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Volumn 120, Issue 12, 2010, Pages 4478-4492

The retinoblastoma tumor suppressor controls androgen signaling and human prostate cancer progression

Author keywords

[No Author keywords available]

Indexed keywords

ANDROGEN; ANDROGEN RECEPTOR; RETINOBLASTOMA PROTEIN; TRANSCRIPTION FACTOR E2F1;

EID: 78649888666     PISSN: 00219738     EISSN: 15588238     Source Type: Journal    
DOI: 10.1172/JCI44239     Document Type: Article
Times cited : (262)

References (57)
  • 1
    • 50149120366 scopus 로고    scopus 로고
    • Cellular mechanisms of tumour suppression by the retinoblastoma gene
    • Burkhart DL, Sage J. Cellular mechanisms of tumour suppression by the retinoblastoma gene. Nat Rev Cancer. 2008;8(9):671-682.
    • (2008) Nat Rev Cancer , vol.8 , Issue.9 , pp. 671-682
    • Burkhart, D.L.1    Sage, J.2
  • 2
    • 0031862730 scopus 로고    scopus 로고
    • Growth suppression by an E2F-binding defective retinoblastoma protein (RB): Contribution from the RB C pocket
    • Whitaker LL, Su H, Baskaran R, Knudsen ES, Wang JY. Growth suppression by an E2F-binding-defective retinoblastoma protein (RB): contribution from the RB C pocket. Mol Cell Biol. 1998;18(7):4032-4042. (Pubitemid 28287927)
    • (1998) Molecular and Cellular Biology , vol.18 , Issue.7 , pp. 4032-4042
    • Whitaker, L.L.1    Su, H.2    Baskaran, R.3    Knudsen, E.S.4    Wang, J.Y.J.5
  • 3
    • 50149084928 scopus 로고    scopus 로고
    • Tailoring to RB: Tumour suppressor status and therapeutic response
    • Knudsen ES, Knudsen KE. Tailoring to RB: tumour suppressor status and therapeutic response. Nat Rev Cancer. 2008;8(9):714-724.
    • (2008) Nat Rev Cancer , vol.8 , Issue.9 , pp. 714-724
    • Knudsen, E.S.1    Knudsen, K.E.2
  • 4
    • 0021914111 scopus 로고
    • Genetic origin of mutations predisposing to retinoblastoma
    • Cavenee WK, et al. Genetic origin of mutations predisposing to retinoblastoma. Science. 1985;228(4698):501-503.
    • (1985) Science , vol.228 , Issue.4698 , pp. 501-503
    • Cavenee, W.K.1
  • 5
    • 0035754080 scopus 로고    scopus 로고
    • To cycle or not to cycle: A critical decision in cancer
    • Malumbres M, Barbacid M. To cycle or not to cycle: a critical decision in cancer. Nat Rev Cancer. 2001;1(3):222-231. (Pubitemid 33741897)
    • (2001) Nature Reviews Cancer , vol.1 , Issue.3 , pp. 222-231
    • Malumbres, M.1    Barbacid, M.2
  • 6
    • 33644675811 scopus 로고    scopus 로고
    • Biology of progressive, castration- resistant prostate cancer: Directed therapies targeting the androgen-receptor signaling axis
    • Scher HI, Sawyers CL. Biology of progressive, castration- resistant prostate cancer: directed therapies targeting the androgen-receptor signaling axis. J Clin Oncol. 2005;23(32):8253-8261.
    • (2005) J Clin Oncol , vol.23 , Issue.32 , pp. 8253-8261
    • Scher, H.I.1    Sawyers, C.L.2
  • 7
    • 68049140791 scopus 로고    scopus 로고
    • Starving the addiction: New opportunities for durable suppression of AR signaling in prostate cancer
    • Knudsen KE, Scher HI. Starving the addiction: new opportunities for durable suppression of AR signaling in prostate cancer. Clin Cancer Res. 2009;15(15):4792-4798.
