메뉴 건너뛰기




Volumn 66, Issue 15, 2006, Pages 7783-7792

Androgens induce prostate cancer cell proliferation through mammalian target of rapamycin activation and post-transcriptional increases in cyclin D proteins

Author keywords

[No Author keywords available]

Indexed keywords

ANDROGEN; ANDROSTANOLONE; CYCLIN D; CYCLIN D1; CYCLIN D2; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; INITIATION FACTOR 4E BINDING PROTEIN 1; MAMMALIAN TARGET OF RAPAMYCIN; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN P70; RAPAMYCIN; S6 KINASE; TUBERIN;

EID: 33747880070     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-05-4472     Document Type: Article
Times cited : (236)

References (52)
  • 1
    • 0036645414 scopus 로고    scopus 로고
    • Molecular biology of the androgen receptor
    • Gelmann EP. Molecular biology of the androgen receptor. J Clin Oncol 2002;20:3001-15.
    • (2002) J Clin Oncol , vol.20 , pp. 3001-3015
    • Gelmann, E.P.1
  • 3
    • 0025644325 scopus 로고
    • A mutation in the ligand binding domain of the androgen receptor of human LNCaP cells affects steroid binding characteristics and response to anti-androgens
    • Veldscholte J, Ris-Stalpers C, Kuiper GG, et al. A mutation in the ligand binding domain of the androgen receptor of human LNCaP cells affects steroid binding characteristics and response to anti-androgens. Biochem Biophys Res Commun 1990;173:534-40.
    • (1990) Biochem Biophys Res Commun , vol.173 , pp. 534-540
    • Veldscholte, J.1    Ris-Stalpers, C.2    Kuiper, G.G.3
  • 4
    • 0041914332 scopus 로고    scopus 로고
    • The role of PTEN in the progression and survival of prostate cancer
    • Deocampo ND, Huang H, Tindall DJ. The role of PTEN in the progression and survival of prostate cancer. Minerva Endocrinol 2003;28:145-53.
    • (2003) Minerva Endocrinol , vol.28 , pp. 145-153
    • Deocampo, N.D.1    Huang, H.2    Tindall, D.J.3
  • 5
    • 0032493489 scopus 로고    scopus 로고
    • 1 regulatory elements control the androgen-dependent proliferation of prostatic carcinoma cells
    • 1 regulatory elements control the androgen-dependent proliferation of prostatic carcinoma cells. J Biol Chem 1998;273:20213-22.
    • (1998) J Biol Chem , vol.273 , pp. 20213-20222
    • Knudsen, K.E.1    Arden, K.C.2    Cavenee, W.K.3
  • 6
    • 0032537009 scopus 로고    scopus 로고
    • Increased cell growth and tumorigenicity in human prostate LNCaP cells by overexpression to cyclin D1
    • Chen Y, Martinez LA, LaCava M, Coghlan L, Conti CJ. Increased cell growth and tumorigenicity in human prostate LNCaP cells by overexpression to cyclin D1. Oncogene 1998;16:1913-20.
    • (1998) Oncogene , vol.16 , pp. 1913-1920
    • Chen, Y.1    Martinez, L.A.2    LaCava, M.3    Coghlan, L.4    Conti, C.J.5
  • 7
    • 0033865682 scopus 로고    scopus 로고
    • Differential requirements for ras and the retinoblastoma tumor suppressor protein in the androgen dependence of prostatic adenocarcinoma cells
    • Fribourg AF, Knudsen KE, Strobeck MW, Lindhorst CM, Knudsen ES. Differential requirements for ras and the retinoblastoma tumor suppressor protein in the androgen dependence of prostatic adenocarcinoma cells. Cell Growth Differ 2000;11:361-72.
