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Volumn , Issue , 2012, Pages 53-69

Human DNA topoisomerase I: Structure, enzymology and biology

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EID: 84899786642     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1007/978-1-4614-0323-4_2     Document Type: Chapter
Times cited : (2)

References (120)
  • 1
    • 0026632325 scopus 로고
    • Identification of an N-terminal domain of eukaryotic DNA topoisomerase I dispensable for catalytic activity but essential for in vivo function
    • Alsner J, Svejstrup JQ, Kjeldsen E, Sorensen BS, Westergaard O (1992) Identification of an N-terminal domain of eukaryotic DNA topoisomerase I dispensable for catalytic activity but essential for in vivo function. J Biol Chem 267(18): 12408-12411
    • (1992) J Biol Chem , vol.267 , Issue.18 , pp. 12408-12411
    • Alsner, J.1    Svejstrup, J.Q.2    Kjeldsen, E.3    Sorensen, B.S.4    Westergaard, O.5
  • 3
    • 0023807621 scopus 로고
    • Camptothecin, a specific inhibitor of type I DNA topoisomerase, induces DNA breakage at replication forks
    • Avemann K, Knippers R, Koller T, Sogo JM (1988) Camptothecin, a specific inhibitor of type I DNA topoisomerase, induces DNA breakage at replication forks. Mol Cell Biol 8(8): 3026-3034
    • (1988) Mol Cell Biol , vol.8 , Issue.8 , pp. 3026-3034
    • Avemann, K.1    Knippers, R.2    Koller, T.3    Sogo, J.M.4
  • 4
    • 0028795337 scopus 로고
    • Cell cycle analysis of amount and distribution of nuclear DNA topoisomerase I as determined by fluorescence digital imaging microscopy
    • Baker SD, Wadkins RM, Stewart CF, Beck WT, Danks MK (1995) Cell cycle analysis of amount and distribution of nuclear DNA topoisomerase I as determined by fluorescence digital imaging microscopy. Cytometry 19(2): 134-145
    • (1995) Cytometry , vol.19 , Issue.2 , pp. 134-145
    • Baker, S.D.1    Wadkins, R.M.2    Stewart, C.F.3    Beck, W.T.4    Danks, M.K.5
  • 5
    • 37049037760 scopus 로고    scopus 로고
    • Serine phosphorylation-dependent coregulation of topoisomerase I by the p14ARF tumor suppressor
    • Bandyopadhyay K, Lee C, Haghighi A, Baneres JL, Parello J, Gjerset RA (2007) Serine phosphorylation-dependent coregulation of topoisomerase I by the p14ARF tumor suppressor. Biochemistry 46(49): 14325-14334
    • (2007) Biochemistry , vol.46 , Issue.49 , pp. 14325-14334
    • Bandyopadhyay, K.1    Lee, C.2    Haghighi, A.3    Baneres, J.L.4    Parello, J.5    Gjerset, R.A.6
  • 6
    • 0035850913 scopus 로고    scopus 로고
    • Molecular interactions between poly(ADP-ribose) polymerase (PARP I) and topoisomerase I (Topo I): Identification of topology of binding
    • Bauer PI, Chen HJ, Kenesi E, Kenessey I, Buki KG, Kirsten E, Hakam A, Hwang JI, Kun E (2001) Molecular interactions between poly(ADP-ribose) polymerase (PARP I) and topoisomerase I (Topo I): identification of topology of binding. FEBS Lett 506(3): 239-242
    • (2001) FEBS Lett , vol.506 , Issue.3 , pp. 239-242
    • Bauer, P.I.1    Chen, H.J.2    Kenesi, E.3    Kenessey, I.4    Buki, K.G.5    Kirsten, E.6    Hakam, A.7    Hwang, J.I.8    Kun, E.9
  • 7
    • 0021760306 scopus 로고
    • Nucleotide sequence preference at rat liver and wheat germ type 1 DNA topoisomerase breakage sites in duplex SV40 DNA
    • Been MD, Burgess RR, Champoux JJ (1984) Nucleotide sequence preference at rat liver and wheat germ type 1 DNA topoisomerase breakage sites in duplex SV40 DNA. Nucleic Acids Res 12(7): 3097-3114
    • (1984) Nucleic Acids Res , vol.12 , Issue.7 , pp. 3097-3114
    • Been, M.D.1    Burgess, R.R.2    Champoux, J.J.3
  • 8
    • 0019568339 scopus 로고
    • DNA breakage and closure by rat liver type 1 topoisomerase: Separation of the half-reactions by using a single-stranded DNA substrate
    • Been MD, Champoux JJ (1981) DNA breakage and closure by rat liver type 1 topoisomerase: separation of the half-reactions by using a single-stranded DNA substrate. Proc Natl Acad Sci USA 78(5): 2883-2887
    • (1981) Proc Natl Acad Sci USA , vol.78 , Issue.5 , pp. 2883-2887
    • Been, M.D.1    Champoux, J.J.2
  • 10
    • 0022369729 scopus 로고
    • A high affinity topoisomerase I binding sequence is clustered at DNAase I hypersensitive sites in Tetrahymena R-chromatin
    • Bonven BJ, Gocke E, Westergaard O (1985) A high affinity topoisomerase I binding sequence is clustered at DNAase I hypersensitive sites in Tetrahymena R-chromatin. Cell 41(2): 541-551
    • (1985) Cell , vol.41 , Issue.2 , pp. 541-551
    • Bonven, B.J.1    Gocke, E.2    Westergaard, O.3
  • 12
    • 0023639882 scopus 로고
    • DNA topoisomerase activity is required as a swivel for DNA replication and for ribosomal RNA transcription
    • Brill SJ, DiNardo S, Voelkel-Meiman K, Sternglanz R (1987) DNA topoisomerase activity is required as a swivel for DNA replication and for ribosomal RNA transcription. NCI Monogr 4: 11-15
    • (1987) NCI Monogr , vol.4 , pp. 11-15
    • Brill, S.J.1    DiNardo, S.2    Voelkel-meiman, K.3    Sternglanz, R.4
  • 13
    • 0022409106 scopus 로고
    • Association of crossover points with topoisomerase I cleavage sites: A model for nonhomologous recombination
    • Bullock P, Champoux JJ, Botchan M (1985) Association of crossover points with topoisomerase I cleavage sites: a model for nonhomologous recombination. Science 230(4728): 954-958
    • (1985) Science , vol.230 , Issue.4728 , pp. 954-958
    • Bullock, P.1    Champoux, J.J.2    Botchan, M.3
  • 14
    • 0024297005 scopus 로고
    • Eukaryotic DNA topoisomerase I reaction is topology dependent
    • Camilloni G, Di Martino E, Caserta M, di Mauro E (1988) Eukaryotic DNA topoisomerase I reaction is topology dependent. Nucleic Acids Res 16(14B): 7071-7085
    • (1988) Nucleic Acids Res , vol.16 , Issue.14 B , pp. 7071-7085
    • Camilloni, G.1    Di Martino, E.2    Caserta, M.3    di Mauro, E.4
  • 15
    • 0037948842 scopus 로고    scopus 로고
