-
1
-
-
0026632325
-
Identification of an N-terminal domain of eukaryotic DNA topoisomerase I dispensable for catalytic activity but essential for in vivo function
-
Alsner J, Svejstrup JQ, Kjeldsen E, Sorensen BS, Westergaard O (1992) Identification of an N-terminal domain of eukaryotic DNA topoisomerase I dispensable for catalytic activity but essential for in vivo function. J Biol Chem 267(18): 12408-12411
-
(1992)
J Biol Chem
, vol.267
, Issue.18
, pp. 12408-12411
-
-
Alsner, J.1
Svejstrup, J.Q.2
Kjeldsen, E.3
Sorensen, B.S.4
Westergaard, O.5
-
2
-
-
0036392194
-
The RNA splicing factor ASF/SF2 inhibits human topoisomerase I mediated DNA relaxation
-
Andersen FF, Tange TO, Sinnathamby T, Olesen JR, Andersen KE, Westergaard O, Kjems J, Knudsen BR (2002) The RNA splicing factor ASF/SF2 inhibits human topoisomerase I mediated DNA relaxation. J Mol Biol 322(4): 677-686
-
(2002)
J Mol Biol
, vol.322
, Issue.4
, pp. 677-686
-
-
Andersen, F.F.1
Tange, T.O.2
Sinnathamby, T.3
Olesen, J.R.4
Andersen, K.E.5
Westergaard, O.6
Kjems, J.7
Knudsen, B.R.8
-
3
-
-
0023807621
-
Camptothecin, a specific inhibitor of type I DNA topoisomerase, induces DNA breakage at replication forks
-
Avemann K, Knippers R, Koller T, Sogo JM (1988) Camptothecin, a specific inhibitor of type I DNA topoisomerase, induces DNA breakage at replication forks. Mol Cell Biol 8(8): 3026-3034
-
(1988)
Mol Cell Biol
, vol.8
, Issue.8
, pp. 3026-3034
-
-
Avemann, K.1
Knippers, R.2
Koller, T.3
Sogo, J.M.4
-
4
-
-
0028795337
-
Cell cycle analysis of amount and distribution of nuclear DNA topoisomerase I as determined by fluorescence digital imaging microscopy
-
Baker SD, Wadkins RM, Stewart CF, Beck WT, Danks MK (1995) Cell cycle analysis of amount and distribution of nuclear DNA topoisomerase I as determined by fluorescence digital imaging microscopy. Cytometry 19(2): 134-145
-
(1995)
Cytometry
, vol.19
, Issue.2
, pp. 134-145
-
-
Baker, S.D.1
Wadkins, R.M.2
Stewart, C.F.3
Beck, W.T.4
Danks, M.K.5
-
5
-
-
37049037760
-
Serine phosphorylation-dependent coregulation of topoisomerase I by the p14ARF tumor suppressor
-
Bandyopadhyay K, Lee C, Haghighi A, Baneres JL, Parello J, Gjerset RA (2007) Serine phosphorylation-dependent coregulation of topoisomerase I by the p14ARF tumor suppressor. Biochemistry 46(49): 14325-14334
-
(2007)
Biochemistry
, vol.46
, Issue.49
, pp. 14325-14334
-
-
Bandyopadhyay, K.1
Lee, C.2
Haghighi, A.3
Baneres, J.L.4
Parello, J.5
Gjerset, R.A.6
-
6
-
-
0035850913
-
Molecular interactions between poly(ADP-ribose) polymerase (PARP I) and topoisomerase I (Topo I): Identification of topology of binding
-
Bauer PI, Chen HJ, Kenesi E, Kenessey I, Buki KG, Kirsten E, Hakam A, Hwang JI, Kun E (2001) Molecular interactions between poly(ADP-ribose) polymerase (PARP I) and topoisomerase I (Topo I): identification of topology of binding. FEBS Lett 506(3): 239-242
-
(2001)
FEBS Lett
, vol.506
, Issue.3
, pp. 239-242
-
-
Bauer, P.I.1
Chen, H.J.2
Kenesi, E.3
Kenessey, I.4
Buki, K.G.5
Kirsten, E.6
Hakam, A.7
Hwang, J.I.8
Kun, E.9
-
7
-
-
0021760306
-
Nucleotide sequence preference at rat liver and wheat germ type 1 DNA topoisomerase breakage sites in duplex SV40 DNA
-
Been MD, Burgess RR, Champoux JJ (1984) Nucleotide sequence preference at rat liver and wheat germ type 1 DNA topoisomerase breakage sites in duplex SV40 DNA. Nucleic Acids Res 12(7): 3097-3114
-
(1984)
Nucleic Acids Res
, vol.12
, Issue.7
, pp. 3097-3114
-
-
Been, M.D.1
Burgess, R.R.2
Champoux, J.J.3
-
8
-
-
0019568339
-
DNA breakage and closure by rat liver type 1 topoisomerase: Separation of the half-reactions by using a single-stranded DNA substrate
-
Been MD, Champoux JJ (1981) DNA breakage and closure by rat liver type 1 topoisomerase: separation of the half-reactions by using a single-stranded DNA substrate. Proc Natl Acad Sci USA 78(5): 2883-2887
-
(1981)
Proc Natl Acad Sci USA
, vol.78
, Issue.5
, pp. 2883-2887
-
-
Been, M.D.1
Champoux, J.J.2
-
9
-
-
0030047434
-
Identification of a nucleolin binding site in human topoisomerase I
-
Bharti AK, Olson MO, Kufe DW, Rubin EH (1996) Identification of a nucleolin binding site in human topoisomerase I. Journal Of Biological Chemistry 271(4): P 1993-1997
-
(1996)
Journal Of Biological Chemistry
, vol.271
, Issue.4
, pp. 1993-1997
-
-
Bharti, A.K.1
Olson, M.O.2
Kufe, D.W.3
Rubin, E.H.4
-
10
-
-
0022369729
-
A high affinity topoisomerase I binding sequence is clustered at DNAase I hypersensitive sites in Tetrahymena R-chromatin
-
Bonven BJ, Gocke E, Westergaard O (1985) A high affinity topoisomerase I binding sequence is clustered at DNAase I hypersensitive sites in Tetrahymena R-chromatin. Cell 41(2): 541-551
-
(1985)
Cell
, vol.41
, Issue.2
, pp. 541-551
-
-
Bonven, B.J.1
Gocke, E.2
Westergaard, O.3
-
11
-
-
33846682284
-
NKX3.1 homeodomain protein binds to topoisomerase I and enhances its activity
-
Bowen C, Stuart A, Ju JH, Tuan J, Blonder J, Conrads TP, Veenstra TD, Gelmann EP (2007) NKX3.1 homeodomain protein binds to topoisomerase I and enhances its activity. Cancer Res 67(2): 455-464
-
(2007)
Cancer Res
, vol.67
, Issue.2
, pp. 455-464
-
-
Bowen, C.1
Stuart, A.2
Ju, J.H.3
Tuan, J.4
Blonder, J.5
Conrads, T.P.6
Veenstra, T.D.7
Gelmann, E.P.8
-
12
-
-
0023639882
-
DNA topoisomerase activity is required as a swivel for DNA replication and for ribosomal RNA transcription
-
Brill SJ, DiNardo S, Voelkel-Meiman K, Sternglanz R (1987) DNA topoisomerase activity is required as a swivel for DNA replication and for ribosomal RNA transcription. NCI Monogr 4: 11-15
-
(1987)
NCI Monogr
, vol.4
, pp. 11-15
-
-
Brill, S.J.1
DiNardo, S.2
Voelkel-meiman, K.3
Sternglanz, R.4
-
13
-
-
0022409106
-
Association of crossover points with topoisomerase I cleavage sites: A model for nonhomologous recombination
-
Bullock P, Champoux JJ, Botchan M (1985) Association of crossover points with topoisomerase I cleavage sites: a model for nonhomologous recombination. Science 230(4728): 954-958
-
(1985)
Science
, vol.230
, Issue.4728
, pp. 954-958
-
-
Bullock, P.1
Champoux, J.J.2
Botchan, M.3
-
14
-
-
0024297005
-
Eukaryotic DNA topoisomerase I reaction is topology dependent
-
Camilloni G, Di Martino E, Caserta M, di Mauro E (1988) Eukaryotic DNA topoisomerase I reaction is topology dependent. Nucleic Acids Res 16(14B): 7071-7085
-
(1988)
Nucleic Acids Res
, vol.16
, Issue.14 B
, pp. 7071-7085
-
-
Camilloni, G.1
Di Martino, E.2
Caserta, M.3
di Mauro, E.4
-
15
-
-
0037948842
-
DNA relaxation by human topoisomerase I occurs in the closed clamp conformation of the protein
-