    • (2000) Cell Growth Differ , vol.11 , pp. 361-372
    • Fribourg, A.F.1    Knudsen, K.E.2    Strobeck, M.W.3    Lindhorst, C.M.4    Knudsen, E.S.5
  • 8
    • 0030876442 scopus 로고    scopus 로고
    • Regulation of androgen-dependent prostatic cancer cell growth: Androgen regulation of CDK2, CDK4, and CK1 p16 genes
    • Lu S, Tsai SY, Tsai MJ. Regulation of androgen-dependent prostatic cancer cell growth: androgen regulation of CDK2, CDK4, and CK1 p16 genes. Cancer Res 1997;57:4511-6.
    • (1997) Cancer Res , vol.57 , pp. 4511-4516
    • Lu, S.1    Tsai, S.Y.2    Tsai, M.J.3
  • 9
    • 0035192219 scopus 로고    scopus 로고
    • Androgen stimulated cellular proliferation in the human prostate cancer cell line LNCaP is associated with reduced retinoblastoma protein expression
    • Taneja SS, Ha S, Garabedian MJ. Androgen stimulated cellular proliferation in the human prostate cancer cell line LNCaP is associated with reduced retinoblastoma protein expression. J Cell Biochem 2001;84:188-99.
    • (2001) J Cell Biochem , vol.84 , pp. 188-199
    • Taneja, S.S.1    Ha, S.2    Garabedian, M.J.3
  • 11
    • 0029960504 scopus 로고    scopus 로고
    • 1 cyclins, cyclin-dependent kinases, and cyclin-dependent kinase inhibitors in androgen-induced prostate proliferation in castrated rats
    • 1 cyclins, cyclin-dependent kinases, and cyclin-dependent kinase inhibitors in androgen-induced prostate proliferation in castrated rats. Cell Growth Differ 1996;7:1571-8.
    • (1996) Cell Growth Differ , vol.7 , pp. 1571-1578
    • Chen, Y.1    Robles, A.I.2    Martinez, L.A.3    Liu, F.4    Gimenez-Conti, I.B.5    Conti, C.J.6
  • 12
    • 0033520806 scopus 로고    scopus 로고
    • Prostate cancer cell cycle regulators: Response to androgen withdrawal and development of androgen independence
    • Agus DB, Cordon-Cardo C, Fox W, et al. Prostate cancer cell cycle regulators: response to androgen withdrawal and development of androgen independence. J Natl Cancer Inst 1999;91:1869-76.
    • (1999) J Natl Cancer Inst , vol.91 , pp. 1869-1876
    • Agus, D.B.1    Cordon-Cardo, C.2    Fox, W.3
  • 13
    • 0032771584 scopus 로고    scopus 로고
    • Androgen and epidermal growth factor down-regulate cyclin-dependent kinase inhibitor p27Kip1 and costimulate proliferation of MDA PCa 2a and MDA PCa 2b prostate cancer cells
    • Ye D, Mendelsohn J, Fan Z. Androgen and epidermal growth factor down-regulate cyclin-dependent kinase inhibitor p27Kip1 and costimulate proliferation of MDA PCa 2a and MDA PCa 2b prostate cancer cells. Clin Cancer Res 1999;5:2171-7.
    • (1999) Clin Cancer Res , vol.5 , pp. 2171-2177
    • Ye, D.1    Mendelsohn, J.2    Fan, Z.3
  • 14
    • 17744375952 scopus 로고    scopus 로고
    • Androgen-driven prostate epithelial cell proliferation and differentiation in vivo involve the regulation of p27
    • Waltregny D, Leav I, Signoretti S, et al. Androgen-driven prostate epithelial cell proliferation and differentiation in vivo involve the regulation of p27. Mol Endocrinol 2001;15:765-82.
    • (2001) Mol Endocrinol , vol.15 , pp. 765-782
    • Waltregny, D.1    Leav, I.2    Signoretti, S.3
  • 16
    • 0032913866 scopus 로고    scopus 로고
    • Androgen regulation of the cyclin-dependent kinase inhibitor p21 gene through an androgen response element in the proximal promoter
    • Lu S, Liu M, Epner DE, Tsai SY, Tsai MJ. Androgen regulation of the cyclin-dependent kinase inhibitor p21 gene through an androgen response element in the proximal promoter. Mol Endocrinol 1999;13:376-84.
