메뉴 건너뛰기




Volumn 8, Issue FEB, 2014, Pages

MicroRNA dysregulation in spinal cord injury: Causes, consequences, and therapeutics

Author keywords

Astrogliosis; Cell death; Inflammation; MicroRNA; Nervous system; Spinal cord injury; Therapeutics

Indexed keywords


EID: 84901468954     PISSN: 16625102     EISSN: None     Source Type: Journal    
DOI: 10.3389/fncel.2014.00053     Document Type: Review
Times cited : (111)

References (188)
  • 2
    • 4544335403 scopus 로고    scopus 로고
    • Spatial and temporal gene expression profiling of the contused rat spinal cord
    • doi: 10.1016/j.expneurol.2004.05.042
    • Aimone, J. B., Leasure, J. L., Perreau, V. M., and Thallmair, M. (2004). Spatial and temporal gene expression profiling of the contused rat spinal cord. Exp. Neurol. 189, 204-221. doi: 10.1016/j.expneurol.2004.05.042
    • (2004) Exp. Neurol. , vol.189 , pp. 204-221
    • Aimone, J.B.1    Leasure, J.L.2    Perreau, V.M.3    Thallmair, M.4
  • 3
    • 49949116902 scopus 로고    scopus 로고
    • The impact of microRNAs on protein output
    • doi: 10.1038/nature07242
    • Baek, D., Villen, J., Shin, C., Camargo, F. D., Gygi, S. P., and Bartel, D. P. (2008). The impact of microRNAs on protein output. Nature 455, 64-71. doi: 10.1038/nature07242
    • (2008) Nature , vol.455 , pp. 64-71
    • Baek, D.1    Villen, J.2    Shin, C.3    Camargo, F.D.4    Gygi, S.P.5    Bartel, D.P.6
  • 4
    • 40449124713 scopus 로고    scopus 로고
    • MicroRNA expression in the adult mouse central nervous system
    • doi: 10.1261/rna.783108
    • Bak, M., Silahtaroglu, A., Moller, M., Christensen, M., Rath, M. F., Skryabin, B., et al. (2008). MicroRNA expression in the adult mouse central nervous system. RNA 14, 432-444. doi: 10.1261/rna.783108
    • (2008) RNA , vol.14 , pp. 432-444
    • Bak, M.1    Silahtaroglu, A.2    Moller, M.3    Christensen, M.4    Rath, M.F.5    Skryabin, B.6
  • 5
    • 84860279695 scopus 로고    scopus 로고
    • MicroRNA let-7i is a promising serum biomarker for blast-induced traumatic brain injury
    • doi: 10.1089/neu.2011.2146
    • Balakathiresan, N., Bhomia, M., Chandran, R., Chavko, M., McCarron, R. M., and Maheshwari, R. K. (2012). MicroRNA let-7i is a promising serum biomarker for blast-induced traumatic brain injury. J. Neurotrauma 29, 1379-1387. doi: 10.1089/neu.2011.2146
    • (2012) J. Neurotrauma , vol.29 , pp. 1379-1387
    • Balakathiresan, N.1    Bhomia, M.2    Chandran, R.3    Chavko, M.4    McCarron, R.M.5    Maheshwari, R.K.6
  • 6
    • 0028012270 scopus 로고
    • Reactive astrogliosis in the neonatal mouse brain and its modulation by cytokines
    • Balasingam, V., Tejada-Berges, T., Wright, E., Bouckova, R., and Yong, V. W. (1994). Reactive astrogliosis in the neonatal mouse brain and its modulation by cytokines. J. Neurosci. 14, 846-856.
    • (1994) J. Neurosci. , vol.14 , pp. 846-856
    • Balasingam, V.1    Tejada-Berges, T.2    Wright, E.3    Bouckova, R.4    Yong, V.W.5
  • 7
    • 9244260503 scopus 로고    scopus 로고
    • Attenuation of astroglial reactivity by interleukin-10
    • Balasingam, V., and Yong, V. W. (1996). Attenuation of astroglial reactivity by interleukin-10. J. Neurosci. 16, 2945-2955.
    • (1996) J. Neurosci. , vol.16 , pp. 2945-2955
    • Balasingam, V.1    Yong, V.W.2
  • 8
    • 0141756286 scopus 로고    scopus 로고
    • Inflammation, degeneration and regeneration in the injured spinal cord: Insights from DNA microarrays
    • doi: 10.1016/j.tins.2003.08.004
    • Bareyre, F. M., and Schwab, M. E. (2003). Inflammation, degeneration and regeneration in the injured spinal cord: insights from DNA microarrays. Trends Neurosci. 26, 555-563. doi: 10.1016/j.tins.2003.08.004
    • (2003) Trends Neurosci. , vol.26 , pp. 555-563
    • Bareyre, F.M.1    Schwab, M.E.2
  • 9
    • 65249131826 scopus 로고    scopus 로고
    • Induction and regulatory function of miR-9 in human monocytes and neutrophils exposed to proinflammatory signals
    • doi: 10.1073/pnas.0810909106
    • Bazzoni, F., Rossato, M., Fabbri, M., Gaudiosi, D., Mirolo, M., Mori, L., et al. (2009). Induction and regulatory function of miR-9 in human monocytes and neutrophils exposed to proinflammatory signals. Proc. Natl. Acad. Sci. U.S.A. 106, 5282-5287. doi: 10.1073/pnas.0810909106
    • (2009) Proc. Natl. Acad. Sci. U.S.A. , vol.106 , pp. 5282-5287
    • Bazzoni, F.1    Rossato, M.2    Fabbri, M.3    Gaudiosi, D.4    Mirolo, M.5    Mori, L.6
  • 10
    • 77249125330 scopus 로고    scopus 로고
    • Quantitative analysis of cellular inflammation after traumatic spinal cord injury: Evidence for a multiphasic inflammatory response in the acute to chronic environment
    • doi: 10.1093/brain/awp322
    • Beck, K. D., Nguyen, H. X., Galvan, M. D., Salazar, D. L., Woodruff, T. M., and Anderson, A. J. (2010). Quantitative analysis of cellular inflammation after traumatic spinal cord injury: evidence for a multiphasic inflammatory response in the acute to chronic environment. Brain 133, 433-447. doi: 10.1093/brain/awp322
    • (2010) Brain , vol.133 , pp. 433-447
    • Beck, K.D.1    Nguyen, H.X.2    Galvan, M.D.3    Salazar, D.L.4    Woodruff, T.M.5    Anderson, A.J.6
  • 11
    • 0031025042 scopus 로고    scopus 로고
    • Axonal regrowth after spinal cord transection in adult zebrafish
    • doi: 10.1002/(SICI)1096-9861(19970127)377:4<577::AID-CNE8>3.0.CO;2-#
    • Becker, T., Wullimann, M. F., Becker, C. G., Bernhardt, R. R., and Schachner, M. (1997). Axonal regrowth after spinal cord transection in adult zebrafish. J. Comp. Neurol. 377, 577-595. doi: 10.1002/(SICI)1096-9861(19970127)377:4<577::AID-CNE8>3.0.CO;2-#
    • (1997) J. Comp. Neurol. , vol.377 , pp. 577-595
    • Becker, T.1    Wullimann, M.F.2    Becker, C.G.3    Bernhardt, R.R.4    Schachner, M.5
  • 13
    • 84870996530 scopus 로고    scopus 로고
    • MicroRNA-21 regulates astrocytic response following spinal cord injury
    • doi: 10.1523/JNEUROSCI.3860-12.2012
    • Bhalala, O. G., Pan, L., Sahni, V., McGuire, T. L., Gruner, K., Tourtellotte, W. G., et al. (2012). microRNA-21 regulates astrocytic response following spinal cord injury. J. Neurosci. 32, 17935-17947. doi: 10.1523/JNEUROSCI.3860-12.2012
    • (2012) J. Neurosci. , vol.32 , pp. 17935-17947
    • Bhalala, O.G.1    Pan, L.2    Sahni, V.3    McGuire, T.L.4    Gruner, K.5    Tourtellotte, W.G.6
  • 14
    • 84878945439 scopus 로고    scopus 로고
    • The emerging roles of microRNAs in CNS injuries
    • doi: 10.1038/nrneurol.2013.67
    • Bhalala, O. G., Srikanth, M., and Kessler, J. A. (2013). The emerging roles of microRNAs in CNS injuries. Nat. Rev. Neurol. 9, 328-339. doi: 10.1038/nrneurol.2013.67
    • (2013) Nat. Rev. Neurol. , vol.9 , pp. 328-339
    • Bhalala, O.G.1    Srikanth, M.2    Kessler, J.A.3
  • 15
    • 0025231468 scopus 로고
    • Epidemiology of spinal cord lesions in Denmark
    • doi: 10.1038/sc.1990.13
    • Biering-Sorensen, E., Pedersen, V., and Clausen, S. (1990). Epidemiology of spinal cord lesions in Denmark. Paraplegia 28, 105-118. doi: 10.1038/sc.1990.13
    • (1990) Paraplegia , vol.28 , pp. 105-118
    • Biering-Sorensen, E.1    Pedersen, V.2    Clausen, S.3
  • 16
    • 84655169651 scopus 로고    scopus 로고
    • Expression of spinal cord microRNAs in a rat model of chronic neuropathic pain
    • doi: 10.1016/j.neulet.2011.11.023
    • Brandenburger, T., Castoldi, M., Brendel, M., Grievink, H., Schlosser, L., Werdehausen, R., et al. (2012). Expression of spinal cord microRNAs in a rat model of chronic neuropathic pain. Neurosci. Lett. 506, 281-286. doi: 10.1016/j.neulet.2011.11.023
    • (2012) Neurosci. Lett. , vol.506 , pp. 281-286
    • Brandenburger, T.1    Castoldi, M.2    Brendel, M.3    Grievink, H.4    Schlosser, L.5    Werdehausen, R.6
  • 17
    • 84862496506 scopus 로고    scopus 로고
    • Complement activation in the injured central nervous system: Another dual-edged sword?
    • doi: 10.1186/1742-2094-9-137
    • Brennan, F. H., Anderson, A. J., Taylor, S. M., Woodruff, T. M., and Ruitenberg, M. J. (2012). Complement activation in the injured central nervous system: another dual-edged sword? J. Neuroinflammation 9, 137. doi: 10.1186/1742-2094-9-137
    • (2012) J. Neuroinflammation , vol.9 , pp. 137
    • Brennan, F.H.1    Anderson, A.J.2    Taylor, S.M.3    Woodruff, T.M.4    Ruitenberg, M.J.5
  • 18
    • 77957275392 scopus 로고    scopus 로고
    • MicroRNA-21 protects neurons from ischemic death
    • doi: 10.1111/j.1742-4658.2010.07818.x
    • Buller, B., Liu, X., Wang, X., Zhang, R. L., Zhang, L., Hozeska-Solgot, A., et al. (2010). MicroRNA-21 protects neurons from ischemic death. FEBS J. 277, 4299-4307. doi: 10.1111/j.1742-4658.2010.07818.x
    • (2010) FEBS J. , vol.277 , pp. 4299-4307
    • Buller, B.1    Liu, X.2    Wang, X.3    Zhang, R.L.4    Zhang, L.5    Hozeska-Solgot, A.6
  • 19
    • 33644509823 scopus 로고    scopus 로고
    • Expression of two temporally distinct microglia-related gene clusters after spinal cord injury
    • doi: 10.1002/glia.20295
    • Byrnes, K. R., Garay, J., Di Giovanni, S., De Biase, A., Knoblach, S. M., Hoffman, E. P., et al. (2006). Expression of two temporally distinct microglia-related gene clusters after spinal cord injury. Glia 53, 420-433. doi: 10.1002/glia.20295
    • (2006) Glia , vol.53 , pp. 420-433
    • Byrnes, K.R.1    Garay, J.2    Di Giovanni, S.3    De Biase, A.4    Knoblach, S.M.5    Hoffman, E.P.6
  • 20
    • 84866431344 scopus 로고    scopus 로고
    • Comparison of microarray platforms for measuring differential microRNA expression in paired normal/cancer colon tissues
    • doi: 10.1371/journal.pone.0045105
    • Callari, M., Dugo, M., Musella, V., Marchesi, E., Chiorino, G., Grand, M. M., et al. (2012). Comparison of microarray platforms for measuring differential microRNA expression in paired normal/cancer colon tissues. PLoS ONE 7:e45105. doi: 10.1371/journal.pone.0045105
    • (2012) PLoS ONE , vol.7
    • Callari, M.1    Dugo, M.2    Musella, V.3    Marchesi, E.4    Chiorino, G.5    Grand, M.M.6
  • 21
    • 0348000947 scopus 로고    scopus 로고
    • Gene expression profiling of acute spinal cord injury reveals spreading inflammatory signals and neuron loss
    • Carmel, J. B., Galante, A., Soteropoulos, P., Tolias, P., Recce, M., Young, W., et al. (2001). Gene expression profiling of acute spinal cord injury reveals spreading inflammatory signals and neuron loss. Physiol. Genomics 7, 201-213.