    • (2009) Clin Cancer Res , vol.15 , Issue.15 , pp. 4792-4798
    • Knudsen, K.E.1    Scher, H.I.2
  • 8
    • 34447121974 scopus 로고    scopus 로고
    • Retinoblastoma tumor suppressor status is a critical determinant of therapeutic response in prostate cancer cells
    • Sharma A, et al. Retinoblastoma tumor suppressor status is a critical determinant of therapeutic response in prostate cancer cells. Cancer Res. 2007;67(13):6192-6203.
    • (2007) Cancer Res , vol.67 , Issue.13 , pp. 6192-6203
    • Sharma, A.1
  • 9
    • 0037112450 scopus 로고    scopus 로고
    • Unbiased analysis of RB-mediated transcriptional repression identifies novel targets and distinctions from E2F action
    • Markey MP, et al. Unbiased analysis of RB-mediated transcriptional repression identifies novel targets and distinctions from E2F action. Cancer Res. 2002;62(22):6587-6597.
    • (2002) Cancer Res , vol.62 , Issue.22 , pp. 6587-6597
    • Markey, M.P.1
  • 10
    • 33845972969 scopus 로고    scopus 로고
    • The retinoblastoma tumor suppressor modifies the therapeutic response of breast cancer
    • Bosco EE, et al. The retinoblastoma tumor suppressor modifies the therapeutic response of breast cancer. J Clin Invest. 2007;117(1):218-228.
    • (2007) J Clin Invest , vol.117 , Issue.1 , pp. 218-228
    • Bosco, E.E.1
  • 11
    • 34548483149 scopus 로고    scopus 로고
    • RB loss abrogates cell cycle control and genome integrity to promote liver tumorigenesis
    • Mayhew CN, et al. RB loss abrogates cell cycle control and genome integrity to promote liver tumorigenesis. Gastroenterology. 2007;133(3):976-984.
    • (2007) Gastroenterology , vol.133 , Issue.3 , pp. 976-984
    • Mayhew, C.N.1
  • 12
    • 34648840189 scopus 로고    scopus 로고
    • Loss of the retinoblastoma tumor suppressor: Differential action on transcriptional programs related to cell cycle control and immune function
    • Markey MP, et al. Loss of the retinoblastoma tumor suppressor: differential action on transcriptional programs related to cell cycle control and immune function. Oncogene. 2007;26(43):6307-6318.
    • (2007) Oncogene , vol.26 , Issue.43 , pp. 6307-6318
    • Markey, M.P.1
  • 13
    • 77955296562 scopus 로고    scopus 로고
    • Castration resistance in human prostate cancer is conferred by a frequently occurring androgen receptor splice variant
    • Sun S, et al. Castration resistance in human prostate cancer is conferred by a frequently occurring androgen receptor splice variant. J Clin Invest. 2010;120(8):2715-2730.
    • (2010) J Clin Invest , vol.120 , Issue.8 , pp. 2715-2730
    • Sun, S.1
  • 14
    • 33750366075 scopus 로고    scopus 로고
    • Persistent prostate-specific antigen expression after neoadjuvant androgen depletion: An early predictor of relapse or incomplete androgen suppression
    • Ryan CJ, et al. Persistent prostate-specific antigen expression after neoadjuvant androgen depletion: an early predictor of relapse or incomplete androgen suppression. Urology. 2006;68(4):834-839.
    • (2006) Urology , vol.68 , Issue.4 , pp. 834-839
    • Ryan, C.J.1
  • 15
    • 67650758019 scopus 로고    scopus 로고
    • Androgen receptor regulates a distinct transcription program in androgen-independent prostate cancer
    • Wang Q, et al. Androgen receptor regulates a distinct transcription program in androgen-independent prostate cancer. Cell. 2009;138(2):245-256.