    • (1999) Mol Endocrinol , vol.13 , pp. 376-384
    • Lu, S.1    Liu, M.2    Epner, D.E.3    Tsai, S.Y.4    Tsai, M.J.5
  • 17
    • 0037936552 scopus 로고    scopus 로고
    • Androgen-stimulated DNA synthesis and cytoskeletal changes in fibroblasts by a nontranscriptional receptor action
    • Castoria G, Lombardi M, Barone MV, et al. Androgen-stimulated DNA synthesis and cytoskeletal changes in fibroblasts by a nontranscriptional receptor action. J Cell Biol 2003;161:547-56.
    • (2003) J Cell Biol , vol.161 , pp. 547-556
    • Castoria, G.1    Lombardi, M.2    Barone, M.V.3
  • 18
    • 0242290354 scopus 로고    scopus 로고
    • Activation of phosphatidylinositol 3-kinase/Akt pathway by androgen through interaction of p85α, androgen receptor, and Src
    • Sun M, Yang L, Feldman RI, et al. Activation of phosphatidylinositol 3-kinase/Akt pathway by androgen through interaction of p85α, androgen receptor, and Src. J Biol Chem 2003;278:42992-3000.
    • (2003) J Biol Chem , vol.278 , pp. 42992-43000
    • Sun, M.1    Yang, L.2    Feldman, R.I.3
  • 19
    • 2442528552 scopus 로고    scopus 로고
    • Androgen receptor mediates non-genomic activation of phosphatidylinositol 3-OH kinase in androgen-sensitive epithelial cells
    • Baron S, Manin M, Beaudoin C, et al. Androgen receptor mediates non-genomic activation of phosphatidylinositol 3-OH kinase in androgen-sensitive epithelial cells. J Biol Chem 2004;279:14579-86.
    • (2004) J Biol Chem , vol.279 , pp. 14579-14586
    • Baron, S.1    Manin, M.2    Beaudoin, C.3
  • 20
    • 0033569406 scopus 로고    scopus 로고
    • Molecular classification of cancer: Class discovery and class prediction by gene expression monitoring
    • Golub TR, Slonim DK, Tamayo P, et al. Molecular classification of cancer: class discovery and class prediction by gene expression monitoring. Science 1999;286:531-7.
    • (1999) Science , vol.286 , pp. 531-537
    • Golub, T.R.1    Slonim, D.K.2    Tamayo, P.3
  • 21
    • 0345732640 scopus 로고    scopus 로고
    • mTOR controls cell cycle progression through its cell growth effectors S6K1 and 4E-BP1/eukaryotic translation initiation factor 4E
    • Fingar DC, Richardson CJ, Tee AR, Cheatham L, Tsou C, Blenis J. mTOR controls cell cycle progression through its cell growth effectors S6K1 and 4E-BP1/eukaryotic translation initiation factor 4E. Mol Cell Biol 2004;24:200-16.
    • (2004) Mol Cell Biol , vol.24 , pp. 200-216
    • Fingar, D.C.1    Richardson, C.J.2    Tee, A.R.3    Cheatham, L.4    Tsou, C.5    Blenis, J.6
  • 22
    • 0032491579 scopus 로고    scopus 로고
    • Cyclin D expression is controlled post-transcriptionally via a phosphatidylinositol 3-kinase/Akt-dependent pathway
    • Muise-Helmericks RC, Grimes HL, Bellacosa A, Malstrom SE, Tsichlis PN, Rosen N. Cyclin D expression is controlled post-transcriptionally via a phosphatidylinositol 3-kinase/Akt-dependent pathway. J Biol Chem 1998;273:29864-72.