    • (2001) Physiol. Genomics , vol.7 , pp. 201-213
    • Carmel, J.B.1    Galante, A.2    Soteropoulos, P.3    Tolias, P.4    Recce, M.5    Young, W.6
  • 22
    • 80955158803 scopus 로고    scopus 로고
    • Posttranscriptional regulation of the β2-subunit of cardiac L-type Ca2+ channels by MicroRNAs during long-term exposure to isoproterenol in rats
    • doi: 10.1097/FJC.0b013e31822a789b
    • Carrillo, E. D., Escobar, Y., Gonzalez, G., Hernandez, A., Galindo, J. M., Garcia, M. C., et al. (2011). Posttranscriptional regulation of the β2-subunit of cardiac L-type Ca2+ channels by MicroRNAs during long-term exposure to isoproterenol in rats. J. Cardiovasc. Pharmacol. 58, 470-478. doi: 10.1097/FJC.0b013e31822a789b
    • (2011) J. Cardiovasc. Pharmacol. , vol.58 , pp. 470-478
    • Carrillo, E.D.1    Escobar, Y.2    Gonzalez, G.3    Hernandez, A.4    Galindo, J.M.5    Garcia, M.C.6
  • 23
    • 0035961212 scopus 로고    scopus 로고
    • Oligodendroglial apoptosis occurs along degenerating axons and is associated with FAS and p75 expression following spinal cord injury in the rat
    • doi: 10.1016/S0306-4522(00)00538-8
    • Casha, S., Yu, W. R., and Fehlings, M. G. (2001). Oligodendroglial apoptosis occurs along degenerating axons and is associated with FAS and p75 expression following spinal cord injury in the rat. Neuroscience 103, 203-218. doi: 10.1016/S0306-4522(00)00538-8
    • (2001) Neuroscience , vol.103 , pp. 203-218
    • Casha, S.1    Yu, W.R.2    Fehlings, M.G.3
  • 24
    • 84883057318 scopus 로고    scopus 로고
    • Genome-wide gene expression profiling of stress response in a spinal cord clip compression injury model
    • doi: 10.1186/1471-2164-14-583
    • Chamankhah, M., Eftekharpour, E., Karimi-Abdolrezaee, S., Boutros, P. C., San-Marina, S., and Fehlings, M. G. (2013). Genome-wide gene expression profiling of stress response in a spinal cord clip compression injury model. BMC Genomics 14:583. doi: 10.1186/1471-2164-14-583
    • (2013) BMC Genomics , vol.14 , pp. 583
    • Chamankhah, M.1    Eftekharpour, E.2    Karimi-Abdolrezaee, S.3    Boutros, P.C.4    San-Marina, S.5    Fehlings, M.G.6
  • 25
    • 37549008310 scopus 로고    scopus 로고
    • Widespread microRNA repression by Myc contributes to tumorigenesis
    • doi: 10.1038/ng.2007.30
    • Chang, T. C., Yu, D., Lee, Y. S., Wentzel, E. A., Arking, D. E., West, K. M., et al. (2008). Widespread microRNA repression by Myc contributes to tumorigenesis. Nat. Genet. 40, 43-50. doi: 10.1038/ng.2007.30
    • (2008) Nat. Genet. , vol.40 , pp. 43-50
    • Chang, T.C.1    Yu, D.2    Lee, Y.S.3    Wentzel, E.A.4    Arking, D.E.5    West, K.M.6
  • 26
    • 84875769575 scopus 로고    scopus 로고
    • Regulation of immune responses and tolerance: The microRNA perspective
    • doi: 10.1111/imr.12060
    • Chen, C. Z., Schaffert, S., Fragoso, R., and Loh, C. (2013). Regulation of immune responses and tolerance: the microRNA perspective. Immunol. Rev. 253, 112-128. doi: 10.1111/imr.12060
    • (2013) Immunol. Rev. , vol.253 , pp. 112-128
    • Chen, C.Z.1    Schaffert, S.2    Fragoso, R.3    Loh, C.4
  • 27
    • 49149091917 scopus 로고    scopus 로고
    • Regulation of IKKβ by miR-199a affects NF-κB activity in ovarian cancer cells
    • doi: 10.1038/onc.2008.112
    • Chen, R., Alvero, A. B., Silasi, D. A., Kelly, M. G., Fest, S., Visintin, I., et al. (2008). Regulation of IKKβ by miR-199a affects NF-κB activity in ovarian cancer cells. Oncogene 27, 4712-4723. doi: 10.1038/onc.2008.112
    • (2008) Oncogene , vol.27 , pp. 4712-4723
    • Chen, R.1    Alvero, A.B.2    Silasi, D.A.3    Kelly, M.G.4    Fest, S.5    Visintin, I.6
  • 28
    • 84862777377 scopus 로고    scopus 로고
    • Secreted microRNAs: A new form of intercellular communication
    • doi: 10.1016/j.tcb.2011.12.001
    • Chen, X., Liang, H., Zhang, J., Zen, K., and Zhang, C. Y. (2012). Secreted microRNAs: a new form of intercellular communication. Trends Cell Biol. 22, 125-132. doi: 10.1016/j.tcb.2011.12.001
    • (2012) Trends Cell Biol. , vol.22 , pp. 125-132
    • Chen, X.1    Liang, H.2    Zhang, J.3    Zen, K.4    Zhang, C.Y.5
  • 30
    • 0033664631 scopus 로고    scopus 로고
    • Rapid upregulation of caspase-3 in rat spinal cord after injury: MRNA, protein, and cellular localization correlates with apoptotic cell death
    • doi: 10.1006/exnr.2000.7523
    • Citron, B. A., Arnold, P. M., Sebastian, C., Qin, F., Malladi, S., Ameenuddin, S., et al. (2000). Rapid upregulation of caspase-3 in rat spinal cord after injury: mRNA, protein, and cellular localization correlates with apoptotic cell death. Exp. Neurol. 166, 213-226. doi: 10.1006/exnr.2000.7523
    • (2000) Exp. Neurol. , vol.166 , pp. 213-226
    • Citron, B.A.1    Arnold, P.M.2    Sebastian, C.3    Qin, F.4    Malladi, S.5    Ameenuddin, S.6
  • 31
    • 77952104584 scopus 로고    scopus 로고
    • Statistical expression deconvolution from mixed tissue samples
    • doi: 10.1093/bioinformatics/btq097
    • Clarke, J., Seo, P., and Clarke, B. (2010). Statistical expression deconvolution from mixed tissue samples. Bioinformatics 26, 1043-1049. doi: 10.1093/bioinformatics/btq097
    • (2010) Bioinformatics , vol.26 , pp. 1043-1049
    • Clarke, J.1    Seo, P.2    Clarke, B.3
  • 32
    • 84857422765 scopus 로고    scopus 로고
    • Diverse functions of microRNAs in nervous system development
    • doi: 10.1016/B978-0-12-387038-4.00005-7
    • Cochella, L., and Hobert, O. (2012). Diverse functions of microRNAs in nervous system development. Curr. Top. Dev. Biol. 99, 115-143. doi: 10.1016/B978-0-12-387038-4.00005-7
    • (2012) Curr. Top. Dev. Biol. , vol.99 , pp. 115-143
    • Cochella, L.1    Hobert, O.2
  • 33
    • 0031015075 scopus 로고    scopus 로고
    • Apoptosis and delayed degeneration after spinal cord injury in rats and monkeys
    • doi: 10.1038/nm0197-73
    • Crowe, M. J., Bresnahan, J. C., Shuman, S. L., Masters, J. N., and Beattie, M. S. (1997). Apoptosis and delayed degeneration after spinal cord injury in rats and monkeys. Nat. Med. 3, 73-76. doi: 10.1038/nm0197-73
    • (1997) Nat. Med. , vol.3 , pp. 73-76
    • Crowe, M.J.1    Bresnahan, J.C.2    Shuman, S.L.3    Masters, J.N.4    Beattie, M.S.5
  • 34
    • 78649863208 scopus 로고    scopus 로고
    • Differential regulation of interleukin-1 receptor-associated kinase-1 (IRAK-1) and IRAK-2 by microRNA-146a and NF-kappaB in stressed human astroglial cells and in Alzheimer disease
    • doi: 10.1074/jbc.M110.178848
    • Cui, J. G., Li, Y. Y., Zhao, Y., Bhattacharjee, S., and Lukiw, W. J. (2010). Differential regulation of interleukin-1 receptor-associated kinase-1 (IRAK-1) and IRAK-2 by microRNA-146a and NF-kappaB in stressed human astroglial cells and in Alzheimer disease. J. Biol. Chem. 285, 38951-38960. doi: 10.1074/jbc.M110.178848
    • (2010) J. Biol. Chem. , vol.285 , pp. 38951-38960
    • Cui, J.G.1    Li, Y.Y.2    Zhao, Y.3    Bhattacharjee, S.4    Lukiw, W.J.5
  • 35
    • 0019856865 scopus 로고
    • Axonal elongation into peripheral nervous system "bridges" after central nervous system injury in adult rats
    • doi: 10.1126/science.6171034
    • David, S., and Aguayo, A. J. (1981). Axonal elongation into peripheral nervous system "bridges" after central nervous system injury in adult rats. Science 214, 931-933. doi: 10.1126/science.6171034
    • (1981) Science , vol.214 , pp. 931-933
    • David, S.1    Aguayo, A.J.2
  • 36
    • 77955484492 scopus 로고    scopus 로고
    • Smad proteins bind a conserved RNA sequence to promote microRNA maturation by Drosha
    • doi: 10.1016/j.molcel.2010.07.011
    • Davis, B. N., Hilyard, A. C., Nguyen, P. H., Lagna, G., and Hata, A. (2010). Smad proteins bind a conserved RNA sequence to promote microRNA maturation by Drosha. Mol. Cell 39, 373-384. doi: 10.1016/j.molcel.2010.07.011
    • (2010) Mol. Cell , vol.39 , pp. 373-384
    • Davis, B.N.1    Hilyard, A.C.2    Nguyen, P.H.3    Lagna, G.4    Hata, A.5
  • 37
    • 25144506952 scopus 로고    scopus 로고
    • Gene expression profiling of experimental traumatic spinal cord injury as a function of distance from impact site and injury severity
    • doi: 10.1152/physiolgenomics.00081.2005
    • De Biase, A., Knoblach, S. M., Di Giovanni, S., Fan, C., Molon, A., Hoffman, E. P., et al. (2005). Gene expression profiling of experimental traumatic spinal cord injury as a function of distance from impact site and injury severity. Physiol. Genomics 22, 368-381. doi: 10.1152/physiolgenomics.00081.2005
    • (2005) Physiol. Genomics , vol.22 , pp. 368-381
    • De Biase, A.1    Knoblach, S.M.2    Di Giovanni, S.3    Fan, C.4    Molon, A.5    Hoffman, E.P.6
  • 38
    • 33748310866 scopus 로고    scopus 로고
    • Detection of mammalian microRNA expression by in situ hybridization with RNA oligonucleotides
    • doi: 10.1002/dvdy.20847
    • Deo, M., Yu, J. Y., Chung, K. H., Tippens, M., and Turner, D. L. (2006). Detection of mammalian microRNA expression by in situ hybridization with RNA oligonucleotides. Dev. Dyn. 235, 2538-2548. doi: 10.1002/dvdy.20847
    • (2006) Dev. Dyn. , vol.235 , pp. 2538-2548
    • Deo, M.1    Yu, J.Y.2    Chung, K.H.3    Tippens, M.4    Turner, D.L.5
  • 39
    • 63949084047 scopus 로고    scopus 로고
    • Transient focal ischemia induces extensive temporal changes in rat cerebral microRNAome
    • doi: 10.1038/jcbfm.2008.157
    • Dharap, A., Bowen, K., Place, R., Li, L. C., and Vemuganti, R. (2009). Transient focal ischemia induces extensive temporal changes in rat cerebral microRNAome. J. Cereb. Blood Flow Metab. 29, 675-687. doi: 10.1038/jcbfm.2008.157
    • (2009) J. Cereb. Blood Flow Metab. , vol.29 , pp. 675-687
    • Dharap, A.1    Bowen, K.2    Place, R.3    Li, L.C.4    Vemuganti, R.5
  • 40
    • 12544249903 scopus 로고    scopus 로고
    • In vivo and in vitro characterization of novel neuronal plasticity factors identified following spinal cord injury
    • doi: 10.1074/jbc.M411975200
    • Di Giovanni, S., De Biase, A., Yakovlev, A., Finn, T., Beers, J., Hoffman, E. P., et al. (2005a). In vivo and in vitro characterization of novel neuronal plasticity factors identified following spinal cord injury. J. Biol. Chem. 280, 2084-2091. doi: 10.1074/jbc.M411975200
    • (2005) J. Biol. Chem. , vol.280 , pp. 2084-2091
    • Di Giovanni, S.1    De Biase, A.2    Yakovlev, A.3    Finn, T.4    Beers, J.5    Hoffman, E.P.6
  • 41
    • 19944429593 scopus 로고    scopus 로고
    • Neuronal plasticity after spinal cord injury: Identification of a gene cluster driving neurite outgrowth
    • Di Giovanni, S., Faden, A. I., Yakovlev, A., Duke-Cohan, J. S., Finn, T., Thouin, M., et al. (2005b). Neuronal plasticity after spinal cord injury: identification of a gene cluster driving neurite outgrowth. FASEB J. 19, 153-154.
