: 6407-6415.
-
(2008)
Cancer Res
, vol.68
, pp. 6407-6415
-
-
Locke, J.A.1
Guns, E.S.2
Lubik, A.A.3
Adomat, H.H.4
Hendy, S.C.5
Wood, C.A.6
-
109
-
-
67349187469
-
Steroidogenesis inhibitors alter but do not eliminate androgen synthesis mechanisms during progression to castration-resistance in LNCaP prostate xenografts
-
Locke JA, Nelson CC, Adomat HH, Hendy SC, Gleave ME, Guns ES. Steroidogenesis inhibitors alter but do not eliminate androgen synthesis mechanisms during progression to castration-resistance in LNCaP prostate xenografts. J Steroid Biochem Mol Biol 2009; 115: 126-136.
-
(2009)
J Steroid Biochem Mol Biol
, vol.115
, pp. 126-136
-
-
Locke, J.A.1
Nelson, C.C.2
Adomat, H.H.3
Hendy, S.C.4
Gleave, M.E.5
Guns, E.S.6
-
110
-
-
54849435425
-
Androgen-independent prostate cancer cells acquire the complete steroidogenic potential of synthesizing testosterone from cholesterol
-
Dillard PR, Lin MF, Khan SA. Androgen-independent prostate cancer cells acquire the complete steroidogenic potential of synthesizing testosterone from cholesterol. Mol Cell Endocrinol 2008; 295: 115-120.
-
(2008)
Mol Cell Endocrinol
, vol.295
, pp. 115-120
-
-
Dillard, P.R.1
Lin, M.F.2
Khan, S.A.3
-
111
-
-
80052827038
-
Resistance to CYP17A1 inhibition with abiraterone in castration-resistant prostate cancer: Induction of steroidogenesis and androgen receptor splice variants
-
Mostaghel EA, Marck BT, Plymate SR, Vessella RL, Balk S, Matsumoto AM et al. Resistance to CYP17A1 inhibition with abiraterone in castration-resistant prostate cancer: induction of steroidogenesis and androgen receptor splice variants. Clin Cancer Res 2011; 17: 5913-5925.
-
(2011)
Clin Cancer Res
, vol.17
, pp. 5913-5925
-
-
Mostaghel, E.A.1
Marck, B.T.2
Plymate, S.R.3
Vessella, R.L.4
Balk, S.5
Matsumoto, A.M.6
-
112
-
-
78649888666
-
The reti-noblastoma tumor suppressor controls androgen signaling and human prostate cancer progression
-
Sharma A, Yeow WS, Ertel A, Coleman I, Clegg N, Thangavel C et al. The reti-noblastoma tumor suppressor controls androgen signaling and human prostate cancer progression. J Clin Invest 2010; 120: 4478-4492.
-
(2010)
J Clin Invest
, vol.120
, pp. 4478-4492
-
-
Sharma, A.1
Yeow, W.S.2
Ertel, A.3
Coleman, I.4
Clegg, N.5
Thangavel, C.6
-
113
-
-
85003173512
-
Mutant androgen receptor detected in an advanced-stage prostatic carcinoma is activated by adrenal androgens and progesterone
-
DOI 10.1210/me.7.12.1541
-
Culig Z, Hobisch A, Cronauer MV, Cato AC, Hittmair A, Radmayr C et al. Mutant androgen receptor detected in an advanced-stage prostatic carcinoma is activated by adrenal androgens and progesterone. Mol Endocrinol 1993; 7: 1541-1550. (Pubitemid 24034236)
-
(1993)
Molecular Endocrinology
, vol.7
, Issue.12
, pp. 1541-1550
-
-
Culig, Z.1
Hobisch, A.2
Cronauer, M.V.3
Cato, A.C.B.4
Hittmair, A.5
Radmayr, C.6
Eberle, J.7
Bartsch, G.8
Klocker, H.9
-
114
-
-
0034125195
-
Glucocorticoids can promote androgen-independent growth of prostate cancer cells through a mutated androgen receptor
-
DOI 10.1038/76287
-
Zhao XY, Malloy PJ, Krishnan AV, Swami S, Navone NM, Peehl DM et al. Gluco-corticoids can promote androgen-independent growth of prostate cancer cells through a mutated androgen receptor. Nat Med 2000; 6: 703-706. (Pubitemid 30398797)
-
(2000)
Nature Medicine
, vol.6
, Issue.6
, pp. 703-706
-
-
Zhao, X.-Y.1
Malloy, P.J.2
Krishnan, A.V.3
Swami, S.4
Navone, N.M.5
Peehl, D.M.6
Feldman, D.7
-
115
-
-
0025644325
-
A mutation in the ligand binding domain of the androgen receptor of human LNCaP cells affects steroid binding characteristics and response to anti-andro-gens
-
Veldscholte J, Ris-Stalpers C, Kuiper GG, Jenster G, Berrevoets C, Claassen E et al. A mutation in the ligand binding domain of the androgen receptor of human LNCaP cells affects steroid binding characteristics and response to anti-andro-gens. Biochem Biophys Res Commun 1990; 173: 534-540.