    • DNA relaxation by human topoisomerase I occurs in the closed clamp conformation of the protein
    • Carey JF, Schultz SJ, Sisson L, Fazzio TG, Champoux JJ (2003) DNA relaxation by human topoisomerase I occurs in the closed clamp conformation of the protein. Proc Natl Acad Sci USA 100(10): 5640-5645
    • (2003) Proc Natl Acad Sci USA , vol.100 , Issue.10 , pp. 5640-5645
    • Carey, J.F.1    Schultz, S.J.2    Sisson, L.3    Fazzio, T.G.4    Champoux, J.J.5
  • 16
    • 0036690387 scopus 로고    scopus 로고
    • Hyperphosphorylated C-terminal repeat domain-associating proteins in the nuclear proteome link transcription to DNA/chromatin modification and RNA processing
    • Carty SM, Greenleaf AL (2002) Hyperphosphorylated C-terminal repeat domain-associating proteins in the nuclear proteome link transcription to DNA/chromatin modification and RNA processing. Mol Cell Proteomics 1(8): 598-610
    • (2002) Mol Cell Proteomics , vol.1 , Issue.8 , pp. 598-610
    • Carty, S.M.1    Greenleaf, A.L.2
  • 17
    • 0025075146 scopus 로고
    • Regulation of the function of eukaryotic DNA topoisomerase I: Analysis of the binding step and of the catalytic constants of topoisomerization as a function of DNA topology
    • Caserta M, Amadei A, Camilloni G, Di Mauro E (1990) Regulation of the function of eukaryotic DNA topoisomerase I: analysis of the binding step and of the catalytic constants of topoisomerization as a function of DNA topology. Biochemistry 29(35): 8152-8157
    • (1990) Biochemistry , vol.29 , Issue.35 , pp. 8152-8157
    • Caserta, M.1    Amadei, A.2    Camilloni, G.3    Di Mauro, E.4
  • 19
    • 0002827166 scopus 로고
    • Evidence for an intermediate with a single-strand break in the reaction catalyzed by the DNA untwisting enzyme
    • Champoux JJ (1976) Evidence for an intermediate with a single-strand break in the reaction catalyzed by the DNA untwisting enzyme. Proc Natl Acad Sci USA 73(10): 3488-3491
    • (1976) Proc Natl Acad Sci USA , vol.73 , Issue.10 , pp. 3488-3491
    • Champoux, J.J.1
  • 20
    • 0017708066 scopus 로고
    • Strand breakage by the DNA untwisting enzyme results in covalent attachment of the enzyme to DNA
    • Champoux JJ (1977) Strand breakage by the DNA untwisting enzyme results in covalent attachment of the enzyme to DNA. Proc Natl Acad Sci USA 74(9): 3800-3804
    • (1977) Proc Natl Acad Sci USA , vol.74 , Issue.9 , pp. 3800-3804
    • Champoux, J.J.1
  • 21
    • 0026654950 scopus 로고
    • Topoisomerase I is preferentially associated with normal SV40 replicative intermediates, but is associated with both replicating and nonreplicating SV40 DNAs which are deficient in histones
    • Champoux JJ (1992) Topoisomerase I is preferentially associated with normal SV40 replicative intermediates, but is associated with both replicating and nonreplicating SV40 DNAs which are deficient in histones. Nucleic Acids Res 20(13): 3347-3352
    • (1992) Nucleic Acids Res , vol.20 , Issue.13 , pp. 3347-3352
    • Champoux, J.J.1
  • 22
    • 0034923502 scopus 로고    scopus 로고
    • DNA topoisomerases: Structure, function, and mechanism
    • Champoux JJ (2001) DNA topoisomerases: structure, function, and mechanism. Annu Rev Biochem 70: 369-413
    • (2001) Annu Rev Biochem , vol.70 , pp. 369-413
    • Champoux, J.J.1
  • 23
    • 0021646231 scopus 로고
    • DNA structural features that lead to strand breakage by eukaryotic type-I topoisomerase
    • Champoux JJ, McCoubrey WK, Jr., Been MD (1984) DNA structural features that lead to strand breakage by eukaryotic type-I topoisomerase. Cold Spring Harb Symp Quant Biol 49: 435-442
    • (1984) Cold Spring Harb Symp Quant Biol , vol.49 , pp. 435-442
    • Champoux, J.J.1    McCoubrey, W.K.2    Been, M.D.3
  • 24
    • 2542490127 scopus 로고    scopus 로고
    • Distinct effects of topoisomerase I and RNA polymerase I inhibitors suggest a dual mechanism of nucleolar/nucleoplasmic partitioning of topoisomerase I
    • Christensen MO, Krokowski RM, Barthelmes HU, Hock R, Boege F, Mielke C (2004) Distinct effects of topoisomerase I and RNA polymerase I inhibitors suggest a dual mechanism of nucleolar/nucleoplasmic partitioning of topoisomerase I. J Biol Chem 279(21): 21873-21882
    • (2004) J Biol Chem , vol.279 , Issue.21 , pp. 21873-21882
    • Christensen, M.O.1    Krokowski, R.M.2    Barthelmes, H.U.3    Hock, R.4    Boege, F.5    Mielke, C.6
  • 25
    • 31144446588 scopus 로고    scopus 로고
    • Papillomavirus E1 protein binds to and stimulates human topoisomerase I
    • Clower RV, Fisk JC, Melendy T (2006a) Papillomavirus E1 protein binds to and stimulates human topoisomerase I. J Virol 80(3): 1584-1587
    • (2006) J Virol , vol.80 , Issue.3 , pp. 1584-1587
    • Clower, R.V.1    Fisk, J.C.2    Melendy, T.3
  • 26
    • 33646039334 scopus 로고    scopus 로고
    • Papillomavirus E2 protein interacts with and stimulates human topoisomerase I
    • Clower RV, Hu Y, Melendy T (2006b) Papillomavirus E2 protein interacts with and stimulates human topoisomerase I. Virology 348(1): 13-18
    • (2006) Virology , vol.348 , Issue.1 , pp. 13-18
    • Clower, R.V.1    Hu, Y.2    Melendy, T.3
  • 27
    • 34547498794 scopus 로고    scopus 로고
    • Fast dynamics of supercoiled DNA revealed by single-molecule experiments
    • Crut A, Koster DA, Seidel R, Wiggins CH, Dekker NH (2007) Fast dynamics of supercoiled DNA revealed by single-molecule experiments. Proc Natl Acad Sci USA 104(29): 11957-11962
    • (2007) Proc Natl Acad Sci USA , vol.104 , Issue.29 , pp. 11957-11962
    • Crut, A.1    Koster, D.A.2    Seidel, R.3    Wiggins, C.H.4    Dekker, N.H.5
  • 29
    • 33644821060 scopus 로고    scopus 로고
    • The structure of the transition state of the heterodimeric topoisomerase I of Leishmania donovani as a vanadate complex with nicked DNA
    • Davies DR, Mushtaq A, Interthal H, Champoux JJ, Hol WG (2006) The structure of the transition state of the heterodimeric topoisomerase I of Leishmania donovani as a vanadate complex with nicked DNA. J Mol Biol 357(4): 1202-1210
