Mechanisms of genome instability induced by RNA-processing defects

Trends in Genetics

Volumn 30, Issue 6, 2014, Pages 245-253

  Chan, Yujia A ^a   Hieter, Philip ^a,b   Stirling, Peter C ^b,c  

^a UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^b UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^c BRITISH COLUMBIA CANCER AGENCY   (Canada)

Author keywords

Cancer; Genome instability; R loops; RNA processing; Transcriptome

Indexed keywords

DOUBLE STRANDED DNA; HELICASE; RAD51 PROTEIN; RIBONUCLEASE H; RNA POLYMERASE; SEN1 HELICASE; SMALL NUCLEOLAR RNA; TRANSFER RNA; UNCLASSIFIED DRUG; RNA; TRANSCRIPTOME;

ALTERNATIVE RNA SPLICING; BIOGENESIS; CAENORHABDITIS ELEGANS; CHROMOSOMAL INSTABILITY; DNA DAMAGE; DNA METHYLATION; DNA REPAIR; DNA REPLICATION; DNA RNA HYBRIDIZATION; DNA RNA IMMUNOPRECIPITATION; ENHANCER REGION; EXOSOME; GENE MUTATION; GENE OVEREXPRESSION; GENOMIC INSTABILITY; HUMAN; IMMUNOPRECIPITATION; MAMMAL CELL; NONHUMAN; PRIORITY JOURNAL; R LOOP STRUCTURE; REVIEW; RNA DEGRADATION; RNA METABOLISM; RNA PROCESSING; RNA STRUCTURE; SACCHAROMYCES CEREVISIAE; TRANSCRIPTION REGULATION; TRANSCRIPTION TERMINATION; ANIMAL; CHEMISTRY; CONFORMATION; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; NEOPLASM; RNA SPLICING; RNA STABILITY;

ANIMALS; ENHANCER ELEMENTS, GENETIC; GENE EXPRESSION REGULATION; GENOMIC INSTABILITY; HUMANS; NEOPLASMS; NUCLEIC ACID CONFORMATION; RNA; RNA PROCESSING, POST-TRANSCRIPTIONAL; RNA SPLICING; RNA STABILITY; TRANSCRIPTOME;

EID: 84901474570     PISSN: 01689525     EISSN: 13624555     Source Type: Journal    
DOI: 10.1016/j.tig.2014.03.005     Document Type: Review

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