Androgen receptor splice variants activate androgen receptor target genes and support aberrant prostate cancer cell growth independent of canonical androgen receptor nuclear localization signal

Journal of Biological Chemistry

Volumn 287, Issue 23, 2012, Pages 19736-19749

  Chan, Siu Chiu ^a   Li, Yingming ^a   Dehm, Scott M ^a,b  

^a UNIVERSITY OF MINNESOTA   (United States)

^b UNIVERSITY OF MINNESOTA MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANDROGEN RECEPTORS; BASAL LEVELS; COOH-TERMINAL; DNA BINDING DOMAIN; LOCALIZATION PATTERNS; NUCLEAR IMPORT; NUCLEAR LOCALIZATION; NUCLEAR LOCALIZATION SIGNAL; NUCLEAR TRANSLOCATIONS; PROSTATE CANCER CELLS; PROSTATE CANCERS; PROTEIN DOMAINS; SPLICE VARIANTS; TARGET GENES; TERMINAL DOMAIN; TRANSCRIPTIONAL ACTIVATIONS; TRANSCRIPTIONAL ACTIVITY;

GENES; LIGANDS;

DISEASES;

ANDROGEN; ANDROGEN RECEPTOR; HEAT SHOCK PROTEIN 90; KARYOPHERIN BETA; LIGAND; PROTEIN VARIANT; TRANSCRIPTION FACTOR;

AMINO TERMINAL SEQUENCE; ARTICLE; CANCER GROWTH; CARBOXY TERMINAL SEQUENCE; CELL NUCLEUS; CONTROLLED STUDY; CYTOPLASM; GENE TARGETING; GENETIC VARIABILITY; INTRACELLULAR TRANSPORT; NUCLEAR IMPORT; NUCLEAR LOCALIZATION SIGNAL; PRIORITY JOURNAL; PROSTATE CANCER; PROTEIN DNA BINDING; PROTEIN DOMAIN; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN TRANSPORT; RNA SPLICING; TRANSCRIPTION INITIATION;

ACTIVE TRANSPORT, CELL NUCLEUS; ALTERNATIVE SPLICING; ANIMALS; BETA KARYOPHERINS; CELL NUCLEUS; CERCOPITHECUS AETHIOPS; COS CELLS; HSP90 HEAT-SHOCK PROTEINS; HUMANS; MALE; NEOPLASM PROTEINS; NUCLEAR LOCALIZATION SIGNALS; PROSTATIC NEOPLASMS; RECEPTORS, ANDROGEN; TRANSCRIPTION, GENETIC;

EID: 84861728843     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.352930     Document Type: Article

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