    • (2006) J Mol Biol , vol.357 , Issue.4 , pp. 1202-1210
    • Davies, D.R.1    Mushtaq, A.2    Interthal, H.3    Champoux, J.J.4    Hol, W.G.5
  • 30
    • 0242290326 scopus 로고    scopus 로고
    • Single mutation in the linker domain confers protein flexibility and camptothecin resistance to human topoisomerase I
    • Fiorani P, Bruselles A, Falconi M, Chillemi G, Desideri A, Benedetti P (2003) Single mutation in the linker domain confers protein flexibility and camptothecin resistance to human topoisomerase I. J Biol Chem 278(44): 43268-43275
    • (2003) J Biol Chem , vol.278 , Issue.44 , pp. 43268-43275
    • Fiorani, P.1    Bruselles, A.2    Falconi, M.3    Chillemi, G.4    Desideri, A.5    Benedetti, P.6
  • 31
    • 73349101566 scopus 로고    scopus 로고
    • Evidence of the crucial role of the linker domain on the catalytic activity of human topoisomerase I by experimental and simulative characterization of the Lys681Ala mutant
    • Fiorani P, Tesauro C, Mancini G, Chillemi G, D'Annessa I, Graziani G, Tentori L, Muzi A, Desideri A (2009) Evidence of the crucial role of the linker domain on the catalytic activity of human topoisomerase I by experimental and simulative characterization of the Lys681Ala mutant. Nucleic Acids Res 37(20): 6849-6858
    • (2009) Nucleic Acids Res , vol.37 , Issue.20 , pp. 6849-6858
    • Fiorani, P.1    Tesauro, C.2    Mancini, G.3    Chillemi, G.4    D'Annessa, I.5    Graziani, G.6    Tentori, L.7    Muzi, A.8    Desideri, A.9
  • 33
    • 0347130921 scopus 로고    scopus 로고
    • Regions within the N-terminal domain of human topoisomerase I exert important functions during strand rotation and DNA binding
    • Frohlich RF, Andersen FF, Westergaard O, Andersen AH, Knudsen BR (2004) Regions within the N-terminal domain of human topoisomerase I exert important functions during strand rotation and DNA binding. J Mol Biol 336(1): 93-103
    • (2004) J Mol Biol , vol.336 , Issue.1 , pp. 93-103
    • Frohlich, R.F.1    Andersen, F.F.2    Westergaard, O.3    Andersen, A.H.4    Knudsen, B.R.5
  • 35
    • 0022508558 scopus 로고
    • Topoisomerase I interacts with transcribed regions in Drosophila cells
    • Gilmour DS, Pflugfelder G, Wang JC, Lis JT (1986) Topoisomerase I interacts with transcribed regions in Drosophila cells. Cell 44(3): 401-407
    • (1986) Cell , vol.44 , Issue.3 , pp. 401-407
    • Gilmour, D.S.1    Pflugfelder, G.2    Wang, J.C.3    Lis, J.T.4
  • 37
    • 0033621189 scopus 로고    scopus 로고
    • The interaction between p53 and DNA topoisomerase I is regulated differently in cells with wild-type and mutant p53
    • Gobert C, Skladanowski A, Larsen AK (1999) The interaction between p53 and DNA topoisomerase I is regulated differently in cells with wild-type and mutant p53. Proc Natl Acad Sci USA 96(18): 10355-10360
    • (1999) Proc Natl Acad Sci USA , vol.96 , Issue.18 , pp. 10355-10360
    • Gobert, C.1    Skladanowski, A.2    Larsen, A.K.3
  • 38
    • 69249212321 scopus 로고    scopus 로고
    • Automated comparative protein structure modeling with SWISS-MODEL and Swiss-PdbViewer: A historical perspective
    • Guex N, Peitsch MC, Schwede T (2009) Automated comparative protein structure modeling with SWISS-MODEL and Swiss-PdbViewer: a historical perspective. Electrophoresis 30 Suppl 1: S162-173
    • (2009) Electrophoresis , vol.30 , pp. S162-S173
    • Guex, N.1    Peitsch, M.C.2    Schwede, T.3
  • 40
    • 2642694700 scopus 로고    scopus 로고
    • Interaction between the N-terminus of human topoisomerase I and SV40 large T antigen
    • Haluska P, Jr., Saleem A, Edwards TK, Rubin EH (1998) Interaction between the N-terminus of human topoisomerase I and SV40 large T antigen. Nucleic Acids Res 26(7): 1841-1847
    • (1998) Nucleic Acids Res , vol.26 , Issue.7 , pp. 1841-1847
    • Haluska, P.1    Saleem, A.2    Edwards, T.K.3    Rubin, E.H.4
  • 41
    • 0345298272 scopus 로고    scopus 로고
    • Interaction between human topoisomerase I and a novel RING finger/arginine-serine protein
    • Haluska P, Jr., Saleem A, Rasheed Z, Ahmed F, Su EW, Liu LF, Rubin EH (1999) Interaction between human topoisomerase I and a novel RING finger/arginine-serine protein. Nucleic Acids Res 27(12): 2538-2544
    • (1999) Nucleic Acids Res , vol.27 , Issue.12 , pp. 2538-2544
    • Haluska, P.1    Saleem, A.2    Rasheed, Z.3    Ahmed, F.4    Su, E.W.5    Liu, L.F.6    Rubin, E.H.7
  • 42
    • 36048929872 scopus 로고    scopus 로고
    • The E3 ligase Topors induces the accumulation of polysumoylated forms of DNA topoisomerase I in vitro and in vivo
    • Hammer E, Heilbronn R, Weger S (2007) The E3 ligase Topors induces the accumulation of polysumoylated forms of DNA topoisomerase I in vitro and in vivo. FEBS Lett 581(28): 5418-5424
    • (2007) FEBS Lett , vol.581 , Issue.28 , pp. 5418-5424
    • Hammer, E.1    Heilbronn, R.2    Weger, S.3
  • 43
    • 0034652329 scopus 로고    scopus 로고
    • Closing the ring: Links between SMC proteins and chromosome partitioning, condensation, and supercoiling
    • Holmes VF, Cozzarelli NR (2000) Closing the ring: links between SMC proteins and chromosome partitioning, condensation, and supercoiling. Proc Natl Acad Sci USA 97(4): 1322-1324
    • (2000) Proc Natl Acad Sci USA , vol.97 , Issue.4 , pp. 1322-1324
    • Holmes, V.F.1    Cozzarelli, N.R.2
  • 44
    • 0022340594 scopus 로고
    • Camptothecin induces protein-linked DNA breaks via mammalian DNA topoisomerase I
    • Hsiang YH, Hertzberg R, Hecht S, Liu LF (1985) Camptothecin induces protein-linked DNA breaks via mammalian DNA topoisomerase I. J Biol Chem 260(27): 14873-14878
    • (1985) J Biol Chem , vol.260 , Issue.27 , pp. 14873-14878
    • Hsiang, Y.H.1    Hertzberg, R.2    Hecht, S.3    Liu, L.F.4
  • 46
    • 1642453632 scopus 로고    scopus 로고
    • The role of lysine 532 in the catalytic mechanism of human topoisomerase I
    • Interthal H, Quigley PM, Hol WG, Champoux JJ (2004) The role of lysine 532 in the catalytic mechanism of human topoisomerase I. J Biol Chem 279(4): 2984-2992