    • (2005) FASEB J. , vol.19 , pp. 153-154
    • Di Giovanni, S.1    Faden, A.I.2    Yakovlev, A.3    Duke-Cohan, J.S.4    Finn, T.5    Thouin, M.6
  • 42
    • 0037379603 scopus 로고    scopus 로고
    • Gene profiling in spinal cord injury shows role of cell cycle in neuronal death
    • doi: 10.1002/ana.10472
    • Di Giovanni, S., Knoblach, S. M., Brandoli, C., Aden, S. A., Hoffman, E. P., and Faden, A. I. (2003). Gene profiling in spinal cord injury shows role of cell cycle in neuronal death. Ann. Neurol. 53, 454-468. doi: 10.1002/ana.10472
    • (2003) Ann. Neurol. , vol.53 , pp. 454-468
    • Di Giovanni, S.1    Knoblach, S.M.2    Brandoli, C.3    Aden, S.A.4    Hoffman, E.P.5    Faden, A.I.6
  • 43
    • 38749086493 scopus 로고    scopus 로고
    • Inflammation and its role in neuroprotection, axonal regeneration and functional recovery after spinal cord injury
    • doi: 10.1016/j.expneurol.2007.06.009
    • Donnelly, D. J., and Popovich, P. G. (2008). Inflammation and its role in neuroprotection, axonal regeneration and functional recovery after spinal cord injury. Exp. Neurol. 209, 378-388. doi: 10.1016/j.expneurol.2007.06.009
    • (2008) Exp. Neurol. , vol.209 , pp. 378-388
    • Donnelly, D.J.1    Popovich, P.G.2
  • 44
    • 77649175470 scopus 로고    scopus 로고
    • Dicer1 and miR-219 Are required for normal oligodendrocyte differentiation and myelination
    • doi: 10.1016/j.neuron.2010.01.027
    • Dugas, J. C., Cuellar, T. L., Scholze, A., Ason, B., Ibrahim, A., Emery, B., et al. (2010). Dicer1 and miR-219 Are required for normal oligodendrocyte differentiation and myelination. Neuron 65, 597-611. doi: 10.1016/j.neuron.2010.01.027
    • (2010) Neuron , vol.65 , pp. 597-611
    • Dugas, J.C.1    Cuellar, T.L.2    Scholze, A.3    Ason, B.4    Ibrahim, A.5    Emery, B.6
  • 45
    • 0034806962 scopus 로고    scopus 로고
    • Acute spinal cord injury, part I: Pathophysiologic mechanisms
    • doi: 10.1097/00002826-200109000-00002
    • Dumont, R. J., Okonkwo, D. O., Verma, S., Hurlbert, R. J., Boulos, P. T., Ellegala, D. B., et al. (2001). Acute spinal cord injury, part I: pathophysiologic mechanisms. Clin. Neuropharmacol. 24, 254-264. doi: 10.1097/00002826-200109000-00002
    • (2001) Clin. Neuropharmacol. , vol.24 , pp. 254-264
    • Dumont, R.J.1    Okonkwo, D.O.2    Verma, S.3    Hurlbert, R.J.4    Boulos, P.T.5    Ellegala, D.B.6
  • 46
    • 84860324470 scopus 로고    scopus 로고
    • Roles for microRNAs in conferring robustness to biological processes
    • doi: 10.1016/j.cell.2012.04.005
    • Ebert, M. S., and Sharp, P. A. (2012). Roles for microRNAs in conferring robustness to biological processes. Cell 149, 515-524. doi: 10.1016/j.cell.2012.04.005
    • (2012) Cell , vol.149 , pp. 515-524
    • Ebert, M.S.1    Sharp, P.A.2
  • 47
    • 1542317072 scopus 로고    scopus 로고
    • Reactive astrocytes protect tissue and preserve function after spinal cord injury
    • doi: 10.1523/JNEUROSCI.3547-03.2004
    • Faulkner, J. R., Herrmann, J. E., Woo, M. J., Tansey, K. E., Doan, N. B., and Sofroniew, M. V. (2004). Reactive astrocytes protect tissue and preserve function after spinal cord injury. J. Neurosci. 24, 2143-2155. doi: 10.1523/JNEUROSCI.3547-03.2004
    • (2004) J. Neurosci. , vol.24 , pp. 2143-2155
    • Faulkner, J.R.1    Herrmann, J.E.2    Woo, M.J.3    Tansey, K.E.4    Doan, N.B.5    Sofroniew, M.V.6
  • 48
    • 0033180342 scopus 로고    scopus 로고
    • The glial scar and central nervous system repair
    • doi: 10.1016/S0361-9230(99)00072-6
    • Fawcett, J. W., and Asher, R. A. (1999). The glial scar and central nervous system repair. Brain Res. Bull. 49, 377-391. doi: 10.1016/S0361-9230(99)00072-6
    • (1999) Brain Res. Bull. , vol.49 , pp. 377-391
    • Fawcett, J.W.1    Asher, R.A.2
  • 49
    • 0029012783 scopus 로고
    • The relationships among the severity of spinal cord injury, residual neurological function, axon counts, and counts of retrogradely labeled neurons after experimental spinal cord injury
    • doi: 10.1016/0014-4886(95)90027-6
    • Fehlings, M. G., and Tator, C. H. (1995). The relationships among the severity of spinal cord injury, residual neurological function, axon counts, and counts of retrogradely labeled neurons after experimental spinal cord injury. Exp. Neurol. 132, 220-228. doi: 10.1016/0014-4886(95)90027-6
    • (1995) Exp. Neurol. , vol.132 , pp. 220-228
    • Fehlings, M.G.1    Tator, C.H.2
  • 50
    • 33845332735 scopus 로고    scopus 로고
    • The cellular inflammatory response in human spinal cords after injury
    • doi: 10.1093/brain/awl296
    • Fleming, J. C., Norenberg, M. D., Ramsay, D. A., Dekaban, G. A., Marcillo, A. E., Saenz, A. D., et al. (2006). The cellular inflammatory response in human spinal cords after injury. Brain 129, 3249-3269. doi: 10.1093/brain/awl296
    • (2006) Brain , vol.129 , pp. 3249-3269
    • Fleming, J.C.1    Norenberg, M.D.2    Ramsay, D.A.3    Dekaban, G.A.4    Marcillo, A.E.5    Saenz, A.D.6
  • 51
    • 38149042783 scopus 로고    scopus 로고
    • Programmed cell death 4 (PDCD4) is an important functional target of the microRNA miR-21 in breast cancer cells
    • doi: 10.1074/jbc.M707224200
    • Frankel, L. B., Christoffersen, N. R., Jacobsen, A., Lindow, M., Krogh, A., and Lund, A. H. (2008). Programmed cell death 4 (PDCD4) is an important functional target of the microRNA miR-21 in breast cancer cells. J. Biol. Chem. 283, 1026-1033. doi: 10.1074/jbc.M707224200
    • (2008) J. Biol. Chem. , vol.283 , pp. 1026-1033
    • Frankel, L.B.1    Christoffersen, N.R.2    Jacobsen, A.3    Lindow, M.4    Krogh, A.5    Lund, A.H.6
  • 52
    • 60149095444 scopus 로고    scopus 로고
    • Most mammalian mRNAs are conserved targets of microRNAs
    • doi: 10.1101/gr.082701.108
    • Friedman, R. C., Farh, K. K., Burge, C. B., and Bartel, D. P. (2009). Most mammalian mRNAs are conserved targets of microRNAs. Genome Res. 19, 92-105. doi: 10.1101/gr.082701.108
    • (2009) Genome Res. , vol.19 , pp. 92-105
    • Friedman, R.C.1    Farh, K.K.2    Burge, C.B.3    Bartel, D.P.4
  • 53
    • 58149390112 scopus 로고    scopus 로고
    • Deficiency in complement C1q improves histological and functional locomotor outcome after spinal cord injury
    • doi: 10.1523/JNEUROSCI.2823-08.2008
    • Galvan, M. D., Luchetti, S., Burgos, A. M., Nguyen, H. X., Hooshmand, M. J., Hamers, F. P., et al. (2008). Deficiency in complement C1q improves histological and functional locomotor outcome after spinal cord injury. J. Neurosci. 28, 13876-13888. doi: 10.1523/JNEUROSCI.2823-08.2008
    • (2008) J. Neurosci. , vol.28 , pp. 13876-13888
    • Galvan, M.D.1    Luchetti, S.2    Burgos, A.M.3    Nguyen, H.X.4    Hooshmand, M.J.5    Hamers, F.P.6
  • 54
    • 58849163959 scopus 로고    scopus 로고
    • MicroRNAs: Key regulators of stem cells
    • doi: 10.1038/nrm2621
    • Gangaraju, V. K., and Lin, H. (2009). MicroRNAs: key regulators of stem cells. Nat. Rev. Mol. Cell Biol. 10, 116-125. doi: 10.1038/nrm2621
    • (2009) Nat. Rev. Mol. Cell Biol. , vol.10 , pp. 116-125
    • Gangaraju, V.K.1    Lin, H.2
  • 55
    • 84873186621 scopus 로고    scopus 로고
    • MicroRNA changes in the dorsal horn of the spinal cord of rats with chronic constriction injury: A TaqMan(R) Low Density Array study
    • doi: 10.3892/ijmm.2012.1163
    • Genda, Y., Arai, M., Ishikawa, M., Tanaka, S., Okabe, T., and Sakamoto, A. (2013). microRNA changes in the dorsal horn of the spinal cord of rats with chronic constriction injury: a TaqMan(R) Low Density Array study. Int. J. Mol. Med. 31, 129-137. doi: 10.3892/ijmm.2012.1163
    • (2013) Int. J. Mol. Med. , vol.31 , pp. 129-137
    • Genda, Y.1    Arai, M.2    Ishikawa, M.3    Tanaka, S.4    Okabe, T.5    Sakamoto, A.6
  • 56
    • 77951190661 scopus 로고    scopus 로고
    • Systematic comparison of microarray profiling, real-time PCR, and next-generation sequencing technologies for measuring differential microRNA expression
    • doi: 10.1261/rna.1947110
    • Git, A., Dvinge, H., Salmon-Divon, M., Osborne, M., Kutter, C., Hadfield, J., et al. (2010). Systematic comparison of microarray profiling, real-time PCR, and next-generation sequencing technologies for measuring differential microRNA expression. RNA 16, 991-1006. doi: 10.1261/rna.1947110
    • (2010) RNA , vol.16 , pp. 991-1006
    • Git, A.1    Dvinge, H.2    Salmon-Divon, M.3    Osborne, M.4    Kutter, C.5    Hadfield, J.6
  • 57
    • 0036216728 scopus 로고    scopus 로고
    • Fibroblast growth factor-2 induces astroglial and microglial reactivity in vivo
    • doi: 10.1046/j.0021-8782.2001.00002.x
    • Goddard, D. R., Berry, M., Kirvell, S. L., and Butt, A. M. (2002). Fibroblast growth factor-2 induces astroglial and microglial reactivity in vivo. J. Anat. 200, 57-67. doi: 10.1046/j.0021-8782.2001.00002.x
    • (2002) J. Anat. , vol.200 , pp. 57-67
    • Goddard, D.R.1    Berry, M.2    Kirvell, S.L.3    Butt, A.M.4
  • 58
    • 0037447204 scopus 로고    scopus 로고
    • How does an axon grow?
    • doi: 10.1101/gad.1062303
    • Goldberg, J. L. (2003). How does an axon grow? Genes Dev. 17, 941-958. doi: 10.1101/gad.1062303
    • (2003) Genes Dev. , vol.17 , pp. 941-958
    • Goldberg, J.L.1
  • 59
    • 84856738488 scopus 로고    scopus 로고
    • Post-transcriptional trafficking and regulation of neuronal gene expression
    • doi: 10.1007/s12035-011-8222-0
    • Goldie, B. J., and Cairns, M. J. (2012). Post-transcriptional trafficking and regulation of neuronal gene expression. Mol. Neurobiol. 45, 99-108. doi: 10.1007/s12035-011-8222-0
    • (2012) Mol. Neurobiol. , vol.45 , pp. 99-108
    • Goldie, B.J.1    Cairns, M.J.2
  • 60
    • 36948998970 scopus 로고    scopus 로고
    • Electronically subtracting expression patterns from a mixed cell population
    • doi: 10.1093/bioinformatics/btm508
    • Gosink, M. M., Petrie, H. T., and Tsinoremas, N. F. (2007). Electronically subtracting expression patterns from a mixed cell population. Bioinformatics 23, 3328-3334. doi: 10.1093/bioinformatics/btm508
    • (2007) Bioinformatics , vol.23 , pp. 3328-3334
    • Gosink, M.M.1    Petrie, H.T.2    Tsinoremas, N.F.3
  • 61
    • 0035074297 scopus 로고    scopus 로고
    • Temporal-spatial pattern of acute neuronal and glial loss after spinal cord contusion
    • doi: 10.1006/exnr.2001.7628
    • Grossman, S. D., Rosenberg, L. J., and Wrathall, J. R. (2001). Temporal-spatial pattern of acute neuronal and glial loss after spinal cord contusion. Exp. Neurol. 168, 273-282. doi: 10.1006/exnr.2001.7628
    • (2001) Exp. Neurol. , vol.168 , pp. 273-282
    • Grossman, S.D.1    Rosenberg, L.J.2    Wrathall, J.R.3
  • 62
    • 84878648745 scopus 로고    scopus 로고
    • Involvement of microRNA in microglia-mediated immune response
    • doi: 10.1155/2013/186872
    • Guedes, J., Cardoso, A. L., and Pedroso de Lima, M. C. (2013). Involvement of microRNA in microglia-mediated immune response. Clin. Dev. Immunol. 2013, 186872. doi: 10.1155/2013/186872
    • (2013) Clin. Dev. Immunol. , vol.2013 , pp. 186872
    • Guedes, J.1    Cardoso, A.L.2    de Lima Pedroso, M.C.3
  • 63
    • 77955644289 scopus 로고    scopus 로고
    • Mammalian microRNAs predominantly act to decrease target mRNA levels
    • doi: 10.1038/nature09267
    • Guo, H., Ingolia, N. T., Weissman, J. S., and Bartel, D. P. (2010). Mammalian microRNAs predominantly act to decrease target mRNA levels. Nature 466, 835-840. doi: 10.1038/nature09267
    • (2010) Nature , vol.466 , pp. 835-840
    • Guo, H.1    Ingolia, N.T.2    Weissman, J.S.3    Bartel, D.P.4
  • 64
    • 84866440190 scopus 로고    scopus 로고
    • MicroRNAs and metastasis-related gene expression in Egyptian breast cancer patients
    • doi: 10.7314/APJCP.2012.13.2.591
    • Hafez, M. M., Hassan, Z. K., Zekri, A. R., Gaber, A. A., Al Rejaie, S. S., Sayed-Ahmed, M. M., et al. (2012). MicroRNAs and metastasis-related gene expression in Egyptian breast cancer patients. Asian Pac. J. Cancer Prev. 13, 591-598. doi: 10.7314/APJCP.2012.13.2.591
    • (2012) Asian Pac. J. Cancer Prev. , vol.13 , pp. 591-598
    • Hafez, M.M.1    Hassan, Z.K.2    Zekri, A.R.3    Gaber, A.A.4    Al Rejaie, S.S.5    Sayed-Ahmed, M.M.6
  • 65
    • 84862638243 scopus 로고    scopus 로고
    • Antagonism of miR-21 reverses epithelial-mesenchymal transition and cancer stem cell phenotype through AKT/ERK1/2 inactivation by targeting PTEN