    • (2009) Cell , vol.138 , Issue.2 , pp. 245-256
    • Wang, Q.1
  • 16
    • 0036208492 scopus 로고    scopus 로고
    • Formation of the androgen receptor transcription complex
    • DOI 10.1016/S1097-2765(02)00471-9
    • Shang Y, Myers M, Brown M. Formation of the androgen receptor transcription complex. Mol Cell. 2002;9(3):601-610. (Pubitemid 34273790)
    • (2002) Molecular Cell , vol.9 , Issue.3 , pp. 601-610
    • Shang, Y.1    Myers, M.2    Brown, M.3
  • 17
    • 33751550697 scopus 로고    scopus 로고
    • Stimulation of steroid receptor coactivator-3 (SRC-3) gene overexpression by a positive regulatory loop of E2F1 and SRC-3
    • DOI 10.1210/me.2005-0522
    • Mussi P, Yu C, O'Malley BW, Xu J. Stimulation of steroid receptor coactivator-3 (SRC-3) gene overexpression by a positive regulatory loop of E2F1 and SRC-3. Mol Endocrinol. 2006;20(12):3105-3119. (Pubitemid 44833559)
    • (2006) Molecular Endocrinology , vol.20 , Issue.12 , pp. 3105-3119
    • Mussi, P.1    Yu, C.2    O'Malley, B.W.3    Xu, J.4
  • 18
    • 55549103719 scopus 로고    scopus 로고
    • E2F in vivo binding specificity: Comparison of consensus versus nonconsensus binding sites
    • Rabinovich A, Jin VX, Rabinovich R, Xu X, Farnham PJ. E2F in vivo binding specificity: comparison of consensus versus nonconsensus binding sites. Genome Res. 2008;18(11):1763-1777.
    • (2008) Genome Res , vol.18 , Issue.11 , pp. 1763-1777
    • Rabinovich, A.1    Jin, V.X.2    Rabinovich, R.3    Xu, X.4    Farnham, P.J.5
  • 19
    • 70350518233 scopus 로고    scopus 로고
    • Emerging roles of E2Fs in cancer: An exit from cell cycle control
    • Chen HZ, Tsai SY, Leone G. Emerging roles of E2Fs in cancer: an exit from cell cycle control. Nat Rev Cancer. 2009;9(11):785-797.
    • (2009) Nat Rev Cancer , vol.9 , Issue.11 , pp. 785-797
    • Chen, H.Z.1    Tsai, S.Y.2    Leone, G.3
  • 20
    • 0029612231 scopus 로고
    • A potent transrepression domain in the retinoblastoma protein induces a cell cycle arrest when bound to E2F sites
    • Sellers WR, Rodgers JW, Kaelin WG Jr. A potent transrepression domain in the retinoblastoma protein induces a cell cycle arrest when bound to E2F sites. Proc Natl Acad Sci U S A. 1995;92(25):11544-11548.
    • (1995) Proc Natl Acad Sci U S A , vol.92 , Issue.25 , pp. 11544-11548
    • Sellers, W.R.1    Rodgers, J.W.2    Kaelin Jr., W.G.3
  • 21
    • 49249119358 scopus 로고    scopus 로고
    • Maintenance of intratumoral androgens in metastatic prostate cancer: A mechanism for castration-resistant tumor growth
    • Montgomery RB, et al. Maintenance of intratumoral androgens in metastatic prostate cancer: a mechanism for castration-resistant tumor growth. Cancer Res. 2008;68(11):4447-4454.
    • (2008) Cancer Res , vol.68 , Issue.11 , pp. 4447-4454
    • Montgomery, R.B.1
  • 22
    • 0028944138 scopus 로고
    • In vivo amplification of the androgen receptor gene and progression of human prostate cancer
    • Visakorpi T, et al. In vivo amplification of the androgen receptor gene and progression of human prostate cancer. Nat Genet. 1995;9(4):401-406.
    • (1995) Nat Genet , vol.9 , Issue.4 , pp. 401-406
    • Visakorpi, T.1
  • 23
    • 1842612441 scopus 로고    scopus 로고
    • Molecular determinants of resistance to antiandrogen therapy
    • Chen CD, et al. Molecular determinants of resistance to antiandrogen therapy. Nat Med. 2004;10(1):33-39.
    • (2004) Nat Med , vol.10 , Issue.1 , pp. 33-39
    • Chen, C.D.1
  • 24
    • 76149107169 scopus 로고    scopus 로고
    • Androgen receptor expression is associated with prostate cancer-specific survival in castrate patients with metastatic disease
    • Donovan MJ, et al. Androgen receptor expression is associated with prostate cancer-specific survival in castrate patients with metastatic disease. BJU Int. 2010;105(4):462-467.
