Micro RNA-125b (miRNA-125b) function in astrogliosis and glial cell proliferation

Neuroscience Letters

Volumn 476, Issue 1, 2010, Pages 18-22

  Pogue, A I ^a   Cui, J G ^a   Li, Y Y ^a   Zhao, Y ^b   Culicchia, F ^c   Lukiw, W J ^a  

^a LOUISIANA STATE UNIVERSITY HEALTH SCIENCES CENTER   (United States)

^b UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^c LOUISIANA STATE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Alzheimer's disease (AD); Astrogliosis; CDKN2A; Cell cycle; Down's syndrome (DS); GFAP; IL 6; MiRNA 125b; Vimentin

Indexed keywords

BETA ACTIN; CYCLIN DEPENDENT KINASE INHIBITOR 2A; GLIAL FIBRILLARY ACIDIC PROTEIN; MICRORNA; MICRORNA 125B; RECOMBINANT INTERLEUKIN 6; UNCLASSIFIED DRUG; VIMENTIN;

ALZHEIMER DISEASE; ARTICLE; ASTROCYTE; ASTROCYTOSIS; CELL PROLIFERATION; CONTROLLED STUDY; DOWN SYNDROME; GENE EXPRESSION; GENE FUNCTION; GLIA CELL; HUMAN; HUMAN CELL; HUMAN TISSUE; IN VITRO STUDY; NEOCORTEX; PRIORITY JOURNAL; UPREGULATION;

ACTINS; ASTROCYTES; CELL PROLIFERATION; CELLS, CULTURED; CYCLIN-DEPENDENT KINASE INHIBITOR P16; GLIAL FIBRILLARY ACIDIC PROTEIN; HUMANS; INTERLEUKIN-6; MICRORNAS; UP-REGULATION; VIMENTIN;

EID: 77952745811     PISSN: 03043940     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neulet.2010.03.054     Document Type: Article

References (25)