    • (1998) J Biol Chem , vol.273 , pp. 29864-29872
    • Muise-Helmericks, R.C.1    Grimes, H.L.2    Bellacosa, A.3    Malstrom, S.E.4    Tsichlis, P.N.5    Rosen, N.6
  • 23
    • 0035312747 scopus 로고    scopus 로고
    • Regulation of translation initiation by FRAP/mTOR
    • Gingras AC, Raught B, Sonenberg N. Regulation of translation initiation by FRAP/mTOR. Genes Dev 2001;15:807-26.
    • (2001) Genes Dev , vol.15 , pp. 807-826
    • Gingras, A.C.1    Raught, B.2    Sonenberg, N.3
  • 24
    • 1642535431 scopus 로고    scopus 로고
    • AKT activity determines sensitivity to mammalian target of rapamycin (mTOR) inhibitors by regulating cyclin D1 and c-myc expression
    • Gera JF, Mellinghoff IK, Shi Y, et al. AKT activity determines sensitivity to mammalian target of rapamycin (mTOR) inhibitors by regulating cyclin D1 and c-myc expression. J Biol Chem 2004;279:2737-46.
    • (2004) J Biol Chem , vol.279 , pp. 2737-2746
    • Gera, J.F.1    Mellinghoff, I.K.2    Shi, Y.3
  • 25
    • 2342545519 scopus 로고    scopus 로고
    • Target of rapamycin (TOR): An integrator of nutrient and growth factor signals and coordinator of cell growth and cell cycle progression
    • Fingar DC, Blenis J. Target of rapamycin (TOR): an integrator of nutrient and growth factor signals and coordinator of cell growth and cell cycle progression. Oncogene 2004;23:3151-71.
    • (2004) Oncogene , vol.23 , pp. 3151-3171
    • Fingar, D.C.1    Blenis, J.2
  • 26
    • 0036342294 scopus 로고    scopus 로고
    • Identification of the tuberous sclerosis complex-2 tumor suppressor gene product tuberin as a target of the phosphoinositide 3-kinase/Akt pathway
    • Manning BD, Tee AR, Logsdon MN, Blenis J, Cantley LC. Identification of the tuberous sclerosis complex-2 tumor suppressor gene product tuberin as a target of the phosphoinositide 3-kinase/Akt pathway. Mol Cell 2002;10:151-62.
    • (2002) Mol Cell , vol.10 , pp. 151-162
    • Manning, B.D.1    Tee, A.R.2    Logsdon, M.N.3    Blenis, J.4    Cantley, L.C.5
  • 27
    • 0036713778 scopus 로고    scopus 로고
    • TSC2 is phosphorylated and inhibited by Akt and suppresses mTOR signalling
    • Inoki K, Li Y, Zhu T, Wu J, Guan KL. TSC2 is phosphorylated and inhibited by Akt and suppresses mTOR signalling. Nat Cell Biol 2002;4:648-57.
    • (2002) Nat Cell Biol , vol.4 , pp. 648-657
    • Inoki, K.1    Li, Y.2    Zhu, T.3    Wu, J.4    Guan, K.L.5
  • 28
    • 0036714127 scopus 로고    scopus 로고
    • Akt regulates growth by directly phosphorylating Tsc2
    • Potter CJ, Pedraza LG, Xu T. Akt regulates growth by directly phosphorylating Tsc2. Nat Cell Biol 2002;4:658-65.
    • (2002) Nat Cell Biol , vol.4 , pp. 658-665
    • Potter, C.J.1    Pedraza, L.G.2    Xu, T.3
  • 29
    • 18544375193 scopus 로고    scopus 로고
    • Phosphatidylinositol 3-kinase/Akt pathway regulates tuberous sclerosis tumor suppressor complex by phosphorylation of tuberin
    • Dan HC, Sun M, Yang L, et al. Phosphatidylinositol 3-kinase/Akt pathway regulates tuberous sclerosis tumor suppressor complex by phosphorylation of tuberin. J Biol Chem 2002;277:35364-70.