    • (2010) BJU Int , vol.105 , Issue.4 , pp. 462-467
    • Donovan, M.J.1
  • 25
    • 77954255681 scopus 로고    scopus 로고
    • Integrative genomic profiling of human prostate cancer
    • Taylor BS, et al. Integrative genomic profiling of human prostate cancer. Cancer Cell. 2010;18(1):11-22.
    • (2010) Cancer Cell , vol.18 , Issue.1 , pp. 11-22
    • Taylor, B.S.1
  • 26
    • 67449158993 scopus 로고    scopus 로고
    • Androgen receptor expression in prostate cancer cells is suppressed by activation of epidermal growth factor receptor and ErbB2
    • Cai C, Portnoy DC, Wang H, Jiang X, Chen S, Balk SP. Androgen receptor expression in prostate cancer cells is suppressed by activation of epidermal growth factor receptor and ErbB2. Cancer Res. 2009;69(12):5202-5209.
    • (2009) Cancer Res , vol.69 , Issue.12 , pp. 5202-5209
    • Cai, C.1    Portnoy, D.C.2    Wang, H.3    Jiang, X.4    Chen, S.5    Balk, S.P.6
  • 27
    • 42349084869 scopus 로고    scopus 로고
    • Androgen receptor overexpression in prostate cancer linked to Pur alpha loss from a novel repressor complex
    • Wang LG, et al. Androgen receptor overexpression in prostate cancer linked to Pur alpha loss from a novel repressor complex. Cancer Res. 2008;68(8):2678-2688.
    • (2008) Cancer Res , vol.68 , Issue.8 , pp. 2678-2688
    • Wang, L.G.1
  • 28
    • 0033305556 scopus 로고    scopus 로고
    • Differential posttranscriptional regulation of androgen receptor gene expression by androgen in prostate and breast cancer cells
    • Yeap BB, Krueger RG, Leedman PJ. Differential posttranscriptional regulation of androgen receptor gene expression by androgen in prostate and breast cancer cells. Endocrinology. 1999;140(7):3282-3291.
    • (1999) Endocrinology , vol.140 , Issue.7 , pp. 3282-3291
    • Yeap, B.B.1    Krueger, R.G.2    Leedman, P.J.3
  • 29
    • 0025982059 scopus 로고
    • Androgen increases androgen receptor protein while decreasing receptor mRNA in LNCaP cells
    • Krongrad A, Wilson CM, Wilson JD, Allman DR, McPhaul MJ. Androgen increases androgen receptor protein while decreasing receptor mRNA in LNCaP cells. Mol Cell Endocrinol. 1991;76(1-3):79-88.
    • (1991) Mol Cell Endocrinol , vol.76 , Issue.1-3 , pp. 79-88
    • Krongrad, A.1    Wilson, C.M.2    Wilson, J.D.3    Allman, D.R.4    McPhaul, M.J.5
  • 30
    • 0030954484 scopus 로고    scopus 로고
    • Transcriptional up-regulation of the human androgen receptor by androgen in bone cells
    • Wiren KM, Zhang X, Chang C, Keenan E, Orwoll ES. Transcriptional up-regulation of the human androgen receptor by androgen in bone cells. Endocrinology. 1997;138(6):2291-2300.
    • (1997) Endocrinology , vol.138 , Issue.6 , pp. 2291-2300
    • Wiren, K.M.1    Zhang, X.2    Chang, C.3    Keenan, E.4    Orwoll, E.S.5
  • 31
    • 0028107468 scopus 로고
    • Identification of 3′,5′-cyclic adenosine monophosphate response element and other cis-acting elements in the human androgen receptor gene promoter
    • Mizokami A, Yeh SY, Chang C. Identification of 3′,5′-cyclic adenosine monophosphate response element and other cis-acting elements in the human androgen receptor gene promoter. Mol Endocrinol. 1994;8(1):77-88. (Pubitemid 24985670)
    • (1994) Molecular Endocrinology , vol.8 , Issue.1 , pp. 77-88
    • Mizokami, A.1    Yeh, S.-Y.2    Chang, C.3
  • 32
    • 74449089780 scopus 로고    scopus 로고
    • Castration resistance of prostate cancer cells caused by castration-induced oxidative stress through Twist1 and androgen receptor overexpression
    • Shiota M, et al. Castration resistance of prostate cancer cells caused by castration-induced oxidative stress through Twist1 and androgen receptor overexpression. Oncogene. 2010;29(2):237-250.