    • doi: 10.1371/journal.pone.0039520
    • Han, M., Liu, M., Wang, Y., Chen, X., Xu, J., Sun, Y., et al. (2012). Antagonism of miR-21 reverses epithelial-mesenchymal transition and cancer stem cell phenotype through AKT/ERK1/2 inactivation by targeting PTEN. PLoS ONE 7:e39520. doi: 10.1371/journal.pone.0039520
    • (2012) PLoS ONE , vol.7
    • Han, M.1    Liu, M.2    Wang, Y.3    Chen, X.4    Xu, J.5    Sun, Y.6
  • 66
    • 40349103409 scopus 로고    scopus 로고
    • MicroRNA-126 regulates endothelial expression of vascular cell adhesion molecule 1
    • doi: 10.1073/pnas.0707493105
    • Harris, T. A., Yamakuchi, M., Ferlito, M., Mendell, J. T., and Lowenstein, C. J. (2008). MicroRNA-126 regulates endothelial expression of vascular cell adhesion molecule 1. Proc. Natl. Acad. Sci. U.S.A. 105, 1516-1521. doi: 10.1073/pnas.0707493105
    • (2008) Proc. Natl. Acad. Sci. U.S.A. , vol.105 , pp. 1516-1521
    • Harris, T.A.1    Yamakuchi, M.2    Ferlito, M.3    Mendell, J.T.4    Lowenstein, C.J.5
  • 67
    • 0038340422 scopus 로고    scopus 로고
    • Post-traumatic inflammation following spinal cord injury
    • doi: 10.1038/sj.sc.3101483
    • Hausmann, O. N. (2003). Post-traumatic inflammation following spinal cord injury. Spinal Cord 41, 369-378. doi: 10.1038/sj.sc.3101483
    • (2003) Spinal Cord , vol.41 , pp. 369-378
    • Hausmann, O.N.1
  • 68
    • 84885078339 scopus 로고    scopus 로고
    • MicroRNA function is required for neurite outgrowth of mature neurons in the mouse postnatal cerebral cortex
    • doi: 10.3389/fncel.2013.00151
    • Hong, J., Zhang, H., Kawase-Koga, Y., and Sun, T. (2013). MicroRNA function is required for neurite outgrowth of mature neurons in the mouse postnatal cerebral cortex. Front. Cell. Neurosci. 7:151. doi: 10.3389/fncel.2013.00151
    • (2013) Front. Cell. Neurosci. , vol.7 , pp. 151
    • Hong, J.1    Zhang, H.2    Kawase-Koga, Y.3    Sun, T.4
  • 69
    • 84877618350 scopus 로고    scopus 로고
    • Altered microRNA expression in the ischemic-reperfusion spinal cord with atorvastatin therapy
    • doi: 10.1254/jphs.12235SC
    • Hu, J. R., Lv, G. H., and Yin, B. L. (2013a). Altered microRNA expression in the ischemic-reperfusion spinal cord with atorvastatin therapy. J. Pharmacol. Sci. 121, 343-346. doi: 10.1254/jphs.12235SC
    • (2013) J. Pharmacol. Sci. , vol.121 , pp. 343-346
    • Hu, J.R.1    Lv, G.H.2    Yin, B.L.3
  • 70
    • 84881073661 scopus 로고    scopus 로고
    • Anti-apoptotic effect of microRNA-21 after contusion spinal cord injury in rats
    • doi: 10.1089/neu.2012.2748
    • Hu, J. Z., Huang, J. H., Zeng, L., Wang, G., Cao, M., and Lu, H. B. (2013b). Anti-apoptotic effect of microRNA-21 after contusion spinal cord injury in rats. J. Neurotrauma 30, 1349-1360. doi: 10.1089/neu.2012.2748
    • (2013) J. Neurotrauma , vol.30 , pp. 1349-1360
    • Hu, J.Z.1    Huang, J.H.2    Zeng, L.3    Wang, G.4    Cao, M.5    Lu, H.B.6
  • 71
    • 84879604742 scopus 로고    scopus 로고
    • Evidence for miR-181 involvement in neuroinflammatory responses of astrocytes
    • doi: 10.1002/glia.22483
    • Hutchison, E. R., Kawamoto, E. M., Taub, D. D., Lal, A., Abdelmohsen, K., Zhang, Y., et al. (2013). Evidence for miR-181 involvement in neuroinflammatory responses of astrocytes. Glia 61, 1018-1028. doi: 10.1002/glia.22483
    • (2013) Glia , vol.61 , pp. 1018-1028
    • Hutchison, E.R.1    Kawamoto, E.M.2    Taub, D.D.3    Lal, A.4    Abdelmohsen, K.5    Zhang, Y.6
  • 72
    • 84895726984 scopus 로고    scopus 로고
    • Clinical applications of microRNAs
    • doi: 10.12688/f1000research.2-136.v3
    • Hydbring, P., and Badalian-Very, G. (2013). Clinical applications of microRNAs. F1000Research 2, 136. doi: 10.12688/f1000research.2-136.v3
    • (2013) F1000Research , vol.2 , pp. 136
    • Hydbring, P.1    Badalian-Very, G.2
  • 73
    • 70350778443 scopus 로고    scopus 로고
    • An epigenetic switch involving NF-kappaB, lin28, Let-7 microRNA, and IL6 links inflammation to cell transformation
    • doi: 10.1016/j.cell.2009.10.014
    • Iliopoulos, D., Hirsch, H. A., and Struhl, K. (2009). An epigenetic switch involving NF-kappaB, lin28, Let-7 microRNA, and IL6 links inflammation to cell transformation. Cell 139, 693-706. doi: 10.1016/j.cell.2009.10.014
    • (2009) Cell , vol.139 , pp. 693-706
    • Iliopoulos, D.1    Hirsch, H.A.2    Struhl, K.3
  • 74
    • 77955992756 scopus 로고    scopus 로고
    • STAT3 activation of miR-21 and miR-181b-1 via PTEN and CYLD are part of the epigenetic switch linking inflammation to cancer
    • doi: 10.1016/j.molcel.2010.07.023
    • Iliopoulos, D., Jaeger, S. A., Hirsch, H. A., Bulyk, M. L., and Struhl, K. (2010). STAT3 activation of miR-21 and miR-181b-1 via PTEN and CYLD are part of the epigenetic switch linking inflammation to cancer. Mol. Cell 39, 493-506. doi: 10.1016/j.molcel.2010.07.023
    • (2010) Mol. Cell , vol.39 , pp. 493-506
    • Iliopoulos, D.1    Jaeger, S.A.2    Hirsch, H.A.3    Bulyk, M.L.4    Struhl, K.5
  • 75
    • 84870562398 scopus 로고    scopus 로고
    • Molecular targeting of NOX4 for neuropathic pain after traumatic injury of the spinal cord
    • doi: 10.1038/cddis.2012.168
    • Im, Y. B., Jee, M. K., Choi, J. I., Cho, H. T., Kwon, O. H., and Kang, S. K. (2012). Molecular targeting of NOX4 for neuropathic pain after traumatic injury of the spinal cord. Cell Death Dis. 3, e426. doi: 10.1038/cddis.2012.168
    • (2012) Cell Death Dis. , vol.3
    • Im, Y.B.1    Jee, M.K.2    Choi, J.I.3    Cho, H.T.4    Kwon, O.H.5    Kang, S.K.6
  • 76
    • 84866369867 scopus 로고    scopus 로고
    • MicroRNA-146a: A key regulator of astrocyte-mediated inflammatory response
    • doi: 10.1371/journal.pone.0044789
    • Iyer, A., Zurolo, E., Prabowo, A., Fluiter, K., Spliet, W. G., van Rijen, P. C., et al. (2012). MicroRNA-146a: a key regulator of astrocyte-mediated inflammatory response. PLoS ONE 7:e44789. doi: 10.1371/journal.pone.0044789
    • (2012) PLoS ONE , vol.7
    • Iyer, A.1    Zurolo, E.2    Prabowo, A.3    Fluiter, K.4    Spliet, W.G.5    van Rijen, P.C.6
  • 77
    • 79952071545 scopus 로고    scopus 로고
    • MicroRNA-223 expression in neutrophils in the early phase of secondary damage after spinal cord injury
    • doi: 10.1016/j.neulet.2011.01.068
    • Izumi, B., Nakasa, T., Tanaka, N., Nakanishi, K., Kamei, N., Yamamoto, R., et al. (2011). MicroRNA-223 expression in neutrophils in the early phase of secondary damage after spinal cord injury. Neurosci. Lett. 492, 114-118. doi: 10.1016/j.neulet.2011.01.068
    • (2011) Neurosci. Lett. , vol.492 , pp. 114-118
    • Izumi, B.1    Nakasa, T.2    Tanaka, N.3    Nakanishi, K.4    Kamei, N.5    Yamamoto, R.6
  • 78
    • 84860136539 scopus 로고    scopus 로고
    • MicroRNA 486 is a potentially novel target for the treatment of spinal cord injury
    • doi: 10.1093/brain/aws047
    • Jee, M. K., Jung, J. S., Choi, J. I., Jang, J. A., Kang, K. S., Im, Y. B., et al. (2012a). MicroRNA 486 is a potentially novel target for the treatment of spinal cord injury. Brain, 135, 1237-1252. doi: 10.1093/brain/aws047
    • (2012) Brain , vol.135 , pp. 1237-1252
    • Jee, M.K.1    Jung, J.S.2    Choi, J.I.3    Jang, J.A.4    Kang, K.S.5    Im, Y.B.6
  • 79
    • 84861749734 scopus 로고    scopus 로고
    • Silencing of miR20a is crucial for Ngn1-mediated neuroprotection in injured spinal cord
    • doi: 10.1089/hum.2011.121
    • Jee, M. K., Jung, J. S., Im, Y. B., Jung, S. J., and Kang, S. K. (2012b). Silencing of miR20a is crucial for Ngn1-mediated neuroprotection in injured spinal cord. Hum. Gene Ther. 23, 508-520. doi: 10.1089/hum.2011.121
    • (2012) Hum. Gene Ther. , vol.23 , pp. 508-520
    • Jee, M.K.1    Jung, J.S.2    Im, Y.B.3    Jung, S.J.4    Kang, S.K.5
  • 80
    • 41249102422 scopus 로고    scopus 로고
    • MicroRNA expression in the blood and brain of rats subjected to transient focal ischemia by middle cerebral artery occlusion
    • doi: 10.1161/STROKEAHA.107.500736
    • Jeyaseelan, K., Lim, K. Y., and Armugam, A. (2008). MicroRNA expression in the blood and brain of rats subjected to transient focal ischemia by middle cerebral artery occlusion. Stroke 39, 959-966. doi: 10.1161/STROKEAHA.107.500736
    • (2008) Stroke , vol.39 , pp. 959-966
    • Jeyaseelan, K.1    Lim, K.Y.2    Armugam, A.3
  • 81
    • 84859564436 scopus 로고    scopus 로고
    • Oxidative stress in spinal cord injury and antioxidant-based intervention
    • doi: 10.1038/sc.2011.111
    • Jia, Z., Zhu, H., Li, J., Wang, X., Misra, H., and Li, Y. (2012). Oxidative stress in spinal cord injury and antioxidant-based intervention. Spinal Cord 50, 264-274. doi: 10.1038/sc.2011.111
    • (2012) Spinal Cord , vol.50 , pp. 264-274
    • Jia, Z.1    Zhu, H.2    Li, J.3    Wang, X.4    Misra, H.5    Li, Y.6
  • 82
    • 16244384670 scopus 로고    scopus 로고
    • Inflammatory-mediated injury and repair in the traumatically injured spinal cord
    • doi: 10.2174/1381612053507468
    • Jones, T. B., McDaniel, E. E., and Popovich, P. G. (2005). Inflammatory-mediated injury and repair in the traumatically injured spinal cord. Curr. Pharm. Des. 11, 1223-1236. doi: 10.2174/1381612053507468
    • (2005) Curr. Pharm. Des. , vol.11 , pp. 1223-1236
    • Jones, T.B.1    McDaniel, E.E.2    Popovich, P.G.3
  • 83
    • 72649095061 scopus 로고    scopus 로고
    • MicroRNA profiling of multiple sclerosis lesions identifies modulators of the regulatory protein CD47
    • doi: 10.1093/brain/awp300
    • Junker, A., Krumbholz, M., Eisele, S., Mohan, H., Augstein, F., Bittner, R., et al. (2009). MicroRNA profiling of multiple sclerosis lesions identifies modulators of the regulatory protein CD47. Brain 132, 3342-3352. doi: 10.1093/brain/awp300
    • (2009) Brain , vol.132 , pp. 3342-3352
    • Junker, A.1    Krumbholz, M.2    Eisele, S.3    Mohan, H.4    Augstein, F.5    Bittner, R.6
  • 84
    • 84859738818 scopus 로고    scopus 로고
    • MicroRNAs in neurotoxicity
    • doi: 10.1155/2012/870150
    • Kaur, P., Armugam, A., and Jeyaseelan, K. (2012). MicroRNAs in neurotoxicity. J. Toxicol. 2012, 870150. doi: 10.1155/2012/870150
    • (2012) J. Toxicol. , vol.2012 , pp. 870150
    • Kaur, P.1    Armugam, A.2    Jeyaseelan, K.3
  • 85
    • 63249099917 scopus 로고    scopus 로고
    • Functional links between clustered microRNAs: Suppression of cell-cycle inhibitors by microRNA clusters in gastric cancer
    • doi: 10.1093/nar/gkp002
    • Kim, Y. K., Yu, J., Han, T. S., Park, S. Y., Namkoong, B., Kim, D. H., et al. (2009). Functional links between clustered microRNAs: suppression of cell-cycle inhibitors by microRNA clusters in gastric cancer. Nucleic Acids Res. 37, 1672-1681. doi: 10.1093/nar/gkp002
    • (2009) Nucleic Acids Res. , vol.37 , pp. 1672-1681
    • Kim, Y.K.1    Yu, J.2    Han, T.S.3    Park, S.Y.4    Namkoong, B.5    Kim, D.H.6
  • 86
    • 80052360838 scopus 로고    scopus 로고
    • Haemolysis during sample preparation alters microRNA content of plasma
    • doi: 10.1371/journal.pone.0024145
    • Kirschner, M. B., Kao, S. C., Edelman, J. J., Armstrong, N. J., Vallely, M. P., van Zandwijk, N., et al. (2011). Haemolysis during sample preparation alters microRNA content of plasma. PLoS ONE 6:e24145. doi: 10.1371/journal.pone.0024145
    • (2011) PLoS ONE , vol.6
    • Kirschner, M.B.1    Kao, S.C.2    Edelman, J.J.3    Armstrong, N.J.4    Vallely, M.P.5    van Zandwijk, N.6
  • 87
    • 77957091969 scopus 로고    scopus 로고
    • Circulating microRNA in body fluid: A new potential biomarker for cancer diagnosis and prognosis
    • doi: 10.1111/j.1349-7006.2010.01650.x
    • Kosaka, N., Iguchi, H., and Ochiya, T. (2010). Circulating microRNA in body fluid: a new potential biomarker for cancer diagnosis and prognosis. Cancer Sci. 101, 2087-2092. doi: 10.1111/j.1349-7006.2010.01650.x
    • (2010) Cancer Sci. , vol.101 , pp. 2087-2092
    • Kosaka, N.1    Iguchi, H.2    Ochiya, T.3
  • 88
    • 33751254116 scopus 로고    scopus 로고
    • The neuronal microRNA system
    • doi: 10.1038/nrn2037
    • Kosik, K. S. (2006). The neuronal microRNA system. Nat. Rev. Neurosci. 7, 911-920. doi: 10.1038/nrn2037
    • (2006) Nat. Rev. Neurosci. , vol.7 , pp. 911-920
    • Kosik, K.S.1
  • 89
    • 77957226018 scopus 로고    scopus 로고
    • MicroRNAs and cellular phenotypy
    • doi: 10.1016/j.cell.2010.09.008
    • Kosik, K. S. (2010). MicroRNAs and cellular phenotypy. Cell 143, 21-26. doi: 10.1016/j.cell.2010.09.008
