Genomewide microRNA down-regulation as a negative feedback mechanism in the early phases of liver regeneration

Hepatology

Volumn 54, Issue 2, 2011, Pages 609-619

  Shu, Jingmin ^a   Kren, Betsy T ^a   Xia, Zhilian ^a   Wong, Phillip Y P ^a   Li, Lihua ^a   Hanse, Eric A ^b   Min, Michael X ^a   Li, Bingshan ^c   Albrecht, Jeffrey H ^b   Zeng, Yan ^a   Subramanian, Subbaya ^a   Steer, Clifford J ^a  

^a UNIVERSITY OF MINNESOTA MEDICAL SCHOOL   (United States)

^b MINNEAPOLIS MEDICAL RESEARCH FOUNDATION   (United States)

^c UNIVERSITY OF MICHIGAN   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MICRORNA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; BIOGENESIS; CELL CYCLE; CELL PROLIFERATION; CONTROLLED STUDY; DOWN REGULATION; FEEDBACK SYSTEM; GENE EXPRESSION; GENE OVEREXPRESSION; GENOME ANALYSIS; HEPATOMA CELL; HUMAN; HUMAN CELL; LIVER CELL; LIVER REGENERATION; MALE; MICROARRAY ANALYSIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; REVIEW; UPREGULATION;

ANIMALS; CELLS, CULTURED; DOWN-REGULATION; FEEDBACK, PHYSIOLOGICAL; GENOME-WIDE ASSOCIATION STUDY; HUMANS; LIVER REGENERATION; MALE; MICRORNAS; RATS; RATS, SPRAGUE-DAWLEY;

EID: 79960743857     PISSN: 02709139     EISSN: 15273350     Source Type: Journal    
DOI: 10.1002/hep.24421     Document Type: Review

References (31)