-
(1990)
Biochem Biophys Res Commun
, vol.173
, pp. 534-540
-
-
Veldscholte, J.1
Ris-Stalpers, C.2
Kuiper, G.G.3
Jenster, G.4
Berrevoets, C.5
Claassen, E.6
-
116
-
-
0042130389
-
Androgen receptor mutations in androgen-independent prostate cancer: Cancer and leukemia group B study 9663
-
DOI 10.1200/JCO.2003.11.102
-
Taplin ME, Rajeshkumar B, Halabi S, Werner CP, Woda BA, Picus J et al. Androgen receptor mutations in androgen-independent prostate cancer: Cancer and Leukemia Group B Study 9663. J Clin Oncol 2003; 21: 2673-2678. (Pubitemid 46606310)
-
(2003)
Journal of Clinical Oncology
, vol.21
, Issue.14
, pp. 2673-2678
-
-
Taplin, M.-E.1
Rajeshkumar, B.2
Halabi, S.3
Werner, C.P.4
Woda, B.A.5
Picus, J.6
Stadler, W.7
Hayes, D.F.8
Kantoff, P.W.9
Vogelzang, N.J.10
Small, E.J.11
-
117
-
-
48549089747
-
Splicing of a novel androgen receptor exon generates a constitutively active androgen receptor that mediates prostate cancer therapy resistance
-
Dehm SM, Schmidt LJ, Heemers HV, Vessella RL, Tindall DJ. Splicing of a novel androgen receptor exon generates a constitutively active androgen receptor that mediates prostate cancer therapy resistance. Cancer Res 2008; 68: 5469-5477.
-
(2008)
Cancer Res
, vol.68
, pp. 5469-5477
-
-
Dehm, S.M.1
Schmidt, L.J.2
Heemers, H.V.3
Vessella, R.L.4
Tindall, D.J.5
-
118
-
-
65549168746
-
A novel androgen receptor splice variant is up-regulated during prostate cancer progression and promotes androgen depletion-resistant growth
-
Guo Z, Yang X, Sun F, Jiang R, Linn DE, Chen H et al. A novel androgen receptor splice variant is up-regulated during prostate cancer progression and promotes androgen depletion-resistant growth. Cancer Res 2009; 69: 2305-2313.
-
(2009)
Cancer Res
, vol.69
, pp. 2305-2313
-
-
Guo, Z.1
Yang, X.2
Sun, F.3
Jiang, R.4
Linn, D.E.5
Chen, H.6
-
119
-
-
58249110391
-
Ligand-inde-pendent androgen receptor variants derived from splicing of cryptic exons signify hormone-refractory prostate cancer
-
Hu R, Dunn TA, Wei S, Isharwal S, Veltri RW, Humphreys E et al. Ligand-inde-pendent androgen receptor variants derived from splicing of cryptic exons signify hormone-refractory prostate cancer. Cancer Res 2009; 69: 16-22.
-
(2009)
Cancer Res
, vol.69
, pp. 16-22
-
-
Hu, R.1
Dunn, T.A.2
Wei, S.3
Isharwal, S.4
Veltri, R.W.5
Humphreys, E.6
-
120
-
-
78049280194
-
Con-stitutively active androgen receptor splice variants expressed in castration-resistant prostate cancer require full-length androgen receptor
-
Watson PA, Chen YF, Balbas MD, Wongvipat J, Socci ND, Viale A et al. Con-stitutively active androgen receptor splice variants expressed in castration-resistant prostate cancer require full-length androgen receptor. Proc Natl Acad Sci USA 2010; 107: 16759-16765.
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, pp. 16759-16765
-
-
Watson, P.A.1
Chen, Y.F.2
Balbas, M.D.3
Wongvipat, J.4
Socci, N.D.5
Viale, A.6
-
121
-
-
80054931284
-
Alternatively spliced androgen receptor variants
-
Dehm SM, Tindall DJ. Alternatively spliced androgen receptor variants. Endocr Relat Cancer 2011; 18: R183-R196.
-
(2011)
Endocr Relat Cancer
, vol.18
-
-
Dehm, S.M.1
Tindall, D.J.2
-
122
-
-
77955296562
-
Castration resistance in human prostate cancer is conferred by a frequently occurring androgen receptor splice variant
-
Sun S, Sprenger CC, Vessella RL, Haugk K, Soriano K, Mostaghel EA et al. Castration resistance in human prostate cancer is conferred by a frequently occurring androgen receptor splice variant. J Clin Invest 2010; 120: 2715-2730.