    • (2010) Cell , vol.143 , pp. 21-26
    • Kosik, K.S.1
  • 90
    • 78651293534 scopus 로고    scopus 로고
    • MiRBase: Integrating microRNA annotation and deep-sequencing data
    • doi: 10.1093/nar/gkq1027
    • Kozomara, A., and Griffiths-Jones, S. (2011). miRBase: integrating microRNA annotation and deep-sequencing data. Nucleic Acids Res. 39, D152-D157. doi: 10.1093/nar/gkq1027
    • (2011) Nucleic Acids Res. , vol.39
    • Kozomara, A.1    Griffiths-Jones, S.2
  • 91
    • 20944450160 scopus 로고    scopus 로고
    • Combinatorial microRNA target predictions
    • doi: 10.1038/ng1536
    • Krek, A., Grun, D., Poy, M. N., Wolf, R., Rosenberg, L., Epstein, E. J., et al. (2005). Combinatorial microRNA target predictions. Nat. Genet. 37, 495-500. doi: 10.1038/ng1536
    • (2005) Nat. Genet. , vol.37 , pp. 495-500
    • Krek, A.1    Grun, D.2    Poy, M.N.3    Wolf, R.4    Rosenberg, L.5    Epstein, E.J.6
  • 92
    • 37249042389 scopus 로고    scopus 로고
    • MicroRNA profiling: From dark matter to white matter, or identifying new players in neurobiology
    • doi: 10.1100/tsw.2007.201
    • Krichevsky, A. M. (2007). MicroRNA profiling: from dark matter to white matter, or identifying new players in neurobiology. ScientificWorldJournal 7, 155-166. doi: 10.1100/tsw.2007.201
    • (2007) ScientificWorldJournal , vol.7 , pp. 155-166
    • Krichevsky, A.M.1
  • 93
    • 0141631876 scopus 로고    scopus 로고
    • A microRNA array reveals extensive regulation of microRNAs during brain development
    • doi: 10.1261/rna.5980303
    • Krichevsky, A. M., King, K. S., Donahue, C. P., Khrapko, K., and Kosik, K. S. (2003). A microRNA array reveals extensive regulation of microRNAs during brain development. RNA 9, 1274-1281. doi: 10.1261/rna.5980303
    • (2003) RNA , vol.9 , pp. 1274-1281
    • Krichevsky, A.M.1    King, K.S.2    Donahue, C.P.3    Khrapko, K.4    Kosik, K.S.5
  • 94
    • 33745480963 scopus 로고    scopus 로고
    • Specific microRNAs modulate embryonic stem cell-derived neurogenesis
    • doi: 10.1634/stemcells.2005-0441
    • Krichevsky, A. M., Sonntag, K. C., Isacson, O., and Kosik, K. S. (2006). Specific microRNAs modulate embryonic stem cell-derived neurogenesis. Stem Cells 24, 857-864. doi: 10.1634/stemcells.2005-0441
    • (2006) Stem Cells , vol.24 , pp. 857-864
    • Krichevsky, A.M.1    Sonntag, K.C.2    Isacson, O.3    Kosik, K.S.4
  • 95
    • 77955902024 scopus 로고    scopus 로고
    • The widespread regulation of microRNA biogenesis, function and decay
    • doi: 10.1038/nrg2843
    • Krol, J., Loedige, I., and Filipowicz, W. (2010). The widespread regulation of microRNA biogenesis, function and decay. Nat. Rev. Genet. 11, 597-610. doi: 10.1038/nrg2843
    • (2010) Nat. Rev. Genet. , vol.11 , pp. 597-610
    • Krol, J.1    Loedige, I.2    Filipowicz, W.3
  • 96
    • 79952329706 scopus 로고    scopus 로고
    • Differential expression of microRNAs in mouse pain models
    • doi: 10.1186/1744-8069-7-17
    • Kusuda, R., Cadetti, F., Ravanelli, M. I., Sousa, T. A., Zanon, S., De Lucca, F. L., et al. (2011). Differential expression of microRNAs in mouse pain models. Mol. Pain 7, 17. doi: 10.1186/1744-8069-7-17
    • (2011) Mol. Pain , vol.7 , pp. 17
    • Kusuda, R.1    Cadetti, F.2    Ravanelli, M.I.3    Sousa, T.A.4    Zanon, S.5    De Lucca, F.L.6
  • 97
    • 70449709341 scopus 로고    scopus 로고
    • Plasma MicroRNAs as sensitive and specific biomarkers of tissue injury
    • doi: 10.1373/clinchem.2009.131797
    • Laterza, O. F., Lim, L., Garrett-Engele, P. W., Vlasakova, K., Muniappa, N., Tanaka, W. K., et al. (2009). Plasma MicroRNAs as sensitive and specific biomarkers of tissue injury. Clin. Chem. 55, 1977-1983. doi: 10.1373/clinchem.2009.131797
    • (2009) Clin. Chem. , vol.55 , pp. 1977-1983
    • Laterza, O.F.1    Lim, L.2    Garrett-Engele, P.W.3    Vlasakova, K.4    Muniappa, N.5    Tanaka, W.K.6
  • 98
    • 58149233779 scopus 로고    scopus 로고
    • Identification of dynamically regulated microRNA and mRNA networks in developing oligodendrocytes
    • doi: 10.1523/JNEUROSCI.1932-08.2008
    • Lau, P., Verrier, J. D., Nielsen, J. A., Johnson, K. R., Notterpek, L., and Hudson, L. D. (2008). Identification of dynamically regulated microRNA and mRNA networks in developing oligodendrocytes. J. Neurosci. 28, 11720-11730. doi: 10.1523/JNEUROSCI.1932-08.2008
    • (2008) J. Neurosci. , vol.28 , pp. 11720-11730
    • Lau, P.1    Verrier, J.D.2    Nielsen, J.A.3    Johnson, K.R.4    Notterpek, L.5    Hudson, L.D.6
  • 99
    • 84893859636 scopus 로고    scopus 로고
    • The global map for traumatic spinal cord injury epidemiology: Update 2011, global incidence rate
    • doi: 10.1038/sc.2012.158
    • Lee, B. B., Cripps, R. A., Fitzharris, M., and Wing, P. C. (2013). The global map for traumatic spinal cord injury epidemiology: update 2011, global incidence rate. Spinal Cord 110-116. doi: 10.1038/sc.2012.158
    • (2013) Spinal Cord , pp. 110-116
    • Lee, B.B.1    Cripps, R.A.2    Fitzharris, M.3    Wing, P.C.4
  • 100
    • 38049046644 scopus 로고    scopus 로고
    • Systematic evaluation of microRNA processing patterns in tissues, cell lines, and tumors
    • doi: 10.1261/rna.804508
    • Lee, E. J., Baek, M., Gusev, Y., Brackett, D. J., Nuovo, G. J., and Schmittgen, T. D. (2008). Systematic evaluation of microRNA processing patterns in tissues, cell lines, and tumors. RNA 14, 35-42. doi: 10.1261/rna.804508
    • (2008) RNA , vol.14 , pp. 35-42
    • Lee, E.J.1    Baek, M.2    Gusev, Y.3    Brackett, D.J.4    Nuovo, G.J.5    Schmittgen, T.D.6
  • 101
    • 0027751663 scopus 로고
    • The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14
    • doi: 10.1016/0092-8674(93)90529-Y
    • Lee, R. C., Feinbaum, R. L., and Ambros, V. (1993). The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14. Cell 75, 843-854. doi: 10.1016/0092-8674(93)90529-Y
    • (1993) Cell , vol.75 , pp. 843-854
    • Lee, R.C.1    Feinbaum, R.L.2    Ambros, V.3
  • 102
    • 84859590519 scopus 로고    scopus 로고
    • Cell-free seminal mRNA and microRNA exist in different forms
    • doi: 10.1371/journal.pone.0034566
    • Li, H., Huang, S., Guo, C., Guan, H., and Xiong, C. (2012). Cell-free seminal mRNA and microRNA exist in different forms. PLoS ONE 7:e34566. doi: 10.1371/journal.pone.0034566
    • (2012) PLoS ONE , vol.7
    • Li, H.1    Huang, S.2    Guo, C.3    Guan, H.4    Xiong, C.5
  • 103
    • 84878233925 scopus 로고    scopus 로고
    • Differential expression of miRNAs in the nervous system of a rat model of bilateral sciatic nerve chronic constriction injury
    • doi: 10.3892/ijmm.2013.1381
    • Li, H., Shen, L., Ma, C., and Huang, Y. (2013). Differential expression of miRNAs in the nervous system of a rat model of bilateral sciatic nerve chronic constriction injury. Int. J. Mol. Med. 32, 219-226. doi: 10.3892/ijmm.2013.1381
    • (2013) Int. J. Mol. Med. , vol.32 , pp. 219-226
    • Li, H.1    Shen, L.2    Ma, C.3    Huang, Y.4
  • 104
    • 77951499826 scopus 로고    scopus 로고
    • Roles of small regulatory RNAs in determining neuronal identity
    • doi: 10.1038/nrn2739
    • Li, X., and Jin, P. (2010). Roles of small regulatory RNAs in determining neuronal identity. Nat. Rev. Neurosci. 11, 329-338. doi: 10.1038/nrn2739
    • (2010) Nat. Rev. Neurosci. , vol.11 , pp. 329-338
    • Li, X.1    Jin, P.2
  • 105
    • 13944282215 scopus 로고    scopus 로고
    • Microarray analysis shows that some microRNAs downregulate large numbers of target mRNAs
    • doi: 10.1038/nature03315
    • Lim, L. P., Lau, N. C., Garrett-Engele, P., Grimson, A., Schelter, J. M., Castle, J., et al. (2005). Microarray analysis shows that some microRNAs downregulate large numbers of target mRNAs. Nature 433, 769-773. doi: 10.1038/nature03315
    • (2005) Nature , vol.433 , pp. 769-773
    • Lim, L.P.1    Lau, N.C.2    Garrett-Engele, P.3    Grimson, A.4    Schelter, J.M.5    Castle, J.6
  • 106
    • 45549103746 scopus 로고    scopus 로고
    • MicroRNAs and the immune response
    • doi: 10.1016/j.it.2008.04.004
    • Lindsay, M. A. (2008). microRNAs and the immune response. Trends Immunol. 29, 343-351. doi: 10.1016/j.it.2008.04.004
    • (2008) Trends Immunol. , vol.29 , pp. 343-351
    • Lindsay, M.A.1
  • 107
    • 69749105831 scopus 로고    scopus 로고
    • Altered microRNA expression following traumatic spinal cord injury
    • doi: 10.1016/j.expneurol.2009.06.015
    • Liu, N. K., Wang, X. F., Lu, Q. B., and Xu, X. M. (2009). Altered microRNA expression following traumatic spinal cord injury. Exp. Neurol. 219, 424-429. doi: 10.1016/j.expneurol.2009.06.015
    • (2009) Exp. Neurol. , vol.219 , pp. 424-429
    • Liu, N.K.1    Wang, X.F.2    Lu, Q.B.3    Xu, X.M.4
  • 108
    • 16944363478 scopus 로고    scopus 로고
    • Neuronal and glial apoptosis after traumatic spinal cord injury
    • Liu, X. Z., Xu, X. M., Hu, R., Du, C., Zhang, S. X., McDonald, J. W., et al. (1997). Neuronal and glial apoptosis after traumatic spinal cord injury. J. Neurosci. 17, 5395-5406.
    • (1997) J. Neurosci. , vol.17 , pp. 5395-5406
    • Liu, X.Z.1    Xu, X.M.2    Hu, R.3    Du, C.4    Zhang, S.X.5    McDonald, J.W.6
  • 109
    • 79958099199 scopus 로고    scopus 로고
    • MicroRNA-98 negatively regulates IL-10 production and endotoxin tolerance in macrophages after LPS stimulation
    • doi: 10.1016/j.febslet.2011.05.029
    • Liu, Y., Chen, Q., Song, Y., Lai, L., Wang, J., Yu, H., et al. (2011). MicroRNA-98 negatively regulates IL-10 production and endotoxin tolerance in macrophages after LPS stimulation. FEBS Lett. 585, 1963-1968. doi: 10.1016/j.febslet.2011.05.029
    • (2011) FEBS Lett. , vol.585 , pp. 1963-1968
    • Liu, Y.1    Chen, Q.2    Song, Y.3    Lai, L.4    Wang, J.5    Yu, H.6
  • 111
    • 20444460289 scopus 로고    scopus 로고
    • MicroRNA expression profiles classify human cancers
    • doi: 10.1038/nature03702
    • Lu, J., Getz, G., Miska, E. A., Alvarez-Saavedra, E., Lamb, J., Peck, D., et al. (2005). MicroRNA expression profiles classify human cancers. Nature 435, 834-838. doi: 10.1038/nature03702
    • (2005) Nature , vol.435 , pp. 834-838
    • Lu, J.1    Getz, G.2    Miska, E.A.3    Alvarez-Saavedra, E.4    Lamb, J.5    Peck, D.6
  • 112
    • 0042838315 scopus 로고    scopus 로고
    • Expression deconvolution: A reinterpretation of DNA microarray data reveals dynamic changes in cell populations
    • doi: 10.1073/pnas.1832361100
    • Lu, P., Nakorchevskiy, A., and Marcotte, E. M. (2003). Expression deconvolution: a reinterpretation of DNA microarray data reveals dynamic changes in cell populations. Proc. Natl. Acad. Sci. U.S.A. 100, 10370-10375. doi: 10.1073/pnas.1832361100
    • (2003) Proc. Natl. Acad. Sci. U.S.A. , vol.100 , pp. 10370-10375
    • Lu, P.1    Nakorchevskiy, A.2    Marcotte, E.M.3
  • 114
    • 34547212309 scopus 로고    scopus 로고
    • The MicroRNA miR-124 promotes neuronal differentiation by triggering brain-specific alternative pre-mRNA splicing
    • doi: 10.1016/j.molcel.2007.07.015
    • Makeyev, E. V., Zhang, J., Carrasco, M. A., and Maniatis, T. (2007). The MicroRNA miR-124 promotes neuronal differentiation by triggering brain-specific alternative pre-mRNA splicing. Mol. Cell 27, 435-448. doi: 10.1016/j.molcel.2007.07.015
    • (2007) Mol. Cell , vol.27 , pp. 435-448
    • Makeyev, E.V.1    Zhang, J.2    Carrasco, M.A.3    Maniatis, T.4
  • 115
    • 84881541611 scopus 로고    scopus 로고
    • Burden of spinal cord injury-related neuropathic pain in the United States: Retrospective chart review and cross-sectional survey
    • doi: 10.1038/sc.2013.34
    • Mann, R., Schaefer, C., Sadosky, A., Bergstrom, F., Baik, R., Parsons, B., et al. (2013). Burden of spinal cord injury-related neuropathic pain in the United States: retrospective chart review and cross-sectional survey. Spinal Cord 51, 564-570. doi: 10.1038/sc.2013.34
    • (2013) Spinal Cord , vol.51 , pp. 564-570
    • Mann, R.1    Schaefer, C.2    Sadosky, A.3    Bergstrom, F.4    Baik, R.5    Parsons, B.6
  • 116
    • 0033920448 scopus 로고    scopus 로고
    • Vascular events after spinal cord injury: Contribution to secondary pathogenesis
    • Mautes, A. E., Weinzierl, M. R., Donovan, F., and Noble, L. J. (2000). Vascular events after spinal cord injury: contribution to secondary pathogenesis. Phys. Ther. 80, 673-687.