Carey JF, Schultz SJ, Sisson L, Fazzio TG, Champoux JJ (2003) DNA relaxation by human topoisomerase I occurs in the closed clamp conformation of the protein. Proc Natl Acad Sci USA 100(10): 5640-5645
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, Issue.10
, pp. 5640-5645
-
-
Carey, J.F.1
Schultz, S.J.2
Sisson, L.3
Fazzio, T.G.4
Champoux, J.J.5
-
16
-
-
0036690387
-
Hyperphosphorylated C-terminal repeat domain-associating proteins in the nuclear proteome link transcription to DNA/chromatin modification and RNA processing
-
Carty SM, Greenleaf AL (2002) Hyperphosphorylated C-terminal repeat domain-associating proteins in the nuclear proteome link transcription to DNA/chromatin modification and RNA processing. Mol Cell Proteomics 1(8): 598-610
-
(2002)
Mol Cell Proteomics
, vol.1
, Issue.8
, pp. 598-610
-
-
Carty, S.M.1
Greenleaf, A.L.2
-
17
-
-
0025075146
-
Regulation of the function of eukaryotic DNA topoisomerase I: Analysis of the binding step and of the catalytic constants of topoisomerization as a function of DNA topology
-
Caserta M, Amadei A, Camilloni G, Di Mauro E (1990) Regulation of the function of eukaryotic DNA topoisomerase I: analysis of the binding step and of the catalytic constants of topoisomerization as a function of DNA topology. Biochemistry 29(35): 8152-8157
-
(1990)
Biochemistry
, vol.29
, Issue.35
, pp. 8152-8157
-
-
Caserta, M.1
Amadei, A.2
Camilloni, G.3
Di Mauro, E.4
-
18
-
-
0024448449
-
In vitro preferential topoisomerization of bent DNA
-
Caserta M, Amadei A, Di Mauro E, Camilloni G (1989) In vitro preferential topoisomerization of bent DNA. Nucleic Acids Res 17(21): 8463-8474
-
(1989)
Nucleic Acids Res
, vol.17
, Issue.21
, pp. 8463-8474
-
-
Caserta, M.1
Amadei, A.2
Di Martino, E.3
Camilloni, G.4
-
19
-
-
0002827166
-
Evidence for an intermediate with a single-strand break in the reaction catalyzed by the DNA untwisting enzyme
-
Champoux JJ (1976) Evidence for an intermediate with a single-strand break in the reaction catalyzed by the DNA untwisting enzyme. Proc Natl Acad Sci USA 73(10): 3488-3491
-
(1976)
Proc Natl Acad Sci USA
, vol.73
, Issue.10
, pp. 3488-3491
-
-
Champoux, J.J.1
-
20
-
-
0017708066
-
Strand breakage by the DNA untwisting enzyme results in covalent attachment of the enzyme to DNA
-
Champoux JJ (1977) Strand breakage by the DNA untwisting enzyme results in covalent attachment of the enzyme to DNA. Proc Natl Acad Sci USA 74(9): 3800-3804
-
(1977)
Proc Natl Acad Sci USA
, vol.74
, Issue.9
, pp. 3800-3804
-
-
Champoux, J.J.1
-
21
-
-
0026654950
-
Topoisomerase I is preferentially associated with normal SV40 replicative intermediates, but is associated with both replicating and nonreplicating SV40 DNAs which are deficient in histones
-
Champoux JJ (1992) Topoisomerase I is preferentially associated with normal SV40 replicative intermediates, but is associated with both replicating and nonreplicating SV40 DNAs which are deficient in histones. Nucleic Acids Res 20(13): 3347-3352
-
(1992)
Nucleic Acids Res
, vol.20
, Issue.13
, pp. 3347-3352
-
-
Champoux, J.J.1
-
22
-
-
0034923502
-
DNA topoisomerases: Structure, function, and mechanism
-
Champoux JJ (2001) DNA topoisomerases: structure, function, and mechanism. Annu Rev Biochem 70: 369-413
-
(2001)
Annu Rev Biochem
, vol.70
, pp. 369-413
-
-
Champoux, J.J.1
-
23
-
-
0021646231
-
DNA structural features that lead to strand breakage by eukaryotic type-I topoisomerase
-
Champoux JJ, McCoubrey WK, Jr., Been MD (1984) DNA structural features that lead to strand breakage by eukaryotic type-I topoisomerase. Cold Spring Harb Symp Quant Biol 49: 435-442
-
(1984)
Cold Spring Harb Symp Quant Biol
, vol.49
, pp. 435-442
-
-
Champoux, J.J.1
McCoubrey, W.K.2
Been, M.D.3
-
24
-
-
2542490127
-
Distinct effects of topoisomerase I and RNA polymerase I inhibitors suggest a dual mechanism of nucleolar/nucleoplasmic partitioning of topoisomerase I
-
Christensen MO, Krokowski RM, Barthelmes HU, Hock R, Boege F, Mielke C (2004) Distinct effects of topoisomerase I and RNA polymerase I inhibitors suggest a dual mechanism of nucleolar/nucleoplasmic partitioning of topoisomerase I. J Biol Chem 279(21): 21873-21882
-
(2004)
J Biol Chem
, vol.279
, Issue.21
, pp. 21873-21882
-
-
Christensen, M.O.1
Krokowski, R.M.2
Barthelmes, H.U.3
Hock, R.4
Boege, F.5
Mielke, C.6
-
25
-
-
31144446588
-
Papillomavirus E1 protein binds to and stimulates human topoisomerase I
-
Clower RV, Fisk JC, Melendy T (2006a) Papillomavirus E1 protein binds to and stimulates human topoisomerase I. J Virol 80(3): 1584-1587
-
(2006)
J Virol
, vol.80
, Issue.3
, pp. 1584-1587
-
-
Clower, R.V.1
Fisk, J.C.2
Melendy, T.3
-
26
-
-
33646039334
-
Papillomavirus E2 protein interacts with and stimulates human topoisomerase I
-
Clower RV, Hu Y, Melendy T (2006b) Papillomavirus E2 protein interacts with and stimulates human topoisomerase I. Virology 348(1): 13-18
-
(2006)
Virology
, vol.348
, Issue.1
, pp. 13-18
-
-
Clower, R.V.1
Hu, Y.2
Melendy, T.3
-
27
-
-
34547498794
-
Fast dynamics of supercoiled DNA revealed by single-molecule experiments
-
Crut A, Koster DA, Seidel R, Wiggins CH, Dekker NH (2007) Fast dynamics of supercoiled DNA revealed by single-molecule experiments. Proc Natl Acad Sci USA 104(29): 11957-11962
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, Issue.29
, pp. 11957-11962
-
-
Crut, A.1
Koster, D.A.2
Seidel, R.3
Wiggins, C.H.4
Dekker, N.H.5
-
28
-
-
17444426290
-
Proteomic analysis of complexes formed by human topoisomerase I
-
Czubaty A, Girstun A, Kowalska-Loth B, Trzcinska AM, Purta E, Winczura A, Grajkowski W, Staron K (2005) Proteomic analysis of complexes formed by human topoisomerase I. Biochim Biophys Acta 1749(1): 133-141
-
(2005)
Biochim Biophys Acta
, vol.1749
, Issue.1
, pp. 133-141
-
-
Czubaty, A.1
Girstun, A.2
Kowalska-loth, B.3
Trzcinska, A.M.4
Purta, E.5
Winczura, A.6
Grajkowski, W.7
Staron, K.8
-
29
-
-
33644821060
-
The structure of the transition state of the heterodimeric topoisomerase I of Leishmania donovani as a vanadate complex with nicked DNA
-
Davies DR, Mushtaq A, Interthal H, Champoux JJ, Hol WG (2006) The structure of the transition state of the heterodimeric topoisomerase I of Leishmania donovani as a vanadate complex with nicked DNA. J Mol Biol 357(4): 1202-1210
-
(2006)
J Mol Biol
, vol.357
, Issue.4
, pp. 1202-1210
-
-
Davies, D.R.1
Mushtaq, A.2
Interthal, H.3
Champoux, J.J.4
Hol, W.G.5
-
30
-
-
0242290326
-
Single mutation in the linker domain confers protein flexibility and camptothecin resistance to human topoisomerase I
-
Fiorani P, Bruselles A, Falconi M, Chillemi G, Desideri A, Benedetti P (2003) Single mutation in the linker domain confers protein flexibility and camptothecin resistance to human topoisomerase I. J Biol Chem 278(44): 43268-43275