-
(2010)
J Clin Invest
, vol.120
, pp. 2715-2730
-
-
Sun, S.1
Sprenger, C.C.2
Vessella, R.L.3
Haugk, K.4
Soriano, K.5
Mostaghel, E.A.6
-
123
-
-
81255150464
-
Androgen receptor variants occur frequently in castration resistant prostate cancer metastases
-
Zhang X, Morrissey C, Sun S, Ketchandji M, Nelson PS, True LD et al. Androgen receptor variants occur frequently in castration resistant prostate cancer metastases. PLoS ONE 2011; 6: e27970.
-
(2011)
PLoS ONE
, vol.6
-
-
Zhang, X.1
Morrissey, C.2
Sun, S.3
Ketchandji, M.4
Nelson, P.S.5
True, L.D.6
-
124
-
-
84869094406
-
AR intragenic deletions linked to androgen receptor splice variant expression and activity in models of prostate cancer progression
-
Li Y, Hwang TH, Oseth LA, Hauge A, Vessella RL, Schmechel SC et al. AR intragenic deletions linked to androgen receptor splice variant expression and activity in models of prostate cancer progression. Oncogene 2012; 31: 4759-4767.
-
(2012)
Oncogene
, vol.31
, pp. 4759-4767
-
-
Li, Y.1
Hwang, T.H.2
Oseth, L.A.3
Hauge, A.4
Vessella, R.L.5
Schmechel, S.C.6
-
125
-
-
77953280591
-
Regression of castrate-recurrent prostate cancer by a small-molecule inhibitor of the amino-terminus domain of the androgen receptor
-
Andersen RJ, Mawji NR, Wang J, Wang G, Haile S, Myung JK et al. Regression of castrate-recurrent prostate cancer by a small-molecule inhibitor of the amino-terminus domain of the androgen receptor. Cancer Cell 2010; 17: 535-546.
-
(2010)
Cancer Cell
, vol.17
, pp. 535-546
-
-
Andersen, R.J.1
Mawji, N.R.2
Wang, J.3
Wang, G.4
Haile, S.5
Myung, J.K.6
-
126
-
-
34347263425
-
Activated Cdc42-associated kinase Ack1 promotes prostate cancer progression via androgen receptor tyrosine phosphorylation
-
DOI 10.1073/pnas.0700420104
-
Mahajan NP, Liu Y, Majumder S, Warren MR, Parker CE, Mohler JL et al. Activated Cdc42-associated kinase Ack1 promotes prostate cancer progression via androgen receptor tyrosine phosphorylation. Proc Natl Acad Sci USA 2007; 104: 8438-8443. (Pubitemid 47175506)
-
(2007)
Proceedings of the National Academy of Sciences of the United States of America
, vol.104
, Issue.20
, pp. 8438-8443
-
-
Mahajan, N.P.1
Liu, Y.2
Majumder, S.3
Warren, M.R.4
Parker, C.E.5
Mohler, J.L.6
Earp, H.S.7
Whang, Y.E.8
-
127
-
-
33749445413
-
Regulation of androgen receptor activity by tyrosine phosphorylation
-
DOI 10.1016/j.ccr.2006.08.021, PII S1535610806002777
-
Guo Z, Dai B, Jiang T, Xu K, Xie Y, Kim O et al. Regulation of androgen receptor activity by tyrosine phosphorylation. Cancer Cell 2006; 10: 309-319. (Pubitemid 44512189)
-
(2006)
Cancer Cell
, vol.10
, Issue.4
, pp. 309-319
-
-
Guo, Z.1
Dai, B.2
Jiang, T.3
Xu, K.4
Xie, Y.5
Kim, O.6
Nesheiwat, I.7
Kong, X.8
Melamed, J.9
Handratta, V.D.10
Njar, V.C.O.11
Brodie, A.M.H.12
Yu, L.-R.13
Veenstra, T.D.14
Chen, H.15
Qiu, Y.16
-
128
-
-
33845298019
-
Receptor for activated C kinase 1 (RACK1) and Src regulate the tyrosine phosphorylation and function of the androgen receptor
-
DOI 10.1158/0008-5472.CAN-06-0596
-
Kraus S, Gioeli D, Vomastek T, Gordon V, Weber MJ. Receptor for activated C kinase 1 (RACK1) and Src regulate the tyrosine phosphorylation and function of the androgen receptor. Cancer Res 2006; 66: 11047-11054. (Pubitemid 44877005)
-
(2006)
Cancer Research
, vol.66
, Issue.22
, pp. 11047-11054
-
-
Kraus, S.1
Gioeli, D.2
Vomastek, T.3
Gordon, V.4
Weber, M.J.5
-
129
-
-
84863245741
-
Androgen receptor serine 81 phosphorylation mediates chromatin binding and transcriptional activation
-
Chen S, Gulla S, Cai C, Balk SP. Androgen receptor serine 81 phosphorylation mediates chromatin binding and transcriptional activation. J Biol Chem 2012; 287: 8571-8583.