    • (2000) Phys. Ther. , vol.80 , pp. 673-687
    • Mautes, A.E.1    Weinzierl, M.R.2    Donovan, F.3    Noble, L.J.4
  • 117
    • 0034110049 scopus 로고    scopus 로고
    • Localization of transforming growth factor-beta1 and receptor mRNA after experimental spinal cord injury
    • doi: 10.1006/exnr.2000.7372
    • McTigue, D. M., Popovich, P. G., Morgan, T. E., and Stokes, B. T. (2000). Localization of transforming growth factor-beta1 and receptor mRNA after experimental spinal cord injury. Exp. Neurol. 163, 220-230. doi: 10.1006/exnr.2000.7372
    • (2000) Exp. Neurol. , vol.163 , pp. 220-230
    • McTigue, D.M.1    Popovich, P.G.2    Morgan, T.E.3    Stokes, B.T.4
  • 118
    • 51649111487 scopus 로고    scopus 로고
    • Differential expression of microRNAs in hematopoietic cell lineages
    • doi: 10.1111/j.1600-0609.2008.01111.x
    • Merkerova, M., Belickova, M., and Bruchova, H. (2008). Differential expression of microRNAs in hematopoietic cell lineages. Eur. J. Haematol. 81, 304-310. doi: 10.1111/j.1600-0609.2008.01111.x
    • (2008) Eur. J. Haematol. , vol.81 , pp. 304-310
    • Merkerova, M.1    Belickova, M.2    Bruchova, H.3
  • 119
    • 78649941638 scopus 로고    scopus 로고
    • The miR-17-92 microRNA cluster regulates multiple components of the TGF-β pathway in neuroblastoma
    • doi: 10.1016/j.molcel.2010.11.038
    • Mestdagh, P., Bostrom, A. K., Impens, F., Fredlund, E., Van Peer, G., De Antonellis, P., et al. (2010). The miR-17-92 microRNA cluster regulates multiple components of the TGF-β pathway in neuroblastoma. Mol. Cell 40, 762-773. doi: 10.1016/j.molcel.2010.11.038
    • (2010) Mol. Cell , vol.40 , pp. 762-773
    • Mestdagh, P.1    Bostrom, A.K.2    Impens, F.3    Fredlund, E.4    Van Peer, G.5    De Antonellis, P.6
  • 120
    • 81255185503 scopus 로고    scopus 로고
    • Role of microRNAs in central nervous system development and pathology
    • doi: 10.1002/jnr.22701
    • Meza-Sosa, K. F., Valle-Garcia, D., Pedraza-Alva, G., and Perez-Martinez, L. (2012). Role of microRNAs in central nervous system development and pathology. J. Neurosci. Res. 90, 1-12. doi: 10.1002/jnr.22701
    • (2012) J. Neurosci. Res. , vol.90 , pp. 1-12
    • Meza-Sosa, K.F.1    Valle-Garcia, D.2    Pedraza-Alva, G.3    Perez-Martinez, L.4
  • 121
    • 5344273958 scopus 로고    scopus 로고
    • Microarray analysis of microRNA expression in the developing mammalian brain
    • doi: 10.1186/gb-2004-5-9-r68
    • Miska, E. A., Alvarez-Saavedra, E., Townsend, M., Yoshii, A., Sestan, N., Rakic, P., et al. (2004). Microarray analysis of microRNA expression in the developing mammalian brain. Genome Biol. 5, R68. doi: 10.1186/gb-2004-5-9-r68
    • (2004) Genome Biol. , vol.5
    • Miska, E.A.1    Alvarez-Saavedra, E.2    Townsend, M.3    Yoshii, A.4    Sestan, N.5    Rakic, P.6
  • 122
    • 84874833693 scopus 로고    scopus 로고
    • Neuronal exosomal miRNA-dependent translational regulation of astroglial glutamate transporter GLT1
    • doi: 10.1074/jbc.M112.410944
    • Morel, L., Regan, M., Higashimori, H., Ng, S. K., Esau, C., Vidensky, S., et al. (2013). Neuronal exosomal miRNA-dependent translational regulation of astroglial glutamate transporter GLT1. J. Biol. Chem. 288, 7105-7116. doi: 10.1074/jbc.M112.410944
    • (2013) J. Biol. Chem. , vol.288 , pp. 7105-7116
    • Morel, L.1    Regan, M.2    Higashimori, H.3    Ng, S.K.4    Esau, C.5    Vidensky, S.6
  • 123
    • 77949269036 scopus 로고    scopus 로고
    • Responses of microRNAs 124a and 223 following spinal cord injury in mice
    • doi: 10.1038/sc.2009.89
    • Nakanishi, K., Nakasa, T., Tanaka, N., Ishikawa, M., Yamada, K., Yamasaki, K., et al. (2010). Responses of microRNAs 124a and 223 following spinal cord injury in mice. Spinal Cord 48, 192-196. doi: 10.1038/sc.2009.89
    • (2010) Spinal Cord , vol.48 , pp. 192-196
    • Nakanishi, K.1    Nakasa, T.2    Tanaka, N.3    Ishikawa, M.4    Yamada, K.5    Yamasaki, K.6
  • 124
    • 79960102657 scopus 로고    scopus 로고
    • Secondary injury mechanisms in traumatic spinal cord injury: A nugget of this multiply cascade
    • Oyinbo, C. A. (2011). Secondary injury mechanisms in traumatic spinal cord injury: a nugget of this multiply cascade. Acta Neurobiol. Exp. (Wars) 71, 281-299.
    • (2011) Acta Neurobiol. Exp. (Wars) , vol.71 , pp. 281-299
    • Oyinbo, C.A.1
  • 125
    • 7944223409 scopus 로고    scopus 로고
    • Astrocyte intermediate filaments in CNS pathologies and regeneration
    • doi: 10.1002/path.1645
    • Pekny, M., and Pekna, M. (2004). Astrocyte intermediate filaments in CNS pathologies and regeneration. J. Pathol. 204, 428-437. doi: 10.1002/path.1645
    • (2004) J. Pathol. , vol.204 , pp. 428-437
    • Pekny, M.1    Pekna, M.2
  • 126
    • 83455225035 scopus 로고    scopus 로고
    • MicroRNA modulation in obesity and periodontitis
    • doi: 10.1177/0022034511425045
    • Perri, R., Nares, S., Zhang, S., Barros, S. P., and Offenbacher, S. (2012). MicroRNA modulation in obesity and periodontitis. J. Dent. Res. 91, 33-38. doi: 10.1177/0022034511425045
    • (2012) J. Dent. Res. , vol.91 , pp. 33-38
    • Perri, R.1    Nares, S.2    Zhang, S.3    Barros, S.P.4    Offenbacher, S.5
  • 127
    • 77952745811 scopus 로고    scopus 로고
    • Micro RNA-125b (miRNA-125b) function in astrogliosis and glial cell proliferation
    • doi: 10.1016/j.neulet.2010.03.054
    • Pogue, A. I., Cui, J. G., Li, Y. Y., Zhao, Y., Culicchia, F., and Lukiw, W. J. (2010). Micro RNA-125b (miRNA-125b) function in astrogliosis and glial cell proliferation. Neurosci. Lett. 476, 18-22. doi: 10.1016/j.neulet.2010.03.054
    • (2010) Neurosci. Lett. , vol.476 , pp. 18-22
    • Pogue, A.I.1    Cui, J.G.2    Li, Y.Y.3    Zhao, Y.4    Culicchia, F.5    Lukiw, W.J.6
  • 128
    • 78651247933 scopus 로고    scopus 로고
    • MicroRNA-124 promotes microglia quiescence and suppresses EAE by deactivating macrophages via the C/EBP-alpha-PU.1 pathway
    • doi: 10.1038/nm.2266
    • Ponomarev, E. D., Veremeyko, T., Barteneva, N., Krichevsky, A. M., and Weiner, H. L. (2011). MicroRNA-124 promotes microglia quiescence and suppresses EAE by deactivating macrophages via the C/EBP-alpha-PU.1 pathway. Nat. Med. 17, 64-70. doi: 10.1038/nm.2266
    • (2011) Nat. Med. , vol.17 , pp. 64-70
    • Ponomarev, E.D.1    Veremeyko, T.2    Barteneva, N.3    Krichevsky, A.M.4    Weiner, H.L.5
  • 129
    • 84859892863 scopus 로고    scopus 로고
    • MicroRNA profiling: Approaches and considerations
    • doi: 10.1038/nrg3198
    • Pritchard, C. C., Cheng, H. H., and Tewari, M. (2012). MicroRNA profiling: approaches and considerations. Nat. Rev. Genet. 13, 358-369. doi: 10.1038/nrg3198
    • (2012) Nat. Rev. Genet. , vol.13 , pp. 358-369
    • Pritchard, C.C.1    Cheng, H.H.2    Tewari, M.3
  • 130
    • 1842419475 scopus 로고    scopus 로고
    • Degenerative and regenerative mechanisms governing spinal cord injury
    • doi: 10.1016/j.nbd.2003.11.015
    • Profyris, C., Cheema, S. S., Zang, D., Azari, M. F., Boyle, K., and Petratos, S. (2004). Degenerative and regenerative mechanisms governing spinal cord injury. Neurobiol. Dis. 15, 415-436. doi: 10.1016/j.nbd.2003.11.015
    • (2004) Neurobiol. Dis. , vol.15 , pp. 415-436
    • Profyris, C.1    Cheema, S.S.2    Zang, D.3    Azari, M.F.4    Boyle, K.5    Petratos, S.6
  • 131
    • 0034746732 scopus 로고    scopus 로고
    • Bcl-xL expression after contusion to the rat spinal cord
    • doi: 10.1089/089771501317095304
    • Qiu, J., Nesic, O., Ye, Z., Rea, H., Westlund, K. N., Xu, G. Y., et al. (2001). Bcl-xL expression after contusion to the rat spinal cord. J. Neurotrauma 18, 1267-1278. doi: 10.1089/089771501317095304
    • (2001) J. Neurotrauma , vol.18 , pp. 1267-1278
    • Qiu, J.1    Nesic, O.2    Ye, Z.3    Rea, H.4    Westlund, K.N.5    Xu, G.Y.6
  • 132
    • 78650089702 scopus 로고    scopus 로고
    • Human traumatic brain injury alters plasma microRNA levels
    • doi: 10.1089/neu.2010.1481
    • Redell, J. B., Moore, A. N., Ward, N. H. III, Hergenroeder, G. W., and Dash, P. K. (2010). Human traumatic brain injury alters plasma microRNA levels. J. Neurotrauma 27, 2147-2156. doi: 10.1089/neu.2010.1481
    • (2010) J. Neurotrauma , vol.27 , pp. 2147-2156
    • Redell, J.B.1    Moore, A.N.2    Ward III, N.H.3    Hergenroeder, G.W.4    Dash, P.K.5
  • 133
    • 63849340879 scopus 로고    scopus 로고
    • Current status of acute spinal cord injury pathophysiology and emerging therapies: Promise on the horizon
    • doi: 10.3171/FOC.2008.25.11.E2
    • Rowland, J. W., Hawryluk, G. W., Kwon, B., and Fehlings, M. G. (2008). Current status of acute spinal cord injury pathophysiology and emerging therapies: promise on the horizon. Neurosurg. Focus 25, E2. doi: 10.3171/FOC.2008.25.11.E2
    • (2008) Neurosurg. Focus , vol.25
    • Rowland, J.W.1    Hawryluk, G.W.2    Kwon, B.3    Fehlings, M.G.4
  • 134
    • 76149085535 scopus 로고    scopus 로고
    • BMPR1a and BMPR1b signaling exert opposing effects on gliosis after spinal cord injury
    • doi: 10.1523/JNEUROSCI.4459-09.2010
    • Sahni, V., Mukhopadhyay, A., Tysseling, V., Hebert, A., Birch, D., McGuire, T. L., et al. (2010). BMPR1a and BMPR1b signaling exert opposing effects on gliosis after spinal cord injury. J. Neurosci. 30, 1839-1855. doi: 10.1523/JNEUROSCI.4459-09.2010
    • (2010) J. Neurosci. , vol.30 , pp. 1839-1855
    • Sahni, V.1    Mukhopadhyay, A.2    Tysseling, V.3    Hebert, A.4    Birch, D.5    McGuire, T.L.6
  • 135
    • 0033994463 scopus 로고    scopus 로고
    • Implications of p53 protein expression in experimental spinal cord injury
    • doi: 10.1089/neu.2000.17.173
    • Saito, N., Yamamoto, T., Watanabe, T., Abe, Y., and Kumagai, T. (2000). Implications of p53 protein expression in experimental spinal cord injury. J. Neurotrauma 17, 173-182. doi: 10.1089/neu.2000.17.173
    • (2000) J. Neurotrauma , vol.17 , pp. 173-182
    • Saito, N.1    Yamamoto, T.2    Watanabe, T.3    Abe, Y.4    Kumagai, T.5
  • 136
    • 33744805399 scopus 로고    scopus 로고
    • Specific activation of microRNA-127 with downregulation of the proto-oncogene BCL6 by chromatin-modifying drugs in human cancer cells
    • doi: 10.1016/j.ccr.2006.04.020
    • Saito, Y., Liang, G., Egger, G., Friedman, J. M., Chuang, J. C., Coetzee, G. A., et al. (2006). Specific activation of microRNA-127 with downregulation of the proto-oncogene BCL6 by chromatin-modifying drugs in human cancer cells. Cancer Cell 9, 435-443. doi: 10.1016/j.ccr.2006.04.020
    • (2006) Cancer Cell , vol.9 , pp. 435-443
    • Saito, Y.1    Liang, G.2    Egger, G.3    Friedman, J.M.4    Chuang, J.C.5    Coetzee, G.A.6
  • 137
    • 0037072506 scopus 로고    scopus 로고
    • Lipid peroxidation by nitric oxide supplements after spinal cord injury: Effect of antioxidants in rats
    • doi: 10.1016/S0304-3940(02)00716-4
    • Santoscoy, C., Rios, C., Franco-Bourland, R. E., Hong, E., Bravo, G., Rojas, G., et al. (2002). Lipid peroxidation by nitric oxide supplements after spinal cord injury: effect of antioxidants in rats. Neurosci. Lett. 330, 94-98. doi: 10.1016/S0304-3940(02)00716-4
    • (2002) Neurosci. Lett. , vol.330 , pp. 94-98
    • Santoscoy, C.1    Rios, C.2    Franco-Bourland, R.E.3    Hong, E.4    Bravo, G.5    Rojas, G.6
  • 138
    • 77956263239 scopus 로고    scopus 로고
    • MicroRNAs as effectors of brain function with roles in ischemia and injury, neuroprotection, and neurodegeneration
    • doi: 10.1038/jcbfm.2010.101
    • Saugstad, J. A. (2010). MicroRNAs as effectors of brain function with roles in ischemia and injury, neuroprotection, and neurodegeneration. J. Cereb. Blood Flow Metab. 30, 1564-1576. doi: 10.1038/jcbfm.2010.101
    • (2010) J. Cereb. Blood Flow Metab. , vol.30 , pp. 1564-1576
    • Saugstad, J.A.1
  • 139
    • 84880262010 scopus 로고    scopus 로고