-
(2003)
J Biol Chem
, vol.278
, Issue.44
, pp. 43268-43275
-
-
Fiorani, P.1
Bruselles, A.2
Falconi, M.3
Chillemi, G.4
Desideri, A.5
Benedetti, P.6
-
31
-
-
73349101566
-
Evidence of the crucial role of the linker domain on the catalytic activity of human topoisomerase I by experimental and simulative characterization of the Lys681Ala mutant
-
Fiorani P, Tesauro C, Mancini G, Chillemi G, D'Annessa I, Graziani G, Tentori L, Muzi A, Desideri A (2009) Evidence of the crucial role of the linker domain on the catalytic activity of human topoisomerase I by experimental and simulative characterization of the Lys681Ala mutant. Nucleic Acids Res 37(20): 6849-6858
-
(2009)
Nucleic Acids Res
, vol.37
, Issue.20
, pp. 6849-6858
-
-
Fiorani, P.1
Tesauro, C.2
Mancini, G.3
Chillemi, G.4
D'Annessa, I.5
Graziani, G.6
Tentori, L.7
Muzi, A.8
Desideri, A.9
-
32
-
-
0343116845
-
Drosophila DNA topoisomerase I is associated with transcriptionally active regions of the genome
-
Fleischmann G, Pflugfelder G, Steiner EK, Javaherian K, Howard GC, Wang JC, Elgin SC (1984) Drosophila DNA topoisomerase I is associated with transcriptionally active regions of the genome. Proc Natl Acad Sci USA 81(22): 6958-6962
-
(1984)
Proc Natl Acad Sci USA
, vol.81
, Issue.22
, pp. 6958-6962
-
-
Fleischmann, G.1
Pflugfelder, G.2
Steiner, E.K.3
Javaherian, K.4
Howard, G.C.5
Wang, J.C.6
Elgin, S.C.7
-
33
-
-
0347130921
-
Regions within the N-terminal domain of human topoisomerase I exert important functions during strand rotation and DNA binding
-
Frohlich RF, Andersen FF, Westergaard O, Andersen AH, Knudsen BR (2004) Regions within the N-terminal domain of human topoisomerase I exert important functions during strand rotation and DNA binding. J Mol Biol 336(1): 93-103
-
(2004)
J Mol Biol
, vol.336
, Issue.1
, pp. 93-103
-
-
Frohlich, R.F.1
Andersen, F.F.2
Westergaard, O.3
Andersen, A.H.4
Knudsen, B.R.5
-
34
-
-
35548983057
-
Tryptophane-205 of human topoisomerase I is essential for camptothecin inhibition of negative but not positive supercoil removal
-
Frohlich RF, Veigaard C, Andersen FF, McClendon AK, Gentry AC, Andersen AH, Osheroff N, Stevnsner T, Knudsen BR (2007) Tryptophane-205 of human topoisomerase I is essential for camptothecin inhibition of negative but not positive supercoil removal. Nucleic Acids Res 35(18): 6170-6180
-
(2007)
Nucleic Acids Res
, vol.35
, Issue.18
, pp. 6170-6180
-
-
Frohlich, R.F.1
Veigaard, C.2
Andersen, F.F.3
McClendon, A.K.4
Gentry, A.C.5
Andersen, A.H.6
Osheroff, N.7
Stevnsner, T.8
Knudsen, B.R.9
-
35
-
-
0022508558
-
Topoisomerase I interacts with transcribed regions in Drosophila cells
-
Gilmour DS, Pflugfelder G, Wang JC, Lis JT (1986) Topoisomerase I interacts with transcribed regions in Drosophila cells. Cell 44(3): 401-407
-
(1986)
Cell
, vol.44
, Issue.3
, pp. 401-407
-
-
Gilmour, D.S.1
Pflugfelder, G.2
Wang, J.C.3
Lis, J.T.4
-
36
-
-
0029971854
-
Modulation of DNA topoisomerase I activity by p53
-
Gobert C, Bracco L, Rossi F, Olivier M, Tazi J, Lavelle F, Larsen AK, Riou JF (1996) Modulation of DNA topoisomerase I activity by p53. Biochemistry 35(18): 5778-5786
-
(1996)
Biochemistry
, vol.35
, Issue.18
, pp. 5778-5786
-
-
Gobert, C.1
Bracco, L.2
Rossi, F.3
Olivier, M.4
Tazi, J.5
Lavelle, F.6
Larsen, A.K.7
Riou, J.F.8
-
37
-
-
0033621189
-
The interaction between p53 and DNA topoisomerase I is regulated differently in cells with wild-type and mutant p53
-
Gobert C, Skladanowski A, Larsen AK (1999) The interaction between p53 and DNA topoisomerase I is regulated differently in cells with wild-type and mutant p53. Proc Natl Acad Sci USA 96(18): 10355-10360
-
(1999)
Proc Natl Acad Sci USA
, vol.96
, Issue.18
, pp. 10355-10360
-
-
Gobert, C.1
Skladanowski, A.2
Larsen, A.K.3
-
38
-
-
69249212321
-
Automated comparative protein structure modeling with SWISS-MODEL and Swiss-PdbViewer: A historical perspective
-
Guex N, Peitsch MC, Schwede T (2009) Automated comparative protein structure modeling with SWISS-MODEL and Swiss-PdbViewer: a historical perspective. Electrophoresis 30 Suppl 1: S162-173
-
(2009)
Electrophoresis
, vol.30
, pp. S162-S173
-
-
Guex, N.1
Peitsch, M.C.2
Schwede, T.3
-
39
-
-
47749138222
-
Mitotic phosphorylation stimulates DNA relaxation activity of human topoisomerase I
-
Hackbarth JS, Galvez-Peralta M, Dai NT, Loegering DA, Peterson KL, Meng XW, Karnitz LM, Kaufmann SH (2008) Mitotic phosphorylation stimulates DNA relaxation activity of human topoisomerase I. J Biol Chem 283(24): 16711-16722
-
(2008)
J Biol Chem
, vol.283
, Issue.24
, pp. 16711-16722
-
-
Hackbarth, J.S.1
Galvez-peralta, M.2
Dai, N.T.3
Loegering, D.A.4
Peterson, K.L.5
Meng, X.W.6
Karnitz, L.M.7
Kaufmann, S.H.8
-
40
-
-
2642694700
-
Interaction between the N-terminus of human topoisomerase I and SV40 large T antigen
-
Haluska P, Jr., Saleem A, Edwards TK, Rubin EH (1998) Interaction between the N-terminus of human topoisomerase I and SV40 large T antigen. Nucleic Acids Res 26(7): 1841-1847
-
(1998)
Nucleic Acids Res
, vol.26
, Issue.7
, pp. 1841-1847
-
-
Haluska, P.1
Saleem, A.2
Edwards, T.K.3
Rubin, E.H.4
-
41
-
-
0345298272
-
Interaction between human topoisomerase I and a novel RING finger/arginine-serine protein
-
Haluska P, Jr., Saleem A, Rasheed Z, Ahmed F, Su EW, Liu LF, Rubin EH (1999) Interaction between human topoisomerase I and a novel RING finger/arginine-serine protein. Nucleic Acids Res 27(12): 2538-2544
-
(1999)
Nucleic Acids Res
, vol.27
, Issue.12
, pp. 2538-2544
-
-
Haluska, P.1
Saleem, A.2
Rasheed, Z.3
Ahmed, F.4
Su, E.W.5
Liu, L.F.6
Rubin, E.H.7
-
42
-
-
36048929872
-
The E3 ligase Topors induces the accumulation of polysumoylated forms of DNA topoisomerase I in vitro and in vivo
-
Hammer E, Heilbronn R, Weger S (2007) The E3 ligase Topors induces the accumulation of polysumoylated forms of DNA topoisomerase I in vitro and in vivo. FEBS Lett 581(28): 5418-5424
-
(2007)
FEBS Lett
, vol.581
, Issue.28
, pp. 5418-5424
-
-
Hammer, E.1
Heilbronn, R.2
Weger, S.3
-
43
-
-
0034652329
-
Closing the ring: Links between SMC proteins and chromosome partitioning, condensation, and supercoiling
-
Holmes VF, Cozzarelli NR (2000) Closing the ring: links between SMC proteins and chromosome partitioning, condensation, and supercoiling. Proc Natl Acad Sci USA 97(4): 1322-1324
-
(2000)
Proc Natl Acad Sci USA
, vol.97
, Issue.4
, pp. 1322-1324
-
-
Holmes, V.F.1
Cozzarelli, N.R.2
-
44
-
-
0022340594
-
Camptothecin induces protein-linked DNA breaks via mammalian DNA topoisomerase I
-
Hsiang YH, Hertzberg R, Hecht S, Liu LF (1985) Camptothecin induces protein-linked DNA breaks via mammalian DNA topoisomerase I. J Biol Chem 260(27): 14873-14878