-
(2012)
J Biol Chem
, vol.287
, pp. 8571-8583
-
-
Chen, S.1
Gulla, S.2
Cai, C.3
Balk, S.P.4
-
130
-
-
33750452673
-
Androgen receptor phosphorylation and stabilization in prostate cancer by cyclin-dependent kinase 1
-
DOI 10.1073/pnas.0604193103
-
Chen S, Xu Y, Yuan X, Bubley GJ, Balk SP. Androgen receptor phosphorylation and stabilization in prostate cancer by cyclin-dependent kinase 1. Proc Natl Acad Sci USA 2006; 103: 15969-15974. (Pubitemid 44657576)
-
(2006)
Proceedings of the National Academy of Sciences of the United States of America
, vol.103
, Issue.43
, pp. 15969-15974
-
-
Chen, S.1
Xu, Y.2
Yuan, X.3
Bubley, G.J.4
Balk, S.P.5
-
131
-
-
78649427492
-
CDK9 regulates AR promoter selectivity and cell growth through serine 81 phos-phorylation
-
Gordon V, Bhadel S, Wunderlich W, Zhang J, Ficarro SB, Mollah SA et al. CDK9 regulates AR promoter selectivity and cell growth through serine 81 phos-phorylation. Mol Endocrinol 2010; 24: 2267-2280.
-
(2010)
Mol Endocrinol
, vol.24
, pp. 2267-2280
-
-
Gordon, V.1
Bhadel, S.2
Wunderlich, W.3
Zhang, J.4
Ficarro, S.B.5
Mollah, S.A.6
-
132
-
-
0347696003
-
Suppression Versus Induction of Androgen Receptor Functions by the Phosphatidylinositol 3-Kinase/Akt Pathway in Prostate Cancer LNCaP Cells with Different Passage Numbers
-
DOI 10.1074/jbc.M300676200
-
Lin HK, Hu YC, Yang L, Altuwaijri S, Chen YT, Kang HY et al. Suppression versus induction of androgen receptor functions by the phosphatidylinositol 3-kinase/Akt pathway in prostate cancer LNCaP cells with different passage numbers. J Biol Chem 2003; 278: 50902-50907. (Pubitemid 38020321)
-
(2003)
Journal of Biological Chemistry
, vol.278
, Issue.51
, pp. 50902-50907
-
-
Lin, H.-K.1
Hu, Y.-C.2
Yang, L.3
Altuwaijri, S.4
Chen, Y.-T.5
Kang, H.-Y.6
Chang, C.7
-
133
-
-
0035912833
-
Akt suppresses androgen-induced apoptosis by phosphorylating and inhibiting androgen receptor
-
DOI 10.1073/pnas.121173298
-
Lin HK, Yeh S, Kang HY, Chang C. Akt suppresses androgen-induced apoptosis by phosphorylating and inhibiting androgen receptor. Proc Natl Acad Sci USA 2001; 98: 7200-7205. (Pubitemid 32567926)
-
(2001)
Proceedings of the National Academy of Sciences of the United States of America
, vol.98
, Issue.13
, pp. 7200-7205
-
-
Lin, H.-K.1
Yeh, S.2
Kang, H.-Y.3
Chang, C.4
-
134
-
-
28844467498
-
Cell-specific regulation of androgen receptor phosphorylation in vivo
-
DOI 10.1074/jbc.M508442200
-
Taneja SS, Ha S, Swenson NK, Huang HY, Lee P, Melamed J et al. Cell-specific regulation of androgen receptor phosphorylation in vivo. J Biol Chem 2005; 280: 40916-40924. (Pubitemid 41780585)
-
(2005)
Journal of Biological Chemistry
, vol.280
, Issue.49
, pp. 40916-40924
-
-
Taneja, S.S.1
Ha, S.2
Swenson, N.K.3
Huang, H.Y.4
Lee, P.5
Melamed, J.6
Shapiro, E.7
Garabedian, M.J.8
Logan, S.K.9
-
135
-
-
84883199057
-
Phosphorylation of the androgen receptor by PIM1 in hormone refractory prostate cancer
-
(e-pub ahead of print 17 September 2012; doi:10.1038/onc.2012.412)
-
Ha S, Iqbal NJ, Mita P, Ruoff R, Gerald WL, Lepor H et al. Phosphorylation of the androgen receptor by PIM1 in hormone refractory prostate cancer. Oncogene (e-pub ahead of print 17 September 2012; doi:10.1038/onc.2012. 412).