    • (2010) Oncogene , vol.29 , Issue.2 , pp. 237-250
    • Shiota, M.1
  • 33
    • 68449103870 scopus 로고    scopus 로고
    • NF-kappaB regulates androgen receptor expression and prostate cancer growth
    • Zhang L, et al. NF-kappaB regulates androgen receptor expression and prostate cancer growth. Am J Pathol. 2009;175(2):489-499.
    • (2009) Am J Pathol , vol.175 , Issue.2 , pp. 489-499
    • Zhang, L.1
  • 34
    • 0027238681 scopus 로고
    • Two different, overlapping pathways of transcription initiation are active on the TATA-less human androgen receptor promoter. The role of Sp1
    • Faber PW, van Rooij HC, Schipper HJ, Brinkmann AO, Trapman J. Two different, overlapping pathways of transcription initiation are active on the TATA-less human androgen receptor promoter. The role of Sp1. J Biol Chem. 1993;268(13):9296-9301.
    • (1993) J Biol Chem , vol.268 , Issue.13 , pp. 9296-9301
    • Faber, P.W.1    Van Rooij, H.C.2    Schipper, H.J.3    Brinkmann, A.O.4    Trapman, J.5
  • 35
    • 0029769523 scopus 로고    scopus 로고
    • The retinoblastoma gene product (Rb) induces binding of a conformationally inactive nuclear factor-kappaB
    • Tamami M, Lindholm PF, Brady JN. The retinoblastoma gene product (Rb) induces binding of a conformationally inactive nuclear factor-kappaB. J Biol Chem. 1996;271(40):24551-24556.
    • (1996) J Biol Chem , vol.271 , Issue.40 , pp. 24551-24556
    • Tamami, M.1    Lindholm, P.F.2    Brady, J.N.3
  • 36
    • 65549146911 scopus 로고    scopus 로고
    • E2F1 Induces tumor cell survival via nuclear factor-kappaB-dependent induction of EGR1 transcription in prostate cancer cells
    • Zheng C, et al. E2F1 Induces tumor cell survival via nuclear factor-kappaB-dependent induction of EGR1 transcription in prostate cancer cells. Cancer Res. 2009;69(6):2324-2331.
    • (2009) Cancer Res , vol.69 , Issue.6 , pp. 2324-2331
    • Zheng, C.1
  • 37
    • 34249781210 scopus 로고    scopus 로고
    • Unique requirement for Rb/E2F3 in neuronal migration: Evidence for cell cycle-independent functions
    • McClellan KA, et al. Unique requirement for Rb/E2F3 in neuronal migration: evidence for cell cycle-independent functions. Mol Cell Biol. 2007;27(13):4825-4843.
    • (2007) Mol Cell Biol , vol.27 , Issue.13 , pp. 4825-4843
    • McClellan, K.A.1
  • 38
    • 20444453337 scopus 로고    scopus 로고
    • Up-regulation of TWIST in prostate cancer and its implication as a therapeutic target
    • Kwok WK, et al. Up-regulation of TWIST in prostate cancer and its implication as a therapeutic target. Cancer Res. 2005;65(12):5153-5162.
    • (2005) Cancer Res , vol.65 , Issue.12 , pp. 5153-5162
    • Kwok, W.K.1
  • 39
    • 0029981560 scopus 로고    scopus 로고
    • Cell cycle-regulated association of E2F1 and Sp1 is related to their functional interaction
    • Lin SY, Black AR, Kostic D, Pajovic S, Hoover CN, Azizkhan JC. Cell cycle-regulated association of E2F1 and Sp1 is related to their functional interaction. Mol Cell Biol. 1996;16(4):1668-1675.