-
(1985)
J Biol Chem
, vol.260
, Issue.27
, pp. 14873-14878
-
-
Hsiang, Y.H.1
Hertzberg, R.2
Hecht, S.3
Liu, L.F.4
-
45
-
-
66249119737
-
A genetic screen identifies topoisomerase 1 as a regulator of senescence
-
Humbert N, Martien S, Augert A, Da Costa M, Mauen S, Abbadie C, de Launoit Y, Gil J, Bernard D (2009) A genetic screen identifies topoisomerase 1 as a regulator of senescence. Cancer Res 69(10): 4101-4106
-
(2009)
Cancer Res
, vol.69
, Issue.10
, pp. 4101-4106
-
-
Humbert, N.1
Martien, S.2
Augert, A.3
Da Costa, M.4
Mauen, S.5
Abbadie, C.6
de Launoit, Y.7
Gil, J.8
Bernard, D.9
-
46
-
-
1642453632
-
The role of lysine 532 in the catalytic mechanism of human topoisomerase I
-
Interthal H, Quigley PM, Hol WG, Champoux JJ (2004) The role of lysine 532 in the catalytic mechanism of human topoisomerase I. J Biol Chem 279(4): 2984-2992
-
(2004)
J Biol Chem
, vol.279
, Issue.4
, pp. 2984-2992
-
-
Interthal, H.1
Quigley, P.M.2
Hol, W.G.3
Champoux, J.J.4
-
47
-
-
0021111554
-
Association of eukaryotic DNA topoisomerase I with nucleosomes and chromosomal proteins
-
Javaherian K, Liu LF (1983) Association of eukaryotic DNA topoisomerase I with nucleosomes and chromosomal proteins. Nucleic Acids Res 11(2): 461-472
-
(1983)
Nucleic Acids Res
, vol.11
, Issue.2
, pp. 461-472
-
-
Javaherian, K.1
Liu, L.F.2
-
48
-
-
0025719903
-
Effect of local DNA sequence on topoisomerase I cleavage in the presence or absence of camptothecin
-
Jaxel C, Capranico G, Kerrigan D, Kohn KW, Pommier Y (1991) Effect of local DNA sequence on topoisomerase I cleavage in the presence or absence of camptothecin. J Biol Chem 266(30): 20418-20423
-
(1991)
J Biol Chem
, vol.266
, Issue.30
, pp. 20418-20423
-
-
Jaxel, C.1
Capranico, G.2
Kerrigan, D.3
Kohn, K.W.4
Pommier, Y.5
-
49
-
-
0035864758
-
Human ARF protein interacts with topoisomerase I and stimulates its activity
-
Karayan L, Riou JF, Seite P, Migeon J, Cantereau A, Larsen CJ (2001) Human ARF protein interacts with topoisomerase I and stimulates its activity. Oncogene 20(7): 836-848
-
(2001)
Oncogene
, vol.20
, Issue.7
, pp. 836-848
-
-
Karayan, L.1
Riou, J.F.2
Seite, P.3
Migeon, J.4
Cantereau, A.5
Larsen, C.J.6
-
50
-
-
0024338961
-
Function of DNA topoisomerases as replication swivels in Saccharomyces cerevisiae
-
Kim RA, Wang JC (1989) Function of DNA topoisomerases as replication swivels in Saccharomyces cerevisiae. J Mol Biol 208(2): 257-267
-
(1989)
J Mol Biol
, vol.208
, Issue.2
, pp. 257-267
-
-
Kim, R.A.1
Wang, J.C.2
-
51
-
-
0033597962
-
13S condensin actively reconfigures DNA by introducing global positive writhe: Implications for chromosome condensation
-
Kimura K, Rybenkov VV, Crisona NJ, Hirano T, Cozzarelli NR (1999) 13S condensin actively reconfigures DNA by introducing global positive writhe: implications for chromosome condensation. Cell 98(2): 239-248
-
(1999)
Cell
, vol.98
, Issue.2
, pp. 239-248
-
-
Kimura, K.1
Rybenkov, V.V.2
Crisona, N.J.3
Hirano, T.4
Cozzarelli, N.R.5
-
52
-
-
0034570196
-
How do drug-induced topoisomerase I-DNA lesions signal to the molecular interaction network that regulates cell cycle checkpoints, DNA replication, and DNA repair?
-
Kohn KW, Shao RG, Pommier Y (2000) How do drug-induced topoisomerase I-DNA lesions signal to the molecular interaction network that regulates cell cycle checkpoints, DNA replication, and DNA repair? Cell Biochem Biophys 33(2): 175-180
-
(2000)
Cell Biochem Biophys
, vol.33
, Issue.2
, pp. 175-180
-
-
Kohn, K.W.1
Shao, R.G.2
Pommier, Y.3
-
53
-
-
15844383117
-
Friction and torque govern the relaxation of DNA supercoils by eukaryotic topoisomerase IB
-
Koster DA, Croquette V, Dekker C, Shuman S, Dekker NH (2005) Friction and torque govern the relaxation of DNA supercoils by eukaryotic topoisomerase IB. Nature 434(7033): 671-674
-
(2005)
Nature
, vol.434
, Issue.7033
, pp. 671-674
-
-
Koster, D.A.1
Croquette, V.2
Dekker, C.3
Shuman, S.4
Dekker, N.H.5
-
54
-
-
34447509295
-
Antitumour drugs impede DNA uncoiling by topoisomerase I
-
Koster DA, Palle K, Bot ES, Bjornsti MA, Dekker NH (2007) Antitumour drugs impede DNA uncoiling by topoisomerase I. Nature 448(7150): 213-217
-
(2007)
Nature
, vol.448
, Issue.7150
, pp. 213-217
-
-
Koster, D.A.1
Palle, K.2
Bot, E.S.3
Bjornsti, M.A.4
Dekker, N.H.5
-
55
-
-
0037503634
-
Activation of human topoisomerase I by protein kinase CK2
-
Kowalska-Loth B, Girstun A, Derlacz R, Staron K (2003) Activation of human topoisomerase I by protein kinase CK2. Mol Biol Rep 30(2): 107-111
-
(2003)
Mol Biol Rep
, vol.30
, Issue.2
, pp. 107-111
-
-
Kowalska-loth, B.1
Girstun, A.2
Derlacz, R.3
Staron, K.4
-
56
-
-
0027138674
-
Identification of human DNA topoisomerase I as a cofactor for activator-dependent transcription by RNA polymerase II
-
Kretzschmar M, Meisterernst M, Roeder RG (1993) Identification of human DNA topoisomerase I as a cofactor for activator-dependent transcription by RNA polymerase II. Proc Natl Acad Sci USA 90(24): 11508-11512
-
(1993)
Proc Natl Acad Sci USA
, vol.90
, Issue.24
, pp. 11508-11512
-
-
Kretzschmar, M.1
Meisterernst, M.2
Roeder, R.G.3
-
57
-
-
0024431084
-
Interaction of topoisomerase 1 with the transcribed region of the Drosophila HSP 70 heat shock gene
-
Kroeger PE, Rowe TC (1989) Interaction of topoisomerase 1 with the transcribed region of the Drosophila HSP 70 heat shock gene. Nucleic Acids Res 17(21): 8495-8509
-
(1989)
Nucleic Acids Res
, vol.17
, Issue.21
, pp. 8495-8509
-
-
Kroeger, P.E.1
Rowe, T.C.2
-
58
-
-
0032526604
-
Interaction between the N-terminal domain of human DNA topoisomerase I and the arginine-serine domain of its substrate determines phosphorylation of SF2/ASF splicing factor
-
Labourier E, Rossi F, Gallouzi IE, Allemand E, Divita G, Tazi J (1998) Interaction between the N-terminal domain of human DNA topoisomerase I and the arginine-serine domain of its substrate determines phosphorylation of SF2/ASF splicing factor. Nucleic Acids Res 26(12): 2955-2962
-
(1998)
Nucleic Acids Res
, vol.26
, Issue.12
, pp. 2955-2962
-
-
Labourier, E.1
Rossi, F.2
Gallouzi, I.E.3
Allemand, E.4
Divita, G.5
Tazi, J.6
-
59
-
-
0242694944
-
Werner protein stimulates topoisomerase I DNA relaxation activity
-
Laine JP, Opresko PL, Indig FE, Harrigan JA, von Kobbe C, Bohr VA (2003) Werner protein stimulates topoisomerase I DNA relaxation activity. Cancer Res 63(21): 7136-7146
-
(2003)
Cancer Res
, vol.63
, Issue.21
, pp. 7136-7146
-
-
Laine, J.P.1
Opresko, P.L.2
Indig, F.E.3
Harrigan, J.A.4
von Kobbe, C.5
Bohr, V.A.6
-
60
-
-
0032759443
-
DNA topoisomerase I in oncology: Dr Jekyll or Mr Hyde?