    • (2004) J Biol Chem , vol.279 , Issue.4 , pp. 2984-2992
    • Interthal, H.1    Quigley, P.M.2    Hol, W.G.3    Champoux, J.J.4
  • 47
    • 0021111554 scopus 로고
    • Association of eukaryotic DNA topoisomerase I with nucleosomes and chromosomal proteins
    • Javaherian K, Liu LF (1983) Association of eukaryotic DNA topoisomerase I with nucleosomes and chromosomal proteins. Nucleic Acids Res 11(2): 461-472
    • (1983) Nucleic Acids Res , vol.11 , Issue.2 , pp. 461-472
    • Javaherian, K.1    Liu, L.F.2
  • 48
    • 0025719903 scopus 로고
    • Effect of local DNA sequence on topoisomerase I cleavage in the presence or absence of camptothecin
    • Jaxel C, Capranico G, Kerrigan D, Kohn KW, Pommier Y (1991) Effect of local DNA sequence on topoisomerase I cleavage in the presence or absence of camptothecin. J Biol Chem 266(30): 20418-20423
    • (1991) J Biol Chem , vol.266 , Issue.30 , pp. 20418-20423
    • Jaxel, C.1    Capranico, G.2    Kerrigan, D.3    Kohn, K.W.4    Pommier, Y.5
  • 49
    • 0035864758 scopus 로고    scopus 로고
    • Human ARF protein interacts with topoisomerase I and stimulates its activity
    • Karayan L, Riou JF, Seite P, Migeon J, Cantereau A, Larsen CJ (2001) Human ARF protein interacts with topoisomerase I and stimulates its activity. Oncogene 20(7): 836-848
    • (2001) Oncogene , vol.20 , Issue.7 , pp. 836-848
    • Karayan, L.1    Riou, J.F.2    Seite, P.3    Migeon, J.4    Cantereau, A.5    Larsen, C.J.6
  • 50
    • 0024338961 scopus 로고
    • Function of DNA topoisomerases as replication swivels in Saccharomyces cerevisiae
    • Kim RA, Wang JC (1989) Function of DNA topoisomerases as replication swivels in Saccharomyces cerevisiae. J Mol Biol 208(2): 257-267
    • (1989) J Mol Biol , vol.208 , Issue.2 , pp. 257-267
    • Kim, R.A.1    Wang, J.C.2
  • 51
    • 0033597962 scopus 로고    scopus 로고
    • 13S condensin actively reconfigures DNA by introducing global positive writhe: Implications for chromosome condensation
    • Kimura K, Rybenkov VV, Crisona NJ, Hirano T, Cozzarelli NR (1999) 13S condensin actively reconfigures DNA by introducing global positive writhe: implications for chromosome condensation. Cell 98(2): 239-248
    • (1999) Cell , vol.98 , Issue.2 , pp. 239-248
    • Kimura, K.1    Rybenkov, V.V.2    Crisona, N.J.3    Hirano, T.4    Cozzarelli, N.R.5
  • 52
    • 0034570196 scopus 로고    scopus 로고
    • How do drug-induced topoisomerase I-DNA lesions signal to the molecular interaction network that regulates cell cycle checkpoints, DNA replication, and DNA repair?
    • Kohn KW, Shao RG, Pommier Y (2000) How do drug-induced topoisomerase I-DNA lesions signal to the molecular interaction network that regulates cell cycle checkpoints, DNA replication, and DNA repair? Cell Biochem Biophys 33(2): 175-180
    • (2000) Cell Biochem Biophys , vol.33 , Issue.2 , pp. 175-180
    • Kohn, K.W.1    Shao, R.G.2    Pommier, Y.3
  • 53
    • 15844383117 scopus 로고    scopus 로고
    • Friction and torque govern the relaxation of DNA supercoils by eukaryotic topoisomerase IB
    • Koster DA, Croquette V, Dekker C, Shuman S, Dekker NH (2005) Friction and torque govern the relaxation of DNA supercoils by eukaryotic topoisomerase IB. Nature 434(7033): 671-674
    • (2005) Nature , vol.434 , Issue.7033 , pp. 671-674
    • Koster, D.A.1    Croquette, V.2    Dekker, C.3    Shuman, S.4    Dekker, N.H.5
  • 54
    • 34447509295 scopus 로고    scopus 로고
    • Antitumour drugs impede DNA uncoiling by topoisomerase I
    • Koster DA, Palle K, Bot ES, Bjornsti MA, Dekker NH (2007) Antitumour drugs impede DNA uncoiling by topoisomerase I. Nature 448(7150): 213-217
    • (2007) Nature , vol.448 , Issue.7150 , pp. 213-217
    • Koster, D.A.1    Palle, K.2    Bot, E.S.3    Bjornsti, M.A.4    Dekker, N.H.5
  • 55
    • 0037503634 scopus 로고    scopus 로고
    • Activation of human topoisomerase I by protein kinase CK2
    • Kowalska-Loth B, Girstun A, Derlacz R, Staron K (2003) Activation of human topoisomerase I by protein kinase CK2. Mol Biol Rep 30(2): 107-111
    • (2003) Mol Biol Rep , vol.30 , Issue.2 , pp. 107-111
    • Kowalska-loth, B.1    Girstun, A.2    Derlacz, R.3    Staron, K.4
  • 56
    • 0027138674 scopus 로고
    • Identification of human DNA topoisomerase I as a cofactor for activator-dependent transcription by RNA polymerase II
    • Kretzschmar M, Meisterernst M, Roeder RG (1993) Identification of human DNA topoisomerase I as a cofactor for activator-dependent transcription by RNA polymerase II. Proc Natl Acad Sci USA 90(24): 11508-11512
    • (1993) Proc Natl Acad Sci USA , vol.90 , Issue.24 , pp. 11508-11512
    • Kretzschmar, M.1    Meisterernst, M.2    Roeder, R.G.3
  • 57
    • 0024431084 scopus 로고
    • Interaction of topoisomerase 1 with the transcribed region of the Drosophila HSP 70 heat shock gene
    • Kroeger PE, Rowe TC (1989) Interaction of topoisomerase 1 with the transcribed region of the Drosophila HSP 70 heat shock gene. Nucleic Acids Res 17(21): 8495-8509
    • (1989) Nucleic Acids Res , vol.17 , Issue.21 , pp. 8495-8509
    • Kroeger, P.E.1    Rowe, T.C.2
  • 58
    • 0032526604 scopus 로고    scopus 로고
    • Interaction between the N-terminal domain of human DNA topoisomerase I and the arginine-serine domain of its substrate determines phosphorylation of SF2/ASF splicing factor
    • Labourier E, Rossi F, Gallouzi IE, Allemand E, Divita G, Tazi J (1998) Interaction between the N-terminal domain of human DNA topoisomerase I and the arginine-serine domain of its substrate determines phosphorylation of SF2/ASF splicing factor. Nucleic Acids Res 26(12): 2955-2962
    • (1998) Nucleic Acids Res , vol.26 , Issue.12 , pp. 2955-2962
    • Labourier, E.1    Rossi, F.2    Gallouzi, I.E.3    Allemand, E.4    Divita, G.5    Tazi, J.6
  • 60
    • 0032759443 scopus 로고    scopus 로고
    • DNA topoisomerase I in oncology: Dr Jekyll or Mr Hyde?
