Activating Transcription Factor 6 Is Necessary and Sufficient for Alcoholic Fatty Liver Disease in Zebrafish

PLoS Genetics

Volumn 10, Issue 5, 2014, Pages

  Howarth, Deanna L ^a   Lindtner, Claudia ^a   Vacaru, Ana M ^a   Sachidanandam, Ravi ^a   Tsedensodnom, Orkhontuya ^a   Vasilkova, Taisa ^a   Buettner, Christoph ^a   Sadler, Kirsten C ^a  

^a MOUNT SINAI SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVATING TRANSCRIPTION FACTOR 6; FATTY ACID SYNTHASE; MESSENGER RNA; STEROL REGULATORY ELEMENT BINDING PROTEIN; TRANSCRIPTOME; TRIACYLGLYCEROL; ALCOHOL; ATF6 PROTEIN, HUMAN;

ACUTE STRESS; ADULT; ALCOHOLIC FATTY LIVER; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ATF6 GENE; CELLULAR DISTRIBUTION; CHEMICAL ANALYSIS; CHRONIC STRESS; CONTROLLED STUDY; DISEASE ASSOCIATION; EPISTASIS; FASN GENE; GENE EXPRESSION REGULATION; GENE INTERACTION; GENE OVEREXPRESSION; GENE SILENCING; GENETIC ASSOCIATION; GENETIC TRANSCRIPTION; GENOMICS; GLYCERONEOGENESIS; HEK293 CELL LINE; HEPG2 CELL LINE; HUMAN; HUMAN CELL; LARVA; LIPID METABOLISM; LIPID TRANSPORT; LIPOGENESIS; LIVER CELL; MOLECULAR DYNAMICS; MOLECULAR PATHOLOGY; NONHUMAN; NUCLEOTIDE SEQUENCE; POLYMERASE CHAIN REACTION; RNA SEQUENCE; TRANSGENIC FISH; UNFOLDED PROTEIN RESPONSE; UPREGULATION; ZEBRA FISH; ANIMAL; DISEASE MODEL; FATTY LIVER, ALCOHOLIC; GENETICS; LIVER; LIVER CELL CARCINOMA; LIVER TUMOR; METABOLISM; PATHOLOGY; TOXICITY; TRANSCRIPTION INITIATION; TRANSGENIC ANIMAL;

ACTIVATING TRANSCRIPTION FACTOR 6; ANIMALS; ANIMALS, GENETICALLY MODIFIED; CARCINOMA, HEPATOCELLULAR; DISEASE MODELS, ANIMAL; ETHANOL; FATTY LIVER, ALCOHOLIC; HEPATOCYTES; HUMANS; LIPID METABOLISM; LIVER; LIVER NEOPLASMS; TRANSCRIPTIONAL ACTIVATION; ZEBRAFISH;

EID: 84901594244     PISSN: 15537390     EISSN: 15537404     Source Type: Journal    
DOI: 10.1371/journal.pgen.1004335     Document Type: Article

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