-
Larsen AK, Gobert C (1999) DNA topoisomerase I in oncology: Dr Jekyll or Mr Hyde? Pathol Oncol Res 5(3): 171-178
-
(1999)
Pathol Oncol Res
, vol.5
, Issue.3
, pp. 171-178
-
-
Larsen, A.K.1
Gobert, C.2
-
61
-
-
0032253818
-
DNA topoisomerases as repair enzymes: Mechanism(s) of action and regulation by p53
-
Larsen AK, Gobert C, Gilbert C, Markovits J, Bojanowski K, Skladanowski A (1998) DNA topoisomerases as repair enzymes: mechanism(s) of action and regulation by p53. Acta Biochim Pol 45(2): 535-544
-
(1998)
Acta Biochim Pol
, vol.45
, Issue.2
, pp. 535-544
-
-
Larsen, A.K.1
Gobert, C.2
Gilbert, C.3
Markovits, J.4
Bojanowski, K.5
Skladanowski, A.6
-
62
-
-
42149171249
-
Trapping of human DNA topoisomerase I by DNA structures mimicking intermediates of DNA repair
-
Lebedeva N, Rechkunova N, Boiteux S, Lavrik O (2008) Trapping of human DNA topoisomerase I by DNA structures mimicking intermediates of DNA repair. IUBMB Life 60(2): 130-134
-
(2008)
IUBMB Life
, vol.60
, Issue.2
, pp. 130-134
-
-
Lebedeva, N.1
Rechkunova, N.2
Boiteux, S.3
Lavrik, O.4
-
63
-
-
0033621354
-
The Werner syndrome gene product co-purifies with the DNA replication complex and interacts with PCNA and topoisomerase I
-
Lebel M, Spillare EA, Harris CC, Leder P (1999) The Werner syndrome gene product co-purifies with the DNA replication complex and interacts with PCNA and topoisomerase I. J Biol Chem 274(53): 37795-37799
-
(1999)
J Biol Chem
, vol.274
, Issue.53
, pp. 37795-37799
-
-
Lebel, M.1
Spillare, E.A.2
Harris, C.C.3
Leder, P.4
-
64
-
-
0027165312
-
DNA topoisomerase I is essential in Drosophila melanogaster
-
Lee MP, Brown SD, Chen A, Hsieh TS (1993) DNA topoisomerase I is essential in Drosophila melanogaster. Proc Natl Acad Sci USA 90(14): 6656-6660
-
(1993)
Proc Natl Acad Sci USA
, vol.90
, Issue.14
, pp. 6656-6660
-
-
Lee, M.P.1
Brown, S.D.2
Chen, A.3
Hsieh, T.S.4
-
65
-
-
0037047088
-
Potent stimulation of transcription-coupled DNA supercoiling by sequence-specific DNA-binding proteins
-
Leng F, McMacken R (2002) Potent stimulation of transcription-coupled DNA supercoiling by sequence-specific DNA-binding proteins. Proc Natl Acad Sci USA 99(14): 9139-9144
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, Issue.14
, pp. 9139-9144
-
-
Leng, F.1
McMacken, R.2
-
66
-
-
22744457037
-
Human DNA topoisomerase I: Relaxation, roles, and damage control
-
Leppard JB, Champoux JJ (2005) Human DNA topoisomerase I: relaxation, roles, and damage control. Chromosoma 114(2): 75-85
-
(2005)
Chromosoma
, vol.114
, Issue.2
, pp. 75-85
-
-
Leppard, J.B.1
Champoux, J.J.2
-
67
-
-
0035827562
-
Residues within the N-terminal domain of human topoisomerase I play a direct role in relaxation
-
Lisby M, Olesen JR, Skouboe C, Krogh BO, Straub T, Boege F, Velmurugan S, Martensen PM, Andersen AH, Jayaram M, Westergaard O, Knudsen BR (2001) Residues within the N-terminal domain of human topoisomerase I play a direct role in relaxation. J Biol Chem 276(23): 20220-20227
-
(2001)
J Biol Chem
, vol.276
, Issue.23
, pp. 20220-20227
-
-
Lisby, M.1
Olesen, J.R.2
Skouboe, C.3
Krogh, B.O.4
Straub, T.5
Boege, F.6
Velmurugan, S.7
Martensen, P.M.8
Andersen, A.H.9
Jayaram, M.10
Westergaard, O.11
Knudsen, B.R.12
-
68
-
-
0023433855
-
Supercoiling of the DNA template during transcription
-
Liu LF, Wang JC (1987) Supercoiling of the DNA template during transcription. Proc Natl Acad Sci USA 84(20): 7024-7027
-
(1987)
Proc Natl Acad Sci USA
, vol.84
, Issue.20
, pp. 7024-7027
-
-
Liu, L.F.1
Wang, J.C.2
-
69
-
-
34248147699
-
Alterations in linker flexibility suppress DNA topoisomerase I mutant-induced cell lethality
-
Losasso C, Cretaio E, Palle K, Pattarello L, Bjornsti MA, Benedetti P (2007) Alterations in linker flexibility suppress DNA topoisomerase I mutant-induced cell lethality. J Biol Chem 282(13): 9855-9864
-
(2007)
J Biol Chem
, vol.282
, Issue.13
, pp. 9855-9864
-
-
Losasso, C.1
Cretaio, E.2
Palle, K.3
Pattarello, L.4
Bjornsti, M.A.5
Benedetti, P.6
-
70
-
-
0028787255
-
Preferential binding of human topoisomerase I to superhelical DNA
-
Madden KR, Stewart L, Champoux JJ (1995) Preferential binding of human topoisomerase I to superhelical DNA. EMBO J 14(21): 5399-5409
-
(1995)
EMBO J
, vol.14
, Issue.21
, pp. 5399-5409
-
-
Madden, K.R.1
Stewart, L.2
Champoux, J.J.3
-
71
-
-
1242339684
-
Poly(ADP-ribose) reactivates stalled DNA topoisomerase I and Induces DNA strand break resealing
-
Malanga M, Althaus FR (2004) Poly(ADP-ribose) reactivates stalled DNA topoisomerase I and Induces DNA strand break resealing. J Biol Chem 279(7): 5244-5248
-
(2004)
J Biol Chem
, vol.279
, Issue.7
, pp. 5244-5248
-
-
Malanga, M.1
Althaus, F.R.2
-
72
-
-
0037022269
-
Subnuclear distribution of topoisomerase I is linked to ongoing transcription and p53 status
-
Mao Y, Mehl IR, Muller MT (2002) Subnuclear distribution of topoisomerase I is linked to ongoing transcription and p53 status. Proc Natl Acad Sci USA 99(3): 1235-1240
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, Issue.3
, pp. 1235-1240
-
-
Mao, Y.1
Mehl, I.R.2
Muller, M.T.3
-
73
-
-
0034635958
-
SUMO-1 conjugation to topoisomerase I: A possible repair response to topoisomerase-mediated DNA damage
-
Mao Y, Sun M, Desai SD, Liu LF (2000) SUMO-1 conjugation to topoisomerase I: A possible repair response to topoisomerase-mediated DNA damage. Proc Natl Acad Sci USA 97(8): 4046-4051
-
(2000)
Proc Natl Acad Sci USA
, vol.97
, Issue.8
, pp. 4046-4051
-
-
Mao, Y.1
Sun, M.2
Desai, S.D.3
Liu, L.F.4
-
74
-
-
0027186443
-
DNA topoisomerase I is involved in both repression and activation of transcription
-
Merino A, Madden KR, Lane WS, Champoux JJ, Reinberg D (1993) DNA topoisomerase I is involved in both repression and activation of transcription. Nature 365(6443): 227-232
-
(1993)
Nature
, vol.365
, Issue.6443
, pp. 227-232
-
-
Merino, A.1
Madden, K.R.2
Lane, W.S.3
Champoux, J.J.4
Reinberg, D.5
-
75
-
-
20344400134
-
DNA topoisomerase I is a cofactor for c-Jun in the regulation of epidermal growth factor receptor expression and cancer cell proliferation
-