    • Larsen AK, Gobert C (1999) DNA topoisomerase I in oncology: Dr Jekyll or Mr Hyde? Pathol Oncol Res 5(3): 171-178
    • (1999) Pathol Oncol Res , vol.5 , Issue.3 , pp. 171-178
    • Larsen, A.K.1    Gobert, C.2
  • 62
    • 42149171249 scopus 로고    scopus 로고
    • Trapping of human DNA topoisomerase I by DNA structures mimicking intermediates of DNA repair
    • Lebedeva N, Rechkunova N, Boiteux S, Lavrik O (2008) Trapping of human DNA topoisomerase I by DNA structures mimicking intermediates of DNA repair. IUBMB Life 60(2): 130-134
    • (2008) IUBMB Life , vol.60 , Issue.2 , pp. 130-134
    • Lebedeva, N.1    Rechkunova, N.2    Boiteux, S.3    Lavrik, O.4
  • 63
    • 0033621354 scopus 로고    scopus 로고
    • The Werner syndrome gene product co-purifies with the DNA replication complex and interacts with PCNA and topoisomerase I
    • Lebel M, Spillare EA, Harris CC, Leder P (1999) The Werner syndrome gene product co-purifies with the DNA replication complex and interacts with PCNA and topoisomerase I. J Biol Chem 274(53): 37795-37799
    • (1999) J Biol Chem , vol.274 , Issue.53 , pp. 37795-37799
    • Lebel, M.1    Spillare, E.A.2    Harris, C.C.3    Leder, P.4
  • 64
    • 0027165312 scopus 로고
    • DNA topoisomerase I is essential in Drosophila melanogaster
    • Lee MP, Brown SD, Chen A, Hsieh TS (1993) DNA topoisomerase I is essential in Drosophila melanogaster. Proc Natl Acad Sci USA 90(14): 6656-6660
    • (1993) Proc Natl Acad Sci USA , vol.90 , Issue.14 , pp. 6656-6660
    • Lee, M.P.1    Brown, S.D.2    Chen, A.3    Hsieh, T.S.4
  • 65
    • 0037047088 scopus 로고    scopus 로고
    • Potent stimulation of transcription-coupled DNA supercoiling by sequence-specific DNA-binding proteins
    • Leng F, McMacken R (2002) Potent stimulation of transcription-coupled DNA supercoiling by sequence-specific DNA-binding proteins. Proc Natl Acad Sci USA 99(14): 9139-9144
    • (2002) Proc Natl Acad Sci USA , vol.99 , Issue.14 , pp. 9139-9144
    • Leng, F.1    McMacken, R.2
  • 66
    • 22744457037 scopus 로고    scopus 로고
    • Human DNA topoisomerase I: Relaxation, roles, and damage control
    • Leppard JB, Champoux JJ (2005) Human DNA topoisomerase I: relaxation, roles, and damage control. Chromosoma 114(2): 75-85
    • (2005) Chromosoma , vol.114 , Issue.2 , pp. 75-85
    • Leppard, J.B.1    Champoux, J.J.2
  • 68
    • 0023433855 scopus 로고
    • Supercoiling of the DNA template during transcription
    • Liu LF, Wang JC (1987) Supercoiling of the DNA template during transcription. Proc Natl Acad Sci USA 84(20): 7024-7027
    • (1987) Proc Natl Acad Sci USA , vol.84 , Issue.20 , pp. 7024-7027
    • Liu, L.F.1    Wang, J.C.2
  • 69
    • 34248147699 scopus 로고    scopus 로고
    • Alterations in linker flexibility suppress DNA topoisomerase I mutant-induced cell lethality
    • Losasso C, Cretaio E, Palle K, Pattarello L, Bjornsti MA, Benedetti P (2007) Alterations in linker flexibility suppress DNA topoisomerase I mutant-induced cell lethality. J Biol Chem 282(13): 9855-9864
    • (2007) J Biol Chem , vol.282 , Issue.13 , pp. 9855-9864
    • Losasso, C.1    Cretaio, E.2    Palle, K.3    Pattarello, L.4    Bjornsti, M.A.5    Benedetti, P.6
  • 70
    • 0028787255 scopus 로고
    • Preferential binding of human topoisomerase I to superhelical DNA
    • Madden KR, Stewart L, Champoux JJ (1995) Preferential binding of human topoisomerase I to superhelical DNA. EMBO J 14(21): 5399-5409
    • (1995) EMBO J , vol.14 , Issue.21 , pp. 5399-5409
    • Madden, K.R.1    Stewart, L.2    Champoux, J.J.3
  • 71
    • 1242339684 scopus 로고    scopus 로고
    • Poly(ADP-ribose) reactivates stalled DNA topoisomerase I and Induces DNA strand break resealing
    • Malanga M, Althaus FR (2004) Poly(ADP-ribose) reactivates stalled DNA topoisomerase I and Induces DNA strand break resealing. J Biol Chem 279(7): 5244-5248
    • (2004) J Biol Chem , vol.279 , Issue.7 , pp. 5244-5248
    • Malanga, M.1    Althaus, F.R.2
  • 72
    • 0037022269 scopus 로고    scopus 로고
    • Subnuclear distribution of topoisomerase I is linked to ongoing transcription and p53 status
    • Mao Y, Mehl IR, Muller MT (2002) Subnuclear distribution of topoisomerase I is linked to ongoing transcription and p53 status. Proc Natl Acad Sci USA 99(3): 1235-1240
    • (2002) Proc Natl Acad Sci USA , vol.99 , Issue.3 , pp. 1235-1240
    • Mao, Y.1    Mehl, I.R.2    Muller, M.T.3
  • 73
    • 0034635958 scopus 로고    scopus 로고
    • SUMO-1 conjugation to topoisomerase I: A possible repair response to topoisomerase-mediated DNA damage
    • Mao Y, Sun M, Desai SD, Liu LF (2000) SUMO-1 conjugation to topoisomerase I: A possible repair response to topoisomerase-mediated DNA damage. Proc Natl Acad Sci USA 97(8): 4046-4051
    • (2000) Proc Natl Acad Sci USA , vol.97 , Issue.8 , pp. 4046-4051
    • Mao, Y.1    Sun, M.2    Desai, S.D.3    Liu, L.F.4
  • 74
    • 0027186443 scopus 로고
    • DNA topoisomerase I is involved in both repression and activation of transcription
    • Merino A, Madden KR, Lane WS, Champoux JJ, Reinberg D (1993) DNA topoisomerase I is involved in both repression and activation of transcription. Nature 365(6443): 227-232
