Activated Cdc42-associated kinase Ack1 promotes prostate cancer progression via androgen receptor tyrosine phosphorylation

Proceedings of the National Academy of Sciences of the United States of America

Volumn 104, Issue 20, 2007, Pages 8438-8443

  Mahajan, Nupam P ^a   Liu, Yuanbo ^a   Majumder, Samarpan ^a   Warren, Maria R ^a   Parker, Carol E ^a   Mohler, James L ^a   Earp, H Shelton ^a   Whang, Young E ^a,b  

^a UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

^b ROSWELL PARK CANCER INSTITUTE   (United States)

Author keywords

Ack1 tyrosine kinase; Cross talk; HER2; Signal transduction

Indexed keywords

ANDROGEN RECEPTOR; EPIDERMAL GROWTH FACTOR RECEPTOR 2; NEU DIFFERENTIATION FACTOR; PROTEIN ACK1; PROTEIN KINASE; UNCLASSIFIED DRUG; ACK1 PROTEIN, HUMAN; ANDROGEN; AR PROTEIN, HUMAN; DNA; PHOSPHOTYROSINE; PROTEIN TYROSINE KINASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL STRAIN LNCAP; CHROMATIN IMMUNOPRECIPITATION; CONTROLLED STUDY; GENE EXPRESSION; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOBLOTTING; IMMUNOPRECIPITATION; MOUSE; NONHUMAN; POINT MUTATION; PRIORITY JOURNAL; PROSTATE CANCER; PROTEIN DOMAIN; PROTEIN PHOSPHORYLATION; TUMOR XENOGRAFT; ANIMAL; BIOLOGICAL MODEL; CHEMISTRY; DISEASE COURSE; DRUG EFFECT; ENHANCER REGION; ENZYME ACTIVATION; GENE EXPRESSION REGULATION; GENETIC TRANSCRIPTION; GENETICS; MALE; METABOLISM; MUTATION; PATHOLOGY; PHOSPHORYLATION; PROSTATE TUMOR; PROTEIN BINDING; PROTEIN TRANSPORT; TUMOR CELL LINE; XENOGRAFT;

ANDROGENS; ANIMALS; CELL LINE, TUMOR; DISEASE PROGRESSION; DNA, NEOPLASM; ENHANCER ELEMENTS (GENETICS); ENZYME ACTIVATION; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; MALE; MICE; MODELS, GENETIC; MUTATION; NEUREGULIN-1; PHOSPHORYLATION; PHOSPHOTYROSINE; PROSTATIC NEOPLASMS; PROTEIN BINDING; PROTEIN TRANSPORT; PROTEIN-TYROSINE KINASES; RECEPTOR, ERBB-2; RECEPTORS, ANDROGEN; TRANSCRIPTION, GENETIC; TRANSPLANTATION, HETEROLOGOUS;

EID: 34347263425     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.0700420104     Document Type: Article

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