-
Oncogene
-
-
Ha, S.1
Iqbal, N.J.2
Mita, P.3
Ruoff, R.4
Gerald, W.L.5
Lepor, H.6
-
136
-
-
13744257306
-
Regulation of androgen receptor and histone deacetylase 1 by Mdm2-mediated ubiquitylation
-
DOI 10.1093/nar/gki141
-
Gaughan L, Logan IR, Neal DE, Robson CN. Regulation of androgen receptor and histone deacetylase 1 by Mdm2-mediated ubiquitylation. Nucleic Acids Res 2005; 33: 13-26. (Pubitemid 40276925)
-
(2005)
Nucleic Acids Research
, vol.33
, Issue.1
, pp. 13-26
-
-
Gaughan, L.1
Logan, I.R.2
Neal, D.E.3
Robson, C.N.4
-
137
-
-
79953179324
-
Androgen receptor levels are upregulated by Akt in prostate cancer
-
Ha S, Ruoff R, Kahoud N, Logan SK, Franke TF. Androgen receptor levels are upregulated by Akt in prostate cancer. Endocr Relat Cancer 2011; 18: 245-255.
-
(2011)
Endocr Relat Cancer
, vol.18
, pp. 245-255
-
-
Ha, S.1
Ruoff, R.2
Kahoud, N.3
Logan, S.K.4
Franke, T.F.5
-
138
-
-
0036683093
-
Phosphorylation-dependent ubiquitylation and degradation of androgen receptor by Akt require Mdm2 E3 ligase
-
DOI 10.1093/emboj/cdf406
-
Lin HK, Wang L, Hu YC, Altuwaijri S, Chang C. Phosphorylation-dependent ubi-quitylation and degradation of androgen receptor by Akt require Mdm2 E3 ligase. EMBO J 2002; 21: 4037-4048. (Pubitemid 34857436)
-
(2002)
EMBO Journal
, vol.21
, Issue.15
, pp. 4037-4048
-
-
Lin, H.-K.1
Wang, L.2
Hu, Y.-C.3
Altuwaijri, S.4
Chang, C.5
-
139
-
-
79955975429
-
Reciprocal feedback regulation of PI3K and androgen receptor signaling in PTEN-deficient prostate cancer
-
Carver BS, Chapinski C, Wongvipat J, Hieronymus H, Chen Y, Chandarlapaty S et al. Reciprocal feedback regulation of PI3K and androgen receptor signaling in PTEN-deficient prostate cancer. Cancer Cell 2011; 19: 575-586.
-
(2011)
Cancer Cell
, vol.19
, pp. 575-586
-
-
Carver, B.S.1
Chapinski, C.2
Wongvipat, J.3
Hieronymus, H.4
Chen, Y.5
Chandarlapaty, S.6
-
140
-
-
79958764107
-
Cell autonomous role of PTEN in regulating castration-resistant prostate cancer growth
-
Mulholland DJ, Tran LM, Li Y, Cai H, Morim A, Wang S et al. Cell autonomous role of PTEN in regulating castration-resistant prostate cancer growth. Cancer Cell 2011; 19: 792-804.
-
(2011)
Cancer Cell
, vol.19
, pp. 792-804
-
-
Mulholland, D.J.1
Tran, L.M.2
Li, Y.3
Cai, H.4
Morim, A.5
Wang, S.6
-
141
-
-
33344467745
-
Stress kinase signaling regulates androgen receptor phosphorylation, transcription, and localization
-
DOI 10.1210/me.2005-0351
-
Gioeli D, Black BE, Gordon V, Spencer A, Kesler CT, Eblen ST et al. Stress kinase signaling regulates androgen receptor phosphorylation, transcription, and localization. Mol Endocrinol 2006; 20: 503-515. (Pubitemid
-
(2006)
Molecular Endocrinology
, vol.20
, Issue.3
, pp. 503-515
-
-
Gioeli, D.1
Black, B.E.2
Gordon, V.3
Spencer, A.4
Kesler, C.T.5
Eblen, S.T.6
Paschal, B.M.7
Weber, M.J.8
-
142
-
-
70350036005
-
Androgen receptor phosphorylation and activity are regulated by an association with protein phosphatase 1
-
Chen S, Kesler CT, Paschal BM, Balk SP. Androgen receptor phosphorylation and activity are regulated by an association with protein phosphatase 1. J Biol Chem 2009; 284: 25576-25584.
-
(2009)
J Biol Chem
, vol.284
, pp. 25576-25584
-
-
Chen, S.1
Kesler, C.T.2
Paschal, B.M.3
Balk, S.P.4
-
143
-
-
63249104202
-
Regulation of androgen receptor transcriptional activity and specificity by RNF6-induced ubiquitination
-
Xu K, Shimelis H, Linn DE, Jiang R, Yang X, Sun F et al. Regulation of androgen receptor transcriptional activity and specificity by RNF6-induced ubiquitination. Cancer Cell 2009; 15: 270-282.