    • (2002) J Biol Chem , vol.277 , pp. 35364-35370
    • Dan, H.C.1    Sun, M.2    Yang, L.3
  • 31
    • 4544384577 scopus 로고    scopus 로고
    • Tumor-promoting phorbol esters and activated Ras inactivate the tuberous sclerosis tumor suppressor complex via p90 ribosomal S6 kinase
    • Roux PP, Ballif BA, Anjum R, Gygi SP, Blenis J. Tumor-promoting phorbol esters and activated Ras inactivate the tuberous sclerosis tumor suppressor complex via p90 ribosomal S6 kinase. Proc Natl Acad Sci U S A 2004;101:13489-94.
    • (2004) Proc Natl Acad Sci U S A , vol.101 , pp. 13489-13494
    • Roux, P.P.1    Ballif, B.A.2    Anjum, R.3    Gygi, S.P.4    Blenis, J.5
  • 32
    • 0031952597 scopus 로고    scopus 로고
    • Identification of regulatory phosphorylation sites in mitogen-activated protein kinase (MAPK)-activated protein kinase-1a/p90rsk that are inducible by MAPK
    • Dalby KN, Morrice N, Caudwell FB, Avruch J, Cohen P. Identification of regulatory phosphorylation sites in mitogen-activated protein kinase (MAPK)-activated protein kinase-1a/p90rsk that are inducible by MAPK. J Biol Chem 1998;273:1496-505.
    • (1998) J Biol Chem , vol.273 , pp. 1496-1505
    • Dalby, K.N.1    Morrice, N.2    Caudwell, F.B.3    Avruch, J.4    Cohen, P.5
  • 33
    • 0345167800 scopus 로고    scopus 로고
    • TSC2 mediates cellular energy response to control cell growth and survival
    • Inoki K, Zhu T, Guan KL. TSC2 mediates cellular energy response to control cell growth and survival. Cell 2003;115:577-90.
    • (2003) Cell , vol.115 , pp. 577-590
    • Inoki, K.1    Zhu, T.2    Guan, K.L.3
  • 34
    • 0035488295 scopus 로고    scopus 로고
    • Identification of androgen-regulated genes in the prostate cancer cell line LNCaP by serial analysis of gene expression and proteomic analysis
    • Waghray A, Feroze F, Schober MS, et al. Identification of androgen-regulated genes in the prostate cancer cell line LNCaP by serial analysis of gene expression and proteomic analysis. Proteomics 2001;1:1327-38.
    • (2001) Proteomics , vol.1 , pp. 1327-1338
    • Waghray, A.1    Feroze, F.2    Schober, M.S.3
  • 35
    • 0037015040 scopus 로고    scopus 로고
    • The program of androgen-responsive genes in neoplastic prostate epithelium
    • Nelson PS, Clegg N, Arnold H, et al. The program of androgen-responsive genes in neoplastic prostate epithelium. Proc Natl Acad Sci U S A 2002;99:11890-5.
    • (2002) Proc Natl Acad Sci U S A , vol.99 , pp. 11890-11895
    • Nelson, P.S.1    Clegg, N.2    Arnold, H.3
  • 36
    • 17144444034 scopus 로고    scopus 로고
    • Transcriptional programs activated by exposure of human prostate cancer cells to androgen
    • RESEARCH0032
    • Deprimo SE, Diehn M, Nelson JB, et al. Transcriptional programs activated by exposure of human prostate cancer cells to androgen. Genome Biol 2002;3:RESEARCH0032.
    • (2002) Genome Biol , vol.3
    • Deprimo, S.E.1    Diehn, M.2    Nelson, J.B.3
  • 37
    • 0037069941 scopus 로고    scopus 로고
    • Androgen-induced expression of endoplasmic reticulum (ER) stress response genes in prostate cancer cells
    • Segawa T, Nau ME, Xu LL, et al. Androgen-induced expression of endoplasmic reticulum (ER) stress response genes in prostate cancer cells. Oncogene 2002;21:8749-58.