1. Steer CJ. Liver regeneration. FASEB J 1995; 9: 1396-1400.
2. 3. Cancer Res 1962; 22: 842-849.
3. Fausto N. Liver regeneration. J Hepatol 2000; 32: 19-31.
4. Taub R. Liver regeneration: from myth to mechanism. Nat Rev Mol Cell Biol 2004; 5: 836-847.
5. Michalopoulos GK. Liver regeneration. J Cell Physiol 2007; 213: 286-300.
6. Cai X, Hagedorn CH, Cullen BR. Human microRNAs are processed from capped, polyadenylated transcripts that can also function as mRNAs. RNA 2004; 10: 1957-1966.
7. Gregory RI, Yan KP, Amuthan G, Chendrimada T, Doratotaj B, Cooch N, Shiekhattar R. The microprocessor complex mediates the genesis of microRNAs. Nature 2004; 432: 235-240.
8. Bartel DP. MicroRNAs: target recognition and regulatory functions. Cell 2009; 136: 215-233.
9. Lu J, Getz G, Miska EA, Alvarez-Saavedra E, Lamb J, Peck D, et al. MicroRNA expression profiles classify human cancers. Nature 2005; 435: 834-838.
10. Kanellopoulou C, Muljo SA, Kung AL, Ganesan S, Drapkin R, Jenuwein T, et al. Dicer-deficient mouse embryonic stem cells are defective in differentiation and centromeric silencing. Genes Dev 2005; 19: 489-501.
11. Sood P, Krek A, Zavolan M, Macino G, Rajewsky N. Cell-type-specific signatures of microRNAs on target mRNA expression. Proc Natl Acad Sci U S A 2006; 103: 2746-2751.
12. Krutzfeldt J, Rajewsky N, Braich R, Rajeev KG, Tuschl T, Manoharan M, Stoffel M. Silencing of microRNAs in vivo with "antagomirs". Nature 2005; 438: 685-689.
13. Esau C, Davis S, Murray SF, Yu XX, Pandey SK, Pear M, et al. miR-122 regulation of lipid metabolism revealed by in vivo antisense targeting. Cell Metab 2006; 3: 87-98.
14. Chang J, Nicolas E, Marks D, Sander C, Lerro A, Buendia MA, et al. miR-122, a mammalian liver-specific microRNA, is processed from hcr mRNA and may downregulate the high affinity cationic amino acid transporter CAT-1. RNA Biol 2004; 1: 106-113.
15. Song KH, Li T, Owsley E, Chiang JY. A putative role of microRNA in regulation of cholesterol 7α-hydroxylase expression in human hepatocytes. J Lipid Res 2010; 51: 2223-2233.
16. Kutay H, Bai S, Datta J, Motiwala T, Pogribny I, Frankel W, et al. Downregulation of miR-122 in the rodent and human hepatocellular carcinomas. J Cell Biochem 2006; 99: 671-678.
17. Sekine S, Ogawa R, Ito R, Hiraoka N, McManus MT, Kanai Y, et al. Disruption of Dicer1 induces dysregulated fetal gene expression and promotes hepatocarcinogenesis. Gastroenterology 2009; 136: 2304-2315.
18. Marquez RT, Wendlandt E, Galle CS, Keck K, McCaffrey AP. MicroRNA-21 is upregulated during the proliferative phase of liver regeneration, targets Pellino-1, and inhibits NF-κB signaling. Am J Physiol Gastrointest Liver Physiol 2010; 298: G535-G541.
19. Kalscheuer S, Zhang X, Zeng Y, Upadhyaya P. Differential expression of microRNAs in early-stage neoplastic transformation in the lungs of F344 rats chronically treated with the tobacco carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone. Carcinogenesis 2008; 29: 2394-2399.
20. Kren BT, Wong PY, Shiota A, Zhang X, Zeng Y, Steer CJ. Polysome trafficking of transcripts and microRNAs in regenerating liver after partial hepatectomy. Am J Physiol Gastrointest Liver Physiol 2009; 297: G1181-G1192.
21. Bandyopadhyay P, Kren BT, Ma X, Steer CJ. Enhanced gene transfer into HuH-7 cells and primary rat hepatocytes using targeted liposomes and polyethylenimine. Biotechniques 1998; 25: 282-284, 286-292.
22. Hand NJ, Master ZR, Le Lay J, Friedman JR. Hepatic function is preserved in the absence of mature microRNAs. Hepatology 2009; 49: 618-626.
23. Song G, Sharma AD, Roll GR, Ng R, Lee AY, Blelloch RH, et al. MicroRNAs control hepatocyte proliferation during liver regeneration. Hepatology 2010; 51: 1735-1743.
24. Maes OC, An J, Sarojini H, Wang E. Murine microRNAs implicated in liver functions and aging process. Mech Ageing Dev 2008; 129: 534-541.
25. Kren BT, Steer CJ. Posttranscriptional regulation of gene expression in liver regeneration: role of mRNA stability. FASEB J 1996; 10: 559-573.
26. Kim TH, Mars WM, Stolz DB, Michalopoulos GK. Expression and activation of pro-MMP-2 and pro-MMP-9 during rat liver regeneration. Hepatology 2000; 31: 75-82.
27. Campbell JS, Prichard L, Schaper F, Schmitz J, Stephenson-Famy A, Rosenfeld ME, et al. Expression of suppressors of cytokine signaling during liver regeneration. J Clin Invest 2001; 107: 1285-1292.
28. Greenbaum LE, Cressman DE, Haber BA, Taub R. Coexistence of C/EBP α, β, growth-induced proteins and DNA synthesis in hepatocytes during liver regeneration. Implications for maintenance of the differentiated state during liver growth. J Clin Invest 1995; 96: 1351-1365.
29. Forman JJ, Legesse-Miller A, Coller HA. A search for conserved sequences in coding regions reveals that the let-7 microRNA targets Dicer within its coding sequence. Proc Natl Acad Sci U S A 2008; 105: 14879-14884.
30. Tokumaru S, Suzuki M, Yamada H, Nagino M, Takahashi T. let-7 regulates Dicer expression and constitutes a negative feedback loop. Carcinogenesis 2008; 29: 2073-2077.
31. Volinia S, Calin GA, Liu CG, Ambs S, Cimmino A, Petrocca F, et al. A microRNA expression signature of human solid tumors defines cancer gene targets. Proc Natl Acad Sci U S A 2006; 103: 2257-2261.