Mialon A, Sankinen M, Soderstrom H, Junttila TT, Holmstrom T, Koivusalo R, Papageorgiou AC, Johnson RS, Hietanen S, Elenius K, Westermarck J (2005) DNA topoisomerase I is a cofactor for c-Jun in the regulation of epidermal growth factor receptor expression and cancer cell proliferation. Mol Cell Biol 25(12): 5040-5051
-
(2005)
Mol Cell Biol
, vol.25
, Issue.12
, pp. 5040-5051
-
-
Mialon, A.1
Sankinen, M.2
Soderstrom, H.3
Junttila, T.T.4
Holmstrom, T.5
Koivusalo, R.6
Papageorgiou, A.C.7
Johnson, R.S.8
Hietanen, S.9
Elenius, K.10
Westermarck, J.11
-
76
-
-
34548763143
-
Nonclassic functions of human topoisomerase I: Genome-wide and pharmacologic analyses
-
Miao ZH, Player A, Shankavaram U, Wang YH, Zimonjic DB, Lorenzi PL, Liao ZY, Liu H, Shimura T, Zhang HL, Meng LH, Zhang YW, Kawasaki ES, Popescu NC, Aladjem MI, Goldstein DJ, Weinstein JN, Pommier Y (2007) Nonclassic functions of human topoisomerase I: genome-wide and pharmacologic analyses. Cancer Res 67(18): 8752-8761
-
(2007)
Cancer Res
, vol.67
, Issue.18
, pp. 8752-8761
-
-
Miao, Z.H.1
Player, A.2
Shankavaram, U.3
Wang, Y.H.4
Zimonjic, D.B.5
Lorenzi, P.L.6
Liao, Z.Y.7
Liu, H.8
Shimura, T.9
Zhang, H.L.10
Meng, L.H.11
Zhang, Y.W.12
Kawasaki, E.S.13
Popescu, N.C.14
Aladjem, M.I.15
Goldstein, D.J.16
Weinstein, J.N.17
Pommier, Y.18
-
77
-
-
0034731326
-
A novel nuclear localization signal in human DNA topoisomerase I
-
Mo YY, Wang C, Beck WT (2000) A novel nuclear localization signal in human DNA topoisomerase I. J Biol Chem 275(52): 41107-41113
-
(2000)
J Biol Chem
, vol.275
, Issue.52
, pp. 41107-41113
-
-
Mo, Y.Y.1
Wang, C.2
Beck, W.T.3
-
78
-
-
0029912651
-
Targeted disruption of the mouse topoisomerase I gene by camptothecin selection
-
Morham SG, Kluckman KD, Voulomanos N, Smithies O (1996) Targeted disruption of the mouse topoisomerase I gene by camptothecin selection. Mol Cell Biol 16(12): 6804-6809
-
(1996)
Mol Cell Biol
, vol.16
, Issue.12
, pp. 6804-6809
-
-
Morham, S.G.1
Kluckman, K.D.2
Voulomanos, N.3
Smithies, O.4
-
80
-
-
0022067647
-
Eukaryotic type I topoisomerase is enriched in the nucleolus and catalytically active on ribosomal DNA
-
Muller MT, Pfund WP, Mehta VB, Trask DK (1985) Eukaryotic type I topoisomerase is enriched in the nucleolus and catalytically active on ribosomal DNA. Embo J 4(5): 1237-1243
-
(1985)
Embo J
, vol.4
, Issue.5
, pp. 1237-1243
-
-
Muller, M.T.1
Pfund, W.P.2
Mehta, V.B.3
Trask, D.K.4
-
81
-
-
0033405042
-
Transport of torsional stress in DNA
-
Nelson P (1999) Transport of torsional stress in DNA. Proc Natl Acad Sci USA 96(25): 14342-14347
-
(1999)
Proc Natl Acad Sci USA
, vol.96
, Issue.25
, pp. 14342-14347
-
-
Nelson, P.1
-
82
-
-
18144373451
-
Poly(ADP-ribose) polymerase-1 could facilitate the religation of topoisomerase I-linked DNA inhibited by camptothecin
-
Park SY, Cheng YC (2005) Poly(ADP-ribose) polymerase-1 could facilitate the religation of topoisomerase I-linked DNA inhibited by camptothecin. Cancer Res 65(9): 3894-3902
-
(2005)
Cancer Res
, vol.65
, Issue.9
, pp. 3894-3902
-
-
Park, S.Y.1
Cheng, Y.C.2
-
83
-
-
8844239149
-
The topoisomerase 1-interacting protein BTBD1 is essential for muscle cell differentiation
-
Pisani DF, Cabane C, Derijard B, Dechesne CA (2004) The topoisomerase 1-interacting protein BTBD1 is essential for muscle cell differentiation. Cell Death Differ 11(11): 1157-1165
-
(2004)
Cell Death Differ
, vol.11
, Issue.11
, pp. 1157-1165
-
-
Pisani, D.F.1
Cabane, C.2
Derijard, B.3
Dechesne, C.A.4
-
84
-
-
33745278845
-
Repair of topoisomerase I-mediated DNA damage
-
Pommier Y, Barcelo JM, Rao VA, Sordet O, Jobson AG, Thibaut L, Miao ZH, Seiler JA, Zhang H, Marchand C, Agama K, Nitiss JL, Redon C (2006) Repair of topoisomerase I-mediated DNA damage. Prog Nucleic Acid Res Mol Biol 81: 179-229
-
(2006)
Prog Nucleic Acid Res Mol Biol
, vol.81
, pp. 179-229
-
-
Pommier, Y.1
Barcelo, J.M.2
Rao, V.A.3
Sordet, O.4
Jobson, A.G.5
Thibaut, L.6
Miao, Z.H.7
Seiler, J.A.8
Zhang, H.9
Marchand, C.10
Agama, K.11
Nitiss, J.L.12
Redon, C.13
-
85
-
-
14644420930
-
Interfacial inhibition of macromolecular interactions: Nature's paradigm for drug discovery
-
Pommier Y, Cherfils J (2005) Interfacial inhibition of macromolecular interactions: nature's paradigm for drug discovery. Trends Pharmacol Sci 26(3): 138-145
-
(2005)
Trends Pharmacol Sci
, vol.26
, Issue.3
, pp. 138-145
-
-
Pommier, Y.1
Cherfils, J.2
-
86
-
-
0032189683
-
Mechanism of action of eukaryotic DNA topoisomerase I and drugs targeted to the enzyme
-
Pommier Y, Pourquier P, Fan Y, Strumberg D (1998) Mechanism of action of eukaryotic DNA topoisomerase I and drugs targeted to the enzyme. Biochim Biophys Acta 1400(1-3): 83-105
-
(1998)
Biochim Biophys Acta
, vol.1400
, Issue.1-3
, pp. 83-105
-
-
Pommier, Y.1
Pourquier, P.2
Fan, Y.3
Strumberg, D.4
-
87
-
-
10744233671
-
Repair of and checkpoint response to topoisomerase I-mediated DNA damage
-
Pommier Y, Redon C, Rao VA, Seiler JA, Sordet O, Takemura H, Antony S, Meng L, Liao Z, Kohlhagen G, Zhang H, Kohn KW (2003) Repair of and checkpoint response to topoisomerase I-mediated DNA damage. Mutat Res 532(1-2): 173-203
-
(2003)
Mutat Res
, vol.532
, Issue.1-2
, pp. 173-203
-
-
Pommier, Y.1
Redon, C.2
Rao, V.A.3
Seiler, J.A.4
Sordet, O.5
Takemura, H.6
Antony, S.7
Meng, L.8
Liao, Z.9
Kohlhagen, G.10
Zhang, H.11
Kohn, K.W.12
-
88
-
-
0024469050
-
The basis for camptothecin enhancement of DNA breakage by eukaryotic topoisomerase I
-
Porter SE, Champoux JJ (1989) The basis for camptothecin enhancement of DNA breakage by eukaryotic topoisomerase I. Nucleic Acids Res 17(21): 8521-8532
-
(1989)
Nucleic Acids Res
, vol.17
, Issue.21
, pp. 8521-8532
-
-
Porter, S.E.1
Champoux, J.J.2
-
89
-
-
0034643810
-
Novel Insights into Catalytic Mechanism from a Crystal Structure of Human Topoisomerase I in Complex with DNA
-
Redinbo MR, Champoux JJ, Hol WG (2000) Novel Insights into Catalytic Mechanism from a Crystal Structure of Human Topoisomerase I in Complex with DNA. Biochemistry 39(23): 6832-6840
-
(2000)
Biochemistry
, vol.39
, Issue.23
, pp. 6832-6840
-
-
Redinbo, M.R.1
Champoux, J.J.2
Hol, W.G.3
-
90
-
-
0000734623
-