    • (2002) Oncogene , vol.21 , pp. 8749-8758
    • Segawa, T.1    Nau, M.E.2    Xu, L.L.3
  • 38
    • 3843091606 scopus 로고    scopus 로고
    • Identification and validation of novel androgen-regulated genes in prostate cancer
    • Velasco AM, Gillis KA, Li Y, et al. Identification and validation of novel androgen-regulated genes in prostate cancer. Endocrinology 2004;145:3913-24.
    • (2004) Endocrinology , vol.145 , pp. 3913-3924
    • Velasco, A.M.1    Gillis, K.A.2    Li, Y.3
  • 39
    • 17144370286 scopus 로고    scopus 로고
    • Androgen mediated regulation and functional implications of fkbp51 expression in prostate cancer
    • Febbo PG, Lowenberg M, Thorner AR, Brown M, Loda M, Golub TR. Androgen mediated regulation and functional implications of fkbp51 expression in prostate cancer. J Urol 2005;173:1772-7.
    • (2005) J Urol , vol.173 , pp. 1772-1777
    • Febbo, P.G.1    Lowenberg, M.2    Thorner, A.R.3    Brown, M.4    Loda, M.5    Golub, T.R.6
  • 40
    • 0027535976 scopus 로고
    • High-affinity L-aspartate transporter in prostate epithelial cells that is regulated by testosterone
    • Lao L, Franklin RB, Costello LC. High-affinity L-aspartate transporter in prostate epithelial cells that is regulated by testosterone. Prostate 1993;22:53-63.
    • (1993) Prostate , vol.22 , pp. 53-63
    • Lao, L.1    Franklin, R.B.2    Costello, L.C.3
  • 41
    • 14644417204 scopus 로고    scopus 로고
    • Transport regulation by the serum- and glucocorticoid-inducible kinase SGK1
    • Lang F, Vallon V, Grahammer F, Palmada M, Bohmer C. Transport regulation by the serum- and glucocorticoid-inducible kinase SGK1. Biochem Soc Trans 2005;33:213-5.
    • (2005) Biochem Soc Trans , vol.33 , pp. 213-215
    • Lang, F.1    Vallon, V.2    Grahammer, F.3    Palmada, M.4    Bohmer, C.5
  • 43
    • 0028921940 scopus 로고
    • Triiodothyronine modulates growth, secretory function and androgen receptor concentration in the prostatic carcinoma cell line LNCaP
    • Esquenet M, Swinnen JV, Heyns W, Verhoeven G. Triiodothyronine modulates growth, secretory function and androgen receptor concentration in the prostatic carcinoma cell line LNCaP. Mol Cell Endocrinol 1995;109:105-11.
    • (1995) Mol Cell Endocrinol , vol.109 , pp. 105-111
    • Esquenet, M.1    Swinnen, J.V.2    Heyns, W.3    Verhoeven, G.4
  • 44
    • 0032982444 scopus 로고    scopus 로고
    • Interactive effects of triiodothyronine and androgens on prostate cell growth and gene expression
    • Zhang S, Hsieh ML, Zhu W, Klee GG, Tindall DJ, Young CY. Interactive effects of triiodothyronine and androgens on prostate cell growth and gene expression. Endocrinology 1999;140:1665-71.
    • (1999) Endocrinology , vol.140 , pp. 1665-1671
    • Zhang, S.1    Hsieh, M.L.2    Zhu, W.3    Klee, G.G.4    Tindall, D.J.5    Young, C.Y.6
  • 45
    • 0033570240 scopus 로고    scopus 로고
    • Propylthiouracil-induced hypothyroidism reduces xenograft tumor growth in athymic nude mice
    • Theodossiou C, Skrepnik N, Robert EG, et al. Propylthiouracil-induced hypothyroidism reduces xenograft tumor growth in athymic nude mice. Cancer 1999;86:1596-601.