    • (1996) Mol Cell Biol , vol.16 , Issue.4 , pp. 1668-1675
    • Lin, S.Y.1    Black, A.R.2    Kostic, D.3    Pajovic, S.4    Hoover, C.N.5    Azizkhan, J.C.6
  • 41
    • 33846244227 scopus 로고    scopus 로고
    • Elevated E2F1 inhibits transcription of the androgen receptor in metastatic hormone-resistant prostate cancer
    • Davis JN, et al. Elevated E2F1 inhibits transcription of the androgen receptor in metastatic hormone-resistant prostate cancer. Cancer Res. 2006;66(24):11897-11906.
    • (2006) Cancer Res , vol.66 , Issue.24 , pp. 11897-11906
    • Davis, J.N.1
  • 43
    • 29344474660 scopus 로고    scopus 로고
    • E2F1 expression in LNCaP prostate cancer cells deregulates androgen dependent growth, suppresses differentiation, and enhances apoptosis
    • Libertini SJ, Tepper CG, Guadalupe M, Lu Y, Asmuth DM, Mudryj M. E2F1 expression in LNCaP prostate cancer cells deregulates androgen dependent growth, suppresses differentiation, and enhances apoptosis. Prostate. 2006;66(1):70-81.
    • (2006) Prostate , vol.66 , Issue.1 , pp. 70-81
    • Libertini, S.J.1    Tepper, C.G.2    Guadalupe, M.3    Lu, Y.4    Asmuth, D.M.5    Mudryj, M.6
  • 44
    • 0032493489 scopus 로고    scopus 로고
    • Multiple G1 regulatory elements control the androgen-dependent proliferation of prostatic carcinoma cells
    • Knudsen KE, Arden KC, Cavenee WK. Multiple G1 regulatory elements control the androgen-dependent proliferation of prostatic carcinoma cells. J Biol Chem. 1998;273(32):20213-20222.
    • (1998) J Biol Chem , vol.273 , Issue.32 , pp. 20213-20222
    • Knudsen, K.E.1    Arden, K.C.2    Cavenee, W.K.3
  • 45
    • 74649085093 scopus 로고    scopus 로고
    • Transcription factor E2F1 is a potent transactivator of the insulin-like growth factor-I receptor (IGF-IR) gene
    • Schayek H, et al. Transcription factor E2F1 is a potent transactivator of the insulin-like growth factor-I receptor (IGF-IR) gene. Growth Horm IGF Res. 2010;20(1):68-72.
    • (2010) Growth Horm IGF Res , vol.20 , Issue.1 , pp. 68-72
    • Schayek, H.1
  • 46
    • 12844285560 scopus 로고    scopus 로고
    • Transcriptional networks and cellular senescence in human mammary fibroblasts
    • Hardy K, et al. Transcriptional networks and cellular senescence in human mammary fibroblasts. Mol Biol Cell. 2005;16(2):943-953.
    • (2005) Mol Biol Cell , vol.16 , Issue.2 , pp. 943-953
    • Hardy, K.1
  • 47
    • 34548336347 scopus 로고    scopus 로고
    • Estrogen-regulated gene networks in human breast cancer cells: Involvement of E2F1 in the regulation of cell proliferation
    • Stender JD, Frasor J, Komm B, Chang KC, Kraus WL, Katzenellenbogen BS. Estrogen-regulated gene networks in human breast cancer cells: involvement of E2F1 in the regulation of cell proliferation. Mol Endocrinol. 2007;21(9):2112-2123.
    • (2007) Mol Endocrinol , vol.21 , Issue.9 , pp. 2112-2123
    • Stender, J.D.1    Frasor, J.2    Komm, B.3    Chang, K.C.4    Kraus, W.L.5    Katzenellenbogen, B.S.6
  • 48
    • 34548029170 scopus 로고    scopus 로고
    • Involvement of the CDK2-E2F1 pathway in cisplatin cytotoxicity in vitro and in vivo
    • Yu F, Megyesi J, Safirstein RL, Price PM. Involvement of the CDK2-E2F1 pathway in cisplatin cytotoxicity in vitro and in vivo. Am J Physiol Renal Physiol. 2007;293(1):F52-59.