-
(2009)
Cancer Cell
, vol.15
, pp. 270-282
-
-
Xu, K.1
Shimelis, H.2
Linn, D.E.3
Jiang, R.4
Yang, X.5
Sun, F.6
-
144
-
-
79952171495
-
Regulation of the androgen receptor by SET9-mediated methylation
-
Gaughan L, Stockley J, Wang N, McCracken SR, Treumann A, Armstrong K et al. Regulation of the androgen receptor by SET9-mediated methylation. Nucleic Acids Res 2011; 39: 1266-1279.
-
(2011)
Nucleic Acids Res
, vol.39
, pp. 1266-1279
-
-
Gaughan, L.1
Stockley, J.2
Wang, N.3
McCracken, S.R.4
Treumann, A.5
Armstrong, K.6
-
145
-
-
79952155998
-
Lysine methylation and functional modulation of androgen receptor by Set9 methyltransferase
-
Ko S, Ahn J, Song CS, Kim S, Knapczyk-Stwora K, Chatterjee B. Lysine methylation and functional modulation of androgen receptor by Set9 methyltransferase. Mol Endocrinol 2011; 25: 433-444.
-
(2011)
Mol Endocrinol
, vol.25
, pp. 433-444
-
-
Ko, S.1
Ahn, J.2
Song, C.S.3
Kim, S.4
Knapczyk-Stwora, K.5
Chatterjee, B.6
-
146
-
-
0035361340
-
A mechanism for androgen receptor-mediated prostate cancer recurrence after androgen deprivation therapy
-
Gregory CW, He B, Johnson RT, Ford OH, Mohler JL, French FS et al. A mechanism for androgen receptor-mediated prostate cancer recurrence after androgen deprivation therapy. Cancer Res 2001; 61: 4315-4319. (Pubitemid 32685750)
-
(2001)
Cancer Research
, vol.61
, Issue.11
, pp. 4315-4319
-
-
Gregory, C.W.1
He, B.2
Johnson, R.T.3
Ford, O.H.4
Mohler, J.L.5
French, F.S.6
Wilson, E.M.7
-
147
-
-
1342325380
-
Epidermal Growth Factor Increases Coactivation of the Androgen Receptor in Recurrent Prostate Cancer
-
DOI 10.1074/jbc.M307649200
-
Gregory CW, Fei X, Ponguta LA, He B, Bill HM, French FS et al. Epidermal growth factor increases coactivation of the androgen receptor in recurrent prostate cancer. J Biol Chem 2004; 279: 7119-7130. (Pubitemid 38248859)
-
(2004)
Journal of Biological Chemistry
, vol.279
, Issue.8
, pp. 7119-7130
-
-
Gregory, C.W.1
Fei, X.2
Ponguta, L.A.3
He, B.4
Bill, H.M.5
French, F.S.6
Wilson, E.M.7
-
148
-
-
24744442616
-
Role of SRC-1 in the promotion of prostate cancer cell growth and tumor progression
-
DOI 10.1158/0008-5472.CAN-04-3541
-
Agoulnik IU, Vaid A, Bingman 3rd WE, Erdeme H, Frolov A, Smith CL et al. Role of SRC-1 in the promotion of prostate cancer cell growth and tumor progression. Cancer Res 2005; 65: 7959-7967. (Pubitemid 41297275)
-
(2005)
Cancer Research
, vol.65
, Issue.17
, pp. 7959-7967
-
-
Agoulnik, I.U.1
Vaid, A.2
Bingman III, W.E.3
Erdeme, H.4
Frolov, A.5
Smith, C.L.6
Ayala, G.7
Ittmann, M.M.8
Weigel, N.L.9
-
149
-
-
33751304953
-
Androgens modulate expression of transcription intermediary factor 2, an androgen receptor coactivator whose expression level correlates with early biochemical recurrence in prostate cancer
-
DOI 10.1158/0008-5472.CAN-06-1023
-
Agoulnik IU, Vaid A, Nakka M, Alvarado M, Bingman 3rd WE, Erdem H et al. Androgens modulate expression of transcription intermediary factor 2, an androgen receptor coactivator whose expression level correlates with early biochemical recurrence in prostate cancer. Cancer Res 2006; 66: 10594-10602. (Pubitemid 44799783)
-
(2006)
Cancer Research
, vol.66
, Issue.21
, pp. 10594-10602
-
-
Agoulnik, I.U.1
Vaid, A.2
Nakka, M.3
Alvarado, M.4
Bingman III, W.E.5
Erdem, H.6
Frolov, A.7
Smith, C.L.8
Ayala, G.E.9
Ittmann, M.M.10
Weigel, N.L.11
-
150
-
-
77954255681
-
Inte-grative genomic profiling of human prostate cancer
-
Taylor BS, Schultz N, Hieronymus H, Gopalan A, Xiao Y, Carver BS et al. Inte-grative genomic profiling of human prostate cancer. Cancer Cell 2010; 18: 11-22.