Structural flexibility in human topoisomerase I revealed in multiple non-isomorphous crystal structures
-
Redinbo MR, Stewart L, Champoux JJ, Hol WG (1999) Structural flexibility in human topoisomerase I revealed in multiple non-isomorphous crystal structures. J Mol Biol 292(3): 685-696
-
(1999)
J Mol Biol
, vol.292
, Issue.3
, pp. 685-696
-
-
Redinbo, M.R.1
Stewart, L.2
Champoux, J.J.3
Hol, W.G.4
-
91
-
-
0032489634
-
Crystal structures of human topoisomerase I in covalent and noncovalent complexes with DNA
-
Redinbo MR, Stewart L, Kuhn P, Champoux JJ, Hol WG (1998) Crystal structures of human topoisomerase I in covalent and noncovalent complexes with DNA. Science 279(5356): 1504-1513
-
(1998)
Science
, vol.279
, Issue.5356
, pp. 1504-1513
-
-
Redinbo, M.R.1
Stewart, L.2
Kuhn, P.3
Champoux, J.J.4
Hol, W.G.5
-
92
-
-
0021760689
-
Structure of the nucleosome core particle at 7 A resolution
-
Richmond TJ, Finch JT, Rushton B, Rhodes D, Klug A (1984) Structure of the nucleosome core particle at 7 A resolution. Nature 311(5986): 532-537
-
(1984)
Nature
, vol.311
, Issue.5986
, pp. 532-537
-
-
Richmond, T.J.1
Finch, J.T.2
Rushton, B.3
Rhodes, D.4
Klug, A.5
-
93
-
-
33846102234
-
Cellular stress triggers the human topoisomerase I damage response independently of DNA damage in a p53 controlled manner
-
Rockstroh A, Kleinert A, Kramer M, Grosse F, Soe K (2007) Cellular stress triggers the human topoisomerase I damage response independently of DNA damage in a p53 controlled manner. Oncogene 26(1): 123-131
-
(2007)
Oncogene
, vol.26
, Issue.1
, pp. 123-131
-
-
Rockstroh, A.1
Kleinert, A.2
Kramer, M.3
Grosse, F.4
Soe, K.5
-
94
-
-
0023805882
-
Association of DNA topoisomerase I and RNA polymerase I: A possible role for topoisomerase I in ribosomal gene transcription
-
Rose KM, Szopa J, Han FS, Cheng YC, Richter A, Scheer U (1988) Association of DNA topoisomerase I and RNA polymerase I: a possible role for topoisomerase I in ribosomal gene transcription. Chromosoma 96(6): 411-416
-
(1988)
Chromosoma
, vol.96
, Issue.6
, pp. 411-416
-
-
Rose, K.M.1
Szopa, J.2
Han, F.S.3
Cheng, Y.C.4
Richter, A.5
Scheer, U.6
-
95
-
-
33745762610
-
Topoisomerase II, not topoisomerase I, is the proficient relaxase of nucleosomal DNA
-
Salceda J, Fernandez X, Roca J (2006) Topoisomerase II, not topoisomerase I, is the proficient relaxase of nucleosomal DNA. Embo J 25(11): 2575-2583
-
(2006)
Embo J
, vol.25
, Issue.11
, pp. 2575-2583
-
-
Salceda, J.1
Fernandez, X.2
Roca, J.3
-
96
-
-
29144455886
-
Rotation of DNA around intact strand in human topoisomerase I implies distinct mechanisms for positive and negative supercoil relaxation
-
Sari L, Andricioaei I (2005) Rotation of DNA around intact strand in human topoisomerase I implies distinct mechanisms for positive and negative supercoil relaxation. Nucleic Acids Res 33(20): 6621-6634
-
(2005)
Nucleic Acids Res
, vol.33
, Issue.20
, pp. 6621-6634
-
-
Sari, L.1
Andricioaei, I.2
-
97
-
-
0037180432
-
The mechanism of topoisomerase I poisoning by a camptothecin analog
-
Staker BL, Hjerrild K, Feese MD, Behnke CA, Burgin AB, Jr., Stewart L (2002) The mechanism of topoisomerase I poisoning by a camptothecin analog. Proc Natl Acad Sci USA 99(24): 15387-15392
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, Issue.24
, pp. 15387-15392
-
-
Staker, B.L.1
Hjerrild, K.2
Feese, M.D.3
Behnke, C.A.4
Burgin, A.B.5
Stewart, L.6
-
98
-
-
0025190947
-
Rapid induction of c-fos transcription reveals quantitative linkage of RNA polymerase II and DNA topoisomerase I enzyme activities
-
Stewart AF, Herrera RE, Nordheim A (1990) Rapid induction of c-fos transcription reveals quantitative linkage of RNA polymerase II and DNA topoisomerase I enzyme activities. Cell 60(1): 141-149
-
(1990)
Cell
, vol.60
, Issue.1
, pp. 141-149
-
-
Stewart, A.F.1
Herrera, R.E.2
Nordheim, A.3
-
99
-
-
0029869828
-
The domain organization of human topoisomerase I
-
Stewart L, Ireton GC, Champoux JJ (1996) The domain organization of human topoisomerase I. J Biol Chem 271(13): 7602-7608
-
(1996)
J Biol Chem
, vol.271
, Issue.13
, pp. 7602-7608
-
-
Stewart, L.1
Ireton, G.C.2
Champoux, J.J.3
-
100
-
-
0031566428
-
Reconstitution of human topoisomerase I by fragment complementation
-
Stewart L, Ireton GC, Champoux JJ (1997) Reconstitution of human topoisomerase I by fragment complementation. J Mol Biol 269(3): 355-372
-
(1997)
J Mol Biol
, vol.269
, Issue.3
, pp. 355-372
-
-
Stewart, L.1
Ireton, G.C.2
Champoux, J.J.3
-
101
-
-
0032752373
-
A functional linker in human topoisomerase I is required for maximum sensitivity to camptothecin in a DNA relaxation assay
-
Stewart L, Ireton GC, Champoux JJ (1999) A functional linker in human topoisomerase I is required for maximum sensitivity to camptothecin in a DNA relaxation assay. J Biol Chem 274(46): 32950-32960
-
(1999)
J Biol Chem
, vol.274
, Issue.46
, pp. 32950-32960
-
-
Stewart, L.1
Ireton, G.C.2
Champoux, J.J.3
-
102
-
-
0032489675
-
A model for the mechanism of human topoisomerase I
-
Stewart L, Redinbo MR, Qiu X, Hol WG, Champoux JJ (1998) A model for the mechanism of human topoisomerase I. Science 279(5356): 1534-1541
-
(1998)
Science
, vol.279
, Issue.5356
, pp. 1534-1541
-
-
Stewart, L.1
Redinbo, M.R.2
Qiu, X.3
Hol, W.G.4
Champoux, J.J.5
-
103
-
-
0028091124
-
Vaccinia DNA topoisomerase I: Single-turnover and steady-state kinetic analysis of the DNA strand cleavage and ligation reactions
-
Stivers JT, Shuman S, Mildvan AS (1994) Vaccinia DNA topoisomerase I: single-turnover and steady-state kinetic analysis of the DNA strand cleavage and ligation reactions. Biochemistry 33(1): 327-339
-
(1994)
Biochemistry
, vol.33
, Issue.1
, pp. 327-339
-
-
Stivers, J.T.1
Shuman, S.2
Mildvan, A.S.3
-
104
-
-
0032500516
-
The RNA-splicing factor PSF/p54 controls DNA-topoisomerase I activity by a direct interaction
-
Straub T, Grue P, Uhse A, Lisby M, Knudsen BR, Tange TO, Westergaard O, Boege F (1998) The RNA-splicing factor PSF/p54 controls DNA-topoisomerase I activity by a direct interaction. J Biol Chem 273(41): 26261-26264
-
(1998)
J Biol Chem
, vol.273
, Issue.41
, pp. 26261-26264
-
-
Straub, T.1