    • MicroRNAs as effectors of brain function
    • doi: 10.1161/STROKEAHA.113.000985
    • Saugstad, J. A. (2013). MicroRNAs as effectors of brain function. Stroke 44(Suppl. 1), S17-S19. doi: 10.1161/STROKEAHA.113.000985
    • (2013) Stroke , vol.44 , Issue.SUPPL. 1
    • Saugstad, J.A.1
  • 140
    • 79960104144 scopus 로고    scopus 로고
    • MicroRNAs in development and disease
    • doi: 10.1152/physrev.00006.2010
    • Sayed, D., and Abdellatif, M. (2011). MicroRNAs in development and disease. Physiol. Rev. 91, 827-887. doi: 10.1152/physrev.00006.2010
    • (2011) Physiol. Rev. , vol.91 , pp. 827-887
    • Sayed, D.1    Abdellatif, M.2
  • 141
    • 35548937457 scopus 로고    scopus 로고
    • The neuropathic pain triad: Neurons, immune cells and glia
    • doi: 10.1038/nn1992
    • Scholz, J., and Woolf, C. J. (2007). The neuropathic pain triad: neurons, immune cells and glia. Nat. Neurosci. 10, 1361-1368. doi: 10.1038/nn1992
    • (2007) Nat. Neurosci. , vol.10 , pp. 1361-1368
    • Scholz, J.1    Woolf, C.J.2
  • 142
    • 49949117302 scopus 로고    scopus 로고
    • Widespread changes in protein synthesis induced by microRNAs
    • doi: 10.1038/nature07228
    • Selbach, M., Schwanhausser, B., Thierfelder, N., Fang, Z., Khanin, R., and Rajewsky, N. (2008). Widespread changes in protein synthesis induced by microRNAs. Nature 455, 58-63. doi: 10.1038/nature07228
    • (2008) Nature , vol.455 , pp. 58-63
    • Selbach, M.1    Schwanhausser, B.2    Thierfelder, N.3    Fang, Z.4    Khanin, R.5    Rajewsky, N.6
  • 143
    • 1942494040 scopus 로고    scopus 로고
    • Expression profiling of mammalian microRNAs uncovers a subset of brain-expressed microRNAs with possible roles in murine and human neuronal differentiation
    • doi: 10.1186/gb-2004-5-3-r13
    • Sempere, L. F., Freemantle, S., Pitha-Rowe, I., Moss, E., Dmitrovsky, E., and Ambros, V. (2004). Expression profiling of mammalian microRNAs uncovers a subset of brain-expressed microRNAs with possible roles in murine and human neuronal differentiation. Genome Biol. 5, R13. doi: 10.1186/gb-2004-5-3-r13
    • (2004) Genome Biol. , vol.5
    • Sempere, L.F.1    Freemantle, S.2    Pitha-Rowe, I.3    Moss, E.4    Dmitrovsky, E.5    Ambros, V.6
  • 144
    • 65249155995 scopus 로고    scopus 로고
    • Posttranscriptional regulation of interleukin-10 expression by hsa-miR-106a
    • doi: 10.1073/pnas.0808743106
    • Sharma, A., Kumar, M., Aich, J., Hariharan, M., Brahmachari, S. K., Agrawal, A., et al. (2009). Posttranscriptional regulation of interleukin-10 expression by hsa-miR-106a. Proc. Natl. Acad. Sci. U.S.A. 106, 5761-5766. doi: 10.1073/pnas.0808743106
    • (2009) Proc. Natl. Acad. Sci. U.S.A. , vol.106 , pp. 5761-5766
    • Sharma, A.1    Kumar, M.2    Aich, J.3    Hariharan, M.4    Brahmachari, S.K.5    Agrawal, A.6
  • 145
    • 75649113377 scopus 로고    scopus 로고
    • Negative regulation of TLR4 via targeting of the proinflammatory tumor suppressor PDCD4 by the microRNA miR-21
    • doi: 10.1038/ni.1828
    • Sheedy, F. J., Palsson-McDermott, E., Hennessy, E. J., Martin, C., O'Leary, J. J., Ruan, Q., et al. (2010). Negative regulation of TLR4 via targeting of the proinflammatory tumor suppressor PDCD4 by the microRNA miR-21. Nat. Immunol. 11, 141-147. doi: 10.1038/ni.1828
    • (2010) Nat. Immunol. , vol.11 , pp. 141-147
    • Sheedy, F.J.1    Palsson-McDermott, E.2    Hennessy, E.J.3    Martin, C.4    O'Leary, J.J.5    Ruan, Q.6
  • 146
    • 73549104488 scopus 로고    scopus 로고
    • Dicer ablation in oligodendrocytes provokes neuronal impairment in mice
    • doi: 10.1002/ana.21927
    • Shin, D., Shin, J. Y., McManus, M. T., Ptacek, L. J., and Fu, Y. H. (2009). Dicer ablation in oligodendrocytes provokes neuronal impairment in mice. Ann. Neurol. 66, 843-857. doi: 10.1002/ana.21927
    • (2009) Ann. Neurol. , vol.66 , pp. 843-857
    • Shin, D.1    Shin, J.Y.2    McManus, M.T.3    Ptacek, L.J.4    Fu, Y.H.5
  • 147
    • 79960743857 scopus 로고    scopus 로고
    • Genomewide microRNA down-regulation as a negative feedback mechanism in the early phases of liver regeneration
    • doi: 10.1002/hep.24421
    • Shu, J., Kren, B. T., Xia, Z., Wong, P. Y., Li, L., Hanse, E. A., et al. (2011). Genomewide microRNA down-regulation as a negative feedback mechanism in the early phases of liver regeneration. Hepatology 54, 609-619. doi: 10.1002/hep.24421
    • (2011) Hepatology , vol.54 , pp. 609-619
    • Shu, J.1    Kren, B.T.2    Xia, Z.3    Wong, P.Y.4    Li, L.5    Hanse, E.A.6
  • 148
    • 0742288565 scopus 로고    scopus 로고
    • Regeneration beyond the glial scar
    • doi: 10.1038/nrn1326
    • Silver, J., and Miller, J. H. (2004). Regeneration beyond the glial scar. Nat. Rev. Neurosci. 5, 146-156. doi: 10.1038/nrn1326
    • (2004) Nat. Rev. Neurosci. , vol.5 , pp. 146-156
    • Silver, J.1    Miller, J.H.2
  • 149
    • 84899089800 scopus 로고    scopus 로고
    • MicroRNAs in cardiovascular regenerative medicine: Directing tissue repair and cellular differentiation
    • Sluijter, J. P. G. (2013). MicroRNAs in cardiovascular regenerative medicine: directing tissue repair and cellular differentiation. ISRN Vasc. Med. 2013, 16.
    • (2013) ISRN Vasc. Med. , vol.2013 , pp. 16
    • Sluijter, J.P.G.1
  • 150
    • 18444415448 scopus 로고    scopus 로고
    • Regulation of miRNA expression during neural cell specification
    • doi: 10.1111/j.1460-9568.2005.03978.x
    • Smirnova, L., Grafe, A., Seiler, A., Schumacher, S., Nitsch, R., and Wulczyn, F. G. (2005). Regulation of miRNA expression during neural cell specification. Eur. J. Neurosci. 21, 1469-1477. doi: 10.1111/j.1460-9568.2005.03978.x
    • (2005) Eur. J. Neurosci. , vol.21 , pp. 1469-1477
    • Smirnova, L.1    Grafe, A.2    Seiler, A.3    Schumacher, S.4    Nitsch, R.5    Wulczyn, F.G.6
  • 151
    • 77956192481 scopus 로고    scopus 로고
    • Large-scale expression analysis reveals distinct microRNA profiles at different stages of human neurodevelopment
    • doi: 10.1371/journal.pone.0011109
    • Smith, B., Treadwell, J., Zhang, D., Ly, D., McKinnell, I., Walker, P. R., et al. (2010). Large-scale expression analysis reveals distinct microRNA profiles at different stages of human neurodevelopment. PLoS ONE 5:e11109. doi: 10.1371/journal.pone.0011109
    • (2010) PLoS ONE , vol.5
    • Smith, B.1    Treadwell, J.2    Zhang, D.3    Ly, D.4    McKinnell, I.5    Walker, P.R.6
  • 152
    • 25144440471 scopus 로고    scopus 로고
    • Reactive astrocytes in neural repair and protection
    • doi: 10.1177/1073858405278321
    • Sofroniew, M. V. (2005). Reactive astrocytes in neural repair and protection. Neuroscientist 11, 400-407. doi: 10.1177/1073858405278321
    • (2005) Neuroscientist , vol.11 , pp. 400-407
    • Sofroniew, M.V.1
  • 153
    • 70449678738 scopus 로고    scopus 로고
    • Molecular dissection of reactive astrogliosis and glial scar formation
    • doi: 10.1016/j.tins.2009.08.002
    • Sofroniew, M. V. (2009). Molecular dissection of reactive astrogliosis and glial scar formation. Trends Neurosci. 32, 638-647. doi: 10.1016/j.tins.2009.08.002
    • (2009) Trends Neurosci. , vol.32 , pp. 638-647
    • Sofroniew, M.V.1
  • 154
    • 0034747112 scopus 로고    scopus 로고
    • GeneChip analysis after acute spinal cord injury in rat
    • doi: 10.1046/j.1471-4159.2001.00626.x
    • Song, G., Cechvala, C., Resnick, D. K., Dempsey, R. J., and Rao, V. L. (2001). GeneChip analysis after acute spinal cord injury in rat. J. Neurochem. 79, 804-815. doi: 10.1046/j.1471-4159.2001.00626.x
    • (2001) J. Neurochem. , vol.79 , pp. 804-815
    • Song, G.1    Cechvala, C.2    Resnick, D.K.3    Dempsey, R.J.4    Rao, V.L.5
  • 155
    • 71449107946 scopus 로고    scopus 로고
    • MicroRNAs in inflammation
    • doi: 10.3109/08830180903208303
    • Sonkoly, E., and Pivarcsi, A. (2009). microRNAs in inflammation. Int. Rev. Immunol. 28, 535-561. doi: 10.3109/08830180903208303
    • (2009) Int. Rev. Immunol. , vol.28 , pp. 535-561
    • Sonkoly, E.1    Pivarcsi, A.2
  • 156
    • 39749110083 scopus 로고    scopus 로고
    • Small non-coding RNAs in animal development
    • doi: 10.1038/nrm2347
    • Stefani, G., and Slack, F. J. (2008). Small non-coding RNAs in animal development. Nat. Rev. Mol. Cell Biol. 9, 219-230. doi: 10.1038/nrm2347
    • (2008) Nat. Rev. Mol. Cell Biol. , vol.9 , pp. 219-230
    • Stefani, G.1    Slack, F.J.2
  • 157
    • 79957972917 scopus 로고    scopus 로고
    • MicroRNA dysregulation following spinal cord contusion: Implications for neural plasticity and repair
    • doi: 10.1016/j.neuroscience.2011.03.063
    • Strickland, E. R., Hook, M. A., Balaraman, S., Huie, J. R., Grau, J. W., and Miranda, R. C. (2011). MicroRNA dysregulation following spinal cord contusion: implications for neural plasticity and repair. Neuroscience 186, 146-160. doi: 10.1016/j.neuroscience.2011.03.063
    • (2011) Neuroscience , vol.186 , pp. 146-160
    • Strickland, E.R.1    Hook, M.A.2    Balaraman, S.3    Huie, J.R.4    Grau, J.W.5    Miranda, R.C.6
  • 158
    • 0036883891 scopus 로고    scopus 로고
    • Overexpression of SOD1 protects vulnerable motor neurons after spinal cord injury by attenuating mitochondrial cytochrome c release
    • Sugawara, T., Lewen, A., Gasche, Y., Yu, F., and Chan, P. H. (2002). Overexpression of SOD1 protects vulnerable motor neurons after spinal cord injury by attenuating mitochondrial cytochrome c release. FASEB J. 16, 1997-1999.
    • (2002) FASEB J. , vol.16 , pp. 1997-1999
    • Sugawara, T.1    Lewen, A.2    Gasche, Y.3    Yu, F.4    Chan, P.H.5
  • 159
    • 33747608638 scopus 로고    scopus 로고
    • NF-κB-dependent induction of microRNA miR-146, an inhibitor targeted to signaling proteins of innate immune responses
    • doi: 10.1073/pnas.0605298103
    • Taganov, K. D., Boldin, M. P., Chang, K. J., and Baltimore, D. (2006). NF-κB-dependent induction of microRNA miR-146, an inhibitor targeted to signaling proteins of innate immune responses. Proc. Natl. Acad. Sci. U.S.A. 103, 12481-12486. doi: 10.1073/pnas.0605298103
    • (2006) Proc. Natl. Acad. Sci. U.S.A. , vol.103 , pp. 12481-12486
    • Taganov, K.D.1    Boldin, M.P.2    Chang, K.J.3    Baltimore, D.4
  • 160
    • 79958020894 scopus 로고    scopus 로고
    • Deletion of astroglial dicer causes non-cell-autonomous neuronal dysfunction and degeneration
    • doi: 10.1523/JNEUROSCI.0567-11.2011
    • Tao, J., Wu, H., Lin, Q., Wei, W., Lu, X. H., Cantle, J. P., et al. (2011). Deletion of astroglial dicer causes non-cell-autonomous neuronal dysfunction and degeneration. J. Neurosci. 31, 8306-8319. doi: 10.1523/JNEUROSCI.0567-11.2011
    • (2011) J. Neurosci. , vol.31 , pp. 8306-8319
    • Tao, J.1    Wu, H.2    Lin, Q.3    Wei, W.4    Lu, X.H.5    Cantle, J.P.6
  • 161
    • 0030845563 scopus 로고    scopus 로고
    • Role of neutrophils in spinal cord injury in the rat
    • doi: 10.1016/S0306-4522(97)00011-0
    • Taoka, Y., Okajima, K., Uchiba, M., Murakami, K., Kushimoto, S., Johno, M., et al. (1997). Role of neutrophils in spinal cord injury in the rat. Neuroscience 79, 1177-1182. doi: 10.1016/S0306-4522(97)00011-0
    • (1997) Neuroscience , vol.79 , pp. 1177-1182
    • Taoka, Y.1    Okajima, K.2    Uchiba, M.3    Murakami, K.4    Kushimoto, S.5    Johno, M.6
  • 162
    • 38049030287 scopus 로고    scopus 로고
    • Modulation of miR-155 and miR-125b levels following lipopolysaccharide/TNF-alpha stimulation and their possible roles in regulating the response to endotoxin shock
    • Tili, E., Michaille, J. J., Cimino, A., Costinean, S., Dumitru, C. D., Adair, B., et al. (2007). Modulation of miR-155 and miR-125b levels following lipopolysaccharide/TNF-alpha stimulation and their possible roles in regulating the response to endotoxin shock. J. Immunol. 179, 5082-5089.