-
(2010)
Cancer Cell
, vol.18
, pp. 11-22
-
-
Taylor, B.S.1
Schultz, N.2
Hieronymus, H.3
Gopalan, A.4
Xiao, Y.5
Carver, B.S.6
-
151
-
-
33646138230
-
JHDM2A, a JmjC-containing H3K9 demethylase, facilitates transcription activation by androgen receptor
-
Yamane K, Toumazou C, Tsukada Y, Erdjument-Bromage H, Tempst P, Wong J et al. JHDM2A, a JmjC-containing H3K9 demethylase, facilitates transcription activation by androgen receptor. Cell 2006; 125: 483-495.
-
(2006)
Cell
, vol.125
, pp. 483-495
-
-
Yamane, K.1
Toumazou, C.2
Tsukada, Y.3
Erdjument-Bromage, H.4
Tempst, P.5
Wong, J.6
-
152
-
-
84863723010
-
The mutational landscape of lethal castration-resistant prostate cancer
-
Grasso CS, Wu YM, Robinson DR, Cao X, Dhanasekaran SM, Khan AP et al. The mutational landscape of lethal castration-resistant prostate cancer. Nature 2012; 487: 239-243.
-
(2012)
Nature
, vol.487
, pp. 239-243
-
-
Grasso, C.S.1
Wu, Y.M.2
Robinson, D.R.3
Cao, X.4
Dhanasekaran, S.M.5
Khan, A.P.6
-
153
-
-
80054751998
-
Exome sequencing identifies a spectrum of mutation frequencies in advanced and lethal prostate cancers
-
Kumar A, White TA, MacKenzie AP, Clegg N, Lee C, Dumpit RF et al. Exome sequencing identifies a spectrum of mutation frequencies in advanced and lethal prostate cancers. Proc Natl Acad Sci USA 2011; 108: 17087-17092.
-
(2011)
Proc Natl Acad Sci USA
, vol.108
, pp. 17087-17092
-
-
Kumar, A.1
White, T.A.2
Mackenzie, A.P.3
Clegg, N.4
Lee, C.5
Dumpit, R.F.6
-
154
-
-
17844376217
-
Structural basis for antagonism and resistance of bicalutamide in prostate cancer
-
DOI 10.1073/pnas.0500381102
-
Bohl CE, Gao W, Miller DD, Bell CE, Dalton JT. Structural basis for antagonism and resistance of bicalutamide in prostate cancer. Proc Natl Acad Sci USA 2005; 102: 6201-6206. (Pubitemid 40594278)
-
(2005)
Proceedings of the National Academy of Sciences of the United States of America
, vol.102
, Issue.17
, pp. 6201-6206
-
-
Bohl, C.E.1
Gao, W.2
Miller, D.D.3
Bell, C.E.4
Dalton, J.T.5
-
155
-
-
34250365377
-
Crystal structure of the T877A human androgen receptor ligand-binding domain complexed to cyproterone acetate provides insight for ligand-induced conformational changes and structure-based drug design
-
DOI 10.1074/jbc.M611711200
-
Bohl CE, Wu Z, Miller DD, Bell CE, Dalton JT. Crystal structure of the T877A human androgen receptor ligand-binding domain complexed to cyproterone acetate provides insight for ligand-induced conformational changes and structure-based drug design. J Biol Chem 2007; 282: 13648-13655. (Pubitemid 47100516)
-
(2007)
Journal of Biological Chemistry
, vol.282
, Issue.18
, pp. 13648-13655
-
-
Bohl, C.E.1
Wu, Z.2
Miller, D.D.3
Bell, C.E.4
Dalton, J.T.5
-
156
-
-
0037135630
-
Bicalutamide functions as an androgen receptor antagonist by assembly of a transcriptionally inactive receptor
-
DOI 10.1074/jbc.M203310200
-
Masiello D, Cheng S, Bubley GJ, Lu ML, Balk SP. Bicalutamide functions as an androgen receptor antagonist by assembly of a transcriptionally inactive receptor. J Biol Chem 2002; 277: 26321-26326. (Pubitemid 34967123)
-
(2002)
Journal of Biological Chemistry
, vol.277
, Issue.29
, pp. 26321-26326
-
-
Masiello, D.1
Cheng, S.2
Bubley, G.J.3
Lu, M.L.4
Balk, S.P.5
-
157
-
-
27144466425
-
Antiandrogens prevent stable DNA-binding of the androgen receptor
-
DOI 10.1242/jcs.02546
-
Farla P, Hersmus R, Trapman J, Houtsmuller AB. Antiandrogens prevent stable DNA-binding of the androgen receptor. J Cell Sci 2005; 118: 4187-4198. (Pubitemid 41488956)
-
(2005)
Journal of Cell Science
, vol.118
, Issue.18
, pp. 4187-4198
-
-
Farla, P.1
Hersmus, R.2
Trapman, J.3
Houtsmuller, A.B.4
-
158
-
-
65649090203
-
Development of a second-generation antiandrogen for treatment of advanced prostate cancer
-
Tran C, Ouk S, Clegg NJ, Chen Y, Watson PA, Arora V et al. Development of a second-generation antiandrogen for treatment of advanced prostate cancer. Science 2009; 324: 787-790.