    • (1993) Nature , vol.365 , Issue.6443 , pp. 227-232
    • Merino, A.1    Madden, K.R.2    Lane, W.S.3    Champoux, J.J.4    Reinberg, D.5
  • 77
    • 0034731326 scopus 로고    scopus 로고
    • A novel nuclear localization signal in human DNA topoisomerase I
    • Mo YY, Wang C, Beck WT (2000) A novel nuclear localization signal in human DNA topoisomerase I. J Biol Chem 275(52): 41107-41113
    • (2000) J Biol Chem , vol.275 , Issue.52 , pp. 41107-41113
    • Mo, Y.Y.1    Wang, C.2    Beck, W.T.3
  • 78
    • 0029912651 scopus 로고    scopus 로고
    • Targeted disruption of the mouse topoisomerase I gene by camptothecin selection
    • Morham SG, Kluckman KD, Voulomanos N, Smithies O (1996) Targeted disruption of the mouse topoisomerase I gene by camptothecin selection. Mol Cell Biol 16(12): 6804-6809
    • (1996) Mol Cell Biol , vol.16 , Issue.12 , pp. 6804-6809
    • Morham, S.G.1    Kluckman, K.D.2    Voulomanos, N.3    Smithies, O.4
  • 80
    • 0022067647 scopus 로고
    • Eukaryotic type I topoisomerase is enriched in the nucleolus and catalytically active on ribosomal DNA
    • Muller MT, Pfund WP, Mehta VB, Trask DK (1985) Eukaryotic type I topoisomerase is enriched in the nucleolus and catalytically active on ribosomal DNA. Embo J 4(5): 1237-1243
    • (1985) Embo J , vol.4 , Issue.5 , pp. 1237-1243
    • Muller, M.T.1    Pfund, W.P.2    Mehta, V.B.3    Trask, D.K.4
  • 81
    • 0033405042 scopus 로고    scopus 로고
    • Transport of torsional stress in DNA
    • Nelson P (1999) Transport of torsional stress in DNA. Proc Natl Acad Sci USA 96(25): 14342-14347
    • (1999) Proc Natl Acad Sci USA , vol.96 , Issue.25 , pp. 14342-14347
    • Nelson, P.1
  • 82
    • 18144373451 scopus 로고    scopus 로고
    • Poly(ADP-ribose) polymerase-1 could facilitate the religation of topoisomerase I-linked DNA inhibited by camptothecin
    • Park SY, Cheng YC (2005) Poly(ADP-ribose) polymerase-1 could facilitate the religation of topoisomerase I-linked DNA inhibited by camptothecin. Cancer Res 65(9): 3894-3902
    • (2005) Cancer Res , vol.65 , Issue.9 , pp. 3894-3902
    • Park, S.Y.1    Cheng, Y.C.2
  • 83
    • 8844239149 scopus 로고    scopus 로고
    • The topoisomerase 1-interacting protein BTBD1 is essential for muscle cell differentiation
    • Pisani DF, Cabane C, Derijard B, Dechesne CA (2004) The topoisomerase 1-interacting protein BTBD1 is essential for muscle cell differentiation. Cell Death Differ 11(11): 1157-1165
    • (2004) Cell Death Differ , vol.11 , Issue.11 , pp. 1157-1165
    • Pisani, D.F.1    Cabane, C.2    Derijard, B.3    Dechesne, C.A.4
  • 85
    • 14644420930 scopus 로고    scopus 로고
    • Interfacial inhibition of macromolecular interactions: Nature's paradigm for drug discovery
    • Pommier Y, Cherfils J (2005) Interfacial inhibition of macromolecular interactions: nature's paradigm for drug discovery. Trends Pharmacol Sci 26(3): 138-145
    • (2005) Trends Pharmacol Sci , vol.26 , Issue.3 , pp. 138-145
    • Pommier, Y.1    Cherfils, J.2
  • 86
    • 0032189683 scopus 로고    scopus 로고
    • Mechanism of action of eukaryotic DNA topoisomerase I and drugs targeted to the enzyme
    • Pommier Y, Pourquier P, Fan Y, Strumberg D (1998) Mechanism of action of eukaryotic DNA topoisomerase I and drugs targeted to the enzyme. Biochim Biophys Acta 1400(1-3): 83-105
    • (1998) Biochim Biophys Acta , vol.1400 , Issue.1-3 , pp. 83-105
    • Pommier, Y.1    Pourquier, P.2    Fan, Y.3    Strumberg, D.4
  • 88
    • 0024469050 scopus 로고
    • The basis for camptothecin enhancement of DNA breakage by eukaryotic topoisomerase I
    • Porter SE, Champoux JJ (1989) The basis for camptothecin enhancement of DNA breakage by eukaryotic topoisomerase I. Nucleic Acids Res 17(21): 8521-8532
    • (1989) Nucleic Acids Res , vol.17 , Issue.21 , pp. 8521-8532
    • Porter, S.E.1    Champoux, J.J.2
  • 89
    • 0034643810 scopus 로고    scopus 로고
    • Novel Insights into Catalytic Mechanism from a Crystal Structure of Human Topoisomerase I in Complex with DNA
    • Redinbo MR, Champoux JJ, Hol WG (2000) Novel Insights into Catalytic Mechanism from a Crystal Structure of Human Topoisomerase I in Complex with DNA. Biochemistry 39(23): 6832-6840
    • (2000) Biochemistry , vol.39 , Issue.23 , pp. 6832-6840
    • Redinbo, M.R.1    Champoux, J.J.2    Hol, W.G.3
  • 90
    • 0000734623 scopus 로고    scopus 로고
    • Structural flexibility in human topoisomerase I revealed in multiple non-isomorphous crystal structures
    • Redinbo MR, Stewart L, Champoux JJ, Hol WG (1999) Structural flexibility in human topoisomerase I revealed in multiple non-isomorphous crystal structures. J Mol Biol 292(3): 685-696
    • (1999) J Mol Biol , vol.292 , Issue.3 , pp. 685-696
    • Redinbo, M.R.1    Stewart, L.2    Champoux, J.J.3    Hol, W.G.4
  • 91
    • 0032489634 scopus 로고    scopus 로고
    • Crystal structures of human topoisomerase I in covalent and noncovalent complexes with DNA
    • Redinbo MR, Stewart L, Kuhn P, Champoux JJ, Hol WG (1998) Crystal structures of human topoisomerase I in covalent and noncovalent complexes with DNA. Science 279(5356): 1504-1513
    • (1998) Science , vol.279 , Issue.5356 , pp. 1504-1513