    • (1999) Cancer , vol.86 , pp. 1596-1601
    • Theodossiou, C.1    Skrepnik, N.2    Robert, E.G.3
  • 46
    • 22144499549 scopus 로고    scopus 로고
    • The Hedgehog-inducible ubiquitin ligase subunit WSB-1 modulates thyroid hormone activation and PTHrP secretion in the developing growth plate
    • Dentice M, Bandyopadhyay A, Gereben B, et al. The Hedgehog-inducible ubiquitin ligase subunit WSB-1 modulates thyroid hormone activation and PTHrP secretion in the developing growth plate. Nat Cell Biol 2005;7:698-705.
    • (2005) Nat Cell Biol , vol.7 , pp. 698-705
    • Dentice, M.1    Bandyopadhyay, A.2    Gereben, B.3
  • 47
    • 21244456553 scopus 로고    scopus 로고
    • Rheb binding to mammalian target of rapamycin (mTOR) is regulated by amino acid sufficiency
    • Long X, Ortiz-Vega S, Lin Y, Avruch J. Rheb binding to mammalian target of rapamycin (mTOR) is regulated by amino acid sufficiency. J Biol Chem 2005;280:23433-6.
    • (2005) J Biol Chem , vol.280 , pp. 23433-23436
    • Long, X.1    Ortiz-Vega, S.2    Lin, Y.3    Avruch, J.4
  • 48
    • 0028944970 scopus 로고
    • Regulation of proliferation and production of prostate-specific antigen in androgen-sensitive prostatic cancer cells, LNCaP, by dihydrotestosterone
    • Lee C, Sutkowski DM, Sensibar JA, et al. Regulation of proliferation and production of prostate-specific antigen in androgen-sensitive prostatic cancer cells, LNCaP, by dihydrotestosterone. Endocrinology 1995;136:796-803.
    • (1995) Endocrinology , vol.136 , pp. 796-803
    • Lee, C.1    Sutkowski, D.M.2    Sensibar, J.A.3
  • 49
    • 0029671462 scopus 로고    scopus 로고
    • Transforming growth factor β1 is a mediator of androgen-regulated growth arrest in an androgen-responsive prostatic cancer cell line, LNCaP
    • Kim IY, Kim JH, Zelner DJ, Ahn HJ, Sensibar JA, Lee C. Transforming growth factor β1 is a mediator of androgen-regulated growth arrest in an androgen-responsive prostatic cancer cell line, LNCaP. Endocrinology 1996;137:991-9.
    • (1996) Endocrinology , vol.137 , pp. 991-999
    • Kim, I.Y.1    Kim, J.H.2    Zelner, D.J.3    Ahn, H.J.4    Sensibar, J.A.5    Lee, C.6
  • 50
    • 1842584190 scopus 로고    scopus 로고
    • Steroids and oocyte maturation-a new look at an old story
    • Hammes SR. Steroids and oocyte maturation-a new look at an old story. Mol Endocrinol 2004;18:769-75.
    • (2004) Mol Endocrinol , vol.18 , pp. 769-775
    • Hammes, S.1
  • 51
    • 0035496220 scopus 로고    scopus 로고
    • The development of androgen-independent prostate cancer
    • Feldman BJ, Feldman D. The development of androgen-independent prostate cancer. Nat Rev Cancer 2001;1:34-45.
    • (2001) Nat Rev Cancer , vol.1 , pp. 34-45
    • Feldman, B.J.1    Feldman, D.2
  • 52
    • 0036755404 scopus 로고    scopus 로고
    • Androgen receptor as a target in androgen-independent prostate cancer
    • Balk SP. Androgen receptor as a target in androgen-independent prostate cancer. Urology 2002;60:132-8.
    • (2002) Urology , vol.60 , pp. 132-138
    • Balk, S.P.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.