    • (2007) Am J Physiol Renal Physiol , vol.293 , Issue.1
    • Yu, F.1    Megyesi, J.2    Safirstein, R.L.3    Price, P.M.4
  • 49
    • 0028321891 scopus 로고
    • Derivation of androgen-independent human LNCaP prostatic cancer cell sublines: Role of bone stromal cells
    • DOI 10.1002/ijc.2910570319
    • Wu HC, Hsieh JT, Gleave ME, Brown NM, Pathak S, Chung LW. Derivation of androgen-independent human LNCaP prostatic cancer cell sublines: role of bone stromal cells. Int J Cancer. 1994;57(3):406-412. (Pubitemid 24168617)
    • (1994) International Journal of Cancer , vol.57 , Issue.3 , pp. 406-412
    • Wu, H.-C.1    Hsieh, J.-T.2    Gleave, M.E.3    Brown, N.M.4    Pathak, S.5    Chung, L.W.K.6
  • 51
    • 0038721560 scopus 로고    scopus 로고
    • Phenotypic heterogeneity of endstage prostate carcinoma metastatic to bone
    • Roudier MP, et al. Phenotypic heterogeneity of endstage prostate carcinoma metastatic to bone. Hum Pathol. 2003;34(7):646-653.
    • (2003) Hum Pathol , vol.34 , Issue.7 , pp. 646-653
    • Roudier, M.P.1
  • 52
    • 49649117206 scopus 로고    scopus 로고
    • Targeting the BAF57 SWI/SNF subunit in prostate cancer: A novel platform to control androgen receptor activity
    • Link KA, et al. Targeting the BAF57 SWI/SNF subunit in prostate cancer: a novel platform to control androgen receptor activity. Cancer Res. 2008;68(12):4551-4558.
    • (2008) Cancer Res , vol.68 , Issue.12 , pp. 4551-4558
    • Link, K.A.1
  • 53
    • 0033637703 scopus 로고    scopus 로고
    • Cofactor dynamics and sufficiency in estrogen receptor-regulated transcription
    • Shang Y, Hu X, DiRenzo J, Lazar MA, Brown M. Cofactor dynamics and sufficiency in estrogen receptor-regulated transcription. Cell. 2000;103(6):843-852.
    • (2000) Cell , vol.103 , Issue.6 , pp. 843-852
    • Shang, Y.1    Hu, X.2    DiRenzo, J.3    Lazar, M.A.4    Brown, M.5
  • 54
    • 27644506613 scopus 로고    scopus 로고
    • Integrative genomic and proteomic analysis of prostate cancer reveals signatures of metastatic progression
    • Varambally S, et al. Integrative genomic and proteomic analysis of prostate cancer reveals signatures of metastatic progression. Cancer Cell. 2005;8(5):393-406.
    • (2005) Cancer Cell , vol.8 , Issue.5 , pp. 393-406
    • Varambally, S.1
  • 56
    • 70350223620 scopus 로고    scopus 로고
    • Comparative analyses of chromosome alterations in soft-tissue metastases within and across patients with castration-resistant prostate cancer
    • Holcomb IN, et al. Comparative analyses of chromosome alterations in soft-tissue metastases within and across patients with castration-resistant prostate cancer. Cancer Res. 2009;69(19):7793-7802.
    • (2009) Cancer Res , vol.69 , Issue.19 , pp. 7793-7802
    • Holcomb, I.N.1
  • 57
    • 0032896905 scopus 로고    scopus 로고
    • Estrogen receptor status by immunohistochemistry is superior to the ligand-binding assay for predicting response to adjuvant endocrine therapy in breast cancer
    • Harvey JM, Clark GM, Osborne CK, Allred DC. Estrogen receptor status by immunohistochemistry is superior to the ligand-binding assay for predicting response to adjuvant endocrine therapy in breast cancer. J Clin Oncol. 1999;17(5):1474-1481.
    • (1999) J Clin Oncol , vol.17 , Issue.5 , pp. 1474-1481
    • Harvey, J.M.1    Clark, G.M.2    Osborne, C.K.3    Allred, D.C.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.