    • Redinbo, M.R.1    Stewart, L.2    Kuhn, P.3    Champoux, J.J.4    Hol, W.G.5
  • 92
    • 0021760689 scopus 로고
    • Structure of the nucleosome core particle at 7 A resolution
    • Richmond TJ, Finch JT, Rushton B, Rhodes D, Klug A (1984) Structure of the nucleosome core particle at 7 A resolution. Nature 311(5986): 532-537
    • (1984) Nature , vol.311 , Issue.5986 , pp. 532-537
    • Richmond, T.J.1    Finch, J.T.2    Rushton, B.3    Rhodes, D.4    Klug, A.5
  • 93
    • 33846102234 scopus 로고    scopus 로고
    • Cellular stress triggers the human topoisomerase I damage response independently of DNA damage in a p53 controlled manner
    • Rockstroh A, Kleinert A, Kramer M, Grosse F, Soe K (2007) Cellular stress triggers the human topoisomerase I damage response independently of DNA damage in a p53 controlled manner. Oncogene 26(1): 123-131
    • (2007) Oncogene , vol.26 , Issue.1 , pp. 123-131
    • Rockstroh, A.1    Kleinert, A.2    Kramer, M.3    Grosse, F.4    Soe, K.5
  • 94
    • 0023805882 scopus 로고
    • Association of DNA topoisomerase I and RNA polymerase I: A possible role for topoisomerase I in ribosomal gene transcription
    • Rose KM, Szopa J, Han FS, Cheng YC, Richter A, Scheer U (1988) Association of DNA topoisomerase I and RNA polymerase I: a possible role for topoisomerase I in ribosomal gene transcription. Chromosoma 96(6): 411-416
    • (1988) Chromosoma , vol.96 , Issue.6 , pp. 411-416
    • Rose, K.M.1    Szopa, J.2    Han, F.S.3    Cheng, Y.C.4    Richter, A.5    Scheer, U.6
  • 95
    • 33745762610 scopus 로고    scopus 로고
    • Topoisomerase II, not topoisomerase I, is the proficient relaxase of nucleosomal DNA
    • Salceda J, Fernandez X, Roca J (2006) Topoisomerase II, not topoisomerase I, is the proficient relaxase of nucleosomal DNA. Embo J 25(11): 2575-2583
    • (2006) Embo J , vol.25 , Issue.11 , pp. 2575-2583
    • Salceda, J.1    Fernandez, X.2    Roca, J.3
  • 96
    • 29144455886 scopus 로고    scopus 로고
    • Rotation of DNA around intact strand in human topoisomerase I implies distinct mechanisms for positive and negative supercoil relaxation
    • Sari L, Andricioaei I (2005) Rotation of DNA around intact strand in human topoisomerase I implies distinct mechanisms for positive and negative supercoil relaxation. Nucleic Acids Res 33(20): 6621-6634
    • (2005) Nucleic Acids Res , vol.33 , Issue.20 , pp. 6621-6634
    • Sari, L.1    Andricioaei, I.2
  • 98
    • 0025190947 scopus 로고
    • Rapid induction of c-fos transcription reveals quantitative linkage of RNA polymerase II and DNA topoisomerase I enzyme activities
    • Stewart AF, Herrera RE, Nordheim A (1990) Rapid induction of c-fos transcription reveals quantitative linkage of RNA polymerase II and DNA topoisomerase I enzyme activities. Cell 60(1): 141-149
    • (1990) Cell , vol.60 , Issue.1 , pp. 141-149
    • Stewart, A.F.1    Herrera, R.E.2    Nordheim, A.3
  • 99
    • 0029869828 scopus 로고    scopus 로고
    • The domain organization of human topoisomerase I
    • Stewart L, Ireton GC, Champoux JJ (1996) The domain organization of human topoisomerase I. J Biol Chem 271(13): 7602-7608
    • (1996) J Biol Chem , vol.271 , Issue.13 , pp. 7602-7608
    • Stewart, L.1    Ireton, G.C.2    Champoux, J.J.3
  • 100
    • 0031566428 scopus 로고    scopus 로고
    • Reconstitution of human topoisomerase I by fragment complementation
    • Stewart L, Ireton GC, Champoux JJ (1997) Reconstitution of human topoisomerase I by fragment complementation. J Mol Biol 269(3): 355-372
    • (1997) J Mol Biol , vol.269 , Issue.3 , pp. 355-372
    • Stewart, L.1    Ireton, G.C.2    Champoux, J.J.3
  • 101
    • 0032752373 scopus 로고    scopus 로고
    • A functional linker in human topoisomerase I is required for maximum sensitivity to camptothecin in a DNA relaxation assay
    • Stewart L, Ireton GC, Champoux JJ (1999) A functional linker in human topoisomerase I is required for maximum sensitivity to camptothecin in a DNA relaxation assay. J Biol Chem 274(46): 32950-32960
    • (1999) J Biol Chem , vol.274 , Issue.46 , pp. 32950-32960
    • Stewart, L.1    Ireton, G.C.2    Champoux, J.J.3
  • 102
    • 0032489675 scopus 로고    scopus 로고
    • A model for the mechanism of human topoisomerase I
    • Stewart L, Redinbo MR, Qiu X, Hol WG, Champoux JJ (1998) A model for the mechanism of human topoisomerase I. Science 279(5356): 1534-1541
    • (1998) Science , vol.279 , Issue.5356 , pp. 1534-1541
    • Stewart, L.1    Redinbo, M.R.2    Qiu, X.3    Hol, W.G.4    Champoux, J.J.5
  • 103
    • 0028091124 scopus 로고
    • Vaccinia DNA topoisomerase I: Single-turnover and steady-state kinetic analysis of the DNA strand cleavage and ligation reactions
    • Stivers JT, Shuman S, Mildvan AS (1994) Vaccinia DNA topoisomerase I: single-turnover and steady-state kinetic analysis of the DNA strand cleavage and ligation reactions. Biochemistry 33(1): 327-339
    • (1994) Biochemistry , vol.33 , Issue.1 , pp. 327-339
    • Stivers, J.T.1    Shuman, S.2    Mildvan, A.S.3
  • 104
  • 105
    • 0034630945 scopus 로고    scopus 로고
    • HTLV-1 tax oncoprotein binds to DNA topoisomerase I and inhibits its catalytic activity