1. Brahmachari S., Fung Y.K., Pahan K. Induction of glial fibrillary acidic protein expression in astrocytes by nitric oxide. J. Neurosci. 2006, 26:4930-4939.
2. Buffo A., Rite I., Tripathi P., Lepier A., Colak D., Horn A.P., Mori T., Götz M. Origin and progeny of reactive gliosis. Proc. Natl. Acad. Sci. U.S.A. 2008, 105:3581-3586.
3. Burmistrova O.A., Goltsov A.Y., Abramova L.I., Kaleda V.G., Orlova V.A., Rogaev E.I. MicroRNA in schizophrenia: genetic and expression analysis of miR-130b (22q11). Biochemistry (Mosc.) 2007, 72:578-582.
4. Ciafrè S.A., Galardi S., Mangiola A., Ferracin M., Liu C.G., Sabatino G., Negrini M., Maira G., Croce C.M., Farace M.G. Extensive modulation of a set of miRNAs in glioblastoma. Biochem. Biophys. Res. Commun. 2005, 334:1351-1358.
5. Dolev I., Michaelson D.M. The nucleation, growth and reversibility of amyloid-beta deposition in vivo. J. Alzheimers Dis. 2006, 10:291-301.
6. Eng L.F., Ghirnikar R.S. GFAP Astrogl. Brain Pathol. 2008, 4:229-237.
7. Hill J.M., Zhao Y., Clement C., Neumann D.M., Lukiw W.J. HSV-1 infection of human brain cells induces miRNA-146a and Alzheimer-type inflammatory signaling. Neuroreport 2009, 20:1500-1505.
8. Kuhn D.E., Nuovo G.J., Martin M.M., Malana G.E., Pleister A.P., Jiang J., Schmittgen T.D., Terry A.V., Gardiner K., Head E., Feldman D.S., Elton T.S. Human chromosome 21-derived miRNAs are over-expressed in Down Syndrome brains and hearts. Biochem. Biophys. Res. Commun. 2008, 370:473-477.
9. Le M.T., Xie H., Zhou B., Chia P.H., Rizk P., Um M., Udolph G., Yang H., Lim B., Lodish H.F. MicroRNA-125b promotes differentiation in human cells. Mol. Cell. Biol. 2009, 29:5290-5305.
10. Lee Y.S., Kim H.K., Chung S., Kim K.S., Dutta A. Depletion of human micro-RNA-125b reveals that it is critical for the proliferation of differentiated cells but not for the down-regulation of putative targets during differentiation. J. Biol. Chem. 2005, 280:16635-16641.
11. Lukiw W.J. Micro-RNA speciation in fetal, adult and AD hippocampus. Neuroreport 2007, 18:297-300.
12. Lukiw W.J., Pogue A.I. Induction of specific micro RNA (miRNA) species by ROS-generating metal sulfates in primary human brain cells. J. Inorg. Biochem. 2007, 101:1265-1269.
13. Lukiw W.J., Handley P., Wong L., McLachlan D.R. BC200 RNA in normal human neocortex, non-Alzheimer dementia, and AD. Neurochem. Res. 1992, 17:591-597.
14. Lukiw W.J., Zhao Y., Cui J.G. An NF-κB-sensitive miRNA-146a-mediated inflammatory circuit in AD and stressed human brain cells. J. Biol. Chem. 2008, 283:31315-31322.
15. McTigueM P.M., Peterson R.J., Kahn J.D. Sequence-dependent thermodynamic parameters for locked nucleic acid duplex formation. Biochemistry 2004, 43:5388-5405.
16. Nelson P.T., Baldwin D.A., Kloosterman W.P., Kauppinen S., Plasterk R.H., Mourelatos Z. RAKE and LNA-ISH reveal microRNA expression and localization in archival human brain. RNA 2006, 12:187-191.
17. Pogue A.I., Li Y.Y., Cui J.G., Zhao Y., Kruck T.P., Percy M.E., Tarr M.A., Lukiw W.J. Characterization of an NF-κB-regulated miRNA-146a in metal-sulfate-stressed human brain cells. J. Inorg. Biochem. 2009, 11:156-164.
18. Rieske P., Azizi S.A., Augelli B., Gaughan J., Krynska B. A population of human brain parenchymal cells express markers of glial, neuronal and early neural cells and differentiate into cells of neuronal and glial lineages. Eur. J. Neurosci. 2007, 25:31-37.
19. Rodríguez J.J., Olabarria M., Chvatal A., Verkhratsky A. Astroglia in dementia and AD. Cell Death Differ. 2009, 16:378-385.
20. Sethi P., Lukiw W.J. Micro-RNA abundance and stability in human brain: specific alterations in AD temporal lobe neocortex. Neurosci. Lett. 2009, 459:100-104.
21. Smirnova L., Gräfe A., Seiler A., Schumacher S., Nitsch R., Wulczyn: F.G. Regulation of miRNA expression during neural cell specification. Eur. J. Neurosci. 2005, 21:1469-1477.
22. Tilgner J., Volk B., Kaltschmidt C. Continuous IL-6 application in vivo via macroencapsulation of interleukin-6-expressing COS-7 cells induces massive gliosis. Glia 2001, 35:234-245.
23. Xia H.F., He T.Z., Liu C.M., Cui Y., Song P.P., Jin X.H., Ma X. MicroRNA-125b expression affects the proliferation and apoptosis of human glioma cells by targeting Bmf. Cell. Physiol. Biochem. 2009, 23:347-358.
24. Zhang Y., Gao J.S., Tang X., Tucker L.D., Quesenberry P., Rigoutsos I., Ramratnam B. MicroRNA 125 and its regulation of the p53 tumor suppressor gene. FEBS Lett. 2009, 583:3725-3730.
25. Züchner S., Gilbert J.R., Martin E.R., Leon-Guerrero C.R., Xu P.T., Browning C., Bronson P.G., Whitehead P., Schmechel D.E., Haines J.L., Pericak-Vance M.A. Linkage and association study of late-onset Alzheimer disease families linked to 9p21.3. Ann. Hum. Genet. 2008, 72:725-731.