Grue, P.2
Uhse, A.3
Lisby, M.4
Knudsen, B.R.5
Tange, T.O.6
Westergaard, O.7
Boege, F.8
-
105
-
-
0034630945
-
HTLV-1 tax oncoprotein binds to DNA topoisomerase I and inhibits its catalytic activity
-
Suzuki T, Uchida-Toita M, Andoh T, Yoshida M (2000) HTLV-1 tax oncoprotein binds to DNA topoisomerase I and inhibits its catalytic activity. Virology 270(2): 291-298
-
(2000)
Virology
, vol.270
, Issue.2
, pp. 291-298
-
-
Suzuki, T.1
Uchida-toita, M.2
Andoh, T.3
Yoshida, M.4
-
106
-
-
0027501814
-
Induction of cleavage in topoisomerase I c-DNA by topoisomerase I enzymes from calf thymus and wheat germ in the presence and absence of camptothecin
-
Tanizawa A, Kohn KW, Pommier Y (1993) Induction of cleavage in topoisomerase I c-DNA by topoisomerase I enzymes from calf thymus and wheat germ in the presence and absence of camptothecin. Nucleic Acids Res 21(22): 5157-5166
-
(1993)
Nucleic Acids Res
, vol.21
, Issue.22
, pp. 5157-5166
-
-
Tanizawa, A.1
Kohn, K.W.2
Pommier, Y.3
-
107
-
-
19044400932
-
Rotational drag on DNA: A single molecule experiment
-
Thomen P, Bockelmann U, Heslot F (2002) Rotational drag on DNA: a single molecule experiment. Phys Rev Lett 88(24): 248102
-
(2002)
Phys Rev Lett
, vol.88
, Issue.24
, pp. 248102
-
-
Thomen, P.1
Bockelmann, U.2
Heslot, F.3
-
108
-
-
0021891888
-
DNA topoisomerases
-
Wang JC (1985) DNA topoisomerases. Annu Rev Biochem 54: 665-697
-
(1985)
Annu Rev Biochem
, vol.54
, pp. 665-697
-
-
Wang, J.C.1
-
109
-
-
0030014783
-
DNA Topoisomerases
-
Wang JC (1996) DNA Topoisomerases. Ann Rev Biochem 65: 635-692
-
(1996)
Ann Rev Biochem
, vol.65
, pp. 635-692
-
-
Wang, J.C.1
-
110
-
-
0036085460
-
Cellular roles of DNA topoisomerases: A molecular perspective
-
Wang JC (2002) Cellular roles of DNA topoisomerases: a molecular perspective. Nat Rev Mol Cell Biol 3(6): 430-440
-
(2002)
Nat Rev Mol Cell Biol
, vol.3
, Issue.6
, pp. 430-440
-
-
Wang, J.C.1
-
111
-
-
0344702740
-
Locking the DNA topoisomerase I protein clamp inhibits DNA rotation and induces cell lethality
-
Woo MH, Losasso C, Guo H, Pattarello L, Benedetti P, Bjornsti MA (2003) Locking the DNA topoisomerase I protein clamp inhibits DNA rotation and induces cell lethality. Proc Natl Acad Sci USA 100(24): 13767-13772
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, Issue.24
, pp. 13767-13772
-
-
Woo, M.H.1
Losasso, C.2
Guo, H.3
Pattarello, L.4
Benedetti, P.5
Bjornsti, M.A.6
-
112
-
-
77953617720
-
The phosphoCTD-interacting domain of Topoisomerase I
-
Wu J, Phatnani HP, Hsieh TS, Greenleaf AL (2010) The phosphoCTD-interacting domain of Topoisomerase I. Biochem Biophys Res Commun 397(1): 117-119
-
(2010)
Biochem Biophys Res Commun
, vol.397
, Issue.1
, pp. 117-119
-
-
Wu, J.1
Phatnani, H.P.2
Hsieh, T.S.3
Greenleaf, A.L.4
-
113
-
-
0028209137
-
A 17 S multiprotein form of murine cell DNA polymerase mediates polyomavirus DNA replication in vitro
-
Wu Y, Hickey R, Lawlor K, Wills P, Yu F, Ozer H, Starr R, Quan JY, Lee M, Malkas L (1994) A 17 S multiprotein form of murine cell DNA polymerase mediates polyomavirus DNA replication in vitro. J Cell Biochem 54(1): 32-46
-
(1994)
J Cell Biochem
, vol.54
, Issue.1
, pp. 32-46
-
-
Wu, Y.1
Hickey, R.2
Lawlor, K.3
Wills, P.4
Yu, F.5
Ozer, H.6
Starr, R.7
Quan, J.Y.8
Lee, M.9
Malkas, L.10
-
114
-
-
0037495636
-
Characterization of BTBD1 and BTBD2, two similar BTB-domain-containing Kelch-like proteins that interact with Topoisomerase I
-
Xu L, Yang L, Hashimoto K, Anderson M, Kohlhagen G, Pommier Y, D'Arpa P (2002) Characterization of BTBD1 and BTBD2, two similar BTB-domain-containing Kelch-like proteins that interact with Topoisomerase I. BMC Genomics 3(1): 1
-
(2002)
BMC Genomics
, vol.3
, Issue.1
, pp. 1
-
-
Xu, L.1
Yang, L.2
Hashimoto, K.3
Anderson, M.4
Kohlhagen, G.5
Pommier, Y.6
D'Arpa, P.7
-
115
-
-
2642625363
-
Roles of DNA topoisomerases in simian virus 40 DNA replication in vitro
-
Yang L, Wold MS, Li JJ, Kelly TJ, Liu LF (1987) Roles of DNA topoisomerases in simian virus 40 DNA replication in vitro. Proc Natl Acad Sci USA 84(4): 950-954
-
(1987)
Proc Natl Acad Sci USA
, vol.84
, Issue.4
, pp. 950-954
-
-
Yang, L.1
Wold, M.S.2
Li, J.J.3
Kelly, T.J.4
Liu, L.F.5
-
116
-
-
70349481519
-
Mutational analysis of the preferential binding of human topoisomerase I to supercoiled DNA
-
Yang Z, Carey JF, Champoux JJ (2009) Mutational analysis of the preferential binding of human topoisomerase I to supercoiled DNA. Febs J 276(20): 5906-5919
-
(2009)
Febs J
, vol.276
, Issue.20
, pp. 5906-5919
-
-
Yang, Z.1
Carey, J.F.2
Champoux, J.J.3
-
117
-
-
0037163023
-
Reconstitution of enzymatic activity by the association of the cap and catalytic domains of human topoisomerase I
-
Yang Z, Champoux JJ (2002) Reconstitution of enzymatic activity by the association of the cap and catalytic domains of human topoisomerase I. J Biol Chem 277(34): 30815-30823
-
(2002)
J Biol Chem
, vol.277
, Issue.34
, pp. 30815-30823
-
-
Yang, Z.1
Champoux, J.J.2
-
118
-
-
0025647116
-
Eukaryotic topoisomerases recognize nucleic acid topology by preferentially interacting with DNA crossovers
-
Zechiedrich EL, Osheroff N (1990) Eukaryotic topoisomerases recognize nucleic acid topology by preferentially interacting with DNA crossovers. Embo J 9(13): 4555-4562
-
(1990)
Embo J
, vol.9
, Issue.13
, pp. 4555-4562
-
-
Zechiedrich, E.L.1
Osheroff, N.2
-
119
-
-
0035845529
-
Human mitochondrial topoisomerase I
-
Zhang H, Barcelo JM, Lee B, Kohlhagen G, Zimonjic DB, Popescu NC, Pommier Y (2001) Human mitochondrial topoisomerase I. Proc Natl Acad Sci USA 98(19): 10608-10613
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, Issue.19
, pp. 10608-10613
-
-
Zhang, H.1
Barcelo, J.M.2
Lee, B.3
Kohlhagen, G.4
Zimonjic, D.B.5
Popescu, N.C.6
Pommier, Y.7
-
120
-
-
0023958908
-
Involvement of DNA topoisomerase I in transcription of human ribosomal RNA genes
-
Zhang H, Wang JC, Liu LF (1988) Involvement of DNA topoisomerase I in transcription of human ribosomal RNA genes. Proc Natl Acad Sci USA 85(4): 1060-1064
-
(1988)
Proc Natl Acad Sci USA
, vol.85
, Issue.4
, pp. 1060-1064
-
-
Zhang, H.1
Wang, J.C.2
Liu, L.F.3
|