    • Suzuki T, Uchida-Toita M, Andoh T, Yoshida M (2000) HTLV-1 tax oncoprotein binds to DNA topoisomerase I and inhibits its catalytic activity. Virology 270(2): 291-298
    • (2000) Virology , vol.270 , Issue.2 , pp. 291-298
    • Suzuki, T.1    Uchida-toita, M.2    Andoh, T.3    Yoshida, M.4
  • 106
    • 0027501814 scopus 로고
    • Induction of cleavage in topoisomerase I c-DNA by topoisomerase I enzymes from calf thymus and wheat germ in the presence and absence of camptothecin
    • Tanizawa A, Kohn KW, Pommier Y (1993) Induction of cleavage in topoisomerase I c-DNA by topoisomerase I enzymes from calf thymus and wheat germ in the presence and absence of camptothecin. Nucleic Acids Res 21(22): 5157-5166
    • (1993) Nucleic Acids Res , vol.21 , Issue.22 , pp. 5157-5166
    • Tanizawa, A.1    Kohn, K.W.2    Pommier, Y.3
  • 107
    • 19044400932 scopus 로고    scopus 로고
    • Rotational drag on DNA: A single molecule experiment
    • Thomen P, Bockelmann U, Heslot F (2002) Rotational drag on DNA: a single molecule experiment. Phys Rev Lett 88(24): 248102
    • (2002) Phys Rev Lett , vol.88 , Issue.24 , pp. 248102
    • Thomen, P.1    Bockelmann, U.2    Heslot, F.3
  • 108
    • 0021891888 scopus 로고
    • DNA topoisomerases
    • Wang JC (1985) DNA topoisomerases. Annu Rev Biochem 54: 665-697
    • (1985) Annu Rev Biochem , vol.54 , pp. 665-697
    • Wang, J.C.1
  • 109
    • 0030014783 scopus 로고    scopus 로고
    • DNA Topoisomerases
    • Wang JC (1996) DNA Topoisomerases. Ann Rev Biochem 65: 635-692
    • (1996) Ann Rev Biochem , vol.65 , pp. 635-692
    • Wang, J.C.1
  • 110
    • 0036085460 scopus 로고    scopus 로고
    • Cellular roles of DNA topoisomerases: A molecular perspective
    • Wang JC (2002) Cellular roles of DNA topoisomerases: a molecular perspective. Nat Rev Mol Cell Biol 3(6): 430-440
    • (2002) Nat Rev Mol Cell Biol , vol.3 , Issue.6 , pp. 430-440
    • Wang, J.C.1
  • 111
    • 0344702740 scopus 로고    scopus 로고
    • Locking the DNA topoisomerase I protein clamp inhibits DNA rotation and induces cell lethality
    • Woo MH, Losasso C, Guo H, Pattarello L, Benedetti P, Bjornsti MA (2003) Locking the DNA topoisomerase I protein clamp inhibits DNA rotation and induces cell lethality. Proc Natl Acad Sci USA 100(24): 13767-13772
    • (2003) Proc Natl Acad Sci USA , vol.100 , Issue.24 , pp. 13767-13772
    • Woo, M.H.1    Losasso, C.2    Guo, H.3    Pattarello, L.4    Benedetti, P.5    Bjornsti, M.A.6
  • 114
    • 0037495636 scopus 로고    scopus 로고
    • Characterization of BTBD1 and BTBD2, two similar BTB-domain-containing Kelch-like proteins that interact with Topoisomerase I
    • Xu L, Yang L, Hashimoto K, Anderson M, Kohlhagen G, Pommier Y, D'Arpa P (2002) Characterization of BTBD1 and BTBD2, two similar BTB-domain-containing Kelch-like proteins that interact with Topoisomerase I. BMC Genomics 3(1): 1
    • (2002) BMC Genomics , vol.3 , Issue.1 , pp. 1
    • Xu, L.1    Yang, L.2    Hashimoto, K.3    Anderson, M.4    Kohlhagen, G.5    Pommier, Y.6    D'Arpa, P.7
  • 115
    • 2642625363 scopus 로고
    • Roles of DNA topoisomerases in simian virus 40 DNA replication in vitro
    • Yang L, Wold MS, Li JJ, Kelly TJ, Liu LF (1987) Roles of DNA topoisomerases in simian virus 40 DNA replication in vitro. Proc Natl Acad Sci USA 84(4): 950-954
    • (1987) Proc Natl Acad Sci USA , vol.84 , Issue.4 , pp. 950-954
    • Yang, L.1    Wold, M.S.2    Li, J.J.3    Kelly, T.J.4    Liu, L.F.5
  • 116
    • 70349481519 scopus 로고    scopus 로고
    • Mutational analysis of the preferential binding of human topoisomerase I to supercoiled DNA
    • Yang Z, Carey JF, Champoux JJ (2009) Mutational analysis of the preferential binding of human topoisomerase I to supercoiled DNA. Febs J 276(20): 5906-5919
    • (2009) Febs J , vol.276 , Issue.20 , pp. 5906-5919
    • Yang, Z.1    Carey, J.F.2    Champoux, J.J.3
  • 117
    • 0037163023 scopus 로고    scopus 로고
    • Reconstitution of enzymatic activity by the association of the cap and catalytic domains of human topoisomerase I
    • Yang Z, Champoux JJ (2002) Reconstitution of enzymatic activity by the association of the cap and catalytic domains of human topoisomerase I. J Biol Chem 277(34): 30815-30823
    • (2002) J Biol Chem , vol.277 , Issue.34 , pp. 30815-30823
    • Yang, Z.1    Champoux, J.J.2
  • 118
    • 0025647116 scopus 로고
    • Eukaryotic topoisomerases recognize nucleic acid topology by preferentially interacting with DNA crossovers
    • Zechiedrich EL, Osheroff N (1990) Eukaryotic topoisomerases recognize nucleic acid topology by preferentially interacting with DNA crossovers. Embo J 9(13): 4555-4562
    • (1990) Embo J , vol.9 , Issue.13 , pp. 4555-4562
    • Zechiedrich, E.L.1    Osheroff, N.2
  • 120
    • 0023958908 scopus 로고
    • Involvement of DNA topoisomerase I in transcription of human ribosomal RNA genes
    • Zhang H, Wang JC, Liu LF (1988) Involvement of DNA topoisomerase I in transcription of human ribosomal RNA genes. Proc Natl Acad Sci USA 85(4): 1060-1064
    • (1988) Proc Natl Acad Sci USA , vol.85 , Issue.4 , pp. 1060-1064
    • Zhang, H.1    Wang, J.C.2    Liu, L.F.3


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