    • (2007) J. Immunol. , vol.179 , pp. 5082-5089
    • Tili, E.1    Michaille, J.J.2    Cimino, A.3    Costinean, S.4    Dumitru, C.D.5    Adair, B.6
  • 163
    • 84859318003 scopus 로고    scopus 로고
    • Regulation of microRNA biogenesis and function
    • doi: 10.1160/TH11-12-0836
    • Treiber, T., Treiber, N., and Meister, G. (2012). Regulation of microRNA biogenesis and function. Thromb. Haemost. 107, 605-610. doi: 10.1160/TH11-12-0836
    • (2012) Thromb. Haemost. , vol.107 , pp. 605-610
    • Treiber, T.1    Treiber, N.2    Meister, G.3
  • 164
    • 77950348609 scopus 로고    scopus 로고
    • Genome-wide dissection of microRNA functions and cotargeting networks using gene set signatures
    • doi: 10.1016/j.molcel.2010.03.007
    • Tsang, J. S., Ebert, M. S., and van Oudenaarden, A. (2010). Genome-wide dissection of microRNA functions and cotargeting networks using gene set signatures. Mol. Cell 38, 140-153. doi: 10.1016/j.molcel.2010.03.007
    • (2010) Mol. Cell , vol.38 , pp. 140-153
    • Tsang, J.S.1    Ebert, M.S.2    van Oudenaarden, A.3
  • 165
    • 0037102724 scopus 로고    scopus 로고
    • Treatment of spinal cord impact injury in the rat with transforming growth factor-beta
    • doi: 10.1016/S0022-510X(02)00113-2
    • Tyor, W. R., Avgeropoulos, N., Ohlandt, G., and Hogan, E. L. (2002). Treatment of spinal cord impact injury in the rat with transforming growth factor-beta. J. Neurol. Sci. 200, 33-41. doi: 10.1016/S0022-510X(02)00113-2
    • (2002) J. Neurol. Sci. , vol.200 , pp. 33-41
    • Tyor, W.R.1    Avgeropoulos, N.2    Ohlandt, G.3    Hogan, E.L.4
  • 166
    • 4744366168 scopus 로고    scopus 로고
    • Patterns of gene expression reveal a temporally orchestrated wound healing response in the injured spinal cord
    • doi: 10.1523/JNEUROSCI.3316-04.2004
    • Velardo, M. J., Burger, C., Williams, P. R., Baker, H. V., Lopez, M. C., Mareci, T. H., et al. (2004). Patterns of gene expression reveal a temporally orchestrated wound healing response in the injured spinal cord. J. Neurosci. 24, 8562-8576. doi: 10.1523/JNEUROSCI.3316-04.2004
    • (2004) J. Neurosci. , vol.24 , pp. 8562-8576
    • Velardo, M.J.1    Burger, C.2    Williams, P.R.3    Baker, H.V.4    Lopez, M.C.5    Mareci, T.H.6
  • 167
    • 34147157651 scopus 로고    scopus 로고
    • The microRNA miR-124 antagonizes the anti-neural REST/SCP1 pathway during embryonic CNS development
    • doi: 10.1101/gad.1519107
    • Visvanathan, J., Lee, S., Lee, B., Lee, J. W., and Lee, S. K. (2007). The microRNA miR-124 antagonizes the anti-neural REST/SCP1 pathway during embryonic CNS development. Genes Dev. 21, 744-749. doi: 10.1101/gad.1519107
    • (2007) Genes Dev. , vol.21 , pp. 744-749
    • Visvanathan, J.1    Lee, S.2    Lee, B.3    Lee, J.W.4    Lee, S.K.5
  • 168
    • 80055072052 scopus 로고    scopus 로고
    • NF-κB P50/P65 hetero-dimer mediates differential regulation of CD166/ALCAM expression via interaction with micoRNA-9 after serum deprivation, providing evidence for a novel negative auto-regulatory loop
    • doi: 10.1093/nar/gkr302
    • Wang, J., Gu, Z., Ni, P., Qiao, Y., Chen, C., Liu, X., et al. (2011). NF-κB P50/P65 hetero-dimer mediates differential regulation of CD166/ALCAM expression via interaction with micoRNA-9 after serum deprivation, providing evidence for a novel negative auto-regulatory loop. Nucleic Acids Res. 39, 6440-6455. doi: 10.1093/nar/gkr302
    • (2011) Nucleic Acids Res. , vol.39 , pp. 6440-6455
    • Wang, J.1    Gu, Z.2    Ni, P.3    Qiao, Y.4    Chen, C.5    Liu, X.6
  • 169
    • 33748351161 scopus 로고    scopus 로고
    • Computational expression deconvolution in a complex mammalian organ
    • doi: 10.1186/1471-2105-7-328
    • Wang, M., Master, S. R., and Chodosh, L. A. (2006). Computational expression deconvolution in a complex mammalian organ. BMC Bioinformatics 7:328. doi: 10.1186/1471-2105-7-328
    • (2006) BMC Bioinformatics , vol.7 , pp. 328
    • Wang, M.1    Master, S.R.2    Chodosh, L.A.3
  • 170
    • 78650179147 scopus 로고    scopus 로고
    • MicroRNA: A matter of life or death
    • doi: 10.4331/wjbc.v1.i4.41
    • Wang, Z. (2010). MicroRNA: a matter of life or death. World J. Biol. Chem. 1, 41-54. doi: 10.4331/wjbc.v1.i4.41
    • (2010) World J. Biol. Chem. , vol.1 , pp. 41-54
    • Wang, Z.1
  • 172
    • 66049153398 scopus 로고    scopus 로고
    • Evolution under canalization and the dual roles of microRNAs: A hypothesis
    • doi: 10.1101/gr.084640.108
    • Wu, C. I., Shen, Y., and Tang, T. (2009). Evolution under canalization and the dual roles of microRNAs: a hypothesis. Genome Res. 19, 734-743. doi: 10.1101/gr.084640.108
    • (2009) Genome Res. , vol.19 , pp. 734-743
    • Wu, C.I.1    Shen, Y.2    Tang, T.3
  • 173
    • 38349016948 scopus 로고    scopus 로고
    • MiRNA profiling of naive, effector and memory CD8 T cells
    • doi: 10.1371/journal.pone.0001020
    • Wu, H., Neilson, J. R., Kumar, P., Manocha, M., Shankar, P., Sharp, P. A., et al. (2007). miRNA profiling of naive, effector and memory CD8 T cells. PLoS ONE 2:e1020. doi: 10.1371/journal.pone.0001020
    • (2007) PLoS ONE , vol.2
    • Wu, H.1    Neilson, J.R.2    Kumar, P.3    Manocha, M.4    Shankar, P.5    Sharp, P.A.6
  • 174
    • 18844367661 scopus 로고    scopus 로고
    • Real-time quantitative PCR analysis of temporal-spatial alterations in gene expression after spinal cord contusion
    • doi: 10.1111/j.1471-4159.2005.03078.x
    • Wu, X., Yoo, S., and Wrathall, J. R. (2005). Real-time quantitative PCR analysis of temporal-spatial alterations in gene expression after spinal cord contusion. J. Neurochem. 93, 943-952. doi: 10.1111/j.1471-4159.2005.03078.x
    • (2005) J. Neurochem. , vol.93 , pp. 943-952
    • Wu, X.1    Yoo, S.2    Wrathall, J.R.3
  • 175
    • 73949095800 scopus 로고    scopus 로고
    • Bone morphogenetic proteins mediate cellular response and, together with Noggin, regulate astrocyte differentiation after spinal cord injury
    • doi: 10.1016/j.expneurol.2009.12.003
    • Xiao, Q., Du, Y., Wu, W., and Yip, H. K. (2010). Bone morphogenetic proteins mediate cellular response and, together with Noggin, regulate astrocyte differentiation after spinal cord injury. Exp. Neurol. 221, 353-366. doi: 10.1016/j.expneurol.2009.12.003
    • (2010) Exp. Neurol. , vol.221 , pp. 353-366
    • Xiao, Q.1    Du, Y.2    Wu, W.3    Yip, H.K.4
  • 176
    • 17844406364 scopus 로고    scopus 로고
    • Severity-dependent expression of pro-inflammatory cytokines in traumatic spinal cord injury in the rat
    • doi: 10.1016/j.jocn.2004.06.011
    • Yang, L., Jones, N. R., Blumbergs, P. C., Van Den Heuvel, C., Moore, E. J., Manavis, J., et al. (2005). Severity-dependent expression of pro-inflammatory cytokines in traumatic spinal cord injury in the rat. J. Clin. Neurosci. 12, 276-284. doi: 10.1016/j.jocn.2004.06.011
    • (2005) J. Clin. Neurosci. , vol.12 , pp. 276-284
    • Yang, L.1    Jones, N.R.2    Blumbergs, P.C.3    Van Den Heuvel, C.4    Moore, E.J.5    Manavis, J.6
  • 177
    • 77950679650 scopus 로고    scopus 로고
    • Have tumor suppressor PDCD4 and its counteragent oncogenic miR-21 gone rogue?
    • doi: 10.1124/mi.10.2.5
    • Young, M. R., Santhanam, A. N., Yoshikawa, N., and Colburn, N. H. (2010). Have tumor suppressor PDCD4 and its counteragent oncogenic miR-21 gone rogue? Mol. Interv. 10, 76-79. doi: 10.1124/mi.10.2.5
    • (2010) Mol. Interv. , vol.10 , pp. 76-79
    • Young, M.R.1    Santhanam, A.N.2    Yoshikawa, N.3    Colburn, N.H.4
  • 178
    • 48849103603 scopus 로고    scopus 로고
    • MicroRNA miR-124 regulates neurite outgrowth during neuronal differentiation
    • doi: 10.1016/j.yexcr.2008.06.002
    • Yu, J. Y., Chung, K. H., Deo, M., Thompson, R. C., and Turner, D. L. (2008). MicroRNA miR-124 regulates neurite outgrowth during neuronal differentiation. Exp. Cell Res. 314, 2618-2633. doi: 10.1016/j.yexcr.2008.06.002
    • (2008) Exp. Cell Res. , vol.314 , pp. 2618-2633
    • Yu, J.Y.1    Chung, K.H.2    Deo, M.3    Thompson, R.C.4    Turner, D.L.5
  • 179
    • 79955534061 scopus 로고    scopus 로고
    • MicroRNA miR-133b is essential for functional recovery after spinal cord injury in adult zebrafish
    • doi: 10.1111/j.1460-9568.2011.07643.x
    • Yu, Y. M., Gibbs, K. M., Davila, J., Campbell, N., Sung, S., Todorova, T. I., et al. (2011). MicroRNA miR-133b is essential for functional recovery after spinal cord injury in adult zebrafish. Eur. J. Neurosci. 33, 1587-1597. doi: 10.1111/j.1460-9568.2011.07643.x
    • (2011) Eur. J. Neurosci. , vol.33 , pp. 1587-1597
    • Yu, Y.M.1    Gibbs, K.M.2    Davila, J.3    Campbell, N.4    Sung, S.5    Todorova, T.I.6
  • 180
    • 84870985082 scopus 로고    scopus 로고
    • MicroRNA dysregulation in the spinal cord following traumatic injury
    • doi: 10.1371/journal.pone.0034534
    • Yunta, M., Nieto-Diaz, M., Esteban, F. J., Caballero-Lopez, M., Navarro-Ruiz, R., Reigada, D., et al. (2012). MicroRNA dysregulation in the spinal cord following traumatic injury. PLoS ONE 7:e34534. doi: 10.1371/journal.pone.0034534
    • (2012) PLoS ONE , vol.7
    • Yunta, M.1    Nieto-Diaz, M.2    Esteban, F.J.3    Caballero-Lopez, M.4    Navarro-Ruiz, R.5    Reigada, D.6
  • 181
    • 84860322835 scopus 로고    scopus 로고
    • Genomic analysis of reactive astrogliosis
    • doi: 10.1523/JNEUROSCI.6221-11.2012
    • Zamanian, J. L., Xu, L., Foo, L. C., Nouri, N., Zhou, L., Giffard, R. G., et al. (2012). Genomic analysis of reactive astrogliosis. J. Neurosci. 32, 6391-6410. doi: 10.1523/JNEUROSCI.6221-11.2012
    • (2012) J. Neurosci. , vol.32 , pp. 6391-6410
    • Zamanian, J.L.1    Xu, L.2    Foo, L.C.3    Nouri, N.4    Zhou, L.5    Giffard, R.G.6
  • 182
    • 84867278201 scopus 로고    scopus 로고
    • Analytical challenges and technical limitations in assessing circulating miRNAs
    • doi: 10.1160/TH12-02-0097
    • Zampetaki, A., and Mayr, M. (2012). Analytical challenges and technical limitations in assessing circulating miRNAs. Thromb. Haemost. 108, 592-598. doi: 10.1160/TH12-02-0097
    • (2012) Thromb. Haemost. , vol.108 , pp. 592-598
    • Zampetaki, A.1    Mayr, M.2
  • 183
    • 4444317633 scopus 로고    scopus 로고
    • Differential gene expression after complete spinal cord transection in adult rats: An analysis focused on a subchronic post-injury stage
    • doi: 10.1016/j.neuroscience.2004.07.008
    • Zhang, K. H., Xiao, H. S., Lu, P. H., Shi, J., Li, G. D., Wang, Y. T., et al. (2004). Differential gene expression after complete spinal cord transection in adult rats: an analysis focused on a subchronic post-injury stage. Neuroscience 128, 375-388. doi: 10.1016/j.neuroscience.2004.07.008
    • (2004) Neuroscience , vol.128 , pp. 375-388
    • Zhang, K.H.1    Xiao, H.S.2    Lu, P.H.3    Shi, J.4    Li, G.D.5    Wang, Y.T.6
  • 184
    • 84860390065 scopus 로고    scopus 로고
    • Altered expression levels of miRNAs in serum as sensitive biomarkers for early diagnosis of traumatic injury
    • doi: 10.1002/jcb.23168
    • Zhang, Y., Liao, Y., Wang, D., He, Y., Cao, D., Zhang, F., et al. (2011). Altered expression levels of miRNAs in serum as sensitive biomarkers for early diagnosis of traumatic injury. J. Cell. Biochem. 112, 2435-2442. doi: 10.1002/jcb.23168
    • (2011) J. Cell. Biochem. , vol.112 , pp. 2435-2442
    • Zhang, Y.1    Liao, Y.2    Wang, D.3    He, Y.4    Cao, D.5    Zhang, F.6
  • 185
    • 76649088031 scopus 로고    scopus 로고
    • MicroRNA let-7b regulates neural stem cell proliferation and differentiation by targeting nuclear receptor TLX signaling
    • doi: 10.1073/pnas.0908750107
    • Zhao, C., Sun, G., Li, S., Lang, M. F., Yang, S., Li, W., et al. (2010a). MicroRNA let-7b regulates neural stem cell proliferation and differentiation by targeting nuclear receptor TLX signaling. Proc. Natl. Acad. Sci. U.S.A. 107, 1876-1881. doi: 10.1073/pnas.0908750107
    • (2010) Proc. Natl. Acad. Sci. U.S.A. , vol.107 , pp. 1876-1881
    • Zhao, C.1    Sun, G.2    Li, S.3    Lang, M.F.4    Yang, S.5    Li, W.6
  • 186
    • 77649166937 scopus 로고    scopus 로고
    • MicroRNA-mediated control of oligodendrocyte differentiation
    • doi: 10.1016/j.neuron.2010.02.018
    • Zhao, X., He, X., Han, X., Yu, Y., Ye, F., Chen, Y., et al. (2010b). MicroRNA-mediated control of oligodendrocyte differentiation. Neuron 65, 612-626. doi: 10.1016/j.neuron.2010.02.018
    • (2010) Neuron , vol.65 , pp. 612-626
    • Zhao, X.1    He, X.2    Han, X.3    Yu, Y.4    Ye, F.5    Chen, Y.6
  • 187
    • 84858783875 scopus 로고    scopus 로고
    • Extracellular/circulating microRNAs and their potential role in cardiovascular disease
    • Zhu, H., and Fan, G. C. (2011). Extracellular/circulating microRNAs and their potential role in cardiovascular disease. Am. J. Cardiovasc. Dis. 1, 138-149.
    • (2011) Am. J. Cardiovasc. Dis. , vol.1 , pp. 138-149
    • Zhu, H.1    Fan, G.C.2
  • 188
    • 84892825385 scopus 로고    scopus 로고
    • Spatial and temporal expression levels of specific microRNAs in a spinal cord injury mouse model and their relationship to the duration of compression
    • doi: 10.1016/j.spinee.2013.08.015
    • Ziu, M., Fletcher, L., Savage, J. G., Jimenez, D. F., Digicaylioglu, M., and Bartanusz, V. (2013). Spatial and temporal expression levels of specific microRNAs in a spinal cord injury mouse model and their relationship to the duration of compression. Spine J. 14, 353-360. doi: 10.1016/j.spinee.2013.08.015
    • (2013) Spine J. , vol.14 , pp. 353-360
    • Ziu, M.1    Fletcher, L.2    Savage, J.G.3    Jimenez, D.F.4    Digicaylioglu, M.5    Bartanusz, V.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.