-
(2009)
Science
, vol.324
, pp. 787-790
-
-
Tran, C.1
Ouk, S.2
Clegg, N.J.3
Chen, Y.4
Watson, P.A.5
Arora, V.6
-
159
-
-
84863230424
-
ARN-509: A novel antiandrogen for prostate cancer treatment
-
Clegg NJ, Wongvipat J, Joseph JD, Tran C, Ouk S, Dilhas A et al. ARN-509: a novel antiandrogen for prostate cancer treatment. Cancer Res 2012; 72: 1494-1503.
-
(2012)
Cancer Res
, vol.72
, pp. 1494-1503
-
-
Clegg, N.J.1
Wongvipat, J.2
Joseph, J.D.3
Tran, C.4
Ouk, S.5
Dilhas, A.6
-
160
-
-
84868089097
-
In silico discovery of androgen receptor antagonists with activity in castration resistant prostate cancer
-
Shen HC, Shanmugasundaram K, Simon NI, Cai C, Wang H, Chen S et al. In silico discovery of androgen receptor antagonists with activity in castration resistant prostate cancer. Mol Endocrinol 2012; 26: 1836-1846.
-
(2012)
Mol Endocrinol
, vol.26
, pp. 1836-1846
-
-
Shen, H.C.1
Shanmugasundaram, K.2
Simon, N.I.3
Cai, C.4
Wang, H.5
Chen, S.6
-
161
-
-
8344272750
-
Coregulator recruitment and histone modifications in transcriptional regulation by the androgen receptor
-
DOI 10.1210/me.2004-0245
-
Kang Z, Janne OA, Palvimo JJ. Coregulator recruitment and histone modifications in transcriptional regulation by the androgen receptor. Mol Endocrinol 2004; 18: 2633-2648. (Pubitemid 39482054)
-
(2004)
Molecular Endocrinology
, vol.18
, Issue.11
, pp. 2633-2648
-
-
Kang, Z.1
Janne, O.A.2
Palvimo, J.J.3
-
162
-
-
55749094858
-
Structural basis for nuclear receptor corepressor recruitment by antagonist-liganded androgen receptor
-
Hodgson MC, Shen HC, Hollenberg AN, Balk SP. Structural basis for nuclear receptor corepressor recruitment by antagonist-liganded androgen receptor. Mol Cancer Ther 2008; 7: 3187-3194.
-
(2008)
Mol Cancer Ther
, vol.7
, pp. 3187-3194
-
-
Hodgson, M.C.1
Shen, H.C.2
Hollenberg, A.N.3
Balk, S.P.4
-
163
-
-
34548595236
-
Activity of androgen receptor antagonist bicalutamide in prostate cancer cells is independent of NCoR and SMRT corepressors
-
DOI 10.1158/0008-5472.CAN-07-0617
-
Hodgson MC, Astapova I, Hollenberg AN, Balk SP. Activity of androgen receptor antagonist bicalutamide in prostate cancer cells is independent of NCoR and SMRT corepressors. Cancer Res 2007; 67: 8388-8395. (Pubitemid 47395178)
-
(2007)
Cancer Research
, vol.67
, Issue.17
, pp. 8388-8395
-
-
Hodgson, M.C.1
Astapova, I.2
Hollenberg, A.N.3
Balk, S.P.4
-
164
-
-
32044448683
-
Macrophage/cancer cell interactions mediate hormone resistance by a nuclear receptor derepression pathway
-
DOI 10.1016/j.cell.2005.12.032, PII S0092867406000067
-
Zhu P, Baek SH, Bourk EM, Ohgi KA, Garcia-Bassets I, Sanjo H et al. Macrophage/cancer cell interactions mediate hormone resistance by a nuclear receptor derepression pathway. Cell 2006; 124: 615-629. (Pubitemid 43199445)
-
(2006)
Cell
, vol.124
, Issue.3
, pp. 615-629
-
-
Zhu, P.1
Baek, S.H.2
Bourk, E.M.3
Ohgi, K.A.4
Garcia-Bassets, I.5
Sanjo, H.6
Akira, S.7
Kotol, P.F.8
Glass, C.K.9
Rosenfeld, M.G.10
Rose, D.W.11
|